Primary Site >> Colorectal Cancer

Gene >> IL6ST

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Ref: Interleukin-6 stimulates clonogenic growth of primary and metastatic human colon carcinoma cells.
PMID: 10766420
Ref: Expression of interleukin-6, leukemia inhibitory factor and their receptors by colonic epithelium and pericryptal fibroblasts.
PMID: 11595063
Ref: No inhibition of IL-27 signaling by soluble gp130.
PMID: 15607729
Ref: Involvement of IL-6 in the pathogenesis of inflammatory bowel disease and colon cancer.
PMID: 16129903
Ref: Interleukin-6 trans-signalling in chronic inflammation and cancer.
PMID: 16640655
Ref: Interleukin-6 biology is coordinated by membrane-bound and soluble receptors: role in inflammation and cancer.
PMID: 16707558
Ref: Interleukin-6 (IL-6) released by macrophages induces IL-6 secretion in the human colon cancer HT-29 cell line.
PMID: 19272324
Ref: Interleukin-6 trans-signaling and colonic cancer associated with inflammatory bowel disease.
PMID: 19519447
Ref: Loss of tumoral expression of soluble IL-6 receptor is associated with disease progression in colorectal cancer.
PMID: 20823887
Ref: The soluble Interleukin 6 receptor: generation and role in inflammation and cancer.
PMID: 21145125
Ref: STAT3 mutations correlated with hyper-IgE syndrome lead to blockage of IL-6/STAT3 signalling pathway.
PMID: 22581330
Ref: Interleukin-6 trans-signaling and colonic cancer associated with inflammatory bowel disease.
PMID: 23108305
Ref: mTORC1 inhibition restricts inflammation-associated gastrointestinal tumorigenesis in mice.
PMID: 23321674
Ref: Immunostaining Protocol: P-Stat3 (Xenograft and Mice).
PMID: 29104885
Ref: Sonic hedgehog inhibitors prevent colitis-associated cancer via orchestrated mechanisms of IL-6/gp130 inhibition, 15-PGDH induction, Bcl-2 abrogation, and tumorsphere inhibition.
PMID: 26716648
Ref: Colorectal cancer cell-derived interleukin-6 enhances the phagocytic capacity and migration of THP-1 cells.
PMID: 26775116
Ref: YAP-IL-6ST autoregulatory loop activated on APC loss controls colonic tumorigenesis.
PMID: 28130546
Ref: Protein and glycomic plasma markers for early detection of adenoma and colon cancer.
PMID: 27821646
Ref: P16 promotes the growth and mobility potential of breast cancer both in vitro and in vivo: the key role of the activation of IL-6/JAK2/STAT3 signaling.
PMID: 29388151
Ref: MicroRNA expression profiles identify biomarkers for predicting the response to chemoradiotherapy in rectal cancer.
PMID: 29956755