Primary Site >> Colorectal Cancer

Gene >> IP6K2

Journal: Proc Natl Acad Sci U S A. 2010 Dec 7;107(49):20947-51.
Title: p53-mediated apoptosis requires inositol hexakisphosphate kinase-2.
Author: Koldobskiy, Michael A|Chakraborty, Anutosh|Werner, J Kent Jr|Snowman, Adele M|Juluri, Krishna R|Vandiver, M Scott|Kim, Seyun|Heletz, Shira|Snyder, Solomon H
PMID: 21078964
Journal: J Biomol Screen. 2013 Aug;18(7):782-96.
Title: A kinome-wide siRNA screen identifies multiple roles for protein kinases in hypoxic stress adaptation, including roles for IRAK4 and GAK in protection against apoptosis in VHL-/- renal carcinoma cells, despite activation of the NF-kappaB pathway.
Author: Pan, Jing|Zhang, Jing|Hill, Andrew|Lapan, Peter|Berasi, Steve|Bates, Brian|Miller, Christopher|Haney, Steven
PMID: 23591012
Journal: Proc Natl Acad Sci U S A. 2017 Nov 7;114(45):11968-11973.
Title: KO of 5-InsP7 kinase activity transforms the HCT116 colon cancer cell line into a hypermetabolic, growth-inhibited phenotype.
Author: Gu, Chunfang|Nguyen, Hoai-Nghia|Ganini, Douglas|Chen, Zhaowei|Jessen, Henning J|Gu, Zhen|Wang, Huanchen|Shears, Stephen B
PMID: 29078269