Primary Site >> Colorectal Cancer
Gene >> IL21
| 1. | |||||||||||
| Journal: | Cancer Gene Ther. 2003 Mar;10(3):187-92. | ||||||||||
| Title: | Expression of the interleukin-21 gene in murine colon carcinoma cells generates systemic immunity in the inoculated hosts. | ||||||||||
| Author: | Ugai, Shin-ichi|Shimozato, Osamu|Kawamura, Kiyoko|Wang, Yan-Qing|Yamaguchi, Taketo|Saisho, Hiromitsu|Sakiyama, Shigeru|Tagawa, Masatoshi | ||||||||||
| PMID: | 12637939 | ||||||||||
| 2. | |||||||||||
| Journal: | J Immunol. 2004 Feb 1;172(3):1540-7. | ||||||||||
| Title: | IL-21 induces tumor rejection by specific CTL and IFN-gamma-dependent CXC chemokines in syngeneic mice. | ||||||||||
| Author: | Di Carlo, Emma|Comes, Alberto|Orengo, Anna Maria|Rosso, Ombretta|Meazza, Raffaella|Musiani, Piero|Colombo, Mario P|Ferrini, Silvano | ||||||||||
| PMID: | 14734732 | ||||||||||
| 3. | |||||||||||
| Journal: | World J Gastroenterol. 2007 Jun 14;13(22):3063-70. | ||||||||||
| Title: | In situ tumor vaccination with adenovirus vectors encoding measles virus fusogenic membrane proteins and cytokines. | ||||||||||
| Author: | Hoffmann, Dennis|Bayer, Wibke|Wildner, Oliver | ||||||||||
| PMID: | 17589921 | ||||||||||
| 4. | |||||||||||
| Journal: | J Immunol. 2009 Dec 1;183(11):7326-36. | ||||||||||
| Title: | Endogenous IL-21 restricts CD8+ T cell expansion and is not required for tumor immunity. | ||||||||||
| Author: | Sondergaard, Henrik|Coquet, Jonathan M|Uldrich, Adam P|McLaughlin, Nicole|Godfrey, Dale I|Sivakumar, Pallavur V|Skak, Kresten|Smyth, Mark J | ||||||||||
| PMID: | 19915059 | ||||||||||
| 5. | |||||||||||
| Journal: | J Biomed Mater Res B Appl Biomater. 2011 Oct;99(1):70-80. | ||||||||||
| Title: | Synthesis and efficient hepatocyte targeting of galactosylated chitosan as a gene carrier in vitro and in vivo. | ||||||||||
| Author: | Cheng, Mingrong|Li, Qing|Wan, Tao|Hong, Xiaowu|Chen, Houxiang|He, Bing|Cheng, Zhijian|Xu, Hongzhi|Ye, Tao|Zha, Bingbing|Wu, Jingbo|Zhou, Runjiao | ||||||||||
| PMID: | 21656667 | ||||||||||
| 6. | |||||||||||
| Journal: | Dig Dis. 2011;29(2):154-65. | ||||||||||
| Title: | Nutritional influences in selected gastrointestinal diseases. | ||||||||||
| Author: | Lakatos, Peter Laszlo|Kiss, Lajos S|Miheller, Pal | ||||||||||
| PMID: | 21734379 | ||||||||||
| 7. | |||||||||||
| Journal: | J Exp Med. 2011 Oct 24;208(11):2279-90. | ||||||||||
| Title: | Involvement of interleukin-21 in the regulation of colitis-associated colon cancer. | ||||||||||
| Author: | Stolfi, Carmine|Rizzo, Angelamaria|Franze, Eleonora|Rotondi, Angela|Fantini, Massimo Claudio|Sarra, Massimiliano|Caruso, Roberta|Monteleone, Ivan|Sileri, Pierpaolo|Franceschilli, Luana|Caprioli, Flavio|Ferrero, Stefano|MacDonald, Thomas T|Pallone, Frances | ||||||||||
| PMID: | 21987656 | ||||||||||
| 8. | |||||||||||
| Journal: | Oncoimmunology. 2012 May 1;1(3):351-354. | ||||||||||
| Title: | Interleukin-21 in cancer immunotherapy: Friend or foe? | ||||||||||
| Author: | Stolfi, Carmine|Pallone, Francesco|Macdonald, Thomas T|Monteleone, Giovanni | ||||||||||
| PMID: | 22737612 | ||||||||||
| 9. | |||||||||||
| Journal: | Cancer Res. 2012 Sep 1;72(17):4340-50. | ||||||||||
| Title: | Transcription factor NFATc2 controls the emergence of colon cancer associated with IL-6-dependent colitis. | ||||||||||
| Author: | Gerlach, Katharina|Daniel, Carolin|Lehr, Hans A|Nikolaev, Alexei|Gerlach, Thomas|Atreya, Raja|Rose-John, Stefan|Neurath, Markus F|Weigmann, Benno | ||||||||||
| PMID: | 22738913 | ||||||||||
| 10. | |||||||||||
| Journal: | Oncoimmunology. 2012 Jul 1;1(4):537-538. | ||||||||||
| Title: | Interleukin 21 impairs tumor immunosurveillance of colitis-associated colorectal cancer. | ||||||||||
| Author: | Kesselring, Rebecca|Jauch, Dominik|Fichtner-Feigl, Stefan | ||||||||||
| PMID: | 22754778 | ||||||||||
| 11. | |||||||||||
| Journal: | BMC Cancer. 2012 Sep 21;12:418. | ||||||||||
| Title: | The changes of Th17 cells and the related cytokines in the progression of human colorectal cancers. | ||||||||||
| Author: | Wang, Jiansheng|Xu, Kaiyu|Wu, Jing|Luo, Chenghua|Li, Yuchen|Wu, Xuebin|Gao, Hong|Feng, Guosheng|Yuan, Bao-Zhu | ||||||||||
| PMID: | 22994684 | ||||||||||
| 12. | |||||||||||
| Journal: | Int Immunol. 2013 Jan;25(1):35-44. | ||||||||||
| Title: | Interplay between T(h)1 and T(h)17 effector T-cell pathways in the pathogenesis of spontaneous colitis and colon cancer in the Galphai2-deficient mouse. | ||||||||||
| Author: | Gotlind, Yu-Yuan|Fritsch Fredin, Maria|Kumawat, Ashok Kumar|Strid, Hilja|Willen, Roger|Rangel, Ignacio|Bland, Paul W|Hornquist, Elisabeth Hultgren | ||||||||||
| PMID: | 22962436 | ||||||||||
| 13. | |||||||||||
| Journal: | Immunity. 2013 Oct 17;39(4):782-95. | ||||||||||
| Title: | Spatiotemporal dynamics of intratumoral immune cells reveal the immune landscape in human cancer. | ||||||||||
| Author: | Bindea, Gabriela|Mlecnik, Bernhard|Tosolini, Marie|Kirilovsky, Amos|Waldner, Maximilian|Obenauf, Anna C|Angell, Helen|Fredriksen, Tessa|Lafontaine, Lucie|Berger, Anne|Bruneval, Patrick|Fridman, Wolf Herman|Becker, Christoph|Pages, Franck|Speicher, Michael | ||||||||||
| PMID: | 24138885 | ||||||||||
| 14. | |||||||||||
| Journal: | Oncoimmunology. 2013 Dec 1;2(12):e26617. | ||||||||||
| Title: | Role of TH17 cytokines in the control of colorectal cancer. | ||||||||||
| Author: | De Simone, Veronica|Pallone, Francesco|Monteleone, Giovanni|Stolfi, Carmine | ||||||||||
| PMID: | 24498548 | ||||||||||
| 15. | |||||||||||
| Journal: | Postepy Hig Med Dosw (Online). 2014 Jan 22;68:42-7. | ||||||||||
| Title: | [Role of Th17 lymphocytes in pathogenesis of colorectal cancer]. | ||||||||||
| Author: | Karczewski, Jacek|Mazur, Malgorzata|Rychlewska-Hanczewska, Anna|Adamski, Zygmunt | ||||||||||
| PMID: | 24491894 | ||||||||||
| 16. | |||||||||||
| Journal: | Oncogene. 2015 Jul;34(27):3493-503. | ||||||||||
| Title: | Th17-type cytokines, IL-6 and TNF-alpha synergistically activate STAT3 and NF-kB to promote colorectal cancer cell growth. | ||||||||||
| Author: | De Simone, V|Franze, E|Ronchetti, G|Colantoni, A|Fantini, M C|Di Fusco, D|Sica, G S|Sileri, P|MacDonald, T T|Pallone, F|Monteleone, G|Stolfi, C | ||||||||||
| PMID: | 25174402 | ||||||||||
| 17. | |||||||||||
| Journal: | Mol Med Rep. 2015 Feb;11(2):1049-56. | ||||||||||
| Title: | Interleukin21 promotes the development of ulcerative colitis and regulates the proliferation and secretion of follicular T helper cells in the colitides microenvironment. | ||||||||||
| Author: | Yu, Jing|He, Songbing|Liu, Pengfei|Hu, You|Wang, Lei|Wang, Xu|Han, Ye|Zhu, Xinguo | ||||||||||
| PMID: | 25371082 | ||||||||||
| 18. | |||||||||||
| Journal: | Oncotarget. 2015 Apr 30;6(12):9908-23. | ||||||||||
| Title: | Interleukin-21 sustains inflammatory signals that contribute to sporadic colon tumorigenesis. | ||||||||||
| Author: | De Simone, Veronica|Ronchetti, Giulia|Franze, Eleonora|Colantoni, Alfredo|Ortenzi, Angela|Fantini, Massimo C|Rizzo, Angelamaria|Sica, Giuseppe S|Sileri, Pierpaolo|Rossi, Piero|MacDonald, Thomas T|Pallone, Francesco|Monteleone, Giovanni|Stolfi, Carmine | ||||||||||
| PMID: | 25839161 | ||||||||||
| 19. | |||||||||||
| Journal: | Gut. 2016 Sep;65(9):1470-81. | ||||||||||
| Title: | Novel evidence for an oncogenic role of microRNA-21 in colitis-associated colorectal cancer. | ||||||||||
| Author: | Shi, Chenzhang|Yang, Yongzhi|Xia, Yang|Okugawa, Yoshinaga|Yang, Jun|Liang, Yong|Chen, Hongqi|Zhang, Peng|Wang, Feng|Han, Huazhong|Wu, Wen|Gao, Renyuan|Gasche, Christoph|Qin, Huanlong|Ma, Yanlei|Goel, Ajay | ||||||||||
| PMID: | 25994220 | ||||||||||
| 20. | |||||||||||
| Journal: | Cancer Immunol Immunother. 2016 Jan;65(1):13-24. | ||||||||||
| Title: | Deficiency of IL-17A, but not the prototypical Th17 transcription factor RORgammat, decreases murine spontaneous intestinal tumorigenesis. | ||||||||||
| Author: | Shapiro, Mia|Nandi, Bisweswar|Pai, Christine|Samur, Mehmet K|Pelluru, Dheeraj|Fulciniti, Mariateresa|Prabhala, Rao H|Munshi, Nikhil C|Gold, Jason S | ||||||||||
| PMID: | 26559812 | ||||||||||
| 21. | |||||||||||
| Journal: | Oncoimmunology. 2016 Dec 7;6(1):e1261776. | ||||||||||
| Title: | Deficiency of the immunostimulatory cytokine IL-21 promotes intestinal neoplasia via dysregulation of the Th1/Th17 axis. | ||||||||||
| Author: | Shapiro, Mia|Nandi, Bisweswar|Gonzalez, Gabriel|Prabhala, Rao H|Mashimo, Hiroshi|Huang, Qin|Frank, Natasha Y|Munshi, Nikhil C|Gold, Jason S | ||||||||||
| PMID: | 28197386 | ||||||||||
| 22. | |||||||||||
| Journal: | Int J Nanomedicine. 2017 Apr 13;12:3095-3107. | ||||||||||
| Title: | Chitosan nanoparticle-based delivery of fused NKG2D-IL-21 gene suppresses colon cancer growth in mice. | ||||||||||
| Author: | Tan, Lunmei|Han, Sen|Ding, Shizhen|Xiao, Weiming|Ding, Yanbing|Qian, Li|Wang, Chenming|Gong, Weijuan | ||||||||||
| PMID: | 28450784 | ||||||||||
| 23. | |||||||||||
| Journal: | Cancer Prev Res (Phila). 2017 Jul;10(7):398-409. | ||||||||||
| Title: | Fusobacterium Nucleatum Subspecies Animalis Influences Proinflammatory Cytokine Expression and Monocyte Activation in Human Colorectal Tumors. | ||||||||||
| Author: | Ye, Xiangcang|Wang, Rui|Bhattacharya, Rajat|Boulbes, Delphine R|Fan, Fan|Xia, Ling|Adoni, Harish|Ajami, Nadim J|Wong, Matthew C|Smith, Daniel P|Petrosino, Joseph F|Venable, Susan|Qiao, Wei|Baladandayuthapani, Veera|Maru, Dipen|Ellis, Lee M | ||||||||||
| PMID: | 28483840 | ||||||||||
| 24. | |||||||||||
| Journal: | Clin Immunol. 2017 Oct;183:266-272. | ||||||||||
| Title: | Increased expression of interleukin-21 along colorectal adenoma-carcinoma sequence and its predicating significance in patients with sporadic colorectal cancer. | ||||||||||
| Author: | Cui, Guanglin|Yuan, Aping|Zhu, Li|Florholmen, Jon|Goll, Rasmus | ||||||||||
| PMID: | 28887120 | ||||||||||
| 25. | |||||||||||
| Journal: | Cytokine. 2018 Jul;107:35-42. | ||||||||||
| Title: | Th17 cytokine profiling of colorectal cancer patients with or without enterovirus 71 antigen expression. | ||||||||||
| Author: | Li, Yazhen|Qiu, Qiancheng|Fan, Zhiqiang|He, Ping|Chen, Huanzhu|Jiao, Xiaoyang | ||||||||||
| PMID: | 29175261 | ||||||||||
| 26. | |||||||||||
| Journal: | Adv Clin Exp Med. 2018 May;27(5):583-589. | ||||||||||
| Title: | Interleukin 21 treatment in a murine model as a novel potential cytokine immunotherapy for colon cancer. | ||||||||||
| Author: | Chen, Chen|Liu, Xiaoning|Ren, Yi | ||||||||||
| PMID: | 29616746 | ||||||||||
| 27. | |||||||||||
| Journal: | Cytotechnology. 2018 May 25. pii: 10.1007/s10616-018-0228-2. | ||||||||||
| Title: | Neutralizing FGF4 protein in conditioned medium of IL-21-silenced HCT116 cells restores the migratory activity of the colorectal cancer cells. | ||||||||||
| Author: | Abdalkareem, Eshtiyag Abdalla|Ong, Ching Yi|Lim, Boon Huat|Khoo, Boon Yin | ||||||||||
| PMID: | 29802489 | ||||||||||
| 28. | |||||||||||
| Journal: | Exp Cell Res. 2018 Nov 1;372(1):35-42. | ||||||||||
| Title: | Follicular helper T cells promote the effector functions of CD8(+) T cells via the provision of IL-21, which is downregulated due to PD-1/PD-L1-mediated suppression in colorectal cancer. | ||||||||||
| Author: | Shi, Weiwei|Dong, Lin|Sun, Qiong|Ding, Hong|Meng, Jing|Dai, Guanghai | ||||||||||
| PMID: | 30205088 | ||||||||||