Literatures

Primary Site >> Stomach Cancer

Gene >> IGF1R

1.
Journal:	Cancer Res. 1999 Feb 1;59(3):748-52.
Title:	Comparative genomic hybridization of cancer of the gastroesophageal junction: deletion of 14Q31-32.1 discriminates between esophageal (Barrett's) and gastric cardia adenocarcinomas.
Author:	van Dekken, H\|Geelen, E\|Dinjens, W N\|Wijnhoven, B P\|Tilanus, H W\|Tanke, H J\|Rosenberg, C
PMID:	9973227

2.
Journal:	J Hum Genet. 2001;46(1):21-5.
Title:	IQGAP1, a negative regulator of cell-cell adhesion, is upregulated by gene amplification at 15q26 in gastric cancer cell lines HSC39 and 40A.
Author:	Sugimoto, N\|Imoto, I\|Fukuda, Y\|Kurihara, N\|Kuroda, S\|Tanigami, A\|Kaibuchi, K\|Kamiyama, R\|Inazawa, J
PMID:	11289714

3.
Journal:	J Pathol. 2003 Nov;201(3):430-8.
Title:	Gastric cancer: the role of insulin-like growth factor 2 (IGF 2) and its receptors (IGF 1R and M6-P/IGF 2R).
Author:	Pavelic, Kresimir\|Kolak, Toni\|Kapitanovic, Sanja\|Radosevic, Senka\|Spaventi, Sime\|Kruslin, Bozo\|Pavelic, Jasminka
PMID:	14595755

4.
Journal:	Biochem Biophys Res Commun. 2005 May 13;330(3):760-7.
Title:	Impact of PTEN on the expression of insulin-like growth factors (IGFs) and IGF-binding proteins in human gastric adenocarcinoma cells.
Author:	Yi, Ho-Keun\|Kim, Sun-Young\|Hwang, Pyoung-Han\|Kim, Chan-Young\|Yang, Doo-Hyun\|Oh, Youngman\|Lee, Dae-Yeol
PMID:	15809062

5.
Journal:	J Pediatr Hematol Oncol. 2005 Apr;27(4):179-87.
Title:	Gastrointestinal stromal tumors in children and young adults: a clinicopathologic, molecular, and genomic study of 15 cases and review of the literature.
Author:	Prakash, Sonam\|Sarran, Lisa\|Socci, Nicholas\|DeMatteo, Ronald P\|Eisenstat, Jonathan\|Greco, Alba M\|Maki, Robert G\|Wexler, Leonard H\|LaQuaglia, Michael P\|Besmer, Peter\|Antonescu, Cristina R
PMID:	15838387

6.
Journal:	J Cancer Res Clin Oncol. 2009 Jul;135(7):855-66.
Title:	Gastric cancer in the era of molecularly targeted agents: current drug development strategies.
Author:	Arkenau, Hendrik-Tobias
PMID:	19363621

7.
Journal:	Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2009 Jun;25(6):529-30.
Title:	[Expression and significance of IGF-1R and VEGF in gastric carcinoma].
Author:	Liu, Wei-dong\|Yu, Ren\|Zhou, Guan-rong
PMID:	19500509

8.
Journal:	J Surg Oncol. 2011 Oct;104(5):525-9.
Title:	Expression and prognostic significance of CEACAM6, ITGB1, and CYR61 in peripheral blood of patients with gastric cancer.
Author:	Zhao, Zhong-Sheng\|Li, Li\|Wang, Hui-Ju\|Wang, Yuan-Yu
PMID:	21618249

9.
Journal:	Mol Cancer Ther. 2012 Feb;11(2):439-51.
Title:	Evaluation of the antitumor effects and mechanisms of PF00299804, a pan-HER inhibitor, alone or in combination with chemotherapy or targeted agents in gastric cancer.
Author:	Nam, Hyun-Jin\|Ching, Keith A\|Kan, Julie\|Kim, Hwang-Phill\|Han, Sae-Won\|Im, Seock-Ah\|Kim, Tae-You\|Christensen, James G\|Oh, Do-Youn\|Bang, Yung-Jue
PMID:	22135232

10.
Journal:	Oncogene. 2013 Mar 14;32(11):1363-72.
Title:	MicroRNA-7 functions as an anti-metastatic microRNA in gastric cancer by targeting insulin-like growth factor-1 receptor.
Author:	Zhao, X\|Dou, W\|He, L\|Liang, S\|Tie, J\|Liu, C\|Li, T\|Lu, Y\|Mo, P\|Shi, Y\|Wu, K\|Nie, Y\|Fan, D
PMID:	22614005

11.
Journal:	PLoS One. 2013;8(1):e54644.
Title:	A novel proteomics-based clinical diagnostics technology identifies heterogeneity in activated signaling pathways in gastric cancers.
Author:	Lee, Jeeyun\|Kim, Sung\|Kim, Phillip\|Liu, Xinjun\|Lee, Tani\|Kim, Kyoung-Mee\|Do, In-Gu\|Park, Joon Oh\|Park, Se Hoon\|Jang, Jiryeon\|Hoe, Nicholas\|Harvie, Gulia\|Kuller, Anne\|Jain, Anjali\|Meyer, Gary\|Leesman, Glen\|Park, Young Suk\|Choi, Min Gew\|Sohn, Tae Sung\|Bae,
PMID:	23372746

12.
Journal:	Curr Treat Options Oncol. 2013 Sep;14(3):321-36.
Title:	Met, IGF1R, and other new targets in upper GI malignancies.
Author:	Popa, Elizabeta C\|Shah, Manish A
PMID:	23873272

13.
Journal:	World J Gastroenterol. 2014 Apr 28;20(16):4536-45.
Title:	Targeting receptor tyrosine kinases in gastric cancer.
Author:	Morishita, Asahiro\|Gong, Jian\|Masaki, Tsutomu
PMID:	24782606

14.
Journal:	Cancer Sci. 2014 Dec;105(12):1591-600.
Title:	Immunohistochemical analysis of RTKs expression identified HER3 as a prognostic indicator of gastric cancer.
Author:	Ema, Akira\|Yamashita, Keishi\|Ushiku, Hideki\|Kojo, Ken\|Minatani, Naoko\|Kikuchi, Mariko\|Mieno, Hiroaki\|Moriya, Hiromitsu\|Hosoda, Kei\|Katada, Natsuya\|Kikuchi, Shiro\|Watanabe, Masahiko
PMID:	25455899

15.
Journal:	Med Oncol. 2014 Dec;31(12):141.
Title:	Phosphorylated insulin-like growth factor-1 receptor expression predicts poor prognosis of Chinese patients with gastric cancer.
Author:	Deng, Wen-ying\|Li, Ning\|Wan, Xiang-bin\|Luo, Su-xia\|Zhang, You-wei
PMID:	25348345

16.
Journal:	Pol J Pathol. 2014 Jun;65(2):135-40.
Title:	Expression of insulin-like growth factor receptor type 1 correlate with lymphatic metastases in human gastric cancer.
Author:	Gryko, M\|Kisluk, J\|Cepowicz, D\|Zinczuk, J\|Kamocki, Z\|Guzinska-Ustymowicz, K\|Pryczynicz, A\|Czyzewska, J\|Kemona, A\|Kedra, B
PMID:	25119174

17.
Journal:	Clin Cancer Res. 2014 Sep 1;20(17):4559-73.
Title:	Functional genetic approach identifies MET, HER3, IGF1R, INSR pathways as determinants of lapatinib unresponsiveness in HER2-positive gastric cancer.
Author:	Zhang, Zhe\|Wang, Jiping\|Ji, Dongmei\|Wang, Chenchen\|Liu, Rujiao\|Wu, Zheng\|Liu, Lian\|Zhu, Dan\|Chang, Jinjia\|Geng, Ruixuan\|Xiong, Lei\|Fang, Qiangyi\|Li, Jin
PMID:	24973425

18.
Journal:	Chin Med J (Engl). 2014;127(12):2357-62.
Title:	MiR-503 regulates cisplatin resistance of human gastric cancer cell lines by targeting IGF1R and BCL2.
Author:	Wang, Tongshan\|Ge, Gaoxia\|Ding, Yin\|Zhou, Xin\|Huang, Zebo\|Zhu, Wei\|Shu, Yongqian\|Liu, Ping
PMID:	24931256

19.
Journal:	Anticancer Agents Med Chem. 2014;14(6):884-91.
Title:	miR-1271 regulates cisplatin resistance of human gastric cancer cell lines by targeting IGF1R, IRS1, mTOR, and BCL2.
Author:	Yang, Mifang\|Shan, Xia\|Zhou, Xin\|Qiu, Tianzhu\|Zhu, Wei\|Ding, Yin\|Shu, Yongqian\|Liu, Ping
PMID:	24875127

20.
Journal:	Cell Biosci. 2014 May 5;4:26.
Title:	MicroRNA-206 suppresses gastric cancer cell growth and metastasis.
Author:	Ren, Jun\|Huang, Hui-Jie\|Gong, Yu\|Yue, Shen\|Tang, Li-Ming\|Cheng, Steven Y
PMID:	24855559

21.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2015 Oct;18(10):1051-5.
Title:	[Association of prognosis with insulin-like growth factor receptor type I expression in gastric cancer patients: a meta-analysis].
Author:	Gao, Yunhe\|Cui, Jianxin\|Xi, Hongqing\|Shen, Weisong\|Zhang, Kecheng\|Li, Jiyang\|Liang, Wenquan\|Hu, Chong\|Wei, Bo\|Chen, Lin
PMID:	26499155

22.
Journal:	Sci Rep. 2015 Jun 25;5:11634.
Title:	Development of trastuzumab-resistant human gastric carcinoma cell lines and mechanisms of drug resistance.
Author:	Zuo, Qiang\|Liu, Jing\|Zhang, Jingwen\|Wu, Mengwan\|Guo, Lihong\|Liao, Wangjun
PMID:	26108989

23.
Journal:	World J Gastroenterol. 2015 Mar 14;21(10):2949-58.
Title:	Tumor suppressor role of miR-133a in gastric cancer by repressing IGF1R.
Author:	Gong, Yu\|Ren, Jun\|Liu, Kun\|Tang, Li-Ming
PMID:	25780292

24.
Journal:	Med Oncol. 2015 Jan;32(1):431.
Title:	Insulin-like growth factor pathway aberrations and gastric cancer; evaluation of prognostic significance and assessment of therapeutic potentials.
Author:	Abdel-Rahman, Omar
PMID:	25487446

25.
Journal:	Tumour Biol. 2015 Apr;36(4):2737-45.
Title:	Involvement of miR-143 in cisplatin resistance of gastric cancer cells via targeting IGF1R and BCL2.
Author:	Zhuang, Ming\|Shi, Qin\|Zhang, Xiuwei\|Ding, Yongbin\|Shan, Liuqun\|Shan, Xia\|Qian, Jiaqi\|Zhou, Xin\|Huang, Zebo\|Zhu, Wei\|Ding, Yin\|Cheng, Wenfang\|Liu, Ping\|Shu, Yongqian
PMID:	25492481

26.
Journal:	Oncotarget. 2016 May 24;7(21):31204-14.
Title:	Relationship between insulin-like growth factor axis gene polymorphisms and clinical outcome in advanced gastric cancer patients treated with FOLFOX.
Author:	Oh, Sung Yong\|Shin, Aesun\|Kim, Seong-Geun\|Hwang, Jung-Ah\|Hong, Seung Hyun\|Lee, Yeon-Su\|Kwon, Hyuk-Chan
PMID:	27144430

27.
Journal:	Oncol Rep. 2016 Aug;36(2):1173-9.
Title:	Tanshinone IIA decreases the protein expression of EGFR, and IGFR blocking the PI3K/Akt/mTOR pathway in gastric carcinoma AGS cells both in vitro and in vivo.
Author:	Su, Chin-Cheng\|Chiu, Tsung-Lang
PMID:	27277844

28.
Journal:	Oncotarget. 2016 Aug 23;7(34):54445-54462.
Title:	Importance of the type I insulin-like growth factor receptor in HER2, FGFR2 and MET-unamplified gastric cancer with and without Ras pathway activation.
Author:	Saisana, Marina\|Griffin, S Michael\|May, Felicity E B
PMID:	27437872

29.
Journal:	Am J Transl Res. 2016 Aug 15;8(8):3549-57. eCollection 2016.
Title:	Anti-proliferative role and prognostic implication of miR-141 in gastric cancer.
Author:	Huang, Mingwei\|Wu, Liucheng\|Qin, Yuzhou\|Li, Zhao\|Luo, Shanshan\|Qin, Haiquan\|Yang, Yang\|Chen, Jiansi
PMID:	27648145

30.
Journal:	Eur Rev Med Pharmacol Sci. 2016 Sep;20(18):3818-3824.
Title:	miR-494 inhibits invasion and proliferation of gastric cancer by targeting IGF-1R.
Author:	Zhao, X-Q\|Liang, T-J\|Fu, J-W
PMID:	27735036

31.
Journal:	Eur Rev Med Pharmacol Sci. 2016 Nov;20(21):4409-4410.
Title:	Letter to the Editor - miR-494 inhibits invasion and proliferation of gastric cancer by targeting IGF-1R.
Author:	Cavaliere, C\|D'Aniello, C\|Cerillo, I\|Facchini, G
PMID:	27874961

32.
Journal:	Cell Biol Int. 2017 Jul;41(7):749-760.
Title:	Formation of the IGF1R/CAV1/SRC tri-complex antagonizes TRAIL-induced apoptosis in gastric cancer cells.
Author:	Guo, Tianshu\|Xu, Ling\|Che, Xiaofang\|Zhang, Simeng\|Li, Ce\|Wang, Jin\|Gong, Jing\|Ma, Rui\|Fan, Yibo\|Hou, Kezuo\|Zhou, Huiming\|Hu, Xuejun\|Liu, Yunpeng\|Qu, Xiujuan
PMID:	28403518

33.
Journal:	Zhonghua Zhong Liu Za Zhi. 2017 Dec 23;39(12):916-918.
Title:	[Expression and Prognostic Significance of P-IGF1R in Gastric Cancer].
Author:	Ge, L\|Zhu, J F\|Yu, Z\|Wang, H J
PMID:	29262508

34.
Journal:	Oncotarget. 2017 Aug 7;8(42):72157-72166.
Title:	The crucial role of SRPK1 in IGF-1-induced EMT of human gastric cancer.
Author:	Wang, Hong\|Wang, Chunlei\|Tian, Wenling\|Yao, Yanfen
PMID:	29069776

35.
Journal:	Cell Physiol Biochem. 2017;42(4):1701-1711.
Title:	MicroRNA-302b-3p Suppresses Cell Proliferation Through AKT Pathway by Targeting IGF-1R in Human Gastric Cancer.
Author:	Guo, Bo\|Zhao, Zhenghao\|Wang, Zhen\|Li, Qian\|Wang, Xiaofei\|Wang, Wenjing\|Song, Tusheng\|Huang, Che
PMID:	28743112

36.
Journal:	Mol Med Rep. 2017 Sep;16(3):3664-3672.
Title:	MicroRNA455 is downregulated in gastric cancer and inhibits cell proliferation, migration and invasion via targeting insulinlike growth factor 1 receptor.
Author:	Zhang, Shan\|Yin, Wan-Ling\|Zhang, Xin\|Zhang, Xiao-Yu
PMID:	28714005

37.
Journal:	Cancer Lett. 2017 May 1;393:76-85.
Title:	IGF1/IGF1R/STAT3 signaling-inducible IFITM2 promotes gastric cancer growth and metastasis.
Author:	Xu, Li\|Zhou, Rui\|Yuan, Lezhong\|Wang, Shiqing\|Li, Xiaoyin\|Ma, Huanrong\|Zhou, Minyu\|Pan, Changqie\|Zhang, Jingwen\|Huang, Na\|Shi, Min\|Bin, Jianping\|Liao, Yulin\|Liao, Wangjun
PMID:	28223169

38.
Journal:	Cancer Med. 2017 Jan;6(1):235-244.
Title:	Muscle RAS oncogene homolog (MRAS) recurrent mutation in Borrmann type IV gastric cancer.
Author:	Yasumoto, Makiko\|Sakamoto, Etsuko\|Ogasawara, Sachiko\|Isobe, Taro\|Kizaki, Junya\|Sumi, Akiko\|Kusano, Hironori\|Akiba, Jun\|Torimura, Takuji\|Akagi, Yoshito\|Itadani, Hiraku\|Kobayashi, Tsutomu\|Hasako, Shinichi\|Kumazaki, Masafumi\|Mizuarai, Shinji\|Oie, Shinji\|Yano
PMID:	27891760

39.
Journal:	Gastric Cancer. 2017 Mar;20(2):263-273.
Title:	Impact of insulin-like growth factor-1 receptor and amphiregulin expression on survival in patients with stage II/III gastric cancer enrolled in the Adjuvant Chemotherapy Trial of S-1 for Gastric Cancer.
Author:	Ichikawa, Wataru\|Terashima, Masanori\|Ochiai, Atsushi\|Kitada, Koji\|Kurahashi, Issei\|Sakuramoto, Shinichi\|Katai, Hitoshi\|Sano, Takeshi\|Imamura, Hiroshi\|Sasako, Mitsuru
PMID:	26884344

40.
Journal:	Histopathology. 2018 Mar;72(4):556-568.
Title:	Gastric poorly cohesive carcinoma: a correlative study of mutational signatures and prognostic significance based on histopathological subtypes.
Author:	Kwon, Chae H\|Kim, Young K\|Lee, Sojeong\|Kim, Ahrong\|Park, Hye J\|Choi, Yuri\|Won, Yeo J\|Park, Do Y\|Lauwers, Gregory Y
PMID:	28873240

41.
Journal:	Nat Commun. 2018 May 3;9(1):1777.
Title:	Clinical and genomic landscape of gastric cancer with a mesenchymal phenotype.
Author:	Oh, Sang Cheul\|Sohn, Bo Hwa\|Cheong, Jae-Ho\|Kim, Sang-Bae\|Lee, Jae Eun\|Park, Ki Cheong\|Lee, Sang Ho\|Park, Jong-Lyul\|Park, Yun-Yong\|Lee, Hyun-Sung\|Jang, Hee-Jin\|Park, Eun Sung\|Kim, Sang-Cheol\|Heo, Jeonghoon\|Chu, In-Sun\|Jang, You-Jin\|Mok, Young-Jae\|Jung, Won
PMID:	29725014

42.
Journal:	Oncol Lett. 2018 May;15(5):7000-7006.
Title:	IGF-1-induced MMP-11 expression promotes the proliferation and invasion of gastric cancer cells through the JAK1/STAT3 signaling pathway.
Author:	Su, Chao\|Wang, Wenchang\|Wang, Cunchuan
PMID:	29731870

43.
Journal:	Onco Targets Ther. 2018 May 17;11:2911-2923.
Title:	miR-598 acts as a tumor suppressor in human gastric cancer by targeting IGF-1R.
Author:	Liu, Na\|Yang, Hua\|Wang, Hong
PMID:	29844688

44.
Journal:	Clin Lab. 2018 Oct 1;64(10):1661-1669.
Title:	Identification of Potential Biomarkers Involved in Gastric Cancer Through Integrated Analysis of Non-Coding RNA Associated Competing Endogenous RNAs Network.
Author:	Xing, Chao\|Cai, Zhengzhai\|Gong, Jian\|Zhou, Jun\|Xu, Jingjing\|Guo, Feng
PMID:	30336538

45.
Journal:	Carcinogenesis. 2018 Oct 29. pii: 5146213.
Title:	NUCKS1 promotes gastric cancer cell aggressiveness by upregulating IGF-1R and subsequently activating the PI3K/Akt/mTOR signaling pathway.
Author:	Huang, Ya-Kai\|Kang, Wei-Ming\|Ma, Zhi-Qiang\|Liu, Yu-Qin\|Zhou, Li\|Yu, Jian-Chun
PMID:	30371738