Primary Site >> Pancreatic Cancer
Gene >> IRS1
| 1. | |||||||||||
| Journal: | Int J Oncol. 1996 Sep;9(3):487-92. | ||||||||||
| Title: | Insulin-like growth factor II activates mitogenic signaling in pancreatic cancer cells via IRS-1. | ||||||||||
| Author: | Bergmann, U|Funatomi, H|Kornmann, M|Ishiwata, T|Beger, H|Korc, M | ||||||||||
| PMID: | 21541539 | ||||||||||
| 2. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 1996 Mar 27;220(3):886-90. | ||||||||||
| Title: | Increased expression of insulin receptor substrate-1 in human pancreatic cancer. | ||||||||||
| Author: | Bergmann, U|Funatomi, H|Kornmann, M|Beger, H G|Korc, M | ||||||||||
| PMID: | 8607861 | ||||||||||
| 3. | |||||||||||
| Journal: | Br J Cancer. 2005 Mar 14;92(5):921-8. | ||||||||||
| Title: | Interleukin-4 enhances proliferation of human pancreatic cancer cells: evidence for autocrine and paracrine actions. | ||||||||||
| Author: | Prokopchuk, O|Liu, Y|Henne-Bruns, D|Kornmann, M | ||||||||||
| PMID: | 15714203 | ||||||||||
| 4. | |||||||||||
| Journal: | Cancer Res. 2005 Oct 15;65(20):9164-8. | ||||||||||
| Title: | Insulin receptor substrate is a mediator of phosphoinositide 3-kinase activation in quiescent pancreatic cancer cells. | ||||||||||
| Author: | Asano, Takayuki|Yao, Yixin|Shin, Sonyo|McCubrey, James|Abbruzzese, James L|Reddy, Shrikanth A G | ||||||||||
| PMID: | 16230374 | ||||||||||
| 5. | |||||||||||
| Journal: | Cancer Res. 2007 Sep 15;67(18):8856-64. | ||||||||||
| Title: | RAV12 accelerates the desensitization of Akt/PKB pathway of insulin-like growth factor I receptor signaling in COLO205. | ||||||||||
| Author: | Li, Jonathan Chi-Hang|Li, Ronghao | ||||||||||
| PMID: | 17875727 | ||||||||||
| 6. | |||||||||||
| Journal: | Eur J Cancer. 2008 Jul;44(11):1577-86. | ||||||||||
| Title: | Inhibition of insulin-like growth factor-I receptor (IGF-IR) using NVP-AEW541, a small molecule kinase inhibitor, reduces orthotopic pancreatic cancer growth and angiogenesis. | ||||||||||
| Author: | Moser, Christian|Schachtschneider, Philipp|Lang, Sven A|Gaumann, Andreas|Mori, Akira|Zimmermann, Johann|Schlitt, Hans J|Geissler, Edward K|Stoeltzing, Oliver | ||||||||||
| PMID: | 18445520 | ||||||||||
| 7. | |||||||||||
| Journal: | Cancer Res. 2009 Feb 15;69(4):1350-7. | ||||||||||
| Title: | Insulin receptor substrate-2 mediated insulin-like growth factor-I receptor overexpression in pancreatic adenocarcinoma through protein kinase Cdelta. | ||||||||||
| Author: | Kwon, Junhye|Stephan, Susann|Mukhopadhyay, Ananya|Muders, Michael H|Dutta, Shamit K|Lau, Julie S|Mukhopadhyay, Debabrata | ||||||||||
| PMID: | 19190347 | ||||||||||
| 8. | |||||||||||
| Journal: | Front Biosci (Landmark Ed). 2009 Jan 1;14:2170-80. | ||||||||||
| Title: | 2-Methoxyestradiol mediated signaling network in pancreatic cancer. | ||||||||||
| Author: | Basu, Aruna|Haldar, Subrata | ||||||||||
| PMID: | 19273191 | ||||||||||
| 9. | |||||||||||
| Journal: | Mol Cancer Res. 2010 Aug;8(8):1152-63. | ||||||||||
| Title: | Nitric oxide inhibits the proliferation and invasion of pancreatic cancer cells through degradation of insulin receptor substrate-1 protein. | ||||||||||
| Author: | Sugita, Hiroki|Kaneki, Masao|Furuhashi, Satoshi|Hirota, Masahiko|Takamori, Hiroshi|Baba, Hideo | ||||||||||
| PMID: | 20663861 | ||||||||||
| 10. | |||||||||||
| Journal: | Gastroenterology. 2010 Aug;139(2):464-73, 473.e1-3. | ||||||||||
| Title: | Insulin-like growth factor axis gene polymorphisms and clinical outcomes in pancreatic cancer. | ||||||||||
| Author: | Dong, Xiaoqun|Javle, Milind|Hess, Kenneth R|Shroff, Rachna|Abbruzzese, James L|Li, Donghui | ||||||||||
| PMID: | 20416304 | ||||||||||
| 11. | |||||||||||
| Journal: | Cancer Epidemiol. 2012 Apr;36(2):206-11. | ||||||||||
| Title: | Insulin-like growth factor axis gene polymorphisms modify risk of pancreatic cancer. | ||||||||||
| Author: | Dong, Xiaoqun|Li, Yanan|Tang, Hongwei|Chang, Ping|Hess, Kenneth R|Abbruzzese, James L|Li, Donghui | ||||||||||
| PMID: | 21852217 | ||||||||||
| 12. | |||||||||||
| Journal: | Clin Cancer Res. 2012 May 15;18(10):2838-49. | ||||||||||
| Title: | Molecular profiling of pancreatic neuroendocrine tumors in sporadic and Von Hippel-Lindau patients. | ||||||||||
| Author: | Speisky, Daniela|Duces, Aurelie|Bieche, Ivan|Rebours, Vinciane|Hammel, Pascal|Sauvanet, Alain|Richard, Stephane|Bedossa, Pierre|Vidaud, Michel|Murat, Arnaud|Niccoli, Patricia|Scoazec, Jean-Yves|Ruszniewski, Philippe|Couvelard, Anne | ||||||||||
| PMID: | 22461457 | ||||||||||
| 13. | |||||||||||
| Journal: | BMC Cancer. 2013 May 10;13:235. | ||||||||||
| Title: | Metformin-mediated growth inhibition involves suppression of the IGF-I receptor signalling pathway in human pancreatic cancer cells. | ||||||||||
| Author: | Karnevi, Emelie|Said, Katarzyna|Andersson, Roland|Rosendahl, Ann H | ||||||||||
| PMID: | 23663483 | ||||||||||
| 14. | |||||||||||
| Journal: | J Biol Chem. 2014 Aug 1;289(31):21694-705. | ||||||||||
| Title: | The prolyl peptidases PRCP/PREP regulate IRS-1 stability critical for rapamycin-induced feedback activation of PI3K and AKT. | ||||||||||
| Author: | Duan, Lei|Ying, Guoguang|Danzer, Brian|Perez, Ricardo E|Shariat-Madar, Zia|Levenson, Victor V|Maki, Carl G | ||||||||||
| PMID: | 24936056 | ||||||||||
| 15. | |||||||||||
| Journal: | PLoS One. 2015 Jan 21;10(1):e0116869. | ||||||||||
| Title: | A genome-wide investigation of microRNA expression identifies biologically-meaningful microRNAs that distinguish between high-risk and low-risk intraductal papillary mucinous neoplasms of the pancreas. | ||||||||||
| Author: | Permuth-Wey, Jennifer|Chen, Y Ann|Fisher, Kate|McCarthy, Susan|Qu, Xiaotao|Lloyd, Mark C|Kasprzak, Agnieszka|Fournier, Michelle|Williams, Vonetta L|Ghia, Kavita M|Yoder, Sean J|Hall, Laura|Georgeades, Christina|Olaoye, Funmilayo|Husain, Kazim|Springett, G | ||||||||||
| PMID: | 25607660 | ||||||||||
| 16. | |||||||||||
| Journal: | BMC Cancer. 2015 Apr 4;15:223. | ||||||||||
| Title: | Human pancreatic cancer stem cells are sensitive to dual inhibition of IGF-IR and ErbB receptors. | ||||||||||
| Author: | Urtasun, Nerea|Vidal-Pla, Anna|Perez-Torras, Sandra|Mazo, Adela | ||||||||||
| PMID: | 25886138 | ||||||||||
| 17. | |||||||||||
| Journal: | Genome Med. 2016 May 3;8(1):38. | ||||||||||
| Title: | Identification of key regulators of pancreatic cancer progression through multidimensional systems-level analysis. | ||||||||||
| Author: | Rajamani, Deepa|Bhasin, Manoj K | ||||||||||
| PMID: | 27137215 | ||||||||||
| 18. | |||||||||||
| Journal: | Cell Prolif. 2017 Dec;50(6). | ||||||||||
| Title: | Long non-coding RNA CRNDE sponges miR-384 to promote proliferation and metastasis of pancreatic cancer cells through upregulating IRS1. | ||||||||||
| Author: | Wang, Gang|Pan, Jingen|Zhang, Lu|Wei, Yajun|Wang, Cheng | ||||||||||
| PMID: | 28940804 | ||||||||||