Primary Site >> Colorectal Cancer
Gene >> JAK1
| 1. | |||||||||||
| Journal: | J Biol Chem. 1995 Dec 22;270(51):30829-36. | ||||||||||
| Title: | Receptors for interleukin (IL)-4 do not associate with the common gamma chain, and IL-4 induces the phosphorylation of JAK2 tyrosine kinase in human colon carcinoma cells. | ||||||||||
| Author: | Murata, T|Noguchi, P D|Puri, R K | ||||||||||
| PMID: | 8530527 | ||||||||||
| 2. | |||||||||||
| Journal: | J Immunol. 1996 Apr 15;156(8):2972-8. | ||||||||||
| Title: | IL-13 induces phosphorylation and activation of JAK2 Janus kinase in human colon carcinoma cell lines: similarities between IL-4 and IL-13 signaling. | ||||||||||
| Author: | Murata, T|Noguchi, P D|Puri, R K | ||||||||||
| PMID: | 8609418 | ||||||||||
| 3. | |||||||||||
| Journal: | Int J Cancer. 1999 Nov 26;83(5):579-84. | ||||||||||
| Title: | Comparative tyrosine-kinase profiles in colorectal cancers: enhanced arg expression in carcinoma as compared with adenoma and normal mucosa. | ||||||||||
| Author: | Chen, W S|Kung, H J|Yang, W K|Lin, W c | ||||||||||
| PMID: | 10521789 | ||||||||||
| 4. | |||||||||||
| Journal: | J Cell Biochem. 2003 Dec 1;90(5):1026-37. | ||||||||||
| Title: | SHP-1 suppresses cancer cell growth by promoting degradation of JAK kinases. | ||||||||||
| Author: | Wu, Chengyu|Guan, Qin|Wang, Yingjian|Zhao, Z Joe|Zhou, G Wayne | ||||||||||
| PMID: | 14624462 | ||||||||||
| 5. | |||||||||||
| Journal: | J Biol Chem. 2004 Jul 16;279(29):30358-68. Epub 2004 May 3. | ||||||||||
| Title: | Requirement of histone deacetylase activity for signaling by STAT1. | ||||||||||
| Author: | Klampfer, Lidija|Huang, Jie|Swaby, Laurie-Anne|Augenlicht, Leonard | ||||||||||
| PMID: | 15123634 | ||||||||||
| 6. | |||||||||||
| Journal: | Oncogene. 2007 Mar 29;26(14):2133-5. Epub 2006 Oct 2. | ||||||||||
| Title: | Absence of tyrosine kinase mutations in Japanese colorectal cancer patients. | ||||||||||
| Author: | Shao, R-X|Kato, N|Lin, L-J|Muroyama, R|Moriyama, M|Ikenoue, T|Watabe, H|Otsuka, M|Guleng, B|Ohta, M|Tanaka, Y|Kondo, S|Dharel, N|Chang, J-H|Yoshida, H|Kawabe, T|Omata, M | ||||||||||
| PMID: | 17016444 | ||||||||||
| 7. | |||||||||||
| Journal: | Neoplasia. 2008 Mar;10(3):287-97. | ||||||||||
| Title: | Inhibition of JAK1, 2/STAT3 signaling induces apoptosis, cell cycle arrest, and reduces tumor cell invasion in colorectal cancer cells. | ||||||||||
| Author: | Xiong, Hua|Zhang, Zhi-Gang|Tian, Xiao-Qing|Sun, Dan-Feng|Liang, Qin-Chuan|Zhang, Yan-Jie|Lu, Rong|Chen, Ying-Xuan|Fang, Jing-Yuan | ||||||||||
| PMID: | 18320073 | ||||||||||
| 8. | |||||||||||
| Journal: | Exp Mol Med. 2009 Oct 31;41(10):717-27. | ||||||||||
| Title: | Triptolide downregulates Rac1 and the JAK/STAT3 pathway and inhibits colitis-related colon cancer progression. | ||||||||||
| Author: | Wang, Zhipeng|Jin, Haifeng|Xu, Ruodan|Mei, Qibing|Fan, Daiming | ||||||||||
| PMID: | 19561401 | ||||||||||
| 9. | |||||||||||
| Journal: | Mol Carcinog. 2013 Feb;52(2):155-66. | ||||||||||
| Title: | JAK/STAT/SOCS-signaling pathway and colon and rectal cancer. | ||||||||||
| Author: | Slattery, Martha L|Lundgreen, Abbie|Kadlubar, Susan A|Bondurant, Kristina L|Wolff, Roger K | ||||||||||
| PMID: | 22121102 | ||||||||||
| 10. | |||||||||||
| Journal: | Int J Oncol. 2013 Oct;43(4):1111-6. | ||||||||||
| Title: | Cancer upregulated gene 2, a novel oncogene, enhances migration and drug resistance of colon cancer cells via STAT1 activation. | ||||||||||
| Author: | Malilas, Waraporn|Koh, Sang Seok|Kim, Seokho|Srisuttee, Ratakorn|Cho, Il-Rae|Moon, Jeong|Yoo, Hwa-Seung|Oh, Sangtaek|Johnston, Randal N|Chung, Young-Hwa | ||||||||||
| PMID: | 23917355 | ||||||||||
| 11. | |||||||||||
| Journal: | Neoplasma. 2013 Sep 20. | ||||||||||
| Title: | INCB018424 induces apoptotic cell death through the suppression of pJAK1 in human colon cancer cells. | ||||||||||
| Author: | An, H J|Choi, E K|Kim, J S|Hong, S W|Moon, J H|Shin, J S|Ha, S H|Kim, K P|Hong, Y S|Lee, J L|Choi, E K|Lee, J S|Jin, D H|Kim, T W | ||||||||||
| PMID: | 24050550 | ||||||||||
| 12. | |||||||||||
| Journal: | BMC Cancer. 2013 Oct 8;13:463. | ||||||||||
| Title: | RKIP phosphorylation and STAT3 activation is inhibited by oxaliplatin and camptothecin and are associated with poor prognosis in stage II colon cancer patients. | ||||||||||
| Author: | Cross-Knorr, Sam|Lu, Shaolei|Perez, Kimberly|Guevara, Sara|Brilliant, Kate|Pisano, Claudio|Quesenberry, Peter J|Resnick, Murray B|Chatterjee, Devasis | ||||||||||
| PMID: | 24098947 | ||||||||||
| 13. | |||||||||||
| Journal: | Cell Rep. 2014 Jun 26;7(6):1940-55. | ||||||||||
| Title: | ADAM17-dependent c-MET-STAT3 signaling mediates resistance to MEK inhibitors in KRAS mutant colorectal cancer. | ||||||||||
| Author: | Van Schaeybroeck, Sandra|Kalimutho, Murugan|Dunne, Philip D|Carson, Robbie|Allen, Wendy|Jithesh, Puthen V|Redmond, Keara L|Sasazuki, Takehiko|Shirasawa, Senji|Blayney, Jaine|Michieli, Paolo|Fenning, Cathy|Lenz, Heinz-Josef|Lawler, Mark|Longley, Daniel B|J | ||||||||||
| PMID: | 24931611 | ||||||||||
| 14. | |||||||||||
| Journal: | Neoplasma. 2014;61(1):56-62. | ||||||||||
| Title: | INCB018424 induces apoptotic cell death through the suppression of pJAK1 in human colon cancer cells. | ||||||||||
| Author: | An, H J|Choi, E K|Kim, J S|Hong, S W|Moon, J H|Shin, J S|Ha, S H|Kim, K P|Hong, Y S|Lee, J L|Choi, E K|Lee, J S|Jin, D H|Kim, T W | ||||||||||
| PMID: | 24195509 | ||||||||||
| 15. | |||||||||||
| Journal: | Oncol Rep. 2015 Jan;33(1):185-92. | ||||||||||
| Title: | Effect of Smad3/4 on chemotherapeutic drug sensitivity in colorectal cancer cells. | ||||||||||
| Author: | Moon, Sung Ung|Kang, Mi Hyun|Sung, Ji Hea|Kim, Jin Won|Lee, Jeong Ok|Kim, Yu Jung|Lee, Keun Wook|Bang, Soo Mee|Lee, Jong Seok|Kim, Jee Hyun | ||||||||||
| PMID: | 25370208 | ||||||||||
| 16. | |||||||||||
| Journal: | DNA Cell Biol. 2015 Aug;34(8):541-9. | ||||||||||
| Title: | The Tumor Suppressive Effects of HPP1 Are Mediated Through JAK-STAT-Interferon Signaling Pathways. | ||||||||||
| Author: | Hernandez, Jonathan M|Elahi, Abul|Clark, Whalen|Humphries, Leigh Ann|Wang, Jian|Achille, Alex|Seto, Ed|Shibata, David | ||||||||||
| PMID: | 26061044 | ||||||||||
| 17. | |||||||||||
| Journal: | Curr Cancer Drug Targets. 2015;15(8):703-15. | ||||||||||
| Title: | Prognostic and Predictive Biomarkers in Colorectal Cancer. From the Preclinical Setting to Clinical Practice. | ||||||||||
| Author: | Maurel, Joan|Postigo, Antonio | ||||||||||
| PMID: | 26452385 | ||||||||||
| 18. | |||||||||||
| Journal: | Cell Metab. 2016 Sep 13;24(3):447-461. | ||||||||||
| Title: | Iron Uptake via DMT1 Integrates Cell Cycle with JAK-STAT3 Signaling to Promote Colorectal Tumorigenesis. | ||||||||||
| Author: | Xue, Xiang|Ramakrishnan, Sadeesh K|Weisz, Kevin|Triner, Daniel|Xie, Liwei|Attili, Durga|Pant, Asha|Gyorffy, Balazs|Zhan, Mingkun|Carter-Su, Christin|Hardiman, Karin M|Wang, Thomas D|Dame, Michael K|Varani, James|Brenner, Dean|Fearon, Eric R|Shah, Yatrik M | ||||||||||
| PMID: | 27546461 | ||||||||||
| 19. | |||||||||||
| Journal: | Oncogene. 2017 May 11;36(19):2655-2666. | ||||||||||
| Title: | The LIM protein AJUBA promotes colorectal cancer cell survival through suppression of JAK1/STAT1/IFIT2 network. | ||||||||||
| Author: | Jia, H|Song, L|Cong, Q|Wang, J|Xu, H|Chu, Y|Li, Q|Zhang, Y|Zou, X|Zhang, C|Chin, Y E|Zhang, X|Li, Z|Zhu, K|Wang, B|Peng, H|Hou, Z | ||||||||||
| PMID: | 27893714 | ||||||||||
| 20. | |||||||||||
| Journal: | Cancer Discov. 2017 Feb;7(2):188-201. | ||||||||||
| Title: | Primary Resistance to PD-1 Blockade Mediated by JAK1/2 Mutations. | ||||||||||
| Author: | Shin, Daniel Sanghoon|Zaretsky, Jesse M|Escuin-Ordinas, Helena|Garcia-Diaz, Angel|Hu-Lieskovan, Siwen|Kalbasi, Anusha|Grasso, Catherine S|Hugo, Willy|Sandoval, Salemiz|Torrejon, Davis Y|Palaskas, Nicolaos|Rodriguez, Gabriel Abril|Parisi, Giulia|Azhdam, Ar | ||||||||||
| PMID: | 27903500 | ||||||||||
| 21. | |||||||||||
| Journal: | Oncotarget. 2017 Jun 13;8(24):38113-38135. | ||||||||||
| Title: | Interleukin-4 and interleukin-13 increase NADPH oxidase 1-related proliferation of human colon cancer cells. | ||||||||||
| Author: | Liu, Han|Antony, Smitha|Roy, Krishnendu|Juhasz, Agnes|Wu, Yongzhong|Lu, Jiamo|Meitzler, Jennifer L|Jiang, Guojian|Polley, Eric|Doroshow, James H | ||||||||||
| PMID: | 28498822 | ||||||||||
| 22. | |||||||||||
| Journal: | Genome Med. 2017 May 24;9(1):46. | ||||||||||
| Title: | Multilevel genomics of colorectal cancers with microsatellite instability-clinical impact of JAK1 mutations and consensus molecular subtype 1. | ||||||||||
| Author: | Sveen, Anita|Johannessen, Bjarne|Tengs, Torstein|Danielsen, Stine A|Eilertsen, Ina A|Lind, Guro E|Berg, Kaja C G|Leithe, Edward|Meza-Zepeda, Leonardo A|Domingo, Enric|Myklebost, Ola|Kerr, David|Tomlinson, Ian|Nesbakken, Arild|Skotheim, Rolf I|Lothe, Ragnh | ||||||||||
| PMID: | 28539123 | ||||||||||
| 23. | |||||||||||
| Journal: | Oncotarget. 2017 Aug 16;8(43):74649-74660. | ||||||||||
| Title: | Fasting inhibits colorectal cancer growth by reducing M2 polarization of tumor-associated macrophages. | ||||||||||
| Author: | Sun, Pengfei|Wang, Huihui|He, Zhiyong|Chen, Xiangyuan|Wu, Qichao|Chen, Wankun|Sun, Zhirong|Weng, Meilin|Zhu, Minmin|Ma, Duan|Miao, Changhong | ||||||||||
| PMID: | 29088814 | ||||||||||
| 24. | |||||||||||
| Journal: | PLoS One. 2018 Apr 11;13(4):e0194098. | ||||||||||
| Title: | Germline mutations in candidate predisposition genes in individuals with cutaneous melanoma and at least two independent additional primary cancers. | ||||||||||
| Author: | Pritchard, Antonia L|Johansson, Peter A|Nathan, Vaishnavi|Howlie, Madeleine|Symmons, Judith|Palmer, Jane M|Hayward, Nicholas K | ||||||||||
| PMID: | 29641532 | ||||||||||
| 25. | |||||||||||
| Journal: | Technol Cancer Res Treat. 2018 Jan 1;17:1533034618775509. | ||||||||||
| Title: | MiR-199a-5p Inhibits the Growth and Metastasis of Colorectal Cancer Cells by Targeting ROCK1. | ||||||||||
| Author: | Zhu, Qian Dong|Zhou, Qing Qing|Dong, Lemei|Huang, Zhiming|Wu, Fang|Deng, Xia | ||||||||||
| PMID: | 29807462 | ||||||||||
| 26. | |||||||||||
| Journal: | Cancer Med. 2018 Aug 19. | ||||||||||
| Title: | Randomized, double-blind, phase two study of ruxolitinib plus regorafenib in patients with relapsed/refractory metastatic colorectal cancer. | ||||||||||
| Author: | Fogelman, David|Cubillo, Antonio|Garcia-Alfonso, Pilar|Miron, Maria Luisa Limon|Nemunaitis, John|Flora, Daniel|Borg, Christophe|Mineur, Laurent|Vieitez, Jose M|Cohn, Allen|Saylors, Gene|Assad, Albert|Switzky, Julie|Zhou, Li|Bendell, Johanna | ||||||||||
| PMID: | 30123970 | ||||||||||