Primary Site >> Liver Cancer
Gene >> IGF1R
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Ref: The IGF axis and hepatocarcinogenesis. PMID: 11376124 |
Ref: Association of IGF1R polymorphisms with the development of HBV-related hepatocellular carcinoma. PMID: 24758241 Ref: Fatty acid esters of phloridzin induce apoptosis of human liver cancer cells through altered gene expression. PMID: 25229655 |
Ref: Knockdown of SOX18 inhibits the proliferation, migration and invasion of hepatocellular carcinoma cells. PMID: 26151573 Ref: miR-1275: A single microRNA that targets the three IGF2-mRNA-binding proteins hindering tumor growth in hepatocellular carcinoma. PMID: 26160756 |
Ref: Facing the enigma of the vascular network in hepatocellular carcinomas in cirrhotic and non-cirrhotic livers. PMID: 26243063 Ref: The dual targeting of insulin and insulin-like growth factor 1 receptor enhances the mTOR inhibitor-mediated antitumor efficacy in hepatocellular carcinoma. PMID: 26756219 Ref: GRK2 overexpression inhibits IGF1-induced proliferation and migration of human hepatocellular carcinoma cells by downregulating EGR1. PMID: 26936374 Ref: Abrogating the interplay between IGF2BP1, 2 and 3 and IGF1R by let-7i arrests hepatocellular carcinoma growth. PMID: 27126374 Ref: Insulin-like growth factor-binding protein-3 inhibits IGF-1-induced proliferation of human hepatocellular carcinoma cells by controlling bFGF and PDGF autocrine/paracrine loops. PMID: 27521890 Ref: Genomic characterization of liver metastases from colorectal cancer patients. PMID: 27662660 Ref: Bioinformatic identification of IGF1 as a hub gene in hepatocellular carcinoma (HCC) and in-vitro analysis of the chemosensitizing effect of miR-379 via suppressing the IGF1/IGF1R signaling pathway. PMID: 28051262 |
Ref: TGFbeta signaling confers sorafenib resistance via induction of multiple RTKs in hepatocellular carcinoma cells. PMID: 27862334 Ref: Cis-Nerolidol Induces Endoplasmic Reticulum Stress and Cell Death in Human Hepatocellular Carcinoma Cells through Extensive CYP2C19 and CYP1A2 Oxidation. PMID: 28256105 Ref: Co-targeting of IGF1R/mTOR pathway by miR-497 and miR-99a impairs hepatocellular carcinoma development. PMID: 28624790 Ref: MicroRNA-187 inhibits tumor growth and metastasis via targeting of IGF-1R in hepatocellular carcinoma. PMID: 28627639 Ref: The IGF1R/INSR Inhibitor BI 885578 Selectively Inhibits Growth of IGF2-Overexpressing Colorectal Cancer Tumors and Potentiates the Efficacy of Anti-VEGF Therapy. PMID: 28729397 Ref: Therapeutic potential of an anti-angiogenic multimodal biomimetic peptide in hepatocellular carcinoma. PMID: 29254183 |
Ref: Epigenetic alterations contribute to promoter activity of imprinting gene IGF2. PMID: 29413895 Ref: MicroRNA-495 suppresses cell proliferation and invasion of hepatocellular carcinoma by directly targeting insulin-like growth factor receptor-1. PMID: 29434703 Ref: Multikinase Inhibitor CT-707 Targets Liver Cancer by Interrupting the Hypoxia-Activated IGF-1R-YAP Axis. PMID: 29669759 Ref: Higher variety and quantity of microRNA-139-5p isoforms confer suppressive role in hepatocellular carcinoma. PMID: 29693285 Ref: Insulin-Like Growth Factor (IGF) System in Liver Diseases. PMID: 29702590 |