Primary Site >> Colorectal Cancer

Gene >> IL13

Journal: J Leukoc Biol. 1996 May;59(5):728-32.
Title: IL-13 restores an in vitro specific cytolytic response of spleen cells from tumor-bearing rats.
Author: Reisser, D|Pinard, D|Jeannin, J F
PMID: 8656059
Journal: J Immunol. 1996 Apr 15;156(8):2972-8.
Title: IL-13 induces phosphorylation and activation of JAK2 Janus kinase in human colon carcinoma cell lines: similarities between IL-4 and IL-13 signaling.
Author: Murata, T|Noguchi, P D|Puri, R K
PMID: 8609418
Journal: J Biol Chem. 1999 Jun 11;274(24):17193-201.
Title: Cytokine-induced apoptosis in epithelial HT-29 cells is independent of nitric oxide formation. Evidence for an interleukin-13-driven phosphatidylinositol 3-kinase-dependent survival mechanism.
Author: Wright, K|Kolios, G|Westwick, J|Ward, S G
PMID: 10358077
Journal: Endocrinology. 1999 Oct;140(10):4573-84.
Title: Induction of 3beta-hydroxysteroid dehydrogenase/isomerase type 1 expression by interleukin-4 in human normal prostate epithelial cells, immortalized keratinocytes, colon, and cervix cancer cell lines.
Author: Gingras, S|Simard, J
PMID: 10499513
Journal: J Biol Chem. 2000 Jan 14;275(2):992-8.
Title: Distinct classes of phosphatidylinositol 3'-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells.
Author: Petiot, A|Ogier-Denis, E|Blommaart, E F|Meijer, A J|Codogno, P
PMID: 10625637
Journal: Br J Cancer. 2000 May;82(10):1717-23.
Title: Regulatory effect of interleukin-4 and interleukin-13 on colon cancer cell adhesion.
Author: Kanai, T|Watanabe, M|Hayashi, A|Nakazawa, A|Yajima, T|Okazawa, A|Yamazaki, M|Ishii, H|Hibi, T
PMID: 10817509
Journal: Mol Cell Endocrinol. 2001 Jan 22;171(1-2):25-40.
Title: Crucial role of cytokines in sex steroid formation in normal and tumoral tissues.
Author: Simard, J|Gingras, S
PMID: 11165008
Journal: Immunol Cell Biol. 2003 Aug;81(4):275-82.
Title: mRNA of MUC2 is stimulated by IL-4, IL-13 or TNF-alpha through a mitogen-activated protein kinase pathway in human colon cancer cells.
Author: Iwashita, Jun|Sato, Yukita|Sugaya, Hiroko|Takahashi, Nagatomo|Sasaki, Hiroshi|Abe, Tatsuya
PMID: 12848848
Journal: J Biol Chem. 2004 Apr 30;279(18):18384-91.
Title: Ceramide-mediated macroautophagy involves inhibition of protein kinase B and up-regulation of beclin 1.
Author: Scarlatti, Francesca|Bauvy, Chantal|Ventruti, Annamaria|Sala, Giusy|Cluzeaud, Francoise|Vandewalle, Alain|Ghidoni, Riccardo|Codogno, Patrice
PMID: 14970205
Journal: Int J Cancer. 2005 Mar 10;114(1):80-7.
Title: Unmasking immunosurveillance against a syngeneic colon cancer by elimination of CD4+ NKT regulatory cells and IL-13.
Author: Park, Jong Myun|Terabe, Masaki|van den Broeke, Leon T|Donaldson, Debra D|Berzofsky, Jay A
PMID: 15523692
Journal: Int Immunopharmacol. 2006 Jul;6(7):1176-80.
Title: Reverse of NK cytolysis resistance of type II cytokine predominant-human tumor cells.
Author: Zhang, Jian|Sun, Rui|Liu, Jie|Wang, Lei|Tian, Zhigang
PMID: 16714222
Journal: Cancer Epidemiol Biomarkers Prev. 2006 Jun;15(6):1126-31.
Title: Inflammation-related gene polymorphisms and colorectal adenoma.
Author: Gunter, Marc J|Canzian, Federico|Landi, Stefano|Chanock, Stephen J|Sinha, Rashmi|Rothman, Nathaniel
PMID: 16775170
Journal: Cytokine. 2006 Aug;35(3-4):171-9.
Title: Changes in hepatic immunoregulatory cytokines in patients with metastatic colorectal carcinoma: implications for hepatic anti-tumour immunity.
Author: Kelly, Anna M|Golden-Mason, Lucy|Traynor, Oscar|Geoghegan, Justin|McEntee, Gerry|Hegarty, John E|O'Farrelly, Cliona
PMID: 16971136
Journal: J Immunother. 2007 Oct;30(7):762-72.
Title: Vaccination of metastatic colorectal cancer patients with matured dendritic cells loaded with multiple major histocompatibility complex class I peptides.
Author: Kavanagh, Brian|Ko, Andrew|Venook, Alan|Margolin, Kim|Zeh, Herbert|Lotze, Michael|Schillinger, Brian|Liu, Weihong|Lu, Ying|Mitsky, Peggie|Schilling, Marta|Bercovici, Nadege|Loudovaris, Maureen|Guillermo, Roy|Lee, Sun Min|Bender, James|Mills, Bonnie|Fong,
PMID: 17893568
Journal: Clin Cancer Res. 2007 Oct 1;13(19):5719-28.
Title: Eotaxin-2 and colorectal cancer: a potential target for immune therapy.
Author: Cheadle, Eleanor J|Riyad, Kallingal|Subar, Daren|Rothwell, Dominic G|Ashton, Garry|Batha, Hayley|Sherlock, David J|Hawkins, Robert E|Gilham, David E
PMID: 17908961
Journal: Gastroenterology. 2008 Sep;135(3):889-98, 898.e1-3.
Title: Activation-induced cytidine deaminase links between inflammation and the development of colitis-associated colorectal cancers.
Author: Endo, Yoko|Marusawa, Hiroyuki|Kou, Tadayuki|Nakase, Hiroshi|Fujii, Shigehiko|Fujimori, Takahiro|Kinoshita, Kazuo|Honjo, Tasuku|Chiba, Tsutomu
PMID: 18691581
Journal: Tumour Biol. 2009;30(4):185-99.
Title: 15-lipoxygenase-1 in colorectal cancer: a review.
Author: Bhattacharya, S|Mathew, G|Jayne, D G|Pelengaris, S|Khan, M
PMID: 19752603
Journal: J Immunol. 2009 Jun 15;182(12):7548-57.
Title: Altered expression of 15-hydroxyprostaglandin dehydrogenase in tumor-infiltrated CD11b myeloid cells: a mechanism for immune evasion in cancer.
Author: Eruslanov, Evgeniy|Kaliberov, Sergei|Daurkin, Irina|Kaliberova, Lyudmila|Buchsbaum, Donald|Vieweg, Johannes|Kusmartsev, Sergei
PMID: 19494278
Journal: Int J Cancer. 2010 Apr 1;126(7):1666-74.
Title: Blockade of TGF-beta enhances tumor vaccine efficacy mediated by CD8(+) T cells.
Author: Takaku, Shun|Terabe, Masaki|Ambrosino, Elena|Peng, Judy|Lonning, Scott|McPherson, John M|Berzofsky, Jay A
PMID: 19830696
Journal: Inflamm Bowel Dis. 2010 May;16(5):753-64.
Title: Elevated IL-13Ralpha2 in intestinal epithelial cells from ulcerative colitis or colorectal cancer initiates MAPK pathway.
Author: Mandal, Debasmita|Levine, Alan D
PMID: 20014020
Journal: Carcinogenesis. 2010 Jun;31(6):1010-7.
Title: Epithelial interleukin-4 receptor expression promotes colon tumor growth.
Author: Koller, Felicitas L|Hwang, Daniel G|Dozier, E A|Fingleton, Barbara
PMID: 20176658
Journal: J Immunol. 2010 Sep 15;185(6):3750-8.
Title: Netrin-1 regulates Th1/Th2/Th17 cytokine production and inflammation through UNC5B receptor and protects kidney against ischemia-reperfusion injury.
Author: Tadagavadi, Raghu Kempegowda|Wang, Weiwei|Ramesh, Ganesan
PMID: 20693423
Journal: Cancer Res. 2011 Feb 15;71(4):1263-71.
Title: Clinical impact of different classes of infiltrating T cytotoxic and helper cells (Th1, th2, treg, th17) in patients with colorectal cancer.
Author: Tosolini, Marie|Kirilovsky, Amos|Mlecnik, Bernhard|Fredriksen, Tessa|Mauger, Stephanie|Bindea, Gabriela|Berger, Anne|Bruneval, Patrick|Fridman, Wolf-Herman|Pages, Franck|Galon, Jerome
PMID: 21303976
Journal: Pol Przegl Chir. 2011 Jan;83(1):27-31.
Title: Association of -1112 c/t promoter region polymorphism of the interleukin 13 gene with occurrence of colorectal cancer.
Author: Walczak, Anna|Przybylowska, Karolina|Trzcinski, Radzislaw|Sygut, Andrzej|Dziki, Lukasz|Dziki, Adam|Majsterek, Ireneusz
PMID: 22166239
Journal: Carcinogenesis. 2011 Sep;32(9):1333-9.
Title: COX-2 inhibition alters the phenotype of tumor-associated macrophages from M2 to M1 in ApcMin/+ mouse polyps.
Author: Nakanishi, Yuki|Nakatsuji, Masato|Seno, Hiroshi|Ishizu, Shoko|Akitake-Kawano, Reiko|Kanda, Keitaro|Ueo, Taro|Komekado, Hideyuki|Kawada, Mayumi|Minami, Manabu|Chiba, Tsutomu
PMID: 21730361
Journal: Tumour Biol. 2011 Oct;32(5):965-76.
Title: Functional gene expression profile underlying methotrexate-induced senescence in human colon cancer cells.
Author: Dabrowska, Magdalena|Skoneczny, Marek|Rode, Wojciech
PMID: 21678067
Journal: Mol Cancer Ther. 2011 Jul;10(7):1149-60.
Title: Silencing IL-13Ralpha2 promotes glioblastoma cell death via endogenous signaling.
Author: Hsi, Linda C|Kundu, Suman|Palomo, Juan|Xu, Bo|Ficco, Ryan|Vogelbaum, Michael A|Cathcart, Martha K
PMID: 21596889
Journal: J Nutr Biochem. 2011 Dec;22(12):1160-71.
Title: Suppression of intestinal inflammation and inflammation-driven colon cancer in mice by dietary sphingomyelin: importance of peroxisome proliferator-activated receptor gamma expression.
Author: Mazzei, Joseph C|Zhou, Hui|Brayfield, Bradley P|Hontecillas, Raquel|Bassaganya-Riera, Josep|Schmelz, Eva M
PMID: 21295961
Journal: Int J Cancer. 2011 Jun 15;128(12):2923-32.
Title: Tumor-reactive CD4+ CD8alphabeta+ CD103+ alphabetaT cells: a prevalent tumor-reactive T-cell subset in metastatic colorectal cancers.
Author: Sarrabayrouse, Guillaume|Corvaisier, Murielle|Ouisse, Laure-Helene|Bossard, Celine|Le Mevel, Bernard|Potiron, Lucien|Meurette, Guillaume|Gervois, Nadine|Jotereau, Francine
PMID: 20824715
Journal: Pharmacogenomics J. 2011 Dec;11(6):437-43.
Title: A large-scale candidate gene approach identifies SNPs in SOD2 and IL13 as predictive markers of response to preoperative chemoradiation in rectal cancer.
Author: Ho-Pun-Cheung, A|Assenat, E|Bascoul-Mollevi, C|Bibeau, F|Boissiere-Michot, F|Thezenas, S|Cellier, D|Azria, D|Rouanet, P|Senesse, P|Ychou, M|Lopez-Crapez, E
PMID: 20644561
Journal: Scand J Immunol. 2012 Jan;75(1):16-26.
Title: Role of natural killer T cells in the mouse colitis-associated colon cancer model.
Author: Yoshioka, K|Ueno, Y|Tanaka, S|Nagai, K|Onitake, T|Hanaoka, R|Watanabe, H|Chayama, K
PMID: 21815907
Journal: Am J Physiol Gastrointest Liver Physiol. 2012 Nov 15;303(10):G1087-95.
Title: Linking tumor-associated macrophages, inflammation, and intestinal tumorigenesis: role of MCP-1.
Author: McClellan, Jamie L|Davis, J Mark|Steiner, Jennifer L|Enos, Reilly T|Jung, Seung H|Carson, James A|Pena, Maria M|Carnevale, Kevin A|Berger, Franklin G|Murphy, E Angela
PMID: 23019193
Journal: DNA Cell Biol. 2012 Aug;31(8):1431-8.
Title: The lL-8 and IL-13 gene polymorphisms in inflammatory bowel disease and colorectal cancer.
Author: Walczak, Anna|Przybylowska, Karolina|Dziki, Lukasz|Sygut, Andrzej|Chojnacki, Cezary|Chojnacki, Jan|Dziki, Adam|Majsterek, Ireneusz
PMID: 22741617
Journal: Cancer Res. 2012 Jun 1;72(11):2780-90.
Title: High expression of IL-13 receptor alpha2 in colorectal cancer is associated with invasion, liver metastasis, and poor prognosis.
Author: Barderas, Rodrigo|Bartolome, Ruben A|Fernandez-Acenero, Maria Jesus|Torres, Sofia|Casal, J Ignacio
PMID: 22505647
Journal: J Clin Endocrinol Metab. 2012 May;97(5):E845-51.
Title: Effect of type 2 diabetes predisposing genetic variants on colorectal cancer risk.
Author: Sainz, Juan|Rudolph, Anja|Hoffmeister, Michael|Frank, Bernd|Brenner, Hermann|Chang-Claude, Jenny|Hemminki, Kari|Forsti, Asta
PMID: 22419714
Journal: Biochem Pharmacol. 2012 May 1;83(9):1195-207.
Title: Antiproliferative mechanisms of action of the flavin dehydrogenase inhibitors diphenylene iodonium and di-2-thienyliodonium based on molecular profiling of the NCI-60 human tumor cell panel.
Author: Doroshow, James H|Juhasz, Agnes|Ge, Yun|Holbeck, Susan|Lu, Jiamo|Antony, Smitha|Wu, Yongzhong|Jiang, Guojian|Roy, Krishnendu
PMID: 22305747
Journal: Cell Signal. 2012 Mar;24(3):718-25.
Title: Stat6 activity-related Th2 cytokine profile and tumor growth advantage of human colorectal cancer cells in vitro and in vivo.
Author: Li, Ben Hui|Xu, Shuang Bing|Li, Feng|Zou, Xiao Guang|Saimaiti, Abudukeyoumu|Simayi, Dilixia|Wang, Ying Hong|Zhang, Yan|Yuan, Jia|Zhang, Wen Jie
PMID: 22108090
Journal: Int J Colorectal Dis. 2012 Oct;27(10):1369-76. Epub 2012 Mar 24.
Title: Expression of interleukin-4 and interleukin-13 and their receptors in colorectal cancer.
Author: Formentini, Andrea|Braun, Philipp|Fricke, Harald|Link, Karl-Heinrich|Henne-Bruns, Doris|Kornmann, Marko
PMID: 22441356
Journal: Biomed Rep. 2013 Sep;1(5):687-690.
Title: Interleukin-13 and its receptors in colorectal cancer (Review).
Author: Zhou, Ru|Qian, Shiguang|Gu, Xiaodong|Chen, Zongyou|Xiang, Jianbin
PMID: 24649010
Journal: Mol Ther. 2014 Jan;22(1):18-27.
Title: Tissues in different anatomical sites can sculpt and vary the tumor microenvironment to affect responses to therapy.
Author: Devaud, Christel|Westwood, Jennifer A|John, Liza B|Flynn, Jacqueline K|Paquet-Fifield, Sophie|Duong, Connie P M|Yong, Carmen S M|Pegram, Hollie J|Stacker, Steven A|Achen, Marc G|Stewart, Trina J|Snyder, Linda A|Teng, Michele W L|Smyth, Mark J|Darcy, Phill
PMID: 24048441
Journal: World J Gastroenterol. 2014 Feb 7;20(5):1332-9.
Title: Evaluation of specific fecal protein biochips for the diagnosis of colorectal cancer.
Author: Wang, Hui-Peng|Wang, Yang-Yun|Pan, Jie|Cen, Rong|Cai, Yuan-Kun
PMID: 24574808
Journal: Eur J Clin Pharmacol. 2015 May;71(5):529-39.
Title: Germ line polymorphisms as predictive markers for pre-surgical radiochemotherapy in locally advanced rectal cancer: a 5-year literature update and critical review.
Author: Pezzolo, Elisa|Modena, Yasmina|Corso, Barbara|Giusti, Pietro|Gusella, Milena
PMID: 25740678
Journal: Cancer Biol Ther. 2015;16(5):671-7.
Title: Laparoscopic surgery for colorectal cancer is not associated with an increase in the circulating levels of several inflammation-related factors.
Author: Crucitti, Antonio|Corbi, Maddalena|Tomaiuolo, Pasquina Mc|Fanali, Caterina|Mazzari, Andrea|Lucchetti, Donatella|Migaldi, Mario|Sgambato, Alessandro
PMID: 25875151
Journal: Cancer Res. 2015 Jun 15;75(12):2434-44.
Title: IL13 Receptor alpha2 Signaling Requires a Scaffold Protein, FAM120A, to Activate the FAK and PI3K Pathways in Colon Cancer Metastasis.
Author: Bartolome, Ruben A|Garcia-Palmero, Irene|Torres, Sofia|Lopez-Lucendo, Maria|Balyasnikova, Irina V|Casal, J Ignacio
PMID: 25896327
Journal: Anticancer Res. 2015 Jul;35(7):3761-6.
Title: Systematic Review of Candidate Single-nucleotide Polymorphisms as Biomarkers for Responsiveness to Neoadjuvant Chemoradiation for Rectal Cancer.
Author: Maring, Elizabeth D|Tawadros, Patrick S|Steer, Clifford J|Lee, Janet T
PMID: 26124319
Journal: Oncoimmunology. 2015 Mar 19;4(6):e1008355.
Title: Tumor-infiltrating plasmacytoid dendritic cells promote immunosuppression by Tr1 cells in human liver tumors.
Author: Pedroza-Gonzalez, Alexander|Zhou, Guoying|Vargas-Mendez, Ernesto|Boor, Patrick Pc|Mancham, Shanta|Verhoef, Cornelis|Polak, Wojciech G|Grunhagen, Dirk|Pan, Qiuwei|Janssen, Harry LA|Garcia-Romo, Gina S|Biermann, Katharina|Tjwa, Eric Ttl|IJzermans, Jan Nm|Kw
PMID: 26155417
Journal: Am J Transl Res. 2016 Feb 15;8(2):1064-72. eCollection 2016.
Title: IL-13 induces the expression of 11betaHSD2 in IL-13Ralpha2 dependent manner and promotes the malignancy of colorectal cancer.
Author: Jiang, Li|Cheng, Qi|Zhang, Binhao|Zhang, Mingzhi
PMID: 27158392
Journal: Oncol Lett. 2016 Dec;12(6):4929-4936.
Title: Effect of IL-17 in the development of colon cancer in mice.
Author: Yang, Lijuan|Liu, Hao|Zhang, Lili|Hu, Jie|Chen, Haixia|Wang, Lei|Yin, Xiaolin|Li, Quanhai|Qi, Yixin
PMID: 28101230
Journal: Oncotarget. 2016 Nov 15;7(46):75685-75697.
Title: Differential effects of peptidoglycan on colorectal tumors and intestinal tissue post-pelvic radiotherapy.
Author: Li, Gen|Wu, Anqing|Qi, Dandan|Cui, Fengmei|Zeng, Yanan|Xie, Fang|Wu, Hongya|Gu, Yongping|Chen, Qiu|Zhang, Xueguang
PMID: 27708223
Journal: Oncotarget. 2016 Sep 20;7(38):61183-61198.
Title: IL-13/STAT6 signaling plays a critical role in the epithelial-mesenchymal transition of colorectal cancer cells.
Author: Cao, Hui|Zhang, Jing|Liu, Hong|Wan, Ledong|Zhang, Honghe|Huang, Qiong|Xu, Enping|Lai, Maode
PMID: 27533463
Journal: Int J Mol Med. 2016 May;37(5):1221-8.
Title: Erythronium japonicum attenuates histopathological lung abnormalities in a mouse model of ovalbumin-induced asthma.
Author: Seo, Ji-Hye|Bang, Mi-Ae|Kim, Gyeyeop|Cho, Seung Sik|Park, Dae-Hun
PMID: 27035741
Journal: Immunol Invest. 2017 Apr;46(3):221-238.
Title: Immunomodulating and Immunoresistance Properties of Cancer-Initiating Cells: Implications for the Clinical Success of Immunotherapy.
Author: Maccalli, Cristina|Parmiani, Giorgio|Ferrone, Soldano
PMID: 28287848
Journal: Oncotarget. 2017 Jun 13;8(24):38113-38135.
Title: Interleukin-4 and interleukin-13 increase NADPH oxidase 1-related proliferation of human colon cancer cells.
Author: Liu, Han|Antony, Smitha|Roy, Krishnendu|Juhasz, Agnes|Wu, Yongzhong|Lu, Jiamo|Meitzler, Jennifer L|Jiang, Guojian|Polley, Eric|Doroshow, James H
PMID: 28498822
Journal: Oncotarget. 2017 Jul 18;8(29):47379-47388.
Title: Dietary factors and microRNA-binding site polymorphisms in the IL13 gene: risk and prognosis analysis of colorectal cancer.
Author: Yu, Yanming|Zhou, Junde|Gong, Chen|Long, Zhiping|Tian, Jingshen|Zhu, Lin|Li, Jing|Yu, Hongyuan|Wang, Fan|Zhao, Yashuang
PMID: 28537887
Journal: Inflamm Bowel Dis. 2017 Sep;23(9):1524-1534.
Title: CD103+ Dendritic Cell Function Is Altered in the Colons of Patients with Ulcerative Colitis.
Author: Matsuno, Hiroshi|Kayama, Hisako|Nishimura, Junichi|Sekido, Yuki|Osawa, Hideki|Barman, Soumik|Ogino, Takayuki|Takahashi, Hidekazu|Haraguchi, Naotsugu|Hata, Taishi|Matsuda, Chu|Yamamoto, Hirofumi|Uchino, Motoi|Ikeuchi, Hiroki|Doki, Yuichiro|Mori, Masaki|Tak
PMID: 28700533
Journal: Clin Transl Immunology. 2017 Oct 6;6(10):e157.
Title: Suppression of inflammation and tissue damage by a hookworm recombinant protein in experimental colitis.
Author: Ferreira, Ivana B|Pickering, Darren A|Troy, Sally|Croese, John|Loukas, Alex|Navarro, Severine
PMID: 29114386
Journal: Cell Biol Int. 2018 Aug;42(8):985-993.
Title: Propofol prevents IL-13-induced epithelial-mesenchymal transition in human colorectal cancer cells.
Author: Xu, Kejia|Tao, Weimin|Su, Zhe
PMID: 29569786
Journal: Cell Commun Signal. 2018 Apr 24;16(1):17.
Title: Effect of colorectal cancer-derived extracellular vesicles on the immunophenotype and cytokine secretion profile of monocytes and macrophages.
Author: Popena, Ineta|Abols, Arturs|Saulite, Liga|Pleiko, Karlis|Zandberga, Elina|Jekabsons, Kaspars|Endzelins, Edgars|Llorente, Alicia|Line, Aija|Riekstina, Una
PMID: 29690889
Journal: Cytokine. 2018 Oct;110:435-441.
Title: Subsite heterogeneity in the profiles of circulating cytokines in colorectal cancer.
Author: Krzystek-Korpacka, Malgorzata|Zawadzki, Marek|Kapturkiewicz, Bartosz|Lewandowska, Paulina|Bednarz-Misa, Iwona|Gorska, Sabina|Witkiewicz, Wojciech|Gamian, Andrzej
PMID: 29801973
Journal: Clin Chim Acta. 2018 Sep 15;487:101-106.
Title: Association study on IL-4, IL-4Ralpha and IL-13 genetic polymorphisms in Swedish patients with colorectal cancer.
Author: Shamoun, Levar|Skarstedt, Marita|Andersson, Roland E|Wagsater, Dick|Dimberg, Jan
PMID: 30227113