Primary Site >> Colorectal Cancer

Gene >> HSPA5

Journal: Int J Cancer. 1994 Feb 1;56(3):400-5.
Title: Expression of the 100-kda glucose-regulated protein (GRP100/endoplasmin) is associated with tumorigenicity in a model of rat colon adenocarcinoma.
Author: Menoret, A|Meflah, K|Le Pendu, J
PMID: 8314328
Journal: Surg Oncol. 1995 Aug;4(4):197-203.
Title: Heat shock proteins are differentially expressed in human gastrointestinal cancers.
Author: Ehrenfried, J A|Herron, B E|Townsend, C M Jr|Evers, B M
PMID: 8528482
Journal: Oncol Res. 1995;7(12):583-90.
Title: Glucose-regulated stresses confer resistance to VP-16 in human cancer cells through a decreased expression of DNA topoisomerase II.
Author: Yun, J|Tomida, A|Nagata, K|Tsuruo, T
PMID: 8704275
Journal: Jpn J Cancer Res. 1998 Nov;89(11):1169-78.
Title: A novel mutant from apoptosis-resistant colon cancer HT-29 cells showing hyper-apoptotic response to hypoxia, low glucose and cisplatin.
Author: Suzuki, H|Tomida, A|Tsuruo, T
PMID: 9914786
Journal: Biochem Biophys Res Commun. 1999 Apr 13;257(2):361-8.
Title: Increased sensitivity of human colon cancer cells to DNA cross-linking agents after GRP78 up-regulation.
Author: Belfi, C A|Chatterjee, S|Gosky, D M|Berger, S J|Berger, N A
PMID: 10198218
Journal: Carcinogenesis. 2002 Dec;23(12):2063-80.
Title: Development and molecular characterization of HCT-116 cell lines resistant to the tumor promoter and multiple stress-inducer, deoxycholate.
Author: Crowley-Weber, Cara L|Payne, Claire M|Gleason-Guzman, Mary|Watts, George S|Futscher, Bernard|Waltmire, Caroline N|Crowley, Cheray|Dvorakova, Katerina|Bernstein, Carol|Craven, Mary|Garewal, Harinder|Bernstein, Harris
PMID: 12507930
Journal: Chem Biol Interact. 2003 Mar 6;145(1):53-66.
Title: Nicotine increases oxidative stress, activates NF-kappaB and GRP78, induces apoptosis and sensitizes cells to genotoxic/xenobiotic stresses by a multiple stress inducer, deoxycholate: relevance to colon carcinogenesis.
Author: Crowley-Weber, Cara L|Dvorakova, Katerina|Crowley, Cheray|Bernstein, Harris|Bernstein, Carol|Garewal, Harinder|Payne, Claire M
PMID: 12606154
Journal: Cancer Lett. 2004 May 28;208(2):143-53.
Title: Critical roles of intracellular thiols and calcium in parthenolide-induced apoptosis in human colorectal cancer cells.
Author: Zhang, Siyuan|Ong, Choon-Nam|Shen, Han-Ming
PMID: 15142672
Journal: Clin Cancer Res. 2004 Jul 1;10(13):4498-508.
Title: Effective photoimmunotherapy of murine colon carcinoma induced by the combination of photodynamic therapy and dendritic cells.
Author: Jalili, Ahmad|Makowski, Marcin|Switaj, Tomasz|Nowis, Dominika|Wilczynski, Grzegorz M|Wilczek, Ewa|Chorazy-Massalska, Magdalena|Radzikowska, Anna|Maslinski, Wlodzimierz|Bialy, Lukasz|Sienko, Jacek|Sieron, Aleksander|Adamek, Mariusz|Basak, Grzegorz|Mroz, Pa
PMID: 15240542
Journal: J Natl Cancer Inst. 2004 Sep 1;96(17):1300-10.
Title: Effect on tumor cells of blocking survival response to glucose deprivation.
Author: Park, Hae-Ryong|Tomida, Akihiro|Sato, Shigeo|Tsukumo, Yoshinori|Yun, Jisoo|Yamori, Takao|Hayakawa, Yoichi|Tsuruo, Takashi|Shin-ya, Kazuo
PMID: 15339968
Journal: Int J Biochem Cell Biol. 2005 Jun;37(6):1254-68. Epub 2005 Jan 21.
Title: Expression of stress response protein glucose regulated protein-78 mediated by c-Myb.
Author: Ramsay, Robert G|Ciznadija, Daniel|Mantamadiotis, Theo|Anderson, Robin|Pearson, Richard
PMID: 15778089
Journal: Clin Chim Acta. 2006 Feb;364(1-2):308-15.
Title: Overexpression of glucose-regulated protein 78 in colon cancer.
Author: Xing, Xiaoming|Lai, Maode|Wang, Yinghong|Xu, Enping|Huang, Qiong
PMID: 16182273
Journal: Carcinogenesis. 2006 Sep;27(9):1812-27. Epub 2006 Mar 7.
Title: Dihydroxyphenylethanol induces apoptosis by activating serine/threonine protein phosphatase PP2A and promotes the endoplasmic reticulum stress response in human colon carcinoma cells.
Author: Guichard, Cecile|Pedruzzi, Eric|Fay, Michele|Marie, Jean-Claude|Braut-Boucher, Francoise|Daniel, Fanny|Grodet, Alain|Gougerot-Pocidalo, Marie-Anne|Chastre, Eric|Kotelevets, Larissa|Lizard, Gerard|Vandewalle, Alain|Driss, Fathi|Ogier-Denis, Eric
PMID: 16524888
Journal: Biol Pharm Bull. 2006 Apr;29(4):817-20.
Title: Selective cytotoxic activity of valinomycin against HT-29 Human colon carcinoma cells via down-regulation of GRP78.
Author: Ryoo, In-Ja|Park, Hae-Ryong|Choo, Soo-Jin|Hwang, Ji-Hwan|Park, Young-Min|Bae, Ki-Hwan|Shin-Ya, Kazuo|Yoo, Ick-Dong
PMID: 16595926
Journal: Toxicology. 2007 Jan 18;229(3):253-61.
Title: Glucose-deprived HT-29 human colon carcinoma cells are sensitive to verrucosidin as a GRP78 down-regulator.
Author: Park, Hae-Ryong|Ryoo, In-Ja|Choo, Soo-Jin|Hwang, Ji-Hwan|Kim, Ju-Young|Cha, Mi-Ran|Shin-Ya, Kazuo|Yoo, Ick-Dong
PMID: 17161515
Journal: Cancer Res. 2007 Feb 1;67(3):1262-9.
Title: Inhibition of fatty acid synthase induces endoplasmic reticulum stress in tumor cells.
Author: Little, Joy L|Wheeler, Frances B|Fels, Diane R|Koumenis, Constantinos|Kridel, Steven J
PMID: 17283163
Journal: Zhonghua Bing Li Xue Za Zhi. 2007 Feb;36(2):107-12.
Title: [Differential expression of secretagogin and glucose-related protein 78 in colorectal carcinoma: a proteome study].
Author: Xing, Xiao-Ming|Wang, Ying-Hong|Huang, Qiong|Lu, Bing-Jian|Lai, Mao-de
PMID: 17493385
Journal: J Cell Physiol. 2008 Apr;215(1):243-50.
Title: Etoposide-resistant HT-29 human colon carcinoma cells during glucose deprivation are sensitive to piericidin A, a GRP78 down-regulator.
Author: Hwang, Ji-Hwan|Kim, Ju-Young|Cha, Mi-Ran|Ryoo, In-Ja|Choo, Soo-Jin|Cho, Sung-Min|Tsukumo, Yoshinori|Tomida, Akihiro|Shin-Ya, Kazuo|Hwang, Yong-Il|Yoo, Ick-Dong|Park, Hae-Ryong
PMID: 17941090
Journal: Mol Cancer Ther. 2008 Oct;7(10):3429-40.
Title: 15-deoxy-Delta12,14-prostaglandin J2 up-regulates death receptor 5 gene expression in HCT116 cells: involvement of reactive oxygen species and C/EBP homologous transcription factor gene transcription.
Author: Su, Rong-Ying|Chi, Kwan-Hwa|Huang, Duen-Yi|Tai, Ming-Hui|Lin, Wan-Wan
PMID: 18852146
Journal: Langenbecks Arch Surg. 2009 Jul;394(4):681-8.
Title: Extended liver resection after preoperative chemotherapy: influence on regeneration and endoplasmic reticulum stress response.
Author: Manekeller, Steffen|Seinsche, Alexandra|Sioutis, Maria|Hirner, Andreas
PMID: 18688639
Journal: Biochem Biophys Res Commun. 2009 Feb 6;379(2):514-8.
Title: Tosylcyclonovobiocic acids promote cleavage of the hsp90-associated cochaperone p23.
Author: Radanyi, Christine|Le Bras, Gaelle|Bouclier, Celine|Messaoudi, Samir|Peyrat, Jean-Francois|Brion, Jean-Daniel|Alami, Mouad|Renoir, Jack-Michel
PMID: 19118525
Journal: Br J Cancer. 2009 Jul 7;101(1):116-23.
Title: High Ki67, Bax, and thymidylate synthase expression well correlates with response to chemoradiation therapy in locally advanced rectal cancers: proposal of a logistic model for prediction.
Author: Kikuchi, M|Mikami, T|Sato, T|Tokuyama, W|Araki, K|Watanabe, M|Saigenji, K|Okayasu, I
PMID: 19491899
Journal: Anticancer Drugs. 2009 Aug;20(7):601-6.
Title: Inhibition of MEK sensitizes paclitaxel-induced apoptosis of human colorectal cancer cells by downregulation of GRP78.
Author: Mhaidat, Nizar M|Alali, Feras Q|Matalqah, Sina M|Matalka, Ismail I|Jaradat, Saied A|Al-Sawalha, Nour A|Thorne, Rick F
PMID: 19521235
Journal: Toxicol Appl Pharmacol. 2009 Dec 15;241(3):348-55.
Title: Thioredoxin reductase 1 ablation sensitizes colon cancer cells to methylseleninate-mediated cytotoxicity.
Author: Honeggar, Matthew|Beck, Robert|Moos, Philip J
PMID: 19782697
Journal: Carcinogenesis. 2010 Apr;31(4):703-11.
Title: The integrated stress response-associated signals modulates intestinal tumor cell growth by NSAID-activated gene 1 (NAG-1/MIC-1/PTGF-beta).
Author: Yang, Hyun|Park, Seong Hwan|Choi, Hye Jin|Moon, Yuseok
PMID: 20130018
Journal: Biochem Pharmacol. 2010 Jun 1;79(11):1589-99.
Title: Bax deficiency mediated drug resistance can be reversed by endoplasmic reticulum stress induced death signaling.
Author: Chandrika, Bhavya Balan|Maney, Sathish Kumar|Lekshmi, Swathi U|Joseph, Jeena|Seervi, Mahendra|K S, Praveen|T R, Santhoshkumar
PMID: 20138027
Journal: J Biol Chem. 2010 Apr 2;285(14):10678-89.
Title: Histone deacetylase inhibitor valproic acid inhibits cancer cell proliferation via down-regulation of the alzheimer amyloid precursor protein.
Author: Venkataramani, Vivek|Rossner, Christian|Iffland, Lara|Schweyer, Stefan|Tamboli, Irfan Y|Walter, Jochen|Wirths, Oliver|Bayer, Thomas A
PMID: 20145244
Journal: Oncol Rep. 2010 Apr;23(4):949-56.
Title: Proteomics-based identification of a tumor-associated antigen and its corresponding autoantibody in gastric cancer.
Author: Tsunemi, Soichiro|Nakanishi, Toyofumi|Fujita, Yoshihisa|Bouras, George|Miyamoto, Yoshiharu|Miyamoto, Akiko|Nomura, Eiji|Takubo, Takayuki|Tanigawa, Nobuhiko
PMID: 20204278
Journal: J Cell Physiol. 2010 Jul;224(1):33-40.
Title: Arctigenin blocks the unfolded protein response and shows therapeutic antitumor activity.
Author: Kim, Ju-Young|Hwang, Ji-Hwan|Cha, Mi-Ran|Yoon, Mi-Young|Son, Eun-Soon|Tomida, Akihiro|Ko, Bosung|Song, Si-Whan|Shin-ya, Kazuo|Hwang, Yong-il|Park, Hae-Ryong
PMID: 20232300
Journal: Lett Appl Microbiol. 2010 Aug;51(2):123-30.
Title: Cell-bound exopolysaccharide from probiotic bacteria induces autophagic cell death of tumour cells.
Author: Kim, Y|Oh, S|Yun, H S|Oh, S|Kim, S H
PMID: 20536712
Journal: J Med Chem. 2010 Nov 25;53(22):8192-6.
Title: Organometallic osmium arene complexes with potent cancer cell cytotoxicity.
Author: Fu, Ying|Habtemariam, Abraha|Pizarro, Ana M|van Rijt, Sabine H|Healey, David J|Cooper, Patricia A|Shnyder, Steven D|Clarkson, Guy J|Sadler, Peter J
PMID: 20977192
Journal: Invest New Drugs. 2011 Dec;29(6):1276-83.
Title: The anti-cancer activity of dihydroartemisinin is associated with induction of iron-dependent endoplasmic reticulum stress in colorectal carcinoma HCT116 cells.
Author: Lu, Jin-Jian|Chen, Si-Meng|Zhang, Xiao-Wei|Ding, Jian|Meng, Ling-Hua
PMID: 20607588
Journal: Acta Histochem. 2011 Dec;113(8):777-82.
Title: Glucose regulated protein 78 (GRP78) is overexpressed in colorectal carcinoma and regulates colorectal carcinoma cell growth and apoptosis.
Author: Xing, Xiaoming|Li, Yujun|Liu, Huamin|Wang, Lili|Sun, Lingling
PMID: 21156321
Journal: J Cell Biochem. 2011 Feb;112(2):643-52.
Title: Phloroglucinol derivative MCPP induces cell apoptosis in human colon cancer.
Author: Huang, Ssu-Ming|Cheung, Chi-Wai|Chang, Chih-Shiang|Tang, Chih-Hsin|Liu, Ju-Fang|Lin, Yu-Hsin|Chen, Jia-Hong|Ko, Shihi-Hsun|Wong, Kar-Lok|Lu, Dah-Yuu
PMID: 21268086
Journal: Ann Oncol. 2011 Nov;22(11):2431-9.
Title: GRP78 promoter polymorphism rs391957 as potential predictor for clinical outcome in gastric and colorectal cancer patients.
Author: Winder, T|Bohanes, P|Zhang, W|Yang, D|Power, D G|Ning, Y|Gerger, A|Wilson, P M|Tang, L H|Shah, M|Lee, A S|Lenz, H-J
PMID: 21382870
Journal: J Dig Dis. 2011 Apr;12(2):110-6.
Title: RNA interference (RNAi) of Ufd1 protein can sensitize a hydroxycamptothecin-resistant colon cancer cell line SW1116/HCPT to hydroxycamptothecin.
Author: Chen, Xiang|Ran, Zhi Hua|Tong, Jin Lu|Nie, Fang|Zhu, Ming Ming|Xu, Xi Tao|Xiao, Shu Dong
PMID: 21401896
Journal: Histol Histopathol. 2011 Jun;26(6):663-71.
Title: Overexpression of GRP78 and GRP94 is involved in colorectal carcinogenesis.
Author: Takahashi, Hiroyuki|Wang, Jian-ping|Zheng, Hua-chuan|Masuda, Shinji|Takano, Yasuo
PMID: 21472681
Journal: Clin Cancer Res. 2011 Jul 1;17(13):4474-83.
Title: The Akt inhibitor ISC-4 activates prostate apoptosis response protein-4 and reduces colon tumor growth in a nude mouse model.
Author: Sharma, Arun K|Kline, Christina L|Berg, Arthur|Amin, Shantu|Irby, Rosalyn B
PMID: 21555373
Journal: Oncol Rep. 2011 Aug;26(2):495-502.
Title: Celecoxib induces cell apoptosis coupled with up-regulation of the expression of VEGF by a mechanism involving ER stress in human colorectal cancer cells.
Author: Du, Hansong|Li, Wei|Wang, Yu|Chen, Sufang|Zhang, Ying
PMID: 21567098
Journal: Cancer Res. 2011 Dec 15;71(24):7659-69.
Title: Sorcin induces a drug-resistant phenotype in human colorectal cancer by modulating Ca(2+) homeostasis.
Author: Maddalena, Francesca|Laudiero, Gabriella|Piscazzi, Annamaria|Secondo, Agnese|Scorziello, Antonella|Lombardi, Valentina|Matassa, Danilo Swann|Fersini, Alberto|Neri, Vincenzo|Esposito, Franca|Landriscina, Matteo
PMID: 22052463
Journal: Cell Death Differ. 2012 Apr;19(4):592-604.
Title: TRAP1 and the proteasome regulatory particle TBP7/Rpt3 interact in the endoplasmic reticulum and control cellular ubiquitination of specific mitochondrial proteins.
Author: Amoroso, M R|Matassa, D S|Laudiero, G|Egorova, A V|Polishchuk, R S|Maddalena, F|Piscazzi, A|Paladino, S|Sarnataro, D|Garbi, C|Landriscina, M|Esposito, F
PMID: 21979464
Journal: Nagoya J Med Sci. 2012 Feb;74(1-2):123-31.
Title: Geranylgeranylacetone attenuates cisplatin-induced reductions in cell viability by suppressing the elevation of intracellular p53 content without heat shock protein induction.
Author: Hasegawa, Motofusa|Ishiguro, Kazuhiro|Ando, Takafumi|Goto, Hidemi
PMID: 22515118
Journal: PLoS One. 2012;7(4):e35123.
Title: GRP78 knockdown enhances apoptosis via the down-regulation of oxidative stress and Akt pathway after epirubicin treatment in colon cancer DLD-1 cells.
Author: Chang, Yu-Jia|Huang, Yi-Ping|Li, Zih-Ling|Chen, Ching-Hsein
PMID: 22529978
Journal: Biochim Biophys Acta. 2012 Nov;1822(11):1762-72.
Title: DHA induces apoptosis by altering the expression and cellular location of GRP78 in colon cancer cell lines.
Author: Fasano, Elena|Serini, Simona|Piccioni, Elisabetta|Toesca, Amelia|Monego, Giovanni|Cittadini, Achille R|Ranelletti, Franco O|Calviello, Gabriella
PMID: 22898250
Journal: Cell Oncol (Dordr). 2012 Oct;35(5):345-54. Epub 2012 Sep 4.
Title: Colon cancer cells expressing cell surface GRP78 as a marker for reduced tumorigenicity.
Author: Hardy, Britta|Raiter, Annat|Yakimov, Maxim|Vilkin, Alexander|Niv, Yaron
PMID: 22945507
Journal: Mol Biosyst. 2012 Nov;8(11):3077-88.
Title: New prognosis biomarkers identified by dynamic proteomic analysis of colorectal cancer.
Author: Peng, Ya|Li, Xiayu|Wu, Minghua|Yang, Jing|Liu, Minji|Zhang, Wengling|Xiang, Bo|Wang, Xiaoyan|Li, Xiaoling|Li, Guiyuan|Shen, Shourong
PMID: 22996014
Journal: J Nat Med. 2013 Jan;67(1):17-26.
Title: Investigation of the extracts from Bidens pilosa Linn. var. radiata Sch. Bip. for antioxidant activities and cytotoxicity against human tumor cells.
Author: Wu, Jianguo|Wan, Zhongxian|Yi, Jun|Wu, Yanbin|Peng, Wei|Wu, Jinzhong
PMID: 22382861
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2013 Jan;16(1):75-9.
Title: [Preliminary study on glucose regulated protein 78 kD and heat shock protein 20 differential expression between left-sided colon carcinoma and right-sided colon carcinoma].
Author: Pei, Hai-ping|Li, Xiao-long|Zhu, Hong|Zeng, Liang|Huang, Lin-sheng
PMID: 23355246
Journal: Oncol Rep. 2013 Apr;29(4):1365-70.
Title: 20-O-(beta-D-glucopyranosyl)-20(S)-protopanaxadiol induces apoptosis via induction of endoplasmic reticulum stress in human colon cancer cells.
Author: Zhang, Rui|Chung, Young|Kim, Hee Sun|Kim, Dong Hyun|Kim, Hye Sun|Chang, Weon Young|Hyun, Jin Won
PMID: 23381572
Journal: Int J Cancer. 2013 Sep 15;133(6):1408-18.
Title: The unfolded protein response regulator GRP78 is a novel predictive biomarker in colorectal cancer.
Author: Thornton, Michael|Aslam, Mohammed A|Tweedle, Elizabeth M|Ang, Chin|Campbell, Fiona|Jackson, Richard|Costello, Eithne|Rooney, Paul S|Vlatkovic, Nikolina|Boyd, Mark T
PMID: 23456958
Journal: Int J Biochem Cell Biol. 2013 May;45(5):987-94.
Title: Cell-surface GRP78 facilitates colorectal cancer cell migration and invasion.
Author: Li, Zongwei|Zhang, Lichao|Zhao, Yarui|Li, Hanqing|Xiao, Hong|Fu, Rong|Zhao, Chao|Wu, Haili|Li, Zhuoyu
PMID: 23485528
Journal: J Surg Res. 2013 Nov;185(1):264-72.
Title: Glucose-regulated protein 78 silencing down-regulates vascular endothelial growth factor/vascular endothelial growth factor receptor 2 pathway to suppress human colon cancer tumor growth.
Author: Kuo, Li-Jen|Hung, Chin-Sheng|Chen, Wei-Yu|Chang, Yu-Jia|Wei, Po-Li
PMID: 23759331
Journal: PLoS One. 2013 Jun 20;8(6):e66791.
Title: Polymorphisms of glucose-regulated protein 78 and risk of colorectal cancer: a case-control study in southwest China.
Author: Zhang, Dan|Zhou, Bin|Li, Yuan|Wang, Mojin|Wang, Cun|Zhou, Zongguang|Sun, Xiaofeng
PMID: 23818965
Journal: Molecules. 2013 Aug 22;18(9):10242-53.
Title: Brefeldin a effectively inhibits cancer stem cell-like properties and MMP-9 activity in human colorectal cancer Colo 205 cells.
Author: Tseng, Chao-Neng|Huang, Chien-Fu|Cho, Chung-Lung|Chang, Hsueh-Wei|Huang, Chao-Wei|Chiu, Chien-Chih|Chang, Yung-Fu
PMID: 23973996
Journal: Asian Pac J Cancer Prev. 2013;14(7):4249-54.
Title: Effects of parafibromin expression on the phenotypes and relevant mechanisms in the DLD-1 colon carcinoma cell line.
Author: Zhao, Shuang|Sun, Hong-Zhi|Zhu, Shi-Tu|Lu, Hang|Niu, Zhe-Feng|Guo, Wen-Feng|Takano, Yasuo|Zheng, Hua-Chuan
PMID: 23991985
Journal: Cell Death Dis. 2013 Oct 10;4:e851.
Title: Translational control in the stress adaptive response of cancer cells: a novel role for the heat shock protein TRAP1.
Author: Matassa, D S|Amoroso, M R|Agliarulo, I|Maddalena, F|Sisinni, L|Paladino, S|Romano, S|Romano, M F|Sagar, V|Loreni, F|Landriscina, M|Esposito, F
PMID: 24113185
Journal: Sci Rep. 2013 Nov 14;3:3219.
Title: Zebularine inhibits tumorigenesis and stemness of colorectal cancer via p53-dependent endoplasmic reticulum stress.
Author: Yang, Pei-Ming|Lin, Yi-Ting|Shun, Chia-Tung|Lin, Shan-Hu|Wei, Tzu-Tang|Chuang, Shu-Hui|Wu, Ming-Shiang|Chen, Ching-Chow
PMID: 24225777
Journal: Mol Med Rep. 2014 Jan;9(1):243-8.
Title: Caffeine inhibits paclitaxelinduced apoptosis in colorectal cancer cells through the upregulation of Mcl1 levels.
Author: Mhaidat, Nizar M|Alzoubi, Karem H|Al-Azzam, Sayer I|Alsaad, Alhareth A
PMID: 24173825
Journal: BMB Rep. 2014 Aug;47(8):445-50.
Title: Glucose regulated protein 78 promotes cell invasion via regulation of uPA production and secretion in colon cancer cells.
Author: Li, Zongwei|Zhang, Lichao|Li, Hanqing|Shan, Shuhua|Li, Zhuoyu
PMID: 24314144
Journal: Acta Pharmacol Sin. 2014 Mar;35(3):394-400.
Title: OSU-CG5, a novel energy restriction mimetic agent, targets human colorectal cancer cells in vitro.
Author: Arafa, El-shaimaa A|Abdelazeem, Ahmed H|Arab, Hany H|Omar, Hany A
PMID: 24464048
Journal: PLoS One. 2014 Apr 3;9(4):e93794.
Title: Suppression of colorectal cancer liver metastasis by apolipoprotein(a) kringle V in a nude mouse model through the induction of apoptosis in tumor-associated endothelial cells.
Author: Ahn, Jin-Hyung|Yu, Hyun-Kyung|Lee, Ho-Jeong|Hong, Soon Won|Kim, Sun Jin|Kim, Jang-Seong
PMID: 24699568
Journal: Int J Biol Markers. 2014 Dec 9;29(4):e431-5.
Title: The presence of anti-GRP78 antibodies in the serum of patients with colorectal carcinoma: a potential biomarker for early cancer detection.
Author: Raiter, Annat|Vilkin, Alexander|Gingold, Rachel|Levi, Zohar|Halpern, Marisa|Niv, Yaron|Hardy, Britta
PMID: 24803280
Journal: Int J Oncol. 2014 Jul;45(1):31-40.
Title: Cripto haploinsufficiency affects in vivo colon tumor development.
Author: Giorgio, Emilia|Liguoro, Annamaria|D'Orsi, Luca|Mancinelli, Sara|Barbieri, Antonio|Palma, Giuseppe|Arra, Claudio|Liguori, Giovanna L
PMID: 24805056
Journal: Br J Cancer. 2014 Jul 29;111(3):497-505.
Title: Statins, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors, potentiate the anti-angiogenic effects of bevacizumab by suppressing angiopoietin2, BiP, and Hsp90alpha in human colorectal cancer.
Author: Lee, S J|Lee, I|Lee, J|Park, C|Kang, W K
PMID: 24945998
Journal: J Dig Dis. 2014 Sep;15(9):491-500.
Title: Silencing of JMJD2B induces cell apoptosis via mitochondria-mediated and death receptor-mediated pathway activation in colorectal cancer.
Author: Sun, Bei Bei|Fu, Lin Na|Wang, Yun Qian|Gao, Qin Yan|Xu, Jie|Cao, Zhi Jun|Chen, Ying Xuan|Fang, Jing Yuan
PMID: 24957706
Journal: Oncotarget. 2014 Jul 30;5(14):5369-80.
Title: GRP78 enhances the glutamine metabolism to support cell survival from glucose deficiency by modulating the beta-catenin signaling.
Author: Li, Zongwei|Wang, Yingying|Wu, Haili|Zhang, Lichao|Yang, Peng|Li, Zhuoyu
PMID: 24977433
Journal: Asian Pac J Cancer Prev. 2014;15(17):7245-9.
Title: GRP78 secreted by colon cancer cells facilitates cell proliferation via PI3K/Akt signaling.
Author: Fu, Rong|Yang, Peng|Wu, Hai-Li|Li, Zong-Wei|Li, Zhuo-Yu
PMID: 25227822
Journal: PLoS One. 2014 Sep 18;9(9):e108157.
Title: Fucoidan induces cancer cell apoptosis by modulating the endoplasmic reticulum stress cascades.
Author: Chen, Shaohua|Zhao, Yang|Zhang, Yu|Zhang, Daohai
PMID: 25232957
Journal: BMC Complement Altern Med. 2014 Oct 15;14:401.
Title: Astragalus saponins modulates colon cancer development by regulating calpain-mediated glucose-regulated protein expression.
Author: Wang, Yue|Auyeung, Kathy K|Zhang, Xiaoyu|Ko, Joshua K
PMID: 25319833
Journal: Tumour Biol. 2015 Feb;36(2):633-41.
Title: GRP78 mediates the therapeutic efficacy of curcumin on colon cancer.
Author: Chang, Yu-Jia|Huang, Chien-Yu|Hung, Chin-Sheng|Chen, Wei-Yu|Wei, Po-Li
PMID: 25277658
Journal: Tumour Biol. 2015 Mar;36(3):1859-69.
Title: Glucose-regulated protein 78 (GRP78) regulates colon cancer metastasis through EMT biomarkers and the NRF-2/HO-1 pathway.
Author: Chang, Yu-Jia|Chen, Wei-Yu|Huang, Chien-Yu|Liu, Hui-Hsiung|Wei, Po-Li
PMID: 25431258
Journal: Cancer Biomark. 2015;15(2):197-203.
Title: Expression of glucose regulated protein 78 (GRP78) determines colorectal cancer response to chemotherapy.
Author: Mhaidat, Nizar M|Alzoubi, Karem H|Almomani, Nabeela|Khabour, Omar F
PMID: 25519021
Journal: Toxicol Sci. 2015 Apr;144(2):328-37.
Title: Patulin induces apoptosis through ROS-mediated endoplasmic reticulum stress pathway.
Author: Boussabbeh, Manel|Ben Salem, Intidhar|Prola, Alexandre|Guilbert, Arnaud|Bacha, Hassen|Abid-Essefi, Salwa|Lemaire, Christophe
PMID: 25577197
Journal: Tumour Biol. 2015 Jun;36(6):4367-76.
Title: Glucose-regulated protein 78 mediates the therapeutic efficacy of 17-DMAG in colon cancer cells.
Author: Chang, Yu-Jia|Huang, Chien-Yu|Hung, Chin-Sheng|Liu, Hui-Hsiung|Wei, Po-Li
PMID: 25618598
Journal: Cancer Res Treat. 2015 Oct;47(4):804-12.
Title: GRP78 Protein Expression as Prognostic Values in Neoadjuvant Chemoradiotherapy and Laparoscopic Surgery for Locally Advanced Rectal Cancer.
Author: Lee, Hee Yeon|Jung, Ji-Han|Cho, Hyun-Min|Kim, Sung Hwan|Lee, Kang-Moon|Kim, Hyung-Jin|Lee, Jong Hoon|Shim, Byoung Yong
PMID: 25687871
Journal: Chem Biol Interact. 2015 May 5;232:58-67.
Title: A therapeutically relevant, 3,3'-diindolylmethane derivative NGD16 attenuates angiogenesis by targeting glucose regulated protein, 78kDa (GRP78).
Author: Nayak, Debasis|Amin, Hina|Rah, Bilal|Ur Rasool, Reyaz|Sharma, Deepak|Gupta, Ajai Prakash|Kushwaha, Manoj|Mukherjee, Debaraj|Goswami, Anindya
PMID: 25794856
Journal: Int J Biochem Cell Biol. 2015 Jul;64:202-11.
Title: Overexpressed GRP78 affects EMT and cell-matrix adhesion via autocrine TGF-beta/Smad2/3 signaling.
Author: Zhang, Lichao|Li, Zongwei|Fan, Yongsheng|Li, Hanqing|Li, Zhouyu|Li, Yaoping
PMID: 25934251
Journal: Biomed Res Int. 2015;2015:968743.
Title: A Survival Association Study of 102 Polymorphisms Previously Associated with Survival Outcomes in Colorectal Cancer.
Author: Savas, Sevtap|Xu, Jingxiong|Werdyani, Salem|Shestopaloff, Konstantin|Dicks, Elizabeth|Green, Jane|Parfrey, Patrick|Green, Roger|Xu, Wei
PMID: 26064972
Journal: Anticancer Drugs. 2015 Oct;26(9):964-73.
Title: The interplay between GRP78 expression and Akt activation in human colon cancer cells under celecoxib treatment.
Author: Tian, Shaobo|Chang, Weilong|Du, Hansong|Bai, Jie|Sun, Zhenhai|Zhang, Qing|Wang, Hui|Zhu, Guangsheng|Tao, Kaixiong|Long, Yueping
PMID: 26225471
Journal: BMC Cancer. 2015 Oct 12;15:682.
Title: Hesperidin inhibits HeLa cell proliferation through apoptosis mediated by endoplasmic reticulum stress pathways and cell cycle arrest.
Author: Wang, Yaoxian|Yu, Hui|Zhang, Jin|Gao, Jing|Ge, Xin|Lou, Ge
PMID: 26459308
Journal: BMC Cancer. 2015 Oct 24;15:795.
Title: Inhibition of autophagy exerts anti-colon cancer effects via apoptosis induced by p53 activation and ER stress.
Author: Sakitani, Kosuke|Hirata, Yoshihiro|Hikiba, Yohko|Hayakawa, Yoku|Ihara, Sozaburo|Suzuki, Hirobumi|Suzuki, Nobumi|Serizawa, Takako|Kinoshita, Hiroto|Sakamoto, Kei|Nakagawa, Hayato|Tateishi, Keisuke|Maeda, Shin|Ikenoue, Tsuneo|Kawazu, Shoji|Koike, Kazuhiko
PMID: 26496833
Journal: Cytotechnology. 2016 May;68(3):459-67.
Title: GRP78 regulates sensitivity of human colorectal cancer cells to DNA targeting agents.
Author: Mhaidat, Nizar M|Alzoubi, Karem H|Khabour, Omar F|Banihani, Mohammed N|Al-Balas, Qosay A|Swaidan, Sulaiman
PMID: 25399254
Journal: Environ Toxicol. 2016 Aug;31(8):957-69.
Title: Crude extract of Rheum palmatum L. Induces cell cycle arrest S phase and apoptosis through mitochondrial-dependent pathways in U-2 OS human osteosarcoma cells.
Author: Lin, Chin-Chung|Lee, Ming-Huei|Lin, Ju-Hwa|Lin, Meng-Liang|Chueh, Fu-Shin|Yu, Chien-Chih|Lin, Jing-Pin|Chou, Yu-Cheng|Hsu, Shu-Chun|Chung, Jing-Gung
PMID: 25689151
Journal: Oncogene. 2016 Jan 21;35(3):333-43.
Title: Mitochondrial ATAD3A combines with GRP78 to regulate the WASF3 metastasis-promoting protein.
Author: Teng, Y|Ren, X|Li, H|Shull, A|Kim, J|Cowell, J K
PMID: 25823022
Journal: J Cell Biochem. 2016 May;117(5):1078-91.
Title: TRAIL-Induced Caspase Activation Is a Prerequisite for Activation of the Endoplasmic Reticulum Stress-Induced Signal Transduction Pathways.
Author: Lee, Dae-Hee|Sung, Ki Sa|Guo, Zong Sheng|Kwon, William Taehyung|Bartlett, David L|Oh, Sang Cheul|Kwon, Yong Tae|Lee, Yong J
PMID: 26212606
Journal: Environ Toxicol. 2016 Dec;31(12):1851-1858.
Title: Crocin and quercetin prevent PAT-induced apoptosis in mammalian cells: Involvement of ROS-mediated ER stress pathway.
Author: Boussabbeh, Manel|Prola, Alexandre|Ben Salem, Intidhar|Guilbert, Arnaud|Bacha, Hassen|Lemaire, Christophe|Abis-Essefi, Salwa
PMID: 26314699
Journal: Tumour Biol. 2016 May;37(5):6501-10.
Title: FAM172A is a tumor suppressor in colorectal carcinoma.
Author: Cui, Chunhui|Ye, Lili|Huang, Zonghai|Huang, Shuxin|Liu, Hao|Yu, Jinlong
PMID: 26637224
Journal: PLoS One. 2016 Jan 19;11(1):e0147218.
Title: Sodium Butyrate Induces Endoplasmic Reticulum Stress and Autophagy in Colorectal Cells: Implications for Apoptosis.
Author: Zhang, Jintao|Yi, Man|Zha, Longying|Chen, Siqiang|Li, Zhijia|Li, Cheng|Gong, Mingxing|Deng, Hong|Chu, Xinwei|Chen, Jiehua|Zhang, Zheqing|Mao, Limei|Sun, Suxia
PMID: 26784903
Journal: Onco Targets Ther. 2016 Feb 3;9:627-34.
Title: Potassium-3-beta-hydroxy-20-oxopregn-5-en-17-alpha-yl sulfate: a novel inhibitor of 78 kDa glucose-regulated protein.
Author: Mhaidat, Nizar M|Al-Balas, Qosay A|Alzoubi, Karem H|AlEjielat, Rowan F
PMID: 26893572
Journal: Cancer Chemother Pharmacol. 2016 Apr;77(4):797-806.
Title: Celecoxib induces apoptosis but up-regulates VEGF via endoplasmic reticulum stress in human colorectal cancer in vitro and in vivo.
Author: Xu, Bingfei|Wang, Yu|Yang, Jing|Zhang, Zhengfeng|Zhang, Ying|Du, Hansong
PMID: 26931344
Journal: Invest New Drugs. 2016 Jun;34(3):261-8.
Title: Molecular mode of action of NKP-1339 - a clinically investigated ruthenium-based drug - involves ER- and ROS-related effects in colon carcinoma cell lines.
Author: Flocke, Lea S|Trondl, Robert|Jakupec, Michael A|Keppler, Bernhard K
PMID: 26988975
Journal: Oncotarget. 2016 May 3;7(18):26480-95.
Title: FOXM1 promotes invasion and migration of colorectal cancer cells partially dependent on HSPA5 transactivation.
Author: Luo, Xiaoyong|Yao, Jinke|Nie, Peipei|Yang, Zhiyuan|Feng, Hongbo|Chen, Pinjia|Shi, Xinpeng|Zou, Zhengzhi
PMID: 27034162
Journal: Environ Toxicol Pharmacol. 2016 Jun;44:128-33.
Title: Endoplasmic reticulum stress induces 5-fluorouracil resistance in human colon cancer cells.
Author: Kim, Joon Ki|Kang, Kyoung Ah|Piao, Mei Jing|Ryu, Yea Seong|Han, Xia|Fernando, Pattage Madushan Dilhara Jayatissa|Oh, Min Chang|Park, Jeong Eon|Shilnikova, Kristina|Boo, Sun Jin|Na, Soo-Young|Jeong, Yong Joo|Jeong, Seung Uk|Hyun, Jin Won
PMID: 27163731
Journal: Oncotarget. 2016 Jul 5;7(27):41432-41444.
Title: Endoplasmic reticulum stress and IRE-1 signaling cause apoptosis in colon cancer cells in response to andrographolide treatment.
Author: Banerjee, Aditi|Ahmed, Hafiz|Yang, Peixin|Czinn, Steven J|Blanchard, Thomas G
PMID: 27166181
Journal: Virchows Arch. 2016 Aug;469(2):145-54.
Title: Endoplasmic reticulum stress, unfolded protein response and development of colon adenocarcinoma.
Author: Piton, Nicolas|Wason, James|Colasse, Elodie|Cornic, Marie|Lemoine, Francoise|Le Pessot, Florence|Marguet, Florent|Sabourin, Jean-Christophe
PMID: 27220766
Journal: Zhonghua Bing Li Xue Za Zhi. 2016 Jun 8;45(6):401-6.
Title: [Roles of glucose-regulated protein 78 in proliferation and migration of human colorectal carcinoma cell line RKO].
Author: Ji, Q X|Liu, L L|Li, L|Xing, X M
PMID: 27256049
Journal: J Transl Med. 2016 Jul 1;14(1):196.
Title: Calnexin, an ER stress-induced protein, is a prognostic marker and potential therapeutic target in colorectal cancer.
Author: Ryan, Deborah|Carberry, Steven|Murphy, Aine C|Lindner, Andreas U|Fay, Joanna|Hector, Suzanne|McCawley, Niamh|Bacon, Orna|Concannon, Caoimhin G|Kay, Elaine W|McNamara, Deborah A|Prehn, Jochen H M
PMID: 27369741
Journal: Mol Cell Biochem. 2016 Aug;419(1-2):29-40.
Title: Elucidation of a novel phenformin derivative on glucose-deprived stress responses in HT-29 cells.
Author: Oh-Hashi, Kentaro|Irie, Nao|Sakai, Takayuki|Okuda, Kensuke|Nagasawa, Hideko|Hirata, Yoko|Kiuchi, Kazutoshi
PMID: 27392906
Journal: Sci Rep. 2016 Jul 27;6:30406.
Title: Acetylation modification regulates GRP78 secretion in colon cancer cells.
Author: Li, Zongwei|Zhuang, Ming|Zhang, Lichao|Zheng, Xingnan|Yang, Peng|Li, Zhuoyu
PMID: 27460191
Journal: Oncol Rep. 2016 Oct;36(4):2268-74.
Title: Non-thermal gas plasma-induced endoplasmic reticulum stress mediates apoptosis in human colon cancer cells.
Author: Ruwan Kumara, Madduma Hewage Susara|Piao, Mei Jing|Kang, Kyoung Ah|Ryu, Yea Seong|Park, Jeong Eon|Shilnikova, Kristina|Jo, Jin Oh|Mok, Young Sun|Shin, Jennifer H|Park, Yeonsoo|Kim, Seong Bong|Yoo, Suk Jae|Hyun, Jin Won
PMID: 27573888
Journal: PLoS One. 2016 Sep 9;11(9):e0162448.
Title: Bifidobacteria Prevent Tunicamycin-Induced Endoplasmic Reticulum Stress and Subsequent Barrier Disruption in Human Intestinal Epithelial Caco-2 Monolayers.
Author: Akiyama, Takuya|Oishi, Kenji|Wullaert, Andy
PMID: 27611782
Journal: Oncoimmunology. 2016 Jun 29;5(7):e1149667.
Title: Immunomodulation by MYB is associated with tumor relapse in patients with early stage colorectal cancer.
Author: Millen, Rosemary|Malaterre, Jordane|Cross, Ryan S|Carpinteri, Sandra|Desai, Jayesh|Tran, Ben|Darcy, Phillip|Gibbs, Peter|Sieber, Oliver|Zeps, Nikolajs|Waring, Paul|Fox, Stephen|Pereira, Lloyd|Ramsay, Robert G
PMID: 27622014
Journal: Oncol Rep. 2016 Nov;36(5):2723-2730.
Title: Glucose-regulated protein 78 contributes to the proliferation and tumorigenesis of human colorectal carcinoma via AKT and ERK pathways.
Author: Zhou, Xuan|Xing, Xiaoming|Zhang, Shuping|Liu, Lili|Wang, Chengqin|Li, Lin|Ji, Qiuxia|Liu, Huamin
PMID: 27634156
Journal: Oncogene. 2017 Jun 15;36(24):3397-3405.
Title: Induction of endoplasmic reticulum stress by deletion of Grp78 depletes Apc mutant intestinal epithelial stem cells.
Author: van Lidth de Jeude, J F|Meijer, B J|Wielenga, M C B|Spaan, C N|Baan, B|Rosekrans, S L|Meisner, S|Shen, Y H|Lee, A S|Paton, J C|Paton, A W|Muncan, V|van den Brink, G R|Heijmans, J
PMID: 27819675
Journal: Biochem Biophys Res Commun. 2017 Jan 22;482(4):1491-1497.
Title: BRAF-mutated cells activate GCN2-mediated integrated stress response as a cytoprotective mechanism in response to vemurafenib.
Author: Nagasawa, Ikuko|Kunimasa, Kazuhiro|Tsukahara, Satomi|Tomida, Akihiro
PMID: 27965097
Journal: Oncotarget. 2017 Jun 20;8(25):40264-40275.
Title: Curcumin enhances the effects of irinotecan on colorectal cancer cells through the generation of reactive oxygen species and activation of the endoplasmic reticulum stress pathway.
Author: Huang, Yan-Feng|Zhu, Da-Jian|Chen, Xiao-Wu|Chen, Qi-Kang|Luo, Zhen-Tao|Liu, Chang-Chun|Wang, Guo-Xin|Zhang, Wei-Jie|Liao, Nv-Zhu
PMID: 28402965
Journal: Anticancer Res. 2017 Jun;37(6):2975-2984.
Title: Enhanced Susceptibility to 5-Fluorouracil in Human Colon Cancer Cells by Silencing of GRP78.
Author: Yun, Seungpil|Han, Yong-Seok|Lee, Jun Hee|Kim, Sangmin|Lee, Sang Hun
PMID: 28551635
Journal: Anticancer Res. 2017 Sep;37(9):4943-4951.
Title: GRP78 Regulates Apoptosis, Cell Survival and Proliferation in 5-Fluorouracil-resistant SNUC5 Colon Cancer Cells.
Author: Lee, Jun Hee|Yoon, Yeo Min|Lee, Sang Hun
PMID: 28870916
Journal: J Toxicol Environ Health A. 2017;80(23-24):1230-1241.
Title: Citrinin induces apoptosis in human HCT116 colon cancer cells through endoplasmic reticulum stress.
Author: Salah, Amal|Bouaziz, Chayma|Prola, Alexandre|Pires Da Silva, Julie|Bacha, Hassen|Abid-Essefi, Salwa|Lemaire, Christophe
PMID: 29165056
Journal: Oncotarget. 2017 Aug 9;8(53):91223-91237.
Title: Jolkinolide B induces apoptosis of colorectal carcinoma through ROS-ER stress-Ca(2+)-mitochondria dependent pathway.
Author: Zhang, Jing|Wang, Yang|Zhou, Ye|He, Qing-Yu
PMID: 29207638
Journal: Biochem Cell Biol. 2018 Jun;96(3):332-341.
Title: Knockdown of CEMIP suppresses proliferation and induces apoptosis in colorectal cancer cells: downregulation of GRP78 and attenuation of unfolded protein response.
Author: Liang, Guodong|Fang, Xuedong|Yang, Yubo|Song, Yan
PMID: 29024602
Journal: Mol Pharm. 2018 Jan 2;15(1):238-246.
Title: A Novel Doxorubicin Prodrug with GRP78 Recognition and Nucleus-Targeting Ability for Safe and Effective Cancer Therapy.
Author: Ding, Guo-Bin|Sun, Junqing|Yang, Peng|Li, Binchun|Gao, Ying|Li, Zhuoyu
PMID: 29207873
Journal: Cell Death Dis. 2018 Jan 26;9(2):125.
Title: The BAX/BAK-like protein BOK is a prognostic marker in colorectal cancer.
Author: Carberry, Steven|D'Orsi, Beatrice|Monsefi, Naser|Salvucci, Manuela|Bacon, Orna|Fay, Joanna|Rehm, Markus|McNamara, Deborah|Kay, Elaine W|Prehn, Jochen H M
PMID: 29374142
Journal: Int J Mol Med. 2018 Apr;41(4):1887-1898.
Title: Resistant starch prevents tumorigenesis of dimethylhydrazine-induced colon tumors via regulation of an ER stress-mediated mitochondrial apoptosis pathway.
Author: Wang, Qiuyu|Wang, Peng|Xiao, Zhigang
PMID: 29393371
Journal: Mol Clin Oncol. 2018 Jan;8(1):22-29.
Title: A phase I clinical trial of dTCApFs, a derivative of a novel human hormone peptide, for the treatment of advanced/metastatic solid tumors.
Author: Stemmer, Salomon M|Benjaminov, Ofer|Silverman, Michael H|Sandler, Uziel|Purim, Ofer|Sender, Naomi|Meir, Chen|Oren-Apoteker, Pnina|Ohana, Joel|Devary, Yoram
PMID: 29423221
Journal: Mol Cancer Ther. 2018 Jun;17(6):1280-1290.
Title: The Unfolded Protein Response: A Novel Therapeutic Target for Poor Prognostic BRAF Mutant Colorectal Cancer.
Author: Forsythe, Nicholas|Refaat, Alaa|Javadi, Arman|Khawaja, Hajrah|Weir, Jessica-Anne|Emam, Heba|Allen, Wendy L|Burkamp, Frank|Popovici, Vlad|Jithesh, Puthen V|Isella, Claudio|Labonte, Melissa J|Mills, Ian G|Johnston, Patrick G|Van Schaeybroeck, Sandra
PMID: 29483217
Journal: Oncotarget. 2018 Jan 9;9(21):15464-15479.
Title: Ajuba receptor mediates the internalization of tumor-secreted GRP78 into macrophages through different endocytosis pathways.
Author: La, Xiaoqin|Zhang, Lichao|Li, Hanqing|Li, Zhuoyu|Song, Guisheng|Yang, Peng|Yang, Yufei
PMID: 29643986
Journal: Oncol Lett. 2018 Jun;15(6):9861-9867.
Title: Suppression of GRP78 sensitizes human colorectal cancer cells to oxaliplatin by downregulation of CD24.
Author: Xi, Jingle|Chen, Yufan|Huang, Shangbin|Cui, Fei|Wang, Xinying
PMID: 29805687
Journal: Chem Biol Interact. 2018 Aug 1;291:16-28.
Title: Antiproliferative effect of p-Coumaric acid targets UPR activation by downregulating Grp78 in colon cancer.
Author: Sharma, Sharada H|Rajamanickam, Vinothkumar|Nagarajan, Sangeetha
PMID: 29879413
Journal: Oncol Lett. 2018 Sep;16(3):3901-3906.
Title: Astragaloside attenuates the progression of prostate cancer cells through endoplasmic reticulum stress pathways.
Author: Tan, Bo|Jia, Renfeng|Wang, Gang|Yang, Jinhui
PMID: 30128005
Journal: Int J Biochem Cell Biol. 2018 Oct;103:89-98.
Title: Lysosomal permeabilization and endoplasmic reticulum stress mediate the apoptotic response induced after photoactivation of a lipophilic zinc(II) phthalocyanine.
Author: Chiarante, Nicolas|Garcia Vior, Maria C|Rey, Osvaldo|Marino, Julieta|Roguin, Leonor P
PMID: 30130653
Journal: Med Sci Monit. 2018 Sep 10;24:6331-6339.
Title: Aloe-Emodin Induces Endoplasmic Reticulum Stress-Dependent Apoptosis in Colorectal Cancer Cells.
Author: Cheng, Chunsheng|Dong, Weiguo
PMID: 30199885
Journal: Sci Rep. 2018 Sep 14;8(1):13869.
Title: A combination of curcumin and oligomeric proanthocyanidins offer superior anti-tumorigenic properties in colorectal cancer.
Author: Ravindranathan, Preethi|Pasham, Divya|Balaji, Uthra|Cardenas, Jacob|Gu, Jinghua|Toden, Shusuke|Goel, Ajay
PMID: 30218018
Journal: Oncogene. 2018 Sep 19. pii: 10.1038/s41388-018-0489-4.
Title: Klotho suppresses colorectal cancer through modulation of the unfolded protein response.
Author: Arbel Rubinstein, Tammi|Shahmoon, Shiri|Zigmond, Ehud|Etan, Tal|Merenbakh-Lamin, Keren|Pasmanik-Chor, Metsada|Har-Zahav, Gil|Barshack, Iris|Vainer, Gilad W|Skalka, Nir|Rosin-Arbesfeld, Rina|Varol, Chen|Rubinek, Tami|Wolf, Ido
PMID: 30232408
Journal: FEBS J. 2018 Oct 30.
Title: 2-Deoxyglucose has distinct and cell line-specific effects on the survival of different cancer cells upon antitumor drug treatment.
Author: Maximchik, Polina|Abdrakhmanov, Alibek|Inozemtseva, Evgeniya|Tyurin-Kuzmin, Pyotr A|Zhivotovsky, Boris|Gogvadze, Vladimir
PMID: 30375744