Primary Site >> Colorectal Cancer
Gene >> IDO1
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Ref: Cloning and expression of a cDNA encoding mouse indoleamine 2,3-dioxygenase. PMID: 1937018 |
Ref: Establishment of an antitoxoplasma state by stable expression of mouse indoleamine 2,3-dioxygenase. PMID: 8478070 |
Ref: Prognostic value of indoleamine 2,3-dioxygenase expression in colorectal cancer: effect on tumor-infiltrating T cells. PMID: 16489067 |
Ref: Focus on TILs: Prognostic significance of tumor infiltrating lymphocytes in human bladder cancer. PMID: 17591743 Ref: Transcriptional regulation of indoleamine 2,3-dioxygenase (IDO) by tryptophan and its analogue : Down-regulation of the indoleamine 2,3-dioxygenase (IDO) transcription by tryptophan and its analogue. PMID: 19003025 |
Ref: IDO1 and IDO2 are expressed in human tumors: levo- but not dextro-1-methyl tryptophan inhibits tryptophan catabolism. PMID: 18418598 Ref: A novel cancer therapy by skin delivery of indoleamine 2,3-dioxygenase siRNA. PMID: 19147770 Ref: The paradoxical patterns of expression of indoleamine 2,3-dioxygenase in colon cancer. PMID: 19695096 |
Ref: Hydroxyamidine inhibitors of indoleamine-2,3-dioxygenase potently suppress systemic tryptophan catabolism and the growth of IDO-expressing tumors. PMID: 20124451 |
Ref: Skin delivery of short hairpin RNA of indoleamine 2,3 dioxygenase induces antitumor immunity against orthotopic and metastatic liver cancer. PMID: 21899659 |
Ref: Clinicopathological significance of indoleamine 2,3-dioxygenase 1 expression in colorectal cancer. PMID: 22108515 Ref: Changes in the levels of thioredoxin and indoleamine-2,3-dioxygenase activity in plasma of patients with colorectal cancer treated with chemotherapy. PMID: 22257103 Ref: Suppression of azoxymethane-induced colonic preneoplastic lesions in rats by 1-methyltryptophan, an inhibitor of indoleamine 2,3-dioxygenase. PMID: 22320717 Ref: (-)-Epigallocatechin gallate inhibits the expression of indoleamine 2,3-dioxygenase in human colorectal cancer cells. PMID: 23741252 |
Ref: Indoleamine 2,3 dioxygenase in intestinal disease. PMID: 23283180 Ref: IDO1 metabolites activate beta-catenin signaling to promote cancer cell proliferation and colon tumorigenesis in mice. PMID: 23669411 |
Ref: The role of plasma IDO activity as a diagnostic marker of patients with colorectal cancer. PMID: 24435977 |
Ref: The microsatellite instable subset of colorectal cancer is a particularly good candidate for checkpoint blockade immunotherapy. PMID: 25583798 Ref: Accumulation of an endogenous tryptophan-derived metabolite in colorectal and breast cancers. PMID: 25881064 Ref: Slc5a8, a Na+-coupled high-affinity transporter for short-chain fatty acids, is a conditional tumour suppressor in colon that protects against colitis and colon cancer under low-fibre dietary conditions. PMID: 25984582 Ref: Inhibition of indoleamine 2,3-dioxygenase 1 expression alters immune response in colon tumor microenvironment in mice. PMID: 26033215 Ref: The treatment of mouse colorectal cancer by oral delivery tumor-targeting Salmonella. PMID: 26328252 Ref: An integrative approach for the identification of prognostic and predictive biomarkers in rectal cancer. PMID: 26359356 |
Ref: Therapeutic targeting of inflammation and tryptophan metabolism in colon and gastrointestinal cancer. PMID: 26297050 Ref: Medullary carcinoma of the colon: a distinct morphology reveals a distinctive immunoregulatory microenvironment. PMID: 26965581 Ref: Prognostic relevance of genetic variants involved in immune checkpoints in patients with colorectal cancer. PMID: 27339628 Ref: Chlorin-Based Nanoscale Metal-Organic Framework Systemically Rejects Colorectal Cancers via Synergistic Photodynamic Therapy and Checkpoint Blockade Immunotherapy. PMID: 27575718 Ref: Expression Pattern and Clinicopathological Relevance of the Indoleamine 2,3-Dioxygenase 1/Tryptophan 2,3-Dioxygenase Protein in Colorectal Cancer. PMID: 27578919 |
Ref: Epinephrine promotes COX-2-dependent immune suppression in myeloid cells and cancer tissues. PMID: 28212885 Ref: Expression of CXCR-4 and IDO in human colorectal cancer: An immunohistochemical approach. PMID: 28515923 Ref: Long noncoding RNA lnc-sox5 modulates CRC tumorigenesis by unbalancing tumor microenvironment. PMID: 28632999 |
Ref: Indoleamine 2,3-dioxygenase expression regulates the survival and proliferation of Fusobacterium nucleatum in THP-1-derived macrophages. PMID: 29500439 Ref: CD274, LAG3, and IDO1 expressions in tumor-infiltrating immune cells as prognostic biomarker for patients with MSI-high colon cancer. PMID: 29520442 Ref: 1-L-MT, an IDO inhibitor, prevented colitis-associated cancer by inducing CDC20 inhibition-mediated mitotic death of colon cancer cells. PMID: 29607498 Ref: miR-153 suppresses IDO1 expression and enhances CAR T cell immunotherapy. PMID: 29685162 Ref: Cytolytic Activity Score to Assess Anticancer Immunity in Colorectal Cancer. PMID: 29770915 Ref: Indoleamine-2,3-dioxygenase 1/cyclooxygenase 2 expression prediction for adverse prognosis in colorectal cancer. PMID: 29853736 Ref: Peritumoral endothelial indoleamine 2, 3-dioxygenase expression is an early independent marker of disease relapse in colorectal cancer and is influenced by DNA mismatch repair profile. PMID: 29861865 Ref: Reversal of indoleamine 2,3-dioxygenase-mediated cancer immune suppression by systemic kynurenine depletion with a therapeutic enzyme. PMID: 30010674 Ref: Binary Cooperative Prodrug Nanoparticles Improve Immunotherapy by Synergistically Modulating Immune Tumor Microenvironment. PMID: 30063262 Ref: Celastrol Suppresses Tryptophan Catabolism in Human Colon Cancer Cells as Revealed by Metabolic Profiling and Targeted Metabolite Analysis. PMID: 30068874 Ref: Immunological environment in colorectal cancer: a computer-aided morphometric study of whole slide digital images derived from tissue microarray. PMID: 30166125 |