Primary Site >> Colorectal Cancer

Gene >> IQGAP1

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Ref: IQGAP1-mediated stimulation of transcriptional co-activation by beta-catenin is modulated by calmodulin.
PMID: 11734550
Ref: Immunohistochemical analysis of IQGAP1 expression in human colorectal carcinomas: its overexpression in carcinomas and association with invasion fronts.
PMID: 11790459
Ref: Complex formation of IQGAP1 with E-cadherin/catenin during cohort migration of carcinoma cells. Its possible association with localized release from cell-cell adhesion.
PMID: 12189501
 Ref: Characterization of a 60S complex of the adenomatous polyposis coli tumor suppressor protein.
PMID: 17126424
Ref: Adenomatous polyposis coli (APC) plays multiple roles in the intestinal and colorectal epithelia.
PMID: 17572842
Ref: Adenomatous polyposis coli (APC): a multi-functional tumor suppressor gene.
PMID: 17881494
 Ref: Overexpression of IQGAP1 in advanced colorectal cancer correlates with poor prognosis-critical role in tumor invasion.
PMID: 19856315
 Ref: Thymosin beta 4 induces colon cancer cell migration and clinical metastasis via enhancing ILK/IQGAP1/Rac1 signal transduction pathway.
PMID: 21621326
 Ref: A PAK6-IQGAP1 complex promotes disassembly of cell-cell adhesions.
PMID: 24352566
Ref: Differential transcriptome profile of peripheral white cells to identify biomarkers involved in oxaliplatin induced neuropathy.
PMID: 25563226
 Ref: Overexpression of DNAJB6 promotes colorectal cancer cell invasion through an IQGAP1/ERK-dependent signaling pathway.
PMID: 25044025
Ref: Aberrant RSPO3-LGR4 signaling in Keap1-deficient lung adenocarcinomas promotes tumor aggressiveness.
PMID: 25531322
 Ref: Commitment of Scaffold Proteins in the Onco-Biology of Human Colorectal Cancer and Liver Metastases after Oxaliplatin-Based Chemotherapy.
PMID: 28441737
Ref: LGR5 receptor promotes cell-cell adhesion in stem cells and colon cancer cells via the IQGAP1-Rac1 pathway.
PMID: 28739799
Ref: Alterations in IQGAP1 expression and localization in colorectal carcinoma and liver metastases following oxaliplatin-based chemotherapy.
PMID: 28928806
Ref: SUMOylation of IQGAP1 promotes the development of colorectal cancer.
PMID: 28987385
Ref: Reduced expression of IQGAP2 and higher expression of IQGAP3 correlates with poor prognosis in cancers.
PMID: 29073199
 Ref: [A beta-catenin/IQGAP1 regulatory feedback loop and its effects on the proliferation of colon cancer cells].
PMID: 29745605
Ref: miR124 inhibits cell growth through targeting IQGAP1 in colorectal cancer.
PMID: 30272357