Primary Site >> Colorectal Cancer

Gene >> ITGA4

Journal: Cell Regul. 1991 May;2(5):347-55.
Title: Tumor cell surface alpha 4 beta 1 integrin mediates adhesion to vascular endothelium: demonstration of an interaction with the N-terminal domains of INCAM-110/VCAM-1.
Author: Taichman, D B|Cybulsky, M I|Djaffar, I|Longenecker, B M|Teixido, J|Rice, G E|Aruffo, A|Bevilacqua, M P
PMID: 1716464
Journal: J Biol Chem. 1998 Jan 16;273(3):1662-9.
Title: Disruption of fibronectin binding to the alpha 5 beta 1 integrin stimulates the expression of cyclin-dependent kinases and DNA synthesis through activation of extracellular signal-regulated kinase.
Author: Gong, J|Ko, T C|Brattain, M G
PMID: 9430710
Journal: J Surg Res. 1998 Jul 15;78(1):78-84.
Title: Enhancement of metastatic activity of colon cancer as influenced by expression of cell surface antigens.
Author: Okazaki, K|Nakayama, Y|Shibao, K|Hirata, K|Nagata, N|Itoh, H
PMID: 9733622
Journal: J Gastroenterol. 1999 Jun;34(3):327-33.
Title: Functional expression of beta1 and beta2 integrins on tumor infiltrating lymphocytes (TILs) in colorectal cancer.
Author: Kitayama, J|Nagawa, H|Nakayama, H|Tuno, N|Shibata, Y|Muto, T
PMID: 10433007
Journal: Ann Surg Oncol. 1999 Jul-Aug;6(5):500-6.
Title: Functional down-regulation of beta1 and beta2 integrins of lamina propria lymphocytes (LPL) and tumor-infiltrating lymphocytes (TIL) in colorectal cancer patients.
Author: Kitayama, J|Tuno, N|Nakayama, H|Shibata, Y|Muto, T|Nagawa, H
PMID: 10458690
Journal: Ai Zheng. 2003 Jul;22(7):758-61.
Title: [Determination of four kinds of cell phenotypes of peripheral blood lymphocytes in patients with colorectal cancer].
Author: Chen, Teng|Shi, Jing-Hua|Zhao, Rong-Hua|Li, Hua-Bao|Li, Li
PMID: 12866971
Journal: Proteomics. 2006 Mar;6(6):1791-802.
Title: Multiplex detection of surface molecules on colorectal cancers.
Author: Ellmark, Peter|Belov, Larissa|Huang, Pauline|Lee, C Soon|Solomon, Michael J|Morgan, Daniel K|Christopherson, Richard I
PMID: 16485257
Journal: Recent Pat DNA Gene Seq. 2010 Jun;4(2):86-93.
Title: Recent patents and advances in genomic biomarker discovery for colorectal cancers.
Author: Quyun, Chen|Ye, Zhiyun|Lin, Sheng-Cai|Lin, Biaoyang
PMID: 20426761
Journal: Hepatogastroenterology. 2010 Jul-Aug;57(101):720-7.
Title: Detection of colorectal neoplasm using promoter methylation of ITGA4, SFRP2, and p16 in stool samples: a preliminary report in Korean patients.
Author: Chang, Eugene|Park, Dong Il|Kim, Young Jin|Kim, Bo Kyoung|Park, Jung Ho|Kim, Hong Joo|Cho, Yong Kyun|Sohn, Chong Il|Jeon, Woo Kyu|Kim, Byung Ik|Kim, Hung Dai|Kim, Dong Hoon|Kim, Young Ho
PMID: 21033217
Journal: Clin Transl Gastroenterol. 2012 Dec 6;3:e27.
Title: A tissue-based comparative effectiveness analysis of biomarkers for early detection of colorectal tumors.
Author: Ahmed, Deeqa|Danielsen, Stine A|Aagesen, Trude H|Bretthauer, Michael|Thiis-Evensen, Espen|Hoff, Geir|Rognum, Torleiv O|Nesbakken, Arild|Lothe, Ragnhild A|Lind, Guro E
PMID: 23324654
Journal: J Immunol Methods. 2015 Jan;416:59-68.
Title: Surface profiles of live colorectal cancer cells and tumor infiltrating lymphocytes from surgical samples correspond to prognostic categories.
Author: Zhou, Jerry|Belov, Larissa|Chapuis, Pierre|Chan, Charles|Armstrong, Nicola|Kaufman, Kimberley L|Solomon, Michael J|Clarke, Stephen J|Christopherson, Richard I
PMID: 25445327
Journal: Pharmacogenomics J. 2015 Jun;15(3):226-34.
Title: Integrin genetic variants and stage-specific tumor recurrence in patients with stage II and III colon cancer.
Author: Bohanes, P|Yang, D|Loupakis, F|LaBonte, M J|Gerger, A|Ning, Y|Lenz, C|Lenz, F|Wakatsuki, T|Zhang, W|Benhaim, L|El-Khoueiry, A|El-Khoueiry, R|Lenz, H-J
PMID: 25487679
Journal: World J Gastroenterol. 2015 Mar 7;21(9):2629-37.
Title: Combined detection of plasma GATA5 and SFRP2 methylation is a valid noninvasive biomarker for colorectal cancer and adenomas.
Author: Zhang, Xie|Song, Yu-Fei|Lu, Hong-Na|Wang, Dan-Ping|Zhang, Xue-Song|Huang, Shi-Liang|Sun, Bei-Lei|Huang, Zhi-Gang
PMID: 25759530
Journal: J Cancer Res Clin Oncol. 2015 Dec;141(12):2097-107.
Title: Hypermethylation of ITGA4, TFPI2 and VIMENTIN promoters is increased in inflamed colon tissue: putative risk markers for colitis-associated cancer.
Author: Gerecke, Christian|Scholtka, Bettina|Lowenstein, Yvonne|Fait, Isabel|Gottschalk, Uwe|Rogoll, Dorothee|Melcher, Ralph|Kleuser, Burkhard
PMID: 25902909
Journal: PLoS One. 2016 Apr 25;11(4):e0153125.
Title: Aberrant DNA Methylation: Implications in Racial Health Disparity.
Author: Wang, Xuefeng|Ji, Ping|Zhang, Yuanhao|LaComb, Joseph F|Tian, Xinyu|Li, Ellen|Williams, Jennie L
PMID: 27111221
Journal: Biochim Biophys Acta. 2016 Aug;1866(1):106-20.
Title: DNA methylation based biomarkers in colorectal cancer: A systematic review.
Author: Lam, Kevin|Pan, Kathy|Linnekamp, Janneke Fiona|Medema, Jan Paul|Kandimalla, Raju
PMID: 27385266
Journal: Gut. 2017 Oct 5. pii: gutjnl-2016-313372.
Title: Discovery of methylated circulating DNA biomarkers for comprehensive non-invasive monitoring of treatment response in metastatic colorectal cancer.
Author: Barault, Ludovic|Amatu, Alessio|Siravegna, Giulia|Ponzetti, Agostino|Moran, Sebastian|Cassingena, Andrea|Mussolin, Benedetta|Falcomata, Chiara|Binder, Alexandra M|Cristiano, Carmen|Oddo, Daniele|Guarrera, Simonetta|Cancelliere, Carlotta|Bustreo, Sara|Benc
PMID: 28982739
Journal: Mol Carcinog. 2018 Feb;57(2):243-261.
Title: The PI3K/AKT signaling pathway: Associations of miRNAs with dysregulated gene expression in colorectal cancer.
Author: Slattery, Martha L|Mullany, Lila E|Sakoda, Lori C|Wolff, Roger K|Stevens, John R|Samowitz, Wade S|Herrick, Jennifer S
PMID: 29068474