Primary Site >> Pancreatic Cancer
Gene >> ITK
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Ref: N-cadherin expression and epithelial-mesenchymal transition in pancreatic carcinoma. PMID: 15217949 |
Ref: Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer. PMID: 17114584 Ref: Implication of EMT induced by TGF-beta1 in pancreatic cancer. PMID: 17357493 |
Ref: Tyrosine kinase receptor RON in human pancreatic cancer: expression, function, and validation as a target. PMID: 17311308 Ref: Development and characterization of gemcitabine-resistant pancreatic tumor cells. PMID: 17909916 |
Ref: Loss of type III transforming growth factor beta receptor expression increases motility and invasiveness associated with epithelial to mesenchymal transition during pancreatic cancer progression. PMID: 17999987 Ref: Collagen I-mediated up-regulation of N-cadherin requires cooperative signals from integrins and discoidin domain receptor 1. PMID: 18362184 Ref: [Two cases of anaplastic carcinoma of the pancreas in terms of the diversity of carcinoma cells (epithelial-mesenchymal transition; EMT)]. PMID: 18987452 |
Ref: Integrative genomic analyses of ZEB2: Transcriptional regulation of ZEB2 based on SMADs, ETS1, HIF1alpha, POU/OCT, and NF-kappaB. PMID: 19424592 Ref: Integrative genomic analyses on GLI1: positive regulation of GLI1 by Hedgehog-GLI, TGFbeta-Smads, and RTK-PI3K-AKT signals, and negative regulation of GLI1 by Notch-CSL-HES/HEY, and GPCR-Gs-PKA signals. PMID: 19513567 Ref: Up-regulation of miR-200 and let-7 by natural agents leads to the reversal of epithelial-to-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells. PMID: 19654291 Ref: A resource for analysis of microRNA expression and function in pancreatic ductal adenocarcinoma cells. PMID: 20037478 Ref: Tumor initiating cells in pancreatic cancer: A critical view. PMID: 21607102 |
Ref: Loss of FOXA1/2 is essential for the epithelial-to-mesenchymal transition in pancreatic cancer. PMID: 20160041 Ref: SNAIL induces epithelial-to-mesenchymal transition in a human pancreatic cancer cell line (BxPC3) and promotes distant metastasis and invasiveness in vivo. PMID: 20576520 Ref: AZGP1 is a tumor suppressor in pancreatic cancer inducing mesenchymal-to-epithelial transdifferentiation by inhibiting TGF-beta-mediated ERK signaling. PMID: 20581862 |
Ref: Cyr61/CCN1 signaling is critical for epithelial-mesenchymal transition and stemness and promotes pancreatic carcinogenesis. PMID: 21232118 Ref: Silencing of hHS6ST2 inhibits progression of pancreatic cancer through inhibition of Notch signalling. PMID: 21443520 Ref: Over-expression of FoxM1 leads to epithelial-mesenchymal transition and cancer stem cell phenotype in pancreatic cancer cells. PMID: 21503965 Ref: Anti-VEGF treatment-resistant pancreatic cancers secrete proinflammatory factors that contribute to malignant progression by inducing an EMT cell phenotype. PMID: 21737511 |
Ref: GLI1 inhibition promotes epithelial-to-mesenchymal transition in pancreatic cancer cells. PMID: 22086851 Ref: Contribution of epithelial-to-mesenchymal transition and cancer stem cells to pancreatic cancer progression. PMID: 22099597 Ref: EMT and dissemination precede pancreatic tumor formation. PMID: 22265420 Ref: Molecular profiling of pancreatic neuroendocrine tumors in sporadic and Von Hippel-Lindau patients. PMID: 22461457 Ref: Inhibition of mesothelin as a novel strategy for targeting cancer cells. PMID: 22485139 Ref: CCN5/WISP-2: A micromanager of breast cancer progression. PMID: 22487979 Ref: JDP2 inhibits the epithelial-to-mesenchymal transition in pancreatic cancer BxPC3 cells. PMID: 22535371 Ref: Role of Cripto-1 during epithelial-to-mesenchymal transition in development and cancer. PMID: 22542493 Ref: BMP2 induces PANC-1 cell invasion by MMP-2 overexpression through ROS and ERK. PMID: 22652796 Ref: Pancreatic cancer cells retain the epithelial-related phenotype and modify mitotic spindle microtubules after the administration of ukrain in vitro. PMID: 22700003 Ref: Emerging frontiers in pancreatic cancer research: elaboration of key genes, cells and the extracellular milieu. PMID: 22759592 Ref: GLI1 modulates EMT in pancreatic cancer--letter. PMID: 22761339 Ref: Neoadjuvant chemotherapy with gemcitabine for pancreatic cancer increases in situ expression of the apoptosis marker M30 and stem cell marker CD44. PMID: 22783415 Ref: Apricoxib, a novel inhibitor of COX-2, markedly improves standard therapy response in molecularly defined models of pancreatic cancer. PMID: 22829202 Ref: Molecular markers associated with outcome and metastasis in human pancreatic cancer. PMID: 22925330 Ref: Chemoresistance is associated with cancer stem cell-like properties and epithelial-to-mesenchymal transition in pancreatic cancer cells. PMID: 22993328 Ref: The matricellular protein CCN1/Cyr61 is a critical regulator of Sonic Hedgehog in pancreatic carcinogenesis. PMID: 23027863 Ref: The Role of EMT in Pancreatic Cancer Progression. PMID: 23145368 Ref: Epithelial-to-mesenchymal transition in pancreatic ductal adenocarcinoma and pancreatic tumor cell lines: the role of neutrophils and neutrophil-derived elastase. PMID: 23227088 Ref: Hypoxia-induced aggressiveness of pancreatic cancer cells is due to increased expression of VEGF, IL-6 and miR-21, which can be attenuated by CDF treatment. PMID: 23272057 Ref: Cancer Stem Cells, EMT, and Developmental Pathway Activation in Pancreatic Tumors. PMID: 24213498 |
Ref: Macrophage migration inhibitory factor induces epithelial to mesenchymal transition, enhances tumor aggressiveness and predicts clinical outcome in resected pancreatic ductal adenocarcinoma. PMID: 22821831 Ref: Deguelin suppresses pancreatic tumor growth and metastasis by inhibiting epithelial-to-mesenchymal transition in an orthotopic model. PMID: 22986522 Ref: Sulforaphane regulates self-renewal of pancreatic cancer stem cells through the modulation of Sonic hedgehog-GLI pathway. PMID: 23129257 Ref: Delta like ligand 4 induces impaired chemo-drug delivery and enhanced chemoresistance in pancreatic cancer. PMID: 23200678 Ref: Lipocalin-2 is associated with a good prognosis and reversing epithelial-to-mesenchymal transition in pancreatic cancer. PMID: 23539193 Ref: Epithelial to mesenchymal transition and the generation of stem-like cells in pancreatic cancer. PMID: 23561968 Ref: BIBF 1120 (nintedanib), a triple angiokinase inhibitor, induces hypoxia but not EMT and blocks progression of preclinical models of lung and pancreatic cancer. PMID: 23729403 Ref: Snail cooperates with KrasG12D to promote pancreatic fibrosis. PMID: 23761168 Ref: WNT5A/JNK signaling regulates pancreatic cancer cells migration by Phosphorylating Paxillin. PMID: 23890137 Ref: SOX2 promotes dedifferentiation and imparts stem cell-like features to pancreatic cancer cells. PMID: 23917223 Ref: Targeting cancer-related inflammation: Chinese herbal medicine inhibits epithelial-to-mesenchymal transition in pancreatic cancer. PMID: 23922983 Ref: Resveratrol inhibits the epithelial-mesenchymal transition of pancreatic cancer cells via suppression of the PI-3K/Akt/NF-kappaB pathway. PMID: 23992306 Ref: Epithelial-to-mesenchymal transition predicts prognosis of pancreatic cancer. PMID: 24075276 Ref: Upregulation of Wnt5a promotes epithelial-to-mesenchymal transition and metastasis of pancreatic cancer cells. PMID: 24156409 Ref: Overexpression of COL11A1 by cancer-associated fibroblasts: clinical relevance of a stromal marker in pancreatic cancer. PMID: 24194920 Ref: MicroRNA-200c modulates the expression of MUC4 and MUC16 by directly targeting their coding sequences in human pancreatic cancer. PMID: 24204560 |
Ref: Par-4 downregulation confers cisplatin resistance in pancreatic cancer cells via PI3K/Akt pathway-dependent EMT. PMID: 24144893 Ref: Pancreatic cancer-associated retinoblastoma 1 dysfunction enables TGF-beta to promote proliferation. PMID: 24334458 Ref: FOXM1c promotes pancreatic cancer epithelial-to-mesenchymal transition and metastasis via upregulation of expression of the urokinase plasminogen activator system. PMID: 24452790 Ref: Snail contributes to the maintenance of stem cell-like phenotype cells in human pancreatic cancer. PMID: 24489910 Ref: MiR-200a inhibits epithelial-mesenchymal transition of pancreatic cancer stem cell. PMID: 24521357 Ref: Effects of the HIF-1alpha and NF-kappaB loop on epithelial-mesenchymal transition and chemoresistance induced by hypoxia in pancreatic cancer cells. PMID: 24535079 Ref: The low chamber pancreatic cancer cells had stem-like characteristics in modified transwell system: is it a novel method to identify and enrich cancer stem-like cells? PMID: 24689055 Ref: Embelin suppresses growth of human pancreatic cancer xenografts, and pancreatic cancer cells isolated from KrasG12D mice by inhibiting Akt and Sonic hedgehog pathways. PMID: 24694877 Ref: Targeting insulin-like growth factor 1 receptor inhibits pancreatic cancer growth and metastasis. PMID: 24809702 Ref: How to explain the contradiction of microRNA 200c expression and survival in solid tumors? A meta-analysis. PMID: 24870778 Ref: XMD8-92 inhibits pancreatic tumor xenograft growth via a DCLK1-dependent mechanism. PMID: 24880079 Ref: Upregulation of autophagy by hypoxia-inducible factor-1alpha promotes EMT and metastatic ability of CD133+ pancreatic cancer stem-like cells during intermittent hypoxia. PMID: 24994549 Ref: Surprisal analysis characterizes the free energy time course of cancer cells undergoing epithelial-to-mesenchymal transition. PMID: 25157127 Ref: AXL kinase as a novel target for cancer therapy. PMID: 25337673 |
Ref: Mutated K-ras activates CDK8 to stimulate the epithelial-to-mesenchymal transition in pancreatic cancer in part via the Wnt/beta-catenin signaling pathway. PMID: 25305448 Ref: MiR-23a/-24-induced gene silencing results in mesothelial cell integration of pancreatic cancer. PMID: 25422915 Ref: Vitamin D receptor signaling and pancreatic cancer cell EMT. PMID: 25506892 Ref: Alisertib induces cell cycle arrest and autophagy and suppresses epithelial-to-mesenchymal transition involving PI3K/Akt/mTOR and sirtuin 1-mediated signaling pathways in human pancreatic cancer cells. PMID: 25632225 Ref: Down-regulation of miR-223 reverses epithelial-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells. PMID: 25638153 Ref: Slug-dependent upregulation of L1CAM is responsible for the increased invasion potential of pancreatic cancer cells following long-term 5-FU treatment. PMID: 25860483 Ref: Epithelial-mesenchymal, mesenchymal-epithelial, and endothelial-mesenchymal transitions in malignant tumors: An update. PMID: 25984514 Ref: ROBO3 promotes growth and metastasis of pancreatic carcinoma. PMID: 26070964 Ref: Zidovudine, an anti-viral drug, resensitizes gemcitabine-resistant pancreatic cancer cells to gemcitabine by inhibition of the Akt-GSK3beta-Snail pathway. PMID: 26111057 Ref: miR-33a suppresses the nuclear translocation of beta-catenin to enhance gemcitabine sensitivity in human pancreatic cancer cells. PMID: 26113407 Ref: Characterization of Mouse Models of Early Pancreatic Lesions Induced by Alcohol and Chronic Pancreatitis. PMID: 26166469 Ref: Loss of ATM accelerates pancreatic cancer formation and epithelial-mesenchymal transition. PMID: 26220524 Ref: Polyphenols from marine brown algae target radiotherapy-coordinated EMT and stemness-maintenance in residual pancreatic cancer. PMID: 26395574 Ref: PI3K/AKT/mTOR and sonic hedgehog pathways cooperate together to inhibit human pancreatic cancer stem cell characteristics and tumor growth. PMID: 26451606 Ref: Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer. PMID: 26560028 Ref: Metformin Reduces Desmoplasia in Pancreatic Cancer by Reprogramming Stellate Cells and Tumor-Associated Macrophages. PMID: 26641266 Ref: Knockdown of PFTK1 inhibits tumor cell proliferation, invasion and epithelial-to-mesenchymal transition in pancreatic cancer. PMID: 26823712 |
Ref: miRNA-101 Suppresses Epithelial-to-Mesenchymal Transition by Targeting HMGA2 in Pancreatic Cancer Cells. PMID: 25968875 Ref: Novel Holistic Approaches for Overcoming Therapy Resistance in Pancreatic and Colon Cancers. PMID: 26228733 Ref: N-cadherin functions as a growth suppressor in a model of K-ras-induced PanIN. PMID: 26477318 Ref: Resveratrol inhibits hypoxia-driven ROS-induced invasive and migratory ability of pancreatic cancer cells via suppression of the Hedgehog signaling pathway. PMID: 26707376 Ref: Isolating Epithelial and Epithelial-to-Mesenchymal Transition Populations from Primary Tumors by Fluorescence-Activated Cell Sorting. PMID: 26729901 Ref: Nimbolide inhibits pancreatic cancer growth and metastasis through ROS-mediated apoptosis and inhibition of epithelial-to-mesenchymal transition. PMID: 26804739 Ref: Epitelial-to-mesenchimal transition and invasion are upmodulated by tumor-expressed granzyme B and inhibited by docosahexaenoic acid in human colorectal cancer cells. PMID: 26830472 Ref: The Role of MicroRNAs in Resistance to Current Pancreatic Cancer Treatment: Translational Studies and Basic Protocols for Extraction and PCR Analysis. PMID: 26910074 Ref: Intraperitoneal (188)Re-Liposome delivery switches ovarian cancer metabolism from glycolysis to oxidative phosphorylation and effectively controls ovarian tumour growth in mice. PMID: 26915312 Ref: EMT: Matter of Life or Death? PMID: 26919422 Ref: TAp73 loss favors Smad-independent TGF-beta signaling that drives EMT in pancreatic ductal adenocarcinoma. PMID: 26943320 Ref: Micelle Mixtures for Coadministration of Gemcitabine and GDC-0449 To Treat Pancreatic Cancer. PMID: 26981724 Ref: Glucocorticoid Receptor-Targeted Liposomal Codelivery of Lipophilic Drug and Anti-Hsp90 Gene: Strategy to Induce Drug-Sensitivity, EMT-Reversal, and Reduced Malignancy in Aggressive Tumors. PMID: 27184196 Ref: CD44 Expression Level and Isoform Contributes to Pancreatic Cancer Cell Plasticity, Invasiveness, and Response to Therapy. PMID: 27267855 Ref: Retraction: "Activated K-Ras and INK4a/Arf Deficiency Promote Aggressiveness of Pancreatic Cancer by Induction of EMT Consistent With Cancer Stem Cell Phenotype" by Wang et al. PMID: 27315162 Ref: ETS-Transcription Factor ETV1 Regulates Stromal Expansion and Metastasis in Pancreatic Cancer. PMID: 27318148 Ref: Synergistic reversal effect of epithelial-to-mesenchymal transition by miR-223 inhibitor and genistein in gemcitabine-resistant pancreatic cancer cells. PMID: 27429851 Ref: Hyperglycemia Promotes the Epithelial-Mesenchymal Transition of Pancreatic Cancer via Hydrogen Peroxide. PMID: 27433288 Ref: Oridonin inhibits pancreatic cancer cell migration and epithelial-mesenchymal transition by suppressing Wnt/beta-catenin signaling pathway. PMID: 27453691 Ref: Effect of PPM1H on malignant phenotype of human pancreatic cancer cells. PMID: 27599670 Ref: alpha-Mangostin-encapsulated PLGA nanoparticles inhibit pancreatic carcinogenesis by targeting cancer stem cells in human, and transgenic (Kras(G12D), and Kras(G12D)/tp53R270H) mice. PMID: 27624879 Ref: Nerve growth factor regulates CD133 function to promote tumor cell migration and invasion via activating ERK1/2 signaling in pancreatic cancer. PMID: 27654574 Ref: Targeting Epithelial-Mesenchymal Transition for Identification of Inhibitors for Pancreatic Cancer Cell Invasion and Tumor Spheres Formation. PMID: 27764163 Ref: Inhibition of NF-kappa B pathway leads to deregulation of epithelial-mesenchymal transition and neural invasion in pancreatic cancer. PMID: 27775688 Ref: Radiation promotes epithelial-to-mesenchymal transition and invasion of pancreatic cancer cell by activating carcinoma-associated fibroblasts. PMID: 27822411 Ref: Automated electrorotation shows electrokinetic separation of pancreatic cancer cells is robust to acquired chemotherapy resistance, serum starvation, and EMT. PMID: 27990211 Ref: The pattern of hMENA isoforms is regulated by TGF-beta1 in pancreatic cancer and may predict patient outcome. PMID: 28123868 |
Ref: Gedunin inhibits pancreatic cancer by altering sonic hedgehog signaling pathway. PMID: 26988754 Ref: Interleukin-17 promotes prostate cancer via MMP7-induced epithelial-to-mesenchymal transition. PMID: 27375020 Ref: ECM Composition and Rheology Regulate Growth, Motility, and Response to Photodynamic Therapy in 3D Models of Pancreatic Ductal Adenocarcinoma. PMID: 27671335 Ref: Upregulation of MicroRNA-935 Promotes the Malignant Behaviors of Pancreatic Carcinoma PANC-1 Cells via Targeting Inositol Polyphosphate 4-Phosphatase Type I Gene (INPP4A). PMID: 27733216 Ref: Prometastatic mechanisms of CAF-mediated EMT regulation in pancreatic cancer cells. PMID: 27878234 Ref: Oridonin inhibition and miR200b3p/ZEB1 axis in human pancreatic cancer. PMID: 27878247 Ref: TGFbeta promotes mesenchymal phenotype of pancreatic cancer cells, in part, through epigenetic activation of VAV1. PMID: 27893715 Ref: CDGSH Iron Sulfur Domain 2 Activates Proliferation and EMT of Pancreatic Cancer Cells via Wnt/beta-Catenin Pathway and Has Prognostic Value in Human Pancreatic Cancer. PMID: 27983920 Ref: Acriflavine Inhibits Acquired Drug Resistance by Blocking the Epithelial-to-Mesenchymal Transition and the Unfolded Protein Response. PMID: 27987431 Ref: Curcumin suppresses epithelial-to-mesenchymal transition and metastasis of pancreatic cancer cells by inhibiting cancer-associated fibroblasts. PMID: 28123853 Ref: Development of In Vitro Co-Culture Model in Anti-Cancer Drug Development Cascade. PMID: 28155598 Ref: The Aurora-A-Twist1 axis promotes highly aggressive phenotypes in pancreatic carcinoma. PMID: 28167680 Ref: Phosphorylation-dependent regulation of ALDH1A1 by Aurora kinase A: insights on their synergistic relationship in pancreatic cancer. PMID: 28193222 Ref: The mir-675-5p regulates the progression and development of pancreatic cancer via the UBQLN1-ZEB1-mir200 axis. PMID: 28212565 Ref: Thymidylate synthase is functionally associated with ZEB1 and contributes to the epithelial-to-mesenchymal transition of cancer cells. PMID: 28337746 Ref: Long Noncoding RNA PVT1 Promotes EMT and Cell Proliferation and Migration Through Downregulating p21 in Pancreatic Cancer Cells. PMID: 28355965 Ref: Histone deacetylase class-I inhibition promotes epithelial gene expression in pancreatic cancer cells in a BRD4- and MYC-dependent manner. PMID: 28369619 Ref: miR-202 Diminishes TGFbeta Receptors and Attenuates TGFbeta1-Induced EMT in Pancreatic Cancer. PMID: 28373289 Ref: CBX7 negatively regulates migration and invasion in glioma via Wnt/beta-catenin pathway inactivation. PMID: 28388562 Ref: Inhibition of Six1 affects tumour invasion and the expression of cancer stem cell markers in pancreatic cancer. PMID: 28388884 Ref: The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer. PMID: 28414315 Ref: Context-specific roles of EMT programmes in cancer cell dissemination. PMID: 28446813 Ref: Chemosensitization and inhibition of pancreatic cancer stem cell proliferation by overexpression of microRNA-205. PMID: 28536008 Ref: Long non-coding RNA TUG1 can promote proliferation and migration of pancreatic cancer via EMT pathway. PMID: 28617552 Ref: Upholding a role for EMT in pancreatic cancer metastasis. PMID: 28682339 Ref: EGFR-Targeted Cationic Polymeric Mixed Micelles for Codelivery of Gemcitabine and miR-205 for Treating Advanced Pancreatic Cancer. PMID: 28719220 Ref: A marginal anticancer effect of regorafenib on pancreatic carcinoma cells in vitro, ex vivo, and in vivo. PMID: 28779210 Ref: ITGA1 is a pre-malignant biomarker that promotes therapy resistance and metastatic potential in pancreatic cancer. PMID: 28855593 Ref: EMT and Treatment Resistance in Pancreatic Cancer. PMID: 28895920 Ref: Semaphorin 3 C drives epithelial-to-mesenchymal transition, invasiveness, and stem-like characteristics in prostate cells. PMID: 28904399 Ref: Kruppel-like factor 8 induces epithelial-to-mesenchymal transition and promotes invasion of pancreatic cancer cells through transcriptional activation of four and a half LIM-only protein 2. PMID: 28943967 Ref: Silencing IGFBP-2 decreases pancreatic cancer metastasis and enhances chemotherapeutic sensitivity. PMID: 28977895 Ref: miR-3656 expression enhances the chemosensitivity of pancreatic cancer to gemcitabine through modulation of the RHOF/EMT axis. PMID: 29048402 Ref: Tenascin-C induces migration and invasion through JNK/c-Jun signalling in pancreatic cancer. PMID: 29088796 Ref: Alternative polyadenylation of ZEB1 promotes its translation during genotoxic stress in pancreatic cancer cells. PMID: 29120411 Ref: Long noncoding RNA NORAD, a novel competing endogenous RNA, enhances the hypoxia-induced epithelial-mesenchymal transition to promote metastasis in pancreatic cancer. PMID: 29121972 Ref: [Bit1 mediates the malignant behaviors in pancreatic cancer and its potential clinical significance]. PMID: 29136735 Ref: miR-135b-5p Promotes migration, invasion and EMT of pancreatic cancer cells by targeting NR3C2. PMID: 29196101 Ref: 5-FU resistant EMT-like pancreatic cancer cells are hypersensitive to photochemical internalization of the novel endoglin-targeting immunotoxin CD105-saporin. PMID: 29258566 Ref: Aberrant expression of STYK1 and E-cadherin confer a poor prognosis for pancreatic cancer patients. PMID: 29340057 |
Ref: Targeting integrin-linked kinase to suppress oncogenic KRAS signaling in pancreatic cancer. PMID: 27936345 Ref: The inhibitory effect of 5,7-DMF on pancreatic sphere-forming cell function mediated by FoxM1 gene expression. PMID: 28802012 Ref: TOP2A induces malignant character of pancreatic cancer through activating beta-catenin signaling pathway. PMID: 29045811 Ref: Adipocytes sustain pancreatic cancer progression through a non-canonical WNT paracrine network inducing ROR2 nuclear shuttling. PMID: 29151594 Ref: Pseudolaric Acid B Inhibits Proliferation, Invasion and Epithelial-to-Mesenchymal Transition in Human Pancreatic Cancer Cell. PMID: 29214772 Ref: Microfluidic co-culture of pancreatic tumor spheroids with stellate cells as a novel 3D model for investigation of stroma-mediated cell motility and drug resistance. PMID: 29329547 Ref: Phosphoglycerate Mutase 1 (PGAM1) Promotes Pancreatic Ductal Adenocarcinoma (PDAC) Metastasis by Acting as a Novel Downstream Target of the PI3K/Akt/mTOR Pathway. PMID: 29386088 Ref: Prognostic significance of E-cadherin and ZEB1 expression in intraductal papillary mucinous neoplasm. PMID: 29416615 Ref: The role of cancer-associated fibroblast MRC-5 in pancreatic cancer. PMID: 29483967 Ref: Kruppel-Like Factor 4 Inhibits Pancreatic Cancer Epithelial-to-Mesenchymal Transition and Metastasis by Down-Regulating Caveolin-1 Expression. PMID: 29587259 Ref: MEKK3 Sustains EMT and Stemness in Pancreatic Cancer by Regulating YAP and TAZ Transcriptional Activity. PMID: 29599309 Ref: Leptin-Notch axis impairs 5-fluorouracil effects on pancreatic cancer. PMID: 29719602 Ref: Conversion of epithelial-to-mesenchymal transition to mesenchymal-to-epithelial transition is mediated by oxygen concentration in pancreatic cancer cells. PMID: 29731878 Ref: A receptor tyrosine kinase ROR1 inhibitor (KAN0439834) induced significant apoptosis of pancreatic cells which was enhanced by erlotinib and ibrutinib. PMID: 29856777 Ref: Overexpression of MIST1 reverses the epithelial-mesenchymal transition and reduces the tumorigenicity of pancreatic cancer cells via the Snail/E-cadherin pathway. PMID: 29859299 Ref: Linc00462 promotes pancreatic cancer invasiveness through the miR-665/TGFBR1-TGFBR2/SMAD2/3 pathway. PMID: 29899418 Ref: EMT in Metastasis: Finding the Right Balance. PMID: 29920271 Ref: Clinical Implications of Lysyl Oxidase-Like Protein 2 Expression in Pancreatic Cancer. PMID: 29959362 Ref: Knockdown of FUT3 disrupts the proliferation, migration, tumorigenesis and TGF-beta induced EMT in pancreatic cancer cells. PMID: 29963165 Ref: Long non-coding RNA lnc-PCTST predicts prognosis through inhibiting progression of pancreatic cancer by downregulation of TACC-3. PMID: 29978472 Ref: Overexpression of PEAK1 contributes to epithelial-mesenchymal transition and tumor metastasis in lung cancer through modulating ERK1/2 and JAK2 signaling. PMID: 30038287 Ref: MiR-361-3p regulates ERK1/2-induced EMT via DUSP2 mRNA degradation in pancreatic ductal adenocarcinoma. PMID: 30042387 Ref: TGF-betaRII Knock-down in Pancreatic Cancer Cells Promotes Tumor Growth and Gemcitabine Resistance. Importance of STAT3 Phosphorylation on S727. PMID: 30065235 Ref: Targeting S1PR1/STAT3 loop abrogates desmoplasia and chemosensitizes pancreatic cancer to gemcitabine. PMID: 30083262 Ref: Long non-coding RNA HOTAIR promotes tumorigenesis and forecasts a poor prognosis in cholangiocarcinoma. PMID: 30111807 Ref: Dual reporter genetic mouse models of pancreatic cancer identify an epithelial-to-mesenchymal transition-independent metastasis program. PMID: 30120146 Ref: Human Surfactant Protein D Suppresses Epithelial-to-Mesenchymal Transition in Pancreatic Cancer Cells by Downregulating TGF-beta. PMID: 30158928 Ref: Overexpression of GP73 promotes cell invasion, migration and metastasis by inducing epithelial-mesenchymal transition in pancreatic cancer. PMID: 30217697 Ref: TGFbeta-activated USP27X deubiquitinase regulates cell migration and chemoresistance via stabilization of Snail1. PMID: 30341066 |