Primary Site >> Stomach Cancer

Gene >> HSP90AA1

Journal: Int J Oncol. 1994 Dec;5(6):1347-51.
Title: Differential expression of hsp90, gelsolin and gst-pi in human gastric-carcinoma cell-lines.
Author: Moriya, S|Yanagihara, K|Fujita, H|Kuzumaki, N
PMID: 21559720
Journal: World J Gastroenterol. 1999 Jun;5(3):199-208.
Title: Down-regulation of Hsp90 could change cell cycle distribution and increase drug sensitivity of tumor cells.
Author: Liu, Xian-Ling|Xiao, Bing|Yu, Zhao-Cai|Guo, Jian-Cheng|Zhao, Qing-Chuan|Xu, Li|Shi, Yong-Quan|Fan, Dai-Ming
PMID: 11819430
Journal: Mol Cancer Ther. 2007 Mar;6(3):1123-32.
Title: Inhibition of heat shock protein 90 impairs epidermal growth factor-mediated signaling in gastric cancer cells and reduces tumor growth and vascularization in vivo.
Author: Lang, Sven A|Klein, Dagmar|Moser, Christian|Gaumann, Andreas|Glockzin, Gabriel|Dahlke, Marc H|Dietmaier, Wolfgang|Bolder, Ulrich|Schlitt, Hans J|Geissler, Edward K|Stoeltzing, Oliver
PMID: 17363505
Journal: J Natl Cancer Inst. 2007 Jun 20;99(12):949-61.
Title: Structural basis for depletion of heat shock protein 90 client proteins by deguelin.
Author: Oh, Seung Hyun|Woo, Jong Kyu|Yazici, Yasemin Dakak|Myers, Jeffrey N|Kim, Woo-Young|Jin, Quanri|Hong, Soon Sun|Park, Hyun-Ju|Suh, Young-Ger|Kim, Kyu-Won|Hong, Waun Ki|Lee, Ho-Young
PMID: 17565155
Journal: Ai Zheng. 2007 Oct;26(10):1080-4.
Title: [Screening human gastric carcinoma-associated antigens by serologic proteome analysis].
Author: Zeng, Xi|Liao, Ai-Jun|Tang, Hai-Lin|Yi, Lan|Xie, Na|Su, Qi
PMID: 17927877
Journal: Mol Cancer Ther. 2007 Nov;6(11):2868-78.
Title: Blocking heat shock protein-90 inhibits the invasive properties and hepatic growth of human colon cancer cells and improves the efficacy of oxaliplatin in p53-deficient colon cancer tumors in vivo.
Author: Moser, Christian|Lang, Sven A|Kainz, Silvia|Gaumann, Andreas|Fichtner-Feigl, Stefan|Koehl, Gudrun E|Schlitt, Hans J|Geissler, Edward K|Stoeltzing, Oliver
PMID: 18025273
Journal: Int J Cancer. 2009 Dec 15;125(12):2844-53.
Title: Identification of novel hub genes associated with liver metastasis of gastric cancer.
Author: Chang, Wenjun|Ma, Liye|Lin, Liping|Gu, Liqiang|Liu, Xiaokang|Cai, Hui|Yu, Yongwei|Tan, Xiaojie|Zhai, Yujia|Xu, Xingxing|Zhang, Minfeng|Wu, Lingling|Zhang, Hongwei|Hou, Jianguo|Wang, Hongyang|Cao, Guangwen
PMID: 19569046
Journal: OMICS. 2011 Jan-Feb;15(1-2):83-90.
Title: Characterization of phosphoproteins in gastric cancer secretome.
Author: Yan, Guang-Rong|Ding, Wen|Xu, Song-Hui|Xu, Zhen|Xiao, Chuan-Le|Yin, Xing-Feng|He, Qing-Yu
PMID: 20726782
Journal: Cancer Sci. 2011 Jul;102(7):1388-95.
Title: Antitumor activity of NVP-AUY922, a novel heat shock protein 90 inhibitor, in human gastric cancer cells is mediated through proteasomal degradation of client proteins.
Author: Lee, Kyung-Hun|Lee, Ju-Hee|Han, Sae-Won|Im, Seock-Ah|Kim, Tae-You|Oh, Do-Youn|Bang, Yung-Jue
PMID: 21453385
Journal: J Transl Med. 2011 Jan 14;9:8.
Title: Designed hybrid TPR peptide targeting Hsp90 as a novel anticancer agent.
Author: Horibe, Tomohisa|Kohno, Masayuki|Haramoto, Mari|Ohara, Koji|Kawakami, Koji
PMID: 21235734
Journal: Dig Dis Sci. 2011 Feb;56(2):323-9.
Title: Targeting PI3K/Akt/HSP90 signaling sensitizes gastric cancer cells to deoxycholate-induced apoptosis.
Author: Redlak, Maria J|Miller, Thomas A
PMID: 20585984
Journal: Cancer Sci. 2012 Feb;103(2):342-9.
Title: Preclinical antitumor activity of the novel heat shock protein 90 inhibitor CH5164840 against human epidermal growth factor receptor 2 (HER2)-overexpressing cancers.
Author: Ono, Naomi|Yamazaki, Toshikazu|Nakanishi, Yoshito|Fujii, Toshihiko|Sakata, Kiyoaki|Tachibana, Yukako|Suda, Atsushi|Hada, Kihito|Miura, Takaaki|Sato, Shigeo|Saitoh, Ryoichi|Nakano, Kohnosuke|Tsukuda, Takuo|Mio, Toshiyuki|Ishii, Nobuya|Kondoh, Osamu|Aoki, Y
PMID: 22050138
Journal: Anticancer Res. 2012 Feb;32(2):427-37.
Title: Oncogenic MST1R activity in pancreatic and gastric cancer represents a valid target of HSP90 inhibitors.
Author: Moser, Christian|Lang, Sven A|Hackl, Christina|Zhang, Hong|Lundgren, Karen|Hong, Victor|McKenzie, Andres|Weber, Bernhard|Park, Jung S|Schlitt, Hans J|Geissler, Edward K|Jung, Young D|Stoeltzing, Oliver
PMID: 22287729
Journal: Oncologist. 2012;17(5):653-62.
Title: Losses of chromosome 5q and 14q are associated with favorable clinical outcome of patients with gastric cancer.
Author: Buffart, Tineke E|Carvalho, Beatriz|van Grieken, Nicole C T|van Wieringen, Wessel N|Tijssen, Marianne|Kranenbarg, Elma Meershoek-Klein|Verheul, Henk M W|Grabsch, Heike I|Ylstra, Bauke|van de Velde, Cornelis J H|Meijer, Gerrit A
PMID: 22531355
Journal: BMC Cancer. 2013 Nov 9;13:536.
Title: Mapping the interactome of overexpressed RAF kinase inhibitor protein in a gastric cancer cell line.
Author: Gu, Huan|Zhan, Xianquan|Zhang, Guiying|Yan, Lu|Cho, William Cs|Li, Maoyu|Liu, Ting|Chen, Zhuchu
PMID: 24209905
Journal: PLoS One. 2013 Jul 11;8(7):e69098.
Title: Association between HSP90 and Her2 in gastric and gastroesophageal carcinomas.
Author: Berezowska, Sabina|Novotny, Alexander|Bauer, Karina|Feuchtinger, Annette|Slotta-Huspenina, Julia|Becker, Karen|Langer, Rupert|Walch, Axel
PMID: 23874879
Journal: PLoS One. 2013 Apr 26;8(4):e62876.
Title: High expression of heat shock protein 90 is associated with tumor aggressiveness and poor prognosis in patients with advanced gastric cancer.
Author: Wang, Jiahong|Cui, Shuzhong|Zhang, Xiangliang|Wu, Yinbing|Tang, Hongsheng
PMID: 23638161
Journal: Biochem Pharmacol. 2013 May 1;85(9):1246-56.
Title: Inhibition of gastric tumor growth by a novel Hsp90 inhibitor.
Author: Lu, Chunwan|Liu, Di|Jin, Jing|Deokar, Hemantkumar|Zhang, Yi|Buolamwini, John K|Yu, Xiaoming|Yan, Chunhong|Chen, Xiaoguang
PMID: 23415900
Journal: Mol Cancer Ther. 2013 Apr;12(4):509-19.
Title: Inhibition of HSP90 with AUY922 induces synergy in HER2-amplified trastuzumab-resistant breast and gastric cancer.
Author: Wainberg, Zev A|Anghel, Adrian|Rogers, Amy M|Desai, Amrita J|Kalous, Ondrej|Conklin, Dylan|Ayala, Raul|O'Brien, Neil A|Quadt, Cornelia|Akimov, Mikhail|Slamon, Dennis J|Finn, Richard S
PMID: 23395886
Journal: Crit Rev Oncol Hematol. 2013 Mar;85(3):350-62.
Title: Advanced HER2-positive gastric cancer: current and future targeted therapies.
Author: Pazo Cid, Roberto A|Anton, Antonio
PMID: 23021388
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2013 Feb;33(2):271-5.
Title: [Effects of HSP90 inhibitor 17-AAG on cell cycle and apoptosis of human gastric cancer cell lines SGC-7901].
Author: Chen, Meini|Xu, Jinghong|Zhao, Jumei
PMID: 23443787
Journal: Eur J Cancer. 2014 Jan;50(1):204-15.
Title: Caveolin-1 promotes gastric cancer progression by up-regulating epithelial to mesenchymal transition by crosstalk of signalling mechanisms under hypoxic condition.
Author: Kannan, Anbarasu|Krishnan, Arunkumar|Ali, Mohammed|Subramaniam, Shyama|Halagowder, Devaraj|Sivasithamparam, Niranjali Devaraj
PMID: 24070739
Journal: Bioorg Med Chem. 2014 Jan 15;22(2):892-905.
Title: Design and synthesis of 2-amino-6-(1H,3H-benzo[de]isochromen-6-yl)-1,3,5-triazines as novel Hsp90 inhibitors.
Author: Suda, Atsushi|Kawasaki, Ken-ichi|Komiyama, Susumu|Isshiki, Yoshiaki|Yoon, Dong-Oh|Kim, Sung-Jin|Na, Young-Jun|Hasegawa, Kiyoshi|Fukami, Takaaki A|Sato, Shigeo|Miura, Takaaki|Ono, Naomi|Yamazaki, Toshikazu|Saitoh, Ryoichi|Shimma, Nobuo|Shiratori, Yasuhiko|
PMID: 24369839
Journal: Oncol Rep. 2014 Dec;32(6):2429-36.
Title: Geldanamycin mediates the apoptosis of gastric carcinoma cells through inhibition of EphA2 protein expression.
Author: Wang, Da-Hu|Zhang, Yu-Jun|Zhang, San-Bing|Liu, Hui|Liu, Liang|Liu, Feng-Ling|Zuo, Jing
PMID: 25310629
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2014 Oct;17(10):1031-5.
Title: [Influence of 17AAG on proliferation and invasion of gastric cancer cell and its mechanism].
Author: Cui, Yuehong|Yu, Yiyi|Liu, Tianshu|Xie, Qian|Wu, Weizhong|Liu, Kangda
PMID: 25341914
Journal: Cell Commun Signal. 2014 Nov 15;12:69.
Title: An increase in integrin-linked kinase non-canonically confers NF-kappaB-mediated growth advantages to gastric cancer cells by activating ERK1/2.
Author: Tseng, Po-Chun|Chen, Chia-Ling|Shan, Yan-Shen|Chang, Wen-Teng|Liu, Hsiao-Sheng|Hong, Tse-Ming|Hsieh, Chia-Yuan|Lin, Sheng-Hsiang|Lin, Chiou-Feng
PMID: 25398317
Journal: Cell Physiol Biochem. 2015;37(6):2339-54.
Title: Mitochondrial Proteomics Approach Reveals Voltage-Dependent Anion Channel 1 (VDAC1) as a Potential Biomarker of Gastric Cancer.
Author: Gao, Wen|Xua, Jing|Wang, Fuqiang|Zhang, Long|Peng, Rui|Zhu, Yunxia|Tang, Qiyun|Wu, Jindao
PMID: 26646027
Journal: Oncol Lett. 2015 Dec;10(6):3732-3736.
Title: Geldanamycin induces apoptosis in human gastric carcinomas by affecting multiple oncogenic kinases that have synergic effects with TNF-related apoptosis-inducing ligand.
Author: Chen, Hui|Li, Liang-Qing|Pan, Dun
PMID: 26788199
Journal: J Biomed Sci. 2015 Jun 24;22:44.
Title: N-terminal functional domain of Gasdermin A3 regulates mitochondrial homeostasis via mitochondrial targeting.
Author: Lin, Pei-Hsuan|Lin, Hsien-Yi|Kuo, Cheng-Chin|Yang, Liang-Tung
PMID: 26100518
Journal: Cell Death Dis. 2015 Jan 15;6:e1595.
Title: Targeting heat-shock protein 90 with ganetespib for molecularly targeted therapy of gastric cancer.
Author: Liu, H|Lu, J|Hua, Y|Zhang, P|Liang, Z|Ruan, L|Lian, C|Shi, H|Chen, K|Tu, Z
PMID: 25590805
Journal: Biochem J. 2016 Jun 15;473(12):1703-18.
Title: Septin oligomerization regulates persistent expression of ErbB2/HER2 in gastric cancer cells.
Author: Marcus, Elizabeth A|Tokhtaeva, Elmira|Turdikulova, Shahlo|Capri, Joseph|Whitelegge, Julian P|Scott, David R|Sachs, George|Berditchevski, Fedor|Vagin, Olga
PMID: 27048593
Journal: Asian Pac J Cancer Prev. 2016;17(8):3929-37.
Title: Heat Shock Protein Association with Clinico-Pathological Characteristics of Gastric Cancer in Jordan : HSP70 is Predictive of Poor Prognosis.
Author: Bodoor, Khaldon|Jalboush, Sara Abu|Matalka, Ismail|Abu-Sheikha, Aya|Waq, Rofieda Al|Ebwaini, Hanadi|Abu-Awad, Aymen|Fayyad, Luma|Al-Arjat, Jamal|Haddad, Yazan
PMID: 27644641
Journal: Zhonghua Zhong Liu Za Zhi. 2017 Feb 23;39(2):109-114.
Title: [Preparation of chaperone-antigen peptide vaccine derived from human gastric cancer stem cells and its immune function].
Author: Jiang, Y Q|Guo, Q M|Xu, X P|Liang, J C|He, Y Y|An, S H|Su, F|Li, C Y|Huang, C X
PMID: 28219205
Journal: Int J Oncol. 2017 Sep;51(3):967-974.
Title: Ganetespib induces G2/M cell cycle arrest and apoptosis in gastric cancer cells through targeting of receptor tyrosine kinase signaling.
Author: Lee, Harry|Saini, Nipun|Parris, Amanda B|Zhao, Ming|Yang, Xiaohe
PMID: 28713919
Journal: Oncotarget. 2017 Apr 10;8(34):56473-56489.
Title: HSP90 inhibitor 17-DMAG exerts anticancer effects against gastric cancer cells principally by altering oxidant-antioxidant balance.
Author: Kim, Jeong Goo|Lee, Sang Chul|Kim, Ok-Hee|Kim, Kee-Hwan|Song, Kyo Young|Lee, Sang Kuon|Choi, Byung Jo|Jeong, Wonjun|Kim, Say-June
PMID: 28915605
Journal: Oncogene. 2018 May 10. pii: 10.1038/s41388-018-0266-4.
Title: GALNT5 uaRNA promotes gastric cancer progression through its interaction with HSP90.
Author: Guo, Hui|Zhao, Lianmei|Shi, Bianhua|Bao, Jiayu|Zheng, Dexian|Zhou, Baoguo|Shi, Juan
PMID: 29743591
Journal: J Gastrointest Oncol. 2018 Apr;9(2):303-310.
Title: An assessment of candidate genes to assist prognosis in gastric cancer.
Author: McFarlane, Michael|Brettschneider, Julia|Gelsthorpe, Adrian|James, Sean|Snead, David|Gopalakrishnan, Kishore|Mehenna, Hisham|Jankowski, Janusz|Arasaradnam, Ramesh|Nwokolo, Chuka
PMID: 29755769
Journal: Cell Physiol Biochem. 2018;47(2):879-892.
Title: HSP70/HSP90-Organizing Protein Contributes to Gastric Cancer Progression in an Autocrine Fashion and Predicts Poor Survival in Gastric Cancer.
Author: Zhai, Ertao|Liang, Wei|Lin, Yi|Huang, Linlin|He, Xin|Cai, Shirong|Chen, Jianhui|Zhang, Ning|Li, Jiali|Zhang, Qiuyang|He, Yulong|Zeng, Zhirong|Chen, Minhu|Xu, Lixia|Peng, Sui
PMID: 29843139
Journal: Oncol Lett. 2018 Jun;15(6):9385-9391.
Title: Clinical significance of heat shock proteins in gastric cancer following hyperthermia stress: Indications for hyperthermic intraperitoneal chemoperfusion therapy.
Author: Tu, Yinuo|Tian, Yunhong|Wu, Yinbing|Cui, Shuzhong
PMID: 29946371
Journal: Int J Biol Sci. 2018 Jun 22;14(9):1122-1132.
Title: KDM5B demethylates H3K4 to recruit XRCC1 and promote chemoresistance.
Author: Xu, Wenxia|Zhou, Bingluo|Zhao, Xiaoya|Zhu, Liyuan|Xu, Jinye|Jiang, Zhinong|Chen, Dingwei|Wei, Qi|Han, Mengjiao|Feng, Lifeng|Wang, Shouyu|Wang, Xian|Zhou, Jianwei|Jin, Hongchuan
PMID: 29989047