Primary Site >> Colorectal Cancer
Gene >> IRS2
| 1. | |||||||||||
| Journal: | Cancer Epidemiol Biomarkers Prev. 2004 Jul;13(7):1206-14. | ||||||||||
| Title: | Associations among IRS1, IRS2, IGF1, and IGFBP3 genetic polymorphisms and colorectal cancer. | ||||||||||
| Author: | Slattery, Martha L|Samowitz, Wade|Curtin, Karen|Ma, Khe Ni|Hoffman, Michael|Caan, Bette|Neuhausen, Susan | ||||||||||
| PMID: | 15247132 | ||||||||||
| 2. | |||||||||||
| Journal: | Cancer Epidemiol Biomarkers Prev. 2004 Apr;13(4):538-45. | ||||||||||
| Title: | Aspirin, NSAIDs, and colorectal cancer: possible involvement in an insulin-related pathway. | ||||||||||
| Author: | Slattery, Martha L|Samowitz, Wade|Hoffman, Michael|Ma, Khi Ne|Levin, Theodore R|Neuhausen, Susan | ||||||||||
| PMID: | 15066917 | ||||||||||
| 3. | |||||||||||
| Journal: | Int J Cancer. 2005 May 20;115(1):148-54. | ||||||||||
| Title: | Energy balance, insulin-related genes and risk of colon and rectal cancer. | ||||||||||
| Author: | Slattery, Martha L|Murtaugh, Maureen|Caan, Bette|Ma, Khe Ni|Neuhausen, Susan|Samowitz, Wade | ||||||||||
| PMID: | 15688407 | ||||||||||
| 4. | |||||||||||
| Journal: | Mutat Res. 2006 Mar 20;595(1-2):117-24. | ||||||||||
| Title: | Polymorphisms in insulin-related genes predispose to specific KRAS2 and TP53 mutations in colon cancer. | ||||||||||
| Author: | Samowitz, Wade S|Wolff, Roger K|Ma, Khe Ni|Andersen, Kristen|Caan, Bette|Slattery, Martha L | ||||||||||
| PMID: | 16448675 | ||||||||||
| 5. | |||||||||||
| Journal: | Cancer Causes Control. 2006 Apr;17(3):239-49. | ||||||||||
| Title: | PPARgamma and colon and rectal cancer: associations with specific tumor mutations, aspirin, ibuprofen and insulin-related genes (United States). | ||||||||||
| Author: | Slattery, Martha L|Curtin, Karen|Wolff, Roger|Ma, Khe Ni|Sweeney, Carol|Murtaugh, Maureen|Potter, John D|Levin, Theodore R|Samowitz, Wade | ||||||||||
| PMID: | 16489531 | ||||||||||
| 6. | |||||||||||
| Journal: | Cancer Epidemiol Biomarkers Prev. 2007 Apr;16(4):703-8. | ||||||||||
| Title: | Insulin resistance-related genes and advanced left-sided colorectal adenoma. | ||||||||||
| Author: | Gunter, Marc J|Hayes, Richard B|Chatterjee, Nilanjan|Yeager, Meredith|Welch, Robert|Schoen, Robert E|Yakochi, Lance|Schatzkin, Arthur|Peters, Ulrike | ||||||||||
| PMID: | 17416760 | ||||||||||
| 7. | |||||||||||
| Journal: | Endocr Relat Cancer. 2007 Sep;14(3):733-40. | ||||||||||
| Title: | Insulin pathway related genes and risk of colorectal cancer: INSR promoter polymorphism shows a protective effect. | ||||||||||
| Author: | Pechlivanis, Sonali|Pardini, Barbara|Bermejo, Justo Lorenzo|Wagner, Kerstin|Naccarati, Alessio|Vodickova, Ludmila|Novotny, Jan|Hemminki, Kari|Vodicka, Pavel|Forsti, Asta | ||||||||||
| PMID: | 17914103 | ||||||||||
| 8. | |||||||||||
| Journal: | Int J Cancer. 2008 Apr 1;122(7):1611-7. | ||||||||||
| Title: | Leptin and leptin receptor genotypes and colon cancer: gene-gene and gene-lifestyle interactions. | ||||||||||
| Author: | Slattery, Martha L|Wolff, Roger K|Herrick, Jennifer|Caan, Bette J|Potter, John D | ||||||||||
| PMID: | 18059035 | ||||||||||
| 9. | |||||||||||
| Journal: | Mol Cancer Ther. 2009 Aug;8(8):2110-21. | ||||||||||
| Title: | Molecular predictors of response to a humanized anti-insulin-like growth factor-I receptor monoclonal antibody in breast and colorectal cancer. | ||||||||||
| Author: | Zha, Jiping|O'Brien, Carol|Savage, Heidi|Huw, Ling-Yuh|Zhong, Fiona|Berry, Leanne|Lewis Phillips, Gail D|Luis, Elizabeth|Cavet, Guy|Hu, Xiaolan|Amler, Lukas C|Lackner, Mark R | ||||||||||
| PMID: | 19671761 | ||||||||||
| 10. | |||||||||||
| Journal: | PLoS One. 2012;7(10):e46716. | ||||||||||
| Title: | Cytosolic malic enzyme 1 (ME1) mediates high fat diet-induced adiposity, endocrine profile, and gastrointestinal tract proliferation-associated biomarkers in male mice. | ||||||||||
| Author: | Al-Dwairi, Ahmed|Pabona, John Mark P|Simmen, Rosalia C M|Simmen, Frank A | ||||||||||
| PMID: | 23056418 | ||||||||||
| 11. | |||||||||||
| Journal: | Asian Pac J Cancer Prev. 2013;14(9):5011-6. | ||||||||||
| Title: | Is there an association between variants in candidate insulin pathway genes IGF-I, IGFBP-3, INSR, and IRS2 and risk of colorectal cancer in the Iranian population? | ||||||||||
| Author: | Karimi, Khatoon|Mahmoudi, Touraj|Karimi, Negar|Dolatmoradi, Hesamodin|Arkani, Maral|Farahani, Hamid|Vahedi, Mohsen|Parsimehr, Elham|Dabiri, Reza|Nobakht, Hossein|Asadi, Asadollah|Zali, Mohammad Reza | ||||||||||
| PMID: | 24175768 | ||||||||||
| 12. | |||||||||||
| Journal: | Mol Cancer Ther. 2013 Dec;12(12):2929-39. | ||||||||||
| Title: | Molecular predictors of sensitivity to the insulin-like growth factor 1 receptor inhibitor Figitumumab (CP-751,871). | ||||||||||
| Author: | Pavlicek, Adam|Lira, Maruja E|Lee, Nathan V|Ching, Keith A|Ye, Jingjing|Cao, Joan|Garza, Scott J|Hook, Kenneth E|Ozeck, Mark|Shi, Stephanie T|Yuan, Jing|Zheng, Xianxian|Rejto, Paul A|Kan, Julie L C|Christensen, James G | ||||||||||
| PMID: | 24107449 | ||||||||||
| 13. | |||||||||||
| Journal: | Oncol Rep. 2013 Oct;30(4):1553-60. | ||||||||||
| Title: | Novel insulin receptor substrate 1 and 2 variants in breast and colorectal cancer. | ||||||||||
| Author: | Esposito, Diana Liberata|Verginelli, Fabio|Toracchio, Sonia|Mammarella, Sandra|De Lellis, Laura|Vanni, Cinzia|Russo, Antonio|Mariani-Costantini, Renato|Cama, Alessandro | ||||||||||
| PMID: | 23877285 | ||||||||||
| 14. | |||||||||||
| Journal: | Int J Exp Pathol. 2013 Jun;94(3):203-11. | ||||||||||
| Title: | IRS2 is a candidate driver oncogene on 13q34 in colorectal cancer. | ||||||||||
| Author: | Day, Elizabeth|Poulogiannis, George|McCaughan, Frank|Mulholland, Shani|Arends, Mark J|Ibrahim, Ashraf E K|Dear, Paul H | ||||||||||
| PMID: | 23594372 | ||||||||||
| 15. | |||||||||||
| Journal: | PLoS One. 2014 Jan 30;9(1):e86911. | ||||||||||
| Title: | Lack of association between insulin receptor substrate2 rs1805097 polymorphism and the risk of colorectal and breast cancer: a meta-analysis. | ||||||||||
| Author: | Hu, Yue|Zhou, Min|Zhang, Kai|Kong, Xiangquan|Hu, Xiaoyan|Li, Kang|Liu, Li | ||||||||||
| PMID: | 24497996 | ||||||||||
| 16. | |||||||||||
| Journal: | Prz Gastroenterol. 2014;9(2):88-92. | ||||||||||
| Title: | IRS-2 G1057D polymorphism in Turkish patients with colorectal cancer. | ||||||||||
| Author: | Yukseloglu, Emel Hulya|Celik, Sevim Karakas|Kucuk, Meral Urhan|Yalin, Erdinc|Ozkal, S Sebnem|Ates, Cengiz|Berkoz, Mehmet|Yalin, Serap|Ates, Nurcan Aras | ||||||||||
| PMID: | 25061488 | ||||||||||
| 17. | |||||||||||
| Journal: | Cancer Res. 2014 Dec 1;74(23):6784-95. | ||||||||||
| Title: | MHC-restricted phosphopeptides from insulin receptor substrate-2 and CDC25b offer broad-based immunotherapeutic agents for cancer. | ||||||||||
| Author: | Zarling, Angela L|Obeng, Rebecca C|Desch, A Nicole|Pinczewski, Joel|Cummings, Kara L|Deacon, Donna H|Conaway, Mark|Slingluff, Craig L Jr|Engelhard, Victor H | ||||||||||
| PMID: | 25297629 | ||||||||||
| 18. | |||||||||||
| Journal: | Mol Cancer Ther. 2015 Feb;14(2):620-30. | ||||||||||
| Title: | IRS2 copy number gain, KRAS and BRAF mutation status as predictive biomarkers for response to the IGF-1R/IR inhibitor BMS-754807 in colorectal cancer cell lines. | ||||||||||
| Author: | Huang, Fei|Chang, Han|Greer, Ann|Hillerman, Stephen|Reeves, Karen A|Hurlburt, Warren|Cogswell, John|Patel, Dharmesh|Qi, Zhenhao|Fairchild, Craig|Ryseck, Rolf-Peter|Wong, Tai W|Finckenstein, Friedrich G|Jackson, Jeffrey|Carboni, Joan M | ||||||||||
| PMID: | 25527633 | ||||||||||
| 19. | |||||||||||
| Journal: | Tumour Biol. 2015 May;36(5):3709-15. | ||||||||||
| Title: | An exon variant in insulin receptor gene is associated with susceptibility to colorectal cancer in women. | ||||||||||
| Author: | Mahmoudi, Touraj|Majidzadeh-A, Keivan|Karimi, Khatoon|Karimi, Negar|Farahani, Hamid|Dabiri, Reza|Nobakht, Hossein|Dolatmoradi, Hesamodin|Arkani, Maral|Zali, Mohammad Reza | ||||||||||
| PMID: | 25557790 | ||||||||||
| 20. | |||||||||||
| Journal: | Mol Cell Biol. 2015 Mar;35(6):988-1000. | ||||||||||
| Title: | Role of microRNA 30a targeting insulin receptor substrate 2 in colorectal tumorigenesis. | ||||||||||
| Author: | Zhang, Qian|Tang, Qingchao|Qin, Dandan|Yu, Lei|Huang, Rui|Lv, Guixiang|Zou, Zhaoxia|Jiang, Xiao-chen|Zou, Chendan|Liu, Wei|Luo, Jing|Zhao, Zhixun|Muhammad, Shan|Wang, Guiyu|Chen, Ying-gang|Wang, Xishan | ||||||||||
| PMID: | 25582198 | ||||||||||
| 21. | |||||||||||
| Journal: | Cancer Res. 2015 Apr 15;75(8):1560-6. | ||||||||||
| Title: | Evaluating patient-derived colorectal cancer xenografts as preclinical models by comparison with patient clinical data. | ||||||||||
| Author: | Nunes, Manoel|Vrignaud, Patricia|Vacher, Sophie|Richon, Sophie|Lievre, Astrid|Cacheux, Wulfran|Weiswald, Louis-Bastien|Massonnet, Gerald|Chateau-Joubert, Sophie|Nicolas, Andre|Dib, Colette|Zhang, Weidong|Watters, James|Bergstrom, Donald|Roman-Roman, Sergi | ||||||||||
| PMID: | 25712343 | ||||||||||
| 22. | |||||||||||
| Journal: | Hum Pathol. 2015 May;46(5):753-60. | ||||||||||
| Title: | Frameshift mutations in mammalian target of rapamycin pathway genes and their regional heterogeneity in sporadic colorectal cancers. | ||||||||||
| Author: | Choi, Mi Ryoung|Yoo, Nam Jin|An, Chang Hyeok|Lee, Sug Hyung | ||||||||||
| PMID: | 25776026 | ||||||||||
| 23. | |||||||||||
| Journal: | Nature. 2015 Oct 8;526(7572):263-7. | ||||||||||
| Title: | The genomic landscape of response to EGFR blockade in colorectal cancer. | ||||||||||
| Author: | Bertotti, Andrea|Papp, Eniko|Jones, Sian|Adleff, Vilmos|Anagnostou, Valsamo|Lupo, Barbara|Sausen, Mark|Phallen, Jillian|Hruban, Carolyn A|Tokheim, Collin|Niknafs, Noushin|Nesselbush, Monica|Lytle, Karli|Sassi, Francesco|Cottino, Francesca|Migliardi, Giorg | ||||||||||
| PMID: | 26416732 | ||||||||||
| 24. | |||||||||||
| Journal: | Oncotarget. 2016 Jul 26;7(30):47699-47710. | ||||||||||
| Title: | BRAFV600E-dependent Mcl-1 stabilization leads to everolimus resistance in colon cancer cells. | ||||||||||
| Author: | He, Kan|Chen, Dongshi|Ruan, Hang|Li, Xiangyun|Tong, Jingshan|Xu, Xiang|Zhang, Lin|Yu, Jian | ||||||||||
| PMID: | 27351224 | ||||||||||
| 25. | |||||||||||
| Journal: | Oncotarget. 2017 Apr 11;8(15):25107-25114. | ||||||||||
| Title: | IRS-2 rs1805097 polymorphism is associated with the decreased risk of colorectal cancer. | ||||||||||
| Author: | Yin, Jiefeng|Zhang, Zhe|Zheng, Huajun|Xu, Lei | ||||||||||
| PMID: | 28212577 | ||||||||||
| 26. | |||||||||||
| Journal: | Int J Cancer. 2017 Jun 15;140(12):2648-2656. | ||||||||||
| Title: | Dietary glycemic and insulin scores and colorectal cancer survival by tumor molecular biomarkers. | ||||||||||
| Author: | Keum, NaNa|Yuan, Chen|Nishihara, Reiko|Zoltick, Emilie|Hamada, Tsuyoshi|Martinez Fernandez, Alejandro|Zhang, Xuehong|Hanyuda, Akiko|Liu, Li|Kosumi, Keisuke|Nowak, Jonathan A|Jhun, Iny|Soong, T Rinda|Morikawa, Teppei|Tabung, Fred K|Qian, Zhi Rong|Fuchs, Ch | ||||||||||
| PMID: | 28268248 | ||||||||||