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Gene >> IGFBP2

Journal: Int J Cancer. 1992 Jul 9;51(5):818-21.
Title: Insulin-like growth-factor-binding protein gene expression and protein production by human tumour cell lines.
Author: Reeve, J G|Kirby, L B|Brinkman, A|Hughes, S A|Schwander, J|Bleehen, N M
PMID: 1377187
Journal: Int J Cancer. 1994 May 15;57(4):491-7.
Title: Alterations in serum levels of insulin-like growth factors and insulin-like growth-factor-binding proteins in patients with colorectal cancer.
Author: el Atiq, F|Garrouste, F|Remacle-Bonnet, M|Sastre, B|Pommier, G
PMID: 7514152
Journal: J Clin Invest. 1995 Jul;96(1):192-200.
Title: Cell polarity of the insulin-like growth factor system in human intestinal epithelial cells. Unique apical sorting of insulin-like growth factor binding protein-6 in differentiated human colon cancer cells.
Author: Remacle-Bonnet, M|Garrouste, F|el Atiq, F|Marvaldi, J|Pommier, G
PMID: 7542277
Journal: Endocrinology. 1996 May;137(5):1764-74.
Title: Proliferation and differentiation of a human colon cancer cell line (CaCo2) is associated with significant changes in the expression and secretion of insulin-like growth factor (IGF) IGF-II and IGF binding protein-4: role of IGF-II.
Author: Singh, P|Dai, B|Yallampalli, U|Lu, X|Schroy, P C
PMID: 8612513
Journal: Am J Physiol. 1996 Nov;271(5 Pt 1):E922-31.
Title: Expression of IGFBP-2, -3, and -4 mRNA during differentiation of Caco-2 colon epithelial cells.
Author: Hoeflich, A|Yang, Y|Huber, S|Rascher, W|Koepf, G|Blum, W F|Heinz-Erian, P|Kolb, H J|Kiess, W
PMID: 8944682
Journal: Br J Cancer. 1997;76(1):60-6.
Title: Insulin-like growth factors and their binding proteins in human colonocytes: preferential degradation of insulin-like growth factor binding protein 2 in colonic cancers.
Author: Michell, N P|Langman, M J|Eggo, M C
PMID: 9218734
Journal: Int J Cancer. 1997 Sep 4;72(5):835-43.
Title: Surface-bound plasmin induces selective proteolysis of insulin-like-growth-factor (IGF)-binding protein-4 (IGFBP-4) and promotes autocrine IGF-II bio-availability in human colon-carcinoma cells.
Author: Remacle-Bonnet, M M|Garrouste, F L|Pommier, G J
PMID: 9311602
Journal: Growth Factors. 1997;14(4):269-77.
Title: Insulin-like growth factor binding proteins as mediators of IGF-I effects on colon cancer cell proliferation.
Author: Michell, N P|Dent, S|Langman, M J|Eggo, M C
PMID: 9386991
Journal: FEBS Lett. 1998 Sep 4;434(3):329-34.
Title: Insulin-like growth factor-binding protein-2 inhibits proliferation of human embryonic kidney fibroblasts and of IGF-responsive colon carcinoma cell lines.
Author: Hoflich, A|Lahm, H|Blum, W|Kolb, H|Wolf, E
PMID: 9742949
Journal: Growth Horm IGF Res. 1998 Dec;8(6):473-9.
Title: Role of insulin-like growth factor-I (IGF-I) receptor, IGF-I, and IGF binding protein-2 in human colorectal cancers.
Author: Mishra, L|Bass, B|Ooi, B S|Sidawy, A|Korman, L
PMID: 10985759
Journal: J Clin Endocrinol Metab. 2000 Sep;85(9):3402-8.
Title: Circulating insulin-like growth factor II and colorectal adenomas.
Author: Renehan, A G|Painter, J E|O'Halloran, D|Atkin, W S|Potten, C S|O'Dwyer, S T|Shalet, S M
PMID: 10999841
Journal: J Natl Cancer Inst. 2000 Oct 4;92(19):1592-600.
Title: Serum C-peptide, insulin-like growth factor (IGF)-I, IGF-binding proteins, and colorectal cancer risk in women.
Author: Kaaks, R|Toniolo, P|Akhmedkhanov, A|Lukanova, A|Biessy, C|Dechaud, H|Rinaldi, S|Zeleniuch-Jacquotte, A|Shore, R E|Riboli, E
PMID: 11018095
Journal: Br J Cancer. 2000 Nov;83(10):1344-50.
Title: Elevated serum insulin-like growth factor (IGF)-II and IGF binding protein-2 in patients with colorectal cancer.
Author: Renehan, A G|Jones, J|Potten, C S|Shalet, S M|O'Dwyer, S T
PMID: 11044360
Journal: Mol Cell Endocrinol. 2001 Oct 25;183(1-2):141-9.
Title: Synthetic low-calcaemic vitamin D(3) analogues inhibit secretion of insulin-like growth factor II and stimulate production of insulin-like growth factor-binding protein-6 in conjunction with growth suppression of HT-29 colon cancer cells.
Author: Oh, Y S|Kim, E J|Schaffer, B S|Kang, Y H|Binderup, L|MacDonald, R G|Park, J H
PMID: 11604234
Journal: Clin Endocrinol (Oxf). 2001 Apr;54(4):499-508.
Title: Increased levels of insulin-like growth factor binding protein-2 in sera and tumours from patients with colonic neoplasia with and without acromegaly.
Author: Miraki-Moud, F|Jenkins, P J|Fairclough, P D|Jordan, S|Bustin, S A|Jones, A M|Lowe, D G|Monson, J P|Grossman, A B|Besser, G M|Camacho-Hubner, C
PMID: 11318786
Journal: J Cell Physiol. 2002 Jan;190(1):92-100.
Title: Inhibition of Caco-2 cell proliferation by all-trans retinoic acid: role of insulin-like growth factor binding protein-6.
Author: Kim, Eun J|Kang, Young-Hee|Schaffer, Beverly S|Bach, Leon A|MacDonald, Richard G|Park, Jung H Y
PMID: 11807815
Journal: J Natl Cancer Inst. 2002 Jul 3;94(13):972-80.
Title: Insulin, insulin-like growth factor-I (IGF-I), IGF binding proteins, their biologic interactions, and colorectal cancer.
Author: Sandhu, Manjinder S|Dunger, David B|Giovannucci, Edward L
PMID: 12096082
Journal: Am J Physiol Gastrointest Liver Physiol. 2002 Aug;283(2):G357-67.
Title: Trans-10,cis-12-conjugated linoleic acid inhibits Caco-2 colon cancer cell growth.
Author: Kim, Eun J|Holthuizen, P Elly|Park, Hyun S|Ha, Yeong L|Jung, Kyeong C|Park, Jung H Y
PMID: 12121883
Journal: Cancer Epidemiol Biomarkers Prev. 2002 Sep;11(9):901-5.
Title: Insulin-like growth factor II and colorectal cancer risk in women.
Author: Hunt, Kelly J|Toniolo, Paolo|Akhmedkhanov, Arslan|Lukanova, Annekatrin|Dechaud, Henri|Rinaldi, Sabina|Zeleniuch-Jacquotte, Anne|Shore, Roy E|Riboli, Elio|Kaaks, Rudolf
PMID: 12223436
Journal: Int J Cancer. 2003 Oct 20;107(1):89-93.
Title: Plasma insulin, IGF-binding proteins-1 and -2 and risk of colorectal cancer: a prospective study in northern Sweden.
Author: Palmqvist, Richard|Stattin, Par|Rinaldi, Sabina|Biessy, Carine|Stenling, Roger|Riboli, Elio|Hallmans, Goran|Kaaks, Rudolf
PMID: 12925961
Journal: J Med Food. 2003 Fall;6(3):193-9.
Title: trans-10, cis-12 conjugated linoleic acid reduces insulin-like growth factor-II secretion in HT-29 human colon cancer cells.
Author: Cho, Han Jin|Lee, Hyun Sook|Chung, Cha-Kwon|Kang, Young-Hee|Ha, Yeong Lae|Park, Hyun-Suh|Park, Jung Han Yoon
PMID: 14585185
Journal: J Endocrinol. 2003 Dec;179(3):405-15.
Title: Interleukin-1beta (IL-1beta) and IL-6 modulate insulin-like growth factor-binding protein (IGFBP) secretion in colon cancer epithelial (Caco-2) cells.
Author: Street, M E|Miraki-Moud, F|Sanderson, I R|Savage, M O|Giovannelli, G|Bernasconi, S|Camacho-Hubner, C
PMID: 14656210
Journal: Horm Metab Res. 2003 Nov-Dec;35(11-12):816-21.
Title: Increased activity of catalase in tumor cells overexpressing IGFBP-2.
Author: Hoeflich, A|Fettscher, O|Preta, G|Lahm, H|Kolb, H J|Wolf, E|Weber, M M
PMID: 14710363
Journal: Scand J Gastroenterol. 2004 May;39(5):464-9.
Title: Expression patterns of cell cycle and apoptosis-related genes in a multidrug-resistant human colon carcinoma cell line.
Author: Fan, C W|Chan, C C|Chao, C C K|Fan, H A|Sheu, D L|Chan, E C
PMID: 15180185
Journal: Am J Clin Nutr. 2007 Nov;86(5):1456-62.
Title: Lycopene supplementation elevates circulating insulin-like growth factor binding protein-1 and -2 concentrations in persons at greater risk of colorectal cancer.
Author: Vrieling, Alina|Voskuil, Dorien W|Bonfrer, Johannes M|Korse, Catharina M|van Doorn, Jaap|Cats, Annemieke|Depla, Annekatrien C|Timmer, Robin|Witteman, Ben J|van Leeuwen, Flora E|Van't Veer, Laura J|Rookus, Matti A|Kampman, Ellen
PMID: 17991659
Journal: Int J Cancer. 2007 Jul 15;121(2):368-76.
Title: Serum C-peptide, IGFBP-1 and IGFBP-2 and risk of colon and rectal cancers in the European Prospective Investigation into Cancer and Nutrition.
Author: Jenab, Mazda|Riboli, Elio|Cleveland, Rebecca J|Norat, Teresa|Rinaldi, Sabina|Nieters, Alexandra|Biessy, Carine|Tjonneland, Ann|Olsen, Anja|Overvad, Kim|Gronbaek, Henning|Clavel-Chapelon, Francoise|Boutron-Ruault, Marie-Christine|Linseisen, Jakob|Boeing, H
PMID: 17372899
Journal: J Nutr. 2007 Feb;137(2):379-83.
Title: Isolated isoflavones do not affect the circulating insulin-like growth factor system in men at increased colorectal cancer risk.
Author: Vrieling, Alina|Rookus, Matti A|Kampman, Ellen|Bonfrer, Johannes M G|Korse, Catharina M|van Doorn, Jaap|Lampe, Johanna W|Cats, Annemieke|Witteman, Ben J M|van Leeuwen, Flora E|van't Veer, Laura J|Voskuil, Dorien W
PMID: 17237315
Journal: Cancer Sci. 2007 May;98(5):685-91.
Title: Matrix metalloproteinase-7 triggers the matricrine action of insulin-like growth factor-II via proteinase activity on insulin-like growth factor binding protein 2 in the extracellular matrix.
Author: Miyamoto, Shin'ichi|Nakamura, Michio|Yano, Keiichi|Ishii, Genichiro|Hasebe, Takahiro|Endoh, Yasushi|Sangai, Takafumi|Maeda, Hiroyuki|Shi-Chuang, Zhang|Chiba, Tsutomu|Ochiai, Atsushi
PMID: 17359288
Journal: Mol Carcinog. 2008 Jan;47(1):9-21.
Title: Microarray analysis reveals that leptin induces autocrine/paracrine cascades to promote survival and proliferation of colon epithelial cells in an Apc genotype-dependent fashion.
Author: Fenton, Jenifer I|Lavigne, Jackie A|Perkins, Susan N|Liu, Huaitian|Chandramouli, Gadisetti V R|Shih, Joanna H|Hord, Norman G|Hursting, Stephen D
PMID: 17620308
Journal: Oncogene. 2008 Jul 3;27(29):4024-33.
Title: Autocrine induction of invasion and metastasis by tumor-associated trypsin inhibitor in human colon cancer cells.
Author: Gouyer, V|Fontaine, D|Dumont, P|de Wever, O|Fontayne-Devaud, H|Leteurtre, E|Truant, S|Delacour, D|Drobecq, H|Kerckaert, J-P|de Launoit, Y|Bracke, M|Gespach, C|Desseyn, J-L|Huet, G
PMID: 18317448
Journal: Cancer Epidemiol Biomarkers Prev. 2008 Oct;17(10):2585-93.
Title: No effect of red clover-derived isoflavone intervention on the insulin-like growth factor system in women at increased risk of colorectal cancer.
Author: Vrieling, Alina|Rookus, Matti A|Kampman, Ellen|Bonfrer, Johannes M G|Bosma, Astrid|Cats, Annemieke|van Doorn, Jaap|Korse, Catharina M|Witteman, Ben J M|van Leeuwen, Flora E|van't Veer, Laura J|Voskuil, Dorien W
PMID: 18842999
Journal: Int J Cancer. 2009 May 1;124(9):2220-5.
Title: IGFBP-2 overexpression reduces the appearance of dysplastic aberrant crypt foci and inhibits growth of adenomas in chemically induced colorectal carcinogenesis.
Author: Diehl, Daniela|Hessel, Esther|Oesterle, Doris|Renner-Muller, Ingrid|Elmlinger, Martin|Langhammer, Martina|Gottlicher, Martin|Wolf, Eckhard|Lahm, Harald|Hoeflich, Andreas
PMID: 19142966
Journal: Adv Med Sci. 2009;54(1):51-8.
Title: IGF-I, IGF-II, IGFBP2, IGFBP3 and acid-labile subunit (ALS) in colorectal cancer patients before surgery and during one year follow up in relation to age.
Author: Sztefko, K|Hodorowicz-Zaniewska, D|Popiela, T|Richter, P
PMID: 19482725
Journal: J Clin Endocrinol Metab. 2010 Apr;95(4):1717-25.
Title: Plasma insulin-like growth factor-binding protein-2 levels as diagnostic and prognostic biomarker of colorectal cancer.
Author: Liou, Jyh-Ming|Shun, Chia-Tung|Liang, Jin-Tung|Chiu, Han-Mo|Chen, Mei-Jyh|Chen, Chien-Chuan|Wang, Hsiu-Po|Wu, Ming-Shiang|Lin, Jaw-Town
PMID: 20157191
Journal: Int J Cancer. 2011 Apr 15;128(8):1843-51.
Title: The development of composite circulating biomarker models for use in anticancer drug clinical development.
Author: Lancashire, Lee J|Roberts, Darren L|Dive, Caroline|Renehan, Andrew G
PMID: 20549702
Journal: Eur J Med Res. 2011 Oct 10;16(10):451-6.
Title: Do insulin-like growth factor associated proteins qualify as a tumor marker? Results of a prospective study in 163 cancer patients.
Author: Matuschek, C|Rudoy, M|Peiper, M|Gerber, P A|Hoff, N P|Buhren, B A|Flehmig, B|Budach, W|Knoefel, W T|Bojar, H|Prisack, H B|Steinbach, G|Shukla, V|Schwarz, A|Kammers, K|Erhardt, A|Scherer, A|Bolke, E|Schauer, M
PMID: 22024424
Journal: Cancer Prev Res (Phila). 2012 Apr;5(4):655-64.
Title: Increased plasma levels of the APC-interacting protein MAPRE1, LRG1, and IGFBP2 preceding a diagnosis of colorectal cancer in women.
Author: Ladd, Jon J|Busald, Tina|Johnson, Melissa M|Zhang, Qing|Pitteri, Sharon J|Wang, Hong|Brenner, Dean E|Lampe, Paul D|Kucherlapati, Raju|Feng, Ziding|Prentice, Ross L|Hanash, Samir M
PMID: 22277732
Journal: Ann Oncol. 2012 Sep;23(9):2415-22.
Title: Elevated serum antibodies against insulin-like growth factor-binding protein-2 allow detecting early-stage cancers: evidences from glioma and colorectal carcinoma studies.
Author: Li, Y|Jiang, T|Zhang, J|Zhang, B|Yang, W|You, G|Xu, K|Wu, J|Luo, C|Song, S W
PMID: 22357443
Journal: Mol Biol Rep. 2013 May;40(5):3583-90.
Title: Circulation insulin-like growth factor peptides and colorectal cancer risk: an updated systematic review and meta-analysis.
Author: Chi, Feng|Wu, Rong|Zeng, Yue-can|Xing, Rui|Liu, Yang
PMID: 23269623
Journal: Free Radic Biol Med. 2013 Dec;65:1195-1200.
Title: Detection and identification of oxidized insulin-like growth factor-binding proteins and receptors in patients with colorectal carcinoma.
Author: Nedic, Olgica|Robajac, Dragana|Sunderic, Milos|Miljus, Goran|Dukanovic, Blagoje|Malenkovic, Vesna
PMID: 24051179
Journal: Clin Colorectal Cancer. 2013 Dec;12(4):267-274.e2.
Title: The prognostic role of ephrin A2 and endothelial growth factor receptor pathway mediators in patients with advanced colorectal cancer treated with cetuximab.
Author: Strimpakos, Alexios|Pentheroudakis, George|Kotoula, Vassiliki|De Roock, Wendy|Kouvatseas, George|Papakostas, Pavlos|Makatsoris, Thomas|Papamichael, Demetris|Andreadou, Anna|Sgouros, Joseph|Zizi-Sermpetzoglou, Adamantia|Kominea, Athina|Televantou, Despina|
PMID: 24050852
Journal: Oncogene. 2013 Jul 4;32(27):3220-30.
Title: Global analysis of L1-transcriptomes identified IGFBP-2 as a target of ezrin and NF-kappaB signaling that promotes colon cancer progression.
Author: Ben-Shmuel, A|Shvab, A|Gavert, N|Brabletz, T|Ben-Ze'ev, A
PMID: 22869145
Journal: Exp Mol Pathol. 2014 Feb;96(1):48-53.
Title: Molecular forms of the insulin-like growth factor-binding protein-2 in patients with colorectal cancer.
Author: Sunderic, Milos|Dukanovic, Blagoje|Malenkovic, Vesna|Nedic, Olgica
PMID: 24275430
Journal: Bull Exp Biol Med. 2014 Mar;156(5):684-8.
Title: Insulin-like growth factors (IGF), IGF-binding proteins (IGFBP), and vascular endothelial growth factor (VEGF) in blood serum of patients with colorectal cancer.
Author: Kushlinskii, N E|Gershtein, E S|Nikolaev, A A|Delektorskaya, V V|Korotkova, E A|Dvorova, E K|Kostyleva, O I
PMID: 24770758
Journal: Cancer Epidemiol Biomarkers Prev. 2014 Sep;23(9):1852-62.
Title: Body size, physical activity, early-life energy restriction, and associations with methylated insulin-like growth factor-binding protein genes in colorectal cancer.
Author: Simons, Colinda C J M|van den Brandt, Piet A|Stehouwer, Coen D A|van Engeland, Manon|Weijenberg, Matty P
PMID: 24972776
Journal: Ann Oncol. 2015 Jan;26(1):252-3.
Title: Letter to the editor concerning 'Elevated serum antibodies against insulin-like growth factor-binding protein-2 allow detecting early-stage cancers: evidences from glioma and colorectal carcinoma studies'.
Author: Hassan, W A|Bjerre, M|Hjortebjerg, R|Magnusson, N E|Ramshanker, N|Frystyk, J
PMID: 25355718
Journal: Mol Cancer Ther. 2015 Apr;14(4):1048-56.
Title: Biomarker signatures correlate with clinical outcome in refractory metastatic colorectal cancer patients receiving bevacizumab and everolimus.
Author: Liu, Yingmiao|Starr, Mark D|Brady, John C|Rushing, Christel|Bulusu, Anuradha|Pang, Herbert|Honeycutt, Wanda|Amara, Anthony|Altomare, Ivy|Uronis, Hope E|Hurwitz, Herbert I|Nixon, Andrew B
PMID: 25695956
Journal: PLoS One. 2015 Mar 20;10(3):e0120425.
Title: Blood-based protein biomarker panel for the detection of colorectal cancer.
Author: Fung, Kim Y C|Tabor, Bruce|Buckley, Michael J|Priebe, Ilka K|Purins, Leanne|Pompeia, Celine|Brierley, Gemma V|Lockett, Trevor|Gibbs, Peter|Tie, Jeanne|McMurrick, Paul|Moore, James|Ruszkiewicz, Andrew|Nice, Edouard|Adams, Timothy E|Burgess, Antony|Cosgrove
PMID: 25793510
Journal: F1000Res. 2015 Apr 24;4:99.
Title: Linking patient outcome to high throughput protein expression data identifies novel regulators of colorectal adenocarcinoma aggressiveness.
Author: French, Christi L|Ye, Fei|Revetta, Frank|Zhang, Bing|Coffey, Robert J|Washington, M Kay|Deane, Natasha G|Beauchamp, R Daniel|Weaver, Alissa M
PMID: 26097693
Journal: Oncotarget. 2017 Jan 10;8(2):3430-3440.
Title: A four gene signature predictive of recurrent prostate cancer.
Author: Komisarof, Justin|McCall, Matthew|Newman, Laurel|Bshara, Wiam|Mohler, James L|Morrison, Carl|Land, Hartmut
PMID: 27966447
Journal: Anticancer Res. 2017 Apr;37(4):1779-1785.
Title: Expression of RNA-binding Motif Protein 3 (RBM3) and Cold-inducible RNA-binding protein (CIRP) Is Associated with Improved Clinical Outcome in Patients with Colon Cancer.
Author: Jang, Ho Hee|Lee, Hae Na|Kim, So-Young|Hong, Suntaek|Lee, Won-Suk
PMID: 28373441
Journal: PeerJ. 2018 Mar 6;6:e4506.
Title: Cellular prion protein and gamma-synuclein overexpression in LS 174T colorectal cancer cell drives endothelial proliferation-to-differentiation switch.
Author: Ong, Sing-Hui|Goh, Kai-Wey|Chieng, Cornelius Kwang-Lee|Say, Yee-How
PMID: 29527422