Primary Site >> Stomach Cancer

Gene >> IL11

Journal: Gastroenterology. 2005 Sep;129(3):1005-18.
Title: Differential regulation of gastric tumor growth by cytokines that signal exclusively through the coreceptor gp130.
Author: Howlett, Meegan|Judd, Louise M|Jenkins, Brendan|La Gruta, Nicole L|Grail, Dianne|Ernst, Matthias|Giraud, Andrew S
PMID: 16143138
Journal: Int J Oncol. 2007 Apr;30(4):825-33.
Title: Expression of interleukin-11 (IL-11) and IL-11 receptor alpha in human gastric carcinoma and IL-11 upregulates the invasive activity of human gastric carcinoma cells.
Author: Nakayama, Toshiyuki|Yoshizaki, Ayumi|Izumida, Seiya|Suehiro, Tomoyuki|Miura, Shiro|Uemura, Takashi|Yakata, Yuichi|Shichijo, Kazuko|Yamashita, Shunichi|Sekin, Ichiro
PMID: 17332920
Journal: J Pathol. 2007 Oct;213(2):140-51.
Title: Augmented gp130-mediated cytokine signalling accompanies human gastric cancer progression.
Author: Jackson, C B|Judd, L M|Menheniott, T R|Kronborg, I|Dow, C|Yeomans, N D|Boussioutas, A|Robb, L|Giraud, A S
PMID: 17724739
Journal: J Clin Invest. 2008 May;118(5):1628-31.
Title: What lurks beneath: IL-11, via Stat3, promotes inflammation-associated gastric tumorigenesis.
Author: Merchant, Juanita L
PMID: 18431518
Journal: J Clin Invest. 2008 May;118(5):1727-38.
Title: STAT3 and STAT1 mediate IL-11-dependent and inflammation-associated gastric tumorigenesis in gp130 receptor mutant mice.
Author: Ernst, Matthias|Najdovska, Meri|Grail, Dianne|Lundgren-May, Therese|Buchert, Michael|Tye, Hazel|Matthews, Vance B|Armes, Jane|Bhathal, Prithi S|Hughes, Norman R|Marcusson, Eric G|Karras, James G|Na, Songqing|Sedgwick, Jonathon D|Hertzog, Paul J|Jenkins, B
PMID: 18431520
Journal: Gastroenterology. 2009 Mar;136(3):967-77.
Title: The interleukin-6 family cytokine interleukin-11 regulates homeostatic epithelial cell turnover and promotes gastric tumor development.
Author: Howlett, Meegan|Giraud, Andrew S|Lescesen, Helen|Jackson, Cameron B|Kalantzis, Anastasia|Van Driel, Ian R|Robb, Lorraine|Van der Hoek, Mark|Ernst, Matthias|Minamoto, Toshinari|Boussioutas, Alex|Oshima, Hiroko|Oshima, Masanobu|Judd, Louise M
PMID: 19121317
Journal: Biochim Biophys Acta. 2009 Nov;1793(11):1623-33.
Title: Cytokine signalling via gp130 in gastric cancer.
Author: Howlett, M|Menheniott, T R|Judd, L M|Giraud, A S
PMID: 19665497
Journal: J Pathol. 2011 Oct;225(2):255-64.
Title: The molecular pathogenesis of STAT3-driven gastric tumourigenesis in mice is independent of IL-17.
Author: Kennedy, Catherine L|Najdovska, Meri|Jones, Gareth W|McLeod, Louise|Hughes, Norman R|Allison, Cody|Ooi, Chia Huey|Tan, Patrick|Ferrero, Richard L|Jones, Simon A|Dev, Anouk|Sievert, William|Bhathal, Prithi S|Jenkins, Brendan J
PMID: 21710691
Journal: Gut. 2012 Oct;61(10):1398-409.
Title: IL-11 is a parietal cell cytokine that induces atrophic gastritis.
Author: Howlett, Meegan|Chalinor, Heather V|Buzzelli, Jon N|Nguyen, Nhung|van Driel, Ian R|Bell, Katrina M|Fox, James G|Dimitriadis, Eva|Menheniott, Trevelyan R|Giraud, Andrew S|Judd, Louise M
PMID: 22180059
Journal: Int J Biol Sci. 2012;8(3):383-93.
Title: Interleukin-11 promotes the progress of gastric carcinoma via abnormally expressed versican.
Author: Zhang, Zhenwei|Zhang, Jianpeng|Miao, Lei|Liu, Ke|Yang, Shengsheng|Pan, Chuanyong|Jiao, Binghua
PMID: 22393310
Journal: J Gastrointestin Liver Dis. 2012 Mar;21(1):23-9.
Title: IL-6 and IL-11 as markers for tumor aggressiveness and prognosis in gastric adenocarcinoma patients without mutations in Gp130 subunits.
Author: Necula, Laura G|Chivu-Economescu, Mihaela|Stanciulescu, Elena L|Bleotu, Coralia|Dima, Simona O|Alexiu, Irina|Dumitru, Adriana|Constantinescu, Gabriel|Popescu, Irinel|Diaconu, Carmen C
PMID: 22457856
Journal: Cytokine. 2012 Aug;59(2):352-7.
Title: IL10, IL11, IL18 are differently expressed in CD14+ TAMs and play different role in regulating the invasion of gastric cancer cells under hypoxia.
Author: Shen, Zhanlong|Seppanen, Hanna|Vainionpaa, Sanna|Ye, Yingjiang|Wang, Shan|Mustonen, Harri|Puolakkainen, Pauli
PMID: 22595646
Journal: PLoS One. 2012;7(10):e48039.
Title: Inflammation and Gli2 suppress gastrin gene expression in a murine model of antral hyperplasia.
Author: Saqui-Salces, Milena|Coves-Datson, Evelyn|Veniaminova, Natalia A|Waghray, Meghna|Syu, Li-Jyun|Dlugosz, Andrzej A|Merchant, Juanita L
PMID: 23110168
Journal: Cancer Cell. 2013 Aug 12;24(2):257-71.
Title: Interleukin-11 is the dominant IL-6 family cytokine during gastrointestinal tumorigenesis and can be targeted therapeutically.
Author: Putoczki, Tracy L|Thiem, Stefan|Loving, Andrea|Busuttil, Rita A|Wilson, Nicholas J|Ziegler, Paul K|Nguyen, Paul M|Preaudet, Adele|Farid, Ryan|Edwards, Kirsten M|Boglev, Yeliz|Luwor, Rodney B|Jarnicki, Andrew|Horst, David|Boussioutas, Alex|Heath, Joan K|Si
PMID: 23948300
Journal: Oncol Rep. 2013 Feb;29(2):791-7.
Title: The novel focal adhesion gene kindlin-2 promotes the invasion of gastric cancer cells mediated by tumor-associated macrophages.
Author: Shen, Zhanlong|Ye, Yingjiang|Kauttu, Tuuli|Seppanen, Hanna|Vainionpaa, Sanna|Wang, Shan|Mustonen, Harri|Puolakkainen, Pauli
PMID: 23151599
Journal: Gut. 2014 Jan;63(1):54-63.
Title: Gastric colonisation with a restricted commensal microbiota replicates the promotion of neoplastic lesions by diverse intestinal microbiota in the Helicobacter pylori INS-GAS mouse model of gastric carcinogenesis.
Author: Lertpiriyapong, Kvin|Whary, Mark T|Muthupalani, Sureshkumar|Lofgren, Jennifer L|Gamazon, Eric R|Feng, Yan|Ge, Zhongming|Wang, Timothy C|Fox, James G
PMID: 23812323
Journal: Mol Med Rep. 2014 Apr;9(4):1371-5.
Title: Interleukin-11 induces the expression of matrix metalloproteinase 13 in gastric cancer SCH cells partly via the PI3K-AKT and JAK-STAT3 pathways.
Author: Yang, Gongli|Ma, Feng|Zhong, Muxiao|Fang, Lin|Peng, Yao|Xin, Xiaoming|Zhong, Jietao|Zhu, Wei|Zhang, Yali
PMID: 24504547
Journal: PLoS One. 2014 May 7;9(5):e95993.
Title: Inhibition of the JAK2/STAT3 pathway reduces gastric cancer growth in vitro and in vivo.
Author: Judd, Louise M|Menheniott, Treve R|Ling, Hui|Jackson, Cameron B|Howlett, Meegan|Kalantzis, Anastasia|Priebe, Waldemar|Giraud, Andrew S
PMID: 24804649
Journal: Oncotarget. 2015 Jan 20;6(2):679-95.
Title: IL-1RT1 signaling antagonizes IL-11 induced STAT3 dependent cardiac and antral stomach tumor development through myeloid cell enrichment.
Author: Buzzelli, Jon N|Pavlic, Dan I|Chalinor, Heather V|O'Connor, Louise|Menheniott, Trevelyan R|Giraud, Andrew S|Judd, Louise M
PMID: 25528766
Journal: BMC Cancer. 2015 May 2;15:343.
Title: MTA2 enhances colony formation and tumor growth of gastric cancer cells through IL-11.
Author: Zhou, Chenfei|Ji, Jun|Cai, Qu|Shi, Min|Chen, Xuehua|Yu, Yingyan|Zhu, Zhenggang|Zhang, Jun
PMID: 25929737
Journal: Mol Med Rep. 2015 Oct;12(4):5601.
Title: [Retraction] Interleukin-11 induces the expression of matrix metalloproteinase 13 in gastric cancer SCH cells partly via the PI3K-AKT and JAK-STAT3 pathways.
Author:
PMID: 26238072
Journal: J Clin Invest. 2016 Apr 1;126(4):1383-400.
Title: Loss of gastrokine-2 drives premalignant gastric inflammation and tumor progression.
Author: Menheniott, Trevelyan R|O'Connor, Louise|Chionh, Yok Teng|Dabritz, Jan|Scurr, Michelle|Rollo, Benjamin N|Ng, Garrett Z|Jacobs, Shelley|Catubig, Angelique|Kurklu, Bayzar|Mercer, Stephen|Minamoto, Toshinari|Ong, David E|Ferrero, Richard L|Fox, James G|Wang,
PMID: 26974160
Journal: Cancer Sci. 2016 Apr;107(4):391-7.
Title: Inflammation in gastric cancer: Interplay of the COX-2/prostaglandin E2 and Toll-like receptor/MyD88 pathways.
Author: Echizen, Kanae|Hirose, Osamu|Maeda, Yusuke|Oshima, Masanobu
PMID: 27079437
Journal: Genet Mol Res. 2016 Apr 25;15(2). pii: gmr7358.
Title: Role of the IL-11/STAT3 signaling pathway in human chronic atrophic gastritis and gastric cancer.
Author: Wang, D Q|Ding, X P|Yin, S|Mao, Y D
PMID: 27173233
Journal: Cytokine. 2017 Apr;92:118-123.
Title: Interleukin-11-driven gastric tumourigenesis is independent of trans-signalling.
Author: Balic, Jesse J|Garbers, Christoph|Rose-John, Stefan|Yu, Liang|Jenkins, Brendan J
PMID: 28160627
Journal: Cancer Sci. 2017 Dec;108(12):2342-2351.
Title: Requisite role of vasohibin-2 in spontaneous gastric cancer formation and accumulation of cancer-associated fibroblasts.
Author: Suzuki, Yasuhiro|Kitahara, Shuji|Suematsu, Takuya|Oshima, Masanobu|Sato, Yasufumi
PMID: 28960674
Journal: Cancer Res Treat. 2018 Apr 20. pii: crt.2018.031.
Title: Cancer-Associated-Fibroblasts Promote the Chemo-Resistance in Gastric Cancer through Secreting IL-11 targeting JAK/STAT3/Bcl2 Pathway.
Author: Ma, Jun|Song, Xiao|Xu, Xiaowu|Mou, Yiping
PMID: 29690750
Journal: Exp Cell Res. 2018 Jul 15;368(2):184-193.
Title: Cancer-associated fibroblasts-stimulated interleukin-11 promotes metastasis of gastric cancer cells mediated by upregulation of MUC1.
Author: Wang, Xiaoxun|Che, Xiaofang|Liu, Chang|Fan, Yibo|Bai, Ming|Hou, Kezuo|Shi, Xiaonan|Zhang, Xiaojie|Liu, Bofang|Zheng, Chunlei|Liu, Yunpeng|Qu, Xiujuan
PMID: 29709516