Primary Site >> Colorectal Cancer

Gene >> IQGAP1

Journal: Cancer Lett. 2002 Feb 8;176(1):101-9.
Title: Immunohistochemical analysis of IQGAP1 expression in human colorectal carcinomas: its overexpression in carcinomas and association with invasion fronts.
Author: Nabeshima, Kazuki|Shimao, Yoshiya|Inoue, Teruhiko|Koono, Masashi
PMID: 11790459
Journal: Virchows Arch. 2002 Aug;441(2):124-32. Epub 2002 Feb 19.
Title: Complex formation of IQGAP1 with E-cadherin/catenin during cohort migration of carcinoma cells. Its possible association with localized release from cell-cell adhesion.
Author: Shimao, Yoshiya|Nabeshima, Kazuki|Inoue, Teruhiko|Koono, Masashi
PMID: 12189501
Journal: J Biol Chem. 2002 Mar 1;277(9):7453-65. Epub 2001 Dec 4.
Title: IQGAP1-mediated stimulation of transcriptional co-activation by beta-catenin is modulated by calmodulin.
Author: Briggs, Michael W|Li, Zhigang|Sacks, David B
PMID: 11734550
Journal: Biochim Biophys Acta. 2007 Feb;1773(2):120-30.
Title: Characterization of a 60S complex of the adenomatous polyposis coli tumor suppressor protein.
Author: Mahadevaiyer, Sreekala|Xu, Chong|Gumbiner, Barry M
PMID: 17126424
Journal: Med Mol Morphol. 2007 Jun;40(2):68-81. Epub 2007 Jun 18.
Title: Adenomatous polyposis coli (APC) plays multiple roles in the intestinal and colorectal epithelia.
Author: Senda, Takao|Iizuka-Kogo, Akiko|Onouchi, Takanori|Shimomura, Atsushi
PMID: 17572842
Journal: J Cell Sci. 2007 Oct 1;120(Pt 19):3327-35.
Title: Adenomatous polyposis coli (APC): a multi-functional tumor suppressor gene.
Author: Aoki, Koji|Taketo, Makoto M
PMID: 17881494
Journal: Int J Cancer. 2010 Jun 1;126(11):2563-74.
Title: Overexpression of IQGAP1 in advanced colorectal cancer correlates with poor prognosis-critical role in tumor invasion.
Author: Hayashi, Hiroyuki|Nabeshima, Kazuki|Aoki, Mikiko|Hamasaki, Makoto|Enatsu, Sotaro|Yamauchi, Yasushi|Yamashita, Yuichi|Iwasaki, Hiroshi
PMID: 19856315
Journal: Cancer Lett. 2011 Sep 28;308(2):162-71.
Title: Thymosin beta 4 induces colon cancer cell migration and clinical metastasis via enhancing ILK/IQGAP1/Rac1 signal transduction pathway.
Author: Tang, Mei-Chuan|Chan, Li-Chuan|Yeh, Yi-Chen|Chen, Cheng-Yu|Chou, Teh-Ying|Wang, Wei-Shu|Su, Yeu
PMID: 21621326
Journal: J Pers Med. 2014 Jun 5;4(2):282-96.
Title: Differential transcriptome profile of peripheral white cells to identify biomarkers involved in oxaliplatin induced neuropathy.
Author: Morales, Manuel|Avila, Julio|Gonzalez-Fernandez, Rebeca|Boronat, Laia|Soriano, Maria Luisa|Martin-Vasallo, Pablo
PMID: 25563226
Journal: Cell Mol Life Sci. 2014 Jul;71(14):2759-73.
Title: A PAK6-IQGAP1 complex promotes disassembly of cell-cell adhesions.
Author: Fram, Sally|King, Helen|Sacks, David B|Wells, Claire M
PMID: 24352566
Journal: Mol Carcinog. 2015 Oct;54(10):1205-13.
Title: Overexpression of DNAJB6 promotes colorectal cancer cell invasion through an IQGAP1/ERK-dependent signaling pathway.
Author: Zhang, Tong-Tong|Jiang, Yan-Yi|Shang, Li|Shi, Zhi-Zhou|Liang, Jian-Wei|Wang, Zheng|Zhang, Yu|Hao, Jia-Jie|Jia, Xue-Mei|Xu, Xin|Cai, Yan|Zhan, Qi-Min|Wang, Ming-Rong
PMID: 25044025
Journal: Oncogene. 2015 Sep 3;34(36):4692-701.
Title: Aberrant RSPO3-LGR4 signaling in Keap1-deficient lung adenocarcinomas promotes tumor aggressiveness.
Author: Gong, X|Yi, J|Carmon, K S|Crumbley, C A|Xiong, W|Thomas, A|Fan, X|Guo, S|An, Z|Chang, J T|Liu, Q J
PMID: 25531322
Journal: Int J Mol Sci. 2017 Apr 22;18(4). pii: ijms18040891.
Title: Commitment of Scaffold Proteins in the Onco-Biology of Human Colorectal Cancer and Liver Metastases after Oxaliplatin-Based Chemotherapy.
Author: Rotoli, Deborah|Morales, Manuel|Avila, Julio|Maeso, Maria Del Carmen|Garcia, Maria Del Pino|Mobasheri, Ali|Martin-Vasallo, Pablo
PMID: 28441737
Journal: J Biol Chem. 2017 Sep 8;292(36):14989-15001.
Title: LGR5 receptor promotes cell-cell adhesion in stem cells and colon cancer cells via the IQGAP1-Rac1 pathway.
Author: Carmon, Kendra S|Gong, Xing|Yi, Jing|Wu, Ling|Thomas, Anthony|Moore, Catherine M|Masuho, Ikuo|Timson, David J|Martemyanov, Kirill A|Liu, Qingyun J
PMID: 28739799
Journal: Oncol Lett. 2017 Sep;14(3):2621-2628.
Title: Alterations in IQGAP1 expression and localization in colorectal carcinoma and liver metastases following oxaliplatin-based chemotherapy.
Author: Rotoli, Deborah|Morales, Manuel|Maeso, Maria Del Carmen|Garcia, Maria Del Pino|Gutierrez, Ricardo|Valladares, Francisco|Avila, Julio|Diaz-Flores, Lucio|Mobasheri, Ali|Martin-Vasallo, Pablo
PMID: 28928806
Journal: Cancer Lett. 2017 Dec 28;411:90-99.
Title: SUMOylation of IQGAP1 promotes the development of colorectal cancer.
Author: Liang, Ziwei|Yang, Yanfang|He, Yu|Yang, Pengbo|Wang, Xixi|He, Gu|Zhang, Peng|Zhu, Hongxia|Xu, Ningzhi|Zhao, Xia|Liang, Shufang
PMID: 28987385
Journal: PLoS One. 2017 Oct 26;12(10):e0186977.
Title: Reduced expression of IQGAP2 and higher expression of IQGAP3 correlates with poor prognosis in cancers.
Author: Kumar, Dinesh|Hassan, Md Khurshidul|Pattnaik, Niharika|Mohapatra, Nachiketa|Dixit, Manjusha
PMID: 29073199
Journal: Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2018 Feb 1;35(1):81-86.
Title: [A beta-catenin/IQGAP1 regulatory feedback loop and its effects on the proliferation of colon cancer cells].
Author: Xu, Huanji|Xia, Hongwei|Tang, Qiulin|Bi, Feng
PMID: 29745605
Journal: Mol Med Rep. 2018 Sep 27.
Title: miR124 inhibits cell growth through targeting IQGAP1 in colorectal cancer.
Author: Fan, Jianyu|Zhang, Wenjing|Wu, Yanting|Wan, Ping|Guo, Qiang|Zhang, Yu
PMID: 30272357