Primary Site >> Colorectal Cancer
Gene >> IL13
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Ref: IL-13 induces phosphorylation and activation of JAK2 Janus kinase in human colon carcinoma cell lines: similarities between IL-4 and IL-13 signaling. PMID: 8609418 Ref: IL-13 restores an in vitro specific cytolytic response of spleen cells from tumor-bearing rats. PMID: 8656059 |
Ref: Cytokine-induced apoptosis in epithelial HT-29 cells is independent of nitric oxide formation. Evidence for an interleukin-13-driven phosphatidylinositol 3-kinase-dependent survival mechanism. PMID: 10358077 Ref: Induction of 3beta-hydroxysteroid dehydrogenase/isomerase type 1 expression by interleukin-4 in human normal prostate epithelial cells, immortalized keratinocytes, colon, and cervix cancer cell lines. PMID: 10499513 |
Ref: Distinct classes of phosphatidylinositol 3'-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells. PMID: 10625637 Ref: Regulatory effect of interleukin-4 and interleukin-13 on colon cancer cell adhesion. PMID: 10817509 |
Ref: Crucial role of cytokines in sex steroid formation in normal and tumoral tissues. PMID: 11165008 |
Ref: mRNA of MUC2 is stimulated by IL-4, IL-13 or TNF-alpha through a mitogen-activated protein kinase pathway in human colon cancer cells. PMID: 12848848 |
Ref: Ceramide-mediated macroautophagy involves inhibition of protein kinase B and up-regulation of beclin 1. PMID: 14970205 |
Ref: Unmasking immunosurveillance against a syngeneic colon cancer by elimination of CD4+ NKT regulatory cells and IL-13. PMID: 15523692 |
Ref: Reverse of NK cytolysis resistance of type II cytokine predominant-human tumor cells. PMID: 16714222 Ref: Inflammation-related gene polymorphisms and colorectal adenoma. PMID: 16775170 Ref: Changes in hepatic immunoregulatory cytokines in patients with metastatic colorectal carcinoma: implications for hepatic anti-tumour immunity. PMID: 16971136 |
Ref: Vaccination of metastatic colorectal cancer patients with matured dendritic cells loaded with multiple major histocompatibility complex class I peptides. PMID: 17893568 Ref: Eotaxin-2 and colorectal cancer: a potential target for immune therapy. PMID: 17908961 |
Ref: Activation-induced cytidine deaminase links between inflammation and the development of colitis-associated colorectal cancers. PMID: 18691581 |
Ref: Altered expression of 15-hydroxyprostaglandin dehydrogenase in tumor-infiltrated CD11b myeloid cells: a mechanism for immune evasion in cancer. PMID: 19494278 Ref: 15-lipoxygenase-1 in colorectal cancer: a review. PMID: 19752603 |
Ref: Blockade of TGF-beta enhances tumor vaccine efficacy mediated by CD8(+) T cells. PMID: 19830696 Ref: Elevated IL-13Ralpha2 in intestinal epithelial cells from ulcerative colitis or colorectal cancer initiates MAPK pathway. PMID: 20014020 Ref: Epithelial interleukin-4 receptor expression promotes colon tumor growth. PMID: 20176658 Ref: Netrin-1 regulates Th1/Th2/Th17 cytokine production and inflammation through UNC5B receptor and protects kidney against ischemia-reperfusion injury. PMID: 20693423 |
Ref: A large-scale candidate gene approach identifies SNPs in SOD2 and IL13 as predictive markers of response to preoperative chemoradiation in rectal cancer. PMID: 20644561 Ref: Tumor-reactive CD4+ CD8alphabeta+ CD103+ alphabetaT cells: a prevalent tumor-reactive T-cell subset in metastatic colorectal cancers. PMID: 20824715 Ref: Suppression of intestinal inflammation and inflammation-driven colon cancer in mice by dietary sphingomyelin: importance of peroxisome proliferator-activated receptor gamma expression. PMID: 21295961 Ref: Clinical impact of different classes of infiltrating T cytotoxic and helper cells (Th1, th2, treg, th17) in patients with colorectal cancer. PMID: 21303976 Ref: Silencing IL-13Ralpha2 promotes glioblastoma cell death via endogenous signaling. PMID: 21596889 Ref: Functional gene expression profile underlying methotrexate-induced senescence in human colon cancer cells. PMID: 21678067 Ref: COX-2 inhibition alters the phenotype of tumor-associated macrophages from M2 to M1 in ApcMin/+ mouse polyps. PMID: 21730361 Ref: Association of -1112 c/t promoter region polymorphism of the interleukin 13 gene with occurrence of colorectal cancer. PMID: 22166239 |
Ref: Role of natural killer T cells in the mouse colitis-associated colon cancer model. PMID: 21815907 Ref: Stat6 activity-related Th2 cytokine profile and tumor growth advantage of human colorectal cancer cells in vitro and in vivo. PMID: 22108090 Ref: Antiproliferative mechanisms of action of the flavin dehydrogenase inhibitors diphenylene iodonium and di-2-thienyliodonium based on molecular profiling of the NCI-60 human tumor cell panel. PMID: 22305747 Ref: Effect of type 2 diabetes predisposing genetic variants on colorectal cancer risk. PMID: 22419714 Ref: Expression of interleukin-4 and interleukin-13 and their receptors in colorectal cancer. PMID: 22441356 Ref: High expression of IL-13 receptor alpha2 in colorectal cancer is associated with invasion, liver metastasis, and poor prognosis. PMID: 22505647 Ref: The lL-8 and IL-13 gene polymorphisms in inflammatory bowel disease and colorectal cancer. PMID: 22741617 Ref: Linking tumor-associated macrophages, inflammation, and intestinal tumorigenesis: role of MCP-1. PMID: 23019193 |
Ref: Interleukin-13 and its receptors in colorectal cancer (Review). PMID: 24649010 |
Ref: Tissues in different anatomical sites can sculpt and vary the tumor microenvironment to affect responses to therapy. PMID: 24048441 Ref: Evaluation of specific fecal protein biochips for the diagnosis of colorectal cancer. PMID: 24574808 |
Ref: Germ line polymorphisms as predictive markers for pre-surgical radiochemotherapy in locally advanced rectal cancer: a 5-year literature update and critical review. PMID: 25740678 Ref: Laparoscopic surgery for colorectal cancer is not associated with an increase in the circulating levels of several inflammation-related factors. PMID: 25875151 Ref: IL13 Receptor alpha2 Signaling Requires a Scaffold Protein, FAM120A, to Activate the FAK and PI3K Pathways in Colon Cancer Metastasis. PMID: 25896327 Ref: Systematic Review of Candidate Single-nucleotide Polymorphisms as Biomarkers for Responsiveness to Neoadjuvant Chemoradiation for Rectal Cancer. PMID: 26124319 Ref: Tumor-infiltrating plasmacytoid dendritic cells promote immunosuppression by Tr1 cells in human liver tumors. PMID: 26155417 |
Ref: Erythronium japonicum attenuates histopathological lung abnormalities in a mouse model of ovalbumin-induced asthma. PMID: 27035741 Ref: IL-13 induces the expression of 11betaHSD2 in IL-13Ralpha2 dependent manner and promotes the malignancy of colorectal cancer. PMID: 27158392 Ref: IL-13/STAT6 signaling plays a critical role in the epithelial-mesenchymal transition of colorectal cancer cells. PMID: 27533463 Ref: Differential effects of peptidoglycan on colorectal tumors and intestinal tissue post-pelvic radiotherapy. PMID: 27708223 Ref: Effect of IL-17 in the development of colon cancer in mice. PMID: 28101230 |
Ref: Immunomodulating and Immunoresistance Properties of Cancer-Initiating Cells: Implications for the Clinical Success of Immunotherapy. PMID: 28287848 Ref: Interleukin-4 and interleukin-13 increase NADPH oxidase 1-related proliferation of human colon cancer cells. PMID: 28498822 Ref: Dietary factors and microRNA-binding site polymorphisms in the IL13 gene: risk and prognosis analysis of colorectal cancer. PMID: 28537887 Ref: CD103+ Dendritic Cell Function Is Altered in the Colons of Patients with Ulcerative Colitis. PMID: 28700533 Ref: Suppression of inflammation and tissue damage by a hookworm recombinant protein in experimental colitis. PMID: 29114386 |
Ref: Propofol prevents IL-13-induced epithelial-mesenchymal transition in human colorectal cancer cells. PMID: 29569786 Ref: Effect of colorectal cancer-derived extracellular vesicles on the immunophenotype and cytokine secretion profile of monocytes and macrophages. PMID: 29690889 Ref: Subsite heterogeneity in the profiles of circulating cytokines in colorectal cancer. PMID: 29801973 Ref: Association study on IL-4, IL-4Ralpha and IL-13 genetic polymorphisms in Swedish patients with colorectal cancer. PMID: 30227113 |