Primary Site >> Colorectal Cancer
Gene >> ILK
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Ref: Inhibition of integrin linked kinase (ILK) suppresses beta-catenin-Lef/Tcf-dependent transcription and expression of the E-cadherin repressor, snail, in APC-/- human colon carcinoma cells. PMID: 11244511 |
Ref: Integrin-linked kinase, a promising cancer therapeutic target: biochemical and biological properties. PMID: 12191615 |
Ref: Characterisation of integrin-linked kinase signalling in sporadic human colon cancer. PMID: 12771992 Ref: Increased expression of integrin-linked kinase is correlated with melanoma progression and poor patient survival. PMID: 14555513 Ref: Integrin-linked kinase (ILK) expression in human colon cancer. PMID: 14676816 |
Ref: [Effect of NGX6 on gene expression profile of colon carcinoma cell line HT-29]. PMID: 16159426 |
Ref: Plasma-membrane-associated sialidase (NEU3) differentially regulates integrin-mediated cell proliferation through laminin- and fibronectin-derived signalling. PMID: 16241905 Ref: ILK over-expression in human colon cancer progression correlates with activation of beta-catenin, down-regulation of E-cadherin and activation of the Akt-FKHR pathway. PMID: 16278819 |
Ref: Thymosin beta4 triggers an epithelial-mesenchymal transition in colorectal carcinoma by upregulating integrin-linked kinase. PMID: 17072345 |
Ref: Integrin-linked kinase regulates cell proliferation and tumour growth in murine colitis-associated carcinogenesis. PMID: 18326560 Ref: ANTI-ADHESION evolves to a promising therapeutic concept in oncology. PMID: 18393855 |
Ref: Knockdown of peroxisome proliferator-activated receptor-beta induces less differentiation and enhances cell-fibronectin adhesion of colon cancer cells. PMID: 19935699 Ref: Enhanced expression of proproliferative and antiapoptotic genes in ulcerative colitis-associated neoplasia. PMID: 20027603 Ref: Expression profiles of proliferative and antiapoptotic genes in sporadic and colitis-related mouse colon cancer models. PMID: 20096072 Ref: Andrographolide exhibits anti-invasive activity against colon cancer cells via inhibition of MMP2 activity. PMID: 20539971 Ref: Thymosin beta4 targeting impairs tumorigenic activity of colon cancer stem cells. PMID: 20566622 |
Ref: Cten signals through integrin-linked kinase (ILK) and may promote metastasis in colorectal cancer. PMID: 21339732 Ref: Thymosin beta 4 induces colon cancer cell migration and clinical metastasis via enhancing ILK/IQGAP1/Rac1 signal transduction pathway. PMID: 21621326 |
Ref: MicroRNA-mediated upregulation of integrin-linked kinase promotes Src-induced tumor progression. PMID: 21860426 Ref: Analysis of cell adhesion during early stages of colon cancer based on an extended multi-valued logic approach. PMID: 22298312 |
Ref: Overexpression of integrin-linked kinase (ILK) is associated with tumor progression and an unfavorable prognosis in patients with colorectal cancer. PMID: 23108908 Ref: Inactivation of the Hippo tumour suppressor pathway by integrin-linked kinase. PMID: 24356468 |
Ref: The integrin-linked kinase gene up-regulated by hypoxia plays its pro-survival role in colorectal cancer cells. PMID: 24299190 Ref: Overexpression of integrin-linked kinase (ILK) promotes migration and invasion of colorectal cancer cells by inducing epithelial-mesenchymal transition via NF-kappaB signaling. PMID: 24360977 Ref: Thymosin beta4 induces invasion and migration of human colorectal cancer cells through the ILK/AKT/beta-catenin signaling pathway. PMID: 25218472 |
Ref: Focal Adhesion Proteins alpha- and beta-Parvin are Overexpressed in Human Colorectal Cancer and Correlate with Tumor Progression. PMID: 26115385 |
Ref: Induction of the intestinal stem cell signature gene SMOC-2 is required for L1-mediated colon cancer progression. PMID: 25915847 Ref: Integrin-linked kinase overexpression promotes epithelial-mesenchymal transition via nuclear factor-kappaB signaling in colorectal cancer cells. PMID: 27099440 |
Ref: The ILK-MMP9-MRTF axis is crucial for EndMT differentiation of endothelial cells in a tumor microenvironment. PMID: 28893556 Ref: A Deregulated PI3K-AKT Signaling Pathway in Patients with Colorectal Cancer. PMID: 29110225 |
Ref: ILK Expression in Colorectal Cancer Is Associated with EMT, Cancer Stem Cell Markers and Chemoresistance. PMID: 29496692 |