Primary Site >> Pancreatic Cancer

Gene >> ITK

Journal: Clin Cancer Res. 2004 Jun 15;10(12 Pt 1):4125-33.
Title: N-cadherin expression and epithelial-mesenchymal transition in pancreatic carcinoma.
Author: Nakajima, Sanae|Doi, Ryuichiro|Toyoda, Eiji|Tsuji, Shoichiro|Wada, Michihiko|Koizumi, Masayuki|Tulachan, Sidhartha S|Ito, Daisuke|Kami, Kazuhiro|Mori, Tomohiko|Kawaguchi, Yoshiya|Fujimoto, Koji|Hosotani, Ryo|Imamura, Masayuki
PMID: 15217949
Journal: Genes Dev. 2006 Nov 15;20(22):3130-46.
Title: Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer.
Author: Bardeesy, Nabeel|Cheng, Kuang-Hung|Berger, Justin H|Chu, Gerald C|Pahler, Jessica|Olson, Peter|Hezel, Aram F|Horner, James|Lauwers, Gregory Y|Hanahan, Douglas|DePinho, Ronald A
PMID: 17114584
Journal: J Huazhong Univ Sci Technolog Med Sci. 2006;26(6):700-2.
Title: Implication of EMT induced by TGF-beta1 in pancreatic cancer.
Author: Yin, Tao|Wang, Chunyou|Liu, Tao|Zhao, Gang|Zhou, Feng
PMID: 17357493
Journal: Cancer. 2007 Mar 15;109(6):1030-9.
Title: Tyrosine kinase receptor RON in human pancreatic cancer: expression, function, and validation as a target.
Author: Camp, E Ramsay|Yang, Anthony|Gray, Mike J|Fan, Fan|Hamilton, Stanley R|Evans, Douglas B|Hooper, Andrea T|Pereira, Daniel S|Hicklin, Daniel J|Ellis, Lee M
PMID: 17311308
Journal: Ann Surg Oncol. 2007 Dec;14(12):3629-37. Epub 2007 Oct 2.
Title: Development and characterization of gemcitabine-resistant pancreatic tumor cells.
Author: Shah, Ami N|Summy, Justin M|Zhang, Jing|Park, Serk In|Parikh, Nila U|Gallick, Gary E
PMID: 17909916
Journal: Carcinogenesis. 2008 Feb;29(2):252-62.
Title: Loss of type III transforming growth factor beta receptor expression increases motility and invasiveness associated with epithelial to mesenchymal transition during pancreatic cancer progression.
Author: Gordon, Kelly J|Dong, Mei|Chislock, Elizabeth M|Fields, Timothy A|Blobe, Gerard C
PMID: 17999987
Journal: J Cell Biol. 2008 Mar 24;180(6):1277-89.
Title: Collagen I-mediated up-regulation of N-cadherin requires cooperative signals from integrins and discoidin domain receptor 1.
Author: Shintani, Yasushi|Fukumoto, Yuri|Chaika, Nina|Svoboda, Robert|Wheelock, Margaret J|Johnson, Keith R
PMID: 18362184
Journal: Nihon Shokakibyo Gakkai Zasshi. 2008 Nov;105(11):1656-65.
Title: [Two cases of anaplastic carcinoma of the pancreas in terms of the diversity of carcinoma cells (epithelial-mesenchymal transition; EMT)].
Author: Okamoto, Masaru|Kitajima, Satoshi|Negishi, Ryuujirou|Maehata, Tadateru|Kouro, Tsuyoshi|Yamauchi, Shunichi|Takahashi, Hideaki|Katakura, Yoshiki|Watanabe, Yoshiyuki|Abiko, Ryuichi|Nakaya, Shinichi|Inaba, Hiroyuki|Takano, Toshifumi|Suzuki, Michihiro|Itoh, Fu
PMID: 18987452
Journal: Int J Oncol. 2009 Jun;34(6):1737-42.
Title: Integrative genomic analyses of ZEB2: Transcriptional regulation of ZEB2 based on SMADs, ETS1, HIF1alpha, POU/OCT, and NF-kappaB.
Author: Katoh, Masuko|Katoh, Masaru
PMID: 19424592
Journal: Int J Oncol. 2009 Jul;35(1):187-92.
Title: Integrative genomic analyses on GLI1: positive regulation of GLI1 by Hedgehog-GLI, TGFbeta-Smads, and RTK-PI3K-AKT signals, and negative regulation of GLI1 by Notch-CSL-HES/HEY, and GPCR-Gs-PKA signals.
Author: Katoh, Yuriko|Katoh, Masaru
PMID: 19513567
Journal: Cancer Res. 2009 Aug 15;69(16):6704-12.
Title: Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-to-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells.
Author: Li, Yiwei|VandenBoom, Timothy G 2nd|Kong, Dejuan|Wang, Zhiwei|Ali, Shadan|Philip, Philip A|Sarkar, Fazlul H
PMID: 19654291
Journal: Cancer Biol Ther. 2009 Nov;8(21):2013-24.
Title: A resource for analysis of microRNA expression and function in pancreatic ductal adenocarcinoma cells.
Author: Kent, Oliver A|Mullendore, Michael|Wentzel, Eric A|Lopez-Romero, Pedro|Tan, Aik Choon|Alvarez, Hector|West, Kristen|Ochs, Michael F|Hidalgo, Manuel|Arking, Dan E|Maitra, Anirban|Mendell, Joshua T
PMID: 20037478
Journal: World J Stem Cells. 2009 Dec 31;1(1):8-10.
Title: Tumor initiating cells in pancreatic cancer: A critical view.
Author: Kong, Bo|Michalski, Christoph W|Kleeff, Jorg
PMID: 21607102
Journal: Cancer Res. 2010 Mar 1;70(5):2115-25.
Title: Loss of FOXA1/2 is essential for the epithelial-to-mesenchymal transition in pancreatic cancer.
Author: Song, Yan|Washington, M Kay|Crawford, Howard C
PMID: 20160041
Journal: Exp Mol Pathol. 2010 Oct;89(2):149-57.
Title: SNAIL induces epithelial-to-mesenchymal transition in a human pancreatic cancer cell line (BxPC3) and promotes distant metastasis and invasiveness in vivo.
Author: Nishioka, Ryohei|Itoh, Shunji|Gui, Ting|Gai, Zhibo|Oikawa, Kosuke|Kawai, Manabu|Tani, Masaji|Yamaue, Hiroki|Muragaki, Yasuteru
PMID: 20576520
Journal: Oncogene. 2010 Sep 16;29(37):5146-58.
Title: AZGP1 is a tumor suppressor in pancreatic cancer inducing mesenchymal-to-epithelial transdifferentiation by inhibiting TGF-beta-mediated ERK signaling.
Author: Kong, B|Michalski, C W|Hong, X|Valkovskaya, N|Rieder, S|Abiatari, I|Streit, S|Erkan, M|Esposito, I|Friess, H|Kleeff, J
PMID: 20581862
Journal: Mol Cancer. 2011 Jan 13;10:8.
Title: Cyr61/CCN1 signaling is critical for epithelial-mesenchymal transition and stemness and promotes pancreatic carcinogenesis.
Author: Haque, Inamul|Mehta, Smita|Majumder, Monami|Dhar, Kakali|De, Archana|McGregor, Douglas|Van Veldhuizen, Peter J|Banerjee, Sushanta K|Banerjee, Snigdha
PMID: 21232118
Journal: Biochem J. 2011 Jun 1;436(2):271-82.
Title: Silencing of hHS6ST2 inhibits progression of pancreatic cancer through inhibition of Notch signalling.
Author: Song, Kai|Li, Qin|Peng, Yong-Bo|Li, Jie|Ding, Kan|Chen, Li-Juan|Shao, Cheng-Hao|Zhang, Li-Jun|Li, Ping
PMID: 21443520
Journal: J Cell Biochem. 2011 Sep;112(9):2296-306.
Title: Over-expression of FoxM1 leads to epithelial-mesenchymal transition and cancer stem cell phenotype in pancreatic cancer cells.
Author: Bao, Bin|Wang, Zhiwei|Ali, Shadan|Kong, Dejuan|Banerjee, Sanjeev|Ahmad, Aamir|Li, Yiwei|Azmi, Asfar S|Miele, Lucio|Sarkar, Fazlul H
PMID: 21503965
Journal: Clin Cancer Res. 2011 Sep 1;17(17):5822-32.
Title: Anti-VEGF treatment-resistant pancreatic cancers secrete proinflammatory factors that contribute to malignant progression by inducing an EMT cell phenotype.
Author: Carbone, Carmine|Moccia, Tania|Zhu, Cihui|Paradiso, Genni|Budillon, Alfredo|Chiao, Paul J|Abbruzzese, James L|Melisi, Davide
PMID: 21737511
Journal: Cancer Res. 2012 Jan 1;72(1):88-99.
Title: GLI1 inhibition promotes epithelial-to-mesenchymal transition in pancreatic cancer cells.
Author: Joost, Simon|Almada, Luciana L|Rohnalter, Verena|Holz, Philipp S|Vrabel, Anne M|Fernandez-Barrena, Maite G|McWilliams, Robert R|Krause, Michael|Fernandez-Zapico, Martin E|Lauth, Matthias
PMID: 22086851
Journal: J Surg Res. 2012 Mar;173(1):105-12.
Title: Contribution of epithelial-to-mesenchymal transition and cancer stem cells to pancreatic cancer progression.
Author: Krantz, Seth B|Shields, Mario A|Dangi-Garimella, Surabhi|Munshi, Hidayatullah G|Bentrem, David J
PMID: 22099597
Journal: Cell. 2012 Jan 20;148(1-2):349-61.
Title: EMT and dissemination precede pancreatic tumor formation.
Author: Rhim, Andrew D|Mirek, Emily T|Aiello, Nicole M|Maitra, Anirban|Bailey, Jennifer M|McAllister, Florencia|Reichert, Maximilian|Beatty, Gregory L|Rustgi, Anil K|Vonderheide, Robert H|Leach, Steven D|Stanger, Ben Z
PMID: 22265420
Journal: Clin Cancer Res. 2012 May 15;18(10):2838-49.
Title: Molecular profiling of pancreatic neuroendocrine tumors in sporadic and Von Hippel-Lindau patients.
Author: Speisky, Daniela|Duces, Aurelie|Bieche, Ivan|Rebours, Vinciane|Hammel, Pascal|Sauvanet, Alain|Richard, Stephane|Bedossa, Pierre|Vidaud, Michel|Murat, Arnaud|Niccoli, Patricia|Scoazec, Jean-Yves|Ruszniewski, Philippe|Couvelard, Anne
PMID: 22461457
Journal: PLoS One. 2012;7(4):e33214.
Title: Inhibition of mesothelin as a novel strategy for targeting cancer cells.
Author: Wang, Kun|Bodempudi, Vidya|Liu, Zhengian|Borrego-Diaz, Emma|Yamoutpoor, Farnaz|Meyer, Anna|Woo, Richard A|Pan, Weihong|Dudek, Arkadiusz Z|Olyaee, Mojtaba S|Esfandyari, Tuba|Farassati, Faris
PMID: 22485139
Journal: J Cell Commun Signal. 2012 Jun;6(2):63-71.
Title: CCN5/WISP-2: A micromanager of breast cancer progression.
Author: Banerjee, Sushanta K|Banerjee, Snigdha
PMID: 22487979
Journal: Tumour Biol. 2012 Oct;33(5):1527-34.
Title: JDP2 inhibits the epithelial-to-mesenchymal transition in pancreatic cancer BxPC3 cells.
Author: Liu, Zhe|Du, Ruixia|Long, Jin|Dong, Anbing|Fan, Jianpeng|Guo, Kejian|Xu, Yuanhong
PMID: 22535371
Journal: Am J Pathol. 2012 Jun;180(6):2188-200.
Title: Role of Cripto-1 during epithelial-to-mesenchymal transition in development and cancer.
Author: Rangel, Maria C|Karasawa, Hideaki|Castro, Nadia P|Nagaoka, Tadahiro|Salomon, David S|Bianco, Caterina
PMID: 22542493
Journal: Front Biosci (Landmark Ed). 2012 Jun 1;17:2541-9.
Title: BMP2 induces PANC-1 cell invasion by MMP-2 overexpression through ROS and ERK.
Author: Liu, Jun|Ben, Qi-Wen|Yao, Wei-Yan|Zhang, Jian-Jun|Chen, Da-Fan|He, Xiang-Yi|Li, Lei|Yuan, Yao-Zong
PMID: 22652796
Journal: Anticancer Drugs. 2012 Oct;23(9):935-46.
Title: Pancreatic cancer cells retain the epithelial-related phenotype and modify mitotic spindle microtubules after the administration of ukrain in vitro.
Author: Gagliano, Nicoletta|Volpari, Tatiana|Clerici, Marco|Pettinari, Letizia|Barajon, Isabella|Portinaro, Nicola|Colombo, Graziano|Milzani, Aldo|Dalle-Donne, Isabella|Martinelli, Carla
PMID: 22700003
Journal: Curr Opin Gastroenterol. 2012 Sep;28(5):516-22.
Title: Emerging frontiers in pancreatic cancer research: elaboration of key genes, cells and the extracellular milieu.
Author: Kumar-Sinha, Chandan|Wei, Iris|Simeone, Diane M
PMID: 22759592
Journal: Cancer Res. 2012 Jul 15;72(14):3702-3; author reply 3704-5.
Title: GLI1 modulates EMT in pancreatic cancer--letter.
Author: Inaguma, Shingo|Kasai, Kenji|Hashimoto, Mitsuyoshi|Ikeda, Hiroshi
PMID: 22761339
Journal: Oncol Lett. 2012 Jun;3(6):1186-1190.
Title: Neoadjuvant chemotherapy with gemcitabine for pancreatic cancer increases in situ expression of the apoptosis marker M30 and stem cell marker CD44.
Author: Tajima, Hidehiro|Ohta, Tetsuo|Kitagawa, Hirohisa|Okamoto, Koichi|Sakai, Seisho|Kinoshita, Jun|Makino, Isamu|Furukawa, Hiroyuki|Hayashi, Hironori|Nakamura, Keishi|Oyama, Katsunobu|Inokuchi, Masafumi|Nakagawara, Hisatoshi|Fujita, Hideto|Takamura, Hiroyuki|N
PMID: 22783415
Journal: Clin Cancer Res. 2012 Sep 15;18(18):5031-42.
Title: Apricoxib, a novel inhibitor of COX-2, markedly improves standard therapy response in molecularly defined models of pancreatic cancer.
Author: Kirane, Amanda|Toombs, Jason E|Ostapoff, Katherine|Carbon, Juliet G|Zaknoen, Sara|Braunfeld, Jordan|Schwarz, Roderich E|Burrows, Francis J|Brekken, Rolf A
PMID: 22829202
Journal: J Exp Clin Cancer Res. 2012 Aug 27;31:68.
Title: Molecular markers associated with outcome and metastasis in human pancreatic cancer.
Author: Van den Broeck, Anke|Vankelecom, Hugo|Van Eijsden, Rudy|Govaere, Olivier|Topal, Baki
PMID: 22925330
Journal: Anticancer Res. 2012 Sep;32(9):3847-53.
Title: Chemoresistance is associated with cancer stem cell-like properties and epithelial-to-mesenchymal transition in pancreatic cancer cells.
Author: Izumiya, Motoko|Kabashima, Ayano|Higuchi, Hajime|Igarashi, Toru|Sakai, Gen|Iizuka, Hideko|Nakamura, Shoko|Adachi, Masayuki|Hamamoto, Yasuo|Funakoshi, Shinsuke|Takaishi, Hiromasa|Hibi, Toshifumi
PMID: 22993328
Journal: J Biol Chem. 2012 Nov 9;287(46):38569-79.
Title: The matricellular protein CCN1/Cyr61 is a critical regulator of Sonic Hedgehog in pancreatic carcinogenesis.
Author: Haque, Inamul|De, Archana|Majumder, Monami|Mehta, Smita|McGregor, Douglas|Banerjee, Sushanta K|Van Veldhuizen, Peter|Banerjee, Snigdha
PMID: 23027863
Journal: Pancreat Disord Ther. 2012 Sep 29;2(3).
Title: The Role of EMT in Pancreatic Cancer Progression.
Author: Wu, Qiong|Miele, Lucio|Sarkar, Fazlul H|Wang, Zhiwei
PMID: 23145368
Journal: Clin Dev Immunol. 2012;2012:720768.
Title: Epithelial-to-mesenchymal transition in pancreatic ductal adenocarcinoma and pancreatic tumor cell lines: the role of neutrophils and neutrophil-derived elastase.
Author: Grosse-Steffen, Thomas|Giese, Thomas|Giese, Nathalia|Longerich, Thomas|Schirmacher, Peter|Hansch, G Maria|Gaida, Matthias M
PMID: 23227088
Journal: PLoS One. 2012;7(12):e50165.
Title: Hypoxia-induced aggressiveness of pancreatic cancer cells is due to increased expression of VEGF, IL-6 and miR-21, which can be attenuated by CDF treatment.
Author: Bao, Bin|Ali, Shadan|Ahmad, Aamir|Azmi, Asfar S|Li, Yiwei|Banerjee, Sanjeev|Kong, Dejuan|Sethi, Seema|Aboukameel, Amro|Padhye, Subhash B|Sarkar, Fazlul H
PMID: 23272057
Journal: Cancers (Basel). 2012 Oct 12;4(4):989-1035.
Title: Cancer Stem Cells, EMT, and Developmental Pathway Activation in Pancreatic Tumors.
Author: Hindriksen, Sanne|Bijlsma, Maarten F
PMID: 24213498
Journal: Int J Cancer. 2013 Feb 15;132(4):785-94.
Title: Macrophage migration inhibitory factor induces epithelial to mesenchymal transition, enhances tumor aggressiveness and predicts clinical outcome in resected pancreatic ductal adenocarcinoma.
Author: Funamizu, Naotake|Hu, Chaoxin|Lacy, Curtis|Schetter, Aaron|Zhang, Geng|He, Peijun|Gaedcke, Jochen|Ghadimi, Michael B|Ried, Thomas|Yfantis, Harris G|Lee, Dong H|Subleski, Jeffrey|Chan, Tim|Weiss, Jonathan M|Back, Timothy C|Yanaga, Katsuhiko|Hanna, Nader|Al
PMID: 22821831
Journal: Oncogene. 2013 Aug 22;32(34):3980-91.
Title: Deguelin suppresses pancreatic tumor growth and metastasis by inhibiting epithelial-to-mesenchymal transition in an orthotopic model.
Author: Boreddy, S R|Srivastava, S K
PMID: 22986522
Journal: Mol Cell Biochem. 2013 Jan;373(1-2):217-27.
Title: Sulforaphane regulates self-renewal of pancreatic cancer stem cells through the modulation of Sonic hedgehog-GLI pathway.
Author: Li, Shih-Hui|Fu, Junsheng|Watkins, Dara Nall|Srivastava, Rakesh K|Shankar, Sharmila
PMID: 23129257
Journal: Cancer Lett. 2013 Mar 1;330(1):11-21.
Title: Delta like ligand 4 induces impaired chemo-drug delivery and enhanced chemoresistance in pancreatic cancer.
Author: Kang, Muxing|Jiang, Biao|Xu, Bin|Lu, Wenjie|Guo, Qingqu|Xie, Qiuping|Zhang, Bo|Dong, Xin|Chen, Daniel|Wu, Yulian
PMID: 23200678
Journal: World J Surg. 2013 Aug;37(8):1892-900.
Title: Lipocalin-2 is associated with a good prognosis and reversing epithelial-to-mesenchymal transition in pancreatic cancer.
Author: Xu, Bin|Jin, Da-Yong|Lou, Wen-Hui|Wang, Dan-Song
PMID: 23539193
Journal: Pancreatology. 2013 Mar-Apr;13(2):114-7.
Title: Epithelial to mesenchymal transition and the generation of stem-like cells in pancreatic cancer.
Author: Rhim, Andrew D
PMID: 23561968
Journal: Mol Cancer Ther. 2013 Jun;12(6):992-1001.
Title: BIBF 1120 (nintedanib), a triple angiokinase inhibitor, induces hypoxia but not EMT and blocks progression of preclinical models of lung and pancreatic cancer.
Author: Kutluk Cenik, Bercin|Ostapoff, Katherine T|Gerber, David E|Brekken, Rolf A
PMID: 23729403
Journal: Mol Cancer Res. 2013 Sep;11(9):1078-87.
Title: Snail cooperates with KrasG12D to promote pancreatic fibrosis.
Author: Shields, Mario A|Ebine, Kazumi|Sahai, Vaibhav|Kumar, Krishan|Siddiqui, Kulsumjehan|Hwang, Rosa F|Grippo, Paul J|Munshi, Hidayatullah G
PMID: 23761168
Journal: Pancreatology. 2013 Jul-Aug;13(4):384-92.
Title: WNT5A/JNK signaling regulates pancreatic cancer cells migration by Phosphorylating Paxillin.
Author: Wei, Wei|Li, Hongyue|Li, Na|Sun, Huihui|Li, Qiang|Shen, Xiaohong
PMID: 23890137
Journal: Oncogenesis. 2013 Aug 5;2:e61.
Title: SOX2 promotes dedifferentiation and imparts stem cell-like features to pancreatic cancer cells.
Author: Herreros-Villanueva, M|Zhang, J-S|Koenig, A|Abel, E V|Smyrk, T C|Bamlet, W R|de Narvajas, A A-M|Gomez, T S|Simeone, D M|Bujanda, L|Billadeau, D D
PMID: 23917223
Journal: PLoS One. 2013 Jul 29;8(7):e70334.
Title: Targeting cancer-related inflammation: Chinese herbal medicine inhibits epithelial-to-mesenchymal transition in pancreatic cancer.
Author: Zhang, Juan|Wang, Peng|Ouyang, Huaqiang|Yin, Jianhua|Liu, Aihua|Ma, Chunzheng|Liu, Luming
PMID: 23922983
Journal: Curr Med Chem. 2013;20(33):4185-4194.
Title: Resveratrol inhibits the epithelial-mesenchymal transition of pancreatic cancer cells via suppression of the PI-3K/Akt/NF-kappaB pathway.
Author: Li, Wei|Ma, Jiguang|Ma, Qingyong|Li, Bin|Han, Liang|Liu, Jiangbo|Xu, Qinhong|Duan, Wanxing|Yu, Shuo|Wang, Fengfei|Wu, Erxi
PMID: 23992306
Journal: Surgery. 2013 Nov;154(5):946-54.
Title: Epithelial-to-mesenchymal transition predicts prognosis of pancreatic cancer.
Author: Yamada, Suguru|Fuchs, Bryan C|Fujii, Tsutomu|Shimoyama, Yoshie|Sugimoto, Hiroyuki|Nomoto, Shuji|Takeda, Shin|Tanabe, Kenneth K|Kodera, Yasuhiro|Nakao, Akimasa
PMID: 24075276
Journal: BMC Cancer. 2013 Oct 25;13:496.
Title: Upregulation of Wnt5a promotes epithelial-to-mesenchymal transition and metastasis of pancreatic cancer cells.
Author: Bo, Haiji|Zhang, Shuhui|Gao, Li|Chen, Ying|Zhang, Jing|Chang, Xuejiao|Zhu, Minghua
PMID: 24156409
Journal: PLoS One. 2013 Oct 23;8(10):e78327.
Title: Overexpression of COL11A1 by cancer-associated fibroblasts: clinical relevance of a stromal marker in pancreatic cancer.
Author: Garcia-Pravia, Carmen|Galvan, Jose A|Gutierrez-Corral, Natalia|Solar-Garcia, Lorena|Garcia-Perez, Eva|Garcia-Ocana, Marcos|Del Amo-Iribarren, Jokin|Menendez-Rodriguez, Primitiva|Garcia-Garcia, Juan|de Los Toyos, Juan R|Simon-Buela, Laureano|Barneo, Luis
PMID: 24194920
Journal: PLoS One. 2013 Oct 25;8(10):e73356.
Title: MicroRNA-200c modulates the expression of MUC4 and MUC16 by directly targeting their coding sequences in human pancreatic cancer.
Author: Radhakrishnan, Prakash|Mohr, Ashley M|Grandgenett, Paul M|Steele, Maria M|Batra, Surinder K|Hollingsworth, Michael A
PMID: 24204560
Journal: Toxicol Lett. 2014 Jan 3;224(1):7-15.
Title: Par-4 downregulation confers cisplatin resistance in pancreatic cancer cells via PI3K/Akt pathway-dependent EMT.
Author: Tan, Jiaxin|You, Yu|Xu, Tubin|Yu, Peng|Wu, Dingguo|Deng, Hao|Zhang, Yujun|Bie, Ping
PMID: 24144893
Journal: J Clin Invest. 2014 Jan;124(1):338-52.
Title: Pancreatic cancer-associated retinoblastoma 1 dysfunction enables TGF-beta to promote proliferation.
Author: Gore, A Jesse|Deitz, Samantha L|Palam, Lakshmi Reddy|Craven, Kelly E|Korc, Murray
PMID: 24334458
Journal: Clin Cancer Res. 2014 Mar 15;20(6):1477-88.
Title: FOXM1c promotes pancreatic cancer epithelial-to-mesenchymal transition and metastasis via upregulation of expression of the urokinase plasminogen activator system.
Author: Huang, Chen|Xie, Dacheng|Cui, Jiujie|Li, Qi|Gao, Yong|Xie, Keping
PMID: 24452790
Journal: PLoS One. 2014 Jan 29;9(1):e87409.
Title: Snail contributes to the maintenance of stem cell-like phenotype cells in human pancreatic cancer.
Author: Zhou, Wei|Lv, Ran|Qi, Weilin|Wu, Di|Xu, Yunyun|Liu, Wei|Mou, Yiping|Wang, Liewei
PMID: 24489910
Journal: BMC Cancer. 2014 Feb 12;14:85.
Title: MiR-200a inhibits epithelial-mesenchymal transition of pancreatic cancer stem cell.
Author: Lu, Yuhua|Lu, Jingjing|Li, Xiaohong|Zhu, Hui|Fan, Xiangjun|Zhu, Shajun|Wang, Yao|Guo, Qingsong|Wang, Lei|Huang, Yan|Zhu, Mingyan|Wang, Zhiwei
PMID: 24521357
Journal: Oncol Rep. 2014 Apr;31(4):1891-8.
Title: Effects of the HIF-1alpha and NF-kappaB loop on epithelial-mesenchymal transition and chemoresistance induced by hypoxia in pancreatic cancer cells.
Author: Cheng, Zhuo-Xin|Wang, Da-Wei|Liu, Tao|Liu, Wei-Xin|Xia, Wei-Bin|Xu, Jian|Zhang, Ying-Hai|Qu, Yi-Kun|Guo, Lin-Qi|Ding, Long|Hou, Jie|Zhong, Zhao-Hua
PMID: 24535079
Journal: Biomed Res Int. 2014;2014:760303.
Title: The low chamber pancreatic cancer cells had stem-like characteristics in modified transwell system: is it a novel method to identify and enrich cancer stem-like cells?
Author: Wang, Dongqing|Zhu, Haitao|Liu, Yanfang|Liu, Qing|Xie, Xiaodong|Zhou, Yuepeng|Zhang, Lirong|Zhu, Yan|Zhang, Zhijian|Su, Zhaoliang
PMID: 24689055
Journal: PLoS One. 2014 Apr 2;9(4):e92161.
Title: Embelin suppresses growth of human pancreatic cancer xenografts, and pancreatic cancer cells isolated from KrasG12D mice by inhibiting Akt and Sonic hedgehog pathways.
Author: Huang, Minzhao|Tang, Su-Ni|Upadhyay, Ghanshyam|Marsh, Justin L|Jackman, Christopher P|Shankar, Sharmila|Srivastava, Rakesh K
PMID: 24694877
Journal: PLoS One. 2014 May 8;9(5):e97016.
Title: Targeting insulin-like growth factor 1 receptor inhibits pancreatic cancer growth and metastasis.
Author: Subramani, Ramadevi|Lopez-Valdez, Rebecca|Arumugam, Arunkumar|Nandy, Sushmita|Boopalan, Thiyagarajan|Lakshmanaswamy, Rajkumar
PMID: 24809702
Journal: Asian Pac J Cancer Prev. 2014;15(8):3687-90.
Title: How to explain the contradiction of microRNA 200c expression and survival in solid tumors? A meta-analysis.
Author: Wang, Hui-Yu|Shen, Jie|Jiang, Chun-Ping|Liu, Bao-Rui
PMID: 24870778
Journal: Cancer Lett. 2014 Aug 28;351(1):151-61.
Title: XMD8-92 inhibits pancreatic tumor xenograft growth via a DCLK1-dependent mechanism.
Author: Sureban, Sripathi M|May, Randal|Weygant, Nathaniel|Qu, Dongfeng|Chandrakesan, Parthasarathy|Bannerman-Menson, Eddie|Ali, Naushad|Pantazis, Panayotis|Westphalen, Christoph B|Wang, Timothy C|Houchen, Courtney W
PMID: 24880079
Journal: Oncol Rep. 2014 Sep;32(3):935-42.
Title: Upregulation of autophagy by hypoxia-inducible factor-1alpha promotes EMT and metastatic ability of CD133+ pancreatic cancer stem-like cells during intermittent hypoxia.
Author: Zhu, Haitao|Wang, Dongqing|Zhang, Lirong|Xie, Xiaodong|Wu, Yingying|Liu, Yanfang|Shao, Genbao|Su, Zhaoliang
PMID: 24994549
Journal: Proc Natl Acad Sci U S A. 2014 Sep 9;111(36):13235-40.
Title: Surprisal analysis characterizes the free energy time course of cancer cells undergoing epithelial-to-mesenchymal transition.
Author: Zadran, Sohila|Arumugam, Rameshkumar|Herschman, Harvey|Phelps, Michael E|Levine, R D
PMID: 25157127
Journal: Oncotarget. 2014 Oct 30;5(20):9546-63.
Title: AXL kinase as a novel target for cancer therapy.
Author: Wu, Xiaoliang|Liu, Xuewen|Koul, Sanjay|Lee, Chang Youl|Zhang, Zhenfeng|Halmos, Balazs
PMID: 25337673
Journal: Cancer Lett. 2015 Jan 28;356(2 Pt B):613-27.
Title: Mutated K-ras activates CDK8 to stimulate the epithelial-to-mesenchymal transition in pancreatic cancer in part via the Wnt/beta-catenin signaling pathway.
Author: Xu, Wei|Wang, Ziwei|Zhang, Wei|Qian, Kun|Li, Hui|Kong, Dequan|Li, Yuqiang|Tang, Yucheng
PMID: 25305448
Journal: Br J Cancer. 2015 Jan 6;112(1):131-9.
Title: MiR-23a/-24-induced gene silencing results in mesothelial cell integration of pancreatic cancer.
Author: Listing, H|Mardin, W A|Wohlfromm, S|Mees, S T|Haier, J
PMID: 25422915
Journal: Curr Pharm Des. 2015;21(10):1262-7.
Title: Vitamin D receptor signaling and pancreatic cancer cell EMT.
Author: Li, Zhiwei|Guo, Junli|Xie, Keping|Zheng, Shaojiang
PMID: 25506892
Journal: Drug Des Devel Ther. 2015 Jan 17;9:575-601.
Title: Alisertib induces cell cycle arrest and autophagy and suppresses epithelial-to-mesenchymal transition involving PI3K/Akt/mTOR and sirtuin 1-mediated signaling pathways in human pancreatic cancer cells.
Author: Wang, Feng|Li, Hai|Yan, Xiao-Gang|Zhou, Zhi-Wei|Yi, Zhi-Gang|He, Zhi-Xu|Pan, Shu-Ting|Yang, Yin-Xue|Wang, Zuo-Zheng|Zhang, Xueji|Yang, Tianxing|Qiu, Jia-Xuan|Zhou, Shu-Feng
PMID: 25632225
Journal: Oncotarget. 2015 Jan 30;6(3):1740-9.
Title: Down-regulation of miR-223 reverses epithelial-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells.
Author: Ma, Jia|Fang, Binbin|Zeng, Fanpeng|Ma, Cong|Pang, Haijie|Cheng, Long|Shi, Ying|Wang, Hui|Yin, Bin|Xia, Jun|Wang, Zhiwei
PMID: 25638153
Journal: PLoS One. 2015 Apr 10;10(4):e0123684.
Title: Slug-dependent upregulation of L1CAM is responsible for the increased invasion potential of pancreatic cancer cells following long-term 5-FU treatment.
Author: Lund, Kaja|Dembinski, Jennifer L|Solberg, Nina|Urbanucci, Alfonso|Mills, Ian G|Krauss, Stefan
PMID: 25860483
Journal: World J Clin Cases. 2015 May 16;3(5):393-404.
Title: Epithelial-mesenchymal, mesenchymal-epithelial, and endothelial-mesenchymal transitions in malignant tumors: An update.
Author: Gurzu, Simona|Turdean, Sabin|Kovecsi, Attila|Contac, Anca Otilia|Jung, Ioan
PMID: 25984514
Journal: Cancer Lett. 2015 Sep 28;366(1):61-70.
Title: ROBO3 promotes growth and metastasis of pancreatic carcinoma.
Author: Han, Shilong|Cao, Chuanwu|Tang, Tao|Lu, Chenhui|Xu, Jichong|Wang, Shi|Xue, Lei|Zhang, Xiaoping|Li, Maoquan
PMID: 26070964
Journal: Cell Death Dis. 2015 Jun 25;6:e1795.
Title: Zidovudine, an anti-viral drug, resensitizes gemcitabine-resistant pancreatic cancer cells to gemcitabine by inhibition of the Akt-GSK3beta-Snail pathway.
Author: Namba, T|Kodama, R|Moritomo, S|Hoshino, T|Mizushima, T
PMID: 26111057
Journal: Tumour Biol. 2015 Dec;36(12):9395-403.
Title: miR-33a suppresses the nuclear translocation of beta-catenin to enhance gemcitabine sensitivity in human pancreatic cancer cells.
Author: Liang, Chen|Wang, Zhen|Li, Ying-Yi|Yu, Bao-Hua|Zhang, Fei|Li, Hong-Yu
PMID: 26113407
Journal: Pancreas. 2015 Aug;44(6):882-7.
Title: Characterization of Mouse Models of Early Pancreatic Lesions Induced by Alcohol and Chronic Pancreatitis.
Author: Xu, Shiping|Chheda, Chintan|Ouhaddi, Yassine|Benhaddou, Hajar|Bourhim, Mouloud|Grippo, Paul J|Principe, Daniel R|Mascarinas, Emman|DeCant, Brian|Tsukamoto, Hidekazu|Pandol, Stephen J|Edderkaoui, Mouad
PMID: 26166469
Journal: Nat Commun. 2015 Jul 29;6:7677.
Title: Loss of ATM accelerates pancreatic cancer formation and epithelial-mesenchymal transition.
Author: Russell, Ronan|Perkhofer, Lukas|Liebau, Stefan|Lin, Qiong|Lechel, Andre|Feld, Fenja M|Hessmann, Elisabeth|Gaedcke, Jochen|Guthle, Melanie|Zenke, Martin|Hartmann, Daniel|von Figura, Guido|Weissinger, Stephanie E|Rudolph, Karl-Lenhard|Moller, Peter|Lennerz,
PMID: 26220524
Journal: Stem Cell Res Ther. 2015 Sep 22;6:182.
Title: Polyphenols from marine brown algae target radiotherapy-coordinated EMT and stemness-maintenance in residual pancreatic cancer.
Author: Aravindan, Sheeja|Ramraj, Satish Kumar|Somasundaram, Somasundaram T|Herman, Terence S|Aravindan, Natarajan
PMID: 26395574
Journal: Oncotarget. 2015 Oct 13;6(31):32039-60.
Title: PI3K/AKT/mTOR and sonic hedgehog pathways cooperate together to inhibit human pancreatic cancer stem cell characteristics and tumor growth.
Author: Sharma, Narinder|Nanta, Rajesh|Sharma, Jay|Gunewardena, Sumedha|Singh, Karan P|Shankar, Sharmila|Srivastava, Rakesh K
PMID: 26451606
Journal: Nature. 2015 Nov 26;527(7579):525-530.
Title: Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer.
Author: Zheng, Xiaofeng|Carstens, Julienne L|Kim, Jiha|Scheible, Matthew|Kaye, Judith|Sugimoto, Hikaru|Wu, Chia-Chin|LeBleu, Valerie S|Kalluri, Raghu
PMID: 26560028
Journal: PLoS One. 2015 Dec 7;10(12):e0141392.
Title: Metformin Reduces Desmoplasia in Pancreatic Cancer by Reprogramming Stellate Cells and Tumor-Associated Macrophages.
Author: Incio, Joao|Suboj, Priya|Chin, Shan M|Vardam-Kaur, Trupti|Liu, Hao|Hato, Tai|Babykutty, Suboj|Chen, Ivy|Deshpande, Vikram|Jain, Rakesh K|Fukumura, Dai
PMID: 26641266
Journal: Int J Clin Exp Pathol. 2015 Nov 1;8(11):14005-12. eCollection 2015.
Title: Knockdown of PFTK1 inhibits tumor cell proliferation, invasion and epithelial-to-mesenchymal transition in pancreatic cancer.
Author: Zheng, Li|Zhou, Zhongyong|He, Zhikuan
PMID: 26823712
Journal: Anticancer Agents Med Chem. 2016;16(4):432-9.
Title: miRNA-101 Suppresses Epithelial-to-Mesenchymal Transition by Targeting HMGA2 in Pancreatic Cancer Cells.
Author: Jiang, Wenli|Gu, Wen|Qiu, Ronglin|He, Songbing|Shen, Chenglong|Wu, Yaohao|Zhang, Jie|Zhou, Jiajia|Guo, Yixing|Wan, Daiwei|Li, Zhixi|Deng, Jiemin|Zeng, Lexiang|Tang, Jin|Zhou, Jin|Zhi, Qiaoming|Deng, Xiaogeng
PMID: 25968875
Journal: Med Princ Pract. 2016;25 Suppl 2:3-10.
Title: Novel Holistic Approaches for Overcoming Therapy Resistance in Pancreatic and Colon Cancers.
Author: Sarkar, Fazlul H
PMID: 26228733
Journal: Oncogene. 2016 Jun 23;35(25):3335-41.
Title: N-cadherin functions as a growth suppressor in a model of K-ras-induced PanIN.
Author: Su, Y|Li, J|Shi, C|Hruban, R H|Radice, G L
PMID: 26477318
Journal: Oncol Rep. 2016 Mar;35(3):1718-26.
Title: Resveratrol inhibits hypoxia-driven ROS-induced invasive and migratory ability of pancreatic cancer cells via suppression of the Hedgehog signaling pathway.
Author: Li, Wei|Cao, Lei|Chen, Xin|Lei, Jianjun|Ma, Qingyong
PMID: 26707376
Journal: Cold Spring Harb Protoc. 2016 Jan 4;2016(1):pdb.prot078352.
Title: Isolating Epithelial and Epithelial-to-Mesenchymal Transition Populations from Primary Tumors by Fluorescence-Activated Cell Sorting.
Author: Aiello, Nicole M|Rhim, Andrew D|Stanger, Ben Z
PMID: 26729901
Journal: Sci Rep. 2016 Jan 25;6:19819.
Title: Nimbolide inhibits pancreatic cancer growth and metastasis through ROS-mediated apoptosis and inhibition of epithelial-to-mesenchymal transition.
Author: Subramani, Ramadevi|Gonzalez, Elizabeth|Arumugam, Arunkumar|Nandy, Sushmita|Gonzalez, Viviana|Medel, Joshua|Camacho, Fernando|Ortega, Andrew|Bonkoungou, Sandrine|Narayan, Mahesh|Dwivedi, Alok kumar|Lakshmanaswamy, Rajkumar
PMID: 26804739
Journal: J Exp Clin Cancer Res. 2016 Feb 2;35:24.
Title: Epitelial-to-mesenchimal transition and invasion are upmodulated by tumor-expressed granzyme B and inhibited by docosahexaenoic acid in human colorectal cancer cells.
Author: D'Eliseo, Donatella|Di Rocco, Giuliana|Loria, Rossella|Soddu, Silvia|Santoni, Angela|Velotti, Francesca
PMID: 26830472
Journal: Methods Mol Biol. 2016;1395:163-87.
Title: The Role of MicroRNAs in Resistance to Current Pancreatic Cancer Treatment: Translational Studies and Basic Protocols for Extraction and PCR Analysis.
Author: Garajova, Ingrid|Le Large, Tessa Y S|Giovannetti, Elisa|Kazemier, Geert|Biasco, Guido|Peters, Godefridus J
PMID: 26910074
Journal: Radiother Oncol. 2016 May;119(2):282-90.
Title: Intraperitoneal (188)Re-Liposome delivery switches ovarian cancer metabolism from glycolysis to oxidative phosphorylation and effectively controls ovarian tumour growth in mice.
Author: Shen, Yao An|Lan, Keng Li|Chang, Chih Hsien|Lin, Liang Ting|He, Chun Lin|Chen, Po Hung|Lee, Te Wei|Lee, Yi Jang|Chuang, Chi Mu
PMID: 26915312
Journal: Cell. 2016 Feb 25;164(5):840-2.
Title: EMT: Matter of Life or Death?
Author: Gupta, Sonal|Maitra, Anirban
PMID: 26919422
Journal: Cell Death Differ. 2016 Aug;23(8):1358-70.
Title: TAp73 loss favors Smad-independent TGF-beta signaling that drives EMT in pancreatic ductal adenocarcinoma.
Author: Thakur, A K|Nigri, J|Lac, S|Leca, J|Bressy, C|Berthezene, P|Bartholin, L|Chan, P|Calvo, E|Iovanna, J L|Vasseur, S|Guillaumond, F|Tomasini, R
PMID: 26943320
Journal: Mol Pharm. 2016 Jun 6;13(6):1822-32.
Title: Micelle Mixtures for Coadministration of Gemcitabine and GDC-0449 To Treat Pancreatic Cancer.
Author: Karaca, Melek|Dutta, Rinku|Ozsoy, Yildiz|Mahato, Ram I
PMID: 26981724
Journal: Mol Pharm. 2016 Jul 5;13(7):2507-23.
Title: Glucocorticoid Receptor-Targeted Liposomal Codelivery of Lipophilic Drug and Anti-Hsp90 Gene: Strategy to Induce Drug-Sensitivity, EMT-Reversal, and Reduced Malignancy in Aggressive Tumors.
Author: Mondal, Sujan Kumar|Jinka, Sudhakar|Pal, Krishnendu|Nelli, Swetha|Dutta, Shamit Kumar|Wang, Enfeng|Ahmad, Ajaz|AlKharfy, Khalid M|Mukhopadhyay, Debabrata|Banerjee, Rajkumar
PMID: 27184196
Journal: Clin Cancer Res. 2016 Nov 15;22(22):5592-5604.
Title: CD44 Expression Level and Isoform Contributes to Pancreatic Cancer Cell Plasticity, Invasiveness, and Response to Therapy.
Author: Zhao, Shujie|Chen, Chen|Chang, Katherine|Karnad, Anand|Jagirdar, Jaishree|Kumar, Addanki P|Freeman, James W
PMID: 27267855
Journal: J Cell Physiol. 2016 Oct;231(10):2304.
Title: Retraction: "Activated K-Ras and INK4a/Arf Deficiency Promote Aggressiveness of Pancreatic Cancer by Induction of EMT Consistent With Cancer Stem Cell Phenotype" by Wang et al.
Author:
PMID: 27315162
Journal: Gastroenterology. 2016 Sep;151(3):540-553.e14.
Title: ETS-Transcription Factor ETV1 Regulates Stromal Expansion and Metastasis in Pancreatic Cancer.
Author: Heeg, Steffen|Das, Koushik K|Reichert, Maximilian|Bakir, Basil|Takano, Shigetsugu|Caspers, Julia|Aiello, Nicole M|Wu, Katherine|Neesse, Albrecht|Maitra, Anirban|Iacobuzio-Donahue, Christine A|Hicks, Philip|Rustgi, Anil K
PMID: 27318148
Journal: Am J Cancer Res. 2016 Jun 1;6(6):1384-95. eCollection 2016.
Title: Synergistic reversal effect of epithelial-to-mesenchymal transition by miR-223 inhibitor and genistein in gemcitabine-resistant pancreatic cancer cells.
Author: Ma, Jia|Zeng, Fanpeng|Ma, Cong|Pang, Haijie|Fang, Binbin|Lian, Chaoqun|Yin, Bin|Zhang, Xueping|Wang, Zhiwei|Xia, Jun
PMID: 27429851
Journal: Oxid Med Cell Longev. 2016;2016:5190314.
Title: Hyperglycemia Promotes the Epithelial-Mesenchymal Transition of Pancreatic Cancer via Hydrogen Peroxide.
Author: Li, Wei|Zhang, Lun|Chen, Xin|Jiang, Zhengdong|Zong, Liang|Ma, Qingyong
PMID: 27433288
Journal: Cancer Cell Int. 2016 Jul 22;16:57.
Title: Oridonin inhibits pancreatic cancer cell migration and epithelial-mesenchymal transition by suppressing Wnt/beta-catenin signaling pathway.
Author: Liu, Qian-Qian|Chen, Ke|Ye, Qiao|Jiang, Xiao-Hua|Sun, Yun-Wei
PMID: 27453691
Journal: Oncol Rep. 2016 Nov;36(5):2926-2934.
Title: Effect of PPM1H on malignant phenotype of human pancreatic cancer cells.
Author: Zhu, Han|Qin, Hua|Li, De-Min|Liu, Jing|Zhao, Qiu
PMID: 27599670
Journal: Sci Rep. 2016 Sep 14;6:32743.
Title: alpha-Mangostin-encapsulated PLGA nanoparticles inhibit pancreatic carcinogenesis by targeting cancer stem cells in human, and transgenic (Kras(G12D), and Kras(G12D)/tp53R270H) mice.
Author: Verma, Raj Kumar|Yu, Wei|Shrivastava, Anju|Shankar, Sharmila|Srivastava, Rakesh K
PMID: 27624879
Journal: Pancreatology. 2016 Nov - Dec;16(6):1005-1014.
Title: Nerve growth factor regulates CD133 function to promote tumor cell migration and invasion via activating ERK1/2 signaling in pancreatic cancer.
Author: Xin, Beibei|He, Xiaodan|Wang, Juan|Cai, Jun|Wei, Wei|Zhang, Ti|Shen, Xiaohong
PMID: 27654574
Journal: PLoS One. 2016 Oct 20;11(10):e0164811.
Title: Targeting Epithelial-Mesenchymal Transition for Identification of Inhibitors for Pancreatic Cancer Cell Invasion and Tumor Spheres Formation.
Author: Polireddy, Kishore|Dong, Ruochen|McDonald, Peter R|Wang, Tao|Luke, Brendan|Chen, Ping|Broward, Melinda|Roy, Anuradha|Chen, Qi
PMID: 27764163
Journal: Lab Invest. 2016 Dec;96(12):1268-1278.
Title: Inhibition of NF-kappa B pathway leads to deregulation of epithelial-mesenchymal transition and neural invasion in pancreatic cancer.
Author: Nomura, Alice|Majumder, Kaustav|Giri, Bhuwan|Dauer, Patricia|Dudeja, Vikas|Roy, Sabita|Banerjee, Sulagna|Saluja, Ashok K
PMID: 27775688
Journal: Am J Cancer Res. 2016 Oct 1;6(10):2192-2206. eCollection 2016.
Title: Radiation promotes epithelial-to-mesenchymal transition and invasion of pancreatic cancer cell by activating carcinoma-associated fibroblasts.
Author: Li, Doudou|Qu, Chao|Ning, Zhouyu|Wang, Haiyong|Zang, Kun|Zhuang, Liping|Chen, Lianyu|Wang, Peng|Meng, Zhiqiang
PMID: 27822411
Journal: Biomicrofluidics. 2016 Nov 29;10(6):064109.
Title: Automated electrorotation shows electrokinetic separation of pancreatic cancer cells is robust to acquired chemotherapy resistance, serum starvation, and EMT.
Author: Lannin, Timothy|Su, Wey-Wey|Gruber, Conor|Cardle, Ian|Huang, Chao|Thege, Fredrik|Kirby, Brian
PMID: 27990211
Journal: Oncoimmunology. 2016 Aug 12;5(12):e1221556.
Title: The pattern of hMENA isoforms is regulated by TGF-beta1 in pancreatic cancer and may predict patient outcome.
Author: Melchionna, Roberta|Iapicca, Pierluigi|Di Modugno, Francesca|Trono, Paola|Sperduti, Isabella|Fassan, Matteo|Cataldo, Ivana|Rusev, Borislav C|Lawlor, Rita T|Diodoro, Maria Grazia|Milella, Michele|Grazi, Gian Luca|Bissell, Mina J|Scarpa, Aldo|Nistico, Paola
PMID: 28123868
Journal: Oncotarget. 2017 Feb 14;8(7):10891-10904.
Title: Gedunin inhibits pancreatic cancer by altering sonic hedgehog signaling pathway.
Author: Subramani, Ramadevi|Gonzalez, Elizabeth|Nandy, Sushmita Bose|Arumugam, Arunkumar|Camacho, Fernando|Medel, Joshua|Alabi, Damilola|Lakshmanaswamy, Rajkumar
PMID: 26988754
Journal: Oncogene. 2017 Feb 2;36(5):687-699.
Title: Interleukin-17 promotes prostate cancer via MMP7-induced epithelial-to-mesenchymal transition.
Author: Zhang, Q|Liu, S|Parajuli, K R|Zhang, W|Zhang, K|Mo, Z|Liu, J|Chen, Z|Yang, S|Wang, A R|Myers, L|You, Z
PMID: 27375020
Journal: Mol Cancer Res. 2017 Jan;15(1):15-25.
Title: ECM Composition and Rheology Regulate Growth, Motility, and Response to Photodynamic Therapy in 3D Models of Pancreatic Ductal Adenocarcinoma.
Author: Cramer, Gwendolyn M|Jones, Dustin P|El-Hamidi, Hamid|Celli, Jonathan P
PMID: 27671335
Journal: Oncol Res. 2017 Apr 14;25(4):559-569.
Title: Upregulation of MicroRNA-935 Promotes the Malignant Behaviors of Pancreatic Carcinoma PANC-1 Cells via Targeting Inositol Polyphosphate 4-Phosphatase Type I Gene (INPP4A).
Author: Wang, Cuiyue|Feng, Zhen|Jiang, Kaitong|Zuo, Xiuli
PMID: 27733216
Journal: Int J Oncol. 2017 Jan;50(1):121-128.
Title: Prometastatic mechanisms of CAF-mediated EMT regulation in pancreatic cancer cells.
Author: Shan, Tao|Chen, Shuo|Chen, Xi|Lin, Wan Run|Li, Wei|Ma, Jiancang|Wu, Tao|Ji, Hong|Li, Yiming|Cui, Xijuan|Kang, Ya'an
PMID: 27878234
Journal: Int J Oncol. 2017 Jan;50(1):111-120.
Title: Oridonin inhibition and miR200b3p/ZEB1 axis in human pancreatic cancer.
Author: Gui, Zhifang|Luo, Feng|Yang, Yayang|Shen, Can|Li, Shuquan|Xu, Jian
PMID: 27878247
Journal: Oncogene. 2017 Apr 20;36(16):2202-2214.
Title: TGFbeta promotes mesenchymal phenotype of pancreatic cancer cells, in part, through epigenetic activation of VAV1.
Author: Huang, P-H|Lu, P-J|Ding, L-Y|Chu, P-C|Hsu, W-Y|Chen, C-S|Tsao, C-C|Chen, B-H|Lee, C-T|Shan, Y-S|Chen, C-S
PMID: 27893715
Journal: Oncol Res. 2017 Apr 14;25(4):605-615.
Title: CDGSH Iron Sulfur Domain 2 Activates Proliferation and EMT of Pancreatic Cancer Cells via Wnt/beta-Catenin Pathway and Has Prognostic Value in Human Pancreatic Cancer.
Author: Yang, Yang|Bai, Yuan-Song|Wang, Qing
PMID: 27983920
Journal: Transl Oncol. 2017 Feb;10(1):59-69.
Title: Acriflavine Inhibits Acquired Drug Resistance by Blocking the Epithelial-to-Mesenchymal Transition and the Unfolded Protein Response.
Author: Dekervel, Jeroen|Bulle, Ashenafi|Windmolders, Petra|Lambrechts, Diether|Van Cutsem, Eric|Verslype, Chris|van Pelt, Jos
PMID: 27987431
Journal: Am J Cancer Res. 2017 Jan 1;7(1):125-133. eCollection 2017.
Title: Curcumin suppresses epithelial-to-mesenchymal transition and metastasis of pancreatic cancer cells by inhibiting cancer-associated fibroblasts.
Author: Wang, Qing|Qu, Chao|Xie, Fang|Chen, Lianyu|Liu, Luming|Liang, Xiaohua|Wu, Xueyong|Wang, Peng|Meng, Zhiqiang
PMID: 28123853
Journal: Comb Chem High Throughput Screen. 2017;20(5):451-457.
Title: Development of In Vitro Co-Culture Model in Anti-Cancer Drug Development Cascade.
Author: Xu, Ruiling|Richards, Frances M
PMID: 28155598
Journal: J Cell Sci. 2017 Mar 15;130(6):1078-1093.
Title: The Aurora-A-Twist1 axis promotes highly aggressive phenotypes in pancreatic carcinoma.
Author: Wang, Jing|Nikhil, Kumar|Viccaro, Keith|Chang, Lei|Jacobsen, Max|Sandusky, George|Shah, Kavita
PMID: 28167680
Journal: BMC Biol. 2017 Feb 13;15(1):10.
Title: Phosphorylation-dependent regulation of ALDH1A1 by Aurora kinase A: insights on their synergistic relationship in pancreatic cancer.
Author: Wang, Jing|Nikhil, Kumar|Viccaro, Keith|Chang, Lei|White, Jacoba|Shah, Kavita
PMID: 28193222
Journal: Oncotarget. 2017 Apr 11;8(15):24978-24987.
Title: The mir-675-5p regulates the progression and development of pancreatic cancer via the UBQLN1-ZEB1-mir200 axis.
Author: Wang, Jue|Zhang, Youli|Wei, Hong|Zhang, Xingxing|Wu, Yan|Gong, Aihua|Xia, Yu|Wang, Wenbing|Xu, Min
PMID: 28212565
Journal: J Pathol. 2017 Jun;242(2):221-233.
Title: Thymidylate synthase is functionally associated with ZEB1 and contributes to the epithelial-to-mesenchymal transition of cancer cells.
Author: Siddiqui, Aarif|Vazakidou, Maria Eleni|Schwab, Annemarie|Napoli, Francesca|Fernandez-Molina, Cristina|Rapa, Ida|Stemmler, Marc P|Volante, Marco|Brabletz, Thomas|Ceppi, Paolo
PMID: 28337746
Journal: Technol Cancer Res Treat. 2017 Jan 1:1533034617700559.
Title: Long Noncoding RNA PVT1 Promotes EMT and Cell Proliferation and Migration Through Downregulating p21 in Pancreatic Cancer Cells.
Author: Wu, Bao-Qiang|Jiang, Yong|Zhu, Feng|Sun, Dong-Lin|He, Xiao-Zhou
PMID: 28355965
Journal: Nucleic Acids Res. 2017 Jun 20;45(11):6334-6349.
Title: Histone deacetylase class-I inhibition promotes epithelial gene expression in pancreatic cancer cells in a BRD4- and MYC-dependent manner.
Author: Mishra, Vivek Kumar|Wegwitz, Florian|Kosinsky, Robyn Laura|Sen, Madhobi|Baumgartner, Roland|Wulff, Tanja|Siveke, Jens T|Schildhaus, Hans-Ulrich|Najafova, Zeynab|Kari, Vijayalakshmi|Kohlhof, Hella|Hessmann, Elisabeth|Johnsen, Steven A
PMID: 28369619
Journal: Mol Cancer Res. 2017 Aug;15(8):1029-1039.
Title: miR-202 Diminishes TGFbeta Receptors and Attenuates TGFbeta1-Induced EMT in Pancreatic Cancer.
Author: Mody, Hardik R|Hung, Sau Wai|Pathak, Rakesh K|Griffin, Jazmine|Cruz-Monserrate, Zobeida|Govindarajan, Rajgopal
PMID: 28373289
Journal: Oncotarget. 2017 Jun 13;8(24):39048-39063.
Title: CBX7 negatively regulates migration and invasion in glioma via Wnt/beta-catenin pathway inactivation.
Author: Bao, Zhongyuan|Xu, Xiupeng|Liu, Yinlong|Chao, Honglu|Lin, Chao|Li, Zheng|You, Yongping|Liu, Ning|Ji, Jing
PMID: 28388562
Journal: BMC Cancer. 2017 Apr 7;17(1):249.
Title: Inhibition of Six1 affects tumour invasion and the expression of cancer stem cell markers in pancreatic cancer.
Author: Lerbs, Tristan|Bisht, Savita|Scholch, Sebastian|Pecqueux, Mathieu|Kristiansen, Glen|Schneider, Martin|Hofmann, Bianca T|Welsch, Thilo|Reissfelder, Christoph|Rahbari, Nuh N|Fritzmann, Johannes|Brossart, Peter|Weitz, Jurgen|Feldmann, Georg|Kahlert, Christop
PMID: 28388884
Journal: Nat Cell Biol. 2017 May;19(5):518-529.
Title: The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer.
Author: Krebs, Angela M|Mitschke, Julia|Lasierra Losada, Maria|Schmalhofer, Otto|Boerries, Melanie|Busch, Hauke|Boettcher, Martin|Mougiakakos, Dimitrios|Reichardt, Wilfried|Bronsert, Peter|Brunton, Valerie G|Pilarsky, Christian|Winkler, Thomas H|Brabletz, Simone|
PMID: 28414315
Journal: Nat Cell Biol. 2017 Apr 27;19(5):416-418.
Title: Context-specific roles of EMT programmes in cancer cell dissemination.
Author: Nieto, M Angela
PMID: 28446813
Journal: Cancer Lett. 2017 Aug 28;402:1-8.
Title: Chemosensitization and inhibition of pancreatic cancer stem cell proliferation by overexpression of microRNA-205.
Author: Chaudhary, Amit Kumar|Mondal, Goutam|Kumar, Virender|Kattel, Krishna|Mahato, Ram I
PMID: 28536008
Journal: Eur Rev Med Pharmacol Sci. 2017 May;21(10):2377-2384.
Title: Long non-coding RNA TUG1 can promote proliferation and migration of pancreatic cancer via EMT pathway.
Author: Qin, C-F|Zhao, F-L
PMID: 28617552
Journal: Nature. 2017 Jul 5;547(7661):E7-E8.
Title: Upholding a role for EMT in pancreatic cancer metastasis.
Author: Aiello, Nicole M|Brabletz, Thomas|Kang, Yibin|Nieto, M Angela|Weinberg, Robert A|Stanger, Ben Z
PMID: 28682339
Journal: Mol Pharm. 2017 Sep 5;14(9):3121-3133.
Title: EGFR-Targeted Cationic Polymeric Mixed Micelles for Codelivery of Gemcitabine and miR-205 for Treating Advanced Pancreatic Cancer.
Author: Mondal, Goutam|Almawash, Saud|Chaudhary, Amit Kumar|Mahato, Ram I
PMID: 28719220
Journal: Naunyn Schmiedebergs Arch Pharmacol. 2017 Nov;390(11):1125-1134.
Title: A marginal anticancer effect of regorafenib on pancreatic carcinoma cells in vitro, ex vivo, and in vivo.
Author: Mayer, Barbara|Karakhanova, Svetlana|Bauer, Nathalie|Liu, Li|Zhu, Yifan|Philippov, Pavel P|Werner, Jens|Bazhin, Alexandr V
PMID: 28779210
Journal: Sci Rep. 2017 Aug 30;7(1):10060.
Title: ITGA1 is a pre-malignant biomarker that promotes therapy resistance and metastatic potential in pancreatic cancer.
Author: Gharibi, Armen|La Kim, Sa|Molnar, Justin|Brambilla, Daniel|Adamian, Yvess|Hoover, Malachia|Hong, Julie|Lin, Joy|Wolfenden, Laurelin|Kelber, Jonathan A
PMID: 28855593
Journal: Cancers (Basel). 2017 Sep 12;9(9). pii: cancers9090122.
Title: EMT and Treatment Resistance in Pancreatic Cancer.
Author: Gaianigo, Nicola|Melisi, Davide|Carbone, Carmine
PMID: 28895920
Journal: Sci Rep. 2017 Sep 13;7(1):11501.
Title: Semaphorin 3 C drives epithelial-to-mesenchymal transition, invasiveness, and stem-like characteristics in prostate cells.
Author: Tam, Kevin J|Hui, Daniel H F|Lee, Wilson W|Dong, Mingshu|Tombe, Tabitha|Jiao, Ivy Z F|Khosravi, Shahram|Takeuchi, Ario|Peacock, James W|Ivanova, Larissa|Moskalev, Igor|Gleave, Martin E|Buttyan, Ralph|Cox, Michael E|Ong, Christopher J
PMID: 28904399
Journal: Oncol Lett. 2017 Oct;14(4):4883-4889.
Title: Kruppel-like factor 8 induces epithelial-to-mesenchymal transition and promotes invasion of pancreatic cancer cells through transcriptional activation of four and a half LIM-only protein 2.
Author: Yi, Xiaoping|Zai, Hongyan|Long, Xueying|Wang, Xiaoyi|Li, Wenzheng|Li, Yixiong
PMID: 28943967
Journal: Oncotarget. 2017 Jun 27;8(37):61674-61686.
Title: Silencing IGFBP-2 decreases pancreatic cancer metastasis and enhances chemotherapeutic sensitivity.
Author: Liu, Huan|Li, Le|Chen, Hua|Kong, Rui|Pan, Shangha|Hu, Jisheng|Wang, Yongwei|Li, Yilong|Sun, Bei
PMID: 28977895
Journal: Cell Death Dis. 2017 Oct 19;8(10):e3129.
Title: miR-3656 expression enhances the chemosensitivity of pancreatic cancer to gemcitabine through modulation of the RHOF/EMT axis.
Author: Yang, Rui-Meng|Zhan, Ming|Xu, Sun-Wang|Long, Man-Mei|Yang, Lin-Hua|Chen, Wei|Huang, Shuai|Liu, Qiang|Zhou, Jun|Zhu, Jun|Wang, Jian
PMID: 29048402
Journal: Oncotarget. 2017 Aug 10;8(43):74406-74422.
Title: Tenascin-C induces migration and invasion through JNK/c-Jun signalling in pancreatic cancer.
Author: Cai, Jun|Du, Shaoxia|Wang, Hui|Xin, Beibei|Wang, Juan|Shen, Wenyuan|Wei, Wei|Guo, Zhongkui|Shen, Xiaohong
PMID: 29088796
Journal: Cell Death Dis. 2017 Nov 9;8(11):e3168.
Title: Alternative polyadenylation of ZEB1 promotes its translation during genotoxic stress in pancreatic cancer cells.
Author: Passacantilli, Ilaria|Panzeri, Valentina|Bielli, Pamela|Farini, Donatella|Pilozzi, Emanuela|Fave, Gianfranco Delle|Capurso, Gabriele|Sette, Claudio
PMID: 29120411
Journal: Mol Cancer. 2017 Nov 9;16(1):169.
Title: Long noncoding RNA NORAD, a novel competing endogenous RNA, enhances the hypoxia-induced epithelial-mesenchymal transition to promote metastasis in pancreatic cancer.
Author: Li, Hongzhe|Wang, Xinjing|Wen, Chenlei|Huo, Zhen|Wang, Weishen|Zhan, Qian|Cheng, Dongfeng|Chen, Hao|Deng, Xiaxing|Peng, Chenghong|Shen, Baiyong
PMID: 29121972
Journal: Zhonghua Wai Ke Za Zhi. 2017 Nov 1;55(11):857-862.
Title: [Bit1 mediates the malignant behaviors in pancreatic cancer and its potential clinical significance].
Author: Huang, S|Yuan, D|Guo, J C|Zhang, T P|Zhao, Y P
PMID: 29136735
Journal: Biomed Pharmacother. 2017 Dec;96:1341-1348.
Title: miR-135b-5p Promotes migration, invasion and EMT of pancreatic cancer cells by targeting NR3C2.
Author: Zhang, Zhengliang|Che, Xiangming|Yang, Ni|Bai, Zhenghai|Wu, Yuan|Zhao, Li|Pei, Honghong
PMID: 29196101
Journal: J Exp Clin Cancer Res. 2017 Dec 19;36(1):187.
Title: 5-FU resistant EMT-like pancreatic cancer cells are hypersensitive to photochemical internalization of the novel endoglin-targeting immunotoxin CD105-saporin.
Author: Lund, Kaja|Olsen, Cathrine Elisabeth|Wong, Judith Jing Wen|Olsen, Petter Angell|Solberg, Nina Therese|Hogset, Anders|Krauss, Stefan|Selbo, Pal Kristian
PMID: 29258566
Journal: Oncotarget. 2017 Nov 30;8(67):111333-111345.
Title: Aberrant expression of STYK1 and E-cadherin confer a poor prognosis for pancreatic cancer patients.
Author: Chen, Luguang|Ma, Chao|Bian, Yun|Shao, Chengwei|Wang, Tiegong|Li, Jing|Chong, Xiaodan|Su, Li|Lu, Jianping
PMID: 29340057
Journal: Small GTPases. 2018 Nov 2;9(6):452-456.
Title: Targeting integrin-linked kinase to suppress oncogenic KRAS signaling in pancreatic cancer.
Author: Chu, Po-Chen|Kulp, Samuel K|Bekaii-Saab, Tanios|Chen, Ching-Shih
PMID: 27936345
Journal: J Cell Biochem. 2018 Feb;119(2):1855-1865.
Title: The inhibitory effect of 5,7-DMF on pancreatic sphere-forming cell function mediated by FoxM1 gene expression.
Author: Zeng, Deyu|Ma, Jian|Li, Rongrong|Yang, Jianfeng|Yin, Xianli
PMID: 28802012
Journal: Biochim Biophys Acta Mol Basis Dis. 2018 Jan;1864(1):197-207.
Title: TOP2A induces malignant character of pancreatic cancer through activating beta-catenin signaling pathway.
Author: Pei, Yao-Fei|Yin, Xi-Min|Liu, Xi-Qiang
PMID: 29045811
Journal: Int J Obes (Lond). 2018 Mar;42(3):334-343.
Title: Adipocytes sustain pancreatic cancer progression through a non-canonical WNT paracrine network inducing ROR2 nuclear shuttling.
Author: Carbone, C|Piro, G|Gaianigo, N|Ligorio, F|Santoro, R|Merz, V|Simionato, F|Zecchetto, C|Falco, G|Conti, G|Kamga, P T|Krampera, M|Di Nicolantonio, F|De Franceschi, L|Scarpa, A|Tortora, G|Melisi, D
PMID: 29151594
Journal: Yonsei Med J. 2018 Jan;59(1):20-27.
Title: Pseudolaric Acid B Inhibits Proliferation, Invasion and Epithelial-to-Mesenchymal Transition in Human Pancreatic Cancer Cell.
Author: Li, Xiaoyu|Zhao, Xianzhi|Song, Wen|Tian, Zibin|Yang, Lin|Niu, Qinghui|Zhang, Qi|Xie, Man|Zhou, Bin|Xu, Yonghong|Wu, Jun|Zhang, Cuiping
PMID: 29214772
Journal: J Exp Clin Cancer Res. 2018 Jan 12;37(1):4.
Title: Microfluidic co-culture of pancreatic tumor spheroids with stellate cells as a novel 3D model for investigation of stroma-mediated cell motility and drug resistance.
Author: Lee, Ji-Hyun|Kim, Seul-Ki|Khawar, Iftikhar Ali|Jeong, Su-Yeong|Chung, Seok|Kuh, Hyo-Jeong
PMID: 29329547
Journal: Oncol Res. 2018 Aug 23;26(7):1123-1131.
Title: Phosphoglycerate Mutase 1 (PGAM1) Promotes Pancreatic Ductal Adenocarcinoma (PDAC) Metastasis by Acting as a Novel Downstream Target of the PI3K/Akt/mTOR Pathway.
Author: Liu, Xinlu|Tan, Xiaodong|Liu, Peng|Wu, Yunhao|Qian, Songying|Zhang, Xiaobo
PMID: 29386088
Journal: Oncotarget. 2017 Dec 7;9(1):306-320.
Title: Prognostic significance of E-cadherin and ZEB1 expression in intraductal papillary mucinous neoplasm.
Author: Chang, Ye Rim|Park, Taesung|Park, Sung Hyo|Kim, Yong Kang|Lee, Kyoung Bun|Kim, Sun-Whe|Jang, Jin-Young
PMID: 29416615
Journal: J Cancer. 2018 Jan 5;9(3):614-628.
Title: The role of cancer-associated fibroblast MRC-5 in pancreatic cancer.
Author: Ding, Song-Ming|Lu, Ai-Li|Zhang, Wu|Zhou, Lin|Xie, Hai-Yang|Zheng, Shu-Sen|Li, Qi-Yong
PMID: 29483967
Journal: Cell Physiol Biochem. 2018;46(1):238-252.
Title: Kruppel-Like Factor 4 Inhibits Pancreatic Cancer Epithelial-to-Mesenchymal Transition and Metastasis by Down-Regulating Caveolin-1 Expression.
Author: Zhu, Zhonglin|Yu, Zhilong|Wang, Jianfeng|Zhou, Lisheng|Zhang, Jing|Yao, Bin|Dou, Jin|Qiu, Zhengjun|Huang, Chen
PMID: 29587259
Journal: Anticancer Res. 2018 Apr;38(4):1937-1946.
Title: MEKK3 Sustains EMT and Stemness in Pancreatic Cancer by Regulating YAP and TAZ Transcriptional Activity.
Author: Santoro, Raffaela|Zanotto, Marco|Carbone, Carmine|Piro, Geny|Tortora, Giampaolo|Melisi, Davide
PMID: 29599309
Journal: Oncotarget. 2018 Apr 6;9(26):18239-18253.
Title: Leptin-Notch axis impairs 5-fluorouracil effects on pancreatic cancer.
Author: Harbuzariu, Adriana|Gonzalez-Perez, Ruben Rene
PMID: 29719602
Journal: Oncol Lett. 2018 May;15(5):7144-7152.
Title: Conversion of epithelial-to-mesenchymal transition to mesenchymal-to-epithelial transition is mediated by oxygen concentration in pancreatic cancer cells.
Author: Chen, Shuo|Chen, Xi|Li, Wei|Shan, Tao|Lin, Wan Run|Ma, Jiancang|Cui, Xijuan|Yang, Wenbin|Cao, Gang|Li, Yiming|Wang, Li|Kang, Ya'an
PMID: 29731878
Journal: PLoS One. 2018 Jun 1;13(6):e0198038.
Title: A receptor tyrosine kinase ROR1 inhibitor (KAN0439834) induced significant apoptosis of pancreatic cells which was enhanced by erlotinib and ibrutinib.
Author: Daneshmanesh, Amir Hossein|Hojjat-Farsangi, Mohammad|Ghaderi, Amineh|Moshfegh, Ali|Hansson, Lotta|Schultz, Johan|Vagberg, Jan|Bystrom, Styrbjorn|Olsson, Elisabeth|Olin, Thomas|Osterborg, Anders|Mellstedt, Hakan
PMID: 29856777
Journal: Cancer Lett. 2018 Sep 1;431:96-104.
Title: Overexpression of MIST1 reverses the epithelial-mesenchymal transition and reduces the tumorigenicity of pancreatic cancer cells via the Snail/E-cadherin pathway.
Author: Li, Xiaogang|Chen, Hengyu|Liu, Zhiqiang|Ye, Zeng|Gou, Shanmiao|Wang, Chunyou
PMID: 29859299
Journal: Cell Death Dis. 2018 Jun 13;9(6):706.
Title: Linc00462 promotes pancreatic cancer invasiveness through the miR-665/TGFBR1-TGFBR2/SMAD2/3 pathway.
Author: Zhou, Bin|Guo, Weidong|Sun, Chuandong|Zhang, Bingyuan|Zheng, Fang
PMID: 29899418
Journal: Dev Cell. 2018 Jun 18;45(6):663-665.
Title: EMT in Metastasis: Finding the Right Balance.
Author: Lo, Hin Ching|Zhang, Xiang H-F
PMID: 29920271
Journal: Sci Rep. 2018 Jun 29;8(1):9846.
Title: Clinical Implications of Lysyl Oxidase-Like Protein 2 Expression in Pancreatic Cancer.
Author: Tanaka, Nobutake|Yamada, Suguru|Sonohara, Fuminori|Suenaga, Masaya|Hayashi, Masamichi|Takami, Hideki|Niwa, Yukiko|Hattori, Norifumi|Iwata, Naoki|Kanda, Mitsuro|Tanaka, Chie|Kobayashi, Daisuke|Nakayama, Goro|Koike, Masahiko|Fujiwara, Michitaka|Fujii, Tsuto
PMID: 29959362
Journal: Oncol Lett. 2018 Jul;16(1):924-930.
Title: Knockdown of FUT3 disrupts the proliferation, migration, tumorigenesis and TGF-beta induced EMT in pancreatic cancer cells.
Author: Zhan, Ling|Chen, Lianyu|Chen, Zhen
PMID: 29963165
Journal: Int J Cancer. 2018 Jul 6.
Title: Long non-coding RNA lnc-PCTST predicts prognosis through inhibiting progression of pancreatic cancer by downregulation of TACC-3.
Author: Wang, Yandong|Ding, Xiangya|Hu, Hao|Yuan, He|Lu, Zipeng|Wu, Pengfei|Tian, Lei|Xia, Tianfang|Yin, Jie|Yuan, Hao|Shi, Guodong|Liu, Dongfang|Jiang, Kuirong|Miao, Yi
PMID: 29978472
Journal: Cell Death Dis. 2018 Jul 23;9(8):802.
Title: Overexpression of PEAK1 contributes to epithelial-mesenchymal transition and tumor metastasis in lung cancer through modulating ERK1/2 and JAK2 signaling.
Author: Ding, Chenbo|Tang, Wendong|Fan, Xiaobo|Wang, Xiyong|Wu, Hairu|Xu, Hongbo|Xu, Wei|Gao, Wei|Wu, Guoqiu
PMID: 30038287
Journal: Cell Death Dis. 2018 Jul 24;9(8):807.
Title: MiR-361-3p regulates ERK1/2-induced EMT via DUSP2 mRNA degradation in pancreatic ductal adenocarcinoma.
Author: Hu, Jisheng|Li, Le|Chen, Hongze|Zhang, Guangquan|Liu, Huan|Kong, Rui|Chen, Hua|Wang, Yongwei|Li, Yilong|Tian, Fengyu|Lv, Xinjian|Li, Guanqun|Sun, Bei
PMID: 30042387
Journal: Cancers (Basel). 2018 Jul 31;10(8). pii: cancers10080254.
Title: TGF-betaRII Knock-down in Pancreatic Cancer Cells Promotes Tumor Growth and Gemcitabine Resistance. Importance of STAT3 Phosphorylation on S727.
Author: Drubay, Vincent|Skrypek, Nicolas|Cordiez, Lucie|Vasseur, Romain|Schulz, Celine|Boukrout, Nihad|Duchene, Belinda|Coppin, Lucie|Van Seuningen, Isabelle|Jonckheere, Nicolas
PMID: 30065235
Journal: Theranostics. 2018 Jun 13;8(14):3824-3840.
Title: Targeting S1PR1/STAT3 loop abrogates desmoplasia and chemosensitizes pancreatic cancer to gemcitabine.
Author: Lankadasari, Manendra Babu|Aparna, Jayasekharan S|Mohammed, Sabira|James, Shirley|Aoki, Kazunori|Binu, Valsalakumari S|Nair, Sindhu|Harikumar, Kuzhuvelil B
PMID: 30083262
Journal: Sci Rep. 2018 Aug 15;8(1):12176.
Title: Long non-coding RNA HOTAIR promotes tumorigenesis and forecasts a poor prognosis in cholangiocarcinoma.
Author: Qin, Wei|Kang, Pengcheng|Xu, Yi|Leng, Kaiming|Li, Zhenglong|Huang, Lining|Gao, Jianjun|Cui, Yunfu|Zhong, Xiangyu
PMID: 30111807
Journal: EMBO Mol Med. 2018 Aug 17. pii: emmm.201809085.
Title: Dual reporter genetic mouse models of pancreatic cancer identify an epithelial-to-mesenchymal transition-independent metastasis program.
Author: Chen, Yang|LeBleu, Valerie S|Carstens, Julienne L|Sugimoto, Hikaru|Zheng, Xiaofeng|Malasi, Shruti|Saur, Dieter|Kalluri, Raghu
PMID: 30120146
Journal: Front Immunol. 2018 Aug 15;9:1844.
Title: Human Surfactant Protein D Suppresses Epithelial-to-Mesenchymal Transition in Pancreatic Cancer Cells by Downregulating TGF-beta.
Author: Kaur, Anuvinder|Riaz, Muhammad Suleman|Singh, Shiv K|Kishore, Uday
PMID: 30158928
Journal: Pancreatology. 2018 Aug 23. pii: S1424-3903(18)30656-2.
Title: Overexpression of GP73 promotes cell invasion, migration and metastasis by inducing epithelial-mesenchymal transition in pancreatic cancer.
Author: Song, Yin-Xue|Xu, Zhi-Chao|Li, Hui-Ling|Yang, Pei-Lei|Du, Jun-Kai|Xu, Jing
PMID: 30217697
Journal: Cancer Res. 2018 Oct 19. pii: 0008-5472.CAN-18-0753.
Title: TGFbeta-activated USP27X deubiquitinase regulates cell migration and chemoresistance via stabilization of Snail1.
Author: Lambies, Guillem|Miceli, Martina|Martinez-Guillamon, Catalina|Olivera-Salguero, Ruben|Pena, Raul|Frias, Carolina-Paola|Calderon, Irene|Atanassov, Boyko S|Dent, Sharon Y R|Arribas, Joaquin|Garcia de Herreros, Antonio|Diaz, Victor M
PMID: 30341066