Primary Site >> Liver Cancer
Gene >> IDH1
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Ref: Intrahepatic cholangiocarcinoma: pathogenesis and rationale for molecular therapies. PMID: 23318457 |
Ref: IDH1 p.R132 mutations may not be actively involved in the carcinogenesis of hepatocellular carcinoma. PMID: 24531386 Ref: Genomic and transcriptional alterations of cholangiocarcinoma. PMID: 24532422 Ref: New routes to targeted therapy of intrahepatic cholangiocarcinomas revealed by next-generation sequencing. PMID: 24563076 Ref: Mutant IDH inhibits HNF-4alpha to block hepatocyte differentiation and promote biliary cancer. PMID: 25043045 Ref: Diverse modes of genomic alteration in hepatocellular carcinoma. PMID: 25159915 Ref: Genetic variations in IDH gene as prognosis predictors in TACE-treated hepatocellular carcinoma patients. PMID: 25355558 |
Ref: Massive parallel sequencing uncovers actionable FGFR2-PPHLN1 fusion and ARAF mutations in intrahepatic cholangiocarcinoma. PMID: 25608663 Ref: Induction of active demethylation and 5hmC formation by 5-azacytidine is TET2 dependent and suggests new treatment strategies against hepatocellular carcinoma. PMID: 26366235 |
Ref: The landscape of targeted therapies for cholangiocarcinoma: current status and emerging targets. PMID: 27102149 |
Ref: Mutational landscape of combined hepatocellular carcinoma and cholangiocarcinoma, and its clinicopathological significance. PMID: 27634656 Ref: IDH1 R132C mutation is detected in clear cell hepatocellular carcinoma by pyrosequencing. PMID: 28403884 Ref: Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma. PMID: 28622513 Ref: Control of the NADPH supply for oxidative stress handling in cancer cells. PMID: 28739529 Ref: Proteomic and transcriptomic studies of HBV-associated liver fibrosis of an AAV-HBV-infected mouse model. PMID: 28830339 |
Ref: Whole-exome mutational and transcriptional landscapes of combined hepatocellular cholangiocarcinoma and intrahepatic cholangiocarcinoma reveal molecular diversity. PMID: 29408647 Ref: Novel targeted therapy strategies for biliary tract cancers and hepatocellular carcinoma. PMID: 29460642 Ref: Control of the NADPH supply and GSH recycling for oxidative stress management in hepatoma and liver mitochondria. PMID: 30053395 Ref: Emergence of Intrahepatic Cholangiocarcinoma: How High-Throughput Technologies Expedite the Solutions for a Rare Cancer Type. PMID: 30158952 Ref: Prospective Genotyping of Hepatocellular Carcinoma: Clinical Implications of Next Generation Sequencing for Matching Patients to Targeted and Immune Therapies. PMID: 30373752 |