Literatures

Primary Site >> Colorectal Cancer

Gene >> HSP90AA1

1.
Journal:	Surg Oncol. 1995 Aug;4(4):197-203.
Title:	Heat shock proteins are differentially expressed in human gastrointestinal cancers.
Author:	Ehrenfried, J A\|Herron, B E\|Townsend, C M Jr\|Evers, B M
PMID:	8528482

2.
Journal:	Int J Cancer. 1996 Sep 17;67(6):800-7.
Title:	Heat-shock protein expression in cisplatin-sensitive and -resistant human tumor cells.
Author:	Hettinga, J V\|Lemstra, W\|Meijer, C\|Los, G\|de Vries, E G\|Konings, A W\|Kampinga, H H
PMID:	8824551

3.
Journal:	Anticancer Drugs. 1996 Nov;7(8):838-45.
Title:	Increase of P-glycoprotein-mediated drug resistance by hsp 90 beta.
Author:	Bertram, J\|Palfner, K\|Hiddemann, W\|Kneba, M
PMID:	8991187

4.
Journal:	Cancer Res. 1999 Jun 15;59(12):2931-8.
Title:	KF25706, a novel oxime derivative of radicicol, exhibits in vivo antitumor activity via selective depletion of Hsp90 binding signaling molecules.
Author:	Soga, S\|Neckers, L M\|Schulte, T W\|Shiotsu, Y\|Akasaka, K\|Narumi, H\|Agatsuma, T\|Ikuina, Y\|Murakata, C\|Tamaoki, T\|Akinaga, S
PMID:	10383157

5.
Journal:	J Natl Cancer Inst. 1999 Nov 17;91(22):1940-9.
Title:	DT-Diaphorase expression and tumor cell sensitivity to 17-allylamino, 17-demethoxygeldanamycin, an inhibitor of heat shock protein 90.
Author:	Kelland, L R\|Sharp, S Y\|Rogers, P M\|Myers, T G\|Workman, P
PMID:	10564678

6.
Journal:	Eur J Cancer. 1999 Nov;35(12):1735-42.
Title:	Suppressive subtractive hybridisation reveals differential expression of serglycin, sorcin, bone marrow proteoglycan and prostate-tumour-inducing gene I (PTI-1) in drug-resistant and sensitive tumour cell lines of haematopoetic origin.
Author:	Beyer-Sehlmeyer, G\|Hiddemann, W\|Wormann, B\|Bertram, J
PMID:	10674022

7.
Journal:	Oncogene. 2000 Aug 24;19(36):4125-33.
Title:	Gene expression profiling of human colon cancer cells following inhibition of signal transduction by 17-allylamino-17-demethoxygeldanamycin, an inhibitor of the hsp90 molecular chaperone.
Author:	Clarke, P A\|Hostein, I\|Banerji, U\|Stefano, F D\|Maloney, A\|Walton, M\|Judson, I\|Workman, P
PMID:	10962573

8.
Journal:	Ann N Y Acad Sci. 2000;926:1-12.
Title:	Programmed cell death (PCD). Apoptosis, autophagic PCD, or others?
Author:	Bursch, W\|Ellinger, A\|Gerner, C\|Frohwein, U\|Schulte-Hermann, R
PMID:	11193023

9.
Journal:	Cancer Res. 2001 May 15;61(10):4003-9.
Title:	Inhibition of signal transduction by the Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin results in cytostasis and apoptosis.
Author:	Hostein, I\|Robertson, D\|DiStefano, F\|Workman, P\|Clarke, P A
PMID:	11358818

10.
Journal:	Br J Cancer. 2002 Jul 29;87(3):339-43.
Title:	Identification of heat shock protein 90 and other proteins as tumour antigens by serological screening of an ovarian carcinoma expression library.
Author:	Luo, L-Y\|Herrera, I\|Soosaipillai, A\|Diamandis, E P
PMID:	12177805

11.
Journal:	Br J Cancer. 2002 Sep 23;87(7):783-9.
Title:	Use of radiolabelled choline as a pharmacodynamic marker for the signal transduction inhibitor geldanamycin.
Author:	Liu, D\|Hutchinson, O C\|Osman, S\|Price, P\|Workman, P\|Aboagye, E O
PMID:	12232764

12.
Journal:	Exp Cell Res. 2002 Dec 10;281(2):175-81.
Title:	Heat shock protects HCT116 and H460 cells from TRAIL-induced apoptosis.
Author:	Ozoren, Nesrin\|El-Deiry, Wafik
PMID:	12460647

13.
Journal:	FEBS Lett. 2003 Mar 13;538(1-3):19-24.
Title:	Human colon cancer cells differ in their sensitivity to curcumin-induced apoptosis and heat shock protects them by inhibiting the release of apoptosis-inducing factor and caspases.
Author:	Rashmi, R\|Santhosh Kumar, T R\|Karunagaran, D
PMID:	12633846

14.
Journal:	J Nutr Biochem. 2003 Apr;14(4):227-31.
Title:	Effect of selenium-enriched broccoli diet on differential gene expression in min mouse liver(1,2).
Author:	Zeng, Huawei\|Davis, Cindy D\|Finley, John W
PMID:	12770647

15.
Journal:	J Natl Cancer Inst. 2003 Nov 5;95(21):1624-33.
Title:	Magnetic resonance spectroscopic pharmacodynamic markers of the heat shock protein 90 inhibitor 17-allylamino,17-demethoxygeldanamycin (17AAG) in human colon cancer models.
Author:	Chung, Yuen-Li\|Troy, Helen\|Banerji, Udai\|Jackson, Laura E\|Walton, Mike I\|Stubbs, Marion\|Griffiths, John R\|Judson, Ian R\|Leach, Martin O\|Workman, Paul\|Ronen, Sabrina M
PMID:	14600095

16.
Journal:	Mol Pharmacol. 2004 Jan;65(1):235-43.
Title:	Quantitative effects on c-Jun N-terminal protein kinase signaling determine synergistic interaction of cisplatin and 17-allylamino-17-demethoxygeldanamycin in colon cancer cell lines.
Author:	Vasilevskaya, Irina A\|Rakitina, Tatiana V\|O'Dwyer, Peter J
PMID:	14722256

17.
Journal:	J Biol Chem. 2004 May 21;279(21):22483-9. Epub 2004 Mar 5.
Title:	Hsp90-binding immunophilins link p53 to dynein during p53 transport to the nucleus.
Author:	Galigniana, Mario D\|Harrell, Jennifer M\|O'Hagen, Heather M\|Ljungman, Mats\|Pratt, William B
PMID:	15004035

18.
Journal:	Ann Surg Oncol. 2004 Apr;11(4):399-406.
Title:	Heat shock protein 70 is induced in mouse human colon tumor xenografts after sublethal radiofrequency ablation.
Author:	Yang, Weng-Lang\|Nair, Deepak G\|Makizumi, Ryouji\|Gallos, George\|Ye, Xuemei\|Sharma, Rohit R\|Ravikumar, T S
PMID:	15070600

19.
Journal:	Nat Cell Biol. 2004 Aug;6(8):731-40. Epub 2004 Jul 4.
Title:	SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells.
Author:	Hamamoto, Ryuji\|Furukawa, Yoichi\|Morita, Masashi\|Iimura, Yuko\|Silva, Fabio Pittella\|Li, Meihua\|Yagyu, Ryuichiro\|Nakamura, Yusuke
PMID:	15235609

20.
Journal:	World J Gastroenterol. 2004 Nov 1;10(21):3122-6.
Title:	Induction of HSF1 expression is associated with sporadic colorectal cancer.
Author:	Cen, Hui\|Zheng, Shu\|Fang, Yong-Ming\|Tang, Xiao-Ping\|Dong, Qi
PMID:	15457556

21.
Journal:	J Biol Chem. 2005 Mar 11;280(10):8875-83. Epub 2005 Jan 4.
Title:	Hyaluronan constitutively regulates ErbB2 phosphorylation and signaling complex formation in carcinoma cells.
Author:	Ghatak, Shibnath\|Misra, Suniti\|Toole, Bryan P
PMID:	15632176

22.
Journal:	Oncogene. 2005 Apr 21;24(18):3011-9.
Title:	Combined inhibition of extracellular signal-regulated kinases and HSP90 sensitizes human colon carcinoma cells to ionizing radiation.
Author:	Kobayashi, Shinichiro\|Nantz, Regan\|Kitamura, Tetsuya\|Higashikubo, Ryuji\|Horikoshi, Nobuo
PMID:	15735687

23.
Journal:	Cancer Chemother Pharmacol. 2005 Aug;56(2):126-37.
Title:	Comparison of 17-dimethylaminoethylamino-17-demethoxy-geldanamycin (17DMAG) and 17-allylamino-17-demethoxygeldanamycin (17AAG) in vitro: effects on Hsp90 and client proteins in melanoma models.
Author:	Smith, Victoria\|Sausville, Edward A\|Camalier, Richard F\|Fiebig, Heinz-Herbert\|Burger, Angelika M
PMID:	15841378

24.
Journal:	Biochem Pharmacol. 2005 Aug 15;70(4):580-9.
Title:	17-Allylamino-17-demethoxygeldanamycin overcomes TRAIL resistance in colon cancer cell lines.
Author:	Vasilevskaya, Irina A\|O'Dwyer, Peter J
PMID:	15993848

25.
Journal:	Cancer Res. 2006 Apr 15;66(8):4191-7.
Title:	Heat shock protein 70 neutralization exerts potent antitumor effects in animal models of colon cancer and melanoma.
Author:	Schmitt, Elise\|Maingret, Loic\|Puig, Pierre-Emmanuel\|Rerole, Anne-Laure\|Ghiringhelli, Francois\|Hammann, Arlette\|Solary, Eric\|Kroemer, Guido\|Garrido, Carmen
PMID:	16618741

26.
Journal:	J Med Chem. 2006 Oct 19;49(21):6290-7.
Title:	Enzyme specific activation of benzoquinone ansamycin prodrugs using HuCC49DeltaCH2-beta-galactosidase conjugates.
Author:	Fang, Lanyan\|Battisti, Robert F\|Cheng, Hao\|Reigan, Philip\|Xin, Yan\|Shen, Jie\|Ross, David\|Chan, Kenneth K\|Martin, Edward W Jr\|Wang, Peng George\|Sun, Duxin
PMID:	17034135

27.
Journal:	Chem Biol. 2006 Nov;13(11):1203-15.
Title:	Inhibition of Hsp90 with synthetic macrolactones: synthesis and structural and biological evaluation of ring and conformational analogs of radicicol.
Author:	Proisy, Nicolas\|Sharp, Swee Y\|Boxall, Kathy\|Connelly, Stephen\|Roe, S Mark\|Prodromou, Chrisostomos\|Slawin, Alexandra M Z\|Pearl, Laurence H\|Workman, Paul\|Moody, Christopher J
PMID:	17114002

28.
Journal:	Carcinogenesis. 2007 Jan;28(1):71-80. Epub 2006 Jun 14.
Title:	Sustained activation of protein kinase C downregulates nuclear factor-kappaB signaling by dissociation of IKK-gamma and Hsp90 complex in human colonic epithelial cells.
Author:	Park, Kyeong Ah\|Byun, Hee Sun\|Won, Minho\|Yang, Keum-Jin\|Shin, Sanghee\|Piao, Longzhen\|Kim, Jin Man\|Yoon, Wan-Hee\|Junn, Eunsung\|Park, Jongsun\|Seok, Jeong Ho\|Hur, Gang Min
PMID:	16774932

29.
Journal:	Biochem Pharmacol. 2007 Jun 1;73(11):1715-26. Epub 2007 Feb 4.
Title:	Inhibition of G1/S transition potentiates oxaliplatin-induced cell death in colon cancer cell lines.
Author:	Rakitina, Tatiana V\|Vasilevskaya, Irina A\|O'Dwyer, Peter J
PMID:	17343830

30.
Journal:	Mol Cancer Ther. 2007 Apr;6(4):1198-211.
Title:	Inhibition of the heat shock protein 90 molecular chaperone in vitro and in vivo by novel, synthetic, potent resorcinylic pyrazole/isoxazole amide analogues.
Author:	Sharp, Swee Y\|Prodromou, Chrisostomos\|Boxall, Kathy\|Powers, Marissa V\|Holmes, Joanna L\|Box, Gary\|Matthews, Thomas P\|Cheung, Kwai-Ming J\|Kalusa, Andrew\|James, Karen\|Hayes, Angela\|Hardcastle, Anthea\|Dymock, Brian\|Brough, Paul A\|Barril, Xavier\|Cansfield, Jul
PMID:	17431102

31.
Journal:	Cancer Lett. 2007 Oct 28;256(2):207-17. Epub 2007 Jul 20.
Title:	Bone morphogenetic protein-4 inhibits heat-induced apoptosis by modulating MAPK pathways in human colon cancer HCT116 cells.
Author:	Deng, Haiyun\|Ravikumar, T S\|Yang, Weng-Lang
PMID:	17640799

32.
Journal:	Proteomics. 2007 Nov;7(22):4082-9.
Title:	Proteome analysis of metastatic colorectal cancer cells recognized by the lectin Helix pomatia agglutinin (HPA).
Author:	Saint-Guirons, Julien\|Zeqiraj, Elton\|Schumacher, Udo\|Greenwell, Pamela\|Dwek, Miriam
PMID:	17994629

33.
Journal:	Br J Cancer. 2007 Nov 19;97(10):1344-53.
Title:	R306465 is a novel potent inhibitor of class I histone deacetylases with broad-spectrum antitumoral activity against solid and haematological malignancies.
Author:	Arts, J\|Angibaud, P\|Marien, A\|Floren, W\|Janssens, B\|King, P\|van Dun, J\|Janssen, L\|Geerts, T\|Tuman, R W\|Johnson, D L\|Andries, L\|Jung, M\|Janicot, M\|van Emelen, K
PMID:	18000499

34.
Journal:	Mol Cancer Ther. 2007 Nov;6(11):2868-78.
Title:	Blocking heat shock protein-90 inhibits the invasive properties and hepatic growth of human colon cancer cells and improves the efficacy of oxaliplatin in p53-deficient colon cancer tumors in vivo.
Author:	Moser, Christian\|Lang, Sven A\|Kainz, Silvia\|Gaumann, Andreas\|Fichtner-Feigl, Stefan\|Koehl, Gudrun E\|Schlitt, Hans J\|Geissler, Edward K\|Stoeltzing, Oliver
PMID:	18025273

35.
Journal:	Curr Med Chem. 2007;14(29):3122-38.
Title:	Drug-mediated targeted disruption of multiple protein activities through functional inhibition of the Hsp90 chaperone complex.
Author:	Stravopodis, Dimitrios J\|Margaritis, Lukas H\|Voutsinas, Gerassimos E
PMID:	18220746

36.
Journal:	J Med Chem. 2008 Jan 24;51(2):196-218.
Title:	4,5-diarylisoxazole Hsp90 chaperone inhibitors: potential therapeutic agents for the treatment of cancer.
Author:	Brough, Paul A\|Aherne, Wynne\|Barril, Xavier\|Borgognoni, Jenifer\|Boxall, Kathy\|Cansfield, Julie E\|Cheung, Kwai-Ming J\|Collins, Ian\|Davies, Nicholas G M\|Drysdale, Martin J\|Dymock, Brian\|Eccles, Suzanne A\|Finch, Harry\|Fink, Alexandra\|Hayes, Angela\|Howes, Rob
PMID:	18020435

37.
Journal:	J Org Chem. 2008 Jan 18;73(2):369-73.
Title:	Synthesis and evaluation of derrubone and select analogues.
Author:	Hastings, Jedidiah M\|Hadden, M Kyle\|Blagg, Brian S J
PMID:	18154304

38.
Journal:	Int J Oncol. 2008 Jun;32(6):1169-78.
Title:	Molecular characterization of hsp90 isoforms in colorectal cancer cells and its association with tumour progression.
Author:	Milicevic, Z\|Bogojevic, D\|Mihailovic, M\|Petrovic, M\|Krivokapic, Z
PMID:	18497978

39.
Journal:	Oncogene. 2008 Sep 18;27(42):5567-77.
Title:	Geldanamycin promotes premature mitotic entry and micronucleation in irradiated p53/p21 deficient colon carcinoma cells.
Author:	Moran, D M\|Gawlak, G\|Jayaprakash, M S\|Mayar, S\|Maki, C G
PMID:	18504430

40.
Journal:	Cancer Res. 2008 Aug 1;68(15):6324-30.
Title:	Oxidative stress plays a critical role in inactivating mutant BRAF by geldanamycin derivatives.
Author:	Fukuyo, Yayoi\|Inoue, Masahiro\|Nakajima, Takuma\|Higashikubo, Ryuji\|Horikoshi, Nobuko T\|Hunt, Clayton\|Usheva, Anny\|Freeman, Michael L\|Horikoshi, Nobuo
PMID:	18676857

41.
Journal:	Mol Pharmacol. 2009 Jan;75(1):124-33.
Title:	90-kDa heat shock protein inhibition abrogates the topoisomerase I poison-induced G2/M checkpoint in p53-null tumor cells by depleting Chk1 and Wee1.
Author:	Tse, Archie N\|Sheikh, Tahir N\|Alan, Ho\|Chou, Ting-Chao\|Schwartz, Gary K
PMID:	18820127

42.
Journal:	Oncogene. 2009 Jan 15;28(2):157-69.
Title:	Silencing the cochaperone CDC37 destabilizes kinase clients and sensitizes cancer cells to HSP90 inhibitors.
Author:	Smith, J R\|Clarke, P A\|de Billy, E\|Workman, P
PMID:	18931700

43.
Journal:	Biochem Pharmacol. 2009 Jan 15;77(2):151-8.
Title:	Indirect participation of Hsp90 in the regulation of the cyclin E turnover.
Author:	Bedin, Monique\|Catelli, Maria-Grazia\|Cabanie, Lucien\|Gaben, Anne-Marie\|Mester, Jan
PMID:	18977205

44.
Journal:	Biochem Biophys Res Commun. 2009 Feb 6;379(2):514-8.
Title:	Tosylcyclonovobiocic acids promote cleavage of the hsp90-associated cochaperone p23.
Author:	Radanyi, Christine\|Le Bras, Gaelle\|Bouclier, Celine\|Messaoudi, Samir\|Peyrat, Jean-Francois\|Brion, Jean-Daniel\|Alami, Mouad\|Renoir, Jack-Michel
PMID:	19118525

45.
Journal:	Nucl Med Biol. 2009 Apr;36(3):335-42.
Title:	Evaluation of the Hsp90 inhibitor NVP-AUY922 in multicellular tumour spheroids with respect to effects on growth and PET tracer uptake.
Author:	Monazzam, Azita\|Razifar, Pasha\|Ide, Susan\|Rugaard Jensen, Michael\|Josephsson, Raymond\|Blomqvist, Carl\|Langstrom, Bengt\|Bergstrom, Mats
PMID:	19324279

46.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2009 Jul;12(4):346-9.
Title:	[Association between expressions of HSP70, HSP90 and efficacy of chemotherapy in colorectal cancer patients with unresectable liver metastasis].
Author:	Chen, Chao-wu\|Huang, Zhong-cheng\|Liu, Yun\|Yuan, Zhi-jun\|Ning, Guo-qing\|Tan, Li-xin
PMID:	19598015

47.
Journal:	Cancer Lett. 2010 Apr 1;290(1):24-35.
Title:	Geldanamycin and its anti-cancer activities.
Author:	Fukuyo, Yayoi\|Hunt, Clayton R\|Horikoshi, Nobuo
PMID:	19850405

48.
Journal:	Cancer Chemother Pharmacol. 2010 Aug;66(3):535-45.
Title:	A novel, small molecule inhibitor of Hsc70/Hsp70 potentiates Hsp90 inhibitor induced apoptosis in HCT116 colon carcinoma cells.
Author:	Massey, Andrew J\|Williamson, Douglas S\|Browne, Helen\|Murray, James B\|Dokurno, Pawel\|Shaw, Terry\|Macias, Alba T\|Daniels, Zoe\|Geoffroy, Stephanie\|Dopson, Melanie\|Lavan, Paul\|Matassova, Natalia\|Francis, Geraint L\|Graham, Christopher J\|Parsons, Rachel\|Wang, Y
PMID:	20012863

49.
Journal:	J Biol Chem. 2010 Jun 25;285(26):19821-32.
Title:	Stromal hyaluronan interaction with epithelial CD44 variants promotes prostate cancer invasiveness by augmenting expression and function of hepatocyte growth factor and androgen receptor.
Author:	Ghatak, Shibnath\|Hascall, Vincent C\|Markwald, Roger R\|Misra, Suniti
PMID:	20200161

50.
Journal:	Cancer Invest. 2010 Jul;28(6):635-41.
Title:	Geldanamycin-induced PCNA degradation in isolated Hsp90 complex from cancer cells.
Author:	Wang, Xing\|Heuvelman, Deborah M\|Carroll, James A\|Dufield, Dawn R\|Masferrer, Jaime L
PMID:	20394503

51.
Journal:	Clin Cancer Res. 2010 Jul 15;16(14):3795-804.
Title:	Safety, efficacy, pharmacokinetics, and pharmacodynamics of the combination of sorafenib and tanespimycin.
Author:	Vaishampayan, Ulka N\|Burger, Angelika M\|Sausville, Edward A\|Heilbrun, Lance K\|Li, Jing\|Horiba, M Naomi\|Egorin, Merrill J\|Ivy, Percy\|Pacey, Simon\|Lorusso, Patricia M
PMID:	20525756

52.
Journal:	Cell Stress Chaperones. 2010 Nov;15(6):1003-11.
Title:	Increased expression of co-chaperone HOP with HSP90 and HSC70 and complex formation in human colonic carcinoma.
Author:	Kubota, Hiroshi\|Yamamoto, Soh\|Itoh, Eri\|Abe, Yuki\|Nakamura, Asami\|Izumi, Yukina\|Okada, Hirotaka\|Iida, Masatake\|Nanjo, Hiroshi\|Itoh, Hideaki\|Yamamoto, Yuzo
PMID:	20617406

53.
Journal:	Int J Oncol. 2010 Sep;37(3):583-93.
Title:	Induction of HITS, a newly identified family with sequence similarity 107 protein (FAM107B), in cancer cells by heat shock stimulation.
Author:	Nakajima, Hideo\|Ishigaki, Yasuhito\|Xia, Qi-Sheng\|Ikeda, Takayuki\|Yoshitake, Yoshino\|Yonekura, Hideto\|Nojima, Takayuki\|Tanaka, Takuji\|Umehara, Hisanori\|Tomosugi, Naohisa\|Takata, Takanobu\|Shimasaki, Takeo\|Nakaya, Naoki\|Sato, Itaru\|Kawakami, Kazuyuki\|Koizumi
PMID:	20664927

54.
Journal:	Bioorg Med Chem. 2010 Sep 15;18(18):6822-56.
Title:	Design and synthesis of Hsp90 inhibitors: exploring the SAR of Sansalvamide A derivatives.
Author:	Sellers, Robert P\|Alexander, Leslie D\|Johnson, Victoria A\|Lin, Chun-Chieh\|Savage, Jeremiah\|Corral, Ricardo\|Moss, Jason\|Slugocki, Tim S\|Singh, Erinprit K\|Davis, Melinda R\|Ravula, Suchitra\|Spicer, Jamie E\|Oelrich, Jenna L\|Thornquist, Andrea\|Pan, Chung-Mao\|M
PMID:	20708938

55.
Journal:	Cell Stress Chaperones. 2010 Nov;15(6):913-27.
Title:	A cell-based screen for inhibitors of protein folding and degradation.
Author:	Boschelli, Frank\|Golas, Jennifer M\|Petersen, Roseann\|Lau, Vincent\|Chen, Lei\|Tkach, Diane\|Zhao, Qiang\|Fruhling, Dave S\|Liu, Hao\|Nam, Chaneun\|Arndt, Kim T
PMID:	20717760

56.
Journal:	J Mol Med (Berl). 2010 Dec;88(12):1243-53.
Title:	Celastrol suppresses invasion of colon and pancreatic cancer cells through the downregulation of expression of CXCR4 chemokine receptor.
Author:	Yadav, Vivek R\|Sung, Bokyung\|Prasad, Sahdeo\|Kannappan, Ramaswamy\|Cho, Sung-Gook\|Liu, Mingyao\|Chaturvedi, Madan M\|Aggarwal, Bharat B
PMID:	20798912

57.
Journal:	BMC Cancer. 2010 Dec 3;10:668.
Title:	Activating transcription factor-3 (ATF3) functions as a tumor suppressor in colon cancer and is up-regulated upon heat-shock protein 90 (Hsp90) inhibition.
Author:	Hackl, Christina\|Lang, Sven A\|Moser, Christian\|Mori, Akira\|Fichtner-Feigl, Stefan\|Hellerbrand, Claus\|Dietmeier, Wolfgang\|Schlitt, Hans J\|Geissler, Edward K\|Stoeltzing, Oliver
PMID:	21129190

58.
Journal:	Bioorg Med Chem. 2011 Mar 1;19(5):1714-20.
Title:	Structure based design of heat shock protein 90 inhibitors acting as anticancer agents.
Author:	Doddareddy, Munikumar Reddy\|Thorat, Dhanaji Achyutrao\|Seo, Seon Hee\|Hong, Tae-Joon\|Cho, Yong Seo\|Hahn, Ji-Sook\|Pae, Ae Nim
PMID:	21306907

59.
Journal:	Chem Res Toxicol. 2011 Aug 15;24(8):1275-82.
Title:	Protein-selective capture to analyze electrophile adduction of hsp90 by 4-hydroxynonenal.
Author:	Connor, Rebecca E\|Marnett, Lawrence J\|Liebler, Daniel C
PMID:	21749116

60.
Journal:	J Antibiot (Tokyo). 2011 Sep;64(9):635-44.
Title:	Molecular basis for the actions of Hsp90 inhibitors and cancer therapy.
Author:	Yamaki, Hiroshi\|Nakajima, Motowo\|Shimotohno, Kumiko W\|Tanaka, Nobuo
PMID:	21811259

61.
Journal:	ACS Chem Biol. 2011 Dec 16;6(12):1339-47.
Title:	Targeting the Hsp90 molecular chaperone with novel macrolactams. Synthesis, structural, binding, and cellular studies.
Author:	Day, James E H\|Sharp, Swee Y\|Rowlands, Martin G\|Aherne, Wynne\|Hayes, Angela\|Raynaud, Florence I\|Lewis, William\|Roe, S Mark\|Prodromou, Chrisostomos\|Pearl, Laurence H\|Workman, Paul\|Moody, Christopher J
PMID:	21932796

62.
Journal:	DNA Cell Biol. 2012 Jan;31(1):15-29.
Title:	Cooperative enhancement of radiosensitivity after combined treatment of 17-(allylamino)-17-demethoxygeldanamycin and celecoxib in human lung and colon cancer cell lines.
Author:	Kim, Young-Mee\|Pyo, Hongryull
PMID:	21830942

63.
Journal:	Genes Nutr. 2012 Apr;7(2):235-46.
Title:	Impact of butyrate on PKM2 and HSP90beta expression in human colon tissues of different transformation stages: a comparison of gene and protein data.
Author:	Jahns, Franziska\|Wilhelm, Anne\|Greulich, Karl Otto\|Mothes, Henning\|Radeva, Mariya\|Wolfert, Anja\|Glei, Michael
PMID:	22009386

64.
Journal:	Biochem Pharmacol. 2012 Feb 1;83(3):355-67.
Title:	Hsp90 inhibitors sensitise human colon cancer cells to topoisomerase I poisons by depletion of key anti-apoptotic and cell cycle checkpoint proteins.
Author:	McNamara, Anne V\|Barclay, Monica\|Watson, Alastair J M\|Jenkins, John R
PMID:	22138446

65.
Journal:	J Cancer Res Clin Oncol. 2012 Mar;138(3):387-95.
Title:	Possible predictors of histopathological response to neoadjuvant chemoradiotherapy for rectal cancer.
Author:	Farkas, Robert\|Pozsgai, Eva\|Schally, Andrew V\|Szigeti, Andras\|Szigeti, Edit\|Laszlo, Zoltan\|Papp, Andras\|Gomori, Eva\|Mangel, Laszlo\|Horvath, Peter O\|Bellyei, Szabolcs
PMID:	22160161

66.
Journal:	Bioorg Med Chem Lett. 2012 Jan 15;22(2):1136-41.
Title:	Design and synthesis of novel macrocyclic 2-amino-6-arylpyrimidine Hsp90 inhibitors.
Author:	Suda, Atsushi\|Koyano, Hiroshi\|Hayase, Tadakatsu\|Hada, Kihito\|Kawasaki, Ken-Ichi\|Komiyama, Susumu\|Hasegawa, Kiyoshi\|Fukami, Takaaki A\|Sato, Shigeo\|Miura, Takaaki\|Ono, Naomi\|Yamazaki, Toshikazu\|Saitoh, Ryoichi\|Shimma, Nobuo\|Shiratori, Yasuhiko\|Tsukuda, Taku
PMID:	22192591

67.
Journal:	J Exp Med. 2012 Apr 9;209(4):697-711.
Title:	Targeting of KRAS mutant tumors by HSP90 inhibitors involves degradation of STK33.
Author:	Azoitei, Ninel\|Hoffmann, Christopher M\|Ellegast, Jana M\|Ball, Claudia R\|Obermayer, Kerstin\|Gossele, Ulrike\|Koch, Britta\|Faber, Katrin\|Genze, Felicitas\|Schrader, Mark\|Kestler, Hans A\|Dohner, Hartmut\|Chiosis, Gabriela\|Glimm, Hanno\|Frohling, Stefan\|Scholl, C
PMID:	22451720

68.
Journal:	Cell Mol Biol Lett. 2012 Sep;17(3):446-58.
Title:	Alterations of the Hsp70/Hsp90 chaperone and the HOP/CHIP co-chaperone system in cancer.
Author:	Ruckova, Eva\|Muller, Petr\|Nenutil, Rudolf\|Vojtesek, Borivoj
PMID:	22669480

69.
Journal:	Br J Anaesth. 2012 Nov;109(5):754-61.
Title:	Effect of preoperative fever-range whole-body hyperthermia on immunological markers in patients undergoing colorectal cancer surgery.
Author:	Sulyok, I\|Fleischmann, E\|Stift, A\|Roth, G\|Lebherz-Eichinger, D\|Kasper, D\|Spittler, A\|Kimberger, O
PMID:	22855633

70.
Journal:	PLoS One. 2012;7(9):e44642.
Title:	Co-crystalization and in vitro biological characterization of 5-aryl-4-(5-substituted-2-4-dihydroxyphenyl)-1,2,3-thiadiazole Hsp90 inhibitors.
Author:	Sharp, Swee Y\|Roe, S Mark\|Kazlauskas, Egidijus\|Cikotiene, Inga\|Workman, Paul\|Matulis, Daumantas\|Prodromou, Chrisostomos
PMID:	22984537

71.
Journal:	Br J Cancer. 2013 Feb 5;108(2):342-50.
Title:	A novel small molecule hydroxamate preferentially inhibits HDAC6 activity and tumour growth.
Author:	Kaliszczak, M\|Trousil, S\|Aberg, O\|Perumal, M\|Nguyen, Q-D\|Aboagye, E O
PMID:	23322205

72.
Journal:	Ann Surg Oncol. 2013 Apr;20(4):1105-13.
Title:	Hyperthermic intraperitoneal chemotherapy in patients with peritoneal carcinomatosis: role of heat shock proteins and dissecting effects of hyperthermia.
Author:	Pelz, Joerg O W\|Vetterlein, Malte\|Grimmig, Tanja\|Kerscher, Alexander G\|Moll, Eva\|Lazariotou, Maria\|Matthes, Niels\|Faber, Marc\|Germer, Christoph-Thomas\|Waaga-Gasser, Ana Maria\|Gasser, Martin
PMID:	23456378

73.
Journal:	J Amino Acids. 2013;2013:509056.
Title:	DTNQ-Pro, a Mimetic Dipeptide, Sensitizes Human Colon Cancer Cells to 5-Fluorouracil Treatment.
Author:	Gomez-Monterrey, Isabel\|Campiglia, Pietro\|Scognamiglio, Ilaria\|Vanacore, Daniela\|Dicitore, Alessandra\|Lombardi, Angela\|Caraglia, Michele\|Novellino, Ettore\|Stiuso, Paola
PMID:	23710334

74.
Journal:	Angiogenesis. 2013 Oct;16(4):903-17.
Title:	Antiangiogenic effects of ganetespib in colorectal cancer mediated through inhibition of HIF-1alpha and STAT-3.
Author:	Nagaraju, Ganji Purnachandra\|Park, Wungki\|Wen, Jing\|Mahaseth, Hemchandra\|Landry, Jerome\|Farris, Alton B\|Willingham, Field\|Sullivan, Patrick S\|Proia, David A\|El-Hariry, Iman\|Taliaferro-Smith, Latonia\|Diaz, Roberto\|El-Rayes, Bassel F
PMID:	23838996

75.
Journal:	Evid Based Complement Alternat Med. 2013;2013:987612.
Title:	HSP90 Inhibitors, Geldanamycin and Radicicol, Enhance Fisetin-Induced Cytotoxicity via Induction of Apoptosis in Human Colonic Cancer Cells.
Author:	Wu, Ming-Shun\|Lien, Gi-Shih\|Shen, Shing-Chuan\|Yang, Liang-Yo\|Chen, Yen-Chou
PMID:	23840275

76.
Journal:	Oncotarget. 2013 Aug;4(8):1185-98.
Title:	Combining trail with PI3 kinase or HSP90 inhibitors enhances apoptosis in colorectal cancer cells via suppression of survival signaling.
Author:	Saturno, Grazia\|Valenti, Melanie\|De Haven Brandon, Alexis\|Thomas, George V\|Eccles, Suzanne\|Clarke, Paul A\|Workman, Paul
PMID:	23852390

77.
Journal:	Oncotarget. 2013 Nov;4(11):1963-75.
Title:	Mode of cell death induced by the HSP90 inhibitor 17-AAG (tanespimycin) is dependent on the expression of pro-apoptotic BAX.
Author:	Powers, Marissa V\|Valenti, Melanie\|Miranda, Susana\|Maloney, Alison\|Eccles, Suzanne A\|Thomas, George\|Clarke, Paul A\|Workman, Paul
PMID:	24185264

78.
Journal:	Curr Colorectal Cancer Rep. 2013 Dec;9(4).
Title:	Role of apoptosis in colon cancer biology, therapy, and prevention.
Author:	Zhang, Lin\|Yu, Jian
PMID:	24273467

79.
Journal:	J Biol Chem. 2014 Mar 7;289(10):6513-25.
Title:	p53 protein regulates Hsp90 ATPase activity and thereby Wnt signaling by modulating Aha1 expression.
Author:	Okayama, Sachiyo\|Kopelovich, Levy\|Balmus, Gabriel\|Weiss, Robert S\|Herbert, Brittney-Shea\|Dannenberg, Andrew J\|Subbaramaiah, Kotha
PMID:	24451373

80.
Journal:	Invest New Drugs. 2014 Aug;32(4):577-86.
Title:	The HSP90 inhibitor ganetespib has chemosensitizer and radiosensitizer activity in colorectal cancer.
Author:	He, Suqin\|Smith, Donald L\|Sequeira, Manuel\|Sang, Jim\|Bates, Richard C\|Proia, David A
PMID:	24682747

81.
Journal:	Int J Colorectal Dis. 2014 Jun;29(6):663-71.
Title:	Expression analysis of heat shock protein 90 (HSP90) and Her2 in colon carcinoma.
Author:	Drecoll, Enken\|Nitsche, Ulrich\|Bauer, Karina\|Berezowska, Sabina\|Slotta-Huspenina, Julia\|Rosenberg, Robert\|Langer, Rupert
PMID:	24733427

82.
Journal:	Oncotarget. 2014 Jun 30;5(12):4269-82.
Title:	Identification of a ternary protein-complex as a therapeutic target for K-Ras-dependent colon cancer.
Author:	Qi, Xiaomei\|Xie, Congying\|Hou, Songwang\|Li, Gang\|Yin, Ning\|Dong, Lei\|Lepp, Adrienne\|Chesnik, Marla A\|Mirza, Shama P\|Szabo, Aniko\|Tsai, Susan\|Basir, Zainab\|Wu, Shixiu\|Chen, Guan
PMID:	24962213

83.
Journal:	Mol Oncol. 2014 Dec;8(8):1482-94.
Title:	TRAP1-dependent regulation of p70S6K is involved in the attenuation of protein synthesis and cell migration: relevance in human colorectal tumors.
Author:	Matassa, Danilo Swann\|Agliarulo, Ilenia\|Amoroso, Maria Rosaria\|Maddalena, Francesca\|Sepe, Leandra\|Ferrari, Maria Carla\|Sagar, Vinay\|D'Amico, Silvia\|Loreni, Fabrizio\|Paolella, Giovanni\|Landriscina, Matteo\|Esposito, Franca
PMID:	24962791

84.
Journal:	Cell Death Dis. 2014 Sep 11;5:e1411.
Title:	UDP glucuronosyltransferase 1A expression levels determine the response of colorectal cancer cells to the heat shock protein 90 inhibitor ganetespib.
Author:	Landmann, H\|Proia, D A\|He, S\|Ogawa, L S\|Kramer, F\|Beissbarth, T\|Grade, M\|Gaedcke, J\|Ghadimi, M\|Moll, U\|Dobbelstein, M
PMID:	25210794

85.
Journal:	Cancer Res. 2014 Nov 15;74(22):6693-704.
Title:	TRAP1 is involved in BRAF regulation and downstream attenuation of ERK phosphorylation and cell-cycle progression: a novel target for BRAF-mutated colorectal tumors.
Author:	Condelli, Valentina\|Piscazzi, Annamaria\|Sisinni, Lorenza\|Matassa, Danilo Swann\|Maddalena, Francesca\|Lettini, Giacomo\|Simeon, Vittorio\|Palladino, Giuseppe\|Amoroso, Maria Rosaria\|Trino, Stefania\|Esposito, Franca\|Landriscina, Matteo
PMID:	25239454

86.
Journal:	Oncotarget. 2014 Oct 30;5(20):9980-91.
Title:	HSP90 inhibition downregulates thymidylate synthase and sensitizes colorectal cancer cell lines to the effect of 5FU-based chemotherapy.
Author:	Nagaraju, Ganji Purnachandra\|Alese, Olatunji B\|Landry, Jerome\|Diaz, Roberto\|El-Rayes, Bassel F
PMID:	25296971

87.
Journal:	Transl Oncol. 2014 Oct 24;7(5):590-604.
Title:	Comparative Study of 17-AAG and NVP-AUY922 in Pancreatic and Colorectal Cancer Cells: Are There Common Determinants of Sensitivity?
Author:	Mayor-Lopez, Leticia\|Tristante, Elena\|Carballo-Santana, Mar\|Carrasco-Garcia, Estefania\|Grasso, Silvina\|Garcia-Morales, Pilar\|Saceda, Miguel\|Lujan, Juan\|Garcia-Solano, Jose\|Carballo, Fernando\|de Torre, Carlos\|Martinez-Lacaci, Isabel
PMID:	25389454

88.
Journal:	Clin Colorectal Cancer. 2014 Dec;13(4):207-12.
Title:	Ganetespib, a novel Hsp90 inhibitor in patients with KRAS mutated and wild type, refractory metastatic colorectal cancer.
Author:	Cercek, Andrea\|Shia, Jinru\|Gollub, Marc\|Chou, Joanne F\|Capanu, Marinela\|Raasch, Pamela\|Reidy-Lagunes, Diane\|Proia, David A\|Vakiani, Efsevia\|Solit, David B\|Saltz, Leonard B
PMID:	25444464

89.
Journal:	Oncogene. 2015 Jan 2;34(1):15-26.
Title:	Restricting direct interaction of CDC37 with HSP90 does not compromise chaperoning of client proteins.
Author:	Smith, J R\|de Billy, E\|Hobbs, S\|Powers, M\|Prodromou, C\|Pearl, L\|Clarke, P A\|Workman, P
PMID:	24292678

90.
Journal:	Cell Stress Chaperones. 2015 Jan;20(1):37-46.
Title:	Upregulation of heat shock proteins and the promotion of damage-associated molecular pattern signals in a colorectal cancer model by modulated electrohyperthermia.
Author:	Andocs, Gabor\|Meggyeshazi, Nora\|Balogh, Lajos\|Spisak, Sandor\|Maros, Mate Elod\|Balla, Peter\|Kiszner, Gergo\|Teleki, Ivett\|Kovago, Csaba\|Krenacs, Tibor
PMID:	24973890

91.
Journal:	Cell Signal. 2015 Feb;27(2):293-305.
Title:	HSP90 inhibitor NVP-AUY922 enhances TRAIL-induced apoptosis by suppressing the JAK2-STAT3-Mcl-1 signal transduction pathway in colorectal cancer cells.
Author:	Lee, Dae-Hee\|Sung, Ki Sa\|Bartlett, David L\|Kwon, Yong Tae\|Lee, Yong J
PMID:	25446253

92.
Journal:	Cancer Chemother Pharmacol. 2015 Feb;75(2):411-20.
Title:	Cks1 proteasomal degradation is induced by inhibiting Hsp90-mediated chaperoning in cancer cells.
Author:	Khattar, Vinayak\|Fried, Joshua\|Xu, Bo\|Thottassery, Jaideep V
PMID:	25544127

93.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2015 Apr;18(4):370-5.
Title:	[Co-inhibition effect of 17-DMAG and oxaliplatin on proliferation and invasion of colorectal cancer cells].
Author:	Zhou, Jianping\|Wang, Weimin\|Deng, Jianliang\|Zhou, Yan\|Wu, Lulu\|Guo, Zhiyuan\|Shi, Jianneng\|Shi, Jun\|Zhou, Sujun\|Xu, Zekuan
PMID:	25940182

94.
Journal:	Biochim Biophys Acta. 2015 Oct;1853(10 Pt A):2261-72.
Title:	Targeting of multiple oncogenic signaling pathways by Hsp90 inhibitor alone or in combination with berberine for treatment of colorectal cancer.
Author:	Su, Yen-Hao\|Tang, Wan-Chun\|Cheng, Ya-Wen\|Sia, Peik\|Huang, Chi-Chen\|Lee, Yi-Chao\|Jiang, Hsin-Yi\|Wu, Ming-Heng\|Lai, I-Lu\|Lee, Jun-Wei\|Lee, Kuen-Haur
PMID:	25982393

95.
Journal:	Oncotarget. 2015 Sep 8;6(26):22298-309.
Title:	Targeting TRAP1 as a downstream effector of BRAF cytoprotective pathway: a novel strategy for human BRAF-driven colorectal carcinoma.
Author:	Condelli, Valentina\|Maddalena, Francesca\|Sisinni, Lorenza\|Lettini, Giacomo\|Matassa, Danilo Swann\|Piscazzi, Annamaria\|Palladino, Giuseppe\|Amoroso, Maria Rosaria\|Esposito, Franca\|Landriscina, Matteo
PMID:	26084290

96.
Journal:	Oncotarget. 2015 Jul 30;6(21):18590-601.
Title:	Anticancer activity of MPT0G157, a derivative of indolylbenzenesulfonamide, inhibits tumor growth and angiogenesis.
Author:	Huang, Yen-Chia\|Huang, Fang-I\|Mehndiratta, Samir\|Lai, Ssu-Chia\|Liou, Jing-Ping\|Yang, Chia-Ron
PMID:	26087180

97.
Journal:	Data Brief. 2015 Jun 12;4:235-8.
Title:	Data supporting the identification of compound for inhibition of survivin of colorectal cancer by using ingenuity pathway analysis of gene expression profiling of colorectal cancer tissues.
Author:	Lee, Yi-Chao\|Lee, Jun-Wei\|Huang, Chi-Chen\|Wu, Ming-Heng\|Lee, Kuen-Haur
PMID:	26217796

98.
Journal:	Eur J Pharmacol. 2015 Oct 15;765:217-27.
Title:	Blockade of autophagy enhances proapoptotic potential of BI-69A11, a novel Akt inhibitor, in colon carcinoma.
Author:	Pal, Ipsita\|Parida, Sheetal\|Prashanth Kumar, B N\|Banik, Payel\|Kumar Dey, Kaushik\|Chakraborty, Sandipan\|Bhutia, Sujit K\|Mandal, Mahitosh
PMID:	26306675

99.
Journal:	Oncotarget. 2015 Sep 22;6(28):25202-16.
Title:	Adenomatous polyposis coli mutants dominantly activate Hsf1-dependent cell stress pathways through inhibition of microtubule dynamics.
Author:	Davies, Alexander E\|Kortright, Kaitlyn\|Kaplan, Kenneth B
PMID:	26320184

100.
Journal:	Oncotarget. 2015 Oct 20;6(32):32622-33.
Title:	Acquired resistance to 5-fluorouracil via HSP90/Src-mediated increase in thymidylate synthase expression in colon cancer.
Author:	Ahn, Ji-Young\|Lee, Ji-Sun\|Min, Hye-Young\|Lee, Ho-Young
PMID:	26416450

101.
Journal:	Asian Pac J Cancer Prev. 2015;16(18):8563-6.
Title:	Effect of Root Extracts of Medicinal Herb Glycyrrhiza glabra on HSP90 Gene Expression and Apoptosis in the HT-29 Colon Cancer Cell Line.
Author:	Nourazarian, Seyed Manuchehr\|Nourazarian, Alireza\|Majidinia, Maryam\|Roshaniasl, Elmira
PMID:	26745117

102.
Journal:	Oncogene. 2016 Jan 14;35(2):261-8.
Title:	Hyperthermic intraperitoneal chemotherapy leads to an anticancer immune response via exposure of cell surface heat shock protein 90.
Author:	Zunino, B\|Rubio-Patino, C\|Villa, E\|Meynet, O\|Proics, E\|Cornille, A\|Pommier, S\|Mondragon, L\|Chiche, J\|Bereder, J-M\|Carles, M\|Ricci, J-E
PMID:	25867070

103.
Journal:	Bioorg Med Chem Lett. 2016 Mar 1;26(5):1443-51.
Title:	Discovery of potent and selective CDK8 inhibitors from an HSP90 pharmacophore.
Author:	Schiemann, Kai\|Mallinger, Aurelie\|Wienke, Dirk\|Esdar, Christina\|Poeschke, Oliver\|Busch, Michael\|Rohdich, Felix\|Eccles, Suzanne A\|Schneider, Richard\|Raynaud, Florence I\|Czodrowski, Paul\|Musil, Djordje\|Schwarz, Daniel\|Urbahns, Klaus\|Blagg, Julian
PMID:	26852363

104.
Journal:	Anticancer Drugs. 2016 Jun;27(5):417-26.
Title:	Acquired resistance to HSP90 inhibitor 17-AAG and increased metastatic potential are associated with MUC1 expression in colon carcinoma cells.
Author:	Liu, Xin\|Ban, Li-Li\|Luo, Gang\|Li, Zhi-Yao\|Li, Yun-Feng\|Zhou, Yong-Chun\|Wang, Xi-Cai\|Jin, Cong-Guo\|Ye, Jia-Gui\|Ma, Ding-Ding\|Xie, Qing\|Huang, You-Guang
PMID:	26872308

105.
Journal:	PeerJ. 2016 Feb 11;4:e1683.
Title:	Heat shock protein 90 is involved in the regulation of HMGA2-driven growth and epithelial-to-mesenchymal transition of colorectal cancer cells.
Author:	Kao, Chun-Yu\|Yang, Pei-Ming\|Wu, Ming-Heng\|Huang, Chi-Chen\|Lee, Yi-Chao\|Lee, Kuen-Haur
PMID:	26893968

106.
Journal:	Adv Cancer Res. 2016;129:165-90.
Title:	GRP94/gp96 in Cancer: Biology, Structure, Immunology, and Drug Development.
Author:	Wu, Bill X\|Hong, Feng\|Zhang, Yongliang\|Ansa-Addo, Ephraim\|Li, Zihai
PMID:	26916005

107.
Journal:	Cancer Prev Res (Phila). 2016 Jun;9(6):491-501.
Title:	Paricalcitol Enhances the Chemopreventive Efficacy of 5-Fluorouracil on an Intermediate-Term Model of Azoxymethane-Induced Colorectal Tumors in Rats.
Author:	El-Shemi, Adel Galal\|Refaat, Bassem\|Kensara, Osama Adnan\|Mohamed, Amr Mohamed\|Idris, Shakir\|Ahmad, Jawwad
PMID:	27020656

108.
Journal:	Curr Top Med Chem. 2016;16(25):2765-78.
Title:	Clients and Oncogenic Roles of Molecular Chaperone gp96/grp94.
Author:	Ansa-Addo, Ephraim A\|Thaxton, Jessica\|Hong, Feng\|Wu, Bill X\|Zhang, Yongliang\|Fugle, Caroline W\|Metelli, Alessandra\|Riesenberg, Brian\|Williams, Katelyn\|Gewirth, Daniel T\|Chiosis, Gabriela\|Liu, Bei\|Li, Zihai
PMID:	27072698

109.
Journal:	Inflammation. 2016 Jun;39(3):1116-23.
Title:	HSP90 Inhibition Suppresses PGE2 Production via Modulating COX-2 and 15-PGDH Expression in HT-29 Colorectal Cancer Cells.
Author:	Mohammadi, A\|Yaghoobi, M M\|Gholamhoseinian Najar, A\|Kalantari-Khandani, B\|Sharifi, H\|Saravani, M
PMID:	27075590

110.
Journal:	Oncotarget. 2016 Jun 21;7(25):38191-38209.
Title:	Dual PI3K- and mTOR-inhibitor PI-103 can either enhance or reduce the radiosensitizing effect of the Hsp90 inhibitor NVP-AUY922 in tumor cells: The role of drug-irradiation schedule.
Author:	Djuzenova, Cholpon S\|Fiedler, Vanessa\|Katzer, Astrid\|Michel, Konstanze\|Deckert, Stefanie\|Zimmermann, Heiko\|Sukhorukov, Vladimir L\|Flentje, Michael
PMID:	27224913

111.
Journal:	Oncotarget. 2016 Jul 12;7(28):43199-43219.
Title:	A novel HSP90 inhibitor with reduced hepatotoxicity synergizes with radiotherapy to induce apoptosis, abrogate clonogenic survival, and improve tumor control in models of colorectal cancer.
Author:	Kinzel, Linda\|Ernst, Anne\|Orth, Michael\|Albrecht, Valerie\|Hennel, Roman\|Brix, Nikko\|Frey, Benjamin\|Gaipl, Udo S\|Zuchtriegel, Gabriele\|Reichel, Christoph A\|Blutke, Andreas\|Schilling, Daniela\|Multhoff, Gabriele\|Li, Minglun\|Niyazi, Maximilian\|Friedl, Anna A\|
PMID:	27259245

112.
Journal:	Oncotarget. 2016 Aug 2;7(31):49597-49610.
Title:	Reactivation of ERK and Akt confers resistance of mutant BRAF colon cancer cells to the HSP90 inhibitor AUY922.
Author:	Wang, Chun Yan\|Guo, Su Tang\|Wang, Jia Yu\|Yan, Xu Guang\|Farrelly, Margaret\|Zhang, Yuan Yuan\|Liu, Fen\|Yari, Hamed\|La, Ting\|Lei, Fu Xi\|Jin, Lei\|Zhang, Xu Dong\|Jiang, Chen Chen
PMID:	27391062

113.
Journal:	Oncotarget. 2016 Aug 23;7(34):55663-55676.
Title:	CD24 promoted cancer cell angiogenesis via Hsp90-mediated STAT3/VEGF signaling pathway in colorectal cancer.
Author:	Wang, Xinying\|Zhang, Yu\|Zhao, Yingying\|Liang, Yanling\|Xiang, Cheng\|Zhou, Huanyu\|Zhang, Hui\|Zhang, Qiang\|Qing, Haitao\|Jiang, Bo\|Xiong, Huabao\|Peng, Liang
PMID:	27494878

114.
Journal:	PLoS One. 2016 Nov 1;11(11):e0165227.
Title:	Identification of Tumor Antigen AF20 as Glycosylated Transferrin Receptor 1 in Complex with Heat Shock Protein 90 and/or Transporting ATPase.
Author:	Shapiro, Jason M\|Chung, Waihong\|Ogawa, Kosuke\|Barker, Luke\|Carlson, Rolf\|Wands, Jack R\|Li, Jisu
PMID:	27802297

115.
Journal:	Pathologe. 2016 Nov;37(Suppl 2):191-195.
Title:	[Pancreatic acinar neoplasms : Comparative molecular characterization].
Author:	Bergmann, F
PMID:	27807633

116.
Journal:	Cell Mol Biol (Noisy-le-grand). 2016 Oct 31;62(12):62-67.
Title:	HSP90 inhibitor enhances anti-proliferative and apoptotic effects of celecoxib on HT-29 colorectal cancer cells via increasing BAX/BCL-2 ratio.
Author:	Mohammadi, A\|Yaghoobi, M M\|GholamhoseynianNajar, A\|Kalantari-Khandani, B\|Sharifi, H\|Saravani, M
PMID:	27894402

117.
Journal:	Cell Stress Chaperones. 2017 Mar;22(2):293-306.
Title:	Re-examining HSPC1 inhibitors.
Author:	Lee, Sheah Lin\|Dempsey-Hibbert, Nina Claire\|Vimalachandran, Dale\|Wardle, Terence David\|Sutton, Paul A\|Williams, John H H
PMID:	28255900

118.
Journal:	BMC Cancer. 2017 Mar 16;17(1):202.
Title:	Extracellular Hsp90 and TGFbeta regulate adhesion, migration and anchorage independent growth in a paired colon cancer cell line model.
Author:	de la Mare, Jo-Anne\|Jurgens, Tamarin\|Edkins, Adrienne L
PMID:	28302086

119.
Journal:	Cancer Lett. 2017 Aug 28;402:110-116.
Title:	Epigenetic effects of inhibition of heat shock protein 90 (HSP90) in human pancreatic and colon cancer.
Author:	Nagaraju, Ganji Purnachandra\|Wu, Christina\|Merchant, Neha\|Chen, Zhengjia\|Lesinski, Gregory B\|El-Rayes, Bassel F
PMID:	28583846

120.
Journal:	Mol Cancer Ther. 2017 Sep;16(9):1979-1988.
Title:	FBW7-Dependent Mcl-1 Degradation Mediates the Anticancer Effect of Hsp90 Inhibitors.
Author:	Tong, Jingshan\|Tan, Shuai\|Nikolovska-Coleska, Zaneta\|Yu, Jian\|Zou, Fangdong\|Zhang, Lin
PMID:	28619760

121.
Journal:	Oncol Lett. 2017 Aug;14(2):2177-2185.
Title:	Effects of 17-allylamino-17-demethoxygeldanamycin on the induction of apoptosis and cell cycle arrest in HCT-116 cells.
Author:	Zhao, Xuerong\|Wang, Jianping\|Xiao, Lijun\|Xu, Qian\|Zhao, Enhong\|Zheng, Xin\|Zheng, Huachuan\|Zhao, Shuang\|Ding, Shi
PMID:	28789442

122.
Journal:	Oncotarget. 2017 Aug 24;8(44):77474-77488.
Title:	STK33 participates to HSP90-supported angiogenic program in hypoxic tumors by regulating HIF-1alpha/VEGF signaling pathway.
Author:	Liu, Yang\|Steinestel, Konrad\|Rouhi, Arefeh\|Armacki, Milena\|Diepold, Kristina\|Chiosis, Gabriela\|Simmet, Thomas\|Seufferlein, Thomas\|Azoitei, Ninel
PMID:	29100402

123.
Journal:	Am J Transl Res. 2017 Nov 15;9(11):4945-4953. eCollection 2017.
Title:	Hsp90 inhibitor sensitizes TRAIL-mediated apoptosis via chop-dependent DR5 upregulation in colon cancer cells.
Author:	Yao, Zhicheng\|Chen, Ang\|Li, Xin\|Zhu, Zhiyong\|Jiang, Xin
PMID:	29218092

124.
Journal:	Gastroenterol Hepatol Bed Bench. 2017 Fall;10(4):295-302.
Title:	Network analysis of common genes related to esophageal, gastric, and colon cancers.
Author:	Vaseghi Maghvan, Padina\|Rezaei-Tavirani, Mostafa\|Zali, Hakimeh\|Nikzamir, Abdolrahim\|Abdi, Saeed\|Khodadoostan, Mahsa\|Asadzadeh-Aghdaei, Hamid
PMID:	29379595

125.
Journal:	Cancer Growth Metastasis. 2017 Sep 18;10:1179064417730559.
Title:	Upregulated Heat Shock Proteins After Hyperthermic Chemotherapy Point to Induced Cell Survival Mechanisms in Affected Tumor Cells From Peritoneal Carcinomatosis.
Author:	Grimmig, Tanja\|Moll, Eva-Maria\|Kloos, Kerstin\|Thumm, Rebecca\|Moench, Romana\|Callies, Simone\|Kreckel, Jennifer\|Vetterlein, Malte\|Pelz, Joerg\|Polat, Buelent\|Tripathi, Sudipta\|Rehder, Roberta\|Ribas, Carmen M\|Chandraker, Anil\|Germer, Christoph-T\|Waaga-Gasser,
PMID:	29403306

126.
Journal:	Clin Cancer Res. 2018 Feb 15;24(4):794-806.
Title:	Colorectal Cancer Consensus Molecular Subtypes Translated to Preclinical Models Uncover Potentially Targetable Cancer Cell Dependencies.
Author:	Sveen, Anita\|Bruun, Jarle\|Eide, Peter W\|Eilertsen, Ina A\|Ramirez, Lorena\|Murumagi, Astrid\|Arjama, Mariliina\|Danielsen, Stine A\|Kryeziu, Kushtrim\|Elez, Elena\|Tabernero, Josep\|Guinney, Justin\|Palmer, Hector G\|Nesbakken, Arild\|Kallioniemi, Olli\|Dienstmann, R
PMID:	29242316

127.
Journal:	Cancer Sci. 2018 Mar;109(3):656-665.
Title:	Cdc37 facilitates cell survival of colorectal carcinoma via activating the CDK4 signaling pathway.
Author:	Zhu, Jianjun\|Yan, Fang\|Tao, Jia\|Zhu, Xiaohua\|Liu, Jiayou\|Deng, Shishan\|Zhang, Xiaoming
PMID:	29288563

128.
Journal:	Onco Targets Ther. 2018 Jan 31;11:609-618.
Title:	Identification of genomic expression differences between right-sided and left-sided colon cancer based on bioinformatics analysis.
Author:	Peng, Qiliang\|Lin, Kaisu\|Chang, Tao\|Zou, Li\|Xing, Pengfei\|Shen, Yuntian\|Zhu, Yaqun
PMID:	29430186

129.
Journal:	Tumour Biol. 2018 Apr;40(4):1010428318770957.
Title:	Cyclin-dependent kinase 1 targeting improves sensitivity to radiation in BRAF V600E colorectal carcinoma cells.
Author:	Spagnoletti, Girolamo\|Li Bergolis, Valeria\|Piscazzi, Annamaria\|Giannelli, Francesca\|Condelli, Valentina\|Sisinni, Lorenza\|Bove, Giuseppe\|Storto, Giovanni\|Landriscina, Matteo
PMID:	29663854

130.
Journal:	Bioorg Med Chem Lett. 2018 Jul 15;28(13):2289-2293.
Title:	New TRAP1 and Hsp90 chaperone inhibitors with cationic components: Preliminary studies on mitochondrial targeting.
Author:	Rondanin, R\|Lettini, G\|Oliva, P\|Baruchello, R\|Costantini, C\|Trapella, C\|Simoni, D\|Bernardi, T\|Sisinni, L\|Pietrafesa, M\|Ponterini, G\|Costi, M P\|Vignudelli, T\|Luciani, R\|Matassa, D S\|Esposito, F\|Landriscina, M
PMID:	29807796

131.
Journal:	Hum Pathol. 2018 Sep;79:135-143.
Title:	Aberrant expression of stress-induced phosphoprotein 1 in colorectal cancer and its clinicopathologic significance.
Author:	Zhang, Zhimei\|Ren, Hui\|Yang, Liang\|Zhang, Xinhua\|Liang, Wei\|Wu, Hui\|Huang, Leilei\|Kang, Jihui\|Xu, Jianbo\|Zhai, Ertao\|Cai, Shirong\|He, Yulong
PMID:	29879402

132.
Journal:	Biomark Med. 2018 Aug;12(8):881-890.
Title:	Serum heat shock protein 90alpha have an advantage in diagnosis of colorectal cancer at early stage.
Author:	Kasanga, Maisa\|Liu, Lisheng\|Xue, Linlin\|Song, Xianrang
PMID:	29939072