Primary Site >> Colorectal Cancer
Gene >> HUWE1
| 1. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2005 Jan 7;326(1):7-17. | ||||||||||
| Title: | Over-expression of human UREB1 in colorectal cancer: HECT domain of human UREB1 inhibits the activity of tumor suppressor p53 protein. | ||||||||||
| Author: | Yoon, Sun Young|Lee, Younghee|Kim, Joo Heon|Chung, An-Sik|Joo, Joung Hyuck|Kim, Chang-Nam|Kim, Nam-Soon|Choe, In Seong|Kim, Jae Wha | ||||||||||
| PMID: | 15567145 | ||||||||||
| 2. | |||||||||||
| Journal: | EMBO Mol Med. 2014 Dec;6(12):1525-41. | ||||||||||
| Title: | Tumor cell-specific inhibition of MYC function using small molecule inhibitors of the HUWE1 ubiquitin ligase. | ||||||||||
| Author: | Peter, Stefanie|Bultinck, Jennyfer|Myant, Kevin|Jaenicke, Laura A|Walz, Susanne|Muller, Judith|Gmachl, Michael|Treu, Matthias|Boehmelt, Guido|Ade, Carsten P|Schmitz, Werner|Wiegering, Armin|Otto, Christoph|Popov, Nikita|Sansom, Owen|Kraut, Norbert|Eilers, | ||||||||||
| PMID: | 25253726 | ||||||||||
| 3. | |||||||||||
| Journal: | Cell Stem Cell. 2016 Aug 4;19(2):205-216. | ||||||||||
| Title: | Mule Regulates the Intestinal Stem Cell Niche via the Wnt Pathway and Targets EphB3 for Proteasomal and Lysosomal Degradation. | ||||||||||
| Author: | Dominguez-Brauer, Carmen|Hao, Zhenyue|Elia, Andrew J|Fortin, Jerome M|Nechanitzky, Robert|Brauer, Patrick M|Sheng, Yi|Mana, Miyeko D|Chio, Iok In Christine|Haight, Jillian|Pollett, Aaron|Cairns, Robert|Tworzyanski, Leanne|Inoue, Satoshi|Reardon, Colin|Mar | ||||||||||
| PMID: | 27184401 | ||||||||||
| 4. | |||||||||||
| Journal: | Oncotarget. 2016 Sep 13;7(37):59503-59518. | ||||||||||
| Title: | Metformin enhances TRAIL-induced apoptosis by Mcl-1 degradation via Mule in colorectal cancer cells. | ||||||||||
| Author: | Park, Seong Hye|Lee, Dae-Hee|Kim, Jung Lim|Kim, Bo Ram|Na, Yoo Jin|Jo, Min Jee|Jeong, Yoon A|Lee, Suk-Young|Lee, Sun Il|Lee, Yong Yook|Oh, Sang Cheul | ||||||||||
| PMID: | 27517746 | ||||||||||
| 5. | |||||||||||
| Journal: | EMBO Mol Med. 2017 Feb;9(2):181-197. | ||||||||||
| Title: | HUWE1 is a critical colonic tumour suppressor gene that prevents MYC signalling, DNA damage accumulation and tumour initiation. | ||||||||||
| Author: | Myant, Kevin B|Cammareri, Patrizia|Hodder, Michael C|Wills, Jimi|Von Kriegsheim, Alex|Gyorffy, Balazs|Rashid, Mamun|Polo, Simona|Maspero, Elena|Vaughan, Lynsey|Gurung, Basanta|Barry, Evan|Malliri, Angeliki|Camargo, Fernando|Adams, David J|Iavarone, Antoni | ||||||||||
| PMID: | 28003334 | ||||||||||
| 6. | |||||||||||
| Journal: | PLoS One. 2017 Jan 20;12(1):e0170551. | ||||||||||
| Title: | Cudraflavone C Induces Tumor-Specific Apoptosis in Colorectal Cancer Cells through Inhibition of the Phosphoinositide 3-Kinase (PI3K)-AKT Pathway. | ||||||||||
| Author: | Soo, Hsien-Chuen|Chung, Felicia Fei-Lei|Lim, Kuan-Hon|Yap, Veronica Alicia|Bradshaw, Tracey D|Hii, Ling-Wei|Tan, Si-Hoey|See, Sze-Jia|Tan, Yuen-Fen|Leong, Chee-Onn|Mai, Chun-Wai | ||||||||||
| PMID: | 28107519 | ||||||||||
| 7. | |||||||||||
| Journal: | Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):E1148-E1157. | ||||||||||
| Title: | E3 ubiquitin ligase Mule targets beta-catenin under conditions of hyperactive Wnt signaling. | ||||||||||
| Author: | Dominguez-Brauer, Carmen|Khatun, Rahima|Elia, Andrew J|Thu, Kelsie L|Ramachandran, Parameswaran|Baniasadi, Shakiba P|Hao, Zhenyue|Jones, Lisa D|Haight, Jillian|Sheng, Yi|Mak, Tak W | ||||||||||
| PMID: | 28137882 | ||||||||||