Primary Site >> Colorectal Cancer

Gene >> IGFBP4

Journal: Cancer Res. 1991 Jun 1;51(11):2813-9.
Title: Purification of a colon cancer cell growth inhibitor and its identification as an insulin-like growth factor binding protein.
Author: Culouscou, J M|Shoyab, M
PMID: 1709585
Journal: Int J Cancer. 1992 Dec 2;52(6):910-7.
Title: des-(1-3)-IGF-I, an insulin-like growth factor analog used to mimic a potential IGF-II autocrine loop, promotes the differentiation of human colon-carcinoma cells.
Author: Remacle-Bonnet, M|Garrouste, F|el Atiq, F|Roccabianca, M|Marvaldi, J|Pommier, G
PMID: 1281142
Journal: Cancer Res. 1994 Dec 15;54(24):6563-70.
Title: Episomal expression of sense and antisense insulin-like growth factor (IGF)-binding protein-4 complementary DNA alters the mitogenic response of a human colon cancer cell line (HT-29) by mechanisms that are independent of and dependent upon IGF-I.
Author: Singh, P|Dai, B|Dhruva, B|Widen, S G
PMID: 7527300
Journal: J Clin Invest. 1995 Jul;96(1):192-200.
Title: Cell polarity of the insulin-like growth factor system in human intestinal epithelial cells. Unique apical sorting of insulin-like growth factor binding protein-6 in differentiated human colon cancer cells.
Author: Remacle-Bonnet, M|Garrouste, F|el Atiq, F|Marvaldi, J|Pommier, G
PMID: 7542277
Journal: Endocrinology. 1996 May;137(5):1764-74.
Title: Proliferation and differentiation of a human colon cancer cell line (CaCo2) is associated with significant changes in the expression and secretion of insulin-like growth factor (IGF) IGF-II and IGF binding protein-4: role of IGF-II.
Author: Singh, P|Dai, B|Yallampalli, U|Lu, X|Schroy, P C
PMID: 8612513
Journal: Am J Physiol. 1996 Nov;271(5 Pt 1):E922-31.
Title: Expression of IGFBP-2, -3, and -4 mRNA during differentiation of Caco-2 colon epithelial cells.
Author: Hoeflich, A|Yang, Y|Huber, S|Rascher, W|Koepf, G|Blum, W F|Heinz-Erian, P|Kolb, H J|Kiess, W
PMID: 8944682
Journal: Endocrinology. 1997 Jan;138(1):332-43.
Title: Cloning of the functional promoter for human insulin-like growth factor binding protein-4 gene: endogenous regulation.
Author: Dai, B|Widen, S G|Mifflin, R|Singh, P
PMID: 8977421
Journal: Br J Cancer. 1997;76(1):60-6.
Title: Insulin-like growth factors and their binding proteins in human colonocytes: preferential degradation of insulin-like growth factor binding protein 2 in colonic cancers.
Author: Michell, N P|Langman, M J|Eggo, M C
PMID: 9218734
Journal: Int J Cancer. 1997 Sep 4;72(5):835-43.
Title: Surface-bound plasmin induces selective proteolysis of insulin-like-growth-factor (IGF)-binding protein-4 (IGFBP-4) and promotes autocrine IGF-II bio-availability in human colon-carcinoma cells.
Author: Remacle-Bonnet, M M|Garrouste, F L|Pommier, G J
PMID: 9311602
Journal: Growth Factors. 1997;14(4):269-77.
Title: Insulin-like growth factor binding proteins as mediators of IGF-I effects on colon cancer cell proliferation.
Author: Michell, N P|Dent, S|Langman, M J|Eggo, M C
PMID: 9386991
Journal: Cancer Res. 1998 Sep 1;58(17):4008-14.
Title: Regulation of vascular endothelial growth factor expression in human colon cancer by insulin-like growth factor-I.
Author: Akagi, Y|Liu, W|Zebrowski, B|Xie, K|Ellis, L M
PMID: 9731515
Journal: Mol Cell Endocrinol. 2001 Oct 25;183(1-2):141-9.
Title: Synthetic low-calcaemic vitamin D(3) analogues inhibit secretion of insulin-like growth factor II and stimulate production of insulin-like growth factor-binding protein-6 in conjunction with growth suppression of HT-29 colon cancer cells.
Author: Oh, Y S|Kim, E J|Schaffer, B S|Kang, Y H|Binderup, L|MacDonald, R G|Park, J H
PMID: 11604234
Journal: J Cell Physiol. 2002 Jan;190(1):92-100.
Title: Inhibition of Caco-2 cell proliferation by all-trans retinoic acid: role of insulin-like growth factor binding protein-6.
Author: Kim, Eun J|Kang, Young-Hee|Schaffer, Beverly S|Bach, Leon A|MacDonald, Richard G|Park, Jung H Y
PMID: 11807815
Journal: J Med Food. 2003 Fall;6(3):193-9.
Title: trans-10, cis-12 conjugated linoleic acid reduces insulin-like growth factor-II secretion in HT-29 human colon cancer cells.
Author: Cho, Han Jin|Lee, Hyun Sook|Chung, Cha-Kwon|Kang, Young-Hee|Ha, Yeong Lae|Park, Hyun-Suh|Park, Jung Han Yoon
PMID: 14585185
Journal: J Endocrinol. 2003 Dec;179(3):405-15.
Title: Interleukin-1beta (IL-1beta) and IL-6 modulate insulin-like growth factor-binding protein (IGFBP) secretion in colon cancer epithelial (Caco-2) cells.
Author: Street, M E|Miraki-Moud, F|Sanderson, I R|Savage, M O|Giovannelli, G|Bernasconi, S|Camacho-Hubner, C
PMID: 14656210
Journal: Oncogene. 2004 Apr 1;23(14):2454-64.
Title: Identification of a novel SP3 binding site in the promoter of human IGFBP4 gene: role of SP3 and AP-1 in regulating promoter activity in CaCo2 cells.
Author: Shen, Quiang|Singh, Pomila
PMID: 14767471
Journal: Cancer Res. 2004 Mar 1;64(5):1600-3.
Title: Insulin-like growth factor (IGF)-binding protein-4 inhibits colony formation of colorectal cancer cells by IGF-independent mechanisms.
Author: Diehl, Daniela|Hoeflich, Andreas|Wolf, Eckhard|Lahm, Harald
PMID: 14996716
Journal: Int J Cancer. 2005 Feb 10;113(4):588-99.
Title: Transcriptome analysis of a human colorectal cancer cell line shows molecular targets of insulin-like growth factor-binding protein-4 overexpression.
Author: Diehl, Daniela|Lahm, Harald|Wolf, Eckhard|Bauersachs, Stefan
PMID: 15455346
Journal: Neoplasia. 2005 Aug;7(8):741-7.
Title: Immunoprofiles of 11 biomarkers using tissue microarrays identify prognostic subgroups in colorectal cancer.
Author: Knosel, Thomas|Emde, Anna|Schluns, Karsten|Chen, Yuan|Jurchott, Karsten|Krause, Matthias|Dietel, Manfred|Petersen, Iver
PMID: 16207476
Journal: Int J Oncol. 2006 Jun;28(6):1317-25.
Title: Biology of insulin-like growth factor binding protein-4 and its role in cancer (review).
Author: Durai, Rajaraman|Davies, Mark|Yang, Wenxuan|Yang, Shi Yu|Seifalian, Alexander|Goldspink, Geoffrey|Winslet, Marc
PMID: 16685432
Journal: Int J Oncol. 2007 Apr;30(4):883-8.
Title: Insulin-like growth factor binding protein-4 gene therapy increases apoptosis by altering Bcl-2 and Bax proteins and decreases angiogenesis in colorectal cancer.
Author: Durai, Rajaraman|Yang, Shi Yu|Sales, Kevin M|Seifalian, Alexander M|Goldspink, Geoffrey|Winslet, Marc C
PMID: 17332927
Journal: Genome Biol. 2007;8(7):R131.
Title: Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer.
Author: Kaiser, Sergio|Park, Young-Kyu|Franklin, Jeffrey L|Halberg, Richard B|Yu, Ming|Jessen, Walter J|Freudenberg, Johannes|Chen, Xiaodi|Haigis, Kevin|Jegga, Anil G|Kong, Sue|Sakthivel, Bhuvaneswari|Xu, Huan|Reichling, Timothy|Azhar, Mohammad|Boivin, Gregory P|
PMID: 17615082
Journal: Colorectal Dis. 2007 Sep;9(7):625-31.
Title: Increased apoptosis and decreased proliferation of colorectal cancer cells using insulin-like growth factor binding protein-4 gene delivered locally by gene transfer.
Author: Durai, R|Yang, S Y|Sales, K M|Seifalian, A M|Goldspink, G|Winslet, M C
PMID: 17824980
Journal: World J Surg Oncol. 2007 Nov 7;5:128.
Title: Role of insulin-like growth factor binding protein-4 in prevention of colon cancer.
Author: Durai, Rajaraman|Yang, Shi Y|Seifalian, Alexander M|Goldspink, Geoffrey|Winslet, Marc C
PMID: 17988381
Journal: Mol Carcinog. 2008 Jan;47(1):9-21.
Title: Microarray analysis reveals that leptin induces autocrine/paracrine cascades to promote survival and proliferation of colon epithelial cells in an Apc genotype-dependent fashion.
Author: Fenton, Jenifer I|Lavigne, Jackie A|Perkins, Susan N|Liu, Huaitian|Chandramouli, Gadisetti V R|Shih, Joanna H|Hord, Norman G|Hursting, Stephen D
PMID: 17620308
Journal: Am J Physiol Gastrointest Liver Physiol. 2013 Jul 1;305(1):G74-83.
Title: SOX9 directly regulates IGFBP-4 in the intestinal epithelium.
Author: Shi, Zhongcheng|Chiang, Chi-I|Mistretta, Toni-Ann|Major, Angela|Mori-Akiyama, Yuko
PMID: 23660500
Journal: Peptides. 2017 May;91:49-57.
Title: Glucagon-like petide-2 acts on colon cancer myofibroblasts to stimulate proliferation, migration and invasion of both myofibroblasts and cancer cells via the IGF pathway.
Author: Shawe-Taylor, Marianne|Kumar, J Dinesh|Holden, Whitney|Dodd, Steven|Varga, Akos|Giger, Olivier|Varro, Andrea|Dockray, Graham J
PMID: 28363795