Primary Site >> Stomach Cancer
Gene >> IL11
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Ref: Differential regulation of gastric tumor growth by cytokines that signal exclusively through the coreceptor gp130. PMID: 16143138 |
Ref: Expression of interleukin-11 (IL-11) and IL-11 receptor alpha in human gastric carcinoma and IL-11 upregulates the invasive activity of human gastric carcinoma cells. PMID: 17332920 Ref: Augmented gp130-mediated cytokine signalling accompanies human gastric cancer progression. PMID: 17724739 |
Ref: What lurks beneath: IL-11, via Stat3, promotes inflammation-associated gastric tumorigenesis. PMID: 18431518 Ref: STAT3 and STAT1 mediate IL-11-dependent and inflammation-associated gastric tumorigenesis in gp130 receptor mutant mice. PMID: 18431520 |
Ref: The interleukin-6 family cytokine interleukin-11 regulates homeostatic epithelial cell turnover and promotes gastric tumor development. PMID: 19121317 Ref: Cytokine signalling via gp130 in gastric cancer. PMID: 19665497 |
Ref: The molecular pathogenesis of STAT3-driven gastric tumourigenesis in mice is independent of IL-17. PMID: 21710691 |
Ref: IL-11 is a parietal cell cytokine that induces atrophic gastritis. PMID: 22180059 Ref: Interleukin-11 promotes the progress of gastric carcinoma via abnormally expressed versican. PMID: 22393310 Ref: IL-6 and IL-11 as markers for tumor aggressiveness and prognosis in gastric adenocarcinoma patients without mutations in Gp130 subunits. PMID: 22457856 Ref: IL10, IL11, IL18 are differently expressed in CD14+ TAMs and play different role in regulating the invasion of gastric cancer cells under hypoxia. PMID: 22595646 Ref: Inflammation and Gli2 suppress gastrin gene expression in a murine model of antral hyperplasia. PMID: 23110168 |
Ref: The novel focal adhesion gene kindlin-2 promotes the invasion of gastric cancer cells mediated by tumor-associated macrophages. PMID: 23151599 Ref: Interleukin-11 is the dominant IL-6 family cytokine during gastrointestinal tumorigenesis and can be targeted therapeutically. PMID: 23948300 |
Ref: Gastric colonisation with a restricted commensal microbiota replicates the promotion of neoplastic lesions by diverse intestinal microbiota in the Helicobacter pylori INS-GAS mouse model of gastric carcinogenesis. PMID: 23812323 Ref: Interleukin-11 induces the expression of matrix metalloproteinase 13 in gastric cancer SCH cells partly via the PI3K-AKT and JAK-STAT3 pathways. PMID: 24504547 Ref: Inhibition of the JAK2/STAT3 pathway reduces gastric cancer growth in vitro and in vivo. PMID: 24804649 |
Ref: IL-1RT1 signaling antagonizes IL-11 induced STAT3 dependent cardiac and antral stomach tumor development through myeloid cell enrichment. PMID: 25528766 Ref: MTA2 enhances colony formation and tumor growth of gastric cancer cells through IL-11. PMID: 25929737 Ref: [Retraction] Interleukin-11 induces the expression of matrix metalloproteinase 13 in gastric cancer SCH cells partly via the PI3K-AKT and JAK-STAT3 pathways. PMID: 26238072 |
Ref: Loss of gastrokine-2 drives premalignant gastric inflammation and tumor progression. PMID: 26974160 Ref: Inflammation in gastric cancer: Interplay of the COX-2/prostaglandin E2 and Toll-like receptor/MyD88 pathways. PMID: 27079437 Ref: Role of the IL-11/STAT3 signaling pathway in human chronic atrophic gastritis and gastric cancer. PMID: 27173233 |
Ref: Interleukin-11-driven gastric tumourigenesis is independent of trans-signalling. PMID: 28160627 Ref: Requisite role of vasohibin-2 in spontaneous gastric cancer formation and accumulation of cancer-associated fibroblasts. PMID: 28960674 |
Ref: Cancer-Associated-Fibroblasts Promote the Chemo-Resistance in Gastric Cancer through Secreting IL-11 targeting JAK/STAT3/Bcl2 Pathway. PMID: 29690750 Ref: Cancer-associated fibroblasts-stimulated interleukin-11 promotes metastasis of gastric cancer cells mediated by upregulation of MUC1. PMID: 29709516 |