Primary Site >> Stomach Cancer
Gene >> HSP90AA1
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Ref: Differential expression of hsp90, gelsolin and gst-pi in human gastric-carcinoma cell-lines. PMID: 21559720 |
Ref: Down-regulation of Hsp90 could change cell cycle distribution and increase drug sensitivity of tumor cells. PMID: 11819430 |
Ref: Inhibition of heat shock protein 90 impairs epidermal growth factor-mediated signaling in gastric cancer cells and reduces tumor growth and vascularization in vivo. PMID: 17363505 Ref: Structural basis for depletion of heat shock protein 90 client proteins by deguelin. PMID: 17565155 Ref: [Screening human gastric carcinoma-associated antigens by serologic proteome analysis]. PMID: 17927877 Ref: Blocking heat shock protein-90 inhibits the invasive properties and hepatic growth of human colon cancer cells and improves the efficacy of oxaliplatin in p53-deficient colon cancer tumors in vivo. PMID: 18025273 |
Ref: Identification of novel hub genes associated with liver metastasis of gastric cancer. PMID: 19569046 |
Ref: Targeting PI3K/Akt/HSP90 signaling sensitizes gastric cancer cells to deoxycholate-induced apoptosis. PMID: 20585984 Ref: Characterization of phosphoproteins in gastric cancer secretome. PMID: 20726782 Ref: Designed hybrid TPR peptide targeting Hsp90 as a novel anticancer agent. PMID: 21235734 Ref: Antitumor activity of NVP-AUY922, a novel heat shock protein 90 inhibitor, in human gastric cancer cells is mediated through proteasomal degradation of client proteins. PMID: 21453385 |
Ref: Preclinical antitumor activity of the novel heat shock protein 90 inhibitor CH5164840 against human epidermal growth factor receptor 2 (HER2)-overexpressing cancers. PMID: 22050138 Ref: Oncogenic MST1R activity in pancreatic and gastric cancer represents a valid target of HSP90 inhibitors. PMID: 22287729 Ref: Losses of chromosome 5q and 14q are associated with favorable clinical outcome of patients with gastric cancer. PMID: 22531355 |
Ref: Advanced HER2-positive gastric cancer: current and future targeted therapies. PMID: 23021388 Ref: Inhibition of HSP90 with AUY922 induces synergy in HER2-amplified trastuzumab-resistant breast and gastric cancer. PMID: 23395886 Ref: Inhibition of gastric tumor growth by a novel Hsp90 inhibitor. PMID: 23415900 Ref: [Effects of HSP90 inhibitor 17-AAG on cell cycle and apoptosis of human gastric cancer cell lines SGC-7901]. PMID: 23443787 Ref: High expression of heat shock protein 90 is associated with tumor aggressiveness and poor prognosis in patients with advanced gastric cancer. PMID: 23638161 Ref: Association between HSP90 and Her2 in gastric and gastroesophageal carcinomas. PMID: 23874879 Ref: Mapping the interactome of overexpressed RAF kinase inhibitor protein in a gastric cancer cell line. PMID: 24209905 |
Ref: Caveolin-1 promotes gastric cancer progression by up-regulating epithelial to mesenchymal transition by crosstalk of signalling mechanisms under hypoxic condition. PMID: 24070739 Ref: Design and synthesis of 2-amino-6-(1H,3H-benzo[de]isochromen-6-yl)-1,3,5-triazines as novel Hsp90 inhibitors. PMID: 24369839 Ref: Geldanamycin mediates the apoptosis of gastric carcinoma cells through inhibition of EphA2 protein expression. PMID: 25310629 Ref: [Influence of 17AAG on proliferation and invasion of gastric cancer cell and its mechanism]. PMID: 25341914 Ref: An increase in integrin-linked kinase non-canonically confers NF-kappaB-mediated growth advantages to gastric cancer cells by activating ERK1/2. PMID: 25398317 |
Ref: Targeting heat-shock protein 90 with ganetespib for molecularly targeted therapy of gastric cancer. PMID: 25590805 Ref: N-terminal functional domain of Gasdermin A3 regulates mitochondrial homeostasis via mitochondrial targeting. PMID: 26100518 Ref: Mitochondrial Proteomics Approach Reveals Voltage-Dependent Anion Channel 1 (VDAC1) as a Potential Biomarker of Gastric Cancer. PMID: 26646027 Ref: Geldanamycin induces apoptosis in human gastric carcinomas by affecting multiple oncogenic kinases that have synergic effects with TNF-related apoptosis-inducing ligand. PMID: 26788199 |
Ref: Septin oligomerization regulates persistent expression of ErbB2/HER2 in gastric cancer cells. PMID: 27048593 Ref: Heat Shock Protein Association with Clinico-Pathological Characteristics of Gastric Cancer in Jordan : HSP70 is Predictive of Poor Prognosis. PMID: 27644641 |
Ref: [Preparation of chaperone-antigen peptide vaccine derived from human gastric cancer stem cells and its immune function]. PMID: 28219205 Ref: Ganetespib induces G2/M cell cycle arrest and apoptosis in gastric cancer cells through targeting of receptor tyrosine kinase signaling. PMID: 28713919 Ref: HSP90 inhibitor 17-DMAG exerts anticancer effects against gastric cancer cells principally by altering oxidant-antioxidant balance. PMID: 28915605 |
Ref: GALNT5 uaRNA promotes gastric cancer progression through its interaction with HSP90. PMID: 29743591 Ref: An assessment of candidate genes to assist prognosis in gastric cancer. PMID: 29755769 Ref: HSP70/HSP90-Organizing Protein Contributes to Gastric Cancer Progression in an Autocrine Fashion and Predicts Poor Survival in Gastric Cancer. PMID: 29843139 Ref: Clinical significance of heat shock proteins in gastric cancer following hyperthermia stress: Indications for hyperthermic intraperitoneal chemoperfusion therapy. PMID: 29946371 Ref: KDM5B demethylates H3K4 to recruit XRCC1 and promote chemoresistance. PMID: 29989047 |