Primary Site >> Liver Cancer

Gene >> IDH1

Journal: Oncogene. 2013 Oct 10;32(41):4861-70.
Title: Intrahepatic cholangiocarcinoma: pathogenesis and rationale for molecular therapies.
Author: Sia, D|Tovar, V|Moeini, A|Llovet, J M
PMID: 23318457
Journal: Med Sci Monit. 2014 Feb 14;20:247-54.
Title: IDH1 p.R132 mutations may not be actively involved in the carcinogenesis of hepatocellular carcinoma.
Author: Lu, Jun|Xu, Ling|Zou, Yang|Yang, Run-Xiang|Fan, Yu|Zhang, Wen|Yu, Dandan|Yao, Yong-Gang
PMID: 24531386
Journal: J Hepatobiliary Pancreat Sci. 2014 Jun;21(6):380-7.
Title: Genomic and transcriptional alterations of cholangiocarcinoma.
Author: Ito, Takeshi|Sakurai-Yageta, Mika|Goto, Akiteru|Pairojkul, Chawalit|Yongvanit, Puangrat|Murakami, Yoshinori
PMID: 24532422
Journal: Oncologist. 2014 Mar;19(3):235-42.
Title: New routes to targeted therapy of intrahepatic cholangiocarcinomas revealed by next-generation sequencing.
Author: Ross, Jeffrey S|Wang, Kai|Gay, Laurie|Al-Rohil, Rami|Rand, Janne V|Jones, David M|Lee, Hwa J|Sheehan, Christine E|Otto, Geoff A|Palmer, Gary|Yelensky, Roman|Lipson, Doron|Morosini, Deborah|Hawryluk, Matthew|Catenacci, Daniel V T|Miller, Vincent A|Churi, C
PMID: 24563076
Journal: Nature. 2014 Sep 4;513(7516):110-4.
Title: Mutant IDH inhibits HNF-4alpha to block hepatocyte differentiation and promote biliary cancer.
Author: Saha, Supriya K|Parachoniak, Christine A|Ghanta, Krishna S|Fitamant, Julien|Ross, Kenneth N|Najem, Mortada S|Gurumurthy, Sushma|Akbay, Esra A|Sia, Daniela|Cornella, Helena|Miltiadous, Oriana|Walesky, Chad|Deshpande, Vikram|Zhu, Andrew X|Hezel, Aram F|Yen,
PMID: 25043045
Journal: Genome Biol. 2014 Aug 26;15(8):436.
Title: Diverse modes of genomic alteration in hepatocellular carcinoma.
Author: Jhunjhunwala, Suchit|Jiang, Zhaoshi|Stawiski, Eric W|Gnad, Florian|Liu, Jinfeng|Mayba, Oleg|Du, Pan|Diao, Jingyu|Johnson, Stephanie|Wong, Kwong-Fai|Gao, Zhibo|Li, Yingrui|Wu, Thomas D|Kapadia, Sharookh B|Modrusan, Zora|French, Dorothy M|Luk, John M|Seshag
PMID: 25159915
Journal: Med Oncol. 2014 Nov;31(11):278.
Title: Genetic variations in IDH gene as prognosis predictors in TACE-treated hepatocellular carcinoma patients.
Author: Zhang, Huiqing|Guo, Xu|Dai, Jingyao|Wu, Yousheng|Ge, Naijian|Yang, Yefa|Ji, Jiansong|Zhang, Hongxin
PMID: 25355558
Journal: Nat Commun. 2015 Jan 22;6:6087.
Title: Massive parallel sequencing uncovers actionable FGFR2-PPHLN1 fusion and ARAF mutations in intrahepatic cholangiocarcinoma.
Author: Sia, Daniela|Losic, Bojan|Moeini, Agrin|Cabellos, Laia|Hao, Ke|Revill, Kate|Bonal, Dennis|Miltiadous, Oriana|Zhang, Zhongyang|Hoshida, Yujin|Cornella, Helena|Castillo-Martin, Mireia|Pinyol, Roser|Kasai, Yumi|Roayaie, Sasan|Thung, Swan N|Fuster, Josep|Schw
PMID: 25608663
Journal: Clin Epigenetics. 2015 Sep 11;7:98.
Title: Induction of active demethylation and 5hmC formation by 5-azacytidine is TET2 dependent and suggests new treatment strategies against hepatocellular carcinoma.
Author: Sajadian, Sahar Olsadat|Ehnert, Sabrina|Vakilian, Haghighat|Koutsouraki, Eirini|Damm, Georg|Seehofer, Daniel|Thasler, Wolfgang|Dooley, Steven|Baharvand, Hossein|Sipos, Bence|Nussler, Andreas K
PMID: 26366235
Journal: Oncotarget. 2016 Jul 19;7(29):46750-46767.
Title: The landscape of targeted therapies for cholangiocarcinoma: current status and emerging targets.
Author: Chong, Dawn Q|Zhu, Andrew X
PMID: 27102149
Journal: Histopathology. 2017 Feb;70(3):423-434.
Title: Mutational landscape of combined hepatocellular carcinoma and cholangiocarcinoma, and its clinicopathological significance.
Author: Sasaki, Motoko|Sato, Yasunori|Nakanuma, Yasuni
PMID: 27634656
Journal: BMC Genomics. 2017 Aug 22;18(1):641.
Title: Proteomic and transcriptomic studies of HBV-associated liver fibrosis of an AAV-HBV-infected mouse model.
Author: Kan, Fangming|Ye, Lei|Yan, Tao|Cao, Jiaqi|Zheng, Jianhua|Li, Wuping
PMID: 28830339
Journal: Free Radic Biol Med. 2017 Nov;112:149-161.
Title: Control of the NADPH supply for oxidative stress handling in cancer cells.
Author: Moreno-Sanchez, Rafael|Gallardo-Perez, Juan Carlos|Rodriguez-Enriquez, Sara|Saavedra, Emma|Marin-Hernandez, Alvaro
PMID: 28739529
Journal: Cell. 2017 Jun 15;169(7):1327-1341.e23.
Title: Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma.
Author:
PMID: 28622513
Journal: World J Surg Oncol. 2017 Apr 12;15(1):82.
Title: IDH1 R132C mutation is detected in clear cell hepatocellular carcinoma by pyrosequencing.
Author: Lee, Jung Hee|Shin, Dong Hoon|Park, Won Young|Shin, Nari|Kim, Ahrong|Lee, Hyun Jung|Kim, Young Keum|Choi, Kyung Un|Kim, Jee Yeon|Yang, Young Il|Lee, Chang Hun|Sol, Mee Young
PMID: 28403884
Journal: Biochim Biophys Acta Mol Basis Dis. 2018 Jun;1864(6 Pt B):2360-2368.
Title: Whole-exome mutational and transcriptional landscapes of combined hepatocellular cholangiocarcinoma and intrahepatic cholangiocarcinoma reveal molecular diversity.
Author: Liu, Zhen-Hao|Lian, Bao-Feng|Dong, Qiong-Zhu|Sun, Han|Wei, Jin-Wang|Sheng, Yuan-Yuan|Li, Wei|Li, Yi-Xue|Xie, Lu|Liu, Lei|Qin, Lun-Xiu
PMID: 29408647
Journal: Future Oncol. 2018 Mar;14(6):553-566.
Title: Novel targeted therapy strategies for biliary tract cancers and hepatocellular carcinoma.
Author: DeLeon, Thomas T|Ahn, Daniel H|Bogenberger, James M|Anastasiadis, Panos Z|Arora, Mansi|Ramanathan, Ramesh K|Aqel, Bashar A|Vasmatzis, George|Truty, Mark J|Oklu, Rahmi|Bekaii-Saab, Tanios S|Borad, Mitesh J
PMID: 29460642
Journal: Biochim Biophys Acta Bioenerg. 2018 Jul 24. pii: S0005-2728(18)30219-6.
Title: Control of the NADPH supply and GSH recycling for oxidative stress management in hepatoma and liver mitochondria.
Author: Moreno-Sanchez, Rafael|Marin-Hernandez, Alvaro|Gallardo-Perez, Juan Carlos|Vazquez, Citlali|Rodriguez-Enriquez, Sara|Saavedra, Emma
PMID: 30053395
Journal: Front Genet. 2018 Aug 15;9:309.
Title: Emergence of Intrahepatic Cholangiocarcinoma: How High-Throughput Technologies Expedite the Solutions for a Rare Cancer Type.
Author: Shiao, Meng-Shin|Chiablaem, Khajeelak|Charoensawan, Varodom|Ngamphaiboon, Nuttapong|Jinawath, Natini
PMID: 30158952
Journal: Clin Cancer Res. 2018 Oct 29. pii: 1078-0432.CCR-18-2293.
Title: Prospective Genotyping of Hepatocellular Carcinoma: Clinical Implications of Next Generation Sequencing for Matching Patients to Targeted and Immune Therapies.
Author: Harding, James J|Nandakumar, Subhiksha|Armenia, Joshua|Khalil, Danny N|Albano, Melanie|Ly, Michele|Shia, Jinru|Hechtman, Jaclyn F|Kundra, Ritika|El Dika, Imane|Do, Richard K|Sun, Yichao|Kingham, T Peter|D'Angelica, Michael I|Berger, Michael F|Hyman, David
PMID: 30373752