Primary Site >> Colorectal Cancer

Gene >> IL6R

Journal: J Leukoc Biol. 2006 Aug;80(2):227-36.
Title: Interleukin-6 biology is coordinated by membrane-bound and soluble receptors: role in inflammation and cancer.
Author: Rose-John, Stefan|Scheller, Jurgen|Elson, Greg|Jones, Simon A
PMID: 16707558
Journal: Exp Mol Med. 2009 Oct 31;41(10):717-27.
Title: Triptolide downregulates Rac1 and the JAK/STAT3 pathway and inhibits colitis-related colon cancer progression.
Author: Wang, Zhipeng|Jin, Haifeng|Xu, Ruodan|Mei, Qibing|Fan, Daiming
PMID: 19561401
Journal: Int J Cancer. 2013 Feb 15;132(4):905-15.
Title: Interleukin genes and associations with colon and rectal cancer risk and overall survival.
Author: Bondurant, Kristina L|Lundgreen, Abbie|Herrick, Jennifer S|Kadlubar, Susan|Wolff, Roger K|Slattery, Martha L
PMID: 22674296
Journal: J Clin Invest. 2014 Apr;124(4):1853-67.
Title: IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis.
Author: Rokavec, Matjaz|Oner, Meryem Gulfem|Li, Huihui|Jackstadt, Rene|Jiang, Longchang|Lodygin, Dmitri|Kaller, Markus|Horst, David|Ziegler, Paul K|Schwitalla, Sarah|Slotta-Huspenina, Julia|Bader, Franz G|Greten, Florian R|Hermeking, Heiko
PMID: 24642471
Journal: Int J Immunogenet. 2014 Aug;41(4):289-97.
Title: Polymorphisms of inflammation-related genes and colorectal cancer risk: a population-based case-control study in China.
Author: Yu, Y|Zheng, S|Zhang, S|Jin, W|Liu, H|Jin, M|Chen, Z|Ding, Z|Wang, L|Chen, K
PMID: 24762198
Journal: Dis Markers. 2014;2014:634123.
Title: Gene expression profiling of colorectal tumors and normal mucosa by microarrays meta-analysis using prediction analysis of microarray, artificial neural network, classification, and regression trees.
Author: Chu, Chi-Ming|Yao, Chung-Tay|Chang, Yu-Tien|Chou, Hsiu-Ling|Chou, Yu-Ching|Chen, Kang-Hua|Terng, Harn-Jing|Huang, Chi-Shuan|Lee, Chia-Cheng|Su, Sui-Lun|Liu, Yao-Chi|Lin, Fu-Gong|Wetter, Thomas|Chang, Chi-Wen
PMID: 24959000
Journal: Gastroenterology. 2015 Mar;148(3):579-89.
Title: Interleukin 6 alters localization of hMSH3, leading to DNA mismatch repair defects in colorectal cancer cells.
Author: Tseng-Rogenski, Stephanie S|Hamaya, Yasushi|Choi, Daniel Y|Carethers, John M
PMID: 25461668
Journal: Oncotarget. 2015 Jun 10;6(16):14026-32.
Title: Soluble IL6R represents a miR-34a target: potential implications for the recently identified IL-6R/STAT3/miR-34a feed-back loop.
Author: Li, Huihui|Rokavec, Matjaz|Hermeking, Heiko
PMID: 26091352
Journal: Cell Rep. 2016 Mar 22;14(11):2562-75.
Title: The Innate Immune Receptor NLRX1 Functions as a Tumor Suppressor by Reducing Colon Tumorigenesis and Key Tumor-Promoting Signals.
Author: Koblansky, A Alicia|Truax, Agnieszka D|Liu, Rongrong|Montgomery, Stephanie A|Ding, Shengli|Wilson, Justin E|Brickey, W June|Muhlbauer, Marcus|McFadden, Rita-Marie T|Hu, Peizhen|Li, Zengshan|Jobin, Christian|Lund, Pauline Kay|Ting, Jenny P-Y
PMID: 26971998
Journal: Onco Targets Ther. 2016 Jun 1;9:3313-25.
Title: Filtered selection coupled with support vector machines generate a functionally relevant prediction model for colorectal cancer.
Author: Gabere, Musa Nur|Hussein, Mohamed Aly|Aziz, Mohammad Azhar
PMID: 27330311
Journal: Clin Cancer Res. 2017 Dec 1;23(23):7375-7387.
Title: The Immune-microenvironment Confers Chemoresistance of Colorectal Cancer through Macrophage-Derived IL6.
Author: Yin, Yuan|Yao, Surui|Hu, Yaling|Feng, Yuyang|Li, Min|Bian, Zehua|Zhang, Jiwei|Qin, Yan|Qi, Xiaowei|Zhou, Leyuan|Fei, Bojian|Zou, Jian|Hua, Dong|Huang, Zhaohui
PMID: 28928161
Journal: Mol Carcinog. 2018 Feb;57(2):243-261.
Title: The PI3K/AKT signaling pathway: Associations of miRNAs with dysregulated gene expression in colorectal cancer.
Author: Slattery, Martha L|Mullany, Lila E|Sakoda, Lori C|Wolff, Roger K|Stevens, John R|Samowitz, Wade S|Herrick, Jennifer S
PMID: 29068474
Journal: Microvasc Res. 2018 May 17;120:21-28.
Title: Human cancer cells suppress behaviors of endothelial progenitor cells through miR-21 targeting IL6R.
Author: Wang, Wenbin|Yuan, Xiao|Xu, Aman|Zhu, Xingyang|Zhan, Yanqing|Wang, Shuanhu|Liu, Mulin
PMID: 29777792
Journal: Gastroenterology. 2018 Aug 9. pii: S0016-5085(18)34868-6.
Title: Combined Inactivation of TP53 and MIR34A Promotes Colorectal Cancer Development and Progression in Mice via Increasing Levels of IL6R and PAI1.
Author: Oner, Meryem Gulfem|Rokavec, Matjaz|Kaller, Markus|Bouznad, Nassim|Horst, David|Kirchner, Thomas|Hermeking, Heiko
PMID: 30099074