Primary Site >> Colorectal Cancer

Gene >> IL6ST

Journal: Cancer Lett. 2000 Apr 3;151(1):31-8.
Title: Interleukin-6 stimulates clonogenic growth of primary and metastatic human colon carcinoma cells.
Author: Schneider, M R|Hoeflich, A|Fischer, J R|Wolf, E|Sordat, B|Lahm, H
PMID: 10766420
Journal: J Gastroenterol Hepatol. 2001 Sep;16(9):991-1000.
Title: Expression of interleukin-6, leukemia inhibitory factor and their receptors by colonic epithelium and pericryptal fibroblasts.
Author: Rockman, S P|Demmler, K|Roczo, N|Cosgriff, A|Phillips, W A|Thomas, R J|Whitehead, R H
PMID: 11595063
Journal: Biochem Biophys Res Commun. 2005 Jan 28;326(4):724-8.
Title: No inhibition of IL-27 signaling by soluble gp130.
Author: Scheller, Jurgen|Schuster, Bjorn|Holscher, Christoph|Yoshimoto, Takayuki|Rose-John, Stefan
PMID: 15607729
Journal: Clin Rev Allergy Immunol. 2005 Jun;28(3):187-96.
Title: Involvement of IL-6 in the pathogenesis of inflammatory bowel disease and colon cancer.
Author: Atreya, Raja|Neurath, Markus F
PMID: 16129903
Journal: Scand J Immunol. 2006 May;63(5):321-9.
Title: Interleukin-6 trans-signalling in chronic inflammation and cancer.
Author: Scheller, J|Ohnesorge, N|Rose-John, S
PMID: 16640655
Journal: J Leukoc Biol. 2006 Aug;80(2):227-36.
Title: Interleukin-6 biology is coordinated by membrane-bound and soluble receptors: role in inflammation and cancer.
Author: Rose-John, Stefan|Scheller, Jurgen|Elson, Greg|Jones, Simon A
PMID: 16707558
Journal: Hum Immunol. 2009 Mar;70(3):151-8.
Title: Interleukin-6 (IL-6) released by macrophages induces IL-6 secretion in the human colon cancer HT-29 cell line.
Author: Li, Ying-Ying|Hsieh, Ling-Ling|Tang, Rei-Ping|Liao, Shuen-Keui|Yeh, Kun-Yun
PMID: 19272324
Journal: Curr Pharm Des. 2009;15(18):2095-103.
Title: Interleukin-6 trans-signaling and colonic cancer associated with inflammatory bowel disease.
Author: Rose-John, Stefan|Mitsuyama, Keiichi|Matsumoto, Satoshi|Thaiss, Wolfgang M|Scheller, Jurgen
PMID: 19519447
Journal: Br J Cancer. 2010 Sep 7;103(6):787-95.
Title: Loss of tumoral expression of soluble IL-6 receptor is associated with disease progression in colorectal cancer.
Author: Okugawa, Y|Miki, C|Toiyama, Y|Yasuda, H|Yokoe, T|Saigusa, S|Hiro, J|Tanaka, K|Inoue, Y|Kusunoki, M
PMID: 20823887
Journal: Eur J Cell Biol. 2011 Jun-Jul;90(6-7):484-94.
Title: The soluble Interleukin 6 receptor: generation and role in inflammation and cancer.
Author: Chalaris, Athena|Garbers, Christoph|Rabe, Bjorn|Rose-John, Stefan|Scheller, Jurgen
PMID: 21145125
Journal: J Biosci. 2012 Jun;37(2):243-57.
Title: STAT3 mutations correlated with hyper-IgE syndrome lead to blockage of IL-6/STAT3 signalling pathway.
Author: He, Jianxin|Shi, Jie|Xu, Ximing|Zhang, Wenhua|Wang, Yuxin|Chen, Xing|Du, Yuping|Zhu, Ning|Zhang, Jing|Wang, Qin|Yang, Jinbo
PMID: 22581330
Journal: Dig Dis. 2012;30(5):492-9.
Title: Interleukin-6 trans-signaling and colonic cancer associated with inflammatory bowel disease.
Author: Chalaris, Athena|Schmidt-Arras, Dirk|Yamamoto, Kosuke|Rose-John, Stefan
PMID: 23108305
Journal: J Clin Invest. 2013 Feb;123(2):767-81.
Title: mTORC1 inhibition restricts inflammation-associated gastrointestinal tumorigenesis in mice.
Author: Thiem, Stefan|Pierce, Thomas P|Palmieri, Michelle|Putoczki, Tracy L|Buchert, Michael|Preaudet, Adele|Farid, Ryan O|Love, Chris|Catimel, Bruno|Lei, Zhengdeng|Rozen, Steve|Gopalakrishnan, Veena|Schaper, Fred|Hallek, Michael|Boussioutas, Alex|Tan, Patrick|Ja
PMID: 23321674
Journal: Bio Protoc. 2014 May 5;4(9).
Title: Immunostaining Protocol: P-Stat3 (Xenograft and Mice).
Author: Calon, Alexandre|Espinet, Elisa|Palomo-Ponce, Sergio|Tauriello, Daniele V F|Iglesias, Mar|Cespedes, Maria Virtudes|Sevillano, Marta|Nadal, Cristina|Jung, Peter|Zhang, Xiang H-F|Byrom, Daniel|Riera, Antoni|Rossell, David|Mangues, Ramon|Massague, Joan|Sanch
PMID: 29104885
Journal: Oncotarget. 2016 Feb 16;7(7):7667-82.
Title: Sonic hedgehog inhibitors prevent colitis-associated cancer via orchestrated mechanisms of IL-6/gp130 inhibition, 15-PGDH induction, Bcl-2 abrogation, and tumorsphere inhibition.
Author: Kangwan, Napapan|Kim, Yoon-Jae|Han, Young Min|Jeong, Migyeong|Park, Jong-Min|Go, Eun-Jin|Hahm, Ki-Baik
PMID: 26716648
Journal: Cytokine. 2016 Mar;79:82-9.
Title: Colorectal cancer cell-derived interleukin-6 enhances the phagocytic capacity and migration of THP-1 cells.
Author: Yeh, Kun-Yun|Wu, Tsung-Han|Wu, Tai-Ling
PMID: 26775116
Journal: Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):1643-1648.
Title: YAP-IL-6ST autoregulatory loop activated on APC loss controls colonic tumorigenesis.
Author: Taniguchi, Koji|Moroishi, Toshiro|de Jong, Petrus R|Krawczyk, Michal|Grebbin, Britta Moyo|Luo, Huiyan|Xu, Rui-Hua|Golob-Schwarzl, Nicole|Schweiger, Caroline|Wang, Kepeng|Di Caro, Giuseppe|Feng, Ying|Fearon, Eric R|Raz, Eyal|Kenner, Lukas|Farin, Henner F|G
PMID: 28130546
Journal: Gut. 2018 Mar;67(3):473-484.
Title: Protein and glycomic plasma markers for early detection of adenoma and colon cancer.
Author: Rho, Jung-Hyun|Ladd, Jon J|Li, Christopher I|Potter, John D|Zhang, Yuzheng|Shelley, David|Shibata, David|Coppola, Domenico|Yamada, Hiroyuki|Toyoda, Hidenori|Tada, Toshifumi|Kumada, Takashi|Brenner, Dean E|Hanash, Samir M|Lampe, Paul D
PMID: 27821646
Journal: Mol Cell Biochem. 2018 Sep;446(1-2):137-148.
Title: P16 promotes the growth and mobility potential of breast cancer both in vitro and in vivo: the key role of the activation of IL-6/JAK2/STAT3 signaling.
Author: Wang, Le|Zhan, Xiangwen|Shen, Xiaomeng|Li, Mingzhe|Yang, Jianming|Yu, Wenhua|Chen, Hao|Jin, Bo|Mao, Zebin
PMID: 29388151
Journal: Mol Med Rep. 2018 Aug;18(2):1909-1916.
Title: MicroRNA expression profiles identify biomarkers for predicting the response to chemoradiotherapy in rectal cancer.
Author: Du, Binbin|Wang, Xiaoying|Wu, Dewang|Wang, Tao|Yang, Xiongfei|Wang, Jiankai|Shi, Xinlong|Chen, Lingjuan|Zhang, Weisheng
PMID: 29956755