Primary Site >> Colorectal Cancer

Gene >> IP6K2

  • 2010
  • 2013
  • 2017
Ref: p53-mediated apoptosis requires inositol hexakisphosphate kinase-2.
PMID: 21078964
 Ref: A kinome-wide siRNA screen identifies multiple roles for protein kinases in hypoxic stress adaptation, including roles for IRAK4 and GAK in protection against apoptosis in VHL-/- renal carcinoma cells, despite activation of the NF-kappaB pathway.
PMID: 23591012
 Ref: KO of 5-InsP7 kinase activity transforms the HCT116 colon cancer cell line into a hypermetabolic, growth-inhibited phenotype.
PMID: 29078269