Primary Site >> Colorectal Cancer

Gene >> IDO1

Journal: Gene. 1991 Sep 15;105(2):221-7.
Title: Cloning and expression of a cDNA encoding mouse indoleamine 2,3-dioxygenase.
Author: Habara-Ohkubo, A|Takikawa, O|Yoshida, R
PMID: 1937018
Journal: Infect Immun. 1993 May;61(5):1810-3.
Title: Establishment of an antitoxoplasma state by stable expression of mouse indoleamine 2,3-dioxygenase.
Author: Habara-Ohkubo, A|Shirahata, T|Takikawa, O|Yoshida, R
PMID: 8478070
Journal: Clin Cancer Res. 2006 Feb 15;12(4):1144-51.
Title: Prognostic value of indoleamine 2,3-dioxygenase expression in colorectal cancer: effect on tumor-infiltrating T cells.
Author: Brandacher, Gerald|Perathoner, Alexander|Ladurner, Ruth|Schneeberger, Stefan|Obrist, Peter|Winkler, Christiana|Werner, Ernst R|Werner-Felmayer, Gabriele|Weiss, Helmut G|Gobel, Georg|Margreiter, Raimund|Konigsrainer, Alfred|Fuchs, Dietmar|Amberger, Albert
PMID: 16489067
Journal: Cancer Immun. 2007 Jun 26;7:10.
Title: Focus on TILs: Prognostic significance of tumor infiltrating lymphocytes in human bladder cancer.
Author: Liakou, Chrysoula I|Narayanan, Sowmita|Ng Tang, Derek|Logothetis, Christopher J|Sharma, Padmanee
PMID: 17591743
Journal: Cytotechnology. 2007 Jun;54(2):107-13.
Title: Transcriptional regulation of indoleamine 2,3-dioxygenase (IDO) by tryptophan and its analogue : Down-regulation of the indoleamine 2,3-dioxygenase (IDO) transcription by tryptophan and its analogue.
Author: Okamoto, Takeaki|Tone, Shigenobu|Kanouchi, Hiroaki|Miyawaki, Chie|Ono, Sayuri|Minatogawa, Yohsuke
PMID: 19003025
Journal: Cancer Immunol Immunother. 2009 Jan;58(1):153-7.
Title: IDO1 and IDO2 are expressed in human tumors: levo- but not dextro-1-methyl tryptophan inhibits tryptophan catabolism.
Author: Lob, Stefan|Konigsrainer, Alfred|Zieker, Derek|Brucher, Bjorn L D M|Rammensee, Hans-Georg|Opelz, Gerhard|Terness, Peter
PMID: 18418598
Journal: Clin Cancer Res. 2009 Jan 15;15(2):641-9.
Title: A novel cancer therapy by skin delivery of indoleamine 2,3-dioxygenase siRNA.
Author: Yen, Meng-Chi|Lin, Chi-Chen|Chen, Yi-Ling|Huang, Shih-Shien|Yang, Huei-Jiun|Chang, Chih-Peng|Lei, Huan-Yao|Lai, Ming-Derg
PMID: 19147770
Journal: J Transl Med. 2009 Aug 20;7:71.
Title: The paradoxical patterns of expression of indoleamine 2,3-dioxygenase in colon cancer.
Author: Gao, Yan-Fang|Peng, Rui-Qing|Li, Jiang|Ding, Ya|Zhang, Xing|Wu, Xiao-Jun|Pan, Zhi-Zhong|Wan, De-Sen|Zeng, Yi-Xin|Zhang, Xiao-Shi
PMID: 19695096
Journal: Mol Cancer Ther. 2010 Feb;9(2):489-98.
Title: Hydroxyamidine inhibitors of indoleamine-2,3-dioxygenase potently suppress systemic tryptophan catabolism and the growth of IDO-expressing tumors.
Author: Koblish, Holly K|Hansbury, Michael J|Bowman, Kevin J|Yang, Gengjie|Neilan, Claire L|Haley, Patrick J|Burn, Timothy C|Waeltz, Paul|Sparks, Richard B|Yue, Eddy W|Combs, Andrew P|Scherle, Peggy A|Vaddi, Kris|Fridman, Jordan S
PMID: 20124451
Journal: Cancer Sci. 2011 Dec;102(12):2214-20.
Title: Skin delivery of short hairpin RNA of indoleamine 2,3 dioxygenase induces antitumor immunity against orthotopic and metastatic liver cancer.
Author: Huang, Tzu-Ting|Yen, Meng-Chi|Lin, Chi-Chen|Weng, Tzu-Yang|Chen, Yi-Ling|Lin, Chiu-Mei|Lai, Ming-Derg
PMID: 21899659
Journal: Br J Cancer. 2012 Jan 3;106(1):141-7.
Title: Clinicopathological significance of indoleamine 2,3-dioxygenase 1 expression in colorectal cancer.
Author: Ferdinande, L|Decaestecker, C|Verset, L|Mathieu, A|Moles Lopez, X|Negulescu, A-M|Van Maerken, T|Salmon, I|Cuvelier, C A|Demetter, P
PMID: 22108515
Journal: Oncol Lett. 2012 Sep;4(3):546-550.
Title: (-)-Epigallocatechin gallate inhibits the expression of indoleamine 2,3-dioxygenase in human colorectal cancer cells.
Author: Ogawa, Kengo|Hara, Takeshi|Shimizu, Masahito|Nagano, Junji|Ohno, Tomohiko|Hoshi, Masato|Ito, Hiroyasu|Tsurumi, Hisashi|Saito, Kuniaki|Seishima, Mitsuru|Moriwaki, Hisataka
PMID: 23741252
Journal: Cancer Sci. 2012 May;103(5):951-8.
Title: Suppression of azoxymethane-induced colonic preneoplastic lesions in rats by 1-methyltryptophan, an inhibitor of indoleamine 2,3-dioxygenase.
Author: Ogawa, Kengo|Hara, Takeshi|Shimizu, Masahito|Ninomiya, Soranobu|Nagano, Junji|Sakai, Hiroyasu|Hoshi, Masato|Ito, Hiroyasu|Tsurumi, Hisashi|Saito, Kuniaki|Seishima, Mitsuru|Tanaka, Takuji|Moriwaki, Hisataka
PMID: 22320717
Journal: Biochem Cell Biol. 2012 Apr;90(2):173-8.
Title: Changes in the levels of thioredoxin and indoleamine-2,3-dioxygenase activity in plasma of patients with colorectal cancer treated with chemotherapy.
Author: Cavia-Saiz, Monica|Muniz, Pilar|De Santiago, Reyes|Herreros-Villanueva, Marta|Garcia-Giron, Carlos|Lopez, Ana Sofia|Coma-Del Corral, Maria Jesus
PMID: 22257103
Journal: Curr Opin Gastroenterol. 2013 Mar;29(2):146-52.
Title: Indoleamine 2,3 dioxygenase in intestinal disease.
Author: Ciorba, Matthew A
PMID: 23283180
Journal: Gastroenterology. 2013 Aug;145(2):416-25.e1-4.
Title: IDO1 metabolites activate beta-catenin signaling to promote cancer cell proliferation and colon tumorigenesis in mice.
Author: Thaker, Ameet I|Rao, M Suprada|Bishnupuri, Kumar S|Kerr, Thomas A|Foster, Lynne|Marinshaw, Jeffrey M|Newberry, Rodney D|Stenson, William F|Ciorba, Matthew A
PMID: 23669411
Journal: Mol Biol Rep. 2014;41(4):2275-9.
Title: The role of plasma IDO activity as a diagnostic marker of patients with colorectal cancer.
Author: Cavia-Saiz, M|Muniz Rodriguez, P|Llorente Ayala, B|Garcia-Gonzalez, M|Coma-Del Corral, M J|Garcia Giron, C
PMID: 24435977
Journal: Oncotarget. 2015 Oct 20;6(32):32561-74.
Title: An integrative approach for the identification of prognostic and predictive biomarkers in rectal cancer.
Author: Agostini, Marco|Janssen, Klaus-Peter|Kim, Il-Jin|D'Angelo, Edoardo|Pizzini, Silvia|Zangrando, Andrea|Zanon, Carlo|Pastrello, Chiara|Maretto, Isacco|Digito, Maura|Bedin, Chiara|Jurisica, Igor|Rizzolio, Flavio|Giordano, Antonio|Bortoluzzi, Stefania|Nitti, D
PMID: 26359356
Journal: Am J Cancer Res. 2015 Jun 15;5(7):2222-8. eCollection 2015.
Title: The treatment of mouse colorectal cancer by oral delivery tumor-targeting Salmonella.
Author: Wang, Wei-Kuang|Lu, Meng-Fan|Kuan, Yu-Diao|Lee, Che-Hsin
PMID: 26328252
Journal: Cancer Sci. 2015 Aug;106(8):1008-15.
Title: Inhibition of indoleamine 2,3-dioxygenase 1 expression alters immune response in colon tumor microenvironment in mice.
Author: Takamatsu, Manabu|Hirata, Akihiro|Ohtaki, Hirofumi|Hoshi, Masato|Ando, Tatsuya|Ito, Hiroyasu|Hatano, Yuichiro|Tomita, Hiroyuki|Kuno, Toshiya|Saito, Kuniaki|Seishima, Mitsuru|Hara, Akira
PMID: 26033215
Journal: PLoS One. 2015 Apr 16;10(4):e0122046.
Title: Accumulation of an endogenous tryptophan-derived metabolite in colorectal and breast cancers.
Author: Puccetti, Paolo|Fallarino, Francesca|Italiano, Antoine|Soubeyran, Isabelle|MacGrogan, Gaetan|Debled, Marc|Velasco, Valerie|Bodet, Dominique|Eimer, Sandrine|Veldhoen, Marc|Prendergast, Georges C|Platten, Michael|Bessede, Alban|Guillemin, Gilles J
PMID: 25881064
Journal: Cancer Discov. 2015 Jan;5(1):16-8.
Title: The microsatellite instable subset of colorectal cancer is a particularly good candidate for checkpoint blockade immunotherapy.
Author: Xiao, Yanping|Freeman, Gordon J
PMID: 25583798
Journal: Biochem J. 2015 Jul 15;469(2):267-78.
Title: Slc5a8, a Na+-coupled high-affinity transporter for short-chain fatty acids, is a conditional tumour suppressor in colon that protects against colitis and colon cancer under low-fibre dietary conditions.
Author: Gurav, Ashish|Sivaprakasam, Sathish|Bhutia, Yangzom D|Boettger, Thomas|Singh, Nagendra|Ganapathy, Vadivel
PMID: 25984582
Journal: Transl Res. 2016 Jan;167(1):67-79.
Title: Therapeutic targeting of inflammation and tryptophan metabolism in colon and gastrointestinal cancer.
Author: Santhanam, Srikanth|Alvarado, David M|Ciorba, Matthew A
PMID: 26297050
Journal: Mod Pathol. 2016 May;29(5):528-41.
Title: Medullary carcinoma of the colon: a distinct morphology reveals a distinctive immunoregulatory microenvironment.
Author: Friedman, Kenneth|Brodsky, Alexander S|Lu, Shaolei|Wood, Stephanie|Gill, Anthony J|Lombardo, Kara|Yang, Dongfang|Resnick, Murray B
PMID: 26965581
Journal: J Cancer Res Clin Oncol. 2016 Aug;142(8):1775-80.
Title: Prognostic relevance of genetic variants involved in immune checkpoints in patients with colorectal cancer.
Author: Yoon, Shinkyo|Kang, Byung Woog|Park, Su Yeon|Kim, Hye Jin|Park, Jun Seok|Choi, Gyu Seog|Kim, Jong Gwang
PMID: 27339628
Journal: J Am Chem Soc. 2016 Sep 28;138(38):12502-10.
Title: Chlorin-Based Nanoscale Metal-Organic Framework Systemically Rejects Colorectal Cancers via Synergistic Photodynamic Therapy and Checkpoint Blockade Immunotherapy.
Author: Lu, Kuangda|He, Chunbai|Guo, Nining|Chan, Christina|Ni, Kaiyuan|Weichselbaum, Ralph R|Lin, Wenbin
PMID: 27575718
Journal: Dis Markers. 2016;2016:8169724.
Title: Expression Pattern and Clinicopathological Relevance of the Indoleamine 2,3-Dioxygenase 1/Tryptophan 2,3-Dioxygenase Protein in Colorectal Cancer.
Author: Chen, I-Chien|Lee, Kuen-Haur|Hsu, Ying-Hua|Wang, Wei-Ran|Chen, Chuan-Mu|Cheng, Ya-Wen
PMID: 27578919
Journal: Brain Behav Immun. 2017 May;62:78-86.
Title: Epinephrine promotes COX-2-dependent immune suppression in myeloid cells and cancer tissues.
Author: Muthuswamy, Ravikumar|Okada, Nana J|Jenkins, Frank J|McGuire, Kandace|McAuliffe, Priscilla F|Zeh, Herbert J|Bartlett, David L|Wallace, Callen|Watkins, Simon|Henning, Jill D|Bovbjerg, Dana H|Kalinski, Pawel
PMID: 28212885
Journal: Mol Clin Oncol. 2017 May;6(5):701-704.
Title: Expression of CXCR-4 and IDO in human colorectal cancer: An immunohistochemical approach.
Author: Ogawa, Masaichi|Watanabe, Michiaki|Hasegawa, Takuo|Ichihara, Kohei|Yoshida, Kazuhiko|Yanaga, Katsuhiko
PMID: 28515923
Journal: Cell Cycle. 2017 Jul 3;16(13):1295-1301.
Title: Long noncoding RNA lnc-sox5 modulates CRC tumorigenesis by unbalancing tumor microenvironment.
Author: Wu, Kaiming|Zhao, Zhenxian|Liu, Kuanzhi|Zhang, Jian|Li, Guanghua|Wang, Liang
PMID: 28632999
Journal: Pathology. 2018 Oct;50(6):607-612.
Title: Immunological environment in colorectal cancer: a computer-aided morphometric study of whole slide digital images derived from tissue microarray.
Author: Eyraud, Daniel|Granger, Benjamin|Bardier, Armelle|Loncar, Yann|Gottrand, GaElle|Le Naour, Gilles|Siksik, Jean-Michel|Vaillant, Jean-Christophe|Klatzmann, David|Puybasset, Louis|Charlotte, Frederic|Augustin, Jeremy
PMID: 30166125
Journal: Biol Pharm Bull. 2018;41(8):1243-1250.
Title: Celastrol Suppresses Tryptophan Catabolism in Human Colon Cancer Cells as Revealed by Metabolic Profiling and Targeted Metabolite Analysis.
Author: Qi, Yunpeng|Wang, Renping|Zhao, Liang|Lv, Lei|Zhou, Fan|Zhang, Tian|Lu, Feng|Yan, Hongli|Duan, Gengli
PMID: 30068874
Journal: Adv Mater. 2018 Sep;30(38):e1803001.
Title: Binary Cooperative Prodrug Nanoparticles Improve Immunotherapy by Synergistically Modulating Immune Tumor Microenvironment.
Author: Feng, Bing|Zhou, Fangyuan|Hou, Bo|Wang, Dangge|Wang, Tingting|Fu, Yuanlei|Ma, Yuting|Yu, Haijun|Li, Yaping
PMID: 30063262
Journal: Nat Biotechnol. 2018 Sep;36(8):758-764.
Title: Reversal of indoleamine 2,3-dioxygenase-mediated cancer immune suppression by systemic kynurenine depletion with a therapeutic enzyme.
Author: Triplett, Todd A|Garrison, Kendra C|Marshall, Nicholas|Donkor, Moses|Blazeck, John|Lamb, Candice|Qerqez, Ahlam|Dekker, Joseph D|Tanno, Yuri|Lu, Wei-Cheng|Karamitros, Christos S|Ford, Kyle|Tan, Bing|Zhang, Xiaoyan M|McGovern, Karen|Coma, Silvia|Kumada, Yoi
PMID: 30010674
Journal: Oncotarget. 2018 May 18;9(38):25216-25224.
Title: Peritumoral endothelial indoleamine 2, 3-dioxygenase expression is an early independent marker of disease relapse in colorectal cancer and is influenced by DNA mismatch repair profile.
Author: Meireson, Annabel|Chevolet, Ines|Hulstaert, Eva|Ferdinande, Liesbeth|Ost, Piet|Geboes, Karen|De Man, Marc|Van de Putte, Dirk|Verset, Laurine|Kruse, Vibeke|Demetter, Pieter|Brochez, Lieve
PMID: 29861865
Journal: World J Gastroenterol. 2018 May 28;24(20):2181-2190.
Title: Indoleamine-2,3-dioxygenase 1/cyclooxygenase 2 expression prediction for adverse prognosis in colorectal cancer.
Author: Ma, Wen-Juan|Wang, Xing|Yan, Wen-Ting|Zhou, Zhong-Guo|Pan, Zhi-Zhong|Chen, Gong|Zhang, Rong-Xin
PMID: 29853736
Journal: Ann Surg Oncol. 2018 Aug;25(8):2323-2331.
Title: Cytolytic Activity Score to Assess Anticancer Immunity in Colorectal Cancer.
Author: Narayanan, Sumana|Kawaguchi, Tsutomu|Yan, Li|Peng, Xuan|Qi, Qianya|Takabe, Kazuaki
PMID: 29770915
Journal: J Hematol Oncol. 2018 Apr 23;11(1):58.
Title: miR-153 suppresses IDO1 expression and enhances CAR T cell immunotherapy.
Author: Huang, Qian|Xia, Jiajia|Wang, Lei|Wang, Xu|Ma, Xiaodong|Deng, Qipan|Lu, Yong|Kumar, Munish|Zhou, Zhiyuan|Li, Ling|Zeng, Zhaoyang|Young, Ken H|Yi, Qing|Zhang, Mingzhi|Li, Yong
PMID: 29685162
Journal: Int J Cancer. 2018 Sep 15;143(6):1516-1529.
Title: 1-L-MT, an IDO inhibitor, prevented colitis-associated cancer by inducing CDC20 inhibition-mediated mitotic death of colon cancer cells.
Author: Liu, Xiuting|Zhou, Wei|Zhang, Xin|Ding, Yang|Du, Qianming|Hu, Rong
PMID: 29607498
Journal: J Cancer Res Clin Oncol. 2018 Jun;144(6):1005-1014.
Title: CD274, LAG3, and IDO1 expressions in tumor-infiltrating immune cells as prognostic biomarker for patients with MSI-high colon cancer.
Author: Lee, Soo Jung|Jun, Sun-Young|Lee, In Hee|Kang, Byung Woog|Park, Su Yeon|Kim, Hye Jin|Park, Jun Seok|Choi, Gyu-Seog|Yoon, Ghilsuk|Kim, Jong Gwang
PMID: 29520442
Journal: Cell Death Dis. 2018 Mar 2;9(3):355.
Title: Indoleamine 2,3-dioxygenase expression regulates the survival and proliferation of Fusobacterium nucleatum in THP-1-derived macrophages.
Author: Xue, Ying|Xiao, Han|Guo, Songhe|Xu, Banglao|Liao, Yuehua|Wu, Yixian|Zhang, Ge
PMID: 29500439