Primary Site >> Colorectal Cancer

Gene >> IGF2R

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Ref: Biosynthesis and endocytosis of lysosomal enzymes in human colon carcinoma SW 1116 cells: impaired internalization of plasma membrane-associated cation-independent mannose 6-phosphate receptor.
PMID: 1326252
Ref: Molecular biology of colorectal cancer.
PMID: 9438104
Ref: Microsatellite instability in young patients with colorectal cancer.
PMID: 9736405
Ref: Sequence alterations of insulin-like growth factor binding protein 3 in neoplastic and normal gastrointestinal tissues.
PMID: 9809981
Ref: The mannose 6-phosphate/insulin-like growth factor-II receptor is a substrate of type V transforming growth factor-beta receptor.
PMID: 10391950
Ref: Expression of the wild-type insulin-like growth factor II receptor gene suppresses growth and causes death in colorectal carcinoma cells.
PMID: 10435587
Ref: Genetic analysis of multiple sporadic colon carcinomas from a single patient.
PMID: 10855548
Ref: DNA microsatellite instability and mismatch repair protein loss in adenomas presenting in hereditary non-polyposis colorectal cancer.
PMID: 10861262
Ref: Neoplastic progression occurs through mutator pathways in hyperplastic polyposis of the colorectum.
PMID: 10861263
Ref: [Mechanism of resistance to growth inhibition by transforming growth factor-beta 1 (TGF-beta 1) in primary lung cancer and new molecular targets in therapy].
PMID: 10945024
Ref: Mutations associated with microsatellite unstable colorectal carcinomas exhibit widespread intratumoral heterogeneity.
PMID: 10959092
Ref: Mannose 6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) variants in American and Japanese populations.
PMID: 11438990
Ref: Endometrial and colorectal tumors from patients with hereditary nonpolyposis colon cancer display different patterns of microsatellite instability.
PMID: 12057899
Ref: Identification of microsatellite instability and mismatch repair gene mutations in breast cancer cell lines.
PMID: 12661003
Ref: Defective acidification of intracellular organelles results in aberrant secretion of cathepsin D in cancer cells.
PMID: 15258139
Ref: Identification of cell surface and secreted proteins essential for tumor cell survival using a genetic suppressor element screen.
PMID: 15361835
Ref: Interleukin-5 potentiates the growth response of Caco-2 cells to IGF-II: a role in colonic carcinogenesis complicating ulcerative colitis?
PMID: 15935984
Ref: Computational model for the IGF-II/IGF2r complex that is predictive of mutational and surface plasmon resonance data.
PMID: 16741994
Ref: Insulin-like growth factors induce apoptosis as well as proliferation in LIM 1215 colon cancer cells.
PMID: 16888814
Ref: Colorectal carcinomas with microsatellite instability display a different pattern of target gene mutations according to large bowel site of origin.
PMID: 20979647
Ref: IGF2R genetic variants, circulating IGF2 concentrations and colon cancer risk in African Americans and Whites.
PMID: 22377707
Ref: Genomic copy number of a carcinogenic single nucleotide polymorphism at 8q24 in non-risk allele colorectal cancer associated with insulin growth factor 2 receptor expression.
PMID: 22486879
Ref: Detection and identification of oxidized insulin-like growth factor-binding proteins and receptors in patients with colorectal carcinoma.
PMID: 24051179
Ref: Racial differences in the association of insulin-like growth factor pathway and colorectal adenoma risk.
PMID: 24194259
Ref: Insulin-Like Growth Factor-2 Is Induced Following 5-Aminolevulinic Acid-Mediated Photodynamic Therapy in SW620 Human Colon Cancer Cell Line.
PMID: 26445041
Ref: Quantitative analysis of insulin-like growth factor 2 receptor and insulin-like growth factor binding proteins to identify control mechanisms for insulin-like growth factor 1 receptor phosphorylation.
PMID: 26861122
Ref: Does IGF-1 play a role in the biology of endometrial cancer?
PMID: 27629137