Primary Site >> Esophagus Cancer

Gene >> IGF1

Journal: Cancer Res. 1991 Apr 1;51(7):1898-903.
Title: Overexpression of epidermal growth factor and insulin-like growth factor-I receptors and autocrine stimulation in human esophageal carcinoma cells.
Author: Chen, S C|Chou, C K|Wong, F H|Chang, C M|Hu, C P
PMID: 2004373
Journal: Anticancer Res. 1991 Jul-Aug;11(4):1591-5.
Title: Effects of various growth factors on growth of a cloned human esophageal squamous cancer cell line in a protein-free medium.
Author: Oku, K|Tanaka, A|Yamanishi, H|Nishizawa, Y|Matsumoto, K|Shiozaki, H|Mori, T
PMID: 1746916
Journal: Int J Cancer. 1993 Sep 30;55(3):364-70.
Title: Growth-regulatory mechanism of two human esophageal-cancer cell lines in protein-free conditions.
Author: Iihara, K|Shiozaki, H|Oku, K|Tahara, H|Doki, Y|Oka, H|Kadowaki, T|Iwazawa, T|Inoue, M|Mori, T
PMID: 8375919
Journal: Anesth Analg. 1996 Feb;82(2):258-63.
Title: Postoperative alpha 2-adrenergic stimulation attenuates protein catabolism.
Author: Mertes, N|Goeters, C|Kuhmann, M|Zander, J F
PMID: 8561324
Journal: Cancer Res. 1998 Nov 1;58(21):4802-4.
Title: Sequence alterations of insulin-like growth factor binding protein 3 in neoplastic and normal gastrointestinal tissues.
Author: Zou, T|Fleisher, A S|Kong, D|Yin, J|Souza, R F|Wang, S|Smolinski, K N|Abraham, J M|Meltzer, S J
PMID: 9809981
Journal: J Biomed Sci. 2002 Nov-Dec;9(6 Pt 2):665-74.
Title: Autocrine stimulation by insulin-like growth factor I is involved in the growth, tumorigenicity and chemoresistance of human esophageal carcinoma cells.
Author: Liu, Young-Chau|Leu, Chuen-Miin|Wong, Fen-Hwa|Fong, Wan-Shung|Chen, Shan-Chun|Chang, Chungming|Hu, Cheng-po
PMID: 12432233
Journal: Anticancer Res. 2004 Sep-Oct;24(5A):3029-34.
Title: The role of insulin-like growth factor 1 and insulin-like growth factor binding protein 3 in human esophageal cancer.
Author: Sohda, Makoto|Kato, Hiroyuki|Miyazaki, Tatsuya|Nakajima, Masanobu|Fukuchi, Minoru|Manda, Ryokuhei|Fukai, Yasuyuki|Masuda, Norihiro|Kuwano, Hiroyuki
PMID: 15517912
Journal: Cancer Res. 2004 Nov 1;64(21):7711-23.
Title: Epidermal growth factor receptor regulates aberrant expression of insulin-like growth factor-binding protein 3.
Author: Takaoka, Munenori|Harada, Hideki|Andl, Claudia D|Oyama, Kenji|Naomoto, Yoshio|Dempsey, Kelly L|Klein-Szanto, Andres J|El-Deiry, Wafik S|Grimberg, Adda|Nakagawa, Hiroshi
PMID: 15520175
Journal: Int J Clin Pract. 2006 Dec;60(12):1604-8.
Title: Serum levels of IGF-I and IGFBP-III and their relation with carcinoembryonic antigen and carbohydrate antigen 19-9 in cases of esophageal cancer.
Author: Yilmaz, O|Eroglu, A|Dag, E|Karaoglanoglu, N|Yilmaz, A
PMID: 16704680
Journal: J Thorac Cardiovasc Surg. 2007 Mar;133(3):763-9.
Title: Cytogenetic characterization and gene expression profiling in the rat reflux-induced esophageal tumor model.
Author: Bonde, Pramod|Sui, Guoping|Dhara, Surajit|Wang, Jiaai|Broor, Apoorv|Kim, Irene F|Wiley, John E|Marti, Guy|Duncan, Mark|Jaffee, Elizabeth|Montgomery, Elizabeth|Maitra, Anirban|Harmon, John W
PMID: 17320581
Journal: Cancer Biol Ther. 2007 Apr;6(4):534-40.
Title: IGFBP-3 regulates esophageal tumor growth through IGF-dependent and independent mechanisms.
Author: Takaoka, Munenori|Kim, Seok-Hyun|Okawa, Takaomi|Michaylira, Carmen Z|Stairs, Douglas B|Johnstone, Cameron N|Andl, Claudia D|Rhoades, Ben|Lee, James J|Klein-Szanto, Andres J P|El-Deiry, Wafik S|Nakagawa, Hiroshi
PMID: 17457048
Journal: Cancer Invest. 2010 Aug;28(7):679-88.
Title: Cyclooxygenase-2 inhibitor NS398 enhances radiosensitivity of radioresistant esophageal cancer cells by inhibiting AKT activation and inducing apoptosis.
Author: Che, Shao-Min|Zhang, Xiao-Zhi|Hou, Lei|Song, Tian-Bao
PMID: 20486853
Journal: Apoptosis. 2011 Feb;16(2):174-83.
Title: Insulin-like growth factor 1 mediates 5-fluorouracil chemoresistance in esophageal carcinoma cells through increasing survivin stability.
Author: Juan, Hsien-Chia|Tsai, Hsin-Ting|Chang, Po-Hao|Huang, Chi-Ying F|Hu, Cheng-Po|Wong, Fen-Hwa
PMID: 21082354
Journal: Am J Gastroenterol. 2012 Feb;107(2):196-204.
Title: IGF-1 and its receptor in esophageal cancer: association with adenocarcinoma and visceral obesity.
Author: Doyle, Suzanne L|Donohoe, Claire L|Finn, Stephen P|Howard, Julia M|Lithander, Fiona E|Reynolds, John V|Pidgeon, Graham P|Lysaght, Joanne
PMID: 22146489
Journal: PLoS One. 2014 Mar 7;9(3):e90916.
Title: Polymorphisms in the insulin-like growth factor axis are associated with gastrointestinal cancer.
Author: Ong, Jennie|Salomon, Jody|te Morsche, Rene H M|Roelofs, Hennie M J|Witteman, Ben J M|Dura, Polat|Lacko, Martin|Peters, Wilbert H M
PMID: 24608110
Journal: Genet Mol Res. 2014 Jan 24;13(1):2107-19.
Title: Genetic variations in the IGF-IGFR-IGFBP axis confer susceptibility to lung and esophageal cancer.
Author: Huang, X P|Zhou, W H|Zhang, Y F
PMID: 24615087
Journal: Sci Rep. 2014 Oct 31;4:6855.
Title: Antitumor effects and molecular mechanisms of figitumumab, a humanized monoclonal antibody to IGF-1 receptor, in esophageal carcinoma.
Author: Zhang, Tiehong|Shen, Hongchang|Dong, Wei|Qu, Xiao|Liu, Qi|Du, Jiajun
PMID: 25358597
Journal: Oncotarget. 2015 Sep 22;6(28):25897-916.
Title: IGFBP2 modulates the chemoresistant phenotype in esophageal adenocarcinoma.
Author: Myers, Amy L|Lin, Lin|Nancarrow, Derek J|Wang, Zhuwen|Ferrer-Torres, Daysha|Thomas, Dafydd G|Orringer, Mark B|Lin, Jules|Reddy, Rishindra M|Beer, David G|Chang, Andrew C
PMID: 26317790
Journal: Vaccines (Basel). 2015 Jul 6;3(3):519-43.
Title: Anti-Tumor Effects of Peptide Therapeutic and Peptide Vaccine Antibody Co-targeting HER-1 and HER-2 in Esophageal Cancer (EC) and HER-1 and IGF-1R in Triple-Negative Breast Cancer (TNBC).
Author: Overholser, Jay|Ambegaokar, Kristen Henkins|Eze, Siobhan M|Sanabria-Figueroa, Eduardo|Nahta, Rita|Bekaii-Saab, Tanios|Kaumaya, Pravin T P
PMID: 26350593
Journal: Tumour Biol. 2016 May;37(5):6893-904.
Title: Impact of IGF-1, IGF-1R, and IGFBP-3 promoter methylation on the risk and prognosis of esophageal carcinoma.
Author: Ye, Peng|Qu, Chang-Fa|Hu, Xue-Lin
PMID: 26662570
Journal: Cancer Res Treat. 2017 Jul;49(3):778-789.
Title: Effects and Mechanisms of Metformin on the Proliferation of Esophageal Cancer Cells In Vitro and In Vivo.
Author: Tang, Jian-Cai|An, Rui|Jiang, Yi-Qing|Yang, Jian
PMID: 27857021
Journal: Oncol Rep. 2017 Jun;37(6):3329-3340.
Title: A ligand-based and enediyne-energized bispecific fusion protein targeting epidermal growth factor receptor and insulin-like growth factor-1 receptor shows potent antitumor efficacy against esophageal cancer.
Author: Cao, Hai-Ying|Guo, Xiao-Fang|Zhu, Xiao-Fei|Li, Sai-Sai|Zhen, Yong-Su
PMID: 28498434
Journal: World J Gastroenterol. 2017 May 21;23(19):3488-3495.
Title: Insulin-like growth factor-1, IGF binding protein-3, and the risk of esophageal cancer in a nested case-control study.
Author: Adachi, Yasushi|Nojima, Masanori|Mori, Mitsuru|Yamashita, Kentaro|Yamano, Hiro-O|Nakase, Hiroshi|Endo, Takao|Wakai, Kenji|Sakata, Kiyomi|Tamakoshi, Akiko
PMID: 28596684
Journal: Exp Cell Res. 2018 Jan 15;362(2):362-369.
Title: Simvastatin inhibits the development of radioresistant esophageal cancer cells by increasing the radiosensitivity and reversing EMT process via the PTEN-PI3K/AKT pathway.
Author: Jin, Yingying|Xu, Kun|Chen, Qingjuan|Wang, Baofeng|Pan, Jiyuan|Huang, Shan|Wei, Yang|Ma, Hongbing
PMID: 29208461