Primary Site >> Colorectal Cancer

Gene >> IGF2R

Journal: Arch Biochem Biophys. 1992 Oct;298(1):176-81.
Title: Biosynthesis and endocytosis of lysosomal enzymes in human colon carcinoma SW 1116 cells: impaired internalization of plasma membrane-associated cation-independent mannose 6-phosphate receptor.
Author: Braulke, T|Mach, L|Hoflack, B|Glossl, J
PMID: 1326252
Journal: Curr Probl Cancer. 1997 Sep-Oct;21(5):233-300.
Title: Molecular biology of colorectal cancer.
Author: Gryfe, R|Swallow, C|Bapat, B|Redston, M|Gallinger, S|Couture, J
PMID: 9438104
Journal: Pathol Int. 1998 Aug;48(8):586-94.
Title: Microsatellite instability in young patients with colorectal cancer.
Author: Kim, W H|Lee, H W|Park, S H|Kim, Y I|Chi, J G
PMID: 9736405
Journal: Cancer Res. 1998 Nov 1;58(21):4802-4.
Title: Sequence alterations of insulin-like growth factor binding protein 3 in neoplastic and normal gastrointestinal tissues.
Author: Zou, T|Fleisher, A S|Kong, D|Yin, J|Souza, R F|Wang, S|Smolinski, K N|Abraham, J M|Meltzer, S J
PMID: 9809981
Journal: J Biol Chem. 1999 Jul 9;274(28):20002-10.
Title: The mannose 6-phosphate/insulin-like growth factor-II receptor is a substrate of type V transforming growth factor-beta receptor.
Author: Liu, Q|Grubb, J H|Huang, S S|Sly, W S|Huang, J S
PMID: 10391950
Journal: Oncogene. 1999 Jul 15;18(28):4063-8.
Title: Expression of the wild-type insulin-like growth factor II receptor gene suppresses growth and causes death in colorectal carcinoma cells.
Author: Souza, R F|Wang, S|Thakar, M|Smolinski, K N|Yin, J|Zou, T T|Kong, D|Abraham, J M|Toretsky, J A|Meltzer, S J
PMID: 10435587
Journal: Int J Colorectal Dis. 2000 Apr;15(2):83-6.
Title: Genetic analysis of multiple sporadic colon carcinomas from a single patient.
Author: Barnetson, R A|Symons, P|Robinson, B G|Schnitzler, M
PMID: 10855548
Journal: Gut. 2000 Jul;47(1):37-42.
Title: DNA microsatellite instability and mismatch repair protein loss in adenomas presenting in hereditary non-polyposis colorectal cancer.
Author: Iino, H|Simms, L|Young, J|Arnold, J|Winship, I M|Webb, S I|Furlong, K L|Leggett, B|Jass, J R
PMID: 10861262
Journal: Gut. 2000 Jul;47(1):43-9.
Title: Neoplastic progression occurs through mutator pathways in hyperplastic polyposis of the colorectum.
Author: Jass, J R|Iino, H|Ruszkiewicz, A|Painter, D|Solomon, M J|Koorey, D J|Cohn, D|Furlong, K L|Walsh, M D|Palazzo, J|Edmonston, T B|Fishel, R|Young, J|Leggett, B A
PMID: 10861263
Journal: Gan To Kagaku Ryoho. 2000 Jul;27(8):1253-9.
Title: [Mechanism of resistance to growth inhibition by transforming growth factor-beta 1 (TGF-beta 1) in primary lung cancer and new molecular targets in therapy].
Author: Gemma, A|Uematsu, K|Hagiwara, K|Takenoshita, S|Kudoh, S
PMID: 10945024
Journal: Genes Chromosomes Cancer. 2000 Oct;29(2):130-6.
Title: Mutations associated with microsatellite unstable colorectal carcinomas exhibit widespread intratumoral heterogeneity.
Author: Barnetson, R|Jass, J|Tse, R|Eckstein, R|Robinson, B|Schnitzler, M
PMID: 10959092
Journal: Hum Mutat. 2001;18(1):25-31.
Title: Mannose 6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) variants in American and Japanese populations.
Author: Killian, J K|Oka, Y|Jang, H S|Fu, X|Waterland, R A|Sohda, T|Sakaguchi, S|Jirtle, R L
PMID: 11438990
Journal: Am J Pathol. 2002 Jun;160(6):1953-8.
Title: Endometrial and colorectal tumors from patients with hereditary nonpolyposis colon cancer display different patterns of microsatellite instability.
Author: Kuismanen, Shannon A|Moisio, Anu-Liisa|Schweizer, Pascal|Truninger, Kaspar|Salovaara, Reijo|Arola, Johanna|Butzow, Ralf|Jiricny, Josef|Nystrom-Lahti, Minna|Peltomaki, Paivi
PMID: 12057899
Journal: Genes Chromosomes Cancer. 2003 May;37(1):29-35.
Title: Identification of microsatellite instability and mismatch repair gene mutations in breast cancer cell lines.
Author: Seitz, Susanne|Wassmuth, Peter|Plaschke, Jens|Schackert, Hans K|Karsten, Uwe|Santibanez-Koref, Mauro-F|Schlag, Peter M|Scherneck, Siegfried
PMID: 12661003
Journal: J Biol Chem. 2004 Sep 17;279(38):39982-8.
Title: Defective acidification of intracellular organelles results in aberrant secretion of cathepsin D in cancer cells.
Author: Kokkonen, Nina|Rivinoja, Antti|Kauppila, Annika|Suokas, Marko|Kellokumpu, Ilmo|Kellokumpu, Sakari
PMID: 15258139
Journal: Oncogene. 2004 Oct 21;23(49):8158-70.
Title: Identification of cell surface and secreted proteins essential for tumor cell survival using a genetic suppressor element screen.
Author: Gelman, Marina S|Ye, X Katherine|Stull, Robert|Suhy, David|Jin, Liang|Ng, Dean|Than, Bruce|Ji, May|Pan, Alison|Perez, Paul|Sun, Yan|Yeung, Patricia|Garcia, Luz Maria|Harte, Rachel|Lu, Yan|Lamar, Elizabeth|Tavassoli, Roya|Kennedy, Scot|Osborn, Stephen|Chin
PMID: 15361835
Journal: Growth Horm IGF Res. 2005 Jun;15(3):215-22. Epub 2005 Apr 20.
Title: Interleukin-5 potentiates the growth response of Caco-2 cells to IGF-II: a role in colonic carcinogenesis complicating ulcerative colitis?
Author: Makins, Richard|Ballinger, Anne
PMID: 15935984
Journal: Proteins. 2006 Aug 15;64(3):758-68.
Title: Computational model for the IGF-II/IGF2r complex that is predictive of mutational and surface plasmon resonance data.
Author: Roche, Philippe|Brown, James|Denley, Adam|Forbes, Briony E|Wallace, John C|Jones, E Yvonne|Esnouf, Robert M
PMID: 16741994
Journal: J Cell Biochem. 2007 Jan 1;100(1):58-68.
Title: Insulin-like growth factors induce apoptosis as well as proliferation in LIM 1215 colon cancer cells.
Author: Fu, Ping|Thompson, Julian A|Leeding, Kerri S|Bach, Leon A
PMID: 16888814
Journal: BMC Cancer. 2010 Oct 27;10:587.
Title: Colorectal carcinomas with microsatellite instability display a different pattern of target gene mutations according to large bowel site of origin.
Author: Pinheiro, Manuela|Ahlquist, Terje|Danielsen, Stine A|Lind, Guro E|Veiga, Isabel|Pinto, Carla|Costa, Vera|Afonso, Luis|Sousa, Olga|Fragoso, Maria|Santos, Lucio|Henrique, Rui|Lopes, Paula|Lopes, Carlos|Lothe, Ragnhild A|Teixeira, Manuel R
PMID: 20979647
Journal: Dis Markers. 2012;32(2):133-41.
Title: IGF2R genetic variants, circulating IGF2 concentrations and colon cancer risk in African Americans and Whites.
Author: Hoyo, Cathrine|Murphy, Susan K|Schildkraut, Joellen M|Vidal, Adriana C|Skaar, David|Millikan, Robert C|Galanko, Joseph|Sandler, Robert S|Jirtle, Randy|Keku, Temitope
PMID: 22377707
Journal: J Gastroenterol Hepatol. 2012 Apr;27 Suppl 3:95-9.
Title: Genomic copy number of a carcinogenic single nucleotide polymorphism at 8q24 in non-risk allele colorectal cancer associated with insulin growth factor 2 receptor expression.
Author: Takahashi, Yusuke|Mimori, Koshi|Yamamoto, Ken|Watanabe, Masahiko|Tanaka, Jun-Ichi|Kudo, Shin-Ei|Sugihara, Ken-Ichi|Hase, Kazuo|Mochizuki, Hidetaka|Kusunoki, Masato|Yamada, Kazutaka|Shimada, Yasuhiro|Moriya, Yoshihiro|Mori, Masaki
PMID: 22486879
Journal: Free Radic Biol Med. 2013 Dec;65:1195-1200.
Title: Detection and identification of oxidized insulin-like growth factor-binding proteins and receptors in patients with colorectal carcinoma.
Author: Nedic, Olgica|Robajac, Dragana|Sunderic, Milos|Miljus, Goran|Dukanovic, Blagoje|Malenkovic, Vesna
PMID: 24051179
Journal: Cancer Causes Control. 2014 Feb;25(2):161-70.
Title: Racial differences in the association of insulin-like growth factor pathway and colorectal adenoma risk.
Author: Ochs-Balcom, Heather M|Vaughn, Caila B|Nie, Jing|Chen, Zhengyi|Thompson, Cheryl L|Parekh, Niyati|Tracy, Russell|Li, Li
PMID: 24194259
Journal: Int J Mol Sci. 2015 Oct 2;16(10):23615-29.
Title: Insulin-Like Growth Factor-2 Is Induced Following 5-Aminolevulinic Acid-Mediated Photodynamic Therapy in SW620 Human Colon Cancer Cell Line.
Author: Wozniak, Marta|Dus-Szachniewicz, Kamila|Ziolkowski, Piotr
PMID: 26445041
Journal: BMC Syst Biol. 2016 Feb 9;10:15.
Title: Quantitative analysis of insulin-like growth factor 2 receptor and insulin-like growth factor binding proteins to identify control mechanisms for insulin-like growth factor 1 receptor phosphorylation.
Author: Tian, Dan|Mitchell, Isaiah|Kreeger, Pamela K
PMID: 26861122
Journal: Ginekol Pol. 2016;87(8):598-604.
Title: Does IGF-1 play a role in the biology of endometrial cancer?
Author: Majchrzak-Baczmanska, Dominika|Malinowski, Andrzej
PMID: 27629137