Primary Site >> Colorectal Cancer
Gene >> ILK
| 1. | |||||||||||
| Journal: | Oncogene. 2001 Jan 4;20(1):133-40. | ||||||||||
| Title: | Inhibition of integrin linked kinase (ILK) suppresses beta-catenin-Lef/Tcf-dependent transcription and expression of the E-cadherin repressor, snail, in APC-/- human colon carcinoma cells. | ||||||||||
| Author: | Tan, C|Costello, P|Sanghera, J|Dominguez, D|Baulida, J|de Herreros, A G|Dedhar, S | ||||||||||
| PMID: | 11244511 | ||||||||||
| 2. | |||||||||||
| Journal: | Pharmacol Ther. 2002 Feb-Mar;93(2-3):233-42. | ||||||||||
| Title: | Integrin-linked kinase, a promising cancer therapeutic target: biochemical and biological properties. | ||||||||||
| Author: | Yoganathan, N|Yee, A|Zhang, Z|Leung, D|Yan, J|Fazli, L|Kojic, D L|Costello, P C|Jabali, M|Dedhar, S|Sanghera, J | ||||||||||
| PMID: | 12191615 | ||||||||||
| 3. | |||||||||||
| Journal: | Br J Cancer. 2003 Jun 2;88(11):1755-62. | ||||||||||
| Title: | Characterisation of integrin-linked kinase signalling in sporadic human colon cancer. | ||||||||||
| Author: | Marotta, A|Parhar, K|Owen, D|Dedhar, S|Salh, B | ||||||||||
| PMID: | 12771992 | ||||||||||
| 4. | |||||||||||
| Journal: | Clin Cancer Res. 2003 Oct 1;9(12):4409-14. | ||||||||||
| Title: | Increased expression of integrin-linked kinase is correlated with melanoma progression and poor patient survival. | ||||||||||
| Author: | Dai, Derek L|Makretsov, Nikita|Campos, Eric I|Huang, Changzheng|Zhou, Youwen|Huntsman, David|Martinka, Madgalena|Li, Gang | ||||||||||
| PMID: | 14555513 | ||||||||||
| 5. | |||||||||||
| Journal: | Br J Cancer. 2003 Dec 15;89(12):2340-1. | ||||||||||
| Title: | Integrin-linked kinase (ILK) expression in human colon cancer. | ||||||||||
| Author: | Bravou, V|Klironomos, G|Papadaki, E|Stefanou, D|Varakis, J | ||||||||||
| PMID: | 14676816 | ||||||||||
| 6. | |||||||||||
| Journal: | Ai Zheng. 2005 Sep;24(9):1064-70. | ||||||||||
| Title: | [Effect of NGX6 on gene expression profile of colon carcinoma cell line HT-29]. | ||||||||||
| Author: | Liu, Fen|Wang, Xiao-Yan|Lian, Ping|Xiao, Zhi-Ming|Shen, Shou-Rong|Ma, Jian|Xiong, Wei | ||||||||||
| PMID: | 16159426 | ||||||||||
| 7. | |||||||||||
| Journal: | Biochem J. 2006 Mar 15;394(Pt 3):647-56. | ||||||||||
| Title: | Plasma-membrane-associated sialidase (NEU3) differentially regulates integrin-mediated cell proliferation through laminin- and fibronectin-derived signalling. | ||||||||||
| Author: | Kato, Kengo|Shiga, Kiyoto|Yamaguchi, Kazunori|Hata, Keiko|Kobayashi, Toshimitsu|Miyazaki, Kaoru|Saijo, Shigeru|Miyagi, Taeko | ||||||||||
| PMID: | 16241905 | ||||||||||
| 8. | |||||||||||
| Journal: | J Pathol. 2006 Jan;208(1):91-9. | ||||||||||
| Title: | ILK over-expression in human colon cancer progression correlates with activation of beta-catenin, down-regulation of E-cadherin and activation of the Akt-FKHR pathway. | ||||||||||
| Author: | Bravou, V|Klironomos, G|Papadaki, E|Taraviras, S|Varakis, J | ||||||||||
| PMID: | 16278819 | ||||||||||
| 9. | |||||||||||
| Journal: | Oncogene. 2007 Apr 26;26(19):2781-90. Epub 2006 Oct 30. | ||||||||||
| Title: | Thymosin beta4 triggers an epithelial-mesenchymal transition in colorectal carcinoma by upregulating integrin-linked kinase. | ||||||||||
| Author: | Huang, H-C|Hu, C-H|Tang, M-C|Wang, W-S|Chen, P-M|Su, Y | ||||||||||
| PMID: | 17072345 | ||||||||||
| 10. | |||||||||||
| Journal: | Gut. 2008 Jul;57(7):931-40. | ||||||||||
| Title: | Integrin-linked kinase regulates cell proliferation and tumour growth in murine colitis-associated carcinogenesis. | ||||||||||
| Author: | Assi, K|Mills, J|Owen, D|Ong, C|St Arnaud, R|Dedhar, S|Salh, B | ||||||||||
| PMID: | 18326560 | ||||||||||
| 11. | |||||||||||
| Journal: | Curr Med Chem. 2008;15(10):978-90. | ||||||||||
| Title: | ANTI-ADHESION evolves to a promising therapeutic concept in oncology. | ||||||||||
| Author: | Schmidmaier, R|Baumann, P | ||||||||||
| PMID: | 18393855 | ||||||||||
| 12. | |||||||||||
| Journal: | FASEB J. 2010 Nov;24(11):4291-301. | ||||||||||
| Title: | Thymosin beta4 targeting impairs tumorigenic activity of colon cancer stem cells. | ||||||||||
| Author: | Ricci-Vitiani, Lucia|Mollinari, Cristiana|di Martino, Simona|Biffoni, Mauro|Pilozzi, Emanuela|Pagliuca, Alfredo|de Stefano, Maria Chiara|Circo, Rita|Merlo, Daniela|De Maria, Ruggero|Garaci, Enrico | ||||||||||
| PMID: | 20566622 | ||||||||||
| 13. | |||||||||||
| Journal: | Planta Med. 2010 Nov;76(16):1827-33. | ||||||||||
| Title: | Andrographolide exhibits anti-invasive activity against colon cancer cells via inhibition of MMP2 activity. | ||||||||||
| Author: | Chao, Hsueh-Ping|Kuo, Cheng-Deng|Chiu, Jen-Hwey|Fu, Shu-Ling | ||||||||||
| PMID: | 20539971 | ||||||||||
| 14. | |||||||||||
| Journal: | Inflamm Bowel Dis. 2010 Jul;16(7):1127-37. | ||||||||||
| Title: | Enhanced expression of proproliferative and antiapoptotic genes in ulcerative colitis-associated neoplasia. | ||||||||||
| Author: | Svec, Jiri|Musilkova, Jana|Bryndova, Jana|Jirasek, Tomas|Mandys, Vaclav|Kment, Milan|Pacha, Jiri | ||||||||||
| PMID: | 20027603 | ||||||||||
| 15. | |||||||||||
| Journal: | Oncogene. 2010 Jan 28;29(4):516-26. | ||||||||||
| Title: | Knockdown of peroxisome proliferator-activated receptor-beta induces less differentiation and enhances cell-fibronectin adhesion of colon cancer cells. | ||||||||||
| Author: | Yang, L|Olsson, B|Pfeifer, D|Jonsson, J-I|Zhou, Z-G|Jiang, X|Fredriksson, B-A|Zhang, H|Sun, X-F | ||||||||||
| PMID: | 19935699 | ||||||||||
| 16. | |||||||||||
| Journal: | Int J Exp Pathol. 2010 Feb;91(1):44-53. | ||||||||||
| Title: | Expression profiles of proliferative and antiapoptotic genes in sporadic and colitis-related mouse colon cancer models. | ||||||||||
| Author: | Svec, Jiri|Ergang, Peter|Mandys, Vaclav|Kment, Milan|Pacha, Jiri | ||||||||||
| PMID: | 20096072 | ||||||||||
| 17. | |||||||||||
| Journal: | Oncogene. 2011 Jun 30;30(26):2997-3002. | ||||||||||
| Title: | Cten signals through integrin-linked kinase (ILK) and may promote metastasis in colorectal cancer. | ||||||||||
| Author: | Albasri, A|Al-Ghamdi, S|Fadhil, W|Aleskandarany, M|Liao, Y-C|Jackson, D|Lobo, D N|Lo, S H|Kumari, R|Durrant, L|Watson, S|Kindle, K B|Ilyas, M | ||||||||||
| PMID: | 21339732 | ||||||||||
| 18. | |||||||||||
| Journal: | Cancer Lett. 2011 Sep 28;308(2):162-71. | ||||||||||
| Title: | Thymosin beta 4 induces colon cancer cell migration and clinical metastasis via enhancing ILK/IQGAP1/Rac1 signal transduction pathway. | ||||||||||
| Author: | Tang, Mei-Chuan|Chan, Li-Chuan|Yeh, Yi-Chen|Chen, Cheng-Yu|Chou, Teh-Ying|Wang, Wei-Shu|Su, Yeu | ||||||||||
| PMID: | 21621326 | ||||||||||
| 19. | |||||||||||
| Journal: | Oncogene. 2012 Mar 29;31(13):1623-35. | ||||||||||
| Title: | MicroRNA-mediated upregulation of integrin-linked kinase promotes Src-induced tumor progression. | ||||||||||
| Author: | Oneyama, C|Morii, E|Okuzaki, D|Takahashi, Y|Ikeda, J|Wakabayashi, N|Akamatsu, H|Tsujimoto, M|Nishida, T|Aozasa, K|Okada, M | ||||||||||
| PMID: | 21860426 | ||||||||||
| 20. | |||||||||||
| Journal: | Mol Biosyst. 2012 Apr;8(4):1230-42. | ||||||||||
| Title: | Analysis of cell adhesion during early stages of colon cancer based on an extended multi-valued logic approach. | ||||||||||
| Author: | Guebel, Daniel V|Schmitz, Ulf|Wolkenhauer, Olaf|Vera, Julio | ||||||||||
| PMID: | 22298312 | ||||||||||
| 21. | |||||||||||
| Journal: | J Mol Histol. 2013 Apr;44(2):183-9. | ||||||||||
| Title: | Overexpression of integrin-linked kinase (ILK) is associated with tumor progression and an unfavorable prognosis in patients with colorectal cancer. | ||||||||||
| Author: | Li, Rui|Liu, Baolin|Yin, Hongzhuan|Sun, Wei|Yin, Jianqiao|Su, Qi | ||||||||||
| PMID: | 23108908 | ||||||||||
| 22. | |||||||||||
| Journal: | Nat Commun. 2013;4:2976. | ||||||||||
| Title: | Inactivation of the Hippo tumour suppressor pathway by integrin-linked kinase. | ||||||||||
| Author: | Serrano, Isabel|McDonald, Paul C|Lock, Frances|Muller, William J|Dedhar, Shoukat | ||||||||||
| PMID: | 24356468 | ||||||||||
| 23. | |||||||||||
| Journal: | J Recept Signal Transduct Res. 2014 Feb;34(1):64-72. | ||||||||||
| Title: | The integrin-linked kinase gene up-regulated by hypoxia plays its pro-survival role in colorectal cancer cells. | ||||||||||
| Author: | Xiao, Lei|Yue, Xiaolong|Ming, Xiaodong|Xu, Lishan|Ding, Mingfeng|Xu, Jun|Liu, Qian | ||||||||||
| PMID: | 24299190 | ||||||||||
| 24. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2014 Sep 26;452(3):858-64. | ||||||||||
| Title: | Thymosin beta4 induces invasion and migration of human colorectal cancer cells through the ILK/AKT/beta-catenin signaling pathway. | ||||||||||
| Author: | Piao, Zhengri|Hong, Chang-Soo|Jung, Mi-Ran|Choi, Chan|Park, Young-Kyu | ||||||||||
| PMID: | 25218472 | ||||||||||
| 25. | |||||||||||
| Journal: | Acta Histochem. 2014 Apr;116(3):527-33. | ||||||||||
| Title: | Overexpression of integrin-linked kinase (ILK) promotes migration and invasion of colorectal cancer cells by inducing epithelial-mesenchymal transition via NF-kappaB signaling. | ||||||||||
| Author: | Yan, Zhaopeng|Yin, Hongzhuan|Wang, Rui|Wu, Di|Sun, Wei|Liu, Baolin|Su, Qi | ||||||||||
| PMID: | 24360977 | ||||||||||
| 26. | |||||||||||
| Journal: | Cancer Invest. 2015;33(8):387-97. | ||||||||||
| Title: | Focal Adhesion Proteins alpha- and beta-Parvin are Overexpressed in Human Colorectal Cancer and Correlate with Tumor Progression. | ||||||||||
| Author: | Bravou, Vasiliki|Antonacopoulou, Anna|Papanikolaou, Sofia|Nikou, Sofia|Lilis, Ioannis|Giannopoulou, Efstathia|Kalofonos, Haralabos P | ||||||||||
| PMID: | 26115385 | ||||||||||
| 27. | |||||||||||
| Journal: | Oncogene. 2016 Feb 4;35(5):549-57. | ||||||||||
| Title: | Induction of the intestinal stem cell signature gene SMOC-2 is required for L1-mediated colon cancer progression. | ||||||||||
| Author: | Shvab, A|Haase, G|Ben-Shmuel, A|Gavert, N|Brabletz, T|Dedhar, S|Ben-Ze'ev, A | ||||||||||
| PMID: | 25915847 | ||||||||||
| 28. | |||||||||||
| Journal: | World J Gastroenterol. 2016 Apr 21;22(15):3969-77. | ||||||||||
| Title: | Integrin-linked kinase overexpression promotes epithelial-mesenchymal transition via nuclear factor-kappaB signaling in colorectal cancer cells. | ||||||||||
| Author: | Shen, Hong|Ma, Jun-Li|Zhang, Yan|Deng, Gan-Lu|Qu, Yan-Ling|Wu, Xiao-Ling|He, Jing-Xuan|Zhang, Sai|Zeng, Shan | ||||||||||
| PMID: | 27099440 | ||||||||||
| 29. | |||||||||||
| Journal: | Biochim Biophys Acta Mol Cell Res. 2017 Dec;1864(12):2283-2296. | ||||||||||
| Title: | The ILK-MMP9-MRTF axis is crucial for EndMT differentiation of endothelial cells in a tumor microenvironment. | ||||||||||
| Author: | Ciszewski, Wojciech M|Sobierajska, Katarzyna|Wawro, Marta E|Klopocka, Wanda|Chefczynska, Natasza|Muzyczuk, Angelika|Siekacz, Kamil|Wujkowska, Agata|Niewiarowska, Jolanta | ||||||||||
| PMID: | 28893556 | ||||||||||
| 30. | |||||||||||
| Journal: | J Gastrointest Cancer. 2017 Nov 7. pii: 10.1007/s12029-017-0024-9. | ||||||||||
| Title: | A Deregulated PI3K-AKT Signaling Pathway in Patients with Colorectal Cancer. | ||||||||||
| Author: | Zhang, Tao|Ma, Yuanping|Fang, Jiansong|Liu, Chang|Chen, Liangrong | ||||||||||
| PMID: | 29110225 | ||||||||||
| 31. | |||||||||||
| Journal: | Cancer Genomics Proteomics. 2018 Mar-Apr;15(2):127-141. | ||||||||||
| Title: | ILK Expression in Colorectal Cancer Is Associated with EMT, Cancer Stem Cell Markers and Chemoresistance. | ||||||||||
| Author: | Tsoumas, Dimitrios|Nikou, Sofia|Giannopoulou, Efstathia|Champeris Tsaniras, Spyridon|Sirinian, Chaido|Maroulis, Ioannis|Taraviras, Stavros|Zolota, Vassiliki|Kalofonos, Haralabos P|Bravou, Vasiliki | ||||||||||
| PMID: | 29496692 | ||||||||||