Primary Site >> Colorectal Cancer

Gene >> IDH1

Journal: Clin Chem. 2012 Mar;58(3):580-9.
Title: COLD-PCR enrichment of rare cancer mutations prior to targeted amplicon resequencing.
Author: Milbury, Coren A|Correll, Mick|Quackenbush, John|Rubio, Renee|Makrigiorgos, G Mike
PMID: 22194627
Journal: Clin Cancer Res. 2012 Oct 15;18(20):5537-45.
Title: Targeting cancer metabolism.
Author: Teicher, Beverly A|Linehan, W Marston|Helman, Lee J
PMID: 23071355
Journal: Oncogene. 2012 May 10;31(19):2491-8.
Title: Identification of additional IDH mutations associated with oncometabolite R(-)-2-hydroxyglutarate production.
Author: Ward, P S|Cross, J R|Lu, C|Weigert, O|Abel-Wahab, O|Levine, R L|Weinstock, D M|Sharp, K A|Thompson, C B
PMID: 21996744
Journal: Cancer Res. 2013 Jan 15;73(2):496-501.
Title: Disruption of wild-type IDH1 suppresses D-2-hydroxyglutarate production in IDH1-mutated gliomas.
Author: Jin, Genglin|Reitman, Zachary J|Duncan, Christopher G|Spasojevic, Ivan|Gooden, David M|Rasheed, B Ahmed|Yang, Rui|Lopez, Giselle Y|He, Yiping|McLendon, Roger E|Bigner, Darell D|Yan, Hai
PMID: 23204232
Journal: Cancer Res. 2013 Oct 1;73(19):5858-68.
Title: The CpG island methylator phenotype: what's in a name?
Author: Hughes, Laura A E|Melotte, Veerle|de Schrijver, Joachim|de Maat, Michiel|Smit, Vincent T H B M|Bovee, Judith V M G|French, Pim J|van den Brandt, Piet A|Schouten, Leo J|de Meyer, Tim|van Criekinge, Wim|Ahuja, Nita|Herman, James G|Weijenberg, Matty P|van En
PMID: 23801749
Journal: Gene. 2014 Aug 10;546(2):263-70.
Title: Mutation and expression analysis of the IDH1, IDH2, DNMT3A, and MYD88 genes in colorectal cancer.
Author: Li, Wen-Liang|Xiao, Mei-Sheng|Zhang, Deng-Feng|Yu, Dandan|Yang, Run-Xiang|Li, Xiao-Yan|Yao, Yong-Gang
PMID: 24887488
Journal: Epigenetics. 2014 Nov;9(11):1454-60.
Title: Isocitrate dehydrogenase 1 R132C mutation occurs exclusively in microsatellite stable colorectal cancers with the CpG island methylator phenotype.
Author: Whitehall, V L J|Dumenil, T D|McKeone, D M|Bond, C E|Bettington, M L|Buttenshaw, R L|Bowdler, L|Montgomery, G W|Wockner, L F|Leggett, B A
PMID: 25496513
Journal: Int J Oncol. 2015 Mar;46(3):1181-91.
Title: Mathematical analysis predicts imbalanced IDH1/2 expression associates with 2-HG-inactivating beta-oxygenation pathway in colorectal cancer.
Author: Koseki, Jun|Colvin, Hugh|Fukusumi, Takahito|Nishida, Naohiro|Konno, Masamitsu|Kawamoto, Koichi|Tsunekuni, Kenta|Matsui, Hidetoshi|Doki, Yuichiro|Mori, Masaki|Ishii, Hideshi
PMID: 25586680
Journal: Hum Pathol. 2015 Apr;46(4):507-13.
Title: Novel molecular insights from routine genotyping of colorectal carcinomas.
Author: Stachler, Matthew D|Rinehart, Elizabeth|Lindeman, Neal|Odze, Robert|Srivastava, Amitabh
PMID: 25683705
Journal: Cancer Genet. 2015 Sep;208(9):441-7.
Title: Diagnostic yield of targeted next generation sequencing in various cancer types: an information-theoretic approach.
Author: Hagemann, Ian S|O'Neill, Patrick K|Erill, Ivan|Pfeifer, John D
PMID: 26227479
Journal: Cancer Med. 2015 Nov;4(11):1730-41.
Title: Metformin prevents DMH-induced colorectal cancer in diabetic rats by reversing the warburg effect.
Author: Jia, Yanglei|Ma, Zengyi|Liu, Xiaofei|Zhou, Wenjing|He, Shan|Xu, Xia|Ren, Guijie|Xu, Gang|Tian, Keli
PMID: 26376762
Journal: Cancer Metab. 2015 Dec 1;3:13.
Title: Evidence that 2-hydroxyglutarate is not readily metabolized in colorectal carcinoma cells.
Author: Gelman, Susan J|Mahieu, Nathaniel G|Cho, Kevin|Llufrio, Elizabeth M|Wencewicz, Timothy A|Patti, Gary J
PMID: 26629338
Journal: Dig Liver Dis. 2016 Jun;48(6):681-3.
Title: Absence of IDH mutation in colorectal cancers with microsatellite instability.
Author: Tougeron, David|Guilloteau, Karline|Karayan-Tapon, Lucie
PMID: 26987944
Journal: Curr Oncol. 2016 Dec;23(6):e571-e575.
Title: Personalized oncogenomics in the management of gastrointestinal carcinomas-early experiences from a pilot study.
Author: Sheffield, B S|Tessier-Cloutier, B|Li-Chang, H|Shen, Y|Pleasance, E|Kasaian, K|Li, Y|Jones, S J M|Lim, H J|Renouf, D J|Huntsman, D G|Yip, S|Laskin, J|Marra, M|Schaeffer, D F
PMID: 28050146
Journal: Sci Rep. 2016 Nov 8;6:36289.
Title: Oncometabolite D-2-Hydroxyglurate Directly Induces Epithelial-Mesenchymal Transition and is Associated with Distant Metastasis in Colorectal Cancer.
Author: Colvin, Hugh|Nishida, Naohiro|Konno, Masamitsu|Haraguchi, Naotsugu|Takahashi, Hidekazu|Nishimura, Junichi|Hata, Taishi|Kawamoto, Koichi|Asai, Ayumu|Tsunekuni, Kenta|Koseki, Jun|Mizushima, Tsunekazu|Satoh, Taroh|Doki, Yuichiro|Mori, Masaki|Ishii, Hideshi
PMID: 27824159
Journal: Oncotarget. 2016 Nov 8;7(45):73638-73650.
Title: Decreased expression of IDH1-R132H correlates with poor survival in gastrointestinal cancer.
Author: Li, Jieying|Huang, Jianfei|Huang, Fang|Jin, Qing|Zhu, Huijun|Wang, Xudong|Chen, Meng
PMID: 27655638
Journal: Gastroenterology. 2016 Aug;151(2):278-287.e6.
Title: Genomic Alterations Observed in Colitis-Associated Cancers Are Distinct From Those Found in Sporadic Colorectal Cancers and Vary by Type of Inflammatory Bowel Disease.
Author: Yaeger, Rona|Shah, Manish A|Miller, Vincent A|Kelsen, Judith R|Wang, Kai|Heins, Zachary J|Ross, Jeffrey S|He, Yuting|Sanford, Eric|Yantiss, Rhonda K|Balasubramanian, Sohail|Stephens, Philip J|Schultz, Nikolaus|Oren, Moshe|Tang, Laura|Kelsen, David
PMID: 27063727
Journal: Oncotarget. 2017 Jun 14;8(34):57845-57854.
Title: Implementation and utilization of the molecular tumor board to guide precision medicine.
Author: Harada, Shuko|Arend, Rebecca|Dai, Qian|Levesque, Jessica A|Winokur, Thomas S|Guo, Rongjun|Heslin, Martin J|Nabell, Lisle|Nabors, L Burt|Limdi, Nita A|Roth, Kevin A|Partridge, Edward E|Siegal, Gene P|Yang, Eddy S
PMID: 28915716
Journal: Mol Nutr Food Res. 2018 May;62(10):e1700932.
Title: Butyrate Inhibits Indices of Colorectal Carcinogenesis via Enhancing alpha-Ketoglutarate-Dependent DNA Demethylation of Mismatch Repair Genes.
Author: Sun, Xiaofei|Zhu, Mei-Jun
PMID: 29577594
Journal: Inflamm Bowel Dis. 2018 Jul 12;24(8):1780-1790.
Title: Distinct Histopathologic and Molecular Alterations in Inflammatory Bowel Disease-Associated Intestinal Adenocarcinoma: c-MYC Amplification is Common and Associated with Mucinous/Signet Ring Cell Differentiation.
Author: Hartman, Douglas J|Binion, David G|Regueiro, Miguel D|Miller, Caitlyn|Herbst, Cameron|Pai, Reetesh K
PMID: 29788391
Journal: Life Sci. 2018 Aug 15;207:80-89.
Title: Supra-physiological concentration of glyoxylate inhibits proliferation of human colon cancer cells through oxidative stress.
Author: Patra, Tapas|Ghosh, Paramita|Alam, Neyaz|Murmu, Nabendu
PMID: 29852189
Journal: Eur J Surg Oncol. 2018 Aug;44(8):1254-1260.
Title: Correlation of IDH1 and B7H3 expression with prognosis of CRC patients.
Author: Wu, Jingyi|Wang, Fang|Liu, Xingxiang|Zhang, Ting|Liu, Fen|Ge, Xiaosong|Mao, Yong|Hua, Dong
PMID: 29871819
Journal: FASEB J. 2018 Jun 7:fj201800547R.
Title: IDH1-mutant cancer cells are sensitive to cisplatin and an IDH1-mutant inhibitor counteracts this sensitivity.
Author: Khurshed, Mohammed|Aarnoudse, Niels|Hulsbos, Renske|Hira, Vashendriya V V|van Laarhoven, Hanneke W M|Wilmink, Johanna W|Molenaar, Remco J|van Noorden, Cornelis J F
PMID: 29879375
Journal: J Exp Clin Cancer Res. 2018 Sep 12;37(1):225.
Title: LGR5, a novel functional glioma stem cell marker, promotes EMT by activating the Wnt/beta-catenin pathway and predicts poor survival of glioma patients.
Author: Zhang, Jin|Cai, Hongqing|Sun, Lixin|Zhan, Panpan|Chen, Meng|Zhang, Feng|Ran, Yuliang|Wan, Jinghai
PMID: 30208924