Primary Site >> Colorectal Cancer

Gene >> IGF1

1.
Journal: J Clin Endocrinol Metab. 1986 Oct;63(4):879-85.
Title: Insulin receptor proliferation: a mechanism for tumor-associated hypoglycemia.
Author: Stuart, C A|Prince, M J|Peters, E J|Smith, F E|Townsend, C M 3rd|Poffenbarger, P L
PMID: 3528210
2.
Journal: Cancer Res. 1986 Dec;46(12 Pt 1):6169-73.
Title: Enhanced levels of insulin-like growth factor messenger RNA in human colon carcinomas and liposarcomas.
Author: Tricoli, J V|Rall, L B|Karakousis, C P|Herrera, L|Petrelli, N J|Bell, G I|Shows, T B
PMID: 3779638
3.
Journal: Cancer Lett. 1987 Dec;38(1-2):223-30.
Title: Presence of somatomedin receptors on primary human breast and colon carcinomas.
Author: Pollak, M N|Perdue, J F|Margolese, R G|Baer, K|Richard, M
PMID: 2961436
4.
Journal: Int J Cancer. 1987 Nov 15;40(5):646-52.
Title: Simultaneous production of IGF-I and EGF competing growth factors by HT-29 human colon cancer line.
Author: Culouscou, J M|Remacle-Bonnet, M|Garrouste, F|Marvaldi, J|Pommier, G
PMID: 3500134
5.
Journal: Jpn J Cancer Res. 1989 Jan;80(1):51-8.
Title: Insulin and insulin-like growth factor 1 stimulate proliferation of metastatic variants of colon carcinoma 26.
Author: Koenuma, M|Yamori, T|Tsuruo, T
PMID: 2540132
6.
Journal: Mol Endocrinol. 1989 Mar;3(3):509-17.
Title: Analysis of insulin-like growth factor I gene expression in malignancy: evidence for a paracrine role in human breast cancer.
Author: Yee, D|Paik, S|Lebovic, G S|Marcus, R R|Favoni, R E|Cullen, K J|Lippman, M E|Rosen, N
PMID: 2747657
7.
Journal: J Cell Physiol. 1990 Jun;143(3):405-15.
Title: Production of insulin-like growth factor II (IGF-II) and different forms of IGF-binding proteins by HT-29 human colon carcinoma cell line.
Author: Culouscou, J M|Remacle-Bonnet, M|Garrouste, F|Fantini, J|Marvaldi, J|Pommier, G
PMID: 1694180
8.
Journal: Br J Cancer. 1990 Oct;62(4):627-30.
Title: Treatment of patients with metastatic pancreatic and gastrointestinal tumours with the somatostatin analogue Sandostatin: a phase II study including endocrine effects.
Author: Klijn, J G|Hoff, A M|Planting, A S|Verweij, J|Kok, T|Lamberts, S W|Portengen, H|Foekens, J A
PMID: 1977468
9.
Journal: Int J Cancer. 1990 Nov 15;46(5):858-63.
Title: Detection of colonic growth factors using a human colonic carcinoma cell line (LIM1215).
Author: Whithead, R H|Nice, E C|Lloyd, C J|James, R|Burgess, A W
PMID: 2228314
10.
Journal: Adv Cancer Res. 1990;54:213-34.
Title: Growth-regulatory factors for normal, premalignant, and malignant human cells in vitro.
Author: Herlyn, M|Kath, R|Williams, N|Valyi-Nagy, I|Rodeck, U
PMID: 2404378
11.
Journal: Cancer Res. 1991 Jun 1;51(11):2813-9.
Title: Purification of a colon cancer cell growth inhibitor and its identification as an insulin-like growth factor binding protein.
Author: Culouscou, J M|Shoyab, M
PMID: 1709585
12.
Journal: Int J Cancer. 1991 Jul 30;48(6):826-30.
Title: Tumor IGF-II content in a patient with a colon adenocarcinoma correlates with abnormal expression of the gene.
Author: Lambert, S|Collette, J|Gillis, J|Franchimont, P|Desaive, C|Gol-Winkler, R
PMID: 1713573
13.
Journal: Cancer Res. 1991 Nov 1;51(21):5859-65.
Title: Insulin-like growth factor I rapidly induces tyrosine phosphorylation of a Mr 150,000 and a Mr 160,000 protein in highly metastatic mouse colon carcinoma 26 NL-17 cells.
Author: Yamori, T|Iizuka, Y|Takayama, Y|Nishiya, S|Iwashita, S|Yamazaki, A|Takatori, T|Tsuruo, T
PMID: 1718586
14.
Journal: Int J Cancer. 1991 Mar 12;47(5):760-4.
Title: Type-II insulin-like growth-factor receptor in conditioned medium from HT-29 human colon carcinoma cell line.
Author: Garrouste, F|Remacle-Bonnet, M|Culouscou, J M|Marvaldi, J|Pommier, G
PMID: 1848538
15.
Journal: Int J Cancer. 1992 Dec 2;52(6):910-7.
Title: des-(1-3)-IGF-I, an insulin-like growth factor analog used to mimic a potential IGF-II autocrine loop, promotes the differentiation of human colon-carcinoma cells.
Author: Remacle-Bonnet, M|Garrouste, F|el Atiq, F|Roccabianca, M|Marvaldi, J|Pommier, G
PMID: 1281142
16.
Journal: Cancer Lett. 1992 Feb 14;62(1):23-33.
Title: Insulin like growth factor I is an autocrine regulator of human colon cancer cell differentiation and growth.
Author: Baghdiguian, S|Verrier, B|Gerard, C|Fantini, J
PMID: 1311629
17.
Journal: Gastroenterology. 1992 Apr;102(4 Pt 1):1101-8.
Title: Characterization of insulinlike growth factor I receptors in human colon cancer.
Author: Guo, Y S|Narayan, S|Yallampalli, C|Singh, P
PMID: 1312970
18.
Journal: J Clin Endocrinol Metab. 1992 Aug;75(2):609-16.
Title: Expression of type I, but not type II insulin-like growth factor receptor on both undifferentiated and differentiated HT29 human colon carcinoma cell line.
Author: Remacle-Bonnet, M M|Culouscou, J M|Garrouste, F L|Rabenandrasana, C|Marvaldi, J L|Pommier, G J
PMID: 1322432
19.
Journal: Br J Cancer. 1992 Mar;65(3):341-6.
Title: Growth regulation and co-stimulation of human colorectal cancer cell lines by insulin-like growth factor I, II and transforming growth factor alpha.
Author: Lahm, H|Suardet, L|Laurent, P L|Fischer, J R|Ceyhan, A|Givel, J C|Odartchenko, N
PMID: 1558785
20.
Journal: Int J Cancer. 1993 Feb 1;53(3):426-31.
Title: Monocyte-conditioned media possess a novel factor which increases motility of cancer cells.
Author: Jiang, W G|Puntis, M C|Hallett, M B
PMID: 8428796
21.
Journal: Int J Cancer. 1994 May 15;57(4):491-7.
Title: Alterations in serum levels of insulin-like growth factors and insulin-like growth-factor-binding proteins in patients with colorectal cancer.
Author: el Atiq, F|Garrouste, F|Remacle-Bonnet, M|Sastre, B|Pommier, G
PMID: 7514152
22.
Journal: Am J Physiol. 1994 Oct;267(4 Pt 1):G608-17.
Title: Expression of IGF-II and IGF-binding proteins by colon cancer cells in relation to growth response to IGFs.
Author: Singh, P|Dai, B|Yallampalli, C|Xu, Z
PMID: 7524348
23.
Journal: Cancer Res. 1994 Dec 15;54(24):6563-70.
Title: Episomal expression of sense and antisense insulin-like growth factor (IGF)-binding protein-4 complementary DNA alters the mitogenic response of a human colon cancer cell line (HT-29) by mechanisms that are independent of and dependent upon IGF-I.
Author: Singh, P|Dai, B|Dhruva, B|Widen, S G
PMID: 7527300
24.
Journal: J Recept Res. 1994 Jul;14(5):319-33.
Title: Surface distribution of the EGF receptor during differentiation of the human colon carcinoma cell line HT29-D4.
Author: Lehmann, M|Remacle-Bonnet, M|Garrouste, F|Luis, J|Rabenandrasana, C|Marvaldi, J|Pommier, G
PMID: 7815389
25.
Journal: Int J Cancer. 1994 Aug 1;58(3):452-9.
Title: Blockade of the insulin-like growth-factor-I receptor inhibits growth of human colorectal cancer cells: evidence of a functional IGF-II-mediated autocrine loop.
Author: Lahm, H|Amstad, P|Wyniger, J|Yilmaz, A|Fischer, J R|Schreyer, M|Givel, J C
PMID: 8050827
26.
Journal: Mol Cell Endocrinol. 1994 May;101(1-2):141-50.
Title: Human colon carcinoma cells (CaCo-2) synthesize IGF-II and express IGF-I receptors and IGF-II/M6P receptors.
Author: Hoeflich, A|Yang, Y|Kessler, U|Heinz-Erian, P|Kolb, H|Kiess, W
PMID: 9397946
27.
Journal: Exp Cell Res. 1995 Feb;216(2):342-51.
Title: Constitutive or inducible overexpression of the IGF-2 gene in cells of a human colon carcinoma cell line.
Author: Lamonerie, T|Lavialle, C|de Galle, B|Binoux, M|Brison, O
PMID: 7531153
28.
Journal: Eur J Cancer. 1995;31A(1):50-5.
Title: Type I insulin-like growth factor receptors in human colorectal cancer.
Author: Adenis, A|Peyrat, J P|Hecquet, B|Delobelle, A|Depadt, G|Quandalle, P|Bonneterre, J|Demaille, A
PMID: 7695979
29.
Journal: J Clin Invest. 1995 Apr;95(4):1897-905.
Title: Apoptosis induced by an anti-epidermal growth factor receptor monoclonal antibody in a human colorectal carcinoma cell line and its delay by insulin.
Author: Wu, X|Fan, Z|Masui, H|Rosen, N|Mendelsohn, J
PMID: 7706497
30.
Journal: Int J Cancer. 1995 May 16;61(4):587-92.
Title: IGF-2 autocrine stimulation in tumorigenic clones of a human colon-carcinoma cell line.
Author: Lamonerie, T|Lavialle, C|Haddada, H|Brison, O
PMID: 7759165
31.
Journal: Dig Dis Sci. 1995 Mar;40(3):485-94.
Title: Expression of growth factor receptor-encoded mRNA by colonic epithelial cells is altered in inflammatory bowel disease.
Author: Alexander, R J|Panja, A|Kaplan-Liss, E|Mayer, L|Raicht, R F
PMID: 7895532
32.
Journal: Br J Cancer. 1995 Dec;72(6):1447-53.
Title: Activation of the E-cadherin/catenin complex in human MCF-7 breast cancer cells by all-trans-retinoic acid.
Author: Vermeulen, S J|Bruyneel, E A|van Roy, F M|Mareel, M M|Bracke, M E
PMID: 8519658
33.
Journal: Cancer Lett. 1996 May 15;103(1):71-7.
Title: The lack of an effect by insulin or insulin-like growth factor-1 in attenuating colon-2-mediated cancer cachexia.
Author: Lazarus, D D|Kambayashi, T|Lowry, S f|Strassmann, G
PMID: 8616811
34.
Journal: Biochem J. 1996 May 1;315 ( Pt 3):767-74.
Title: Growth inhibition signalled through the interleukin-4/interleukin-13 receptor complex is associated with tyrosine phosphorylation of insulin receptor substrate-1.
Author: Schnyder, B|Lahm, H|Woerly, G|Odartchenko, N|Ryffel, B|Car, B D
PMID: 8645156
35.
Journal: Cancer. 1996 Jul 1;78(1):35-42.
Title: A dose-finding study of lanreotide (a somatostatin analog) in patients with colorectal carcinoma.
Author: Di Leo, A|Bajetta, E|Ferrari, L|Biganzoli, L|Mariani, L|Carnaghi, C|Camerini, E|Buzzoni, R|Ruiz, J M
PMID: 8646723
36.
Journal: J Biol Chem. 1996 Jul 19;271(29):17453-62.
Title: Mevalonic acid is limiting for N-linked glycosylation and translocation of the insulin-like growth factor-1 receptor to the cell surface. Evidence for a new link between 3-hydroxy-3-methylglutaryl-coenzyme a reductase and cell growth.
Author: Carlberg, M|Dricu, A|Blegen, H|Wang, M|Hjertman, M|Zickert, P|Hoog, A|Larsson, O
PMID: 8663239
37.
Journal: Anticancer Res. 1996 Mar-Apr;16(2):861-5.
Title: Cytokine regulation of ezrin expression in the human colon cancer cell line HT29.
Author: Jiang, W G|Hiscox, S
PMID: 8687142
38.
Journal: Digestion. 1996;57 Suppl 1:72-6.
Title: The role of somatostatin analogues in the treatment of gastro-enteropancreatic endocrine tumours.
Author: Bajetta, E|Carnaghi, C|Ferrari, L|Spagnoli, I|Mazzaferro, V|Buzzoni, R
PMID: 8813475
39.
Journal: J Biol Chem. 1996 Nov 15;271(46):29483-8.
Title: Induction of vascular endothelial growth factor by insulin-like growth factor 1 in colorectal carcinoma.
Author: Warren, R S|Yuan, H|Matli, M R|Ferrara, N|Donner, D B
PMID: 8910616
40.
Journal: Braz J Med Biol Res. 1996 Dec;29(12):1593-7.
Title: Insulin receptor tyrosine kinase activity in colon carcinoma.
Author: Corleta, H E|Capp, E|Corleta, O C
PMID: 9222417
41.
Journal: Br J Cancer. 1997;76(1):60-6.
Title: Insulin-like growth factors and their binding proteins in human colonocytes: preferential degradation of insulin-like growth factor binding protein 2 in colonic cancers.
Author: Michell, N P|Langman, M J|Eggo, M C
PMID: 9218734
42.
Journal: J Gastroenterol. 1997 Aug;32(4):528-32.
Title: A rare case of gastric cancer in an acromegalic patient.
Author: Asai, K|Shimoyama, S|Sanno, N|Kaminishi, M|Oohara, T
PMID: 9250902
43.
Journal: Gastroenterology. 1997 Sep;113(3):767-72.
Title: Inhibition of tumor cell kinetics and serum insulin growth factor I levels by octreotide in colorectal cancer patients.
Author: Cascinu, S|Del Ferro, E|Grianti, C|Ligi, M|Ghiselli, R|Foglietti, G|Saba, V|Lungarotti, F|Catalano, G
PMID: 9287967
44.
Journal: Clin Endocrinol (Oxf). 1997 Jul;47(1):17-22.
Title: Acromegaly, colonic polyps and carcinoma.
Author: Jenkins, P J|Fairclough, P D|Richards, T|Lowe, D G|Monson, J|Grossman, A|Wass, J A|Besser, M
PMID: 9302367
45.
Journal: Int J Cancer. 1997 Sep 4;72(5):835-43.
Title: Surface-bound plasmin induces selective proteolysis of insulin-like-growth-factor (IGF)-binding protein-4 (IGFBP-4) and promotes autocrine IGF-II bio-availability in human colon-carcinoma cells.
Author: Remacle-Bonnet, M M|Garrouste, F L|Pommier, G J
PMID: 9311602
46.
Journal: Growth Factors. 1997;14(4):269-77.
Title: Insulin-like growth factor binding proteins as mediators of IGF-I effects on colon cancer cell proliferation.
Author: Michell, N P|Dent, S|Langman, M J|Eggo, M C
PMID: 9386991
47.
Journal: Int J Cancer. 1997 Dec 10;73(6):885-90.
Title: Paracrine interactions between mesothelial and colon-carcinoma cells in a rat model.
Author: van der Wal, B C|Hofland, L J|Marquet, R L|van Koetsveld, P M|van Rossen, M E|van Eijck, C H
PMID: 9399671
48.
Journal: Cancer Epidemiol Biomarkers Prev. 1997 Dec;6(12):1007-10.
Title: Diabetes mellitus and colorectal cancer risk.
Author: La Vecchia, C|Negri, E|Decarli, A|Franceschi, S
PMID: 9419395
49.
Journal: J Nutr. 1998 Feb;128(2):158-65.
Title: Insulin-like growth factor-I and II receptor expression in rat colon mucosa are affected by dietary lipid intake.
Author: Zhang, W|Thornton, W H|MacDonald, R S
PMID: 9446837
50.
Journal: J Cell Physiol. 1998 May;175(2):141-8.
Title: Insulin-like growth factor-I promotes multidrug resistance in MCLM colon cancer cells.
Author: Guo, Y S|Jin, G F|Houston, C W|Thompson, J C|Townsend, C M Jr
PMID: 9525472
51.
Journal: Cancer Res. 1998 Sep 1;58(17):4008-14.
Title: Regulation of vascular endothelial growth factor expression in human colon cancer by insulin-like growth factor-I.
Author: Akagi, Y|Liu, W|Zebrowski, B|Xie, K|Ellis, L M
PMID: 9731515
52.
Journal: J Cell Sci. 1998 Oct;111 ( Pt 20):3119-27.
Title: Integrin ligation and PKC activation are required for migration of colon carcinoma cells.
Author: Rigot, V|Lehmann, M|Andre, F|Daemi, N|Marvaldi, J|Luis, J
PMID: 9739085
53.
Journal: FEBS Lett. 1998 Sep 4;434(3):329-34.
Title: Insulin-like growth factor-binding protein-2 inhibits proliferation of human embryonic kidney fibroblasts and of IGF-responsive colon carcinoma cell lines.
Author: Hoflich, A|Lahm, H|Blum, W|Kolb, H|Wolf, E
PMID: 9742949
54.
Journal: Cancer Res. 1998 Nov 1;58(21):4802-4.
Title: Sequence alterations of insulin-like growth factor binding protein 3 in neoplastic and normal gastrointestinal tissues.
Author: Zou, T|Fleisher, A S|Kong, D|Yin, J|Souza, R F|Wang, S|Smolinski, K N|Abraham, J M|Meltzer, S J
PMID: 9809981
55.
Journal: Growth Horm IGF Res. 1998 Dec;8(6):473-9.
Title: Role of insulin-like growth factor-I (IGF-I) receptor, IGF-I, and IGF binding protein-2 in human colorectal cancers.
Author: Mishra, L|Bass, B|Ooi, B S|Sidawy, A|Korman, L
PMID: 10985759
56.
Journal: J Natl Cancer Inst. 1999 Apr 7;91(7):620-5.
Title: Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3.
Author: Ma, J|Pollak, M N|Giovannucci, E|Chan, J M|Tao, Y|Hennekens, C H|Stampfer, M J
PMID: 10203281
57.
Journal: J Cancer Res Clin Oncol. 1999 Jul;125(7):379-88.
Title: Inhibition of epidermal-growth-factor-receptor-dependent signalling by tyrphostins A25 and AG1478 blocks growth and induces apoptosis in colorectal tumor cells in vitro.
Author: Partik, G|Hochegger, K|Schorkhuber, M|Marian, B
PMID: 10394957
58.
Journal: Int J Cancer. 1999 Sep 24;83(1):15-7.
Title: IGF-I and IGF-II in relation to colorectal cancer.
Author: Manousos, O|Souglakos, J|Bosetti, C|Tzonou, A|Chatzidakis, V|Trichopoulos, D|Adami, H O|Mantzoros, C
PMID: 10449601
59.
Journal: Hum Pathol. 1999 Oct;30(10):1128-33.
Title: Expression of insulin-like growth factor-1 receptor in human colorectal cancer.
Author: Hakam, A|Yeatman, T J|Lu, L|Mora, L|Marcet, G|Nicosia, S V|Karl, R C|Coppola, D
PMID: 10534157
60.
Journal: Trends Endocrinol Metab. 1999 Dec;10(10):383-391.
Title: Antagonistic Analogs of Growth Hormone-releasing Hormone: New Potential Antitumor Agents.
Author: Schally|Varga
PMID: 10542394
61.
Journal: J Natl Cancer Inst. 1999 Dec 1;91(23):2051-2.
Title: Re: Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3.
Author: Renehan, A G|O'Dwyer, S T|Shalet, S M
PMID: 10580038
62.
Journal: Horm Res. 1999;51 Suppl 3:34-41.
Title: Insulin-like growth factor-I and binding protein-3 and risk of cancer.
Author: Giovannucci, E
PMID: 10592442
63.
Journal: Horm Res. 1999;51 Suppl 3:42-51.
Title: IGFs and human cancer: implications regarding the risk of growth hormone therapy.
Author: Shim, M|Cohen, P
PMID: 10592443
64.
Journal: Horm Res. 1999;51 Suppl 3:141-8.
Title: Determination of insulin-like growth factor-I in the monitoring of growth hormone treatment with respect to efficacy of treatment and side effects: should potential risks of cardiovascular disease and cancer be considered?
Author: Juul, A
PMID: 10592459
65.
Journal: Med Hypotheses. 1999 Dec;53(6):459-85.
Title: Vegan proteins may reduce risk of cancer, obesity, and cardiovascular disease by promoting increased glucagon activity.
Author: McCarty, M F
PMID: 10687887
66.
Journal: Adv Exp Med Biol. 1999;472:29-42.
Title: Nutritional factors in human cancers.
Author: Giovannucci, E
PMID: 10736613
67.
Journal: J Cell Physiol. 2000 Apr;183(1):1-9.
Title: Role of insulin-like growth factors and their binding proteins in growth control and carcinogenesis.
Author: Grimberg, A|Cohen, P
PMID: 10699960
68.
Journal: J Cell Biochem Suppl. 2000;34:84-96.
Title: Chemoprevention of breast cancer: the Italian experience.
Author: Decensi, A|Bonanni, B|Guerrieri-Gonzaga, A|Torrisi, R|Manetti, L|Robertson, C|De Palo, G|Formelli, F|Costa, A|Veronesi, U
PMID: 10762020
69.
Journal: Clin Endocrinol (Oxf). 2000 Apr;52(4):457-62.
Title: One year growth hormone replacement therapy does not alter colonic epithelial cell proliferation in growth hormone deficient adults.
Author: Beentjes, J A|van Gorkom, B A|Sluiter, W J|de Vries, E G|Kleibeuker, J H|Dullaart, R P
PMID: 10762288
70.
Journal: Cancer Res. 2000 Apr 1;60(7):2007-17.
Title: Insulin-like growth factor-I protects colon cancer cells from death factor-induced apoptosis by potentiating tumor necrosis factor alpha-induced mitogen-activated protein kinase and nuclear factor kappaB signaling pathways.
Author: Remacle-Bonnet, M M|Garrouste, F L|Heller, S|Andre, F|Marvaldi, J L|Pommier, G J
PMID: 10766192
71.
Journal: Cancer Gene Ther. 2000 Mar;7(3):456-65.
Title: Enhancement of immunogenicity of tumor cells by cotransfection with genes encoding antisense insulin-like growth factor-1 and B7.1 molecules.
Author: Liu, Y|Wang, H|Zhao, J|Ma, J|Wei, L|Wu, S|Xie, T|Shen, F|Trojan, J|Habib, N|Anthony, D D|Wu, M|Guo, Y
PMID: 10766352
72.
Journal: Cancer Epidemiol Biomarkers Prev. 2000 Apr;9(4):345-9.
Title: A prospective study of plasma insulin-like growth factor-1 and binding protein-3 and risk of colorectal neoplasia in women.
Author: Giovannucci, E|Pollak, M N|Platz, E A|Willett, W C|Stampfer, M J|Majeed, N|Colditz, G A|Speizer, F E|Hankinson, S E
PMID: 10794477
73.
Journal: Br J Cancer. 2000 May;82(10):1724-31.
Title: Antagonists of growth hormone-releasing hormone (GH-RH) inhibit IGF-II production and growth of HT-29 human colon cancers.
Author: Szepeshazi, K|Schally, A V|Groot, K|Armatis, P|Halmos, G|Herbert, F|Szende, B|Varga, J L|Zarandi, M
PMID: 10817510
74.
Journal: Endocr J. 2000 Mar;47 Suppl:S57-60.
Title: Incidence of malignant tumors in patients with acromegaly.
Author: Higuchi, Y|Saeki, N|Iuchi, T|Uchino, Y|Tatsuno, I|Uchida, D|Tanaka, T|Noguchi, Y|Nakamura, S|Yasuda, T|Yamaura, A|Sunami, K|Oka, Y|Uozumi, A
PMID: 10890185
75.
Journal: Cancer Res. 2000 Jul 1;60(13):3631-7.
Title: Mirk protein kinase is a mitogen-activated protein kinase substrate that mediates survival of colon cancer cells.
Author: Lee, K|Deng, X|Friedman, E
PMID: 10910078
76.
Journal: Growth Horm IGF Res. 2000 Apr;10 Suppl A:S28-9.
Title: A prospective study of plasma levels of insulin-like growth factor I (IGF-I) and IGF-binding protein-3, and colorectal cancer risk among men.
Author: Ma, J|Pollak, M|Giovannucci, E|Chan, J M|Tao, Y|Hennekens, C|Stampfer, M J
PMID: 10984282
77.
Journal: J Clin Endocrinol Metab. 2000 Sep;85(9):3402-8.
Title: Circulating insulin-like growth factor II and colorectal adenomas.
Author: Renehan, A G|Painter, J E|O'Halloran, D|Atkin, W S|Potten, C S|O'Dwyer, S T|Shalet, S M
PMID: 10999841
78.
Journal: J Clin Endocrinol Metab. 2000 Sep;85(9):3417-24.
Title: The prevalence and characteristics of colorectal neoplasia in acromegaly.
Author: Renehan, A G|Bhaskar, P|Painter, J E|O'Dwyer, S T|Haboubi, N|Varma, J|Ball, S G|Shalet, S M
PMID: 10999843
79.
Journal: J Natl Cancer Inst. 2000 Oct 4;92(19):1592-600.
Title: Serum C-peptide, insulin-like growth factor (IGF)-I, IGF-binding proteins, and colorectal cancer risk in women.
Author: Kaaks, R|Toniolo, P|Akhmedkhanov, A|Lukanova, A|Biessy, C|Dechaud, H|Rinaldi, S|Zeleniuch-Jacquotte, A|Shore, R E|Riboli, E
PMID: 11018095
80.
Journal: Proc Natl Acad Sci U S A. 2000 Oct 24;97(22):12103-8.
Title: Insulin-like growth factor 1 regulates the location, stability, and transcriptional activity of beta-catenin.
Author: Playford, M P|Bicknell, D|Bodmer, W F|Macaulay, V M
PMID: 11035789
81.
Journal: J Surg Res. 2000 Nov;94(1):1-5.
Title: Insulin-like growth factor I receptor antagonism augments response to chemoradiation therapy in colon cancer cells.
Author: Perer, E S|Madan, A K|Shurin, A|Zakris, E|Romeguera, K|Pang, Y|Beech, D J
PMID: 11038295
82.
Journal: Br J Cancer. 2000 Nov;83(10):1344-50.
Title: Elevated serum insulin-like growth factor (IGF)-II and IGF binding protein-2 in patients with colorectal cancer.
Author: Renehan, A G|Jones, J|Potten, C S|Shalet, S M|O'Dwyer, S T
PMID: 11044360
83.
Journal: J Natl Cancer Inst. 2000 Dec 6;92(23):1947-50.
Title: More about: prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3.
Author: Paterson, A C|Leeding, K S|Bach, L A|Baldwin, G S|Macrae, F A|Shulkes, A
PMID: 11106691
84.
Journal: J Natl Cancer Inst. 2000 Dec 6;92(23):1949.
Title: RESPONSE: more about: prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3
Author: Renehan|O'Dwyer|Shalet
PMID: 11106693
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Title: RESPONSE: more about: prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF- binding protein-3
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Journal: Oncogene. 2000 Nov 16;19(48):5517-24.
Title: IGF-II/IGF-I receptor pathway up-regulates COX-2 mRNA expression and PGE2 synthesis in Caco-2 human colon carcinoma cells.
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Title: Does the GH-IGF axis play a role in cancer pathogenesis?
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Title: High-risk colorectal adenomas and serum insulin-like growth factors.
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Title: Incidence of a second tumor in hypopituitary patients operated for pituitary tumors.
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Title: Effect of inflammatory cytokines and growth factors on tumour cell adhesion to the peritoneum.
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Title: Insulin-like growth factor (IGF)-binding protein-6 inhibits IGF-II-induced but not basal proliferation and adhesion of LIM 1215 colon cancer cells.
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Title: Energy balance and cancer: the role of insulin and insulin-like growth factor-I.
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Title: Fibroblast growth factor and insulin-like growth factor differentially modulate the apoptosis and G1 arrest induced by anti-epidermal growth factor receptor monoclonal antibody.
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Title: Increased levels of insulin-like growth factor binding protein-2 in sera and tumours from patients with colonic neoplasia with and without acromegaly.
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Title: Inhibition of proprotein convertases is associated with loss of growth and tumorigenicity of HT-29 human colon carcinoma cells: importance of insulin-like growth factor-1 (IGF-1) receptor processing in IGF-1-mediated functions.
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Title: Androgenic progestins amplify the breast cancer risk associated with hormone replacement therapy by boosting IGF-I activity.
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Title: The interaction of insulin-like growth factor-I with the N-terminal domain of IGFBP-5.
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Title: Milk intake, circulating levels of insulin-like growth factor-I, and risk of colorectal cancer in men.
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Title: The growth hormone-insulin-like growth factor-I axis and colorectal cancer.
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Title: Clinical features and therapeutic outcomes of 65 patients with acromegaly at Tokyo Women's Medical University.
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Title: IGF-1, IGF-2 and IGFBP-3 in prediagnostic serum: association with colorectal cancer in a cohort of Chinese men in Shanghai.
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Title: Nutrition and health: epidemiology of diet, cancer and cardiovascular disease in Italy.
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Title: Circulating insulin-like growth factor-I levels regulate colon cancer growth and metastasis.
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Journal: J Natl Cancer Inst. 2002 Mar 20;94(6):454-60.
Title: Association of a common polymorphism in the human GH1 gene with colorectal neoplasia.
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Title: Insulin-like growth factor-I has a biphasic effect on colon carcinoma cells through transient inactivation of forkhead1, initially mitogenic, then mediating growth arrest and differentiation.
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Journal: Gut. 2002 May;50(5):642-6.
Title: Plasma insulin-like growth factor 1, insulin-like growth factor binding protein 3, and risk of colorectal cancer: a prospective study in northern Sweden.
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Journal: Oncogene. 2002 Apr 25;21(18):2785-96.
Title: Activation of the TGFalpha autocrine loop is downstream of IGF-I receptor activation during mitogenesis in growth factor dependent human colon carcinoma cells.
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Title: Prevention of cytokine-induced apoptosis by insulin-like growth factor-I is independent of cell adhesion molecules in HT29-D4 colon carcinoma cells-evidence for a NF-kappaB-dependent survival mechanism.
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Journal: J Gastroenterol Hepatol. 2002 May;17(5):563-70.
Title: Decreased production of insulin-like growth factor-binding protein (IGFBP)-6 by transfection of colon cancer cells with an antisense IGFBP-6 cDNA construct leads to stimulation of cell proliferation.
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Journal: Ann N Y Acad Sci. 2002 Jun;963:268-81.
Title: Effects of weight control and physical activity in cancer prevention: role of endogenous hormone metabolism.
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Journal: J Natl Cancer Inst. 2002 Jul 3;94(13):972-80.
Title: Insulin, insulin-like growth factor-I (IGF-I), IGF binding proteins, their biologic interactions, and colorectal cancer.
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Journal: J Biol Chem. 2002 Sep 27;277(39):36602-10. Epub 2002 Jul 24.
Title: Regulation of TRAIL expression by the phosphatidylinositol 3-kinase/Akt/GSK-3 pathway in human colon cancer cells.
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Journal: Lancet. 2002 Jul 27;360(9329):273-7.
Title: Risk of cancer in patients treated with human pituitary growth hormone in the UK, 1959-85: a cohort study.
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Journal: J Biol Chem. 2002 Oct 11;277(41):38205-11.
Title: Insulin-like growth factor 1 induces hypoxia-inducible factor 1-mediated vascular endothelial growth factor expression, which is dependent on MAP kinase and phosphatidylinositol 3-kinase signaling in colon cancer cells.
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Journal: J Biol Chem. 2002 Oct 25;277(43):40549-56. Epub 2002 Aug 19.
Title: Opposing effects of 15-lipoxygenase-1 and -2 metabolites on MAPK signaling in prostate. Alteration in peroxisome proliferator-activated receptor gamma.
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Journal: Tumour Biol. 2002 May-Jun;23(3):130-8.
Title: Local expression of insulin-like growth factor-I affects angiogenesis in colorectal cancer.
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Journal: Cancer Epidemiol Biomarkers Prev. 2002 Sep;11(9):901-5.
Title: Insulin-like growth factor II and colorectal cancer risk in women.
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Journal: Gastroenterology. 2002 Oct;123(4):1191-204.
Title: Effects of genetic blockade of the insulin-like growth factor receptor in human colon cancer cell lines.
Author: Adachi, Yasushi|Lee, Choon-Taek|Coffee, Keith|Yamagata, Noboru|Ohm, Joyce E|Park, Kyung-Ho|Dikov, Mikhail M|Nadaf, Sorena R|Arteaga, Carlos L|Carbone, David P
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Journal: Clin Cancer Res. 2002 Oct;8(10):3259-69.
Title: Blockade of insulin-like growth factor I receptor function inhibits growth and angiogenesis of colon cancer.
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Journal: Lab Invest. 2002 Oct;82(10):1377-89.
Title: Impact of insulin-like growth factor receptor-I function on angiogenesis, growth, and metastasis of colon cancer.
Author: Reinmuth, Niels|Fan, Fan|Liu, Wenbiao|Parikh, Alexander A|Stoeltzing, Oliver|Jung, Young D|Bucana, Corazon D|Radinsky, Robert|Gallick, Gary E|Ellis, Lee M
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Journal: Cancer. 2002 Nov 15;95(10):2086-95.
Title: Overexpression of the insulin-like growth factor I receptor in human colon carcinomas.
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Journal: Free Radic Biol Med. 2002 Dec 1;33(11):1499-506.
Title: Extracellular thiol/disulfide redox state affects proliferation rate in a human colon carcinoma (Caco2) cell line.
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Journal: IARC Sci Publ. 2002;156:289-93.
Title: Nutrition, energy balance and colon cancer risk: the role of insulin and insulin-like growth factor-I.
Author: Kaaks, R
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Journal: Ann N Y Acad Sci. 2002 Nov;973:555-8.
Title: Type I insulin-like growth factor receptor expression on colorectal adenocarcinoma cell lines is decreased in response to the chemopreventive agent N-acetyl-l-cysteine.
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Journal: Gastroenterol Clin North Am. 2002 Dec;31(4):925-43.
Title: Modifiable risk factors for colon cancer.
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Journal: Cancer Epidemiol Biomarkers Prev. 2002 Dec;11(12):1597-604.
Title: Effects of a 9-month strength training intervention on insulin, insulin-like growth factor (IGF)-I, IGF-binding protein (IGFBP)-1, and IGFBP-3 in 30-50-year-old women.
Author: Schmitz, Kathryn H|Ahmed, Rehana L|Yee, Douglas
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Journal: J Recept Signal Transduct Res. 2002 Feb-Nov;22(1-4):213-28.
Title: Mono- or dual-phosphorylation of akt kinase is regulated by distinct receptors that involve the common insulin receptor substrate.
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Journal: Pituitary. 2002 Jan;5(1):21-5.
Title: Oncological complications of excess GH in acromegaly.
Author: Webb, Susan M|Casanueva, Felipe|Wass, John A H
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Journal: J Antibiot (Tokyo). 2003 Jan;56(1):1-5.
Title: Byssochlamysol, a new antitumor steroid against IGF-1-dependent cells from Byssochlamys nivea. I. Taxonomy, fermentation, isolation and biological activity.
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Journal: Exp Biol Med (Maywood). 2003 Apr;228(4):396-405.
Title: Insulin resistance and its contribution to colon carcinogenesis.
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Journal: Cancer Causes Control. 2003 Feb;14(1):75-84.
Title: Body mass index and colon cancer: an evaluation of the modifying effects of estrogen (United States).
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Journal: J Endocrinol Invest. 2003 Feb;26(2):163-9.
Title: Acromegaly due to ectopic secretion of GHRH by bronchial carcinoid in a patient with empty sella.
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Journal: J Natl Cancer Inst. 2003 Jun 18;95(12):914-6.
Title: Glycemic load, carbohydrate intake, and risk of colorectal cancer in women: a prospective cohort study.
Author: Terry, Paul D|Jain, Meera|Miller, Anthony B|Howe, Geoffrey R|Rohan, Thomas E
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Journal: Anticancer Res. 2003 Mar-Apr;23(2B):1517-24.
Title: Insulin-like growth factor 1 receptor activates c-SRC and modifies transformation and motility of colon cancer in vitro.
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Journal: Virchows Arch. 2003 Aug;443(2):139-45. Epub 2003 Jul 5.
Title: IGF-1R, IGF-1 and IGF-2 expression as potential prognostic and predictive markers in colorectal-cancer.
Author: Peters, Gerrit|Gongoll, Silvia|Langner, Cord|Mengel, Michael|Piso, Pompiliu|Klempnauer, Jurgen|Ruschoff, Josef|Kreipe, Hans|von Wasielewski, Reinhard
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Journal: J Nutr. 2003 Aug;133(8):2675-81.
Title: Conjugated linoleic acid downregulates insulin-like growth factor-I receptor levels in HT-29 human colon cancer cells.
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Journal: Am J Epidemiol. 2003 Sep 1;158(5):424-31.
Title: Serum insulin-like growth factor I and subsequent risk of colorectal cancer among Japanese-American men.
Author: Nomura, Abraham M Y|Stemmermann, Grant N|Lee, James|Pollak, Michael N
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Journal: Med Hypotheses. 2003 Nov-Dec;61(5-6):567-73.
Title: Hyperinsulinemia may boost both hematocrit and iron absorption by up-regulating activity of hypoxia-inducible factor-1alpha.
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Journal: Cancer Res. 2003 Nov 15;63(22):7708-16.
Title: Insulin-like growth factor 1 receptor enhances invasion and induces resistance to apoptosis of colon cancer cells through the Akt/Bcl-x(L) pathway.
Author: Sekharam, Madhavi|Zhao, Haiyan|Sun, Mei|Fang, Quan|Zhang, Qingbo|Yuan, Zengqiang|Dan, Han C|Boulware, David|Cheng, Jin Q|Coppola, Domenico
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Journal: J Endocrinol. 2003 Dec;179(3):405-15.
Title: Interleukin-1beta (IL-1beta) and IL-6 modulate insulin-like growth factor-binding protein (IGFBP) secretion in colon cancer epithelial (Caco-2) cells.
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Journal: Horm Metab Res. 2003 Nov-Dec;35(11-12):712-25.
Title: Acromegaly and colorectal cancer: a comprehensive review of epidemiology, biological mechanisms, and clinical implications.
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Journal: Horm Metab Res. 2003 Nov-Dec;35(11-12):850-6.
Title: Inhibition of the biologic response to insulin-like growth factor I in MCF-7 breast cancer cells by a new monoclonal antibody to the insulin-like growth factor-I receptor. The importance of receptor down-regulation.
Author: Jackson-Booth, P-G|Terry, C|Lackey, B|Lopaczynska, M|Nissley, P
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Journal: Hepatogastroenterology. 2003 Dec;50 Suppl 2:cclvi-cclx.
Title: Increased fasting serum levels of growth hormone and gastrin in patients with gastric and large bowel cancer.
Author: Triantafillidis, John K|Merikas, Emmanuel|Govosdis, Vasillios|Konstandellou, Evangelia|Cheracakis, Petros|Barbatzas, Charalambos|Tzourmakliotis, Dimitrios|Peros, George
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Journal: Cancer Res. 2004 Jan 15;64(2):665-71.
Title: Matrix metalloproteinase-7 facilitates insulin-like growth factor bioavailability through its proteinase activity on insulin-like growth factor binding protein 3.
Author: Miyamoto, Shin'ichi|Yano, Keiichi|Sugimoto, Seiji|Ishii, Genichiro|Hasebe, Takahiro|Endoh, Yasushi|Kodama, Keiji|Goya, Masato|Chiba, Tsutomu|Ochiai, Atsushi
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Journal: Oncogene. 2004 Feb 12;23(6):1177-86.
Title: Alpha-catenin is required for IGF-I-induced cellular migration but not invasion in human colonic cancer cells.
Author: Andre, Frederic|Janssens, Barbara|Bruyneel, Erik|van Roy, Frans|Gespach, Christian|Mareel, Marc|Bracke, Marc
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Journal: Cancer Res. 2004 Mar 1;64(5):1600-3.
Title: Insulin-like growth factor (IGF)-binding protein-4 inhibits colony formation of colorectal cancer cells by IGF-independent mechanisms.
Author: Diehl, Daniela|Hoeflich, Andreas|Wolf, Eckhard|Lahm, Harald
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Journal: Cancer Epidemiol Biomarkers Prev. 2004 Apr;13(4):538-45.
Title: Aspirin, NSAIDs, and colorectal cancer: possible involvement in an insulin-related pathway.
Author: Slattery, Martha L|Samowitz, Wade|Hoffman, Michael|Ma, Khi Ne|Levin, Theodore R|Neuhausen, Susan
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Journal: J Natl Cancer Inst. 2004 Apr 7;96(7):546-53.
Title: A prospective study of plasma C-peptide and colorectal cancer risk in men.
Author: Ma, Jing|Giovannucci, Edward|Pollak, Michael|Leavitt, Azita|Tao, Yuzhen|Gaziano, J Michael|Stampfer, Meir J
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Journal: Endocrinology. 2004 Aug;145(8):3769-77. Epub 2004 May 6.
Title: Transcriptional activation of the insulin-like growth factor I receptor gene by the Kruppel-like factor 6 (KLF6) tumor suppressor protein: potential interactions between KLF6 and p53.
Author: Rubinstein, Moran|Idelman, Gila|Plymate, Stephen R|Narla, Goutham|Friedman, Scott L|Werner, Haim
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Journal: Drug Saf. 2004;27(6):369-82.
Title: Cancer risk following growth hormone use in childhood: implications for current practice.
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Journal: Cancer Epidemiol Biomarkers Prev. 2004 Jul;13(7):1206-14.
Title: Associations among IRS1, IRS2, IGF1, and IGFBP3 genetic polymorphisms and colorectal cancer.
Author: Slattery, Martha L|Samowitz, Wade|Curtin, Karen|Ma, Khe Ni|Hoffman, Michael|Caan, Bette|Neuhausen, Susan
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Journal: Cancer Epidemiol Biomarkers Prev. 2004 Sep;13(9):1444-51.
Title: Dietary and lifestyle correlates of plasma insulin-like growth factor-I (IGF-I) and IGF binding protein-3 (IGFBP-3): the multiethnic cohort.
Author: DeLellis, Katherine|Rinaldi, Sabina|Kaaks, Rudolph J|Kolonel, Laurence N|Henderson, Brian|Le Marchand, Loic
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Journal: J Mol Endocrinol. 2004 Oct;33(2):377-86.
Title: Contributions of the N- and C-terminal domains of IGF binding protein-6 to IGF binding.
Author: Headey, Stephen J|Leeding, Kerri S|Norton, Raymond S|Bach, Leon A
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Journal: Novartis Found Symp. 2004;262:247-60; discussion 260-68.
Title: Nutrition, insulin, IGF-1 metabolism and cancer risk: a summary of epidemiological evidence.
Author: Kaaks, Rudolf
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Journal: Clin Cancer Res. 2004 Dec 1;10(23):7950-7.
Title: Interplay of insulin-like growth factor-II, insulin-like growth factor-I, insulin-like growth factor-I receptor, COX-2, and matrix metalloproteinase-7, play key roles in the early stage of colorectal carcinogenesis.
Author: Nosho, Katsuhiko|Yamamoto, Hiroyuki|Taniguchi, Hiroaki|Adachi, Yasushi|Yoshida, Yukinari|Arimura, Yoshiaki|Endo, Takao|Hinoda, Yuji|Imai, Kohzoh
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Journal: Ann N Y Acad Sci. 2004 Dec;1030:377-83.
Title: Expression of the insulin-like growth factor-I receptor and proapoptotic Bax and Bak proteins in human colorectal cancer.
Author: Koda, Mariusz|Reszec, Joanna|Sulkowska, Mariola|Kanczuga-Koda, Luiza|Sulkowski, Stanislaw
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Journal: Anticancer Res. 2004 Nov-Dec;24(6):3735-42.
Title: Growth hormone receptor antagonist administration inhibits growth of human colorectal carcinoma in nude mice.
Author: Dagnaes-Hansen, F|Duan, H|Rasmussen, L M|Friend, K E|Flyvbjerg, A
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Journal: Horm Res. 2004;62 Suppl 1:108-15.
Title: Acromegaly and cancer.
Author: Jenkins, Paul J
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Journal: J Clin Endocrinol Metab. 2005 Jan;90(1):84-90.
Title: Colonoscopic screening and follow-up in patients with acromegaly: a multicenter study in Italy.
Author: Terzolo, Massimo|Reimondo, Giuseppe|Gasperi, Maurizio|Cozzi, Renato|Pivonello, Rosario|Vitale, Giovanni|Scillitani, Alfredo|Attanasio, Roberto|Cecconi, Elisabetta|Daffara, Fulvia|Gaia, Ezio|Martino, Ennio|Lombardi, Gaetano|Angeli, Alberto|Colao, Annamaria
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Journal: Oncogene. 2005 Feb 17;24(8):1338-47.
Title: Caveolin-1 inhibits cell detachment-induced p53 activation and anoikis by upregulation of insulin-like growth factor-I receptors and signaling.
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Journal: Int J Colorectal Dis. 2005 May;20(3):203-20.
Title: The role of the insulin-like growth factor system in colorectal cancer: review of current knowledge.
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Journal: Cancer Epidemiol Biomarkers Prev. 2005 Jan;14(1):144-51.
Title: A new single nucleotide polymorphism in the insulin-like growth factor I regulatory region associates with colorectal cancer risk in singapore chinese.
Author: Wong, Hui-Lee|Delellis, Katherine|Probst-Hensch, Nicole|Koh, Woon-Puay|Van Den Berg, David|Lee, Hin-Peng|Yu, Mimi C|Ingles, Sue A
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Journal: Int J Cancer. 2005 May 20;115(1):148-54.
Title: Energy balance, insulin-related genes and risk of colon and rectal cancer.
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Journal: Cancer Res. 2005 Mar 15;65(6):2085-8.
Title: Activated Ras enhances insulin-like growth factor I induction of vascular endothelial growth factor in prostate epithelial cells.
Author: Stearns, Mark|Tran, Jordan|Francis, Mary Kay|Zhang, Hong|Sell, Christian
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166.
Journal: Cancer. 2005 May 15;103(10):2189-98.
Title: Body composition and time course changes in regional distribution of fat and lean tissue in unselected cancer patients on palliative care--correlations with food intake, metabolism, exercise capacity, and hormones.
Author: Fouladiun, Marita|Korner, Ulla|Bosaeus, Ingvar|Daneryd, Peter|Hyltander, Anders|Lundholm, Kent G
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167.
Journal: Cancer Epidemiol Biomarkers Prev. 2005 Apr;14(4):850-5.
Title: A prospective study of C-peptide, insulin-like growth factor-I, insulin-like growth factor binding protein-1, and the risk of colorectal cancer in women.
Author: Wei, Esther K|Ma, Jing|Pollak, Michael N|Rifai, Nader|Fuchs, Charles S|Hankinson, Susan E|Giovannucci, Edward
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Journal: Ann Surg. 2005 May;241(5):748-56; discussion 756-8.
Title: Insulinlike growth factor-I-mediated migration and invasion of human colon carcinoma cells requires activation of c-Met and urokinase plasminogen activator receptor.
Author: Bauer, Todd W|Fan, Fan|Liu, Wenbiao|Johnson, Marjorie|Parikh, Nila U|Parry, Graham C|Callahan, Jennifer|Mazar, Andrew P|Gallick, Gary E|Ellis, Lee M
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Journal: Clin Cancer Res. 2005 May 1;11(9):3494-502.
Title: Blockade of paracrine supply of insulin-like growth factors using neutralizing antibodies suppresses the liver metastasis of human colorectal cancers.
Author: Miyamoto, Shin'ichi|Nakamura, Michio|Shitara, Kenya|Nakamura, Kazuyasu|Ohki, Yuji|Ishii, Genichiro|Goya, Masato|Kodama, Keiji|Sangai, Takafumi|Maeda, Hiroyuki|Shi-Chuang, Zhang|Chiba, Tsutomu|Ochiai, Atsushi
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170.
Journal: Cancer Epidemiol Biomarkers Prev. 2005 May;14(5):1204-11.
Title: Insulin-like growth factor polymorphisms and colorectal cancer risk.
Author: Morimoto, Libby M|Newcomb, Polly A|White, Emily|Bigler, Jeannette|Potter, John D
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Journal: Cancer Epidemiol Biomarkers Prev. 2005 May;14(5):1319-21.
Title: Association of an exon 1 polymorphism in the IGFBP3 gene with circulating IGFBP-3 levels and colorectal cancer risk: the multiethnic cohort study.
Author: Le Marchand, Loic|Kolonel, Laurence N|Henderson, Brian E|Wilkens, Lynne R
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Journal: Zhonghua Liu Xing Bing Xue Za Zhi. 2005 Feb;26(2):132-4.
Title: [Study on the relations between serum insulin-like growth factor-1, insulin-like growth factor binding protein-3 and colorectal cancer: a meta-analysis].
Author: Duan, Qiong-hong|Wang, Zhi-gang|Zhu, Gui-bao|Lu, Zu-xun|Shi, Lv-yuan|Nie, Shao-fa
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Journal: Cancer Epidemiol Biomarkers Prev. 2005 Jun;14(6):1394-401.
Title: Variation in plasma insulin-like growth factor-1 and insulin-like growth factor binding protein-3: genetic factors.
Author: Morimoto, Libby M|Newcomb, Polly A|White, Emily|Bigler, Jeannette|Potter, John D
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Journal: Cancer Epidemiol Biomarkers Prev. 2005 Jun;14(6):1402-10.
Title: Associations between plasma insulin-like growth factor proteins and C-peptide and quality of life in patients with metastatic colorectal cancer.
Author: Meyerhardt, Jeffrey A|Sloan, Jeffrey A|Sargent, Daniel J|Goldberg, Richard M|Pollak, Michael|Morton, Roscoe F|Ramanathan, Ramesh K|Williamson, Stephen K|Findlay, Brian P|Fuchs, Charles S
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Journal: Endocr Relat Cancer. 2005 Jun;12(2):455-69.
Title: ERbeta is a potent inhibitor of cell proliferation in the HCT8 human colon cancer cell line through regulation of cell cycle components.
Author: Martineti, Valentina|Picariello, Lucia|Tognarini, Isabella|Carbonell Sala, Silvia|Gozzini, Alessia|Azzari, Chiara|Mavilia, Carmelo|Tanini, Annalisa|Falchetti, Alberto|Fiorelli, Gianna|Tonelli, Francesco|Brandi, Maria Luisa
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Journal: Br J Nutr. 2005 Jun;93(6):853-8.
Title: Change of the growth hormone-insulin-like growth factor-I axis in patients with gastrointestinal cancer: related to tumour type and nutritional status.
Author: Huang, Qi|Nai, Yong-Jun|Jiang, Zhi-Wei|Li, Jie-Shou
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Journal: Cancer Epidemiol Biomarkers Prev. 2005 Jul;14(7):1646-52.
Title: Leptin, insulin-like growth factor-1, and insulin-like growth factor-2 are mitogens in ApcMin/+ but not Apc+/+ colonic epithelial cell lines.
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Journal: Oncogene. 2005 Oct 20;24(46):6936-44.
Title: ARK5 is transcriptionally regulated by the Large-MAF family and mediates IGF-1-induced cell invasion in multiple myeloma: ARK5 as a new molecular determinant of malignant multiple myeloma.
Author: Suzuki, Atsushi|Iida, Shinsuke|Kato-Uranishi, Miyuki|Tajima, Emi|Zhan, Fenghuang|Hanamura, Ichiro|Huang, Yongsheng|Ogura, Tsutomu|Takahashi, Satoru|Ueda, Ryuzo|Barlogie, Bart|Shaughnessy, John Jr|Esumi, Hiroyasu
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Journal: Biochem Biophys Res Commun. 2005 Sep 2;334(3):947-53.
Title: EGCG inhibits activation of the insulin-like growth factor-1 receptor in human colon cancer cells.
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Journal: Gastroenterology. 2005 Aug;129(2):464-75.
Title: Insulin-like growth factor-I and insulin are associated with the presence and advancement of adenomatous polyps.
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Journal: J Endocrinol Invest. 2005;28(5 Suppl):19-22.
Title: Studies involving the GH-IGF axis: Lessons from IGF-I and IGF-I receptor gene targeting mouse models.
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Journal: Am J Pathol. 2005 Sep;167(3):761-73.
Title: Membrane rafts segregate pro- from anti-apoptotic insulin-like growth factor-I receptor signaling in colon carcinoma cells stimulated by members of the tumor necrosis factor superfamily.
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Title: Variation in plasma insulin-like growth factor-1 and insulin-like growth factor binding protein-3: personal and lifestyle factors (United States).
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Journal: FEBS Lett. 2005 Sep 26;579(23):5123-8.
Title: Comparison of phosphatidylinositol-3-kinase signalling within a panel of human colorectal cancer cell lines with mutant or wild-type PIK3CA.
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Journal: Cancer Epidemiol Biomarkers Prev. 2005 Sep;14(9):2076-81.
Title: Insulin resistance, apoptosis, and colorectal adenoma risk.
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Journal: Endocr Relat Cancer. 2005 Dec;12(4):891-901.
Title: Differential expression of IGF-binding protein-3 in normal and malignant colon and its influence on apoptosis.
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Journal: J Med Food. 2005 Winter;8(4):431-8.
Title: Genistein inhibits insulin-like growth factor-I receptor signaling in HT-29 human colon cancer cells: a possible mechanism of the growth inhibitory effect of Genistein.
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Journal: Gut. 2006 May;55(5):689-94. Epub 2005 Nov 18.
Title: Physical activity, insulin-like growth factor 1, insulin-like growth factor binding protein 3, and survival from colorectal cancer.
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Journal: Endocrinology. 2006 Apr;147(4):1830-7.
Title: Hyperinsulinemia, but not other factors associated with insulin resistance, acutely enhances colorectal epithelial proliferation in vivo.
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Journal: Neoplasma. 2006;53(1):43-8.
Title: P53 correlates positively with VEGF in preoperative sera of colorectal cancer patients.
Author: Famulski, W|Sulkowska, M|Wincewicz, A|Kedra, B|Pawlak, K|Zalewski, B|Sulkowski, S|Koda, M|Baltaziak, M
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Journal: J Natl Cancer Inst. 2006 Jan 18;98(2):139-43.
Title: IGF1 gene polymorphism and risk for hereditary nonpolyposis colorectal cancer.
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Journal: Mutat Res. 2006 Mar 20;595(1-2):117-24.
Title: Polymorphisms in insulin-related genes predispose to specific KRAS2 and TP53 mutations in colon cancer.
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Title: NDR2 acts as the upstream kinase of ARK5 during insulin-like growth factor-1 signaling.
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Title: PPARgamma and colon and rectal cancer: associations with specific tumor mutations, aspirin, ibuprofen and insulin-related genes (United States).
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Journal: Comb Chem High Throughput Screen. 2006 Mar;9(3):163-70.
Title: Antagonists of growth hormone-releasing hormone in oncology.
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Title: Pilot study of oral silibinin, a putative chemopreventive agent, in colorectal cancer patients: silibinin levels in plasma, colorectum, and liver and their pharmacodynamic consequences.
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Journal: Int J Oncol. 2006 Jun;28(6):1317-25.
Title: Biology of insulin-like growth factor binding protein-4 and its role in cancer (review).
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Journal: J Gastroenterol Hepatol. 2006 Jan;21(1 Pt 1):84-91.
Title: Fas-associated phosphatase-1 promotes Fas-mediated apoptosis in human colon cancer cells: novel function of FAP-1.
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Title: Folic acid and its metabolites modulate IGF-I receptor gene expression in colon cancer cells in a p53-dependent manner.
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Journal: Proteins. 2006 Aug 15;64(3):758-68.
Title: Computational model for the IGF-II/IGF2r complex that is predictive of mutational and surface plasmon resonance data.
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Title: Insulin-like growth factors and cancer: no role in screening. Evidence from the BUPA study and meta-analysis of prospective epidemiological studies.
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Title: Carbohydrate digestibility predicts colon carcinogenesis in azoxymethane-treated rats.
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Journal: Neuroendocrinology. 2006;83(3-4):218-23. Epub 2006 Oct 13.
Title: Cancers associated with acromegaly.
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Title: [Colorectal carcinoma screening in patients with type 2 diabetes mellitus].
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Journal: Ann N Y Acad Sci. 2006 Dec;1090:265-75.
Title: Insulin-like growth factor-I receptor correlates with connexin 26 and Bcl-xL expression in human colorectal cancer.
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Journal: J Nutr. 2007 Feb;137(2):379-83.
Title: Isolated isoflavones do not affect the circulating insulin-like growth factor system in men at increased colorectal cancer risk.
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Title: Plasma C-peptide, insulin-like growth factor-I, insulin-like growth factor binding proteins and risk of colorectal cancer in a nested case-control study: the Japan public health center-based prospective study.
Author: Otani, Tetsuya|Iwasaki, Motoki|Sasazuki, Shizuka|Inoue, Manami|Tsugane, Shoichiro
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Journal: Clin Cancer Res. 2007 Feb 1;13(3):1000-9.
Title: Clinical pharmacodynamic effects of the growth hormone receptor antagonist pegvisomant: implications for cancer therapy.
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Journal: Int J Cancer. 2007 Jul 15;121(2):368-76.
Title: Serum C-peptide, IGFBP-1 and IGFBP-2 and risk of colon and rectal cancers in the European Prospective Investigation into Cancer and Nutrition.
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Journal: Eur J Pharmacol. 2007 May 7;562(1-2):1-11.
Title: ATP non-competitive IGF-1 receptor kinase inhibitors as lead anti-neoplastic and anti-papilloma agents.
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Journal: Cancer Epidemiol Biomarkers Prev. 2007 Apr;16(4):716-22.
Title: Insulin-like growth factor-I and risk of high-grade cervical intraepithelial neoplasia.
Author: Schaffer, Andrea|Koushik, Anita|Trottier, Helen|Duarte-Franco, Eliane|Mansour, Nabil|Arseneau, Jocelyne|Provencher, Diane|Gilbert, Lucy|Gotlieb, Walter|Ferenczy, Alex|Coutlee, Francois|Pollak, Michael N|Franco, Eduardo L
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Journal: Curr Alzheimer Res. 2007 Apr;4(2):213-7.
Title: Gestational programming of offspring obesity: a potential contributor to Alzheimer's disease.
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Journal: Hum Pathol. 2007 Jul;38(7):1037-46.
Title: Insulinlike growth factor I receptor and estrogen receptor beta expressions are inversely correlated in colorectal neoplasms and affected by the insulin resistance syndrome.
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Journal: J Gastroenterol. 2007 Apr;42(4):267-74.
Title: Metabolic syndrome and gastrointestinal diseases.
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Journal: J Biol Chem. 2007 Aug 3;282(31):22298-306.
Title: Promotion of cancer cell migration: an insulin-like growth factor (IGF)-independent action of IGF-binding protein-6.
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Journal: Eur J Cancer Prev. 2007 Aug;16(4):298-303.
Title: Tomato lycopene extract supplementation decreases insulin-like growth factor-I levels in colon cancer patients.
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Journal: Arch Med Res. 2007 Jul;38(5):519-25.
Title: Role of insulin-like growth factor-1 in colon cancerogenesis: a case-control study.
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Journal: Cancer Causes Control. 2007 Oct;18(8):853-63.
Title: Dietary carbohydrate, glycemic index, and glycemic load and the risk of colorectal cancer in the BCDDP cohort.
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Journal: Am J Physiol Gastrointest Liver Physiol. 2007 Oct;293(4):G673-81.
Title: PGE2 inhibits apoptosis in human adenocarcinoma Caco-2 cell line through Ras-PI3K association and cAMP-dependent kinase A activation.
Author: Leone, Vincenza|di Palma, Antonella|Ricchi, Paolo|Acquaviva, Fabio|Giannouli, Maria|Di Prisco, Anna Maria|Iuliano, Francesca|Acquaviva, Angela M
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Journal: Ann Surg Oncol. 2007 Oct;14(10):2838-46. Epub 2007 Jul 26.
Title: Targeting of insulin-like growth factor-I receptor with a monoclonal antibody inhibits growth of hepatic metastases from human colon carcinoma in mice.
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Journal: Mol Cancer Ther. 2007 Aug;6(8):2158-67. Epub 2007 Aug 1.
Title: A novel, potent, and selective insulin-like growth factor-I receptor kinase inhibitor blocks insulin-like growth factor-I receptor signaling in vitro and inhibits insulin-like growth factor-I receptor dependent tumor growth in vivo.
Author: Ji, Qun-sheng|Mulvihill, Mark J|Rosenfeld-Franklin, Maryland|Cooke, Andrew|Feng, Lixin|Mak, Gilda|O'Connor, Matthew|Yao, Yan|Pirritt, Caroline|Buck, Elizabeth|Eyzaguirre, Alexandra|Arnold, Lee D|Gibson, Neil W|Pachter, Jonathan A
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Journal: Pol Merkur Lekarski. 2007 May;22(131):373-5.
Title: [Serum concentration of insulin, C-peptide and insulin-like growth factor I in patients with colon adenomas and colorectal cancer].
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Journal: Colorectal Dis. 2007 Sep;9(7):625-31.
Title: Increased apoptosis and decreased proliferation of colorectal cancer cells using insulin-like growth factor binding protein-4 gene delivered locally by gene transfer.
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Journal: J Endocrinol. 2007 Oct;195(1):79-87.
Title: Fetal programming of colon cancer in adult rats: correlations with altered neonatal growth trajectory, circulating IGF-I and IGF binding proteins, and testosterone.
Author: Xiao, Rijin|Hennings, Leah J|Badger, Thomas M|Simmen, Frank A
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Journal: Am J Clin Nutr. 2007 Nov;86(5):1456-62.
Title: Lycopene supplementation elevates circulating insulin-like growth factor binding protein-1 and -2 concentrations in persons at greater risk of colorectal cancer.
Author: Vrieling, Alina|Voskuil, Dorien W|Bonfrer, Johannes M|Korse, Catharina M|van Doorn, Jaap|Cats, Annemieke|Depla, Annekatrien C|Timmer, Robin|Witteman, Ben J|van Leeuwen, Flora E|Van't Veer, Laura J|Rookus, Matti A|Kampman, Ellen
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Journal: Cancer Detect Prev. 2007;31(5):408-16. Epub 2007 Nov 26.
Title: Polymorphisms in the insulin like growth factor 1 and IGF binding protein 3 genes and risk of colorectal cancer.
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Journal: Proc Natl Acad Sci U S A. 2007 Dec 26;104(52):20926-31.
Title: Enhanced sensitivity to IGF-II signaling links loss of imprinting of IGF2 to increased cell proliferation and tumor risk.
Author: Kaneda, Atsushi|Wang, Chiaochun J|Cheong, Raymond|Timp, Winston|Onyango, Patrick|Wen, Bo|Iacobuzio-Donahue, Christine A|Ohlsson, Rolf|Andraos, Rita|Pearson, Mark A|Sharov, Alexei A|Longo, Dan L|Ko, Minoru S H|Levchenko, Andre|Feinberg, Andrew P
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Journal: J Sports Sci Med. 2007 Dec 1;6(4):434-40. eCollection 2007.
Title: IGF-1 Gene Expression in Rat Colonic Mucosa After Different Exercise Volumes.
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Journal: Mol Carcinog. 2008 Jan;47(1):9-21.
Title: Microarray analysis reveals that leptin induces autocrine/paracrine cascades to promote survival and proliferation of colon epithelial cells in an Apc genotype-dependent fashion.
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Journal: Int J Cancer. 2008 Jan 15;122(2):472-6.
Title: Colon carcinogenesis in liver-specific IGF-I-deficient (LID) mice.
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Journal: Int J Cancer. 2008 Jan 15;122(2):267-73.
Title: Curcumin enhances the effects of 5-fluorouracil and oxaliplatin in mediating growth inhibition of colon cancer cells by modulating EGFR and IGF-1R.
Author: Patel, Bhaumik B|Sengupta, Radha|Qazi, Sadia|Vachhani, Hetal|Yu, Yingjie|Rishi, Arun K|Majumdar, Adhip P N
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Journal: Growth Horm IGF Res. 2008 Jun;18(3):198-204.
Title: Assessing the potential usefulness of IGF-related peptides and adiponectin for predicting disease risk.
Author: Belobrajdic, Damien P|Priebe, Ilka K|Forbes, Briony|Flyvbjerg, Allan|Chen, Jian-Wen|Cosgrove, Leah J|Frystyk, Jan|Saunders, Ian W
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Journal: Int J Cancer. 2008 Feb 1;122(3):572-82.
Title: Insulin-like growth factor-I receptor, E-cadherin and alpha v integrin form a dynamic complex under the control of alpha-catenin.
Author: Canonici, Alexandra|Steelant, Wim|Rigot, Veronique|Khomitch-Baud, Alexandra|Boutaghou-Cherid, Hikma|Bruyneel, Erik|Van Roy, Frans|Garrouste, Francoise|Pommier, Gilbert|Andre, Frederic
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Journal: Fertil Steril. 2008 Oct;90(4):1236-9.
Title: Increased insulin-like growth factor-1 after oophorectomy in postmenopausal women.
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Journal: Int J Cancer. 2008 Apr 1;122(7):1611-7.
Title: Leptin and leptin receptor genotypes and colon cancer: gene-gene and gene-lifestyle interactions.
Author: Slattery, Martha L|Wolff, Roger K|Herrick, Jennifer|Caan, Bette J|Potter, John D
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Journal: J Clin Invest. 2008 Jan;118(1):352-63.
Title: Selective inhibition of proprotein convertases represses the metastatic potential of human colorectal tumor cells.
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Journal: Rev Endocr Metab Disord. 2008 Mar;9(1):33-9.
Title: Does acromegaly enhance mortality?
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Journal: Nat Clin Pract Endocrinol Metab. 2008 Jan;4(1):33-43.
Title: Antagonists of growth-hormone-releasing hormone: an emerging new therapy for cancer.
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Title: Acromegaly: re-thinking the cancer risk.
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Journal: Cancer Res. 2008 Jan 1;68(1):329-37.
Title: Insulin, insulin-like growth factor-I, endogenous estradiol, and risk of colorectal cancer in postmenopausal women.
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Title: Insulin-like growth factor-i regulates Kruppel-like factor-6 gene expression in a p53-dependent manner.
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Title: IGF-I (CA) repeat polymorphisms and risk of cancer: a meta-analysis.
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Journal: Neoplasma. 2008;55(2):138-42.
Title: Tumor markers in staging and prognosis of colorectal carcinoma.
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Title: Plasma insulin-like growth factor I is inversely associated with colorectal adenoma recurrence: a novel hypothesis.
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Journal: Clin Gastroenterol Hepatol. 2008 Mar;6(3):360-3.
Title: Anti-aging therapy with human growth hormone associated with metastatic colon cancer in a patient with Crohn's colitis.
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Journal: Mol Cancer. 2008 Feb 8;7:17.
Title: Inducing apoptosis of human colon cancer cells by an IGF-I D domain analogue peptide.
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Title: Inhibition of colon cancer cell growth by dietary components: role of the insulin-like growth factor (IGF) system.
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Journal: Gut. 2008 Aug;57(8):1090-6.
Title: Insulin-like growth factor-1 promoter polymorphisms and colorectal cancer: a functional genomics approach.
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Journal: Nutr Cancer. 2008;60(1):61-8.
Title: Low-carbohydrate diet versus caloric restriction: effects on weight loss, hormones, and colon tumor growth in obese mice.
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Title: Type 2 diabetes mellitus as risk factor for colorectal cancer.
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Journal: BMC Cancer. 2008 May 22;8:143.
Title: Local IGFBP-3 mRNA expression, apoptosis and risk of colorectal adenomas.
Author: Keku, Temitope O|Sandler, Robert S|Simmons, James G|Galanko, Joseph|Woosley, John T|Proffitt, Michelle|Omofoye, Oluwaseun|McDoom, Maya|Lund, Pauline K
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Journal: Growth Horm IGF Res. 2008 Dec;18(6):487-96.
Title: Recombinant human insulin-like growth factor-binding protein 3 inhibits tumor growth and targets the Akt pathway in lung and colon cancer models.
Author: Alami, Nezha|Page, Viviane|Yu, Qingnan|Jerome, Lori|Paterson, Jesse|Shiry, Laura|Leyland-Jones, Brian
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Journal: Cancer Epidemiol Biomarkers Prev. 2008 Jun;17(6):1493-8.
Title: Serum concentrations of insulin-like growth factor and insulin-like growth factor binding protein 3 and recurrent colorectal adenomas.
Author: Flood, Andrew|Mai, Volker|Pfeiffer, Ruth|Kahle, Lisa|Rosen, Clifford J|Lanza, Elaine|Schatzkin, Arthur
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Journal: Int J Cancer. 2008 Sep 15;123(6):1339-43.
Title: IGF1 is a modifier of disease risk in hereditary non-polyposis colorectal cancer.
Author: Reeves, Stuart G|Rich, Dominique|Meldrum, Cliff J|Colyvas, Kim|Kurzawski, Grzegorz|Suchy, Janina|Lubinski, Jan|Scott, Rodney J
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Journal: Cancer Epidemiol Biomarkers Prev. 2008 Jul;17(7):1832-4.
Title: IGF-I, IGFBP-3, and IGF-I/IGFBP-3 ratio: no association with incident colorectal cancer in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study.
Author: Max, Joshua B|Limburg, Paul J|Ogunseitan, Adeboye|Stolzenberg-Solomon, Rachael Z|Vierkant, Robert A|Pollak, Michael J|Sellers, Thomas A|Virtamo, Jarmo|Cerhan, James R|Albanes, Demetrius
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Journal: Oncol Rep. 2008 Aug;20(2):359-64.
Title: Clinicopathological significance of the gene expression of matrix metalloproteinase-7, insulin-like growth factor-1, insulin-like growth factor-2 and insulin-like growth factor-1 receptor in patients with colorectal cancer: insulin-like growth factor-1 re
Author: Oshima, Takashi|Akaike, Makoto|Yoshihara, Kazue|Shiozawa, Manabu|Yamamoto, Naoto|Sato, Tsutomu|Yamada, Roppei|Fujii, Shoich|Rino, Yasushi|Kunisaki, Chikara|Tanaka, Katsuaki|Masuda, Munetaka|Imada, Toshio
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257.
Journal: Cancer Epidemiol Biomarkers Prev. 2008 Oct;17(10):2585-93.
Title: No effect of red clover-derived isoflavone intervention on the insulin-like growth factor system in women at increased risk of colorectal cancer.
Author: Vrieling, Alina|Rookus, Matti A|Kampman, Ellen|Bonfrer, Johannes M G|Bosma, Astrid|Cats, Annemieke|van Doorn, Jaap|Korse, Catharina M|Witteman, Ben J M|van Leeuwen, Flora E|van't Veer, Laura J|Voskuil, Dorien W
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Journal: Cancer Epidemiol Biomarkers Prev. 2008 Oct;17(10):2835-45.
Title: Diagnostic mRNA expression patterns of inflamed, benign, and malignant colorectal biopsy specimen and their correlation with peripheral blood results.
Author: Galamb, Orsolya|Sipos, Ferenc|Solymosi, Norbert|Spisak, Sandor|Krenacs, Tibor|Toth, Kinga|Tulassay, Zsolt|Molnar, Bela
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Journal: BMC Cancer. 2008 Nov 2;8:316.
Title: Voluntary exercise inhibits intestinal tumorigenesis in Apc(Min/+) mice and azoxymethane/dextran sulfate sodium-treated mice.
Author: Ju, Jihyeung|Nolan, Bonnie|Cheh, Michelle|Bose, Mousumi|Lin, Yong|Wagner, George C|Yang, Chung S
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Journal: Cancer Epidemiol Biomarkers Prev. 2008 Dec;17(12):3314-8.
Title: Recreational physical activity modifies the association between a common GH1 polymorphism and colorectal cancer risk.
Author: Khoury-Shakour, Sana|Gruber, Stephen B|Lejbkowicz, Flavio|Rennert, Hedy S|Raskin, Leon|Pinchev, Mila|Rennert, Gad
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Journal: Clin Cancer Res. 2008 Dec 15;14(24):8263-9.
Title: Plasma insulin-like growth factors, insulin-like binding protein-3, and outcome in metastatic colorectal cancer: results from intergroup trial N9741.
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Journal: Cancer Prev Res (Phila). 2008 Sep;1(4):298-304.
Title: (-)-Epigallocatechin gallate suppresses azoxymethane-induced colonic premalignant lesions in male C57BL/KsJ-db/db mice.
Author: Shimizu, Masahito|Shirakami, Yohei|Sakai, Hiroyasu|Adachi, Seiji|Hata, Kazuya|Hirose, Yoshinobu|Tsurumi, Hisashi|Tanaka, Takuji|Moriwaki, Hisataka
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Journal: Growth Horm IGF Res. 2009 Apr;19(2):126-35.
Title: Expression of insulin-like growth factor system components in colorectal tissue and its relation with serum IGF levels.
Author: Vrieling, Alina|Voskuil, Dorien W|Bosma, Astrid|Majoor, Donne M|van Doorn, Jaap|Cats, Annemieke|Depla, Annekatrien C T M|Timmer, Robin|Witteman, Ben J M|Wesseling, Jelle|Kampman, Ellen|Van't Veer, Laura J
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Journal: J Clin Oncol. 2009 Jan 10;27(2):176-85.
Title: Insulin, the insulin-like growth factor axis, and mortality in patients with nonmetastatic colorectal cancer.
Author: Wolpin, Brian M|Meyerhardt, Jeffrey A|Chan, Andrew T|Ng, Kimmie|Chan, Jennifer A|Wu, Kana|Pollak, Michael N|Giovannucci, Edward L|Fuchs, Charles S
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Journal: Cancer Causes Control. 2009 Jul;20(5):653-61.
Title: Number of aberrant crypt foci associated with adiposity and IGF1 bioavailability.
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Journal: Endocr Relat Cancer. 2009 Mar;16(1):311-7.
Title: Serum IGF-I, IGFBP-3, and matrix metalloproteinase-7 levels and acquired chemo-resistance in advanced colorectal cancer.
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Journal: Nutr Cancer. 2009;61(1):81-93.
Title: High sucrose diets promote intestinal epithelial cell proliferation and tumorigenesis in APC(Min) mice by increasing insulin and IGF-I levels.
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Title: Dietary carbohydrate source alters gene expression profile of intestinal epithelium in mice.
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Journal: Diabetes Metab Res Rev. 2009 Jan;25(1):41-9.
Title: Insulin analogues display IGF-I-like mitogenic and anti-apoptotic activities in cultured cancer cells.
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Journal: Clin Cancer Res. 2009 May 1;15(9):3068-75.
Title: Supplementation with branched-chain amino acids inhibits azoxymethane-induced colonic preneoplastic lesions in male C57BL/KsJ-db/db mice.
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Journal: Mol Cancer Ther. 2009 Apr;8(4):821-33.
Title: Dual silencing of insulin-like growth factor-I receptor and epidermal growth factor receptor in colorectal cancer cells is associated with decreased proliferation and enhanced apoptosis.
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Journal: Growth Horm IGF Res. 2009 Oct;19(5):447-56.
Title: Reduced susceptibility to azoxymethane-induced aberrant crypt foci formation and colon cancer in growth hormone deficient rats.
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Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2009 May;12(3):264-8.
Title: [Association of insulin, insulin-like growth factor and insulin-like growth factor binding proteins with the risk of colorectal cancer].
Author: Jiang, Bo|Liu, Dong-Bo|Zhang, Xin|DU, Li-Li|Han, Cun-Zhi
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Journal: BMC Cancer. 2009 May 21;9:158.
Title: IGF-I activates caspases 3/7, 8 and 9 but does not induce cell death in colorectal cancer cells.
Author: Yang, Shi Yu|Bolvin, Capucine|Sales, Kevin M|Fuller, Barry|Seifalian, Alexander M|Winslet, Marc C
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Journal: Arch Physiol Biochem. 2009 Jul;115(3):127-36.
Title: Effects of omega-3 and omega-6 fatty acids on IGF-I receptor signalling in colorectal cancer cells.
Author: Seti, Hila|Leikin-Frenkel, Alicia|Werner, Haim
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Journal: Adv Med Sci. 2009;54(1):51-8.
Title: IGF-I, IGF-II, IGFBP2, IGFBP3 and acid-labile subunit (ALS) in colorectal cancer patients before surgery and during one year follow up in relation to age.
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Journal: Eur J Hum Genet. 2009 Dec;17(12):1668-75.
Title: Phenotypes and genotypes of insulin-like growth factor 1, IGF-binding protein-3 and cancer risk: evidence from 96 studies.
Author: Chen, Wensen|Wang, Sumin|Tian, Tian|Bai, Jianling|Hu, Zhibin|Xu, Yan|Dong, Jing|Chen, Feng|Wang, Xinru|Shen, Hongbing
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Journal: Anticancer Res. 2009 Jun;29(6):1999-2007.
Title: Prioritization of EGFR/IGF-IR/VEGFR2 combination targeted therapies utilizing cancer models.
Author: Tonra, James R|Corcoran, Erik|Deevi, Dhanvanthri S|Steiner, Philipp|Kearney, Jessica|Li, Huiling|Ludwig, Dale L|Zhu, Zhenping|Witte, Larry|Surguladze, David|Hicklin, Daniel J
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Journal: Cancer Prev Res (Phila). 2009 Jul;2(7):625-33.
Title: Pilot study of oral anthocyanins for colorectal cancer chemoprevention.
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Journal: Intern Med. 2009;48(15):1273-8. Epub 2009 Aug 3.
Title: Acromegaly associated with multiple tumors.
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Journal: Cancer Causes Control. 2009 Nov;20(9):1769-77.
Title: Genetic variants in the cell cycle control pathways contribute to early onset colorectal cancer in Lynch syndrome.
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Journal: Mol Carcinog. 2009 Dec;48(12):1071-6.
Title: Genetic reduction of circulating insulin-like growth factor-1 inhibits azoxymethane-induced colon tumorigenesis in mice.
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Journal: J Biol Chem. 2009 Nov 13;284(46):32178-87.
Title: Design of an insulin analog with enhanced receptor binding selectivity: rationale, structure, and therapeutic implications.
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Journal: Clin Chem Lab Med. 2009;47(11):1439-45.
Title: Hypoxia related growth factors and p53 in preoperative sera from patients with colorectal cancer--evaluation of the prognostic significance of these agents.
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Title: Obesity management--an opportunity for cancer prevention.
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Journal: Asian Pac J Cancer Prev. 2009 Dec;10 Suppl:29-35.
Title: Association of serum retinol and carotenoids with insulin-like growth factors and insulin-like growth factor binding protein-3 among control subjects of a nested case-control study in the Japan Collaborative Cohort Study.
Author: Suzuki, Koji|Ito, Yoshinori|Hashimoto, Shuji|Kawado, Miyuki|Inoue, Takashi|Ando, Masahiko|Watanabe, Yoshiyuki|Inaba, Yutaka|Tajima, Kazuo|Nakachi, Kei|Tamakoshi, Akiko
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Title: Insulin-like growth factor (IGF)-I, IGF-II, IGF binding protein-3, and risk of colorectal cancer: a nested case-control study in the Japan Collaborative Cohort study.
Author: Suzuki, Sadao|Kojima, Masayo|Tokudome, Shinkan|Suzuki, Koji|Ozasa, Kotaro|Ito, Yoshinori|Inaba, Yutaka|Tajima, Kazuo|Nakachi, Kei|Watanabe, Yoshiyuki|Tamakoshi, Akiko
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Journal: Mol Med Rep. 2009 May-Jun;2(3):339-43.
Title: Correlation of the plasma level of insulin-like growth factor-1 with the number of aberrant crypt foci in male individuals.
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Journal: Cancer Causes Control. 2010 Jan;21(1):91-7.
Title: Association of IGF1 and IGFBP3 polymorphisms with colorectal polyps and colorectal cancer risk.
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Title: Serum levels of IGF-I, IGFBP-3 and colorectal cancer risk: results from the EPIC cohort, plus a meta-analysis of prospective studies.
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Journal: Acta Oncol. 2010;49(1):70-5.
Title: SiRNA-mediated IGF-1R inhibition sensitizes human colon cancer SW480 cells to radiation.
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Title: Insulin-like growth factor-I regulates the liver microenvironment in obese mice and promotes liver metastasis.
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Title: Insulin-like growth factor 1 expression correlates with clinical outcome in K-RAS wild type colorectal cancer patients treated with cetuximab and irinotecan.
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Journal: Endocrinology. 2010 Apr;151(4):1418-27.
Title: Silencing of the insulin receptor isoform A favors formation of type 1 insulin-like growth factor receptor (IGF-IR) homodimers and enhances ligand-induced IGF-IR activation and viability of human colon carcinoma cells.
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Journal: Endokrynol Pol. 2010 Jan-Feb;61(1):29-34.
Title: The prevalence of benign and malignant neoplasms in acromegalic patients.
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Journal: Pituitary. 2010 Sep;13(3):242-8.
Title: Thyroid cancer is the most common cancer associated with acromegaly.
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Title: Decreased levels of plasma adiponectin associated with increased risk of colorectal cancer.
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Title: (-)-Epigallocatechin gallate inhibits growth and activation of the VEGF/VEGFR axis in human colorectal cancer cells.
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Title: Suppressor of cytokine signaling-2 gene disruption promotes Apc(Min/+) tumorigenesis and activator protein-1 activation.
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Title: Effects of dietary beef and chicken with and without high amylose maize starch on blood malondialdehyde, interleukins, IGF-I, insulin, leptin, MMP-2, and TIMP-2 concentrations in rats.
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Title: Inhibition of IGF-1R-dependent PI3K activation sensitizes colon cancer cells specifically to DR5-mediated apoptosis but not to rhTRAIL.
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Title: Human colon cancer stem cells are enriched by insulin-like growth factor-1 and are sensitive to figitumumab.
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Title: Expression of IGF-1 and IGF-1R and their relation to clinicopathological factors in colorectal cancer.
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Title: The regulation of skeletal muscle protein turnover during the progression of cancer cachexia in the Apc(Min/+) mouse.
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Title: miRNA Alterations Modify Kinase Activation In The IGF-1 Pathway And Correlate With Colorectal Cancer Stage And Progression In Patients.
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Title: No Association of Insulin-like Growth Factor Gene Polymorphisms with Survival in Patients with Colorectal Cancer.
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Title: Do insulin-like growth factor associated proteins qualify as a tumor marker? Results of a prospective study in 163 cancer patients.
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Title: Relationships between insulin-like growth factor i and selected clinico-morphological parameters in colorectal cancer patients.
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Title: C57BL/KsJ-db/db-Apc mice exhibit an increased incidence of intestinal neoplasms.
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Title: Interactions between plasma levels of 25-hydroxyvitamin D, insulin-like growth factor (IGF)-1 and C-peptide with risk of colorectal cancer.
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Title: Effects of a 12-week home-based exercise program on the level of physical activity, insulin, and cytokines in colorectal cancer survivors: a pilot study.
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Journal: BMJ Open. 2013 May 28;3(5). pii: e002737.
Title: Mathematical modelling to restore circulating IGF-1 concentrations in children with Crohn's disease-induced growth failure: a pharmacokinetic study.
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Journal: J Int Med Res. 2013 Aug;41(4):1228-35.
Title: The role of insulin-like growth factor 1 and its receptor in the formation and development of colorectal carcinoma.
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Journal: Crit Rev Oncol Hematol. 2013 Nov;88(2):272-83.
Title: Molecular biomarkers of resistance to anti-EGFR treatment in metastatic colorectal cancer, from classical to innovation.
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Journal: Int J Mol Sci. 2013 Aug 22;14(9):17279-303.
Title: Potential targets for colorectal cancer prevention.
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Journal: PLoS One. 2013 Oct 15;8(10):e77516.
Title: Inhibition of human MCF-7 breast cancer cells and HT-29 colon cancer cells by rice-produced recombinant human insulin-like growth binding protein-3 (rhIGFBP-3).
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Journal: Asian Pac J Cancer Prev. 2013;14(9):5011-6.
Title: Is there an association between variants in candidate insulin pathway genes IGF-I, IGFBP-3, INSR, and IRS2 and risk of colorectal cancer in the Iranian population?
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Journal: PLoS One. 2013 Nov 18;8(11):e79710.
Title: Treatment with insulin analog X10 and IGF-1 increases growth of colon cancer allografts.
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Journal: World J Gastroenterol. 2013 Nov 21;19(43):7788-94.
Title: Insulin-like growth factor-1 induces lymphangiogenesis and facilitates lymphatic metastasis in colorectal cancer.
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Journal: Pituitary. 2014 Aug;17(4):299-306.
Title: Increased thyroid cancer risk in acromegaly.
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Journal: Clin Res Hepatol Gastroenterol. 2014 Feb;38(1):99-105.
Title: IGF-I levels and visceral fat accumulation in colonic neoplasia.
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Journal: Cancer Causes Control. 2014 Feb;25(2):161-70.
Title: Racial differences in the association of insulin-like growth factor pathway and colorectal adenoma risk.
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Title: Phase 1b study of safety, tolerability and efficacy of R1507, a monoclonal antibody to IGF-1R in combination with multiple standard oncology regimens in patients with advanced solid malignancies.
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Journal: Oncol Lett. 2014 Feb;7(2):311-320.
Title: Marginal effects of glucose, insulin and insulin-like growth factor on chemotherapy response in endothelial and colorectal cancer cells.
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Journal: Am J Physiol Gastrointest Liver Physiol. 2014 Feb;306(3):G229-43.
Title: Identification of a microRNA landscape targeting the PI3K/Akt signaling pathway in inflammation-induced colorectal carcinogenesis.
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Title: Metabolic syndrome and colorectal cancer: is hyperinsulinemia/insulin receptor-mediated angiogenesis a critical process?
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Title: IGF1R blockade with ganitumab results in systemic effects on the GH-IGF axis in mice.
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Journal: World J Gastroenterol. 2014 Feb 14;20(6):1608-13.
Title: Possible roles of insulin, IGF-1 and IGFBPs in initiation and progression of colorectal cancer.
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Title: Polymorphisms in the insulin-like growth factor axis are associated with gastrointestinal cancer.
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Title: Cytohesins/ARNO: the function in colorectal cancer cells.
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Title: Effects of calorie restriction and diet-induced obesity on murine colon carcinogenesis, growth and inflammatory factors, and microRNA expression.
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Title: mRNA expression of IGF-1 and IGF-1R in patients with colorectal adenocarcinoma and type 2 diabetes.
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Title: Insulin-like growth factors (IGF), IGF-binding proteins (IGFBP), and vascular endothelial growth factor (VEGF) in blood serum of patients with colorectal cancer.
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Title: Quantitative proteome profiling of lymph node-positive vs. -negative colorectal carcinomas pinpoints MX1 as a marker for lymph node metastasis.
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Journal: Eur J Epidemiol. 2014 Apr;29(4):261-75.
Title: Biomarker patterns of inflammatory and metabolic pathways are associated with risk of colorectal cancer: results from the European Prospective Investigation into Cancer and Nutrition (EPIC).
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Title: The insulin-like growth factor axis: A biological mechanism linking physical activity to colorectal cancer survival.
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Title: Effect of a high-fat diet in development of colonic adenoma in an animal model.
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Title: Association of insulin-like growth factor-I receptor polymorphism with colorectal cancer development.
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Title: Carnosic acid suppresses colon tumor formation in association with antiadipogenic activity.
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Title: Colon carcinogenesis: influence of Western diet-induced obesity and targeting stem cells using dietary bioactive compounds.
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Journal: Br J Cancer. 2014 Nov 11;111(10):1932-44.
Title: A parallel-arm phase I trial of the humanised anti-IGF-1R antibody dalotuzumab in combination with the AKT inhibitor MK-2206, the mTOR inhibitor ridaforolimus, or the NOTCH inhibitor MK-0752, in patients with advanced solid tumours.
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Title: Kaempferol Downregulates Insulin-like Growth Factor-I Receptor and ErbB3 Signaling in HT-29 Human Colon Cancer Cells.
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Title: Insulin-like growth factor receptor-1 overexpression is associated with poor response of rectal cancers to radiotherapy.
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Title: MiR-143 and MiR-145 regulate IGF1R to suppress cell proliferation in colorectal cancer.
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Title: [Colorectal neo- and dysplasia in acromegaly].
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Journal: Target Oncol. 2015 Mar;10(1):65-76.
Title: Anticancer activity of the type I insulin-like growth factor receptor antagonist, ganitumab, in combination with the death receptor 5 agonist, conatumumab.
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Title: Insulin-Like Growth Factor-1 Modulates Polycomb Cbx8 Expression and Inhibits Colon Cancer Cell Apoptosis.
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Title: Combined use of vitamin D3 and metformin exhibits synergistic chemopreventive effects on colorectal neoplasia in rats and mice.
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Journal: Mol Cancer Ther. 2015 Feb;14(2):620-30.
Title: IRS2 copy number gain, KRAS and BRAF mutation status as predictive biomarkers for response to the IGF-1R/IR inhibitor BMS-754807 in colorectal cancer cell lines.
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Title: An exon variant in insulin receptor gene is associated with susceptibility to colorectal cancer in women.
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Title: IFN-gamma-mediated IRF1/miR-29b feedback loop suppresses colorectal cancer cell growth and metastasis by repressing IGF1.
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Title: Role of physical activity and sport in oncology: scientific commission of the National Federation Sport and Cancer CAMI.
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Title: ATF3 Mediates Anti-Cancer Activity of Trans-10, cis-12-Conjugated Linoleic Acid in Human Colon Cancer Cells.
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Title: The identification of specific methylation patterns across different cancers.
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Title: Inhibition of insulin-like growth factor receptor/AKT/mammalian target of rapamycin axis targets colorectal cancer stem cells by attenuating mevalonate-isoprenoid pathway in vitro and in vivo.
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Title: Prospective study of a molecular selection profile for RAS wild type colorectal cancer patients receiving irinotecan-cetuximab.
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Title: A male patient with acromegaly and breast cancer: treating acromegaly to control tumor progression.
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Title: Insulin-like Growth Factor-1, IGF-binding Protein-3, C-peptide and Colorectal Cancer: a Case-control Study.
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Title: [Changes in markers of proliferation, neoangiogenesis and plasminogen activation system in rectal cancer tissue].
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Title: Body size, physical activity, genetic variants in the insulin-like growth factor pathway and colorectal cancer risk.
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Title: Crosstalk between the TNF and IGF pathways enhances NF-kappaB activation and signaling in cancer cells.
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Title: Genetic Variants in the Insulin-like Growth Factor Pathway and Colorectal Cancer Risk in the Netherlands Cohort Study.
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Title: Insulin-Like Growth Factor-2 Is Induced Following 5-Aminolevulinic Acid-Mediated Photodynamic Therapy in SW620 Human Colon Cancer Cell Line.
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Journal: Oncol Rep. 2015 Dec;34(6):3203-11.
Title: Antiproliferation effect of evodiamine in human colon cancer cells is associated with IGF-1/HIF-1alpha downregulation.
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Title: The Insulin/IGF System in Colorectal Cancer Development and Resistance to Therapy.
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Journal: Eur J Cancer Prev. 2016 Jan;25(1):41-9.
Title: Comparison of plasma levels of obesity-related biomarkers among Japanese populations in Tokyo, Japan, Sao Paulo, Brazil, and Hawaii, USA.
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Journal: Ann Surg Oncol. 2016 Feb;23 Suppl 2:S266-74.
Title: Visualization of Lymph/Blood Flow in Laparoscopic Colorectal Cancer Surgery by ICG Fluorescence Imaging (Lap-IGFI).
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Title: Targeting colorectal cancer via its microenvironment by inhibiting IGF-1 receptor-insulin receptor substrate and STAT3 signaling.
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Title: Peritumoral adipose tissue as a source of inflammatory and angiogenic factors in colorectal cancer.
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Title: Cinnamaldehyde affects the biological behavior of human colorectal cancer cells and induces apoptosis via inhibition of the PI3K/Akt signaling pathway.
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Title: Male pattern baldness and risk of colorectal neoplasia.
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Title: Phase I Dose-Escalation Study of Linsitinib (OSI-906) and Erlotinib in Patients with Advanced Solid Tumors.
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Title: Preclinical and first-in-human phase I studies of KW-2450, an oral tyrosine kinase inhibitor with insulin-like growth factor receptor-1/insulin receptor selectivity.
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Title: Quantitative analysis of insulin-like growth factor 2 receptor and insulin-like growth factor binding proteins to identify control mechanisms for insulin-like growth factor 1 receptor phosphorylation.
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Title: The Activation of ERK1/2 and JNK MAPK Signaling by Insulin/IGF-1 Is Responsible for the Development of Colon Cancer with Type 2 Diabetes Mellitus.
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Title: Antitumor and biological investigation of doubly cyclometalated ruthenium(II) organometallics derived from benzimidazolyl derivatives.
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Title: Correlation Between IGFs-Related Proteins Expression and Incidence of Colorectal Cancer in Diabetic Patients and Related Mechanisms.
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Title: Protein kinase C beta II suppresses colorectal cancer by regulating IGF-1 mediated cell survival.
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Journal: Mol Nutr Food Res. 2016 Sep;60(9):1912-23.
Title: Comparison of anti-inflammatory mechanisms of mango (Mangifera Indica L.) and pomegranate (Punica Granatum L.) in a preclinical model of colitis.
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Journal: Anticancer Res. 2016 Apr;36(4):1901-7.
Title: Predictive Value of Growth Factors and Interleukins for Future Liver Remnant Volume and Colorectal Liver Metastasis Volume Growth Following Portal Vein Embolization and Autologous Stem Cell Application.
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Journal: Metabolism. 2016 May;65(5):685-98.
Title: Aerobic and resistance training dependent skeletal muscle plasticity in the colon-26 murine model of cancer cachexia.
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Title: Higher Expression of Proteins in IGF/IR Axes in Colorectal Cancer is Associated with Type 2 Diabetes Mellitus.
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Journal: Oncol Lett. 2016 Jul;12(1):250-256.
Title: Statin induces apoptosis of human colon cancer cells and downregulation of insulin-like growth factor 1 receptor via proapoptotic ERK activation.
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Title: Does IGF-1 play a role in the biology of endometrial cancer?
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Journal: Apoptosis. 2016 Dec;21(12):1398-1407.
Title: Oxymatrine synergistically enhances antitumor activity of oxaliplatin in colon carcinoma through PI3K/AKT/mTOR pathway.
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Journal: Oncotarget. 2016 Nov 15;7(46):75366-75378.
Title: Polarization of macrophages in the tumor microenvironment is influenced by EGFR signaling within colon cancer cells.
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Title: Correlations of insulin-like growth factor I and insulin-like growth factor I receptor with the clinicopathological features and prognosis of patients with colon cancer.
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Journal: Recent Results Cancer Res. 2016;208:199-217.
Title: Obesity Biomarkers, Metabolism and Risk of Cancer: An Epidemiological Perspective.
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Journal: Oncogene. 2017 Feb 9;36(6):797-806.
Title: Overproduction of IGF-2 drives a subset of colorectal cancer cells, which specifically respond to an anti-IGF therapeutic antibody and combination therapies.
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Journal: Pituitary. 2017 Feb;20(1):70-75.
Title: Complications of acromegaly: thyroid and colon.
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Journal: Int J Cancer. 2017 Jan 15;140(2):272-284.
Title: Energy restriction at young age, genetic variants in the insulin-like growth factor pathway and colorectal cancer risk in the Netherlands Cohort Study.
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Title: Dalotuzumab in chemorefractory KRAS exon 2 mutant colorectal cancer: Results from a randomised phase II/III trial.
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Journal: Oncotarget. 2017 Jan 10;8(2):3683-3695.
Title: The role of extracellular vesicles in mediating progression, metastasis and potential treatment of hepatocellular carcinoma.
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Journal: Menopause. 2017 Mar;24(3):288-298.
Title: Bioavailable insulin-like growth factor-I as mediator of racial disparity in obesity-relevant breast and colorectal cancer risk among postmenopausal women.
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Journal: Nutr Cancer. 2017 Jan;69(1):56-63.
Title: Randomized Trial Testing the Effects of Eating Frequency on Two Hormonal Biomarkers of Metabolism and Energy Balance.
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Journal: Exp Ther Med. 2017 Jan;13(1):49-54.
Title: Correlation between microvascular characteristics and the expression of MVD, IGF-1 and STAT3 in the development of colonic polyps carcinogenesis.
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Journal: PLoS One. 2017 Feb 7;12(2):e0171664.
Title: Genome-wide analysis identifies colonic genes differentially associated with serum leptin and insulin concentrations in C57BL/6J mice fed a high-fat diet.
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Journal: Peptides. 2017 May;91:49-57.
Title: Glucagon-like petide-2 acts on colon cancer myofibroblasts to stimulate proliferation, migration and invasion of both myofibroblasts and cancer cells via the IGF pathway.
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Journal: Mol Carcinog. 2017 Sep;56(9):2127-2134.
Title: Circulating insulin-like growth factor-related biomarkers: Correlates and responses to calcium supplementation in colorectal adenoma patients.
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Title: Clinicopathological significance and impact on outcomes of the gene expression levels of IGF-1, IGF-2 and IGF-1R, IGFBP-3 in patients with colorectal cancer: Overexpression of the IGFBP-3 gene is an effective predictor of outcomes in patients with colorec
Author: Yamamoto, Naoto|Oshima, Takashi|Yoshihara, Kazue|Aoyama, Toru|Hayashi, Tsutomu|Yamada, Takanobu|Sato, Tsutomu|Shiozawa, Manabu|Yoshikawa, Takaki|Morinaga, Soichiro|Rino, Yasushi|Kunisaki, Chikara|Tanaka, Katsuaki|Akaike, Makoto|Imada, Toshio|Masuda, Munet
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Title: Z-505 hydrochloride, an orally active ghrelin agonist, attenuates the progression of cancer cachexia via anabolic hormones in Colon 26 tumor-bearing mice.
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Title: Stromal-derived IGF2 promotes colon cancer progression via paracrine and autocrine mechanisms.
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Title: Tumour-Derived Human Growth Hormone As a Therapeutic Target in Oncology.
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Title: Solasodine inhibits human colorectal cancer cells through suppression of the AKT/glycogen synthase kinase-3beta/beta-catenin pathway.
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Title: Simultaneous inhibition of IGF1R and EGFR enhances the efficacy of standard treatment for colorectal cancer by the impairment of DNA repair and the induction of cell death.
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Title: The type I insulin-like growth factor regulates the liver stromal response to metastatic colon carcinoma cells.
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Title: Lack of chemopreventive efficacy of metformin in rodent models of urinary bladder, head and neck, and colon/intestine cancer.
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Title: A transcriptome-based protein network that identifies new therapeutic targets in colorectal cancer.
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Title: Genetic variants and traits related to insulin-like growth factor-I and insulin resistance and their interaction with lifestyles on postmenopausal colorectal cancer risk.
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Journal: Obesity (Silver Spring). 2017 Nov;25 Suppl 2:S95-S101.
Title: The Impact of Diet-Induced Weight Loss on Biomarkers for Colorectal Cancer: An Exploratory Study (INTERCEPT).
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Title: SNPs in the Insulin-Like Growth Factor Gene and Obesity Impact on Colorectal Cancer in Egyptians
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Title: Insulin-like growth factor-1 activates different catalytic subunits p110 of PI3K in a cell-type-dependent manner to induce lipogenesis-dependent epithelial-mesenchymal transition through the regulation of ADAM10 and ADAM17.
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Title: Higher IGFBP3 is associated with increased incidence of colorectal cancer in older men independently of IGF1.
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Title: Radiotherapy-Activated Cancer-Associated Fibroblasts Promote Tumor Progression through Paracrine IGF1R Activation.
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Title: Insulin-like growth factor 1 inhibits autophagy of human colorectal carcinoma drug-resistant cells via the protein kinase B/mammalian target of rapamycin signaling pathway.
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Journal: Oncol Rep. 2018 Mar;39(3):1516-1522.
Title: Fucoidan downregulates insulin-like growth factor-I receptor levels in HT-29 human colon cancer cells.
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Title: Insulin receptor substrate-4 is overexpressed in colorectal cancer and promotes retinoblastoma-cyclin-dependent kinase activation.
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Journal: Obes Res Clin Pract. 2018 May - Jun;12(3):251-259.
Title: The mechanisms linking obesity to colon cancer: An overview.
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Journal: Cancer Biomark. 2018;21(4):883-891.
Title: Expressions of IGF-1, ERK, GLUT4, IRS-1 in metabolic syndrome complicated with colorectal cancer and their associations with the clinical characteristics of CRC.
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Title: Loss of neutrophil polarization in colon carcinoma liver metastases of mice with an inducible, liver-specific IGF-I deficiency.
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Title: IGF1/IGF1R and microRNA let-7e down-regulate each other and modulate proliferation and migration of colorectal cancer cells.
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Title: Myeloid p38alpha signaling promotes intestinal IGF-1 production and inflammation-associated tumorigenesis.
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Title: Activation of insulin receptors and IGF-1 receptors in COLO-205 colon cancer xenografts by insulin and insulin analogue X10 does not enhance growth under normo- or hypoglycaemic conditions.
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Title: MiR-1260b inhibitor enhances the chemosensitivity of colorectal cancer cells to fluorouracil by targeting PDCD4/IGF1.
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Journal: Cancers (Basel). 2018 Sep 25;10(10). pii: cancers10100353.
Title: Destruxin B Suppresses Drug-Resistant Colon Tumorigenesis and Stemness Is Associated with the Upregulation of miR-214 and Downregulation of mTOR/beta-Catenin Pathway.
Author: Wu, Szu-Yuan|Huang, Yan-Jiun|Tzeng, Yew-Min|Huang, Chi-Ying F|Hsiao, Michael|Wu, Alexander T H|Huang, Tse-Hung
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Title: Prevalence of neoplasms in patients with acromegaly - the need for a national registry.
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Title: Cellular polarity modulates drug resistance in primary colorectal cancers via orientation of the multidrug resistance protein ABCB1.
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Title: Meta-analysis of the association of IGFBP3 and IGF1 polymorphisms with susceptibility to colorectal cancer.
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Title: Non-target Genes Regulate miRNAs-Mediated Migration Steering of Colorectal Carcinoma.
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