Literatures

Primary Site >> Liver Cancer

Gene >> IGF2

1.
Journal:	Cancer Res. 1992 May 1;52(9):2549-56.
Title:	Reactivation of insulin-like growth factor II during hepatocarcinogenesis in transgenic mice suggests a role in malignant growth.
Author:	Schirmacher, P\|Held, W A\|Yang, D\|Chisari, F V\|Rustum, Y\|Rogler, C E
PMID:	1568224

2.
Journal:	Oncogene. 1996 Apr 4;12(7):1589-92.
Title:	Allelic-expression imbalance of the insulin-like growth factor 2 gene in hepatocellular carcinoma and underlying disease.
Author:	Takeda, S\|Kondo, M\|Kumada, T\|Koshikawa, T\|Ueda, R\|Nishio, M\|Osada, H\|Suzuki, H\|Nagatake, M\|Washimi, O\|Takagi, K\|Takahashi, T\|Nakao, A\|Takahashi, T
PMID:	8622877

3.
Journal:	Lab Invest. 1996 Sep;75(3):307-11.
Title:	Increased expression of insulin-like growth factor 2 in hepatocellular carcinoma is primarily regulated at the transcriptional level.
Author:	Sohda, T\|Yun, K\|Iwata, K\|Soejima, H\|Okumura, M
PMID:	8804354

4.
Journal:	Oncogene. 1996 May 2;12(9):2003-9.
Title:	M6P/IGF2 receptor: a candidate breast tumor suppressor gene.
Author:	Hankins, G R\|De Souza, A T\|Bentley, R C\|Patel, M R\|Marks, J R\|Iglehart, J D\|Jirtle, R L
PMID:	8649861

5.
Journal:	Mol Carcinog. 1997 Apr;18(4):193-8.
Title:	Altered transcriptional regulation of the insulin-like growth factor 2 gene in human hepatocellular carcinoma.
Author:	Uchida, K\|Kondo, M\|Takeda, S\|Osada, H\|Takahashi, T\|Nakao, A\|Takahashi, T
PMID:	9142213

6.
Journal:	Cancer Res. 1997 May 15;57(10):2048-54.
Title:	Disrupted IGF2 promoter control by silencing of promoter P1 in human hepatocellular carcinoma.
Author:	Li, X\|Nong, Z\|Ekstrom, C\|Larsson, E\|Nordlinder, H\|Hofmann, W J\|Trautwein, C\|Odenthal, M\|Dienes, H P\|Ekstrom, T J\|Schirmacher, P
PMID:	9158004

7.
Journal:	Cancer Res. 1997 Oct 15;57(20):4615-23.
Title:	Genomic imprinting and Igf2 influence liver tumorigenesis and loss of heterozygosity in SV40 T antigen transgenic mice.
Author:	Haddad, R\|Held, W A
PMID:	9377577

8.
Journal:	Br J Cancer. 1997;76(12):1558-61.
Title:	Loss of heterozygosity at the mannose 6-phosphate insulin-like growth factor 2 receptor gene correlates with poor differentiation in early breast carcinomas.
Author:	Chappell, S A\|Walsh, T\|Walker, R A\|Shaw, J A
PMID:	9413941

9.
Journal:	Cancer Lett. 1997 Nov 11;119(2):143-8.
Title:	Biallelic expression of the H19 and IGF2 genes in hepatocellular carcinoma.
Author:	Kim, K S\|Lee, Y I
PMID:	9570364

10.
Journal:	Oncogene. 1998 Jan 15;16(2):203-9.
Title:	Reactivation of the maternally imprinted IGF2 allele in TGFalpha induced hepatocellular carcinomas in mice.
Author:	Harris, T M\|Rogler, L E\|Rogler, C E
PMID:	9464538

11.
Journal:	J Hum Genet. 1998;43(1):49-53.
Title:	In situ detection of insulin-like growth factor II (IGF2) and H19 gene expression in hepatocellular carcinoma.
Author:	Sohda, T\|Iwata, K\|Soejima, H\|Kamimura, S\|Shijo, H\|Yun, K
PMID:	9609998

12.
Journal:	J Gastroenterol Hepatol. 1998 Jan;13(1):47-51.
Title:	Case report: Insulin-like growth factor II expression in hepatocellular carcinoma with alcoholic liver fibrosis accompanied by hypoglycaemia.
Author:	Yamaguchi, M\|Kamimura, S\|Takada, J\|Iwata, K\|Iida, T\|Kobayashi, K\|Nakano, H\|Okada, Y\|Fujiimi, S\|Sohda, T\|Hizuka, N
PMID:	9737571

13.
Journal:	Mol Carcinog. 1998 Dec;23(4):248-53.
Title:	Loss of imprinting of the insulin-like growth factor II gene in mouse hepatocellular carcinoma cell lines.
Author:	Ooasa, T\|Karasaki, H\|Kanda, H\|Nomura, K\|Kitagawa, T\|Ogawa, K
PMID:	9869454

14.
Journal:	Am J Pathol. 2000 Oct;157(4):1393-403.
Title:	p57(KIP2) is not mutated in hepatoblastoma but shows increased transcriptional activity in a comparative analysis of the three imprinted genes p57(KIP2), IGF2, and H19.
Author:	Hartmann, W\|Waha, A\|Koch, A\|Goodyer, C G\|Albrecht, S\|von Schweinitz, D\|Pietsch, T
PMID:	11021841

15.
Journal:	Oncogene. 2000 Dec 14;19(54):6376-85.
Title:	The H19 endodermal enhancer is required for Igf2 activation and tumor formation in experimental liver carcinogenesis.
Author:	Vernucci, M\|Cerrato, F\|Besnard, N\|Casola, S\|Pedone, P V\|Bruni, C B\|Riccio, A
PMID:	11175353

16.
Journal:	Cytokine. 2000 Jul;12(7):1104-9.
Title:	IGF-II and IL-2 act synergistically to alter HDAC1 expression following treatments with trichostatin a.
Author:	Gray, S G\|Svechnikova, I\|Hartmann, W\|O'Connor, L\|Aguilar-Santelises, M\|Ekstrom, T J
PMID:	10880258

17.
Journal:	Oncogene. 2002 Jul 25;21(32):5006-15.
Title:	Cloning and characterization of a novel 90 kDa 'companion' auto-antigen of p62 overexpressed in cancer.
Author:	Soo Hoo, Linda\|Zhang, Jianying Y\|Chan, Edward K L
PMID:	12118381

18.
Journal:	Cancer Res. 2002 Jul 15;62(14):3939-44.
Title:	Comparison of gene expression profiles between hepatitis B virus- and hepatitis C virus-infected hepatocellular carcinoma by oligonucleotide microarray data on the basis of a supervised learning method.
Author:	Iizuka, Norio\|Oka, Masaaki\|Yamada-Okabe, Hisafumi\|Mori, Naohide\|Tamesa, Takao\|Okada, Toshimasa\|Takemoto, Norikazu\|Tangoku, Akira\|Hamada, Kenji\|Nakayama, Hironobu\|Miyamoto, Takanobu\|Uchimura, Shunji\|Hamamoto, Yoshihiko
PMID:	12124323

19.
Journal:	J Clin Invest. 2003 Jan;111(2):265-73.
Title:	A methylated oligonucleotide inhibits IGF2 expression and enhances survival in a model of hepatocellular carcinoma.
Author:	Yao, Xiaoming\|Hu, Ji-Fan\|Daniels, Mark\|Shiran, Hadas\|Zhou, Xiangjun\|Yan, Huifan\|Lu, Hongqi\|Zeng, Zhilan\|Wang, Qingxue\|Li, Tao\|Hoffman, Andrew R
PMID:	12531883

20.
Journal:	Cancer Genet Cytogenet. 2003 Sep;145(2):152-60.
Title:	Transcriptional profiling in hepatoblastomas using high-density oligonucleotide DNA array.
Author:	Nagata, Toshihito\|Takahashi, Yasuo\|Ishii, Yukimoto\|Asai, Satoshi\|Nishida, Yayoi\|Murata, Akiko\|Koshinaga, Tsugumichi\|Fukuzawa, Masahiro\|Hamazaki, Minoru\|Asami, Keiko\|Ito, Etsuro\|Ikeda, Hitoshi\|Takamatsu, Hideo\|Koike, Kenichi\|Kikuta, Atsushi\|Kuroiwa, Minoru
PMID:	12935928

21.
Journal:	Exp Mol Med. 2003 Aug 31;35(4):257-62.
Title:	Growth promotion of HepG2 hepatoma cells by antisense-mediated knockdown of glypican-3 is independent of insulin-like growth factor 2 signaling.
Author:	Sung, Young Kwan\|Hwang, Sung Young\|Farooq, Mohammad\|Kim, Jung-Chul\|Kim, Moon Kyu
PMID:	14508064

22.
Journal:	J Pathol. 2003 Nov;201(3):473-9.
Title:	Loss of parental-specific methylation at the IGF2 locus in human hepatocellular carcinoma.
Author:	Poirier, Karine\|Chalas, Celine\|Tissier, Frederique\|Couvert, Philippe\|Mallet, Vincent\|Carrie, Alain\|Marchio, Agnes\|Sarli, Dario\|Gicquel, Christine\|Chaussade, Stanislas\|Beljord, Cherif\|Chelly, Jamel\|Kerjean, Antoine\|Terris, Benoit
PMID:	14595760

23.
Journal:	Mol Carcinog. 2004 Jul;40(3):150-9.
Title:	Alterations in specific gene expression and focal neoplastic growth during spontaneous hepatocarcinogenesis in albumin-SV40 T antigen transgenic rats.
Author:	Dragan, Yvonne P\|Sargent, Linda M\|Babcock, Karlee\|Kinunen, Nina\|Pitot, Henry C
PMID:	15224347

24.
Journal:	Anticancer Res. 2004 Nov-Dec;24(6):4085-9.
Title:	Imbalance in expression levels of insulin-like growth factor 2 and H19 transcripts linked to progression of hepatocellular carcinoma.
Author:	Iizuka, Norio\|Oka, Masaaki\|Tamesa, Takao\|Hamamoto, Yoshihiko\|Yamada-Okabe, Hisafumi
PMID:	15736456

25.
Journal:	Intern Med. 2004 Sep;43(9):824-8.
Title:	Severe hypoglycemia and hypokalemia in association with liver metastases of gastric cancer.
Author:	Kato, Akihiko\|Bando, Etsuro\|Shinozaki, Shingo\|Yonemura, Yutaka\|Aiba, Motohiko\|Fukuda, Izumi\|Hizuka, Naomi\|Kameya, Toru
PMID:	15497518

26.
Journal:	Zhonghua Gan Zang Bing Za Zhi. 2004 Jun;12(6):347-9.
Title:	[Study on the expression and genomic imprinting status of insulin-like growth factor 2 gene in hepatocellular carcinoma].
Author:	Li, Hui\|Zhang, Nong
PMID:	15225429

27.
Journal:	Biochem Biophys Res Commun. 2004 Jun 11;318(4):916-9.
Title:	Oncofetal splice-pattern of the human H19 gene.
Author:	Matouk, Imad\|Ayesh, Basim\|Schneider, Tamar\|Ayesh, Suhail\|Ohana, Patricia\|de-Groot, Nathan\|Hochberg, Abraham\|Galun, Eithan
PMID:	15147959

28.
Journal:	Sichuan Da Xue Xue Bao Yi Xue Ban. 2004 Jul;35(4):466-9.
Title:	[The imprinting status and expression of insulin-like growth factor 2 gene in human hepatocellular carcinoma].
Author:	He, Wen-zhi\|Qin, Yang\|Li, Bo\|Liu, Jian-yu\|Sun, Zhi-lin\|Sun, Ze-fang
PMID:	15291100

29.
Journal:	Mol Cell Biol. 2005 Feb;25(4):1228-37.
Title:	The absence of p53 promotes metastasis in a novel somatic mouse model for hepatocellular carcinoma.
Author:	Lewis, Brian C\|Klimstra, David S\|Socci, Nicholas D\|Xu, Su\|Koutcher, Jason A\|Varmus, Harold E
PMID:	15684377

30.
Journal:	Biochem Biophys Res Commun. 2006 Jul 21;346(1):38-44.
Title:	IGF2 polymorphisms are associated with hepatitis B virus clearance and hepatocellular carcinoma.
Author:	Kim, Yoon Jun\|Yoon, Jung-Hwan\|Kim, Chung Yong\|Kim, Lyoung Hyo\|Park, Byung Lae\|Shin, Hyoung Doo\|Lee, Hyo-Suk
PMID:	16750516

31.
Journal:	Growth Horm IGF Res. 2006 Aug;16(4):211-6.
Title:	Clinical features of insulin-like growth factor-II producing non-islet-cell tumor hypoglycemia.
Author:	Fukuda, Izumi\|Hizuka, Naomi\|Ishikawa, Yukiko\|Yasumoto, Kumiko\|Murakami, Yuko\|Sata, Akira\|Morita, Junko\|Kurimoto, Makiko\|Okubo, Yumiko\|Takano, Kazue
PMID:	16860583

32.
Journal:	Int J Cancer. 2006 Dec 1;119(11):2557-66.
Title:	Impact of IGF-1R/EGFR cross-talks on hepatoma cell sensitivity to gefitinib.
Author:	Desbois-Mouthon, Christele\|Cacheux, Wulfran\|Blivet-Van Eggelpoel, Marie-Jose\|Barbu, Veronique\|Fartoux, Laetitia\|Poupon, Raoul\|Housset, Chantal\|Rosmorduc, Olivier
PMID:	16988945

33.
Journal:	Cancer Biol Ther. 2007 Oct;6(10):1532-8. Epub 2007 Jul 5.
Title:	Identification of candidate biomarkers for hepatocellular carcinoma through pre-cancerous expression analysis in an HBx transgenic mouse.
Author:	Sun, Qiang\|Zhang, Yingai\|Liu, Fang\|Zhao, Xiaohang\|Yang, Xiao
PMID:	18245957

34.
Journal:	J Mol Diagn. 2007 Sep;9(4):510-20.
Title:	Rapid identification of promoter hypermethylation in hepatocellular carcinoma by pyrosequencing of etiologically homogeneous sample pools.
Author:	Dejeux, Emelyne\|Audard, Virginie\|Cavard, Catherine\|Gut, Ivo Glynne\|Terris, Benoit\|Tost, Jorg
PMID:	17690210

35.
Journal:	Sichuan Da Xue Xue Bao Yi Xue Ban. 2007 Jan;38(1):49-52.
Title:	[The aberrant imprinting of insulin-like growth factor II and H19 in human hepatocellular carcinoma].
Author:	Wu, Jing\|Qin, Yang\|Li, Bo\|He, Wen-zhi\|Sun, Zhi-lin
PMID:	17294726

36.
Journal:	Genomics. 2008 May;91(5):443-50.
Title:	Hypomethylated and hypermethylated profiles of H19DMR are associated with the aberrant imprinting of IGF2 and H19 in human hepatocellular carcinoma.
Author:	Wu, Jing\|Qin, Yang\|Li, Bo\|He, Wen-zhi\|Sun, Zhi-lin
PMID:	18358696

37.
Journal:	World J Gastroenterol. 2008 Sep 21;14(35):5419-27.
Title:	Liver insulin-like growth factor 2 methylation in hepatitis C virus cirrhosis and further occurrence of hepatocellular carcinoma.
Author:	Couvert, Philippe\|Carrie, Alain\|Paries, Jacques\|Vaysse, Jenny\|Miroglio, Audrey\|Kerjean, Antoine\|Nahon, Pierre\|Chelly, Jamel\|Trinchet, Jean-Claude\|Beaugrand, Michel\|Ganne-Carrie, Nathalie
PMID:	18803353

38.
Journal:	Neoplasia. 2009 Sep;11(9):835-45.
Title:	Differential roles of insulin-like growth factor receptor- and insulin receptor-mediated signaling in the phenotypes of hepatocellular carcinoma cells.
Author:	Chen, Ya-Wen\|Boyartchuk, Victor\|Lewis, Brian C
PMID:	19724677

39.
Journal:	Int J Oncol. 2009 Oct;35(4):873-9.
Title:	Betulinic acid treatment promotes apoptosis in hepatoblastoma cells.
Author:	Eichenmuller, M\|von Schweinitz, D\|Kappler, R
PMID:	19724925

40.
Journal:	Viruses. 2009 Dec;1(3):852-72.
Title:	Molecular mechanisms underlying hepatocellular carcinoma.
Author:	Merle, Philippe\|Trepo, Christian
PMID:	21994573

41.
Journal:	J Hepatol. 2010 Apr;52(4):550-9.
Title:	IGF activation in a molecular subclass of hepatocellular carcinoma and pre-clinical efficacy of IGF-1R blockage.
Author:	Tovar, Victoria\|Alsinet, Clara\|Villanueva, Augusto\|Hoshida, Yujin\|Chiang, Derek Y\|Sole, Manel\|Thung, Swan\|Moyano, Susana\|Toffanin, Sara\|Minguez, Beatriz\|Cabellos, Laia\|Peix, Judit\|Schwartz, Myron\|Mazzaferro, Vincenzo\|Bruix, Jordi\|Llovet, Josep M
PMID:	20206398

42.
Journal:	Mol Cancer. 2010 Sep 22;9:256.
Title:	Salirasib inhibits the growth of hepatocarcinoma cell lines in vitro and tumor growth in vivo through ras and mTOR inhibition.
Author:	Charette, Nicolas\|De Saeger, Christine\|Lannoy, Valerie\|Horsmans, Yves\|Leclercq, Isabelle\|Starkel, Peter
PMID:	20860815

43.
Journal:	Minerva Gastroenterol Dietol. 2011 Sep;57(3):311-22.
Title:	Molecular signatures and prognosis of hepatocellular carcinoma.
Author:	Hoshida, Y
PMID:	21769080

44.
Journal:	J Hepatol. 2011 May;54(5):994-1001.
Title:	Overexpression of the IGF2-mRNA binding protein p62 in transgenic mice induces a steatotic phenotype.
Author:	Tybl, Elisabeth\|Shi, Fu-Dong\|Kessler, Sonja M\|Tierling, Sascha\|Walter, Jorn\|Bohle, Rainer M\|Wieland, Stefan\|Zhang, Jianying\|Tan, Eng M\|Kiemer, Alexandra K
PMID:	21145819

45.
Journal:	Lab Invest. 2011 Feb;91(2):262-72.
Title:	Epidermal growth factor induces cytokeratin 19 expression accompanied by increased growth abilities in human hepatocellular carcinoma.
Author:	Yoneda, Norihide\|Sato, Yasunori\|Kitao, Azusa\|Ikeda, Hiroko\|Sawada-Kitamura, Seiko\|Miyakoshi, Masami\|Harada, Kenichi\|Sasaki, Motoko\|Matsui, Osamu\|Nakanuma, Yasuni
PMID:	20856226

46.
Journal:	PLoS One. 2011 Mar 28;6(3):e17738.
Title:	Advanced computational biology methods identify molecular switches for malignancy in an EGF mouse model of liver cancer.
Author:	Stegmaier, Philip\|Voss, Nico\|Meier, Tatiana\|Kel, Alexander\|Wingender, Edgar\|Borlak, Juergen
PMID:	21464922

47.
Journal:	Mol Cell Biochem. 2012 Feb;361(1-2):337-43.
Title:	Igf2-derived intronic miR-483 promotes mouse hepatocellular carcinoma cell proliferation.
Author:	Ma, Ning\|Li, Fuyuan\|Li, Dan\|Hui, Yang\|Wang, Xidi\|Qiao, Yu\|Zhang, Yanfen\|Xiang, Ying\|Zhou, Jianying\|Zhou, Lingyun\|Zheng, Xiaofei\|Gao, Xu
PMID:	22052201

48.
Journal:	Mol Cancer. 2012 Mar 8;11:9.
Title:	IGFBP3 impedes aggressive growth of pediatric liver cancer and is epigenetically silenced in vascular invasive and metastatic tumors.
Author:	Regel, Ivonne\|Eichenmuller, Melanie\|Joppien, Saskia\|Liebl, Johanna\|Haberle, Beate\|Muller-Hocker, Josef\|Vollmar, Angelika\|von Schweinitz, Dietrich\|Kappler, Roland
PMID:	22401581

49.
Journal:	Clin Res Hepatol Gastroenterol. 2012 Aug;36(4):345-51.
Title:	Insulin-like growth factor 2 gene methylation in peripheral blood mononuclear cells of patients with hepatitis C related cirrhosis or hepatocellular carcinoma.
Author:	Couvert, Philippe\|Carrie, Alain\|Tezenas du Montcel, Sophie\|Vaysse, Jenny\|Sutton, Angela\|Barget, Nathalie\|Trinchet, Jean-Claude\|Beaugrand, Michel\|Ganne, Nathalie\|Giral, Philippe\|Chelly, Jamel
PMID:	22902352

50.
Journal:	Int J Clin Exp Med. 2012;5(4):296-305. Epub 2012 Aug 22.
Title:	Development of targeted therapy for a broad spectrum of cancers (pancreatic cancer, ovarian cancer, glioblastoma and HCC) mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory sequences.
Author:	Amit, Doron\|Hochberg, Abraham
PMID:	22993648

51.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2013 Feb 15;304(4):G328-36.
Title:	IGF2 mRNA binding protein p62/IMP2-2 in hepatocellular carcinoma: antiapoptotic action is independent of IGF2/PI3K signaling.
Author:	Kessler, Sonja M\|Pokorny, Juliane\|Zimmer, Vincent\|Laggai, Stephan\|Lammert, Frank\|Bohle, Rainer M\|Kiemer, Alexandra K
PMID:	23257922

52.
Journal:	Mol Med Rep. 2013 Mar;7(3):969-74.
Title:	Overexpression of GPC3 inhibits hepatocellular carcinoma cell proliferation and invasion through induction of apoptosis.
Author:	Pan, Zhijian\|Chen, Chunzhou\|Long, Haocheng\|Lei, Changjiang\|Tang, Gang\|Li, Lei\|Feng, Jiarui\|Chen, Feixiang
PMID:	23338845

53.
Journal:	Hepatology. 2013 Sep;58(3):1054-64.
Title:	Sirtuin-6-dependent genetic and epigenetic alterations are associated with poor clinical outcome in hepatocellular carcinoma patients.
Author:	Marquardt, Jens U\|Fischer, Kerstin\|Baus, Katharina\|Kashyap, Anubha\|Ma, Shengyun\|Krupp, Markus\|Linke, Matthias\|Teufel, Andreas\|Zechner, Ulrich\|Strand, Dennis\|Thorgeirsson, Snorri S\|Galle, Peter R\|Strand, Susanne
PMID:	23526469

54.
Journal:	Eur J Endocrinol. 2014 Mar 14;170(4):R147-57.
Title:	Management of endocrine disease: a clinical update on tumor-induced hypoglycemia.
Author:	Iglesias, Pedro\|Diez, Juan J
PMID:	24459236

55.
Journal:	Asian Pac J Cancer Prev. 2014;15(23):10085-9.
Title:	Induction of apoptosis by IGFBP3 overexpression in hepatocellular carcinoma cells.
Author:	Han, Jian-Jun\|Xue, De-Wen\|Han, Qiu-Rong\|Liang, Xiao-Hong\|Xie, Li\|Li, Sheng\|Wu, Hui-Yong\|Song, Bao
PMID:	25556430

56.
Journal:	PLoS One. 2014 Sep 17;9(9):e107149.
Title:	Fatty acid esters of phloridzin induce apoptosis of human liver cancer cells through altered gene expression.
Author:	Nair, Sandhya V G\|Ziaullah\|Rupasinghe, H P Vasantha
PMID:	25229655

57.
Journal:	Infect Agent Cancer. 2014 Aug 20;9:27.
Title:	The GH-IGF-SST system in hepatocellular carcinoma: biological and molecular pathogenetic mechanisms and therapeutic targets.
Author:	Pivonello, Claudia\|De Martino, Maria Cristina\|Negri, Mariarosaria\|Cuomo, Gaia\|Cariati, Federica\|Izzo, Francesco\|Colao, Annamaria\|Pivonello, Rosario
PMID:	25225571

58.
Journal:	Tissue Antigens. 2014 Sep;84(3):264-70.
Title:	Association of IGF1R polymorphisms with the development of HBV-related hepatocellular carcinoma.
Author:	Xie, H-Y\|Xing, C-Y\|Wei, B-J\|Xu, X\|Wu, J\|Chen, L-M\|Cao, G-Q\|Chen, H\|Chen, K-J\|Yin, S-Y\|Wu, L-M\|Zhou, L\|Zheng, S-S
PMID:	24758241

59.
Journal:	Chem Biol Interact. 2015 Dec 5;242:107-22.
Title:	Novel carbocyclic curcumin analog CUR3d modulates genes involved in multiple apoptosis pathways in human hepatocellular carcinoma cells.
Author:	Bhullar, Khushwant S\|Jha, Amitabh\|Rupasinghe, H P Vasantha
PMID:	26409325

60.
Journal:	FEBS Lett. 2015 Aug 4;589(17):2257-65.
Title:	miR-1275: A single microRNA that targets the three IGF2-mRNA-binding proteins hindering tumor growth in hepatocellular carcinoma.
Author:	Fawzy, Injie Omar\|Hamza, Mohammed Tarif\|Hosny, Karim Adel\|Esmat, Gamal\|El Tayebi, Hend Mohamed\|Abdelaziz, Ahmed Ihab
PMID:	26160756

61.
Journal:	Epigenomics. 2015;7(3):353-62.
Title:	Targeted deep DNA methylation analysis of circulating cell-free DNA in plasma using massively parallel semiconductor sequencing.
Author:	Vaca-Paniagua, Felipe\|Oliver, Javier\|Nogueira da Costa, Andre\|Merle, Philippe\|McKay, James\|Herceg, Zdenko\|Holmila, Reetta
PMID:	26077425

62.
Journal:	Cell Biol Int. 2015 Nov;39(11):1234-41.
Title:	Disruption of human vigilin impairs chromosome condensation and segregation.
Author:	Wei, Ling\|Xie, Xiaoyan\|Li, Junhong\|Li, Ran\|Shen, Wenyan\|Duan, Shuwang\|Zhao, Rongce\|Yang, Wenli\|Liu, Qiuying\|Fu, Qiang\|Qin, Yang
PMID:	26032007

63.
Journal:	Asian Pac J Cancer Prev. 2015;16(9):3667-71.
Title:	PU.1 Is Identified as a Novel Metastasis Suppressor in Hepatocellular Carcinoma Regulating the miR-615-5p/IGF2 Axis.
Author:	Song, Li-Jie\|Zhang, Wei-Jie\|Chang, Zhi-Wei\|Pan, Yan-Feng\|Zong, Hong\|Fan, Qing-Xia\|Wang, Liu-Xing
PMID:	25987019

64.
Journal:	Cell Death Dis. 2015 Mar 5;6:e1670.
Title:	MiR-216b is involved in pathogenesis and progression of hepatocellular carcinoma through HBx-miR-216b-IGF2BP2 signaling pathway.
Author:	Liu, F-y\|Zhou, S-j\|Deng, Y-l\|Zhang, Z-y\|Zhang, E-l\|Wu, Z-b\|Huang, Z-y\|Chen, X-p
PMID:	25741595

65.
Journal:	Hepatology. 2015 Mar;61(3):979-89.
Title:	Dysregulated serum response factor triggers formation of hepatocellular carcinoma.
Author:	Ohrnberger, Stefan\|Thavamani, Abhishek\|Braeuning, Albert\|Lipka, Daniel B\|Kirilov, Milen\|Geffers, Robert\|Autenrieth, Stella E\|Romer, Michael\|Zell, Andreas\|Bonin, Michael\|Schwarz, Michael\|Schutz, Gunther\|Schirmacher, Peter\|Plass, Christoph\|Longerich, Thomas
PMID:	25266280

66.
Journal:	Liver Int. 2015 Feb;35(2):608-19.
Title:	Hepatitis B virus X protein promotes P3 transcript expression of the insulin-like growth factor 2 gene via inducing hypomethylation of P3 promoter in hepatocellular carcinoma.
Author:	Tang, Shaohui\|Hu, Wei\|Hu, Jianjun\|Wu, Shenglan\|Li, Junfeng\|Luo, Yuhong\|Cao, Mingrong\|Zhou, Hongke\|Jiang, Xiangwu
PMID:	24423280

67.
Journal:	Cancer Sci. 2015 Aug;106(8):972-81.
Title:	Differential reactivation of fetal/neonatal genes in mouse liver tumors induced in cirrhotic and non-cirrhotic conditions.
Author:	Chen, Xi\|Yamamoto, Masahiro\|Fujii, Kiyonaga\|Nagahama, Yasuharu\|Ooshio, Takako\|Xin, Bing\|Okada, Yoko\|Furukawa, Hiroyuki\|Nishikawa, Yuji
PMID:	26011625

68.
Journal:	Oncotarget. 2016 Mar 1;7(9):9718-31.
Title:	The dual targeting of insulin and insulin-like growth factor 1 receptor enhances the mTOR inhibitor-mediated antitumor efficacy in hepatocellular carcinoma.
Author:	Pivonello, Claudia\|Negri, Mariarosaria\|De Martino, Maria Cristina\|Napolitano, Maria\|de Angelis, Cristina\|Provvisiero, Donatella Paola\|Cuomo, Gaia\|Auriemma, Renata Simona\|Simeoli, Chiara\|Izzo, Francesco\|Colao, Annamaria\|Hofland, Leo J\|Pivonello, Rosario
PMID:	26756219

69.
Journal:	J Neurol Surg A Cent Eur Neurosurg. 2016 May;77(3):247-57.
Title:	Hemoglobins, Hemorphins, and 11p15.5 Chromosomal Region in Cancer Biology and Immunity with Special Emphasis for Brain Tumors.
Author:	Altinoz, Meric Adil\|Elmaci, Ilhan\|Ince, Bahri\|Ozpinar, Aysel\|Sav, Aydin Murat
PMID:	26935297

70.
Journal:	Oncotarget. 2016 Aug 9;7(32):51349-51364.
Title:	Loss of insulin-like growth factor II imprinting is a hallmark associated with enhanced chemo/radiotherapy resistance in cancer stem cells.
Author:	Zhao, Xin\|Liu, Xiaoliang\|Wang, Guanjun\|Wen, Xue\|Zhang, Xiaoying\|Hoffman, Andrew R\|Li, Wei\|Hu, Ji-Fan\|Cui, Jiuwei
PMID:	27275535

71.
Journal:	Gastroenterology. 2016 Dec;151(6):1192-1205.
Title:	IGF2 Is Up-regulated by Epigenetic Mechanisms in Hepatocellular Carcinomas and Is an Actionable Oncogene Product in Experimental Models.
Author:	Martinez-Quetglas, Iris\|Pinyol, Roser\|Dauch, Daniel\|Torrecilla, Sara\|Tovar, Victoria\|Moeini, Agrin\|Alsinet, Clara\|Portela, Anna\|Rodriguez-Carunchio, Leonardo\|Sole, Manel\|Lujambio, Amaia\|Villanueva, Augusto\|Thung, Swan\|Esteller, Manel\|Zender, Lars\|Llovet,
PMID:	27614046

72.
Journal:	Nat Rev Gastroenterol Hepatol. 2016 Nov;13(11):625.
Title:	Liver cancer: IGF2 - an epigenetic oncodriver in HCC.
Author:	Thomas, Hugh
PMID:	27677717

73.
Journal:	J Biol Chem. 2016 Nov 11;291(46):24148-24159.
Title:	Prohibitin 1 Regulates the H19-Igf2 Axis and Proliferation in Hepatocytes.
Author:	Ramani, Komal\|Mavila, Nirmala\|Ko, Kwang Suk\|Mato, Jose M\|Lu, Shelly C
PMID:	27687727

74.
Journal:	Pediatr Blood Cancer. 2017 Mar;64(3).
Title:	Novel deletion in 11p15.5 imprinting center region 1 in a patient with Beckwith-Wiedemann syndrome provides insight into distal enhancer regulation and tumorigenesis.
Author:	Bachmann, Nadine\|Crazzolara, Roman\|Bohne, Florian\|Kotzot, Dieter\|Maurer, Kathrin\|Enklaar, Thorsten\|Prawitt, Dirk\|Bergmann, Carsten
PMID:	27650505

75.
Journal:	Diseases. 2017 Mar 8;5(1). pii: diseases5010011.
Title:	Targeting H19, an Imprinted Long Non-Coding RNA, in Hepatic Functions and Liver Diseases.
Author:	Pope, Chad\|Mishra, Shashank\|Russell, Joshua\|Zhou, Qingqing\|Zhong, Xiao-Bo
PMID:	28933364

76.
Journal:	Mol Cancer Ther. 2017 Oct;16(10):2223-2233.
Title:	The IGF1R/INSR Inhibitor BI 885578 Selectively Inhibits Growth of IGF2-Overexpressing Colorectal Cancer Tumors and Potentiates the Efficacy of Anti-VEGF Therapy.
Author:	Sanderson, Michael P\|Hofmann, Marco H\|Garin-Chesa, Pilar\|Schweifer, Norbert\|Wernitznig, Andreas\|Fischer, Stefan\|Jeschko, Astrid\|Meyer, Reiner\|Moll, Jurgen\|Pecina, Thomas\|Arnhof, Heribert\|Weyer-Czernilofsky, Ulrike\|Zahn, Stephan K\|Adolf, Gunther R\|Kraut, N
PMID:	28729397

77.
Journal:	Endocrinol Diabetes Metab Case Rep. 2017 May 16;2017. pii: EDM170004.
Title:	Pro-IGF2-induced hypoglycaemia associated with hepatocellular carcinoma.
Author:	van den Berg, S A A\|Krol, C G
PMID:	28567293

78.
Journal:	Oncogenesis. 2017 May 8;6(5):e328.
Title:	Regulation of miR-483-3p by the O-linked N-acetylglucosamine transferase links chemosensitivity to glucose metabolism in liver cancer cells.
Author:	Pepe, F\|Pagotto, S\|Soliman, S\|Rossi, C\|Lanuti, P\|Braconi, C\|Mariani-Costantini, R\|Visone, R\|Veronese, A
PMID:	28481368

79.
Journal:	EMBO Mol Med. 2017 Jun;9(6):741-749.
Title:	Hepatic stellate cells limit hepatocellular carcinoma progression through the orphan receptor endosialin.
Author:	Mogler, Carolin\|Konig, Courtney\|Wieland, Matthias\|Runge, Anja\|Besemfelder, Eva\|Komljenovic, Dorde\|Longerich, Thomas\|Schirmacher, Peter\|Augustin, Hellmut G
PMID:	28373218

80.
Journal:	Mol Carcinog. 2017 Jan;56(1):184-196.
Title:	beta-ionone modulates the expression of miRNAs and genes involved in the metastatic phenotype of microdissected persistent preneoplastic lesions in rats submitted to hepatocarcinogenesis.
Author:	Furtado, Kelly Silva\|de Oliveira Andrade, Fabia\|Campos, Adriana\|Rosim, Mariana Papaleo\|Vargas-Mendez, Ernesto\|Henriques, Aline\|De Conti, Aline\|Scolastici, Clarissa\|Barbisan, Luis Fernando\|Carvalho, Robson Francisco\|Moreno, Fernando Salvador
PMID:	27061051

81.
Journal:	Biochim Biophys Acta Gene Regul Mech. 2018 Feb;1861(2):117-124.
Title:	Epigenetic alterations contribute to promoter activity of imprinting gene IGF2.
Author:	Zheng, Qi-Fan\|Xu, Bin\|Wang, Hui-Min\|Ding, Li-Hong\|Liu, Jin-Yang\|Zhu, Ling-Yu\|Qiu, Huan\|Zhang, Li\|Ni, Guang-Yi\|Ye, Jing\|Gao, Shu-Bin\|Jin, Guang-Hui
PMID:	29413895

82.
Journal:	Int J Mol Sci. 2018 Apr 27;19(5). pii: ijms19051308.
Title:	Insulin-Like Growth Factor (IGF) System in Liver Diseases.
Author:	Adamek, Agnieszka\|Kasprzak, Aldona
PMID:	29702590

83.
Journal:	Oncotarget. 2018 Apr 3;9(25):17895-17905.
Title:	Tissue miRNA 483-3p expression predicts tumor recurrence after surgical resection in histologically advanced hepatocellular carcinomas.
Author:	Vasuri, Francesco\|Fittipaldi, Silvia\|De Pace, Vanessa\|Gramantieri, Laura\|Bertuzzo, Valentina\|Cescon, Matteo\|Pinna, Antonio D\|Fiorentino, Michelangelo\|D'Errico, Antonia\|Ravaioli, Matteo
PMID:	29707155

84.
Journal:	Biochim Biophys Acta Mol Basis Dis. 2018 May 30. pii: S0925-4439(18)30202-3.
Title:	Transgenic expression of the RNA binding protein IMP2 stabilizes miRNA targets in murine microsteatosis.
Author:	Dehghani Amirabad, Azim\|Ramasamy, Pathmanaban\|Wierz, Marina\|Nordstrom, Karl\|Kessler, Sonja M\|Schulz, Marcel H\|Simon, Martin
PMID:	29859241

85.
Journal:	Sci Rep. 2018 Aug 1;8(1):11570.
Title:	High-density single cell mRNA sequencing to characterize circulating tumor cells in hepatocellular carcinoma.
Author:	D'Avola, Delia\|Villacorta-Martin, Carlos\|Martins-Filho, Sebastiao N\|Craig, Amanda\|Labgaa, Ismail\|von Felden, Johann\|Kimaada, Allette\|Bonaccorso, Antoinette\|Tabrizian, Parissa\|Hartmann, Boris M\|Sebra, Robert\|Schwartz, Myron\|Villanueva, Augusto
PMID:	30068984

86.
Journal:	Mol Med Rep. 2018 Sep 27.
Title:	Identification of miRNA and mRNA expression profiles by PCR microarray in hepatitis B virusassociated hepatocellular carcinoma.
Author:	Cui, Xiong-Wei\|Qian, Zhi-Ling\|Li, Cong\|Cui, Shi-Chang
PMID:	30272372

87.
Journal:	Dis Markers. 2018 Sep 23;2018:8635329.
Title:	Investigating Pathogenic and Hepatocarcinogenic Mechanisms from Normal Liver to HCC by Constructing Genetic and Epigenetic Networks via Big Genetic and Epigenetic Data Mining and Genome-Wide NGS Data Identification.
Author:	Li, Cheng-Wei\|Chiu, Yu-Kai\|Chen, Bor-Sen
PMID:	30344796