Primary Site >> Colorectal Cancer

Gene >> ITGA4

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Ref: Tumor cell surface alpha 4 beta 1 integrin mediates adhesion to vascular endothelium: demonstration of an interaction with the N-terminal domains of INCAM-110/VCAM-1.
PMID: 1716464
Ref: Disruption of fibronectin binding to the alpha 5 beta 1 integrin stimulates the expression of cyclin-dependent kinases and DNA synthesis through activation of extracellular signal-regulated kinase.
PMID: 9430710
Ref: Enhancement of metastatic activity of colon cancer as influenced by expression of cell surface antigens.
PMID: 9733622
Ref: Functional expression of beta1 and beta2 integrins on tumor infiltrating lymphocytes (TILs) in colorectal cancer.
PMID: 10433007
Ref: Functional down-regulation of beta1 and beta2 integrins of lamina propria lymphocytes (LPL) and tumor-infiltrating lymphocytes (TIL) in colorectal cancer patients.
PMID: 10458690
Ref: [Determination of four kinds of cell phenotypes of peripheral blood lymphocytes in patients with colorectal cancer].
PMID: 12866971
Ref: Multiplex detection of surface molecules on colorectal cancers.
PMID: 16485257
Ref: Recent patents and advances in genomic biomarker discovery for colorectal cancers.
PMID: 20426761
Ref: Detection of colorectal neoplasm using promoter methylation of ITGA4, SFRP2, and p16 in stool samples: a preliminary report in Korean patients.
PMID: 21033217
Ref: A tissue-based comparative effectiveness analysis of biomarkers for early detection of colorectal tumors.
PMID: 23324654
Ref: Surface profiles of live colorectal cancer cells and tumor infiltrating lymphocytes from surgical samples correspond to prognostic categories.
PMID: 25445327
Ref: Integrin genetic variants and stage-specific tumor recurrence in patients with stage II and III colon cancer.
PMID: 25487679
Ref: Combined detection of plasma GATA5 and SFRP2 methylation is a valid noninvasive biomarker for colorectal cancer and adenomas.
PMID: 25759530
Ref: Hypermethylation of ITGA4, TFPI2 and VIMENTIN promoters is increased in inflamed colon tissue: putative risk markers for colitis-associated cancer.
PMID: 25902909
Ref: Aberrant DNA Methylation: Implications in Racial Health Disparity.
PMID: 27111221
Ref: DNA methylation based biomarkers in colorectal cancer: A systematic review.
PMID: 27385266
Ref: Discovery of methylated circulating DNA biomarkers for comprehensive non-invasive monitoring of treatment response in metastatic colorectal cancer.
PMID: 28982739
Ref: The PI3K/AKT signaling pathway: Associations of miRNAs with dysregulated gene expression in colorectal cancer.
PMID: 29068474