Primary Site >> Esophagus Cancer
Gene >> IGF1
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Ref: Effects of various growth factors on growth of a cloned human esophageal squamous cancer cell line in a protein-free medium. PMID: 1746916 Ref: Overexpression of epidermal growth factor and insulin-like growth factor-I receptors and autocrine stimulation in human esophageal carcinoma cells. PMID: 2004373 |
Ref: Growth-regulatory mechanism of two human esophageal-cancer cell lines in protein-free conditions. PMID: 8375919 |
Ref: Postoperative alpha 2-adrenergic stimulation attenuates protein catabolism. PMID: 8561324 |
Ref: Sequence alterations of insulin-like growth factor binding protein 3 in neoplastic and normal gastrointestinal tissues. PMID: 9809981 |
Ref: Autocrine stimulation by insulin-like growth factor I is involved in the growth, tumorigenicity and chemoresistance of human esophageal carcinoma cells. PMID: 12432233 |
Ref: The role of insulin-like growth factor 1 and insulin-like growth factor binding protein 3 in human esophageal cancer. PMID: 15517912 Ref: Epidermal growth factor receptor regulates aberrant expression of insulin-like growth factor-binding protein 3. PMID: 15520175 |
Ref: Serum levels of IGF-I and IGFBP-III and their relation with carcinoembryonic antigen and carbohydrate antigen 19-9 in cases of esophageal cancer. PMID: 16704680 |
Ref: Cytogenetic characterization and gene expression profiling in the rat reflux-induced esophageal tumor model. PMID: 17320581 Ref: IGFBP-3 regulates esophageal tumor growth through IGF-dependent and independent mechanisms. PMID: 17457048 |
Ref: Cyclooxygenase-2 inhibitor NS398 enhances radiosensitivity of radioresistant esophageal cancer cells by inhibiting AKT activation and inducing apoptosis. PMID: 20486853 |
Ref: Insulin-like growth factor 1 mediates 5-fluorouracil chemoresistance in esophageal carcinoma cells through increasing survivin stability. PMID: 21082354 |
Ref: IGF-1 and its receptor in esophageal cancer: association with adenocarcinoma and visceral obesity. PMID: 22146489 |
Ref: Polymorphisms in the insulin-like growth factor axis are associated with gastrointestinal cancer. PMID: 24608110 Ref: Genetic variations in the IGF-IGFR-IGFBP axis confer susceptibility to lung and esophageal cancer. PMID: 24615087 Ref: Antitumor effects and molecular mechanisms of figitumumab, a humanized monoclonal antibody to IGF-1 receptor, in esophageal carcinoma. PMID: 25358597 |
Ref: IGFBP2 modulates the chemoresistant phenotype in esophageal adenocarcinoma. PMID: 26317790 Ref: Anti-Tumor Effects of Peptide Therapeutic and Peptide Vaccine Antibody Co-targeting HER-1 and HER-2 in Esophageal Cancer (EC) and HER-1 and IGF-1R in Triple-Negative Breast Cancer (TNBC). PMID: 26350593 |
Ref: Impact of IGF-1, IGF-1R, and IGFBP-3 promoter methylation on the risk and prognosis of esophageal carcinoma. PMID: 26662570 |
Ref: Effects and Mechanisms of Metformin on the Proliferation of Esophageal Cancer Cells In Vitro and In Vivo. PMID: 27857021 Ref: A ligand-based and enediyne-energized bispecific fusion protein targeting epidermal growth factor receptor and insulin-like growth factor-1 receptor shows potent antitumor efficacy against esophageal cancer. PMID: 28498434 Ref: Insulin-like growth factor-1, IGF binding protein-3, and the risk of esophageal cancer in a nested case-control study. PMID: 28596684 |
Ref: Simvastatin inhibits the development of radioresistant esophageal cancer cells by increasing the radiosensitivity and reversing EMT process via the PTEN-PI3K/AKT pathway. PMID: 29208461 |