Primary Site >> Colorectal Cancer
Gene >> IL6R
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Ref: Interleukin-6 biology is coordinated by membrane-bound and soluble receptors: role in inflammation and cancer. PMID: 16707558 |
Ref: Triptolide downregulates Rac1 and the JAK/STAT3 pathway and inhibits colitis-related colon cancer progression. PMID: 19561401 |
Ref: Interleukin genes and associations with colon and rectal cancer risk and overall survival. PMID: 22674296 |
Ref: IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis. PMID: 24642471 Ref: Polymorphisms of inflammation-related genes and colorectal cancer risk: a population-based case-control study in China. PMID: 24762198 Ref: Gene expression profiling of colorectal tumors and normal mucosa by microarrays meta-analysis using prediction analysis of microarray, artificial neural network, classification, and regression trees. PMID: 24959000 |
Ref: Interleukin 6 alters localization of hMSH3, leading to DNA mismatch repair defects in colorectal cancer cells. PMID: 25461668 Ref: Soluble IL6R represents a miR-34a target: potential implications for the recently identified IL-6R/STAT3/miR-34a feed-back loop. PMID: 26091352 |
Ref: The Innate Immune Receptor NLRX1 Functions as a Tumor Suppressor by Reducing Colon Tumorigenesis and Key Tumor-Promoting Signals. PMID: 26971998 Ref: Filtered selection coupled with support vector machines generate a functionally relevant prediction model for colorectal cancer. PMID: 27330311 |
Ref: The Immune-microenvironment Confers Chemoresistance of Colorectal Cancer through Macrophage-Derived IL6. PMID: 28928161 |
Ref: The PI3K/AKT signaling pathway: Associations of miRNAs with dysregulated gene expression in colorectal cancer. PMID: 29068474 Ref: Human cancer cells suppress behaviors of endothelial progenitor cells through miR-21 targeting IL6R. PMID: 29777792 Ref: Combined Inactivation of TP53 and MIR34A Promotes Colorectal Cancer Development and Progression in Mice via Increasing Levels of IL6R and PAI1. PMID: 30099074 |