Primary Site >> Liver Cancer
Gene >> IGF1R
| 1. | |||||||||||
| Journal: | Mol Pathol. 2001 Jun;54(3):138-44. | ||||||||||
| Title: | The IGF axis and hepatocarcinogenesis. | ||||||||||
| Author: | Scharf, J G|Dombrowski, F|Ramadori, G | ||||||||||
| PMID: | 11376124 | ||||||||||
| 2. | |||||||||||
| Journal: | Tissue Antigens. 2014 Sep;84(3):264-70. | ||||||||||
| Title: | Association of IGF1R polymorphisms with the development of HBV-related hepatocellular carcinoma. | ||||||||||
| Author: | Xie, H-Y|Xing, C-Y|Wei, B-J|Xu, X|Wu, J|Chen, L-M|Cao, G-Q|Chen, H|Chen, K-J|Yin, S-Y|Wu, L-M|Zhou, L|Zheng, S-S | ||||||||||
| PMID: | 24758241 | ||||||||||
| 3. | |||||||||||
| Journal: | PLoS One. 2014 Sep 17;9(9):e107149. | ||||||||||
| Title: | Fatty acid esters of phloridzin induce apoptosis of human liver cancer cells through altered gene expression. | ||||||||||
| Author: | Nair, Sandhya V G|Ziaullah|Rupasinghe, H P Vasantha | ||||||||||
| PMID: | 25229655 | ||||||||||
| 4. | |||||||||||
| Journal: | Oncol Rep. 2015 Sep;34(3):1121-8. | ||||||||||
| Title: | Knockdown of SOX18 inhibits the proliferation, migration and invasion of hepatocellular carcinoma cells. | ||||||||||
| Author: | Wang, Guiming|Wei, Zhigang|Jia, Hongyan|Zhao, Wenbo|Yang, Gaochao|Zhao, Haoliang | ||||||||||
| PMID: | 26151573 | ||||||||||
| 5. | |||||||||||
| Journal: | FEBS Lett. 2015 Aug 4;589(17):2257-65. | ||||||||||
| Title: | miR-1275: A single microRNA that targets the three IGF2-mRNA-binding proteins hindering tumor growth in hepatocellular carcinoma. | ||||||||||
| Author: | Fawzy, Injie Omar|Hamza, Mohammed Tarif|Hosny, Karim Adel|Esmat, Gamal|El Tayebi, Hend Mohamed|Abdelaziz, Ahmed Ihab | ||||||||||
| PMID: | 26160756 | ||||||||||
| 6. | |||||||||||
| Journal: | Eur Rev Med Pharmacol Sci. 2016 Dec;20(24):5098-5106. | ||||||||||
| Title: | Bioinformatic identification of IGF1 as a hub gene in hepatocellular carcinoma (HCC) and in-vitro analysis of the chemosensitizing effect of miR-379 via suppressing the IGF1/IGF1R signaling pathway. | ||||||||||
| Author: | Huang, D-J|Huang, J-Z|Yang, J|Li, Y-H|Luo, Y-C|He, H-Y|Huang, H-J | ||||||||||
| PMID: | 28051262 | ||||||||||
| 7. | |||||||||||
| Journal: | Oncotarget. 2016 Nov 8;7(45):72908-72922. | ||||||||||
| Title: | Genomic characterization of liver metastases from colorectal cancer patients. | ||||||||||
| Author: | Sayagues, Jose Maria|Corchete, Luis Antonio|Gutierrez, Maria Laura|Sarasquete, Maria Eugenia|Del Mar Abad, Maria|Bengoechea, Oscar|Ferminan, Encarna|Anduaga, Maria Fernanda|Del Carmen, Sofia|Iglesias, Manuel|Esteban, Carmen|Angoso, Maria|Alcazar, Jose Ant | ||||||||||
| PMID: | 27662660 | ||||||||||
| 8. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2016 Sep 16;478(2):964-9. | ||||||||||
| Title: | Insulin-like growth factor-binding protein-3 inhibits IGF-1-induced proliferation of human hepatocellular carcinoma cells by controlling bFGF and PDGF autocrine/paracrine loops. | ||||||||||
| Author: | Ma, Yang|Han, Chen-Chen|Li, Yifan|Wang, Yang|Wei, Wei | ||||||||||
| PMID: | 27521890 | ||||||||||
| 9. | |||||||||||
| Journal: | Growth Factors. 2016 Feb;34(1-2):42-50. | ||||||||||
| Title: | Abrogating the interplay between IGF2BP1, 2 and 3 and IGF1R by let-7i arrests hepatocellular carcinoma growth. | ||||||||||
| Author: | Fawzy, Injie Omar|Hamza, Mohammed Tarif|Hosny, Karim Adel|Esmat, Gamal|Abdelaziz, Ahmed Ihab | ||||||||||
| PMID: | 27126374 | ||||||||||
| 10. | |||||||||||
| Journal: | Oncol Rep. 2016 May;35(5):3068-74. | ||||||||||
| Title: | GRK2 overexpression inhibits IGF1-induced proliferation and migration of human hepatocellular carcinoma cells by downregulating EGR1. | ||||||||||
| Author: | Ma, Yang|Han, Chen-Chen|Huang, Qiong|Sun, Wu-Yi|Wei, Wei | ||||||||||
| PMID: | 26936374 | ||||||||||
| 11. | |||||||||||
| Journal: | Oncotarget. 2016 Mar 1;7(9):9718-31. | ||||||||||
| Title: | The dual targeting of insulin and insulin-like growth factor 1 receptor enhances the mTOR inhibitor-mediated antitumor efficacy in hepatocellular carcinoma. | ||||||||||
| Author: | Pivonello, Claudia|Negri, Mariarosaria|De Martino, Maria Cristina|Napolitano, Maria|de Angelis, Cristina|Provvisiero, Donatella Paola|Cuomo, Gaia|Auriemma, Renata Simona|Simeoli, Chiara|Izzo, Francesco|Colao, Annamaria|Hofland, Leo J|Pivonello, Rosario | ||||||||||
| PMID: | 26756219 | ||||||||||
| 12. | |||||||||||
| Journal: | J Clin Pathol. 2016 Feb;69(2):102-8. | ||||||||||
| Title: | Facing the enigma of the vascular network in hepatocellular carcinomas in cirrhotic and non-cirrhotic livers. | ||||||||||
| Author: | Vasuri, Francesco|Fittipaldi, Silvia|Giunchi, Francesca|Monica, Melissa|Ravaioli, Matteo|Degiovanni, Alessio|Bonora, Sonia|Golfieri, Rita|Bolondi, Luigi|Grigioni, Walter F|Pasquinelli, Gianandrea|D'Errico-Grigioni, Antonia | ||||||||||
| PMID: | 26243063 | ||||||||||
| 13. | |||||||||||
| Journal: | Mol Carcinog. 2017 Apr;56(4):1302-1311. | ||||||||||
| Title: | TGFbeta signaling confers sorafenib resistance via induction of multiple RTKs in hepatocellular carcinoma cells. | ||||||||||
| Author: | Ungerleider, Nathan|Han, Chang|Zhang, Jinqiang|Yao, Lu|Wu, Tong | ||||||||||
| PMID: | 27862334 | ||||||||||
| 14. | |||||||||||
| Journal: | Basic Clin Pharmacol Toxicol. 2017 Oct;121(4):334-341. | ||||||||||
| Title: | Cis-Nerolidol Induces Endoplasmic Reticulum Stress and Cell Death in Human Hepatocellular Carcinoma Cells through Extensive CYP2C19 and CYP1A2 Oxidation. | ||||||||||
| Author: | Biazi, Bruna Isabela|Zanetti, Thalita Alves|Baranoski, Adrivanio|Corveloni, Amanda Cristina|Mantovani, Mario Sergio | ||||||||||
| PMID: | 28256105 | ||||||||||
| 15. | |||||||||||
| Journal: | Oncotarget. 2017 Jul 18;8(29):47984-47997. | ||||||||||
| Title: | Co-targeting of IGF1R/mTOR pathway by miR-497 and miR-99a impairs hepatocellular carcinoma development. | ||||||||||
| Author: | Cheng, Henghui|Xue, Jin|Yang, Shouhua|Chen, Yaobin|Wang, Yu|Zhu, Yuanli|Wang, Xiaoyan|Kuang, Dong|Ruan, Qiurong|Duan, Yaqi|Wang, Guoping | ||||||||||
| PMID: | 28624790 | ||||||||||
| 16. | |||||||||||
| Journal: | Mol Med Rep. 2017 Aug;16(2):2241-2246. | ||||||||||
| Title: | MicroRNA-187 inhibits tumor growth and metastasis via targeting of IGF-1R in hepatocellular carcinoma. | ||||||||||
| Author: | Han, Xinqiang|Wang, Xuemin|Zhao, Baolei|Chen, Gang|Sheng, Yuguo|Wang, Wenming|Teng, Mujian | ||||||||||
| PMID: | 28627639 | ||||||||||
| 17. | |||||||||||
| Journal: | Mol Cancer Ther. 2017 Oct;16(10):2223-2233. | ||||||||||
| Title: | The IGF1R/INSR Inhibitor BI 885578 Selectively Inhibits Growth of IGF2-Overexpressing Colorectal Cancer Tumors and Potentiates the Efficacy of Anti-VEGF Therapy. | ||||||||||
| Author: | Sanderson, Michael P|Hofmann, Marco H|Garin-Chesa, Pilar|Schweifer, Norbert|Wernitznig, Andreas|Fischer, Stefan|Jeschko, Astrid|Meyer, Reiner|Moll, Jurgen|Pecina, Thomas|Arnhof, Heribert|Weyer-Czernilofsky, Ulrike|Zahn, Stephan K|Adolf, Gunther R|Kraut, N | ||||||||||
| PMID: | 28729397 | ||||||||||
| 18. | |||||||||||
| Journal: | Oncotarget. 2017 Sep 21;8(60):101520-101534. | ||||||||||
| Title: | Therapeutic potential of an anti-angiogenic multimodal biomimetic peptide in hepatocellular carcinoma. | ||||||||||
| Author: | Barbhuiya, Mustafa A|Mirando, Adam C|Simons, Brian W|Lemtiri-Chlieh, Ghali|Green, Jordan J|Popel, Aleksander S|Pandey, Niranjan B|Tran, Phuoc T | ||||||||||
| PMID: | 29254183 | ||||||||||
| 19. | |||||||||||
| Journal: | Biochim Biophys Acta Gene Regul Mech. 2018 Feb;1861(2):117-124. | ||||||||||
| Title: | Epigenetic alterations contribute to promoter activity of imprinting gene IGF2. | ||||||||||
| Author: | Zheng, Qi-Fan|Xu, Bin|Wang, Hui-Min|Ding, Li-Hong|Liu, Jin-Yang|Zhu, Ling-Yu|Qiu, Huan|Zhang, Li|Ni, Guang-Yi|Ye, Jing|Gao, Shu-Bin|Jin, Guang-Hui | ||||||||||
| PMID: | 29413895 | ||||||||||
| 20. | |||||||||||
| Journal: | Exp Ther Med. 2018 Jan;15(1):1150-1158. | ||||||||||
| Title: | MicroRNA-495 suppresses cell proliferation and invasion of hepatocellular carcinoma by directly targeting insulin-like growth factor receptor-1. | ||||||||||
| Author: | Ye, Ying|Zhuang, Juhua|Wang, Guangdong|He, Saifei|Zhang, Suiliang|Wang, Guoyu|Ni, Jing|Wang, Jiening|Xia, Wei | ||||||||||
| PMID: | 29434703 | ||||||||||
| 21. | |||||||||||
| Journal: | Cancer Res. 2018 Jul 15;78(14):3995-4006. | ||||||||||
| Title: | Multikinase Inhibitor CT-707 Targets Liver Cancer by Interrupting the Hypoxia-Activated IGF-1R-YAP Axis. | ||||||||||
| Author: | Zhu, Hong|Wang, Dan-Dan|Yuan, Tao|Yan, Fang-Jie|Zeng, Chen-Ming|Dai, Xiao-Yang|Chen, Zi-Bo|Chen, Ying|Zhou, Tianyi|Fan, Guang-Han|Ying, Meidan|Cao, Ji|Luo, Peihua|Liu, Xi-Jie|Hu, Yuandong|Peng, Yong|He, Qiaojun|Yang, Bo | ||||||||||
| PMID: | 29669759 | ||||||||||
| 22. | |||||||||||
| Journal: | J Cell Biochem. 2018 Aug;119(8):6806-6813. | ||||||||||
| Title: | Higher variety and quantity of microRNA-139-5p isoforms confer suppressive role in hepatocellular carcinoma. | ||||||||||
| Author: | Ni, Hengli|Dai, Xiaoxiao|Leng, Xueqin|Deng, Min|Qin, Yan|Ji, Qinghua|Xu, Chunfang|Li, Jianming|Liu, Yao | ||||||||||
| PMID: | 29693285 | ||||||||||
| 23. | |||||||||||
| Journal: | Int J Mol Sci. 2018 Apr 27;19(5). pii: ijms19051308. | ||||||||||
| Title: | Insulin-Like Growth Factor (IGF) System in Liver Diseases. | ||||||||||
| Author: | Adamek, Agnieszka|Kasprzak, Aldona | ||||||||||
| PMID: | 29702590 | ||||||||||