Literatures

Primary Site >> Colorectal Cancer

Gene >> IGF2

1.
Journal:	Cancer Res. 1986 Dec;46(12 Pt 1):6169-73.
Title:	Enhanced levels of insulin-like growth factor messenger RNA in human colon carcinomas and liposarcomas.
Author:	Tricoli, J V\|Rall, L B\|Karakousis, C P\|Herrera, L\|Petrelli, N J\|Bell, G I\|Shows, T B
PMID:	3779638

2.
Journal:	Cancer Lett. 1987 Dec;38(1-2):223-30.
Title:	Presence of somatomedin receptors on primary human breast and colon carcinomas.
Author:	Pollak, M N\|Perdue, J F\|Margolese, R G\|Baer, K\|Richard, M
PMID:	2961436

3.
Journal:	Int J Cancer. 1987 Nov 15;40(5):646-52.
Title:	Simultaneous production of IGF-I and EGF competing growth factors by HT-29 human colon cancer line.
Author:	Culouscou, J M\|Remacle-Bonnet, M\|Garrouste, F\|Marvaldi, J\|Pommier, G
PMID:	3500134

4.
Journal:	J Cell Physiol. 1990 Jun;143(3):405-15.
Title:	Production of insulin-like growth factor II (IGF-II) and different forms of IGF-binding proteins by HT-29 human colon carcinoma cell line.
Author:	Culouscou, J M\|Remacle-Bonnet, M\|Garrouste, F\|Fantini, J\|Marvaldi, J\|Pommier, G
PMID:	1694180

5.
Journal:	Int J Cancer. 1990 Sep 15;46(3):405-10.
Title:	Abnormal expression and structural modification of the insulin-like growth-factor-II gene in human colorectal tumors.
Author:	Lambert, S\|Vivario, J\|Boniver, J\|Gol-Winkler, R
PMID:	1975564

6.
Journal:	Cancer Res. 1991 Jun 1;51(11):2813-9.
Title:	Purification of a colon cancer cell growth inhibitor and its identification as an insulin-like growth factor binding protein.
Author:	Culouscou, J M\|Shoyab, M
PMID:	1709585

7.
Journal:	Int J Cancer. 1991 Jul 30;48(6):826-30.
Title:	Tumor IGF-II content in a patient with a colon adenocarcinoma correlates with abnormal expression of the gene.
Author:	Lambert, S\|Collette, J\|Gillis, J\|Franchimont, P\|Desaive, C\|Gol-Winkler, R
PMID:	1713573

8.
Journal:	Int J Cancer. 1991 Mar 12;47(5):760-4.
Title:	Type-II insulin-like growth-factor receptor in conditioned medium from HT-29 human colon carcinoma cell line.
Author:	Garrouste, F\|Remacle-Bonnet, M\|Culouscou, J M\|Marvaldi, J\|Pommier, G
PMID:	1848538

9.
Journal:	Int J Cancer. 1992 Dec 2;52(6):910-7.
Title:	des-(1-3)-IGF-I, an insulin-like growth factor analog used to mimic a potential IGF-II autocrine loop, promotes the differentiation of human colon-carcinoma cells.
Author:	Remacle-Bonnet, M\|Garrouste, F\|el Atiq, F\|Roccabianca, M\|Marvaldi, J\|Pommier, G
PMID:	1281142

10.
Journal:	J Clin Endocrinol Metab. 1992 Aug;75(2):609-16.
Title:	Expression of type I, but not type II insulin-like growth factor receptor on both undifferentiated and differentiated HT29 human colon carcinoma cell line.
Author:	Remacle-Bonnet, M M\|Culouscou, J M\|Garrouste, F L\|Rabenandrasana, C\|Marvaldi, J L\|Pommier, G J
PMID:	1322432

11.
Journal:	Int J Cancer. 1992 Sep 30;52(3):404-8.
Title:	Insulin-like growth factor II in two human colon-carcinoma cell lines: gene structure and expression, and protein secretion.
Author:	Lambert, S\|Carlisi, A\|Collette, J\|Franchimont, P\|Gol-Winkler, R
PMID:	1399116

12.
Journal:	Semin Liver Dis. 1992 Aug;12(3):265-78.
Title:	Cellular and molecular mechanisms of hepatocarcinogenesis.
Author:	Rogler, C E\|Chisari, F V
PMID:	1439879

13.
Journal:	Oncology. 1992;49(3):209-14.
Title:	Pattern of growth factor, proto-oncogene and carcinoembryonic antigen gene expression in human colorectal carcinoma cell lines.
Author:	La Rocca, R V\|Park, J G\|Danesi, R\|Del Tacca, M\|Steinberg, S M\|Gazdar, A F
PMID:	1495747

14.
Journal:	Br J Cancer. 1992 Mar;65(3):341-6.
Title:	Growth regulation and co-stimulation of human colorectal cancer cell lines by insulin-like growth factor I, II and transforming growth factor alpha.
Author:	Lahm, H\|Suardet, L\|Laurent, P L\|Fischer, J R\|Ceyhan, A\|Givel, J C\|Odartchenko, N
PMID:	1558785

15.
Journal:	Int J Cancer. 1994 May 15;57(4):491-7.
Title:	Alterations in serum levels of insulin-like growth factors and insulin-like growth-factor-binding proteins in patients with colorectal cancer.
Author:	el Atiq, F\|Garrouste, F\|Remacle-Bonnet, M\|Sastre, B\|Pommier, G
PMID:	7514152

16.
Journal:	Am J Physiol. 1994 Oct;267(4 Pt 1):G608-17.
Title:	Expression of IGF-II and IGF-binding proteins by colon cancer cells in relation to growth response to IGFs.
Author:	Singh, P\|Dai, B\|Yallampalli, C\|Xu, Z
PMID:	7524348

17.
Journal:	Cancer Res. 1994 Dec 15;54(24):6563-70.
Title:	Episomal expression of sense and antisense insulin-like growth factor (IGF)-binding protein-4 complementary DNA alters the mitogenic response of a human colon cancer cell line (HT-29) by mechanisms that are independent of and dependent upon IGF-I.
Author:	Singh, P\|Dai, B\|Dhruva, B\|Widen, S G
PMID:	7527300

18.
Journal:	Cell Growth Differ. 1994 Oct;5(10):1085-91.
Title:	Expression of insulin-like growth factor (IGF)-II and IGF-I receptor during proliferation and differentiation of CaCo-2 human colon carcinoma cells.
Author:	Zarrilli, R\|Pignata, S\|Romano, M\|Gravina, A\|Casola, S\|Bruni, C B\|Acquaviva, A M
PMID:	7848910

19.
Journal:	Int J Cancer. 1994 Aug 1;58(3):452-9.
Title:	Blockade of the insulin-like growth-factor-I receptor inhibits growth of human colorectal cancer cells: evidence of a functional IGF-II-mediated autocrine loop.
Author:	Lahm, H\|Amstad, P\|Wyniger, J\|Yilmaz, A\|Fischer, J R\|Schreyer, M\|Givel, J C
PMID:	8050827

20.
Journal:	Mol Cell Endocrinol. 1994 May;101(1-2):141-50.
Title:	Human colon carcinoma cells (CaCo-2) synthesize IGF-II and express IGF-I receptors and IGF-II/M6P receptors.
Author:	Hoeflich, A\|Yang, Y\|Kessler, U\|Heinz-Erian, P\|Kolb, H\|Kiess, W
PMID:	9397946

21.
Journal:	Exp Cell Res. 1995 Feb;216(2):342-51.
Title:	Constitutive or inducible overexpression of the IGF-2 gene in cells of a human colon carcinoma cell line.
Author:	Lamonerie, T\|Lavialle, C\|de Galle, B\|Binoux, M\|Brison, O
PMID:	7531153

22.
Journal:	J Clin Invest. 1995 Jul;96(1):192-200.
Title:	Cell polarity of the insulin-like growth factor system in human intestinal epithelial cells. Unique apical sorting of insulin-like growth factor binding protein-6 in differentiated human colon cancer cells.
Author:	Remacle-Bonnet, M\|Garrouste, F\|el Atiq, F\|Marvaldi, J\|Pommier, G
PMID:	7542277

23.
Journal:	J Am Coll Surg. 1995 Aug;181(2):145-54.
Title:	Insulin-like growth factor-II expression in carcinoma in colon cell lines: implications for autocrine actions.
Author:	Guo, Y S\|Jin, G F\|Townsend, C M Jr\|Zhang, T\|Sheng, H M\|Beauchamp, R D\|Thompson, J C
PMID:	7627387

24.
Journal:	Int J Cancer. 1995 May 16;61(4):587-92.
Title:	IGF-2 autocrine stimulation in tumorigenic clones of a human colon-carcinoma cell line.
Author:	Lamonerie, T\|Lavialle, C\|Haddada, H\|Brison, O
PMID:	7759165

25.
Journal:	Endocrinology. 1996 May;137(5):1764-74.
Title:	Proliferation and differentiation of a human colon cancer cell line (CaCo2) is associated with significant changes in the expression and secretion of insulin-like growth factor (IGF) IGF-II and IGF binding protein-4: role of IGF-II.
Author:	Singh, P\|Dai, B\|Yallampalli, U\|Lu, X\|Schroy, P C
PMID:	8612513

26.
Journal:	J Biol Chem. 1996 Apr 5;271(14):8108-14.
Title:	Constitutive insulin-like growth factor-II expression interferes with the enterocyte-like differentiation of CaCo-2 cells.
Author:	Zarrilli, R\|Romano, M\|Pignata, S\|Casola, S\|Bruni, C B\|Acquaviva, A M
PMID:	8626497

27.
Journal:	Biochem Biophys Res Commun. 1996 Mar 18;220(2):334-40.
Title:	Differential effect of interleukin-4 and transforming growth factor beta 1 on expression of proto-oncogenes and autocrine insulin-like growth factor II in colorectal carcinoma cells.
Author:	Lahm, H\|Amstad, P\|Yilmaz, A\|Fischer, J R\|Givel, J C\|Odartchenko, N\|Sordat, B
PMID:	8645306

28.
Journal:	Eur J Endocrinol. 1996 Jul;135(1):49-59.
Title:	Coordinate expression of insulin-like growth factor II (IGF-II) and IGF-II/mannose-6-phosphate receptor mRNA and stable expression of IGF-I receptor mRNA during differentiation of human colon carcinoma cells (Caco-2).
Author:	Hoeflich, A\|Yang, Y\|Rascher, W\|Blum, W F\|Huber, S\|Koepf, G\|Kolb, H J\|Kiess, W
PMID:	8765974

29.
Journal:	Cancer Lett. 1996 Oct 1;107(1):105-8.
Title:	Relaxation of imprinting of the insulin-like growth factor II gene in colorectal cancer.
Author:	Kinouchi, Y\|Hiwatashi, N\|Higashioka, S\|Nagashima, F\|Chida, M\|Toyota, T
PMID:	8913273

30.
Journal:	Cancer Res. 1996 Dec 1;56(23):5356-9.
Title:	IGF2 but not H19 shows loss of imprinting in human glioma.
Author:	Uyeno, S\|Aoki, Y\|Nata, M\|Sagisaka, K\|Kayama, T\|Yoshimoto, T\|Ono, T
PMID:	8968084

31.
Journal:	J Clin Endocrinol Metab. 1997 Jun;82(6):1917-22.
Title:	Coexpression of stromelysin-3 and insulin-like growth factor II in tumors of ectodermal, mesodermal, and endodermal origin: indicator of a fetal cell phenotype.
Author:	Singer, C F\|Rasmussen, A\|Lippman, M E\|Cullen, K J
PMID:	9177406

32.
Journal:	Br J Cancer. 1997;76(1):60-6.
Title:	Insulin-like growth factors and their binding proteins in human colonocytes: preferential degradation of insulin-like growth factor binding protein 2 in colonic cancers.
Author:	Michell, N P\|Langman, M J\|Eggo, M C
PMID:	9218734

33.
Journal:	Cancer Res. 1997 Aug 15;57(16):3370-4.
Title:	Association between CpG island methylation and microsatellite instability in colorectal cancer.
Author:	Ahuja, N\|Mohan, A L\|Li, Q\|Stolker, J M\|Herman, J G\|Hamilton, S R\|Baylin, S B\|Issa, J P
PMID:	9269998

34.
Journal:	Int J Cancer. 1997 Sep 4;72(5):835-43.
Title:	Surface-bound plasmin induces selective proteolysis of insulin-like-growth-factor (IGF)-binding protein-4 (IGFBP-4) and promotes autocrine IGF-II bio-availability in human colon-carcinoma cells.
Author:	Remacle-Bonnet, M M\|Garrouste, F L\|Pommier, G J
PMID:	9311602

35.
Journal:	Int J Cancer. 1997 Dec 10;73(6):880-4.
Title:	Effect of aspirin on cell proliferation and differentiation of colon adenocarcinoma Caco-2 cells.
Author:	Ricchi, P\|Pignata, S\|Di Popolo, A\|Memoli, A\|Apicella, A\|Zarrilli, R\|Acquaviva, A M
PMID:	9399670

36.
Journal:	Cancer. 1998 Apr 15;82(8):1585-92.
Title:	The role of glucagon administration in the diagnosis and treatment of patients with tumor hypoglycemia.
Author:	Hoff, A O\|Vassilopoulou-Sellin, R
PMID:	9554538

37.
Journal:	Oncology. 1998 May-Jun;55(3):242-8.
Title:	Expression of insulin-like growth factor-2 can predict the prognosis of human colorectal cancer patients: correlation with tumor progression, proliferative activity and survival.
Author:	Kawamoto, K\|Onodera, H\|Kondo, S\|Kan, S\|Ikeuchi, D\|Maetani, S\|Imamura, M
PMID:	9560057

38.
Journal:	Gastroenterology. 1998 Jun;114(6):1221-9.
Title:	Differential activation of IGF-II promoters P3 and P4 in Caco-2 cells during growth and differentiation.
Author:	Singh, P\|Dai, B\|Given, R L\|Lu, X\|Holthuizen, P E
PMID:	9609759

39.
Journal:	J Cell Biol. 1998 Jun 15;141(6):1407-14.
Title:	OCI-5/GPC3, a glypican encoded by a gene that is mutated in the Simpson-Golabi-Behmel overgrowth syndrome, induces apoptosis in a cell line-specific manner.
Author:	Gonzalez, A D\|Kaya, M\|Shi, W\|Song, H\|Testa, J R\|Penn, L Z\|Filmus, J
PMID:	9628896

40.
Journal:	Nat Med. 1998 Nov;4(11):1276-80.
Title:	Loss of imprinting in normal tissue of colorectal cancer patients with microsatellite instability.
Author:	Cui, H\|Horon, I L\|Ohlsson, R\|Hamilton, S R\|Feinberg, A P
PMID:	9809551

41.
Journal:	Cancer Res. 1998 Nov 1;58(21):4802-4.
Title:	Sequence alterations of insulin-like growth factor binding protein 3 in neoplastic and normal gastrointestinal tissues.
Author:	Zou, T\|Fleisher, A S\|Kong, D\|Yin, J\|Souza, R F\|Wang, S\|Smolinski, K N\|Abraham, J M\|Meltzer, S J
PMID:	9809981

42.
Journal:	Cancer Res. 1998 Dec 1;58(23):5489-94.
Title:	Aging and DNA methylation in colorectal mucosa and cancer.
Author:	Ahuja, N\|Li, Q\|Mohan, A L\|Baylin, S B\|Issa, J P
PMID:	9850084

43.
Journal:	Cancer. 1999 Jan 1;85(1):18-25.
Title:	Possible paracrine mechanism of insulin-like growth factor-2 in the development of liver metastases from colorectal carcinoma.
Author:	Kawamoto, K\|Onodera, H\|Kan, S\|Kondo, S\|Imamura, M
PMID:	9921969

44.
Journal:	J Natl Cancer Inst. 1999 Apr 7;91(7):620-5.
Title:	Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3.
Author:	Ma, J\|Pollak, M N\|Giovannucci, E\|Chan, J M\|Tao, Y\|Hennekens, C H\|Stampfer, M J
PMID:	10203281

45.
Journal:	Horm Metab Res. 1999 Feb-Mar;31(2-3):148-54.
Title:	IGF-II in primary human colorectal tumors: peptide level, activated promoters, parental imprinting and gene rearrangement.
Author:	Winkler, R\|Delacroix, L\|Bensbaho, K\|Lambert, S\|Collette, J\|Hodzic, D
PMID:	10226796

46.
Journal:	J Pathol. 1999 Apr;187(5):518-22.
Title:	Analysis of IGF2 gene imprinting in breast and colorectal cancer by allele specific-PCR.
Author:	Yun, K\|Soejima, H\|Merrie, A E\|McCall, J L\|Reeve, A E
PMID:	10398115

47.
Journal:	Int J Cancer. 1999 Sep 24;83(1):15-7.
Title:	IGF-I and IGF-II in relation to colorectal cancer.
Author:	Manousos, O\|Souglakos, J\|Bosetti, C\|Tzonou, A\|Chatzidakis, V\|Trichopoulos, D\|Adami, H O\|Mantzoros, C
PMID:	10449601

48.
Journal:	Trends Endocrinol Metab. 1999 Dec;10(10):383-391.
Title:	Antagonistic Analogs of Growth Hormone-releasing Hormone: New Potential Antitumor Agents.
Author:	Schally\|Varga
PMID:	10542394

49.
Journal:	Zhonghua Wai Ke Za Zhi. 1999 Dec;37(12):718-20, 43.
Title:	[Relationship between insulin-like growth factor II and prognosis of colorectal cancer].
Author:	Xu, Z\|Liu, F\|Qi, X\|Li, J
PMID:	11829934

50.
Journal:	Cancer Res. 2000 Feb 15;60(4):1070-6.
Title:	Insulin-like growth factor II supply modifies growth of intestinal adenoma in Apc(Min/+) mice.
Author:	Hassan, A B\|Howell, J A
PMID:	10706126

51.
Journal:	Br J Cancer. 2000 May;82(10):1724-31.
Title:	Antagonists of growth hormone-releasing hormone (GH-RH) inhibit IGF-II production and growth of HT-29 human colon cancers.
Author:	Szepeshazi, K\|Schally, A V\|Groot, K\|Armatis, P\|Halmos, G\|Herbert, F\|Szende, B\|Varga, J L\|Zarandi, M
PMID:	10817510

52.
Journal:	Int J Oncol. 2000 Aug;17(2):317-22.
Title:	Multipoint imprinting analysis in sporadic colorectal cancers with and without microsatellite instability.
Author:	Nishihara, S\|Hayashida, T\|Mitsuya, K\|Schulz, T C\|Ikeguchi, M\|Kaibara, N\|Oshimura, M
PMID:	10891541

53.
Journal:	Histol Histopathol. 2000 Jul;15(3):835-42.
Title:	Aging, methylation and cancer.
Author:	Ahuja, N\|Issa, J P
PMID:	10963127

54.
Journal:	J Clin Endocrinol Metab. 2000 Sep;85(9):3402-8.
Title:	Circulating insulin-like growth factor II and colorectal adenomas.
Author:	Renehan, A G\|Painter, J E\|O'Halloran, D\|Atkin, W S\|Potten, C S\|O'Dwyer, S T\|Shalet, S M
PMID:	10999841

55.
Journal:	Br J Cancer. 2000 Nov;83(10):1344-50.
Title:	Elevated serum insulin-like growth factor (IGF)-II and IGF binding protein-2 in patients with colorectal cancer.
Author:	Renehan, A G\|Jones, J\|Potten, C S\|Shalet, S M\|O'Dwyer, S T
PMID:	11044360

56.
Journal:	Oncology. 2000 Sep;59(3):210-6.
Title:	Analysis of genomic imprinting of insulin-like growth factor 2 in colorectal cancer.
Author:	Takano, Y\|Shiota, G\|Kawasaki, H
PMID:	11053988

57.
Journal:	Oncogene. 2000 Nov 16;19(48):5517-24.
Title:	IGF-II/IGF-I receptor pathway up-regulates COX-2 mRNA expression and PGE2 synthesis in Caco-2 human colon carcinoma cells.
Author:	Di Popolo, A\|Memoli, A\|Apicella, A\|Tuccillo, C\|di Palma, A\|Ricchi, P\|Acquaviva, A M\|Zarrilli, R
PMID:	11114729

58.
Journal:	Proc Natl Acad Sci U S A. 2001 Jan 16;98(2):591-6. Epub 2000 Dec 19.
Title:	Loss of imprinting of the insulin-like growth factor II gene occurs by biallelic methylation in a core region of H19-associated CTCF-binding sites in colorectal cancer.
Author:	Nakagawa, H\|Chadwick, R B\|Peltomaki, P\|Plass, C\|Nakamura, Y\|de La Chapelle, A
PMID:	11120891

59.
Journal:	Mol Cell Endocrinol. 2001 Mar 28;174(1-2):121-7.
Title:	Insulin-like growth factor (IGF)-binding protein-6 inhibits IGF-II-induced but not basal proliferation and adhesion of LIM 1215 colon cancer cells.
Author:	Leng, S L\|Leeding, K S\|Whitehead, R H\|Bach, L A
PMID:	11306178

60.
Journal:	Clin Endocrinol (Oxf). 2001 Apr;54(4):499-508.
Title:	Increased levels of insulin-like growth factor binding protein-2 in sera and tumours from patients with colonic neoplasia with and without acromegaly.
Author:	Miraki-Moud, F\|Jenkins, P J\|Fairclough, P D\|Jordan, S\|Bustin, S A\|Jones, A M\|Lowe, D G\|Monson, J P\|Grossman, A B\|Besser, G M\|Camacho-Hubner, C
PMID:	11318786

61.
Journal:	Oncology. 2001;60(3):268-73.
Title:	Loss of imprinting of long QT intronic transcript 1 in colorectal cancer.
Author:	Tanaka, K\|Shiota, G\|Meguro, M\|Mitsuya, K\|Oshimura, M\|Kawasaki, H
PMID:	11340379

62.
Journal:	Carcinogenesis. 2001 Oct;22(10):1625-31.
Title:	Insulin-like growth factor-II renders LIM 2405 human colon cancer cells resistant to butyrate-induced apoptosis: a potential mechanism for colon cancer cell survival in vivo.
Author:	Leng, S L\|Leeding, K S\|Gibson, P R\|Bach, L A
PMID:	11577001

63.
Journal:	Mol Cell Endocrinol. 2001 Oct 25;183(1-2):141-9.
Title:	Synthetic low-calcaemic vitamin D(3) analogues inhibit secretion of insulin-like growth factor II and stimulate production of insulin-like growth factor-binding protein-6 in conjunction with growth suppression of HT-29 colon cancer cells.
Author:	Oh, Y S\|Kim, E J\|Schaffer, B S\|Kang, Y H\|Binderup, L\|MacDonald, R G\|Park, J H
PMID:	11604234

64.
Journal:	Hum Mol Genet. 2001 Nov 1;10(23):2619-26.
Title:	Large scale mapping of methylcytosines in CTCF-binding sites in the human H19 promoter and aberrant hypomethylation in human bladder cancer.
Author:	Takai, D\|Gonzales, F A\|Tsai, Y C\|Thayer, M J\|Jones, P A
PMID:	11726548

65.
Journal:	Br J Cancer. 2001 Nov 30;85(11):1695-9.
Title:	IGF-1, IGF-2 and IGFBP-3 in prediagnostic serum: association with colorectal cancer in a cohort of Chinese men in Shanghai.
Author:	Probst-Hensch, N M\|Yuan, J M\|Stanczyk, F Z\|Gao, Y T\|Ross, R K\|Yu, M C
PMID:	11742490

66.
Journal:	J Cell Physiol. 2002 Jan;190(1):92-100.
Title:	Inhibition of Caco-2 cell proliferation by all-trans retinoic acid: role of insulin-like growth factor binding protein-6.
Author:	Kim, Eun J\|Kang, Young-Hee\|Schaffer, Beverly S\|Bach, Leon A\|MacDonald, Richard G\|Park, Jung H Y
PMID:	11807815

67.
Journal:	Cancer. 2002 Feb 1;94(3):647-57.
Title:	Relevance of biologic markers in colorectal carcinoma: a comparative study of a broad panel.
Author:	Barozzi, Chiara\|Ravaioli, Matteo\|D'Errico, Antonia\|Grazi, Gian Luca\|Poggioli, Gilberto\|Cavrini, Giulia\|Mazziotti, Alighieri\|Grigioni, Walter Franco
PMID:	11857296

68.
Journal:	Int J Cancer. 2002 Apr 10;98(5):665-73.
Title:	Insulin-like growth factor-I has a biphasic effect on colon carcinoma cells through transient inactivation of forkhead1, initially mitogenic, then mediating growth arrest and differentiation.
Author:	Ewton, Daina Z\|Kansra, Sanjay\|Lim, Seunghwan\|Friedman, Eileen
PMID:	11920634

69.
Journal:	Nature. 2002 Apr 4;416(6880):552-6.
Title:	DNMT1 and DNMT3b cooperate to silence genes in human cancer cells.
Author:	Rhee, Ina\|Bachman, Kurtis E\|Park, Ben Ho\|Jair, Kam-Wing\|Yen, Ray-Whay Chiu\|Schuebel, Kornel E\|Cui, Hengmi\|Feinberg, Andrew P\|Lengauer, Christoph\|Kinzler, Kenneth W\|Baylin, Stephen B\|Vogelstein, Bert
PMID:	11932749

70.
Journal:	Cancer Res. 2002 May 15;62(10):2923-8.
Title:	Development of a highly specialized cDNA array for the study and diagnosis of epithelial ovarian cancer.
Author:	Sawiris, G Peter\|Sherman-Baust, Cheryl A\|Becker, Kevin G\|Cheadle, Chris\|Teichberg, Diane\|Morin, Patrice J
PMID:	12019173

71.
Journal:	J Gastroenterol Hepatol. 2002 May;17(5):563-70.
Title:	Decreased production of insulin-like growth factor-binding protein (IGFBP)-6 by transfection of colon cancer cells with an antisense IGFBP-6 cDNA construct leads to stimulation of cell proliferation.
Author:	Kim, Eun J\|Schaffer, Beverly S\|Kang, Young-hee\|Macdonald, Richard G\|Park, Jung Hy
PMID:	12084030

72.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2002 Aug;283(2):G357-67.
Title:	Trans-10,cis-12-conjugated linoleic acid inhibits Caco-2 colon cancer cell growth.
Author:	Kim, Eun J\|Holthuizen, P Elly\|Park, Hyun S\|Ha, Yeong L\|Jung, Kyeong C\|Park, Jung H Y
PMID:	12121883

73.
Journal:	Cancer Epidemiol Biomarkers Prev. 2002 Sep;11(9):901-5.
Title:	Insulin-like growth factor II and colorectal cancer risk in women.
Author:	Hunt, Kelly J\|Toniolo, Paolo\|Akhmedkhanov, Arslan\|Lukanova, Annekatrin\|Dechaud, Henri\|Rinaldi, Sabina\|Zeleniuch-Jacquotte, Anne\|Shore, Roy E\|Riboli, Elio\|Kaaks, Rudolf
PMID:	12223436

74.
Journal:	Gastroenterology. 2002 Oct;123(4):1191-204.
Title:	Effects of genetic blockade of the insulin-like growth factor receptor in human colon cancer cell lines.
Author:	Adachi, Yasushi\|Lee, Choon-Taek\|Coffee, Keith\|Yamagata, Noboru\|Ohm, Joyce E\|Park, Kyung-Ho\|Dikov, Mikhail M\|Nadaf, Sorena R\|Arteaga, Carlos L\|Carbone, David P
PMID:	12360481

75.
Journal:	Cancer. 2002 Nov 15;95(10):2086-95.
Title:	Overexpression of the insulin-like growth factor I receptor in human colon carcinomas.
Author:	Weber, Matthias M\|Fottner, Christian\|Liu, Sun Bin\|Jung, M Christina\|Engelhardt, Dieter\|Baretton, Gustavo B
PMID:	12412161

76.
Journal:	Cancer Res. 2002 Nov 15;62(22):6442-6.
Title:	Loss of imprinting in colorectal cancer linked to hypomethylation of H19 and IGF2.
Author:	Cui, Hengmi\|Onyango, Patrick\|Brandenburg, Sheri\|Wu, Yiqian\|Hsieh, Chih-Lin\|Feinberg, Andrew P
PMID:	12438232

77.
Journal:	Ai Zheng. 2002 Nov;21(11):1226-30.
Title:	[Expression and clinical significance of IGF-II mRNA and bcl-2 protein in colorectal adenocarcinomas].
Author:	Zhang, Ming-sheng\|Yuan, Hong-yin\|Xiong, Bin\|Deng, Qin\|Tang, Zhi-jiao\|Xia, Dong
PMID:	12526221

78.
Journal:	Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2003 Feb;20(1):31-4.
Title:	[The expression and imprinting status of insulin-like growth factor 2 gene in colorectal cancer].
Author:	Zhang, Feng-rui\|He, Xiao-bing\|Yang, Yu-hua\|Xie, Wei
PMID:	12579496

79.
Journal:	Science. 2003 Mar 14;299(5613):1753-5.
Title:	Loss of IGF2 imprinting: a potential marker of colorectal cancer risk.
Author:	Cui, Hengmi\|Cruz-Correa, Marcia\|Giardiello, Francis M\|Hutcheon, David F\|Kafonek, David R\|Brandenburg, Sheri\|Wu, Yiqian\|He, Xiaobing\|Powe, Neil R\|Feinberg, Andrew P
PMID:	12637750

80.
Journal:	Virchows Arch. 2003 Aug;443(2):139-45. Epub 2003 Jul 5.
Title:	IGF-1R, IGF-1 and IGF-2 expression as potential prognostic and predictive markers in colorectal-cancer.
Author:	Peters, Gerrit\|Gongoll, Silvia\|Langner, Cord\|Mengel, Michael\|Piso, Pompiliu\|Klempnauer, Jurgen\|Ruschoff, Josef\|Kreipe, Hans\|von Wasielewski, Reinhard
PMID:	12845531

81.
Journal:	J Nutr. 2003 Aug;133(8):2675-81.
Title:	Conjugated linoleic acid downregulates insulin-like growth factor-I receptor levels in HT-29 human colon cancer cells.
Author:	Kim, Eun Ji\|Kang, Il-Jun\|Cho, Han Jin\|Kim, Woo Kyoung\|Ha, Yeong-Lae\|Park, Jung Han Yoon
PMID:	12888657

82.
Journal:	Cancer Res. 2003 Oct 15;63(20):6726-34.
Title:	Inhibition of angiotensin II activity enhanced the antitumor effect of cyclooxygenase-2 inhibitors via insulin-like growth factor I receptor pathway.
Author:	Yasumaru, Masakazu\|Tsuji, Shingo\|Tsujii, Masahiko\|Irie, Takanobu\|Komori, Masato\|Kimura, Arata\|Nishida, Tsutomu\|Kakiuchi, Yoshimi\|Kawai, Naoki\|Murata, Hiroaki\|Horimoto, Masayoshi\|Sasaki, Yutaka\|Hayashi, Norio\|Kawano, Sunao\|Hori, Masatsugu
PMID:	14583467

83.
Journal:	J Med Food. 2003 Fall;6(3):193-9.
Title:	trans-10, cis-12 conjugated linoleic acid reduces insulin-like growth factor-II secretion in HT-29 human colon cancer cells.
Author:	Cho, Han Jin\|Lee, Hyun Sook\|Chung, Cha-Kwon\|Kang, Young-Hee\|Ha, Yeong Lae\|Park, Hyun-Suh\|Park, Jung Han Yoon
PMID:	14585185

84.
Journal:	J Endocrinol. 2003 Dec;179(3):405-15.
Title:	Interleukin-1beta (IL-1beta) and IL-6 modulate insulin-like growth factor-binding protein (IGFBP) secretion in colon cancer epithelial (Caco-2) cells.
Author:	Street, M E\|Miraki-Moud, F\|Sanderson, I R\|Savage, M O\|Giovannelli, G\|Bernasconi, S\|Camacho-Hubner, C
PMID:	14656210

85.
Journal:	Cancer Res. 2004 Mar 1;64(5):1600-3.
Title:	Insulin-like growth factor (IGF)-binding protein-4 inhibits colony formation of colorectal cancer cells by IGF-independent mechanisms.
Author:	Diehl, Daniela\|Hoeflich, Andreas\|Wolf, Eckhard\|Lahm, Harald
PMID:	14996716

86.
Journal:	J Natl Cancer Inst. 2004 Mar 3;96(5):407-10.
Title:	Loss of insulin-like growth factor-II imprinting and the presence of screen-detected colorectal adenomas in women.
Author:	Woodson, Karen\|Flood, Andrew\|Green, Lisa\|Tangrea, Joseph A\|Hanson, Jeffrey\|Cash, Brooks\|Schatzkin, Arthur\|Schoenfeld, Phillip
PMID:	14996863

87.
Journal:	Gastroenterology. 2004 Apr;126(4):964-70.
Title:	Loss of imprinting of insulin growth factor II gene: a potential heritable biomarker for colon neoplasia predisposition.
Author:	Cruz-Correa, Marcia\|Cui, Hengmi\|Giardiello, Francis M\|Powe, Neil R\|Hylind, Linda\|Robinson, Angela\|Hutcheon, David F\|Kafonek, David R\|Brandenburg, Sheri\|Wu, Yiqian\|He, Xiaobing\|Feinberg, Andrew P
PMID:	15057734

88.
Journal:	Gastroenterology. 2004 Apr;126(4):1190-3.
Title:	IGF2 loss of imprinting: a potential heritable risk factor for colorectal cancer.
Author:	Jirtle, Randy L
PMID:	15057757

89.
Journal:	Biochem Biophys Res Commun. 2004 Jun 11;318(4):916-9.
Title:	Oncofetal splice-pattern of the human H19 gene.
Author:	Matouk, Imad\|Ayesh, Basim\|Schneider, Tamar\|Ayesh, Suhail\|Ohana, Patricia\|de-Groot, Nathan\|Hochberg, Abraham\|Galun, Eithan
PMID:	15147959

90.
Journal:	Tumour Biol. 2004 Jan-Apr;25(1-2):62-8.
Title:	Differential expression patterns of the insulin-like growth factor 2 gene in human colorectal cancer.
Author:	Li, Shu-Rui\|Ng, Chung Fai Jeremy\|Banerjea, Ayan\|Ahmed, Shafi\|Hands, Rebecca\|Powar, Michael\|Ogunkolade, William\|Dorudi, Sina\|Bustin, Stephen A
PMID:	15192314

91.
Journal:	Int J Oncol. 2004 Nov;25(5):1273-8.
Title:	Allele-specific methylation analysis on upstream promoter region of H19 by methylation-specific PCR with confronting two-pair primers.
Author:	Sasamoto, Hiromi\|Nagasaka, Takeshi\|Notohara, Kenji\|Ozaki, Kazuhide\|Isozaki, Hiroshi\|Tanaka, Noriaki\|Matsubara, Nagahide
PMID:	15492815

92.
Journal:	J Mol Endocrinol. 2004 Oct;33(2):377-86.
Title:	Contributions of the N- and C-terminal domains of IGF binding protein-6 to IGF binding.
Author:	Headey, Stephen J\|Leeding, Kerri S\|Norton, Raymond S\|Bach, Leon A
PMID:	15525596

93.
Journal:	Clin Cancer Res. 2004 Dec 1;10(23):7950-7.
Title:	Interplay of insulin-like growth factor-II, insulin-like growth factor-I, insulin-like growth factor-I receptor, COX-2, and matrix metalloproteinase-7, play key roles in the early stage of colorectal carcinogenesis.
Author:	Nosho, Katsuhiko\|Yamamoto, Hiroyuki\|Taniguchi, Hiroaki\|Adachi, Yasushi\|Yoshida, Yukinari\|Arimura, Yoshiaki\|Endo, Takao\|Hinoda, Yuji\|Imai, Kohzoh
PMID:	15585629

94.
Journal:	Anticancer Res. 2004 Nov-Dec;24(6):3735-42.
Title:	Growth hormone receptor antagonist administration inhibits growth of human colorectal carcinoma in nude mice.
Author:	Dagnaes-Hansen, F\|Duan, H\|Rasmussen, L M\|Friend, K E\|Flyvbjerg, A
PMID:	15736405

95.
Journal:	Int J Cancer. 2005 Feb 10;113(4):588-99.
Title:	Transcriptome analysis of a human colorectal cancer cell line shows molecular targets of insulin-like growth factor-binding protein-4 overexpression.
Author:	Diehl, Daniela\|Lahm, Harald\|Wolf, Eckhard\|Bauersachs, Stefan
PMID:	15455346

96.
Journal:	Int J Colorectal Dis. 2005 May;20(3):287-91. Epub 2004 Oct 15.
Title:	A case of colorectal carcinoma in adenoma analyzed by a cDNA array.
Author:	Nosho, Katsuhiko\|Yamamoto, Hiroyuki\|Takamaru, Hiroyuki\|Hamamoto, Yasuo\|Goto, Akira\|Yoshida, Yukinari\|Arimura, Yoshiaki\|Endo, Takao\|Hirata, Koichi\|Imai, Kohzoh
PMID:	15490195

97.
Journal:	J Gene Med. 2005 Mar;7(3):366-74.
Title:	Regulatory sequences of H19 and IGF2 genes in DNA-based therapy of colorectal rat liver metastases.
Author:	Ohana, Patricia\|Schachter, Pinhas\|Ayesh, Basim\|Mizrahi, Aya\|Birman, Tatiana\|Schneider, Tamar\|Matouk, Imad\|Ayesh, Suhail\|Kuppen, Peter J K\|de Groot, Nathan\|Czerniak, Abraham\|Hochberg, Abraham
PMID:	15521051

98.
Journal:	Int J Colorectal Dis. 2005 May;20(3):203-20.
Title:	The role of the insulin-like growth factor system in colorectal cancer: review of current knowledge.
Author:	Durai, Rajaraman\|Yang, Wenxuan\|Gupta, Sharmila\|Seifalian, Alexander M\|Winslet, Marc C
PMID:	15650828

99.
Journal:	Growth Horm IGF Res. 2005 Feb;15(1):64-71.
Title:	Overexpression of mature insulin-like growth factor (IGF)-II leads to growth arrest in Caco-2 human colon cancer cells.
Author:	Kim, Eun Ji\|Holthuizen, P Elly\|Kim, Jaebong\|Park, Jung Han Yoon
PMID:	15701574

100.
Journal:	Science. 2005 Mar 25;307(5717):1976-8. Epub 2005 Feb 24.
Title:	Loss of imprinting of Igf2 alters intestinal maturation and tumorigenesis in mice.
Author:	Sakatani, Takashi\|Kaneda, Atsushi\|Iacobuzio-Donahue, Christine A\|Carter, Mark G\|de Boom Witzel, Sten\|Okano, Hideyuki\|Ko, Minoru S H\|Ohlsson, Rolf\|Longo, Dan L\|Feinberg, Andrew P
PMID:	15731405

101.
Journal:	Br J Cancer. 2005 Apr 11;92(7):1193-200.
Title:	Gene expression profiling of colorectal adenomas and early invasive carcinomas by cDNA array analysis.
Author:	Nosho, K\|Yamamoto, H\|Adachi, Y\|Endo, T\|Hinoda, Y\|Imai, K
PMID:	15785755

102.
Journal:	Exp Lung Res. 2005 Mar;31(2):145-63.
Title:	Chemoprevention: mouse colon and lung tumor bioassay and modulation of DNA methylation as a biomarker.
Author:	Pereira, Michael A\|Tao, Lian H\|Wang, Wei\|Gunning, William T\|Lubet, Ronald
PMID:	15824018

103.
Journal:	Clin Cancer Res. 2005 May 1;11(9):3494-502.
Title:	Blockade of paracrine supply of insulin-like growth factors using neutralizing antibodies suppresses the liver metastasis of human colorectal cancers.
Author:	Miyamoto, Shin'ichi\|Nakamura, Michio\|Shitara, Kenya\|Nakamura, Kazuyasu\|Ohki, Yuji\|Ishii, Genichiro\|Goya, Masato\|Kodama, Keiji\|Sangai, Takafumi\|Maeda, Hiroyuki\|Shi-Chuang, Zhang\|Chiba, Tsutomu\|Ochiai, Atsushi
PMID:	15867252

104.
Journal:	Sheng Li Ke Xue Jin Zhan. 2005 Jan;36(1):71-3.
Title:	[Loss of IGF2 imprinting in colorectal cancer].
Author:	Wang, Yun\|Li, Guan-Wu\|Wen, Bo-Gui
PMID:	15881352

105.
Journal:	Growth Horm IGF Res. 2005 Jun;15(3):185-92.
Title:	IGFBP-6 five years on; not so 'forgotten'?
Author:	Bach, Leon A
PMID:	15914054

106.
Journal:	Growth Horm IGF Res. 2005 Jun;15(3):215-22. Epub 2005 Apr 20.
Title:	Interleukin-5 potentiates the growth response of Caco-2 cells to IGF-II: a role in colonic carcinogenesis complicating ulcerative colitis?
Author:	Makins, Richard\|Ballinger, Anne
PMID:	15935984

107.
Journal:	Cancer Epidemiol Biomarkers Prev. 2005 Jun;14(6):1402-10.
Title:	Associations between plasma insulin-like growth factor proteins and C-peptide and quality of life in patients with metastatic colorectal cancer.
Author:	Meyerhardt, Jeffrey A\|Sloan, Jeffrey A\|Sargent, Daniel J\|Goldberg, Richard M\|Pollak, Michael\|Morton, Roscoe F\|Ramanathan, Ramesh K\|Williamson, Stephen K\|Findlay, Brian P\|Fuchs, Charles S
PMID:	15941948

108.
Journal:	Cancer Epidemiol Biomarkers Prev. 2005 Jul;14(7):1646-52.
Title:	Leptin, insulin-like growth factor-1, and insulin-like growth factor-2 are mitogens in ApcMin/+ but not Apc+/+ colonic epithelial cell lines.
Author:	Fenton, Jenifer I\|Hord, Norman G\|Lavigne, Jackie A\|Perkins, Susan N\|Hursting, Stephen D
PMID:	16030096

109.
Journal:	Cancer Epidemiol Biomarkers Prev. 2005 Jul;14(7):1819-22.
Title:	Positive correlation of insulin-like growth factor-II with proliferating cell index in patients with colorectal neoplasia.
Author:	Zhao, Ronghua\|Berho, Mariana\|Nogueras, Juan\|Sands, Dana\|Weiss, Eric\|Wexner, Steven\|Giardiello, Francis M\|Cruz-Correa, Marcia
PMID:	16030122

110.
Journal:	Cancer Epidemiol Biomarkers Prev. 2005 Sep;14(9):2076-81.
Title:	Insulin resistance, apoptosis, and colorectal adenoma risk.
Author:	Keku, Temitope O\|Lund, Pauline Kay\|Galanko, Joseph\|Simmons, James G\|Woosley, John T\|Sandler, Robert S
PMID:	16172212

111.
Journal:	Int J Cancer. 2006 Jul 1;119(1):80-3.
Title:	Clinicopathological characteristics of colorectal cancers with loss of imprinting of insulin-like growth factor 2.
Author:	Sasaki, Jun-ichi\|Konishi, Fumio\|Kawamura, Yutaka J\|Kai, Toshihiro\|Takata, Osamu\|Tsukamoto, Toshihiko
PMID:	16432831

112.
Journal:	Cancer Res. 2006 Feb 15;66(4):1940-8.
Title:	Soluble IGF2 receptor rescues Apc(Min/+) intestinal adenoma progression induced by Igf2 loss of imprinting.
Author:	Harper, James\|Burns, Jason L\|Foulstone, Emily J\|Pignatelli, Massimo\|Zaina, Silvio\|Hassan, A Bassim
PMID:	16488992

113.
Journal:	Oncol Rep. 2006 Apr;15(4):791-5.
Title:	Loss of imprinting in IGF2 in colorectal carcinoma assessed by microdissection.
Author:	Maenaka, Shiori\|Hikichi, Tetsurou\|Imai, Miwa A\|Minamoto, Toshinari\|Kawahara, Ei
PMID:	16525660

114.
Journal:	Comb Chem High Throughput Screen. 2006 Mar;9(3):163-70.
Title:	Antagonists of growth hormone-releasing hormone in oncology.
Author:	Schally, Andrew V\|Varga, Jozsef L
PMID:	16533148

115.
Journal:	Mol Cancer Res. 2006 Apr;4(4):283-92.
Title:	Frequent IGF2/H19 domain epigenetic alterations and elevated IGF2 expression in epithelial ovarian cancer.
Author:	Murphy, Susan K\|Huang, Zhiqing\|Wen, Yaqing\|Spillman, Monique A\|Whitaker, Regina S\|Simel, Lauren R\|Nichols, Teresa D\|Marks, Jeffrey R\|Berchuck, Andrew
PMID:	16603642

116.
Journal:	Int J Oncol. 2006 Jun;28(6):1317-25.
Title:	Biology of insulin-like growth factor binding protein-4 and its role in cancer (review).
Author:	Durai, Rajaraman\|Davies, Mark\|Yang, Wenxuan\|Yang, Shi Yu\|Seifalian, Alexander\|Goldspink, Geoffrey\|Winslet, Marc
PMID:	16685432

117.
Journal:	Proteins. 2006 Aug 15;64(3):758-68.
Title:	Computational model for the IGF-II/IGF2r complex that is predictive of mutational and surface plasmon resonance data.
Author:	Roche, Philippe\|Brown, James\|Denley, Adam\|Forbes, Briony E\|Wallace, John C\|Jones, E Yvonne\|Esnouf, Robert M
PMID:	16741994

118.
Journal:	Br J Cancer. 2006 Jul 3;95(1):112-7.
Title:	Insulin-like growth factors and cancer: no role in screening. Evidence from the BUPA study and meta-analysis of prospective epidemiological studies.
Author:	Morris, J K\|George, L M\|Wu, T\|Wald, N J
PMID:	16804529

119.
Journal:	Br J Cancer. 2006 Jul 17;95(2):172-80. Epub 2006 Jul 4.
Title:	Inhibition of insulin receptor isoform-A signalling restores sensitivity to gefitinib in previously de novo resistant colon cancer cells.
Author:	Jones, H E\|Gee, J M W\|Barrow, D\|Tonge, D\|Holloway, B\|Nicholson, R I
PMID:	16819546

120.
Journal:	J Carcinog. 2006 Nov 21;5:24.
Title:	IGF-II transgenic mice display increased aberrant colon crypt multiplicity and tumor volume after 1,2-dimethylhydrazine treatment.
Author:	Diehl, Daniela\|Oesterle, Doris\|Elmlinger, Martin W\|Hoeflich, Andreas\|Wolf, Eckhard\|Lahm, Harald
PMID:	17118177

121.
Journal:	J Cell Biochem. 2007 Jan 1;100(1):58-68.
Title:	Insulin-like growth factors induce apoptosis as well as proliferation in LIM 1215 colon cancer cells.
Author:	Fu, Ping\|Thompson, Julian A\|Leeding, Kerri S\|Bach, Leon A
PMID:	16888814

122.
Journal:	J Nutr. 2007 Feb;137(2):379-83.
Title:	Isolated isoflavones do not affect the circulating insulin-like growth factor system in men at increased colorectal cancer risk.
Author:	Vrieling, Alina\|Rookus, Matti A\|Kampman, Ellen\|Bonfrer, Johannes M G\|Korse, Catharina M\|van Doorn, Jaap\|Lampe, Johanna W\|Cats, Annemieke\|Witteman, Ben J M\|van Leeuwen, Flora E\|van't Veer, Laura J\|Voskuil, Dorien W
PMID:	17237315

123.
Journal:	Hum Pathol. 2007 Apr;38(4):585-92. Epub 2007 Jan 19.
Title:	Cytoplasmic localization of p27 (cyclin-dependent kinase inhibitor 1B/KIP1) in colorectal cancer: inverse correlations with nuclear p27 loss, microsatellite instability, and CpG island methylator phenotype.
Author:	Ogino, Shuji\|Kawasaki, Takako\|Ogawa, Akiyo\|Kirkner, Gregory J\|Loda, Massimo\|Fuchs, Charles S
PMID:	17239930

124.
Journal:	Hum Pathol. 2007 Apr;38(4):614-20. Epub 2007 Jan 31.
Title:	TGFBR2 mutation is correlated with CpG island methylator phenotype in microsatellite instability-high colorectal cancer.
Author:	Ogino, Shuji\|Kawasaki, Takako\|Ogawa, Akiyo\|Kirkner, Gregory J\|Loda, Massimo\|Fuchs, Charles S
PMID:	17270239

125.
Journal:	Clin Cancer Res. 2007 Feb 1;13(3):1000-9.
Title:	Clinical pharmacodynamic effects of the growth hormone receptor antagonist pegvisomant: implications for cancer therapy.
Author:	Yin, Donghua\|Vreeland, Franzanne\|Schaaf, Larry J\|Millham, Robert\|Duncan, Barbara A\|Sharma, Amarnath
PMID:	17289896

126.
Journal:	Dis Markers. 2007;23(1-2):105-12.
Title:	Loss of imprinting of IGF2 as an epigenetic marker for the risk of human cancer.
Author:	Cui, Hengmi
PMID:	17325430

127.
Journal:	Gut. 2007 Nov;56(11):1564-71. Epub 2007 Mar 5.
Title:	Molecular correlates with MGMT promoter methylation and silencing support CpG island methylator phenotype-low (CIMP-low) in colorectal cancer.
Author:	Ogino, Shuji\|Kawasaki, Takako\|Kirkner, Gregory J\|Suemoto, Yuko\|Meyerhardt, Jeffrey A\|Fuchs, Charles S
PMID:	17339237

128.
Journal:	Hum Pathol. 2007 Jun;38(6):842-9. Epub 2007 Mar 12.
Title:	Fatty acid synthase overexpression in colorectal cancer is associated with microsatellite instability, independent of CpG island methylator phenotype.
Author:	Ogino, Shuji\|Kawasaki, Takako\|Ogawa, Akiyo\|Kirkner, Gregory J\|Loda, Massimo\|Fuchs, Charles S
PMID:	17350669

129.
Journal:	Cancer Sci. 2007 May;98(5):685-91.
Title:	Matrix metalloproteinase-7 triggers the matricrine action of insulin-like growth factor-II via proteinase activity on insulin-like growth factor binding protein 2 in the extracellular matrix.
Author:	Miyamoto, Shin'ichi\|Nakamura, Michio\|Yano, Keiichi\|Ishii, Genichiro\|Hasebe, Takahiro\|Endoh, Yasushi\|Sangai, Takafumi\|Maeda, Hiroyuki\|Shi-Chuang, Zhang\|Chiba, Tsutomu\|Ochiai, Atsushi
PMID:	17359288

130.
Journal:	Virchows Arch. 2007 May;450(5):529-37. Epub 2007 Mar 20.
Title:	CpG island methylation, response to combination chemotherapy, and patient survival in advanced microsatellite stable colorectal carcinoma.
Author:	Ogino, Shuji\|Meyerhardt, Jeffrey A\|Kawasaki, Takako\|Clark, Jeffrey W\|Ryan, David P\|Kulke, Matthew H\|Enzinger, Peter C\|Wolpin, Brian M\|Loda, Massimo\|Fuchs, Charles S
PMID:	17372756

131.
Journal:	Eur J Cancer. 2007 May;43(8):1276-82.
Title:	Loss of imprinting of insulin-like growth factor II is associated with increased risk of proximal colon cancer.
Author:	Liou, Jyh-Ming\|Wu, Ming-Shiang\|Lin, Jaw-Town\|Wang, Hsiu-Po\|Huang, Shih-Pei\|Chiu, Han-Mo\|Lee, Yi-Chia\|Lin, Yen-Bo\|Shun, Chia-Tung\|Liang, Jin-Tung
PMID:	17382534

132.
Journal:	Cancer J. 2007 Jan-Feb;13(1):70-4.
Title:	An epigenetic approach to cancer etiology.
Author:	Feinberg, Andrew P
PMID:	17464249

133.
Journal:	BMC Cancer. 2007 May 2;7:72.
Title:	18q loss of heterozygosity in microsatellite stable colorectal cancer is correlated with CpG island methylator phenotype-negative (CIMP-0) and inversely with CIMP-low and CIMP-high.
Author:	Ogino, Shuji\|Kawasaki, Takako\|Kirkner, Gregory J\|Ohnishi, Mutsuko\|Fuchs, Charles S
PMID:	17474983

134.
Journal:	J Biol Chem. 2007 Aug 3;282(31):22298-306.
Title:	Promotion of cancer cell migration: an insulin-like growth factor (IGF)-independent action of IGF-binding protein-6.
Author:	Fu, Ping\|Thompson, Julian A\|Bach, Leon A
PMID:	17519236

135.
Journal:	J Mol Diagn. 2007 Jul;9(3):305-14.
Title:	Evaluation of markers for CpG island methylator phenotype (CIMP) in colorectal cancer by a large population-based sample.
Author:	Ogino, Shuji\|Kawasaki, Takako\|Kirkner, Gregory J\|Kraft, Peter\|Loda, Massimo\|Fuchs, Charles S
PMID:	17591929

136.
Journal:	Carcinogenesis. 2007 Sep;28(9):1985-90. Epub 2007 Jul 9.
Title:	MGMT germline polymorphism is associated with somatic MGMT promoter methylation and gene silencing in colorectal cancer.
Author:	Ogino, Shuji\|Hazra, Aditi\|Tranah, Gregory J\|Kirkner, Gregory J\|Kawasaki, Takako\|Nosho, Katsuhiko\|Ohnishi, Mutsuko\|Suemoto, Yuko\|Meyerhardt, Jeffrey A\|Hunter, David J\|Fuchs, Charles S
PMID:	17621591

137.
Journal:	Ann Surg Oncol. 2007 Oct;14(10):2838-46. Epub 2007 Jul 26.
Title:	Targeting of insulin-like growth factor-I receptor with a monoclonal antibody inhibits growth of hepatic metastases from human colon carcinoma in mice.
Author:	Bauer, Todd W\|Fan, Fan\|Liu, Wenbiao\|Camp, Ernest R\|Yang, Anthony\|Somcio, Ray J\|Bucana, Corazon D\|Singh, Rajeeva\|Ellis, Lee M
PMID:	17653802

138.
Journal:	Mol Cancer Ther. 2007 Aug;6(8):2158-67. Epub 2007 Aug 1.
Title:	A novel, potent, and selective insulin-like growth factor-I receptor kinase inhibitor blocks insulin-like growth factor-I receptor signaling in vitro and inhibits insulin-like growth factor-I receptor dependent tumor growth in vivo.
Author:	Ji, Qun-sheng\|Mulvihill, Mark J\|Rosenfeld-Franklin, Maryland\|Cooke, Andrew\|Feng, Lixin\|Mak, Gilda\|O'Connor, Matthew\|Yao, Yan\|Pirritt, Caroline\|Buck, Elizabeth\|Eyzaguirre, Alexandra\|Arnold, Lee D\|Gibson, Neil W\|Pachter, Jonathan A
PMID:	17671083

139.
Journal:	Neoplasia. 2007 Jul;9(7):569-77.
Title:	Correlation of beta-catenin localization with cyclooxygenase-2 expression and CpG island methylator phenotype (CIMP) in colorectal cancer.
Author:	Kawasaki, Takako\|Nosho, Katsuhiko\|Ohnishi, Mutsuko\|Suemoto, Yuko\|Kirkner, Gregory J\|Dehari, Reiko\|Meyerhardt, Jeffrey A\|Fuchs, Charles S\|Ogino, Shuji
PMID:	17710160

140.
Journal:	Invest Ophthalmol Vis Sci. 2007 Oct;48(10):4403-6.
Title:	Promoter methylation status of multiple genes in uveal melanoma.
Author:	Merhavi, Efrat\|Cohen, Yoram\|Avraham, Bat Chen R\|Frenkel, Shahar\|Chowers, Itay\|Pe'er, Jacob\|Goldenberg-Cohen, Nitza
PMID:	17898258

141.
Journal:	Am J Clin Nutr. 2007 Nov;86(5):1456-62.
Title:	Lycopene supplementation elevates circulating insulin-like growth factor binding protein-1 and -2 concentrations in persons at greater risk of colorectal cancer.
Author:	Vrieling, Alina\|Voskuil, Dorien W\|Bonfrer, Johannes M\|Korse, Catharina M\|van Doorn, Jaap\|Cats, Annemieke\|Depla, Annekatrien C\|Timmer, Robin\|Witteman, Ben J\|van Leeuwen, Flora E\|Van't Veer, Laura J\|Rookus, Matti A\|Kampman, Ellen
PMID:	17991659

142.
Journal:	Genes Dev. 2007 Dec 1;21(23):3110-22.
Title:	Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing.
Author:	Linhart, Heinz G\|Lin, Haijiang\|Yamada, Yasuhiro\|Moran, Eva\|Steine, Eveline J\|Gokhale, Sumita\|Lo, Grace\|Cantu, Erika\|Ehrich, Mathias\|He, Timothy\|Meissner, Alex\|Jaenisch, Rudolf
PMID:	18056424

143.
Journal:	Neoplasia. 2007 Dec;9(12):1091-8.
Title:	IGFBP3 promoter methylation in colorectal cancer: relationship with microsatellite instability, CpG island methylator phenotype, and p53.
Author:	Kawasaki, Takako\|Nosho, Katsuhiko\|Ohnishi, Mutsuko\|Suemoto, Yuko\|Kirkner, Gregory J\|Fuchs, Charles S\|Ogino, Shuji
PMID:	18084616

144.
Journal:	Proc Natl Acad Sci U S A. 2007 Dec 26;104(52):20926-31.
Title:	Enhanced sensitivity to IGF-II signaling links loss of imprinting of IGF2 to increased cell proliferation and tumor risk.
Author:	Kaneda, Atsushi\|Wang, Chiaochun J\|Cheong, Raymond\|Timp, Winston\|Onyango, Patrick\|Wen, Bo\|Iacobuzio-Donahue, Christine A\|Ohlsson, Rolf\|Andraos, Rita\|Pearson, Mark A\|Sharov, Alexei A\|Longo, Dan L\|Ko, Minoru S H\|Levchenko, Andre\|Feinberg, Andrew P
PMID:	18087038

145.
Journal:	Growth Horm IGF Res. 2008 Jun;18(3):198-204.
Title:	Assessing the potential usefulness of IGF-related peptides and adiponectin for predicting disease risk.
Author:	Belobrajdic, Damien P\|Priebe, Ilka K\|Forbes, Briony\|Flyvbjerg, Allan\|Chen, Jian-Wen\|Cosgrove, Leah J\|Frystyk, Jan\|Saunders, Ian W
PMID:	17928251

146.
Journal:	Fertil Steril. 2008 Oct;90(4):1236-9.
Title:	Increased insulin-like growth factor-1 after oophorectomy in postmenopausal women.
Author:	Fogle, Robin H\|Chang, Lilly\|Patel, Sherfaraz K\|Stanczyk, Frank Z\|Paulson, Richard J
PMID:	18054929

147.
Journal:	Mod Pathol. 2008 Feb;21(2):150-8. Epub 2007 Dec 14.
Title:	WRN promoter methylation possibly connects mucinous differentiation, microsatellite instability and CpG island methylator phenotype in colorectal cancer.
Author:	Kawasaki, Takako\|Ohnishi, Mutsuko\|Suemoto, Yuko\|Kirkner, Gregory J\|Liu, Zhiqian\|Yamamoto, Hiroyuki\|Loda, Massimo\|Fuchs, Charles S\|Ogino, Shuji
PMID:	18084250

148.
Journal:	Nat Clin Pract Endocrinol Metab. 2008 Jan;4(1):33-43.
Title:	Antagonists of growth-hormone-releasing hormone: an emerging new therapy for cancer.
Author:	Schally, Andrew V\|Varga, Jozsef L\|Engel, Jorg B
PMID:	18084344

149.
Journal:	Mod Pathol. 2008 Mar;21(3):245-55.
Title:	CpG island methylator phenotype-low (CIMP-low) colorectal cancer shows not only few methylated CIMP-high-specific CpG islands, but also low-level methylation at individual loci.
Author:	Kawasaki, Takako\|Ohnishi, Mutsuko\|Nosho, Katsuhiko\|Suemoto, Yuko\|Kirkner, Gregory J\|Meyerhardt, Jeffrey A\|Fuchs, Charles S\|Ogino, Shuji
PMID:	18204436

150.
Journal:	Oncogene. 2008 Jul 3;27(29):4024-33.
Title:	Autocrine induction of invasion and metastasis by tumor-associated trypsin inhibitor in human colon cancer cells.
Author:	Gouyer, V\|Fontaine, D\|Dumont, P\|de Wever, O\|Fontayne-Devaud, H\|Leteurtre, E\|Truant, S\|Delacour, D\|Drobecq, H\|Kerckaert, J-P\|de Launoit, Y\|Bracke, M\|Gespach, C\|Desseyn, J-L\|Huet, G
PMID:	18317448

151.
Journal:	PLoS One. 2008 Mar 26;3(3):e1849.
Title:	Distinct methylation changes at the IGF2-H19 locus in congenital growth disorders and cancer.
Author:	Murrell, Adele\|Ito, Yoko\|Verde, Gaetano\|Huddleston, Joanna\|Woodfine, Kathryn\|Silengo, Margherita Cirillo\|Spreafico, Filippo\|Perotti, Daniela\|De Crescenzo, Agostina\|Sparago, Angela\|Cerrato, Flavia\|Riccio, Andrea
PMID:	18365005

152.
Journal:	Int J Cancer. 2008 Jun 15;122(12):2767-73.
Title:	LINE-1 hypomethylation is inversely associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer.
Author:	Ogino, Shuji\|Kawasaki, Takako\|Nosho, Katsuhiko\|Ohnishi, Mutsuko\|Suemoto, Yuko\|Kirkner, Gregory J\|Fuchs, Charles S
PMID:	18366060

153.
Journal:	Neoplasia. 2008 Jun;10(6):534-41.
Title:	PIK3CA mutation in colorectal cancer: relationship with genetic and epigenetic alterations.
Author:	Nosho, Katsuhiko\|Kawasaki, Takako\|Ohnishi, Mutsuko\|Suemoto, Yuko\|Kirkner, Gregory J\|Zepf, Dimity\|Yan, Liying\|Longtine, Janina A\|Fuchs, Charles S\|Ogino, Shuji
PMID:	18516290

154.
Journal:	Hum Mol Genet. 2008 Sep 1;17(17):2633-43.
Title:	Somatically acquired hypomethylation of IGF2 in breast and colorectal cancer.
Author:	Ito, Yoko\|Koessler, Thibaud\|Ibrahim, Ashraf E K\|Rai, Sushma\|Vowler, Sarah L\|Abu-Amero, Sayeda\|Silva, Ana-Luisa\|Maia, Ana-Teresa\|Huddleston, Joanna E\|Uribe-Lewis, Santiago\|Woodfine, Kathryn\|Jagodic, Maja\|Nativio, Raffaella\|Dunning, Alison\|Moore, Gudrun\|Kle
PMID:	18541649

155.
Journal:	Hum Pathol. 2008 Sep;39(9):1301-8.
Title:	Genetic alterations in colorectal cancers with demethylation of insulin-like growth factor II.
Author:	Ohta, Miki\|Sugimoto, Takafumi\|Seto, Motoko\|Mohri, Dai\|Asaoka, Yoshinari\|Tada, Motohisa\|Tanaka, Yasuo\|Yamaji, Yutaka\|Kanai, Fumihiko\|Kawabe, Takao\|Omata, Masao
PMID:	18619647

156.
Journal:	Hum Pathol. 2008 Oct;39(10):1483-94.
Title:	Up-regulation of the hypoxia-inducible factor-1 transcriptional pathway in colorectal carcinomas.
Author:	Furlan, Daniela\|Sahnane, Nora\|Carnevali, Ileana\|Cerutti, Roberta\|Bertoni, Francesco\|Kwee, Ivo\|Uccella, Silvia\|Bertolini, Valentina\|Chiaravalli, Anna Maria\|Capella, Carlo
PMID:	18619649

157.
Journal:	Cancer Epidemiol Biomarkers Prev. 2008 Jul;17(7):1774-80.
Title:	Ethnicity and risk for colorectal cancers showing somatic BRAF V600E mutation or CpG island methylator phenotype.
Author:	English, Dallas R\|Young, Joanne P\|Simpson, Julie A\|Jenkins, Mark A\|Southey, Melissa C\|Walsh, Michael D\|Buchanan, Daniel D\|Barker, Melissa A\|Haydon, Andrew M\|Royce, Simon G\|Roberts, Aedan\|Parry, Susan\|Hopper, John L\|Jass, Jeremy J\|Giles, Graham G
PMID:	18628431

158.
Journal:	Oncol Rep. 2008 Aug;20(2):359-64.
Title:	Clinicopathological significance of the gene expression of matrix metalloproteinase-7, insulin-like growth factor-1, insulin-like growth factor-2 and insulin-like growth factor-1 receptor in patients with colorectal cancer: insulin-like growth factor-1 re
Author:	Oshima, Takashi\|Akaike, Makoto\|Yoshihara, Kazue\|Shiozawa, Manabu\|Yamamoto, Naoto\|Sato, Tsutomu\|Yamada, Roppei\|Fujii, Shoich\|Rino, Yasushi\|Kunisaki, Chikara\|Tanaka, Katsuaki\|Masuda, Munetaka\|Imada, Toshio
PMID:	18636198

159.
Journal:	Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12417-22.
Title:	The H19 locus acts in vivo as a tumor suppressor.
Author:	Yoshimizu, Tomomi\|Miroglio, Audrey\|Ripoche, Marie-Anne\|Gabory, Anne\|Vernucci, Maria\|Riccio, Andrea\|Colnot, Sabine\|Godard, Cecile\|Terris, Benoit\|Jammes, Helene\|Dandolo, Luisa
PMID:	18719115

160.
Journal:	Arch Pathol Lab Med. 2008 Oct;132(10):1657-65.
Title:	CpG island methylator phenotype in colorectal cancers: comparison of the new and classic CpG island methylator phenotype marker panels.
Author:	Lee, Sun\|Cho, Nam-Yun\|Yoo, Eun Joo\|Kim, Jung Ho\|Kang, Gyeong Hoon
PMID:	18834226

161.
Journal:	Cancer Epidemiol Biomarkers Prev. 2008 Oct;17(10):2585-93.
Title:	No effect of red clover-derived isoflavone intervention on the insulin-like growth factor system in women at increased risk of colorectal cancer.
Author:	Vrieling, Alina\|Rookus, Matti A\|Kampman, Ellen\|Bonfrer, Johannes M G\|Bosma, Astrid\|Cats, Annemieke\|van Doorn, Jaap\|Korse, Catharina M\|Witteman, Ben J M\|van Leeuwen, Flora E\|van't Veer, Laura J\|Voskuil, Dorien W
PMID:	18842999

162.
Journal:	J Biol Chem. 2008 Dec 12;283(50):35295-304.
Title:	Unbiased screening for transcriptional targets of ZKSCAN3 identifies integrin beta 4 and vascular endothelial growth factor as downstream targets.
Author:	Yang, Lin\|Zhang, Li\|Wu, Qiuyu\|Boyd, Douglas D
PMID:	18940803

163.
Journal:	Histopathology. 2008 Nov;53(5):588-98.
Title:	Cyclin D1 is frequently overexpressed in microsatellite unstable colorectal cancer, independent of CpG island methylator phenotype.
Author:	Nosho, K\|Kawasaki, T\|Chan, A T\|Ohnishi, M\|Suemoto, Y\|Kirkner, G J\|Fuchs, C S\|Ogino, S
PMID:	18983468

164.
Journal:	PLoS One. 2008;3(11):e3698.
Title:	Comprehensive biostatistical analysis of CpG island methylator phenotype in colorectal cancer using a large population-based sample.
Author:	Nosho, Katsuhiko\|Irahara, Natsumi\|Shima, Kaori\|Kure, Shoko\|Kirkner, Gregory J\|Schernhammer, Eva S\|Hazra, Aditi\|Hunter, David J\|Quackenbush, John\|Spiegelman, Donna\|Giovannucci, Edward L\|Fuchs, Charles S\|Ogino, Shuji
PMID:	19002263

165.
Journal:	Clin Cancer Res. 2008 Dec 15;14(24):8263-9.
Title:	Plasma insulin-like growth factors, insulin-like binding protein-3, and outcome in metastatic colorectal cancer: results from intergroup trial N9741.
Author:	Fuchs, Charles S\|Goldberg, Richard M\|Sargent, Daniel J\|Meyerhardt, Jeffrey A\|Wolpin, Brian M\|Green, Erin M\|Pitot, Henry C\|Pollak, Michael
PMID:	19073970

166.
Journal:	Growth Horm IGF Res. 2009 Apr;19(2):126-35.
Title:	Expression of insulin-like growth factor system components in colorectal tissue and its relation with serum IGF levels.
Author:	Vrieling, Alina\|Voskuil, Dorien W\|Bosma, Astrid\|Majoor, Donne M\|van Doorn, Jaap\|Cats, Annemieke\|Depla, Annekatrien C T M\|Timmer, Robin\|Witteman, Ben J M\|Wesseling, Jelle\|Kampman, Ellen\|Van't Veer, Laura J
PMID:	18801683

167.
Journal:	Gut. 2009 Jan;58(1):90-6.
Title:	CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer.
Author:	Ogino, Shuji\|Nosho, Katsuhiko\|Kirkner, Gregory J\|Kawasaki, Takako\|Meyerhardt, Jeffrey A\|Loda, Massimo\|Giovannucci, Edward L\|Fuchs, Charles S
PMID:	18832519

168.
Journal:	Neoplasia. 2009 Jan;11(1):87-95.
Title:	JC virus T-antigen in colorectal cancer is associated with p53 expression and chromosomal instability, independent of CpG island methylator phenotype.
Author:	Nosho, Katsuhiko\|Shima, Kaori\|Kure, Shoko\|Irahara, Natsumi\|Baba, Yoshifumi\|Chen, Li\|Kirkner, Gregory J\|Fuchs, Charles S\|Ogino, Shuji
PMID:	19107235

169.
Journal:	Nutr Cancer. 2009;61(1):146-55.
Title:	Dietary carbohydrate source alters gene expression profile of intestinal epithelium in mice.
Author:	Wang, Bing\|Bobe, Gerd\|LaPres, John J\|Bourquin, Leslie D
PMID:	19116885

170.
Journal:	Epigenetics. 2009 Feb 16;4(2):114-8. Epub 2009 Feb 27.
Title:	Temporal stability and age-related prevalence of loss of imprinting of the insulin-like growth factor-2 gene.
Author:	Cruz-Correa, Marcia\|Zhao, Ronghua\|Oviedo, Myriam\|Bernabe, Raul D\|Lacourt, Mercedes\|Cardona, Alberto\|Lopez-Enriquez, Reynold\|Wexner, Steven\|Cuffari, Carmen\|Hylind, Linda\|Platz, Elizabeth\|Cui, Hengmi\|Feinberg, Andrew P\|Giardiello, Francis M
PMID:	19242102

171.
Journal:	Clin Cancer Res. 2009 May 1;15(9):3068-75.
Title:	Supplementation with branched-chain amino acids inhibits azoxymethane-induced colonic preneoplastic lesions in male C57BL/KsJ-db/db mice.
Author:	Shimizu, Masahito\|Shirakami, Yohei\|Iwasa, Junpei\|Shiraki, Makoto\|Yasuda, Yoichi\|Hata, Kazuya\|Hirose, Yoshinobu\|Tsurumi, Hisashi\|Tanaka, Takuji\|Moriwaki, Hisataka
PMID:	19366832

172.
Journal:	Mod Pathol. 2009 Jul;22(7):922-32.
Title:	SIRT1 histone deacetylase expression is associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer.
Author:	Nosho, Katsuhiko\|Shima, Kaori\|Irahara, Natsumi\|Kure, Shoko\|Firestein, Ron\|Baba, Yoshifumi\|Toyoda, Saori\|Chen, Li\|Hazra, Aditi\|Giovannucci, Edward L\|Fuchs, Charles S\|Ogino, Shuji
PMID:	19430421

173.
Journal:	Clin Cancer Res. 2009 Jun 1;15(11):3663-71.
Title:	DNMT3B expression might contribute to CpG island methylator phenotype in colorectal cancer.
Author:	Nosho, Katsuhiko\|Shima, Kaori\|Irahara, Natsumi\|Kure, Shoko\|Baba, Yoshifumi\|Kirkner, Gregory J\|Chen, Li\|Gokhale, Sumita\|Hazra, Aditi\|Spiegelman, Donna\|Giovannucci, Edward L\|Jaenisch, Rudolf\|Fuchs, Charles S\|Ogino, Shuji
PMID:	19470733

174.
Journal:	Adv Med Sci. 2009;54(1):51-8.
Title:	IGF-I, IGF-II, IGFBP2, IGFBP3 and acid-labile subunit (ALS) in colorectal cancer patients before surgery and during one year follow up in relation to age.
Author:	Sztefko, K\|Hodorowicz-Zaniewska, D\|Popiela, T\|Richter, P
PMID:	19482725

175.
Journal:	Cancer Res. 2009 Jul 1;69(13):5400-5.
Title:	Insulin-like growth factor-II methylation status in lymphocyte DNA and colon cancer risk in the Northern Sweden Health and Disease cohort.
Author:	Kaaks, Rudolf\|Stattin, Par\|Villar, Stephanie\|Poetsch, Anna R\|Dossus, Laure\|Nieters, Alexandra\|Riboli, Elio\|Palmqvist, Richard\|Hallmans, Goran\|Plass, Christoph\|Friesen, Marlin D
PMID:	19549920

176.
Journal:	Mol Cancer Ther. 2009 Aug;8(8):2110-21.
Title:	Molecular predictors of response to a humanized anti-insulin-like growth factor-I receptor monoclonal antibody in breast and colorectal cancer.
Author:	Zha, Jiping\|O'Brien, Carol\|Savage, Heidi\|Huw, Ling-Yuh\|Zhong, Fiona\|Berry, Leanne\|Lewis Phillips, Gail D\|Luis, Elizabeth\|Cavet, Guy\|Hu, Xiaolan\|Amler, Lukas C\|Lackner, Mark R
PMID:	19671761

177.
Journal:	Gastroenterology. 2009 Nov;137(5):1609-20.e1-3.
Title:	A prospective cohort study shows unique epigenetic, genetic, and prognostic features of synchronous colorectal cancers.
Author:	Nosho, Katsuhiko\|Kure, Shoko\|Irahara, Natsumi\|Shima, Kaori\|Baba, Yoshifumi\|Spiegelman, Donna\|Meyerhardt, Jeffrey A\|Giovannucci, Edward L\|Fuchs, Charles S\|Ogino, Shuji
PMID:	19686742

178.
Journal:	Cancer Epidemiol Biomarkers Prev. 2009 Oct;18(10):2765-72.
Title:	Vitamin D receptor expression is associated with PIK3CA and KRAS mutations in colorectal cancer.
Author:	Kure, Shoko\|Nosho, Katsuhiko\|Baba, Yoshifumi\|Irahara, Natsumi\|Shima, Kaori\|Ng, Kimmie\|Meyerhardt, Jeffrey A\|Giovannucci, Edward L\|Fuchs, Charles S\|Ogino, Shuji
PMID:	19789368

179.
Journal:	Clin Cancer Res. 2009 Oct 15;15(20):6412-20.
Title:	Lymphocytic reaction to colorectal cancer is associated with longer survival, independent of lymph node count, microsatellite instability, and CpG island methylator phenotype.
Author:	Ogino, Shuji\|Nosho, Katsuhiko\|Irahara, Natsumi\|Meyerhardt, Jeffrey A\|Baba, Yoshifumi\|Shima, Kaori\|Glickman, Jonathan N\|Ferrone, Cristina R\|Mino-Kenudson, Mari\|Tanaka, Noriko\|Dranoff, Glenn\|Giovannucci, Edward L\|Fuchs, Charles S
PMID:	19825961

180.
Journal:	Asian Pac J Cancer Prev. 2009 Dec;10 Suppl:29-35.
Title:	Association of serum retinol and carotenoids with insulin-like growth factors and insulin-like growth factor binding protein-3 among control subjects of a nested case-control study in the Japan Collaborative Cohort Study.
Author:	Suzuki, Koji\|Ito, Yoshinori\|Hashimoto, Shuji\|Kawado, Miyuki\|Inoue, Takashi\|Ando, Masahiko\|Watanabe, Yoshiyuki\|Inaba, Yutaka\|Tajima, Kazuo\|Nakachi, Kei\|Tamakoshi, Akiko
PMID:	20553078

181.
Journal:	Asian Pac J Cancer Prev. 2009 Dec;10 Suppl:45-9.
Title:	Insulin-like growth factor (IGF)-I, IGF-II, IGF binding protein-3, and risk of colorectal cancer: a nested case-control study in the Japan Collaborative Cohort study.
Author:	Suzuki, Sadao\|Kojima, Masayo\|Tokudome, Shinkan\|Suzuki, Koji\|Ozasa, Kotaro\|Ito, Yoshinori\|Inaba, Yutaka\|Tajima, Kazuo\|Nakachi, Kei\|Watanabe, Yoshiyuki\|Tamakoshi, Akiko
PMID:	20553081

182.
Journal:	Int J Cancer. 2010 Aug 1;127(3):568-77.
Title:	Loss of imprinting and marked gene elevation are 2 forms of aberrant IGF2 expression in colorectal cancer.
Author:	Cheng, Yu-Wei\|Idrees, Kamran\|Shattock, Richard\|Khan, Sajid A\|Zeng, Zhaoshi\|Brennan, Cameron W\|Paty, Philip\|Barany, Francis
PMID:	19957330

183.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2010 Apr;298(4):G551-62.
Title:	Insulin-like growth factors are more effective than progastrin in reversing proapoptotic effects of curcumin: critical role of p38MAPK.
Author:	Singh, Pomila\|Sarkar, Shubhashish\|Umar, Shahid\|Rengifo-Cam, William\|Singh, Amar P\|Wood, Thomas G
PMID:	20133951

184.
Journal:	J Clin Endocrinol Metab. 2010 Apr;95(4):1717-25.
Title:	Plasma insulin-like growth factor-binding protein-2 levels as diagnostic and prognostic biomarker of colorectal cancer.
Author:	Liou, Jyh-Ming\|Shun, Chia-Tung\|Liang, Jin-Tung\|Chiu, Han-Mo\|Chen, Mei-Jyh\|Chen, Chien-Chuan\|Wang, Hsiu-Po\|Wu, Ming-Shiang\|Lin, Jaw-Town
PMID:	20157191

185.
Journal:	Endocrinology. 2010 Apr;151(4):1418-27.
Title:	Silencing of the insulin receptor isoform A favors formation of type 1 insulin-like growth factor receptor (IGF-IR) homodimers and enhances ligand-induced IGF-IR activation and viability of human colon carcinoma cells.
Author:	Brierley, G V\|Macaulay, S L\|Forbes, B E\|Wallace, J C\|Cosgrove, L J\|Macaulay, V M
PMID:	20179263

186.
Journal:	Cancer Epidemiol Biomarkers Prev. 2010 Mar;19(3):822-31.
Title:	PTGER2 overexpression in colorectal cancer is associated with microsatellite instability, independent of CpG island methylator phenotype.
Author:	Baba, Yoshifumi\|Nosho, Katsuhiko\|Shima, Kaori\|Goessling, Wolfram\|Chan, Andrew T\|Ng, Kimmie\|Chan, Jennifer A\|Giovannucci, Edward L\|Fuchs, Charles S\|Ogino, Shuji
PMID:	20200425

187.
Journal:	Chem Biol Interact. 2010 May 14;185(3):247-52.
Title:	(-)-Epigallocatechin gallate inhibits growth and activation of the VEGF/VEGFR axis in human colorectal cancer cells.
Author:	Shimizu, Masahito\|Shirakami, Yohei\|Sakai, Hiroyasu\|Yasuda, Yoichi\|Kubota, Masaya\|Adachi, Seiji\|Tsurumi, Hisashi\|Hara, Yukihiko\|Moriwaki, Hisataka
PMID:	20346928

188.
Journal:	Cancer Epidemiol. 2010 Jun;34(3):338-44.
Title:	Polymorphisms in methyl-group metabolism genes and risk of sporadic colorectal cancer with relation to the CpG island methylator phenotype.
Author:	Karpinski, Pawel\|Myszka, Aleksander\|Ramsey, David\|Misiak, Blazej\|Gil, Justyna\|Laczmanska, Izabela\|Grzebieniak, Zygmunt\|Sebzda, Tadeusz\|Smigiel, Robert\|Stembalska, Agnieszka\|Sasiadek, Maria M
PMID:	20381446

189.
Journal:	Gut. 2010 Sep;59(9):1236-44.
Title:	Expression of an ASCL2 related stem cell signature and IGF2 in colorectal cancer liver metastases with 11p15.5 gain.
Author:	Stange, D E\|Engel, F\|Longerich, T\|Koo, B K\|Koch, M\|Delhomme, N\|Aigner, M\|Toedt, G\|Schirmacher, P\|Lichter, P\|Weitz, J\|Radlwimmer, B
PMID:	20479215

190.
Journal:	Gastroenterology. 2010 Dec;139(6):1855-64.
Title:	Hypomethylation of the IGF2 DMR in colorectal tumors, detected by bisulfite pyrosequencing, is associated with poor prognosis.
Author:	Baba, Yoshifumi\|Nosho, Katsuhiko\|Shima, Kaori\|Huttenhower, Curtis\|Tanaka, Noriko\|Hazra, Aditi\|Giovannucci, Edward L\|Fuchs, Charles S\|Ogino, Shuji
PMID:	20682317

191.
Journal:	Clin Colorectal Cancer. 2010 Oct;9(4):219-23.
Title:	The insulin-like growth factor signaling pathway as a target for treatment of colorectal carcinoma.
Author:	Ewing, Gideon P\|Goff, Laura W
PMID:	20920993

192.
Journal:	Am J Pathol. 2010 Dec;177(6):2731-40.
Title:	Novel application of structural equation modeling to correlation structure analysis of CpG island methylation in colorectal cancer.
Author:	Tanaka, Noriko\|Huttenhower, Curtis\|Nosho, Katsuhiko\|Baba, Yoshifumi\|Shima, Kaori\|Quackenbush, John\|Haigis, Kevin M\|Giovannucci, Edward\|Fuchs, Charles S\|Ogino, Shuji
PMID:	21037082

193.
Journal:	PLoS One. 2010 Oct 21;5(10):e13556.
Title:	Evaluation of allelic expression of imprinted genes in adult human blood.
Author:	Frost, Jennifer M\|Monk, Dave\|Stojilkovic-Mikic, Taita\|Woodfine, Kathryn\|Chitty, Lyn S\|Murrell, Adele\|Stanier, Philip\|Moore, Gudrun E
PMID:	21042416

194.
Journal:	Epigenomics. 2010 Jun;2(3):365-75.
Title:	Specific hypomethylated CpGs at the IGF2 locus act as an epigenetic biomarker for familial adenomatous polyposis colorectal cancer.
Author:	Miroglio, Audrey\|Jammes, Helene\|Tost, Jorg\|Ponger, Loic\|Gut, Ivo Glynne\|El Abdalaoui, Hafida\|Coste, Joel\|Chaussade, Stanislas\|Arimondo, Paola B\|Lamarque, Dominique\|Dandolo, Luisa
PMID:	22121898

195.
Journal:	Int J Cancer. 2011 Mar 1;128(5):1080-94.
Title:	Prognostic significance of CDKN2A (p16) promoter methylation and loss of expression in 902 colorectal cancers: Cohort study and literature review.
Author:	Shima, Kaori\|Nosho, Katsuhiko\|Baba, Yoshifumi\|Cantor, Mami\|Meyerhardt, Jeffrey A\|Giovannucci, Edward L\|Fuchs, Charles S\|Ogino, Shuji
PMID:	20473920

196.
Journal:	Int J Cancer. 2011 Apr 15;128(8):1843-51.
Title:	The development of composite circulating biomarker models for use in anticancer drug clinical development.
Author:	Lancashire, Lee J\|Roberts, Darren L\|Dive, Caroline\|Renehan, Andrew G
PMID:	20549702

197.
Journal:	Gut. 2011 Apr;60(4):499-508.
Title:	Sequential DNA methylation changes are associated with DNMT3B overexpression in colorectal neoplastic progression.
Author:	Ibrahim, Ashraf E K\|Arends, Mark J\|Silva, Ana-Luisa\|Wyllie, Andrew H\|Greger, Liliana\|Ito, Yoko\|Vowler, Sarah L\|Huang, Tim H-M\|Tavare, Simon\|Murrell, Adele\|Brenton, James D
PMID:	21068132

198.
Journal:	Cancer Causes Control. 2011 Feb;22(2):301-9.
Title:	MGMT promoter methylation, loss of expression and prognosis in 855 colorectal cancers.
Author:	Shima, Kaori\|Morikawa, Teppei\|Baba, Yoshifumi\|Nosho, Katsuhiko\|Suzuki, Maiko\|Yamauchi, Mai\|Hayashi, Marika\|Giovannucci, Edward\|Fuchs, Charles S\|Ogino, Shuji
PMID:	21140203

199.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2011 Jul;301(1):G1-8.
Title:	The "cryptic" mechanism of action of glucagon-like peptide-2.
Author:	Rowland, Katherine J\|Brubaker, Patricia L
PMID:	21527727

200.
Journal:	Tumour Biol. 2011 Aug;32(4):653-9.
Title:	Detection of viral DNA sequences in sporadic colorectal cancers in relation to CpG island methylation and methylator phenotype.
Author:	Karpinski, Pawel\|Myszka, Aleksander\|Ramsey, David\|Kielan, Wojciech\|Sasiadek, Maria Malgorzata
PMID:	21625944

201.
Journal:	PLoS One. 2011;6(6):e21102.
Title:	B vitamins, methionine and alcohol intake and risk of colon cancer in relation to BRAF mutation and CpG island methylator phenotype (CIMP).
Author:	Schernhammer, Eva S\|Giovannucci, Edward\|Baba, Yoshifumi\|Fuchs, Charles S\|Ogino, Shuji
PMID:	21738611

202.
Journal:	Int J Immunopathol Pharmacol. 2011 Jul-Sep;24(3):781-7.
Title:	Analysis of expression profile of gene encoding proteins of signal cascades activated by insulin-like growth factors in colorectal cancer.
Author:	Nowakowska-Zajdel, E\|Mazurek, U\|Ziolko, E\|Niedworok, E\|Fatyga, E\|Kokot, T\|Muc-Wierzgon, Malgorzata
PMID:	21978709

203.
Journal:	Cancer Res Treat. 2011 Sep;43(3):189-94.
Title:	No Association of Insulin-like Growth Factor Gene Polymorphisms with Survival in Patients with Colorectal Cancer.
Author:	Cho, Yoon Young\|Kim, Jong Gwang\|Chae, Yee Soo\|Sohn, Sang Kyun\|Kang, Byung Woog\|Moon, Joon Ho\|Jeon, Seong Woo\|Park, Jun Seok\|Park, Jin Young\|Choi, Gyu Seog
PMID:	22022297

204.
Journal:	Int J Mol Sci. 2011;12(11):8133-45.
Title:	C57BL/KsJ-db/db-Apc mice exhibit an increased incidence of intestinal neoplasms.
Author:	Hata, Kazuya\|Kubota, Masaya\|Shimizu, Masahito\|Moriwaki, Hisataka\|Kuno, Toshiya\|Tanaka, Takuji\|Hara, Akira\|Hirose, Yoshinobu
PMID:	22174655

205.
Journal:	Front Genet. 2011 May 23;2:23.
Title:	Effect of maternal and post-weaning folate supply on gene-specific DNA methylation in the small intestine of weaning and adult apc and wild type mice.
Author:	McKay, Jill A\|Williams, Elizabeth A\|Mathers, John C
PMID:	22303319

206.
Journal:	Oncol Lett. 2011 Nov;2(6):1155-1159.
Title:	IGF-IR in patients with advanced colorectal cancer in correlation with certain clinico-morphological factors: Initial report.
Author:	Kuklinski, Adam\|Kamocki, Zbigniew\|Koda, Mariusz\|Piotrowski, Zdzislaw\|Sulkowski, Stanislaw\|Lesniewicz, Ryszard\|Pawlak, Krystyna\|Mysliwiec, Piotr\|Kedra, Boguslaw
PMID:	22848281

207.
Journal:	Int J Surg Pathol. 2012 Apr;20(2):185-90.
Title:	Rhabdoid carcinoma of the colon: a distinct entity with a very aggressive behavior: a case report associated with a polyposis coli and review of the literature.
Author:	Remo, Andrea\|Zanella, Caterina\|Molinari, Enrico\|Talamini, Alberto\|Tollini, Filippo\|Piacentini, Paolo\|Battaglia, Paolo\|Baritono, Elisabetta\|Bonetti, Andrea\|Lanza, Franco\|Fasolin, Antonio\|Manfrin, Erminia\|Vendraminelli, Roberto
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208.
Journal:	Int J Cancer. 2012 Jul 15;131(2):E105-13.
Title:	Serum IGF1, IGF2 and IGFBP3 and risk of advanced colorectal adenoma.
Author:	Gao, Ying\|Katki, Hormuzd\|Graubard, Barry\|Pollak, Michael\|Martin, Michael\|Tao, Yuzhen\|Schoen, Robert E\|Church, Timothy\|Hayes, Richard B\|Greene, Mark H\|Berndt, Sonja I
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209.
Journal:	Surgery. 2012 Apr;151(4):564-70.
Title:	CpG island methylator phenotype infers a poor disease-free survival in locally advanced rectal cancer.
Author:	Jo, Peter\|Jung, Klaus\|Grade, Marian\|Conradi, Lena-Christin\|Wolff, Hendrik A\|Kitz, Julia\|Becker, Heinz\|Ruschoff, Josef\|Hartmann, Arndt\|Beissbarth, Tim\|Muller-Dornieden, Annegret\|Ghadimi, Michael\|Schneider-Stock, Regine\|Gaedcke, Jochen
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210.
Journal:	Int J Oncol. 2012 Apr;40(4):1251-8.
Title:	Multiple antitumor effects of picropodophyllin in colon carcinoma cell lines: clinical implications.
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PMID:	22159423

211.
Journal:	BMC Gastroenterol. 2012 Jan 23;12:9.
Title:	Luteolin decreases IGF-II production and downregulates insulin-like growth factor-I receptor signaling in HT-29 human colon cancer cells.
Author:	Lim, Do Young\|Cho, Han Jin\|Kim, Jongdai\|Nho, Chu Won\|Lee, Ki Won\|Park, Jung Han Yoon
PMID:	22269172

212.
Journal:	Cancer Epidemiol Biomarkers Prev. 2012 May;21(5):810-20.
Title:	Genetic variants, prediagnostic circulating levels of insulin-like growth factors, insulin, and glucose and the risk of colorectal cancer: the Multiethnic Cohort study.
Author:	Ollberding, Nicholas J\|Cheng, Iona\|Wilkens, Lynne R\|Henderson, Brian E\|Pollak, Michael N\|Kolonel, Laurence N\|Le Marchand, Loic
PMID:	22354904

213.
Journal:	J Zhejiang Univ Sci B. 2012 Mar;13(3):159-67.
Title:	Proteomic analysis of primary colon cancer-associated fibroblasts using the SELDI-ProteinChip platform.
Author:	Wang, Zhan-Huai\|Ding, Ke-Feng\|Yu, Jie-Kai\|Zhai, Xiao-Hui\|Ruan, Shu-Qin\|Wang, Shan-Wei\|Zhu, Yong-Liang\|Zheng, Shu\|Zhang, Su-Zhan
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214.
Journal:	Dis Markers. 2012;32(2):133-41.
Title:	IGF2R genetic variants, circulating IGF2 concentrations and colon cancer risk in African Americans and Whites.
Author:	Hoyo, Cathrine\|Murphy, Susan K\|Schildkraut, Joellen M\|Vidal, Adriana C\|Skaar, David\|Millikan, Robert C\|Galanko, Joseph\|Sandler, Robert S\|Jirtle, Randy\|Keku, Temitope
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215.
Journal:	Mol Med Rep. 2012 Jun;5(6):1536-40.
Title:	Loss of imprinting of IGF2 correlates with hypomethylation of the H19 differentially methylated region in the tumor tissue of colorectal cancer patients.
Author:	Tian, Fuliang\|Tang, Zhipeng\|Song, Guoqi\|Pan, Yuqin\|He, Bangshun\|Bao, Qian\|Wang, Shukui
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216.
Journal:	Cancer Causes Control. 2012 Jul;23(7):1127-38.
Title:	Genetic variants in IGF-I, IGF-II, IGFBP-3, and adiponectin genes and colon cancer risk in African Americans and Whites.
Author:	Keku, Temitope O\|Vidal, Adriana\|Oliver, Shannon\|Hoyo, Catherine\|Hall, Ingrid J\|Omofoye, Oluwaseun\|McDoom, Maya\|Worley, Kendra\|Galanko, Joseph\|Sandler, Robert S\|Millikan, Robert
PMID:	22565227

217.
Journal:	Nihon Rinsho. 2012 May;70(5):749-53.
Title:	[Epigenomic markers for tumors].
Author:	Kaneda, Atsushi
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218.
Journal:	Nature. 2012 Jul 18;487(7407):330-7.
Title:	Comprehensive molecular characterization of human colon and rectal cancer.
Author:
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219.
Journal:	Eur J Cancer. 2012 Dec;48(18):3405-13.
Title:	Insulin-like growth factor 2 messenger RNA binding protein 3 (IGF2BP3) is a marker of unfavourable prognosis in colorectal cancer.
Author:	Lochhead, Paul\|Imamura, Yu\|Morikawa, Teppei\|Kuchiba, Aya\|Yamauchi, Mai\|Liao, Xiaoyun\|Qian, Zhi Rong\|Nishihara, Reiko\|Wu, Kana\|Meyerhardt, Jeffrey A\|Fuchs, Charles S\|Ogino, Shuji
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220.
Journal:	Nature. 2012 Aug 30;488(7413):660-4.
Title:	Recurrent R-spondin fusions in colon cancer.
Author:	Seshagiri, Somasekar\|Stawiski, Eric W\|Durinck, Steffen\|Modrusan, Zora\|Storm, Elaine E\|Conboy, Caitlin B\|Chaudhuri, Subhra\|Guan, Yinghui\|Janakiraman, Vasantharajan\|Jaiswal, Bijay S\|Guillory, Joseph\|Ha, Connie\|Dijkgraaf, Gerrit J P\|Stinson, Jeremy\|Gnad, Flo
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221.
Journal:	Clin Res Hepatol Gastroenterol. 2012 Aug;36(4):345-51.
Title:	Insulin-like growth factor 2 gene methylation in peripheral blood mononuclear cells of patients with hepatitis C related cirrhosis or hepatocellular carcinoma.
Author:	Couvert, Philippe\|Carrie, Alain\|Tezenas du Montcel, Sophie\|Vaysse, Jenny\|Sutton, Angela\|Barget, Nathalie\|Trinchet, Jean-Claude\|Beaugrand, Michel\|Ganne, Nathalie\|Giral, Philippe\|Chelly, Jamel
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222.
Journal:	Mol Cancer. 2012 Nov 21;11:86.
Title:	Gene therapy for colorectal cancer by an oncolytic adenovirus that targets loss of the insulin-like growth factor 2 imprinting system.
Author:	Nie, Zhen-Lin\|Pan, Yu-Qin\|He, Bang-Shun\|Gu, Ling\|Chen, Li-Ping\|Li, Rui\|Xu, Ye-Qiong\|Gao, Tian-Yi\|Song, Guo-Qi\|Hoffman, Andrew R\|Wang, Shu-Kui\|Hu, Ji-Fan
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223.
Journal:	Int J Cancer. 2013 May 1;132(9):2209-16.
Title:	Methylation and microsatellite status and recurrence following adjuvant FOLFOX in colorectal cancer.
Author:	Han, Sae-Won\|Lee, Hyun-Jung\|Bae, Jeong Mo\|Cho, Nam-Yun\|Lee, Kyung-Hun\|Kim, Tae-Yong\|Oh, Do-Youn\|Im, Seock-Ah\|Bang, Yung-Jue\|Jeong, Seung-Yong\|Park, Kyu Joo\|Park, Jae-Gahb\|Kang, Gyeong Hoon\|Kim, Tae-You
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224.
Journal:	Biochem Genet. 2013 Feb;51(1-2):119-30.
Title:	The Igf2as transcript is exported into cytoplasm and associated with polysomes.
Author:	Duart-Garcia, Carolina\|Braunschweig, Martin H
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225.
Journal:	Gerontology. 2013;59(3):240-9.
Title:	Insulin-like growth factor 2 in development and disease: a mini-review.
Author:	Bergman, Daniel\|Halje, Matilda\|Nordin, Matilda\|Engstrom, Wilhelm
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226.
Journal:	Mol Biol Rep. 2013 May;40(5):3583-90.
Title:	Circulation insulin-like growth factor peptides and colorectal cancer risk: an updated systematic review and meta-analysis.
Author:	Chi, Feng\|Wu, Rong\|Zeng, Yue-can\|Xing, Rui\|Liu, Yang
PMID:	23269623

227.
Journal:	Scand J Immunol. 2013 Apr;77(4):255-60.
Title:	Humoral autoimmune response to IGF2 mRNA-binding protein (IMP2/p62) and its tissue-specific expression in colon cancer.
Author:	Liu, W\|Li, Z\|Xu, W\|Wang, Q\|Yang, S
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228.
Journal:	Gastroenterology. 2013 Jul;145(1):197-208.e3.
Title:	Progastrin-induced secretion of insulin-like growth factor 2 from colonic myofibroblasts stimulates colonic epithelial proliferation in mice.
Author:	Duckworth, Carrie A\|Clyde, Daniel\|Worthley, Daniel L\|Wang, Timothy C\|Varro, Andrea\|Pritchard, D Mark
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229.
Journal:	Oncol Rep. 2013 Oct;30(4):1814-22.
Title:	Gene therapy for cancer through adenovirus vectormediated expression of the Ad5 early region gene 1A based on loss of IGF2 imprinting.
Author:	Pan, Yuqin\|He, Bangshun\|Lirong, Zhang\|Nie, Zhenlin\|Chen, Liping\|Gu, Ling\|Hoffman, Andrew R\|Wang, Shukui\|Hu, Jifan
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230.
Journal:	Zhonghua Zhong Liu Za Zhi. 2013 Apr;35(4):277-81.
Title:	[Expression of molecular markers detected by immunohistochemistry and risk of lymph node metastasis in stage T1 and T2 colorecrectal cancers].
Author:	Wang, Fu-long\|Wan, De-sen\|Lu, Zhen-hai\|Fang, Yu-jing\|Li, Li-ren\|Chen, Gong\|Wu, Xiao-jun\|Ding, Pei-rong\|Kong, Ling-heng\|Lin, Jun-zhong\|Pan, Zhi-zhong
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231.
Journal:	Am J Clin Nutr. 2013 Dec;98(6):1564-74.
Title:	The association between MTHFR 677C>T genotype and folate status and genomic and gene-specific DNA methylation in the colon of individuals without colorectal neoplasia.
Author:	Hanks, Joanna\|Ayed, Iyeman\|Kukreja, Neil\|Rogers, Chris\|Harris, Jessica\|Gheorghiu, Alina\|Liu, Chee Ling\|Emery, Peter\|Pufulete, Maria
PMID:	24108782

232.
Journal:	Oncol Lett. 2013 Dec;6(6):1687-1692.
Title:	DNA methylation as an epigenetic biomarker in colorectal cancer.
Author:	Silva, Tiago Donizetti\|Vidigal, Veronica Marques\|Felipe, Aledson Vitor\|DE Lima, Jacqueline Miranda\|Neto, Ricardo Artigiani\|Saad, Sarhan Sidney\|Forones, Nora Manoukian
PMID:	24260063

233.
Journal:	Ann Surg Oncol. 2014 Apr;21(4):1166-74.
Title:	IGF2 DMR0 methylation, loss of imprinting, and patient prognosis in esophageal squamous cell carcinoma.
Author:	Murata, Asuka\|Baba, Yoshifumi\|Watanabe, Masayuki\|Shigaki, Hironobu\|Miyake, Keisuke\|Ishimoto, Takatsugu\|Iwatsuki, Masaaki\|Iwagami, Shiro\|Yoshida, Naoya\|Oki, Eiji\|Morita, Masaru\|Nakao, Mitsuyoshi\|Baba, Hideo
PMID:	24318096

234.
Journal:	Cancer Chemother Pharmacol. 2014 Mar;73(3):467-73.
Title:	Phase 1b study of safety, tolerability and efficacy of R1507, a monoclonal antibody to IGF-1R in combination with multiple standard oncology regimens in patients with advanced solid malignancies.
Author:	Mahadevan, Daruka\|Sutton, Gregory Ryan\|Arteta-Bulos, Rafael\|Bowden, Chris J\|Miller, Paul J E\|Swart, Rachel Elizabeth\|Walker, Mark S\|Haluska, Paul\|Munster, Pamela N\|Marshall, John\|Hamid, Omid\|Kurzrock, Razelle
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235.
Journal:	PLoS One. 2014 Jan 21;9(1):e86657.
Title:	Comparison of CpG island methylator phenotype (CIMP) frequency in colon cancer using different probe- and gene-specific scoring alternatives on recommended multi-gene panels.
Author:	Berg, Marianne\|Hagland, Hanne R\|Soreide, Kjetil
PMID:	24466191

236.
Journal:	J Endocrinol. 2014 Mar 17;221(1):145-55.
Title:	IGF1R blockade with ganitumab results in systemic effects on the GH-IGF axis in mice.
Author:	Moody, Gordon\|Beltran, Pedro J\|Mitchell, Petia\|Cajulis, Elaina\|Chung, Young-Ah\|Hwang, David\|Kendall, Richard\|Radinsky, Robert\|Cohen, Pinchas\|Calzone, Frank J
PMID:	24492468

237.
Journal:	Bull Exp Biol Med. 2014 Mar;156(5):684-8.
Title:	Insulin-like growth factors (IGF), IGF-binding proteins (IGFBP), and vascular endothelial growth factor (VEGF) in blood serum of patients with colorectal cancer.
Author:	Kushlinskii, N E\|Gershtein, E S\|Nikolaev, A A\|Delektorskaya, V V\|Korotkova, E A\|Dvorova, E K\|Kostyleva, O I
PMID:	24770758

238.
Journal:	Gastroenterology. 2014 Sep;147(3):637-45.
Title:	CpG island methylator phenotype is associated with response to adjuvant irinotecan-based therapy for stage III colon cancer.
Author:	Shiovitz, Stacey\|Bertagnolli, Monica M\|Renfro, Lindsay A\|Nam, Eunmi\|Foster, Nathan R\|Dzieciatkowski, Slavomir\|Luo, Yanxin\|Lao, Victoria Valinluck\|Monnat, Raymond J Jr\|Emond, Mary J\|Maizels, Nancy\|Niedzwiecki, Donna\|Goldberg, Richard M\|Saltz, Leonard B\|Ven
PMID:	24859205

239.
Journal:	Nat Med. 2014 Jul;20(7):769-77.
Title:	Oncogenic transformation of diverse gastrointestinal tissues in primary organoid culture.
Author:	Li, Xingnan\|Nadauld, Lincoln\|Ootani, Akifumi\|Corney, David C\|Pai, Reetesh K\|Gevaert, Olivier\|Cantrell, Michael A\|Rack, Paul G\|Neal, James T\|Chan, Carol W-M\|Yeung, Trevor\|Gong, Xue\|Yuan, Jenny\|Wilhelmy, Julie\|Robine, Sylvie\|Attardi, Laura D\|Plevritis, Sylv
PMID:	24859528

240.
Journal:	World J Gastroenterol. 2014 Aug 7;20(29):10050-61.
Title:	IGF2 differentially methylated region hypomethylation in relation to pathological and molecular features of serrated lesions.
Author:	Naito, Takafumi\|Nosho, Katsuhiko\|Ito, Miki\|Igarashi, Hisayoshi\|Mitsuhashi, Kei\|Yoshii, Shinji\|Aoki, Hironori\|Nomura, Masafumi\|Sukawa, Yasutaka\|Yamamoto, Eiichiro\|Adachi, Yasushi\|Takahashi, Hiroaki\|Hosokawa, Masao\|Fujita, Masahiro\|Takenouchi, Toshinao\|Maru
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241.
Journal:	Br J Cancer. 2014 Nov 11;111(10):1932-44.
Title:	A parallel-arm phase I trial of the humanised anti-IGF-1R antibody dalotuzumab in combination with the AKT inhibitor MK-2206, the mTOR inhibitor ridaforolimus, or the NOTCH inhibitor MK-0752, in patients with advanced solid tumours.
Author:	Brana, I\|Berger, R\|Golan, T\|Haluska, P\|Edenfield, J\|Fiorica, J\|Stephenson, J\|Martin, L P\|Westin, S\|Hanjani, P\|Jones, M B\|Almhanna, K\|Wenham, R M\|Sullivan, D M\|Dalton, W S\|Gunchenko, A\|Cheng, J D\|Siu, L L\|Gray, J E
PMID:	25290091

242.
Journal:	J Cancer Prev. 2014 Sep;19(3):161-9.
Title:	Kaempferol Downregulates Insulin-like Growth Factor-I Receptor and ErbB3 Signaling in HT-29 Human Colon Cancer Cells.
Author:	Lee, Hyun Sook\|Cho, Han Jin\|Kwon, Gyoo Taik\|Park, Jung Han Yoon
PMID:	25337585

243.
Journal:	Am J Clin Nutr. 2014 Dec;100(6):1479-88.
Title:	Alcohol, one-carbon nutrient intake, and risk of colorectal cancer according to tumor methylation level of IGF2 differentially methylated region.
Author:	Nishihara, Reiko\|Wang, Molin\|Qian, Zhi Rong\|Baba, Yoshifumi\|Yamauchi, Mai\|Mima, Kosuke\|Sukawa, Yasutaka\|Kim, Sun A\|Inamura, Kentaro\|Zhang, Xuehong\|Wu, Kana\|Giovannucci, Edward L\|Chan, Andrew T\|Fuchs, Charles S\|Ogino, Shuji\|Schernhammer, Eva S
PMID:	25411283

244.
Journal:	PLoS One. 2014 Dec 4;9(12):e114420.
Title:	MiR-143 and MiR-145 regulate IGF1R to suppress cell proliferation in colorectal cancer.
Author:	Su, Jiaojiao\|Liang, Hongwei\|Yao, Weiyan\|Wang, Nan\|Zhang, Suyang\|Yan, Xin\|Feng, Hui\|Pang, Wenjing\|Wang, Yanbo\|Wang, Xueliang\|Fu, Zhen\|Liu, Yanqing\|Zhao, Chihao\|Zhang, Junfeng\|Zhang, Chen-Yu\|Zen, Ke\|Chen, Xi\|Wang, Yalei
PMID:	25474488

245.
Journal:	Gut Liver. 2015 Mar;9(2):202-7.
Title:	The role of the CpG island methylator phenotype on survival outcome in colon cancer.
Author:	Kang, Ki Joo\|Min, Byung Hoon\|Ryu, Kyung Ju\|Kim, Kyoung Mee\|Chang, Dong Kyung\|Kim, Jae J\|Rhee, Jong Chul\|Kim, Young Ho
PMID:	25167802

246.
Journal:	Biochim Biophys Acta. 2015 Jan;1855(1):104-21.
Title:	Portrait of the PI3K/AKT pathway in colorectal cancer.
Author:	Danielsen, Stine Aske\|Eide, Peter Wold\|Nesbakken, Arild\|Guren, Tormod\|Leithe, Edward\|Lothe, Ragnhild A
PMID:	25450577

247.
Journal:	Clin J Gastroenterol. 2015 Feb;8(1):35-40.
Title:	Insulin-like growth factor II-producing metastatic colon cancer with recurrent hypoglycemia.
Author:	Teramae, Satoshi\|Miyamoto, Hiroshi\|Muguruma, Naoki\|Okada, Yasuyuki\|Goji, Takahiro\|Kitamura, Shinji\|Kimura, Tetsuo\|Kimura, Masako\|Bando, Yoshimi\|Takayama, Tetsuji
PMID:	25605315

248.
Journal:	Int J Oncol. 2015 Apr;46(4):1759-67.
Title:	Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin-like growth factor 2 imprinting.
Author:	Sun, Huiling\|Pan, Yuqin\|He, Bangshun\|Deng, Qiwen\|Li, Rui\|Xu, Yeqiong\|Chen, Jie\|Gao, Tianyi\|Ying, Houqun\|Wang, Feng\|Liu, Xian\|Wang, Shukui
PMID:	25625919

249.
Journal:	Sci Transl Med. 2015 Jan 28;7(272):272ra12.
Title:	IGF2 is an actionable target that identifies a distinct subpopulation of colorectal cancer patients with marginal response to anti-EGFR therapies.
Author:	Zanella, Eugenia R\|Galimi, Francesco\|Sassi, Francesco\|Migliardi, Giorgia\|Cottino, Francesca\|Leto, Simonetta M\|Lupo, Barbara\|Erriquez, Jessica\|Isella, Claudio\|Comoglio, Paolo M\|Medico, Enzo\|Tejpar, Sabine\|Budinska, Eva\|Trusolino, Livio\|Bertotti, Andrea
PMID:	25632036

250.
Journal:	Digestion. 2015;91(1):57-63.
Title:	Clinicopathological and molecular characteristics of serrated lesions in Japanese elderly patients.
Author:	Nosho, Katsuhiko\|Igarashi, Hisayoshi\|Ito, Miki\|Mitsuhashi, Kei\|Kurihara, Hiroyoshi\|Kanno, Shinichi\|Yoshii, Shinji\|Mikami, Masashi\|Takahashi, Hiroaki\|Kusumi, Takaya\|Hosokawa, Masao\|Sukawa, Yasutaka\|Adachi, Yasushi\|Hasegawa, Tadashi\|Okita, Kenji\|Hirata, Koi
PMID:	25632919

251.
Journal:	Cancer Res. 2015 Apr 15;75(8):1560-6.
Title:	Evaluating patient-derived colorectal cancer xenografts as preclinical models by comparison with patient clinical data.
Author:	Nunes, Manoel\|Vrignaud, Patricia\|Vacher, Sophie\|Richon, Sophie\|Lievre, Astrid\|Cacheux, Wulfran\|Weiswald, Louis-Bastien\|Massonnet, Gerald\|Chateau-Joubert, Sophie\|Nicolas, Andre\|Dib, Colette\|Zhang, Weidong\|Watters, James\|Bergstrom, Donald\|Roman-Roman, Sergi
PMID:	25712343

252.
Journal:	Int J Clin Exp Pathol. 2015 Feb 1;8(2):1920-8. eCollection 2015.
Title:	Nuclear maspin expression correlates with the CpG island methylator phenotype and tumor aggressiveness in colorectal cancer.
Author:	Kim, Jung Ho\|Cho, Nam-Yun\|Bae, Jeong Mo\|Kim, Kyung-Ju\|Rhee, Ye-Young\|Lee, Hye Seung\|Kang, Gyeong Hoon
PMID:	25973084

253.
Journal:	Eksp Klin Gastroenterol. 2015;(2):40-5.
Title:	[Changes in markers of proliferation, neoangiogenesis and plasminogen activation system in rectal cancer tissue].
Author:	Kit, O I\|Frantsiyants, E M\|Nikipelova, E A\|Komarova, E F\|Kozlova, L S\|Tavaryan, I S\|Averkin, M A\|Cheryarina, N D
PMID:	25993872

254.
Journal:	Proc Natl Acad Sci U S A. 2015 Jun 23;112(25):7743-8.
Title:	Transcriptional modulator ZBED6 affects cell cycle and growth of human colorectal cancer cells.
Author:	Akhtar Ali, Muhammad\|Younis, Shady\|Wallerman, Ola\|Gupta, Rajesh\|Andersson, Leif\|Sjoblom, Tobias
PMID:	26056301

255.
Journal:	Oncoscience. 2015 Jul 1;2(6):607-14.
Title:	Expression of the cancer testis antigen IGF2BP3 in colorectal cancers; IGF2BP3 holds promise as a specific immunotherapy target.
Author:	Shantha Kumara, Hmc\|Kirchoff, Daniel\|Caballero, Otavia L\|Su, Tao\|Ahmed, Aqeel\|Herath, Sonali Ac\|Njoh, Linda\|Cekic, Vesna\|Simpson, Andrew J\|Cordon-Cardo, Carlos\|Whelan, Richard L
PMID:	26244168

256.
Journal:	Int J Oncol. 2015 Nov;47(5):1881-9.
Title:	Gene therapy for colorectal cancer by adenovirus-mediated siRNA targeting CD147 based on loss of the IGF2 imprinting system.
Author:	Pan, Yuqin\|He, Bangshun\|Chen, Jie\|Sun, Huiling\|Deng, Qiwen\|Wang, Feng\|Ying, Houqun\|Liu, Xian\|Lin, Kang\|Peng, Hongxin\|Xie, Hongguang\|Wang, Shukui
PMID:	26397886

257.
Journal:	Exp Cell Res. 2015 Nov 1;338(2):214-21.
Title:	Restoration of IGF2 imprinting by polycomb repressive complex 2 docking factor SUZ12 in colon cancer cells.
Author:	Wang, Haibo\|Ge, Shengfang\|Qian, Guanxiang\|Li, Wei\|Cui, Jiuwei\|Wang, Guanjun\|Hoffman, Andrew R\|Hu, Ji-Fan
PMID:	26407907

258.
Journal:	Int J Mol Sci. 2015 Oct 2;16(10):23615-29.
Title:	Insulin-Like Growth Factor-2 Is Induced Following 5-Aminolevulinic Acid-Mediated Photodynamic Therapy in SW620 Human Colon Cancer Cell Line.
Author:	Wozniak, Marta\|Dus-Szachniewicz, Kamila\|Ziolkowski, Piotr
PMID:	26445041

259.
Journal:	Front Oncol. 2015 Oct 15;5:230.
Title:	The Insulin/IGF System in Colorectal Cancer Development and Resistance to Therapy.
Author:	Vigneri, Paolo Giovanni\|Tirro, Elena\|Pennisi, Maria Stella\|Massimino, Michele\|Stella, Stefania\|Romano, Chiara\|Manzella, Livia
PMID:	26528439

260.
Journal:	Clin Colorectal Cancer. 2016 Jun;15(2):164-9.
Title:	Evaluation of CpG Island Methylator Phenotype as a Biomarker in Colorectal Cancer Treated With Adjuvant Oxaliplatin.
Author:	Cohen, Stacey A\|Wu, Chen\|Yu, Ming\|Gourgioti, Georgia\|Wirtz, Ralph\|Raptou, Georgia\|Gkakou, Chryssa\|Kotoula, Vassiliki\|Pentheroudakis, George\|Papaxoinis, George\|Karavasilis, Vasilios\|Pectasides, Dimitrios\|Kalogeras, Konstantine T\|Fountzilas, George\|Grady, W
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261.
Journal:	BMC Syst Biol. 2016 Feb 9;10:15.
Title:	Quantitative analysis of insulin-like growth factor 2 receptor and insulin-like growth factor binding proteins to identify control mechanisms for insulin-like growth factor 1 receptor phosphorylation.
Author:	Tian, Dan\|Mitchell, Isaiah\|Kreeger, Pamela K
PMID:	26861122

262.
Journal:	J Gastroenterol. 2016 Oct;51(10):971-84.
Title:	Carcinoma of the colon and rectum with deregulation of insulin-like growth factor 2 signaling: clinical and molecular implications.
Author:	Belharazem, Djeda\|Magdeburg, Julia\|Berton, Ann-Kristin\|Beissbarth, Li\|Sauer, Christian\|Sticht, Carsten\|Marx, Alexander\|Hofheinz, Ralf\|Post, Stefan\|Kienle, Peter\|Strobel, Philipp
PMID:	26984550

263.
Journal:	FEBS Lett. 2016 Jun;590(11):1641-50.
Title:	IGF2BP2 promotes colorectal cancer cell proliferation and survival through interfering with RAF-1 degradation by miR-195.
Author:	Ye, Song\|Song, Wei\|Xu, Xiaogang\|Zhao, Xinyi\|Yang, Liu
PMID:	27153315

264.
Journal:	Genes Chromosomes Cancer. 2016 Nov;55(11):821-33.
Title:	Copy number changes of clinically actionable genes in melanoma, non-small cell lung cancer and colorectal cancer-A survey across 822 routine diagnostic cases.
Author:	Pfarr, Nicole\|Penzel, Roland\|Klauschen, Frederick\|Heim, Daniel\|Brandt, Regine\|Kazdal, Daniel\|Jesinghaus, Moritz\|Herpel, Esther\|Schirmacher, Peter\|Warth, Arne\|Weichert, Wilko\|Endris, Volker\|Stenzinger, Albrecht
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265.
Journal:	Oncotarget. 2016 Aug 9;7(32):51349-51364.
Title:	Loss of insulin-like growth factor II imprinting is a hallmark associated with enhanced chemo/radiotherapy resistance in cancer stem cells.
Author:	Zhao, Xin\|Liu, Xiaoliang\|Wang, Guanjun\|Wen, Xue\|Zhang, Xiaoying\|Hoffman, Andrew R\|Li, Wei\|Hu, Ji-Fan\|Cui, Jiuwei
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266.
Journal:	Tumour Biol. 2016 Sep;37(9):12485-12495.
Title:	IGF2 knockdown in two colorectal cancer cell lines decreases survival, adhesion and modulates survival-associated genes.
Author:	Rogers, Michael A\|Kalter, Verena\|Strowitzki, Moritz\|Schneider, Martin\|Lichter, Peter
PMID:	27337954

267.
Journal:	Oncotarget. 2016 Jul 26;7(30):48456-48466.
Title:	IGF2-derived miR-483 mediated oncofunction by suppressing DLC-1 and associated with colorectal cancer.
Author:	Cui, Hengmi\|Liu, Yuan\|Jiang, Jingrui\|Liu, Yangyang\|Yang, Zhe\|Wu, Shaogen\|Cao, Wangsen\|Cui, Isabelle H\|Yu, Chenggong
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268.
Journal:	Oncotarget. 2016 Aug 2;7(31):50490-50506.
Title:	Myotubularin-related protein 7 inhibits insulin signaling in colorectal cancer.
Author:	Weidner, Philip\|Sohn, Michaela\|Gutting, Tobias\|Friedrich, Teresa\|Gaiser, Timo\|Magdeburg, Julia\|Kienle, Peter\|Ruh, Hermelindis\|Hopf, Carsten\|Behrens, Hans-Michael\|Rocken, Christoph\|Hanoch, Tamar\|Seger, Rony\|Ebert, Matthias P A\|Burgermeister, Elke
PMID:	27409167

269.
Journal:	Ginekol Pol. 2016;87(8):598-604.
Title:	Does IGF-1 play a role in the biology of endometrial cancer?
Author:	Majchrzak-Baczmanska, Dominika\|Malinowski, Andrzej
PMID:	27629137

270.
Journal:	Oncogene. 2017 Feb 9;36(6):797-806.
Title:	Overproduction of IGF-2 drives a subset of colorectal cancer cells, which specifically respond to an anti-IGF therapeutic antibody and combination therapies.
Author:	Zhong, H\|Fazenbaker, C\|Chen, C\|Breen, S\|Huang, J\|Yao, X\|Ren, P\|Yao, Y\|Herbst, R\|Hollingsworth, R E
PMID:	27399333

271.
Journal:	Nat Genet. 2017 Jan;49(1):65-74.
Title:	Pan-cancer analysis of somatic copy-number alterations implicates IRS4 and IGF2 in enhancer hijacking.
Author:	Weischenfeldt, Joachim\|Dubash, Taronish\|Drainas, Alexandros P\|Mardin, Balca R\|Chen, Yuanyuan\|Stutz, Adrian M\|Waszak, Sebastian M\|Bosco, Graziella\|Halvorsen, Ann Rita\|Raeder, Benjamin\|Efthymiopoulos, Theocharis\|Erkek, Serap\|Siegl, Christine\|Brenner, Herman
PMID:	27869826

272.
Journal:	Peptides. 2017 May;91:49-57.
Title:	Glucagon-like petide-2 acts on colon cancer myofibroblasts to stimulate proliferation, migration and invasion of both myofibroblasts and cancer cells via the IGF pathway.
Author:	Shawe-Taylor, Marianne\|Kumar, J Dinesh\|Holden, Whitney\|Dodd, Steven\|Varga, Akos\|Giger, Olivier\|Varro, Andrea\|Dockray, Graham J
PMID:	28363795

273.
Journal:	Clin Epigenetics. 2017 May 2;9:46.
Title:	The CpG island methylator phenotype is concordant between primary colorectal carcinoma and matched distant metastases.
Author:	Cohen, Stacey A\|Yu, Ming\|Baker, Kelsey\|Redman, Mary\|Wu, Chen\|Heinzerling, Tai J\|Wirtz, Ralph M\|Charalambous, Elpida\|Pentheroudakis, George\|Kotoula, Vassiliki\|Kalogeras, Konstantine T\|Fountzilas, George\|Grady, William M
PMID:	28469732

274.
Journal:	Oncol Lett. 2017 May;13(5):3958-3966.
Title:	Clinicopathological significance and impact on outcomes of the gene expression levels of IGF-1, IGF-2 and IGF-1R, IGFBP-3 in patients with colorectal cancer: Overexpression of the IGFBP-3 gene is an effective predictor of outcomes in patients with colorec
Author:	Yamamoto, Naoto\|Oshima, Takashi\|Yoshihara, Kazue\|Aoyama, Toru\|Hayashi, Tsutomu\|Yamada, Takanobu\|Sato, Tsutomu\|Shiozawa, Manabu\|Yoshikawa, Takaki\|Morinaga, Soichiro\|Rino, Yasushi\|Kunisaki, Chikara\|Tanaka, Katsuaki\|Akaike, Makoto\|Imada, Toshio\|Masuda, Munet
PMID:	28521493

275.
Journal:	Oncogene. 2017 Sep 21;36(38):5341-5355.
Title:	Stromal-derived IGF2 promotes colon cancer progression via paracrine and autocrine mechanisms.
Author:	Unger, C\|Kramer, N\|Unterleuthner, D\|Scherzer, M\|Burian, A\|Rudisch, A\|Stadler, M\|Schlederer, M\|Lenhardt, D\|Riedl, A\|Walter, S\|Wernitznig, A\|Kenner, L\|Hengstschlager, M\|Schuler, J\|Sommergruber, W\|Dolznig, H
PMID:	28534511

276.
Journal:	Int J Cancer. 2017 Sep 1;141(5):967-976.
Title:	CpG island methylator phenotype identifies high risk patients among microsatellite stable BRAF mutated colorectal cancers.
Author:	Vedeld, Hege Marie\|Merok, Marianne\|Jeanmougin, Marine\|Danielsen, Stine A\|Honne, Hilde\|Presthus, Gro Kummeneje\|Svindland, Aud\|Sjo, Ole H\|Hektoen, Merete\|Eknaes, Mette\|Nesbakken, Arild\|Lothe, Ragnhild A\|Lind, Guro E
PMID:	28542846

277.
Journal:	Nat Commun. 2017 May 31;8:15107.
Title:	Selective analysis of cancer-cell intrinsic transcriptional traits defines novel clinically relevant subtypes of colorectal cancer.
Author:	Isella, Claudio\|Brundu, Francesco\|Bellomo, Sara E\|Galimi, Francesco\|Zanella, Eugenia\|Porporato, Roberta\|Petti, Consalvo\|Fiori, Alessandro\|Orzan, Francesca\|Senetta, Rebecca\|Boccaccio, Carla\|Ficarra, Elisa\|Marchionni, Luigi\|Trusolino, Livio\|Medico, Enzo\|Ber
PMID:	28561063

278.
Journal:	Mol Cancer Ther. 2017 Oct;16(10):2223-2233.
Title:	The IGF1R/INSR Inhibitor BI 885578 Selectively Inhibits Growth of IGF2-Overexpressing Colorectal Cancer Tumors and Potentiates the Efficacy of Anti-VEGF Therapy.
Author:	Sanderson, Michael P\|Hofmann, Marco H\|Garin-Chesa, Pilar\|Schweifer, Norbert\|Wernitznig, Andreas\|Fischer, Stefan\|Jeschko, Astrid\|Meyer, Reiner\|Moll, Jurgen\|Pecina, Thomas\|Arnhof, Heribert\|Weyer-Czernilofsky, Ulrike\|Zahn, Stephan K\|Adolf, Gunther R\|Kraut, N
PMID:	28729397

279.
Journal:	Hum Pathol. 2018 Apr;74:54-63.
Title:	Genomic heterogeneity in primary colorectal carcinomas and their metastases: born bad or brought up a villain?
Author:	Huhns, Maja\|Krohn, Saskia\|Murua Escobar, Hugo\|Prall, Friedrich
PMID:	29307628

280.
Journal:	Cancer Cell Int. 2018 Jan 23;18:11.
Title:	Exosomal lncRNA 91H is associated with poor development in colorectal cancer by modifying HNRNPK expression.
Author:	Gao, Tianyi\|Liu, Xiangxiang\|He, Bangshun\|Nie, Zhenlin\|Zhu, Chengbin\|Zhang, Pei\|Wang, Shukui
PMID:	29410604

281.
Journal:	Sci Rep. 2018 Feb 16;8(1):3161.
Title:	Molecular characterization of colorectal adenomas with and without malignancy reveals distinguishing genome, transcriptome and methylome alterations.
Author:	Druliner, Brooke R\|Wang, Panwen\|Bae, Taejeong\|Baheti, Saurabh\|Slettedahl, Seth\|Mahoney, Douglas\|Vasmatzis, Nikolaos\|Xu, Hang\|Kim, Minsoo\|Bockol, Matthew\|O'Brien, Daniel\|Grill, Diane\|Warner, Nathaniel\|Munoz-Gomez, Miguel\|Kossick, Kimberlee\|Johnson, Ruth\|Mo
PMID:	29453410

282.
Journal:	Clin Drug Investig. 2018 Jun;38(6):553-562.
Title:	First-Line Cetuximab Monotherapy in KRAS/NRAS/BRAF Mutation-Negative Colorectal Cancer Patients.
Author:	Moiseyenko, Vladimir M\|Moiseyenko, Fedor V\|Yanus, Grigoriy A\|Kuligina, Ekatherina Sh\|Sokolenko, Anna P\|Bizin, Ilya V\|Kudriavtsev, Alexey A\|Aleksakhina, Svetlana N\|Volkov, Nikita M\|Chubenko, Vyacheslav A\|Kozyreva, Kseniya S\|Kramchaninov, Mikhail M\|Zhuravle
PMID:	29470838

283.
Journal:	J Transl Med. 2018 Feb 27;16(1):45.
Title:	A novel DNA methylation panel accurately detects colorectal cancer independently of molecular pathway.
Author:	Freitas, Micaela\|Ferreira, Fabio\|Carvalho, Sonia\|Silva, Fernanda\|Lopes, Paula\|Antunes, Luis\|Salta, Sofia\|Diniz, Francisca\|Santos, Lucio Lara\|Videira, Jose Flavio\|Henrique, Rui\|Jeronimo, Carmen
PMID:	29486770

284.
Journal:	J Genet Genomics. 2018 Apr 20;45(4):205-214.
Title:	DNA methylation-mediated repression of miR-181a/135a/302c expression promotes the microsatellite-unstable colorectal cancer development and 5-FU resistance via targeting PLAG1.
Author:	Shi, Lu\|Li, Xiang\|Wu, Zhiqiang\|Li, Xiaolei\|Nie, Jing\|Guo, Mingzhou\|Mei, Qian\|Han, Weidong
PMID:	29735329

285.
Journal:	Oncogene. 2018 Jun 12. pii: 10.1038/s41388-018-0362-5.
Title:	beta-catenin/TCF activity regulates IGF-1R tyrosine kinase inhibitor sensitivity in colon cancer.
Author:	Lee, Hani\|Kim, Nayoung\|Yoo, Young Ji\|Kim, Hyejin\|Jeong, Euna\|Choi, SeokGyeong\|Moon, Sung Un\|Oh, Seung Hyun\|Mills, Gordon B\|Yoon, Sukjoon\|Kim, Woo-Young
PMID:	29895971

286.
Journal:	Clin Cancer Res. 2018 Oct 1;24(19):4745-4753.
Title:	Prognostic Value of Methylator Phenotype in Stage III Colon Cancer Treated with Oxaliplatin-based Adjuvant Chemotherapy.
Author:	Gallois, Claire\|Taieb, Julien\|Le Corre, Delphine\|Le Malicot, Karine\|Tabernero, Josep\|Mulot, Claire\|Seitz, Jean-Francois\|Aparicio, Thomas\|Folprecht, Gunnar\|Lepage, Come\|Mini, Enrico\|Van Laethem, Jean-Luc\|Emile, Jean-Francois\|Laurent-Puig, Pierre
PMID:	29921730

287.
Journal:	Biomed Pharmacother. 2018 Oct;106:763-769.
Title:	MiR-185 enhances radiosensitivity of colorectal cancer cells by targeting IGF1R and IGF2.
Author:	Afshar, Saeid\|Najafi, Rezvan\|Sedighi Pashaki, Abdolazim\|Sharifi, Mohammadreza\|Nikzad, Safoora\|Gholami, Mohammad Hadi\|Khoshghadam, Alireza\|Amini, Razieh\|Karimi, Jamshid\|Saidijam, Massoud
PMID:	29990869

288.
Journal:	Cell Death Dis. 2018 Oct 10;9(10):1037.
Title:	DNA-methylation-mediated silencing of miR-486-5p promotes colorectal cancer proliferation and migration through activation of PLAGL2/IGF2/beta-catenin signal pathways.
Author:	Liu, Xiangxiang\|Chen, Xiaoxiang\|Zeng, Kaixuan\|Xu, Mu\|He, Bangshun\|Pan, Yuqin\|Sun, Huiling\|Pan, Bei\|Xu, Xueni\|Xu, Tao\|Hu, Xiuxiu\|Wang, Shukui
PMID:	30305607