Primary Site >> Colorectal Cancer

Gene >> IL2RA

Journal: Clin Immunol Immunopathol. 1989 Jan;50(1 Pt 1):72-81.
Title: Characterization of activated lymphocytes in colon cancer.
Author: Ebert, E C|Brolin, R E|Roberts, A I
PMID: 2783402
Journal: J Formos Med Assoc. 1990 Mar;89(3):205-13.
Title: Proliferation, interleukin-2 production and receptor expression in peripheral blood mononuclear cells from colorectal cancer patients.
Author: Chang, K J|Wang, S M|Lee, C S|Hsieh, K H|Chen, K M
PMID: 1974593
Journal: Cancer Immunol Immunother. 1990;31(4):231-5.
Title: Granulocyte-monocyte colony-stimulating-factor augments the interleukin-2-induced cytotoxic activity of human lymphocytes in the absence and presence of mouse or chimeric monoclonal antibodies (mAb 17-1A).
Author: Masucci, G|Ragnhammar, P|Wersall, P|Mellstedt, H
PMID: 2199042
Journal: J Immunother (1991). 1991 Oct;10(5):297-306.
Title: Immunological effects of levamisole in vitro.
Author: Schiller, J H|Lindstrom, M|Witt, P L|Hank, J A|Mahvi, D|Wagner, R J|Sondel, P|Borden, E C
PMID: 1790137
Journal: Eur J Cancer. 1991;27(2):149-54.
Title: Factors influencing the establishment of tumour-infiltrating lymphocyte cultures from human breast carcinoma and colon carcinoma tissue.
Author: Crannage, K E|Rogers, K|Jacob, G|Stoddard, C J|Thomas, W E|Potter, C W|Rees, R C
PMID: 1827279
Journal: Cancer Res. 1991 Dec 1;51(23 Pt 1):6312-6.
Title: Biological monitoring of low-dose interleukin 2 in humans: soluble interleukin 2 receptors, cytokines, and cell surface phenotypes.
Author: Hanninen, E L|Korfer, A|Hadam, M|Schneekloth, C|Dallmann, I|Menzel, T|Kirchner, H|Poliwoda, H|Atzpodien, J
PMID: 1933892
Journal: Cancer Res. 1991 Mar 15;51(6):1651-8.
Title: Biological and clinical effects of intravenous tumor necrosis factor-alpha administered three times weekly.
Author: Schiller, J H|Storer, B E|Witt, P L|Alberti, D|Tombes, M B|Arzoomanian, R|Proctor, R A|McCarthy, D|Brown, R R|Voss, S D
PMID: 1998956
Journal: Biotherapy. 1992;5(4):241-50.
Title: Establishment of cytotoxic CD4+ T cell clones from cancer patients treated by local immunotherapy.
Author: Nagaoka, H|Monden, T|Sakita, I|Katsumoto, Y|Wakasugi, T|Kawasaki, Y|Tomita, N|Takeda, T|Yagyu, T|Morimoto, H
PMID: 1363274
Journal: Exp Toxicol Pathol. 1992 Aug;44(4):214-6.
Title: Mononuclear cells in normal colon and colonic carcinoma express the same T cell activation markers.
Author: Norazmi, M N|Hohmann, A W|Skinner, J M|Bradley, J
PMID: 1392524
Journal: Cancer Res. 1992 Oct 15;52(20):5765-9.
Title: Perioperative immunotherapy with recombinant interleukin 2 in patients undergoing surgery for colorectal cancer.
Author: Nichols, P H|Ramsden, C W|Ward, U|Sedman, P C|Primrose, J N
PMID: 1394200
Journal: J Pathol. 1992 Jul;167(3):313-9.
Title: Immunopathological changes in the skin following recombinant interleukin-2 treatment.
Author: Blessing, K|Park, K G|Heys, S D|King, G|Eremin, O
PMID: 1517903
Journal: Clin Exp Immunol. 1992 Apr;88(1):132-7.
Title: IL-2 production by intestinal lamina propria cells in normal inflamed and cancer-bearing colons.
Author: Pullman, W E|Doe, W F
PMID: 1563100
Journal: Acta Haematol. 1993;89(1):13-21.
Title: Low-dose interleukin-2 in combination with interferon-alpha effectively modulates biological response in vivo.
Author: Schneekloth, C|Korfer, A|Hadam, M|Lopez Hanninen, E|Menzel, T|Schomburg, A|Dallmann, I|Kirchner, H|Poliwoda, H|Atzpodien, J
PMID: 7683166
Journal: Eur J Surg. 1993 Jan;159(1):43-7.
Title: Effects of a preoperative course of interleukin-2 on surgical and immunobiological variables in patients with colorectal cancer: a phase 2 study.
Author: Brivio, F|Lissoni, P|Barni, S|Tancini, G|Ardizzoia, A|Erba, L|Alderi, G|Nociti, V
PMID: 8095806
Journal: Cancer. 1993 Jun 1;71(11):3633-9.
Title: Short-duration in vitro interleukin-2-activated mononuclear cells for advanced cancer. A Hong Kong biotherapy pilot study trial.
Author: Yeung, A W|Pang, Y K|Tsang, Y C|Wong, S W|Leung, J S
PMID: 8387882
Journal: Clin Exp Immunol. 1993 Oct;94(1):4-10.
Title: Peri-operative modulation of cellular immunity in patients with colorectal cancer.
Author: Nichols, P H|Ramsden, C W|Ward, U|Trejdosiewicz, L K|Ambrose, N S|Primrose, J N
PMID: 8403515
Journal: Biotherapy. 1993;6(1):33-9.
Title: The expression and biological activity of IL-2 receptor on a human pancreas cancer cell line.
Author: Kawami, H|Yoshida, K|Yamaguchi, Y|Saeki, T|Toge, T
PMID: 8507543
Journal: Int J Oncol. 1993 Oct;3(4):763-8.
Title: Inhibition of proliferation, activation and function of human natural-killer-cells in-vitro by secreted products of lovo, a colorectal-cancer cell-line.
Author: Johnston, D|Allen, P|Newland, A|Williams, N
PMID: 21573430
Journal: Cancer Immunol Immunother. 1994 Jun;38(6):394-8.
Title: Alteration in lymphocyte phenotype associated with administration of adjuvant levamisole and 5-fluorouracil.
Author: Holcombe, R F|Stewart, R M|Betzing, K W|Kannan, K
PMID: 7515770
Journal: Immunol Lett. 1994 Feb;39(2):187-94.
Title: Binding of natural human IgM auto-antibodies to human tumor cell lines and stimulated normal T lymphocytes.
Author: Bohn, J|Roggenbuck, D|Settmacher, U|Docke, W|Volk, H D|Von Baehr, R|Jahn, S
PMID: 7912225
Journal: Anticancer Res. 1994 May-Jun;14(3A):963-8.
Title: Phenotypical and functional characteristics of tumor-infiltrating lymphocytes from colon carcinomas stimulated with rIL-2 and rIL-4 in vitro: comparison with lymphocytes of the normal colon mucosa and the peripheral blood.
Author: Wimmenauer, S|Keller, H|Rahner, S|Kirste, G|Von Bergwelt, M|Meyer, A|Von Kleist, S|Farthmann, E H
PMID: 8074499
Journal: Br J Cancer. 1994 Jun;69(6):1046-51.
Title: Functional role of IL-2 receptors on tumour-infiltrating lymphocytes.
Author: Trentin, L|Zambello, R|Bulian, P|Cerutti, A|Milani, A|Pirone, E|Nitti, D|Agostini, C|Semenzato, G
PMID: 8198969
Journal: Anticancer Drugs. 1995 Apr;6(2):250-8.
Title: Colorectal cell line suppression of lymphokine activated killer cell generation is reversed by suramin.
Author: Allen, P D|Johnston, D H|Macey, M G|Williams, N S|Newland, A C
PMID: 7540893
Journal: Eur Surg Res. 1995;27(4):258-68.
Title: Morphological and functional characteristics of tumor-infiltrating lymphocytes from human colorectal cancers after stimulation with rIL-2.
Author: Keller, H|Wimmenauer, S|Rahner, S|Reimer, P|von Kleist, S|Farthmann, E H
PMID: 7649213
Journal: Br J Surg. 1995 Jan;82(1):86-90.
Title: Modulation of the cytokine and acute-phase response to major surgery by recombinant interleukin-2.
Author: Deehan, D J|Heys, S D|Simpson, W|Broom, J|McMillan, D N|Eremin, O
PMID: 7881967
Journal: Ann Oncol. 1995 Dec;6(10):1011-7.
Title: Sequential biochemotherapy for metastatic colorectal cancer using fluorouracil, folinic acid, thymopentin and interleukin-2: clinical and immunological effects.
Author: Lopez, M|Di Lauro, L|Paoletti, G|Santini, S|Gandolfo, G M|Vitelli, G|Frasca, A M|Ameglio, F|Rasi, G|Garaci, E
PMID: 8750154
Journal: Cancer Biother Radiopharm. 1996 Dec;11(6):373-83.
Title: Necessity of biotherapeutic treatments inducing TH1 cell functions in colorectal cancer.
Author: Contasta, I|Pellegrini, P|Berghella, A M|Del Beato, T|Canossi, A|Di Rocco, M|Adorno, D|Casciani, C U
PMID: 10851498
Journal: Cancer Biother Radiopharm. 1996 Apr;11(2):113-8.
Title: Immunological directives for biotherapy improvement in the treatment of colorectal cancer.
Author: Pellegrini, P|Berghella, A M|Del Beato, T|Adorno, D|Casciani, C U
PMID: 10851527
Journal: Int J Cancer. 1997 Jul 3;72(1):142-8.
Title: Modulations of the effector function and cytokine production of human lymphocytes by secreted factors derived from colorectal-carcinoma cells.
Author: Luo, J S|Kammerer, R|Schultze, H|von Kleist, S
PMID: 9212235
Journal: Anticancer Res. 1997 Jul-Aug;17(4A):2395-400.
Title: Expression of CD44, ICAM-1 and N-CAM in colorectal cancer. Correlation with the tumor stage and the phenotypical characteristics of tumor-infiltrating lymphocytes.
Author: Wimmenauer, S|Keller, H|Ruckauer, K D|Rahner, S|Wolff-Vorbeck, G|Kirste, G|von Kleist, S|Farthman, E H
PMID: 9252653
Journal: J Cancer Res Clin Oncol. 1997;123(8):420-8.
Title: Interleukin-2-activated killer cell activity in colorectal tumor patients: evaluation of in vitro effects by prothymosin alpha1.
Author: Eckert, K|Grunberg, E|Immenschuh, P|Garbin, F|Kreuser, E D|Maurer, H R
PMID: 9292704
Journal: Shock. 1997 Dec;8(6):402-8.
Title: Modulation of immune response by blood transfusion: evidence for a differential effect of allogeneic and autologous blood in colorectal cancer surgery.
Author: Heiss, M M|Fraunberger, P|Delanoff, C|Stets, R|Allgayer, H|Strohlein, M A|Tarabichi, A|Faist, E|Jauch, K W|Schildberg, F W
PMID: 9421852
Journal: Cancer Immunol Immunother. 1997 Nov-Dec;45(3-4):193-7.
Title: Construction and biological activity of a recombinant bispecific single-chain antibody designed for therapy of minimal residual colorectal cancer.
Author: Kufer, P|Mack, M|Gruber, R|Lutterbuse, R|Zettl, F|Riethmuller, G
PMID: 9435872
Journal: Int J Immunopharmacol. 1997 Sep-Oct;19(9-10):493-500.
Title: Preclinical studies with prothymosin alpha1 on mononuclear cells from tumor patients.
Author: Eckert, K|Grunberg, E|Garbin, F|Maurer, H R
PMID: 9637344
Journal: Br J Cancer. 1998 Apr;77(7):1072-81.
Title: Interleukin 2 restores CD3-zeta chain expression but fails to generate tumour-specific lytic activity in tumour-infiltrating lymphocytes derived from human colorectal hepatic metastases.
Author: Yoong, K F|Adams, D H
PMID: 9569042
Journal: Int J Oncol. 1998 Dec;13(6):1105-15.
Title: Introduction of adhesive and costimulatory immune functions into tumor cells by infection with Newcastle Disease Virus.
Author: Haas, C|Ertel, C|Gerhards, R|Schirrmacher, V
PMID: 9824618
Journal: J Immunother. 1999 Jan;22(1):25-32.
Title: Local expression of cytokines in human colorectal carcinoma: evidence of specific interleukin-6 gene expression.
Author: Piancatelli, D|Romano, P|Sebastiani, P|Adorno, D|Casciani, C U
PMID: 9924696
Journal: Br J Cancer. 1999 Mar;79(7-8):1262-9.
Title: FasL is more frequently expressed in liver metastases of colorectal cancer than in matched primary carcinomas.
Author: Mann, B|Gratchev, A|Bohm, C|Hanski, M L|Foss, H D|Demel, G|Trojanek, B|Schmidt-Wolf, I|Stein, H|Riecken, E O|Buhr, H J|Hanski, C
PMID: 10098769
Journal: Hepatogastroenterology. 1999 Jan-Feb;46(25):220-7.
Title: Significance of pre-treatment immunological parameters in colorectal cancer patients with unresectable metastases to the liver.
Author: Zaloudik, J|Lauerova, L|Janakova, L|Talac, R|Simickova, M|Nekulova, M|Mikulikova, I|Kovarik, J|Sheard, M
PMID: 10228796
Journal: Eur J Gastroenterol Hepatol. 1999 Jul;11(7):769-74.
Title: Immunohistochemical analysis of inflammation in primary sclerosing cholangitis.
Author: Ponsioen, C Y|Kuiper, H|Ten Kate, F J|van Milligen de Wit, M|van Deventer, S J|Tytgat, G N
PMID: 10445798
Journal: Gut. 1999 Oct;45(4):593-8.
Title: Increased activation of lymphocytes infiltrating primary colorectal cancers following immunisation with the anti-idiotypic monoclonal antibody 105AD7.
Author: Maxwell-Armstrong, C A|Durrant, L G|Robins, R A|Galvin, A M|Scholefield, J H|Hardcastle, J D
PMID: 10486371
Journal: Colorectal Dis. 1999 Sep;1(5):286-91.
Title: Influence of peri-operative immunotherapy on serum cytokines and soluble cytokine receptors in patients undergoing surgery for colorectal cancer.
Author: Nichols|Ward|Gallati|Primrose
PMID: 23577850
Journal: Clin Cancer Res. 2001 Mar;7(3 Suppl):856s-864s.
Title: Protective immunity against human carcinoembryonic antigen (CEA) induced by an oral DNA vaccine in CEA-transgenic mice.
Author: Xiang, R|Silletti, S|Lode, H N|Dolman, C S|Ruehlmann, J M|Niethammer, A G|Pertl, U|Gillies, S D|Primus, F J|Reisfeld, R A
PMID: 11300483
Journal: J Immunol. 2001 Oct 15;167(8):4560-5.
Title: A dual-function DNA vaccine encoding carcinoembryonic antigen and CD40 ligand trimer induces T cell-mediated protective immunity against colon cancer in carcinoembryonic antigen-transgenic mice.
Author: Xiang, R|Primus, F J|Ruehlmann, J M|Niethammer, A G|Silletti, S|Lode, H N|Dolman, C S|Gillies, S D|Reisfeld, R A
PMID: 11591784
Journal: Cancer Immunol Immunother. 2002 Mar;51(1):53-7. Epub 2002 Jan 10.
Title: The presence of interleukin-2 receptor alpha in the serum of colorectal cancer patients is unlikely to result only from T cell up-regulation.
Author: Huang, Andy|Quinn, Helen|Glover, Clare|Henderson, Don C|Allen-Mersh, Timothy G
PMID: 11845260
Journal: Anticancer Res. 2002 Mar-Apr;22(2A):777-88.
Title: Modulation of innate immunological factors by STEALTH liposome-encapsulated tumor necrosis factor-alpha in a colon tumor xenograft model.
Author: Kim, Dong W|Andres, Melba L|Kajioka, Eric H|Dutta-Roy, Radha|Miller, Glen M|Seynhaeve, Ann L B|ten Hagen, Timo L M|Gridley, Daila S
PMID: 12014650
Journal: Cancer Res. 2002 Sep 15;62(18):5267-72.
Title: Inhibition of cytolytic T lymphocyte proliferation by autologous CD4+/CD25+ regulatory T cells in a colorectal carcinoma patient is mediated by transforming growth factor-beta.
Author: Somasundaram, Rajasekharan|Jacob, Lutz|Swoboda, Rolf|Caputo, Laura|Song, Hong|Basak, Saroj|Monos, Dimitri|Peritt, David|Marincola, Francesco|Cai, Dewei|Birebent, Brigitte|Bloome, Ellen|Kim, Jin|Berencsi, Klara|Mastrangelo, Michael|Herlyn, Dorothee
PMID: 12234995
Journal: Int J Clin Oncol. 2002 Oct;7(5):312-7.
Title: Serum soluble interleukin-2 receptor (IL-2R) and immunohistochemical staining of IL-2R/Tac antigen in colorectal cancer.
Author: Sakata, Hideto|Murakami, Saburo|Hirayama, Renzo
PMID: 12402066
Journal: Immunopharmacol Immunotoxicol. 2002 Nov;24(4):567-82.
Title: Helicobacter pylori organisms induce expression of activation and apoptotic surface markers on human lymphocytes and AGS cells: a cytofluorimetric evaluation.
Author: Lembo, Annalisa|Caradonna, Luigi|Magrone, Thea|Mastronardi, Maria Letizia|Caccavo, Domenico|Jirillo, Emilio|Amati, Luigi
PMID: 12510791
Journal: Eur J Immunol. 2002 Nov;32(11):3267-75.
Title: Depletion of CD25+ regulatory cells uncovers immune responses to shared murine tumor rejection antigens.
Author: Golgher, Denise|Jones, Emma|Powrie, Fiona|Elliott, Tim|Gallimore, Awen
PMID: 12555672
Journal: Am J Pathol. 2003 Feb;162(2):691-702.
Title: CD4+ CD25+ regulatory T lymphocytes inhibit microbially induced colon cancer in Rag2-deficient mice.
Author: Erdman, Susan E|Poutahidis, Theofilos|Tomczak, Michal|Rogers, Arlin B|Cormier, Kathleen|Plank, Benjamin|Horwitz, Bruce H|Fox, James G
PMID: 12547727
Journal: Cancer Res. 2003 Jun 1;63(11):2844-54.
Title: Murine dendritic cells pulsed with an anti-idiotype antibody induce antigen-specific protective antitumor immunity.
Author: Saha, Asim|Chatterjee, Sunil K|Foon, Kenneth A|Primus, F James|Bhattacharya-Chatterjee, Malaya
PMID: 12782590
Journal: Cancer Res. 2003 Sep 15;63(18):6042-50.
Title: CD4(+)CD25(+) regulatory lymphocytes require interleukin 10 to interrupt colon carcinogenesis in mice.
Author: Erdman, Susan E|Rao, Varada P|Poutahidis, Theofilos|Ihrig, Melanie M|Ge, Zhongming|Feng, Yan|Tomczak, Michal|Rogers, Arlin B|Horwitz, Bruce H|Fox, James G
PMID: 14522933
Journal: J Immunol. 2003 Dec 1;171(11):5931-9.
Title: CD4+/CD25+ regulatory cells inhibit activation of tumor-primed CD4+ T cells with IFN-gamma-dependent antiangiogenic activity, as well as long-lasting tumor immunity elicited by peptide vaccination.
Author: Casares, Noelia|Arribillaga, Laura|Sarobe, Pablo|Dotor, Javier|Lopez-Diaz de Cerio, Ascension|Melero, Ignacio|Prieto, Jesus|Borras-Cuesta, Francisco|Lasarte, Juan J
PMID: 14634104
Journal: Novartis Found Symp. 2004;256:149-52; discussion 152-7, 259-69.
Title: The influence of CD25+ cells on the generation of immunity to tumour cell lines in mice.
Author: Jones, Emma|Golgher, Denise|Simon, Anna Katharina|Dahm-Vicker, Michaela|Screaton, Gavin|Elliott, Tim|Gallimore, Awen
PMID: 15027488
Journal: Med Sci Monit. 2004 Apr;10(4):BR96-104.
Title: Yogurt feeding inhibits promotion and progression of experimental colorectal cancer.
Author: de Moreno de Leblanc, Alejandra|Perdigon, Gabriela
PMID: 15039638
Journal: Br J Surg. 2004 Apr;91(4):469-75.
Title: Tumour-infiltrating lymphocytes in colorectal cancer with microsatellite instability are activated and cytotoxic.
Author: Phillips, S M|Banerjea, A|Feakins, R|Li, S R|Bustin, S A|Dorudi, S
PMID: 15048750
Journal: Zhejiang Da Xue Xue Bao Yi Xue Ban. 2004 Mar;33(2):118-20.
Title: [Expression of leucocyte cell-surface antigens on colon cancer cell line HR8348].
Author: Yang, Shi-long|Tang, Yon-min|Shen, Hong-qiang|Qian, Bo-qin|Song, Hua|Shi, Shu-wen|Ning, Bo-tao|Chen, Ying-hu|Xu, Wei-qun
PMID: 15067730
Journal: Cancer Res. 2004 Jul 15;64(14):4995-5003.
Title: Dendritic cells pulsed with an anti-idiotype antibody mimicking carcinoembryonic antigen (CEA) can reverse immunological tolerance to CEA and induce antitumor immunity in CEA transgenic mice.
Author: Saha, Asim|Chatterjee, Sunil K|Foon, Kenneth A|Primus, F James|Sreedharan, Sunil|Mohanty, Kartik|Bhattacharya-Chatterjee, Malaya
PMID: 15256474
Journal: J Transl Med. 2005 Jan 28;3(1):5.
Title: The changes of CD4+CD25+/CD4+ proportion in spleen of tumor-bearing BALB/c mice.
Author: Liu, Ji-Yan|Zhang, Xiao-Shi|Ding, Ya|Peng, Rui-Qing|Cheng, Xia|Zhang, Nian-Hua|Xia, Jian-Chuan|Zeng, Yi-Xin
PMID: 15679891
Journal: Cancer Immunol Immunother. 2005 Jan;54(1):78-86.
Title: Large intestine intraepithelial lymphocytes from Apc+/+ and Apc+/Min mice and their modulation by indigestible carbohydrates: the IL-15/IL-15R alpha complex and CD4+ CD25+ T cells are the main targets.
Author: Forest, Virginie|Pierre, Fabrice|Bassonga, Euphemie|Meflah, Khaled|Menanteau, Jean
PMID: 15693142
Journal: Cancer Res. 2005 May 15;65(10):3998-4004.
Title: CD4+CD25+ regulatory lymphocytes induce regression of intestinal tumors in ApcMin/+ mice.
Author: Erdman, Susan E|Sohn, Jane J|Rao, Varada P|Nambiar, Prashant R|Ge, Zhongming|Fox, James G|Schauer, David B
PMID: 15899788
Journal: Mol Immunol. 2006 Mar;43(8):1129-43.
Title: MT110: a novel bispecific single-chain antibody construct with high efficacy in eradicating established tumors.
Author: Brischwein, Klaus|Schlereth, Bernd|Guller, Benjamin|Steiger, Carola|Wolf, Andreas|Lutterbuese, Ralf|Offner, Sonja|Locher, Mathias|Urbig, Thomas|Raum, Tobias|Kleindienst, Petra|Wimberger, Pauline|Kimmig, Rainer|Fichtner, Iduna|Kufer, Peter|Hofmeister, Robe
PMID: 16139892
Journal: PLoS One. 2006 Dec 27;1:e129.
Title: CD4+CD25+FOXP3+ regulatory T cells suppress anti-tumor immune responses in patients with colorectal cancer.
Author: Clarke, Sarah L|Betts, Gareth J|Plant, Andrea|Wright, Kate L|El-Shanawany, Tariq M|Harrop, Richard|Torkington, Jared|Rees, Brian I|Williams, Geraint T|Gallimore, Awen M|Godkin, Andrew J
PMID: 17205133
Journal: Clin Cancer Res. 2007 Feb 1;13(3):958-64.
Title: A pilot study of CTLA-4 blockade after cancer vaccine failure in patients with advanced malignancy.
Author: O'Mahony, Deirdre|Morris, John C|Quinn, Cate|Gao, Wendy|Wilson, Wyndham H|Gause, Barry|Pittaluga, Stefania|Neelapu, Sattva|Brown, Margaret|Fleisher, Thomas A|Gulley, James L|Schlom, Jeffrey|Nussenblatt, Robert|Albert, Paul|Davis, Thomas A|Lowy, Israel|Pet
PMID: 17289891
Journal: Cancer Immun. 2007 Mar 28;7:7.
Title: Increased frequency of regulatory T cells in peripheral blood and tumour infiltrating lymphocytes in colorectal cancer patients.
Author: Ling, Khoon Lin|Pratap, Sarah E|Bates, Gaynor J|Singh, Baljit|Mortensen, Neil J|George, Bruce D|Warren, Bryan F|Piris, Juan|Roncador, Giovanna|Fox, Stephen B|Banham, Alison H|Cerundolo, Vincenzo
PMID: 17388261
Journal: Vopr Onkol. 2007;53(1):49-53.
Title: [Declining mitogen-induced polyclonal activity of peripheral blood lymphocytes as an index of immunosuppression involved in different neoplasms].
Author: Oleinik, E K|Oleinik, V M|Nazarov, P G|Moiseenko, V M
PMID: 17649734
Journal: Clin Cancer Res. 2007 Aug 1;13(15 Pt 1):4528-37.
Title: Different forms of helper tolerance to carcinoembryonic antigen: ignorance and regulation.
Author: Pickford, Wendy J|Watson, Angus J M|Barker, Robert N
PMID: 17671139
Journal: Cancer Res. 2007 Oct 15;67(20):10058-66.
Title: Live attenuated Listeria monocytogenes effectively treats hepatic colorectal cancer metastases and is strongly enhanced by depletion of regulatory T cells.
Author: Yoshimura, Kiyoshi|Laird, Lindsay S|Chia, Christina Y|Meckel, Kristen F|Slansky, Jill E|Thompson, John M|Jain, Ajay|Pardoll, Drew M|Schulick, Richard D
PMID: 17942940
Journal: Uirusu. 2007 Jun;57(1):19-27.
Title: [Anticancer immunotherapy using inactivated Sendai virus particles].
Author: Kurooka, Masayuki|Kaneda, Yasufumi
PMID: 18040151
Journal: Ann Surg Oncol. 2008 Aug;15(8):2310-7.
Title: Detection and functional analysis of tumor infiltrating T-lymphocytes (TIL) in liver metastases from colorectal cancer.
Author: Wagner, Philipp|Koch, Moritz|Nummer, Daniel|Palm, Sylvia|Galindo, Luis|Autenrieth, Daniel|Rahbari, Nuh|Schmitz-Winnenthal, Friedrich H|Schirrmacher, Volker|Buchler, Markus W|Beckhove, Philipp|Weitz, Jurgen
PMID: 18521684
Journal: Cancer Immun. 2008 Jun 12;8:10.
Title: Dysregulation in immune functions is reflected in tumor cell cytotoxicity by peripheral blood mononuclear cells from head and neck squamous cell carcinoma patients.
Author: Bose, Anamika|Chakraborty, Tathagata|Chakraborty, Krishnendu|Pal, Smarajit|Baral, Rathindranath
PMID: 18547033
Journal: Carcinogenesis. 2008 Sep;29(9):1799-806.
Title: Ginkgo biloba extract EGb 761 has anti-inflammatory properties and ameliorates colitis in mice by driving effector T cell apoptosis.
Author: Kotakadi, Venkata S|Jin, Yu|Hofseth, Anne B|Ying, Lei|Cui, Xiangli|Volate, Suresh|Chumanevich, Alexander|Wood, Patricia A|Price, Robert L|McNeal, Anna|Singh, Udai P|Singh, Narendra P|Nagarkatti, Mitzi|Nagarkatti, Prakash S|Matesic, Lydia E|Auclair, Karine
PMID: 18567620
Journal: Clin Cancer Res. 2008 Aug 1;14(15):4883-90.
Title: T-cell responses to survivin in cancer patients undergoing radiation therapy.
Author: Schaue, Dorthe|Comin-Anduix, Begonya|Ribas, Antoni|Zhang, Li|Goodglick, Lee|Sayre, James W|Debucquoy, Annelies|Haustermans, Karin|McBride, William H
PMID: 18676762
Journal: Gut. 2009 Apr;58(4):520-9.
Title: Identification of CD8+CD25+Foxp3+ suppressive T cells in colorectal cancer tissue.
Author: Chaput, N|Louafi, S|Bardier, A|Charlotte, F|Vaillant, J-C|Menegaux, F|Rosenzwajg, M|Lemoine, F|Klatzmann, D|Taieb, J
PMID: 19022917
Journal: Fam Cancer. 2009;8(3):231-9.
Title: Lymphocyte recruitment into the tumor site is altered in patients with MSI-H colon cancer.
Author: Drescher, Kristen M|Sharma, Poonam|Watson, Patrice|Gatalica, Zoran|Thibodeau, Stephen N|Lynch, Henry T
PMID: 19165625
Journal: Clin Cancer Res. 2009 Feb 1;15(3):960-70.
Title: B7 blockade alters the balance between regulatory T cells and tumor-reactive T cells for immunotherapy of cancer.
Author: Zhou, Penghui|Zheng, Xincheng|Zhang, Huiming|Liu, Yang|Zheng, Pan
PMID: 19188167
Journal: Mol Med Rep. 2009 Sep-Oct;2(5):773-7.
Title: Anti-tumor effect of combining CC chemokine 22 and an anti-CD25 antibody on myeloma cells implanted subcutaneously into mice.
Author: Cho, Seiji|Koizumi, Keiichi|Takeno, Nobuhiro|Kato, Shinichiro|Yamada, Miyuki|Hashimoto, Isaya|Sakurai, Hiroaki|Tsukada, Kazuhiro|Saiki, Ikuo
PMID: 21475900
Journal: Int J Cancer. 2010 Apr 1;126(7):1666-74.
Title: Blockade of TGF-beta enhances tumor vaccine efficacy mediated by CD8(+) T cells.
Author: Takaku, Shun|Terabe, Masaki|Ambrosino, Elena|Peng, Judy|Lonning, Scott|McPherson, John M|Berzofsky, Jay A
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Journal: Eur J Immunol. 2010 Apr;40(4):1011-21.
Title: Targeted inhibition of IL-10-secreting CD25- Treg via p38 MAPK suppression in cancer immunotherapy.
Author: Ohkusu-Tsukada, Kozo|Toda, Masahiro|Udono, Heiichiro|Kawakami, Yutaka|Takahashi, Kimimasa
PMID: 20127675
Journal: Int J Clin Oncol. 2010 Apr;15(2):145-52.
Title: PSK may suppress CD57(+) T cells to improve survival of advanced gastric cancer patients.
Author: Akagi, Junji|Baba, Hideo
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Journal: Scand J Immunol. 2010 Feb;71(2):70-82.
Title: Combination of CTL-associated antigen-4 blockade and depletion of CD25 regulatory T cells enhance tumour immunity of dendritic cell-based vaccine in a mouse model of colon cancer.
Author: Saha, Asim|Chatterjee, S K
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Journal: Clin Exp Immunol. 2010 Jul 1;161(1):81-8.
Title: Survival in rectal cancer is predicted by T cell infiltration of tumour-associated lymphoid nodules.
Author: McMullen, T P W|Lai, R|Dabbagh, L|Wallace, T M|de Gara, C J
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Journal: Clin Cancer Res. 2010 May 15;16(10):2781-91.
Title: Two distinct mechanisms of augmented antitumor activity by modulation of immunostimulatory/inhibitory signals.
Author: Mitsui, Jun|Nishikawa, Hiroyoshi|Muraoka, Daisuke|Wang, Linan|Noguchi, Takuro|Sato, Eiichi|Kondo, Satoshi|Allison, James P|Sakaguchi, Shimon|Old, Lloyd J|Kato, Takuma|Shiku, Hiroshi
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Journal: Zhongguo Zhong Xi Yi Jie He Za Zhi. 2010 Mar;30(3):280-2.
Title: [Effect of shenqi fuzheng injection combined with chemotherapy in treating colorectal cancer].
Author: Zhang, Yan|Guo, Ling-li|Zhao, Shi-peng
PMID: 20535927
Journal: Cancer Res. 2010 Oct 15;70(20):7960-9.
Title: Dietary fish oil alters T lymphocyte cell populations and exacerbates disease in a mouse model of inflammatory colitis.
Author: Woodworth, Hillary L|McCaskey, Sarah J|Duriancik, David M|Clinthorne, Jonathan F|Langohr, Ingeborg M|Gardner, Elizabeth M|Fenton, Jenifer I
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Journal: J Immunol. 2011 Jan 15;186(2):807-15.
Title: Successful colon cancer eradication after chemoimmunotherapy is associated with profound phenotypic change of intratumoral myeloid cells.
Author: Medina-Echeverz, Jose|Fioravanti, Jessica|Zabala, Maider|Ardaiz, Nuria|Prieto, Jesus|Berraondo, Pedro
PMID: 21148040
Journal: Gastroenterology. 2011 Jun;140(7):2019-30.
Title: Human colonic myofibroblasts promote expansion of CD4+ CD25high Foxp3+ regulatory T cells.
Author: Pinchuk, Irina V|Beswick, Ellen J|Saada, Jamal I|Boya, Gushyalatha|Schmitt, David|Raju, Gottumukkala S|Brenmoehl, Julia|Rogler, Gerhard|Reyes, Victor E|Powell, Don W
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Journal: Cancer Gene Ther. 2011 Dec;18(12):850-8.
Title: Inhibition and promotion of tumor growth with adeno-associated virus carcinoembryonic antigen vaccine and Toll-like receptor agonists.
Author: Triozzi, P L|Aldrich, W|Ponnazhagan, S
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Journal: J Clin Immunol. 2011 Dec;31(6):1095-104.
Title: Behavior of circulating CD4+CD25+Foxp3+ regulatory T cells in colon cancer patients undergoing surgery.
Author: Sellitto, Ausilia|Galizia, Gennaro|De Fanis, Umberto|Lieto, Eva|Zamboli, Anna|Orditura, Michele|De Vita, Ferdinando|Giunta, Riccardo|Lucivero, Giacomo|Romano, Ciro
PMID: 21915633
Journal: PLoS One. 2012;7(1):e30422.
Title: In vivo expansion of naive CD4+ CD25(high) FOXP3+ regulatory T cells in patients with colorectal carcinoma after IL-2 administration.
Author: Beyer, Marc|Schumak, Beatrix|Weihrauch, Martin R|Andres, Bettina|Giese, Thomas|Endl, Elmar|Knolle, Percy A|Classen, Sabine|Limmer, Andreas|Schultze, Joachim L
PMID: 22276195
Journal: PLoS One. 2012;7(2):e30695.
Title: Accumulation of CCR4(+)CTLA-4 FOXP3(+)CD25(hi) regulatory T cells in colon adenocarcinomas correlate to reduced activation of conventional T cells.
Author: Svensson, Helena|Olofsson, Veronica|Lundin, Samuel|Yakkala, Chakradhar|Bjorck, Stellan|Borjesson, Lars|Gustavsson, Bengt|Quiding-Jarbrink, Marianne
PMID: 22319577
Journal: J Immunotoxicol. 2012 Oct-Dec;9(4):368-73.
Title: In vitro selective depletion of CD4(+)CD25(+) regulatory T-cells from PBMC using anti-tac-SAP.
Author: Akbari, Akbar|Rezaei, Abbas
PMID: 22506556
Journal: Hepatology. 2012 Nov;56(5):1924-33.
Title: Liver sinusoidal endothelial cells contribute to CD8 T cell tolerance toward circulating carcinoembryonic antigen in mice.
Author: Hochst, Bastian|Schildberg, Frank A|Bottcher, Jan|Metzger, Christina|Huss, Sebastian|Turler, Andreas|Overhaus, Markus|Knoblich, Andreas|Schneider, Berthold|Pantelis, Dimitrios|Kurts, Christian|Kalff, Jorg C|Knolle, Percy|Diehl, Linda
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Journal: Radiother Oncol. 2012 Jul;104(1):131-8.
Title: Circulating regulatory T cells of cancer patients receiving radiochemotherapy may be useful to individualize cancer treatment.
Author: Schmidt, Manuel A|Fortsch, Claudia|Schmidt, Manfred|Rau, Tilman T|Fietkau, Rainer|Distel, Luitpold V
PMID: 22682747
Journal: Hepatology. 2013 Jan;57(1):183-94.
Title: Activated tumor-infiltrating CD4+ regulatory T cells restrain antitumor immunity in patients with primary or metastatic liver cancer.
Author: Pedroza-Gonzalez, Alexander|Verhoef, Cornelis|Ijzermans, Jan N M|Peppelenbosch, Maikel P|Kwekkeboom, Jaap|Verheij, Joanne|Janssen, Harry L A|Sprengers, Dave
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Journal: Int J Colorectal Dis. 2013 Nov;28(11):1591-3.
Title: Impact of preoperative serum interleukin-2 receptor alpha levels on survival and its correlation with clinicopathological parameters in colorectal cancer.
Author: Liu, Xiaomei|Zhang, Yinxu|Zhang, Junhua|Zhu, Zhitu|Ha, Minwen|Liu, Chunying
PMID: 23340854
Journal: Cytotherapy. 2013 Apr;15(4):481-91.
Title: Ex vivo characterization of gammadelta T-cell repertoire in patients after adoptive transfer of Vgamma9Vdelta2 T cells expressing the interleukin-2 receptor beta-chain and the common gamma-chain.
Author: Izumi, Takamichi|Kondo, Makoto|Takahashi, Takuya|Fujieda, Nao|Kondo, Atsushi|Tamura, Naohisa|Murakawa, Tomohiro|Nakajima, Jun|Matsushita, Hirokazu|Kakimi, Kazuhiro
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Journal: PLoS One. 2013;8(3):e58006.
Title: Tim-3 expression defines regulatory T cells in human tumors.
Author: Yan, Jing|Zhang, Yi|Zhang, Jing-Ping|Liang, Jing|Li, Lian|Zheng, Limin
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Journal: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2013 Apr;35(2):155-60.
Title: [Changes of lymphocyte subsets before and after chemotherapy in colorectal carcinoma patients].
Author: Zhang, Guo-qing|Zhao, Hong|Wen, Xin-yu|Li, Jin-yu|Wu, Liang-liang|Jiao, Shun-chang
PMID: 23643003
Journal: Mucosal Immunol. 2014 Mar;7(2):428-39.
Title: Highly prevalent colorectal cancer-infiltrating LAP(+) Foxp3(-) T cells exhibit more potent immunosuppressive activity than Foxp3(+) regulatory T cells.
Author: Scurr, M|Ladell, K|Besneux, M|Christian, A|Hockey, T|Smart, K|Bridgeman, H|Hargest, R|Phillips, S|Davies, M|Price, D|Gallimore, A|Godkin, A
PMID: 24064667
Journal: J Immunother. 2014 Jan;37(1):1-7.
Title: CTLA-4 blockade enhances antitumor immunity of intratumoral injection of immature dendritic cells into irradiated tumor in a mouse colon cancer model.
Author: Son, Cheol-Hun|Bae, Jae-Ho|Shin, Dong-Yeok|Lee, Hong-Rae|Choi, Yoo-Jin|Jo, Wol-Soon|Ho Jung, Min|Kang, Chi-Dug|Yang, Kwangmo|Park, You-Soo
PMID: 24316550
Journal: J Immunotoxicol. 2014 Oct;11(4):328-36.
Title: Norm- and hypo-fractionated radiotherapy is capable of activating human dendritic cells.
Author: Kulzer, Lorenz|Rubner, Yvonne|Deloch, Lisa|Allgauer, Andrea|Frey, Benjamin|Fietkau, Rainer|Dorrie, Jan|Schaft, Niels|Gaipl, Udo S
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Journal: AIDS Res Hum Retroviruses. 2014 Jul;30(7):677-84.
Title: HIV infection accelerates gastrointestinal tumor outgrowth in NSG-HuPBL mice.
Author: Lu, Rong|Wu, Shaoping|Zhang, Yongguo|Xia, Yinglin|Huelsmann, Erica J|Lacek, Andrew T|Nabatiyan, Arman|Richards, Maureen H|Narasipura, Srinivas D|Lutgen, Victoria|Chen, Honglei|Kaufman, Howard L|Chen, Di|Al-Harthi, Lena|Zloza, Andrew|Sun, Jun
PMID: 24593860
Journal: Cancer Immunol Res. 2014 Jun;2(6):568-80.
Title: TLR7 ligand augments GM-CSF-initiated antitumor immunity through activation of plasmacytoid dendritic cells.
Author: Narusawa, Megumi|Inoue, Hiroyuki|Sakamoto, Chika|Matsumura, Yumiko|Takahashi, Atsushi|Inoue, Tomoko|Watanabe, Ayumi|Miyamoto, Shohei|Miura, Yoshie|Hijikata, Yasuki|Tanaka, Yoshihiro|Inoue, Makoto|Takayama, Koichi|Okazaki, Toshihiko|Hasegawa, Mamoru|Nakani
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Journal: J Immunother Cancer. 2014 Nov 18;2(1):38.
Title: Detailed characterization of tumor infiltrating lymphocytes in two distinct human solid malignancies show phenotypic similarities.
Author: Kovacsovics-Bankowski, Magdalena|Chisholm, Lana|Vercellini, Jonna|Tucker, Christopher G|Montler, Ryan|Haley, Daniel|Newell, Philippa|Ma, Jun|Tseng, Paul|Wolf, Ronald|Vetto, John T|Hammill, Chet|Hansen, Paul|Weinberg, Andrew D
PMID: 25436113
Journal: PLoS One. 2014 Dec 26;9(12):e116169.
Title: The influence of the CHIEF pathway on colorectal cancer-specific mortality.
Author: Slattery, Martha L|Lundgreen, Abbie
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Journal: Expert Opin Ther Targets. 2015 Feb;19(2):147-61.
Title: Novel expression of Neuropilin 1 on human tumor-infiltrating lymphocytes in colorectal cancer liver metastases.
Author: Chaudhary, Belal|Elkord, Eyad
PMID: 25351619
Journal: J Immunol Methods. 2015 Jan;416:59-68.
Title: Surface profiles of live colorectal cancer cells and tumor infiltrating lymphocytes from surgical samples correspond to prognostic categories.
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Journal: J Transl Med. 2015 Feb 1;13:47.
Title: Tumor-induced myeloid-derived suppressor cells promote tumor progression through oxidative metabolism in human colorectal cancer.
Author: OuYang, Li-Ying|Wu, Xiao-Jun|Ye, Shu-Biao|Zhang, Rong-Xin|Li, Ze-Lei|Liao, Wei|Pan, Zhi-Zhong|Zheng, Li-Min|Zhang, Xiao-Shi|Wang, Zhong|Li, Qing|Ma, Gang|Li, Jiang
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Journal: Br J Cancer. 2015 Mar 17;112(6):1088-97.
Title: Cytokine profile and prognostic significance of high neutrophil-lymphocyte ratio in colorectal cancer.
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Journal: Int J Radiat Oncol Biol Phys. 2015 Jun 1;92(2):390-8.
Title: Combination effect of regulatory T-cell depletion and ionizing radiation in mouse models of lung and colon cancer.
Author: Son, Cheol-Hun|Bae, Jae-Ho|Shin, Dong-Yeok|Lee, Hong-Rae|Jo, Wol-Soon|Yang, Kwangmo|Park, You-Soo
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Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2015 Apr;18(4):361-4.
Title: [Relationship between CD4(+)CD25(High)CD127(low) regularly T cells in the peripheral blood and tumor regression after neoadjuvant therapy in patients with rectal cancer].
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Journal: Cancer. 2015 Sep 1;121(17):2968-75.
Title: Joint prognostic effect of obesity and chronic systemic inflammation in patients with metastatic colorectal cancer.
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Journal: Int Immunopharmacol. 2015 Jul;27(1):110-21.
Title: Artesunate down-regulates immunosuppression from colorectal cancer Colon26 and RKO cells in vitro by decreasing transforming growth factor beta1 and interleukin-10.
Author: Cui, Cheng|Feng, Helin|Shi, Xinli|Wang, Yazhuo|Feng, Zhangying|Liu, Jingli|Han, Zhipeng|Fu, Junqiu|Fu, Zhanjiang|Tong, Hui
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Journal: Cancer Immunol Immunother. 2015 Sep;64(9):1185-91.
Title: Preferential expansion of pro-inflammatory Tregs in human non-small cell lung cancer.
Author: Phillips, Joseph D|Knab, Lawrence M|Blatner, Nichole R|Haghi, Leila|DeCamp, Malcolm M|Meyerson, Shari L|Heiferman, Michael J|Heiferman, Jeffrey R|Gounari, Fotini|Bentrem, David J|Khazaie, Khashayarsha
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Journal: J Immunol. 2015 Aug 15;195(4):1883-90.
Title: Innate Response to Human Cancer Cells with or without IL-2 Receptor Common gamma-Chain Function in NOD Background Mice Lacking Adaptive Immunity.
Author: Nishime, Chiyoko|Kawai, Kenji|Yamamoto, Takehiro|Katano, Ikumi|Monnai, Makoto|Goda, Nobuhito|Mizushima, Tomoko|Suemizu, Hiroshi|Nakamura, Masato|Murata, Mitsuru|Suematsu, Makoto|Wakui, Masatoshi
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Title: Accumulation of FoxP3+ T regulatory cells in the tumor microenvironment of human colorectal adenomas.
Author: Hua, Wei|Yuan, Aping|Zheng, Wei|Li, Can|Cui, Jing|Pang, Zhigang|Zhang, Li|Li, Zhenfeng|Goll, Rasmus|Cui, Guanglin
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Journal: Toxins (Basel). 2016 Jan 19;8(1). pii: toxins8010027.
Title: Preventive Effects of Bee Venom Derived Phospholipase A(2) on Oxaliplatin-Induced Neuropathic Pain in Mice.
Author: Li, Dongxing|Kim, Woojin|Shin, Dasom|Jung, Yongjae|Bae, Hyunsu|Kim, Sun Kwang
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Journal: Oncol Lett. 2016 Mar;11(3):1707-1712.
Title: Bone morphogenetic protein 7 is associated with the nodal invasion of colon cancer.
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Journal: Front Oncol. 2016 Mar 7;6:50.
Title: Enrichment of Inflammatory IL-17 and TNF-alpha Secreting CD4(+) T Cells within Colorectal Tumors despite the Presence of Elevated CD39(+) T Regulatory Cells and Increased Expression of the Immune Checkpoint Molecule, PD-1.
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Title: Xenogeneic cell-based vaccine therapy for colorectal cancer: Safety, association of clinical effects with vaccine-induced immune responses.
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Journal: Tumour Biol. 2016 Nov;37(11):14659-14666.
Title: Determination of a CD4(+)CD25(-)FoxP3(+) T cells subset in tumor-draining lymph nodes of colorectal cancer secreting IL-2 and IFN-gamma.
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Journal: Dis Markers. 2016;2016:9602472.
Title: Proteomic Approaches to Biomarker Discovery in Cutaneous T-Cell Lymphoma.
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Journal: Oncotarget. 2017 Jun 20;8(25):41401-41411.
Title: Trans-scirpusin A showed antitumor effects via autophagy activation and apoptosis induction of colorectal cancer cells.
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Journal: Clin Exp Immunol. 2018 Jan;191(1):32-41.
Title: An increased CD25-positive intestinal regulatory T lymphocyte population is dependent upon Cox-2 activity in the Apc(min/+) model.
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Journal: Sci Signal. 2018 Jan 2;11(511). pii: 11/511/eaan0790.
Title: Blockade of TNFR2 signaling enhances the immunotherapeutic effect of CpG ODN in a mouse model of colon cancer.
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Journal: Clin Exp Pharmacol Physiol. 2018 Oct;45(10):1002-1009.
Title: Co-expression of LAG3 and TIM3 identifies a potent Treg population that suppresses macrophage functions in colorectal cancer patients.
Author: Ma, Qiang|Liu, Junning|Wu, Guoliang|Teng, Mujian|Wang, Shaoxuan|Cui, Meng|Li, Yuantao
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