Primary Site >> Colorectal Cancer
Gene >> HMGCR
| 1. | |||||||||||
| Journal: | Prog Food Nutr Sci. 1993 Jan-Mar;17(1):1-40. | ||||||||||
| Title: | Cholesterol metabolism and colon cancer. | ||||||||||
| Author: | Broitman, S A|Cerda, S|Wilkinson, J 4th | ||||||||||
| PMID: | 8502754 | ||||||||||
| 2. | |||||||||||
| Journal: | J Biol Chem. 1996 Jul 19;271(29):17453-62. | ||||||||||
| Title: | Mevalonic acid is limiting for N-linked glycosylation and translocation of the insulin-like growth factor-1 receptor to the cell surface. Evidence for a new link between 3-hydroxy-3-methylglutaryl-coenzyme a reductase and cell growth. | ||||||||||
| Author: | Carlberg, M|Dricu, A|Blegen, H|Wang, M|Hjertman, M|Zickert, P|Hoog, A|Larsson, O | ||||||||||
| PMID: | 8663239 | ||||||||||
| 3. | |||||||||||
| Journal: | Biochem Pharmacol. 1996 Jul 12;52(1):127-31. | ||||||||||
| Title: | Expression of the low-density lipoprotein receptor, HMG-CoA reductase, and multidrug resistance (Mdr1) genes in colorectal carcinomas. | ||||||||||
| Author: | Vitols, S|Gunven, P|Gruber, A|Larsson, O | ||||||||||
| PMID: | 8678896 | ||||||||||
| 4. | |||||||||||
| Journal: | Adv Exp Med Biol. 1996;401:111-30. | ||||||||||
| Title: | Effects of monoterpenes and mevinolin on murine colon tumor CT-26 in vitro and its hepatic "metastases" in vivo. | ||||||||||
| Author: | Broitman, S A|Wilkinson, J 4th|Cerda, S|Branch, S K | ||||||||||
| PMID: | 8886130 | ||||||||||
| 5. | |||||||||||
| Journal: | Scand J Gastroenterol. 2005 Dec;40(12):1454-61. | ||||||||||
| Title: | Estrogenic regulation of cholesterol biosynthesis and cell growth in DLD-1 human colon cancer cells. | ||||||||||
| Author: | Messa, Caterina|Notarnicola, Maria|Russo, Francesco|Cavallini, Aldo|Pallottini, Valentina|Trentalance, Anna|Bifulco, Maurizio|Laezza, Chiara|Gabriella Caruso, Maria | ||||||||||
| PMID: | 16293557 | ||||||||||
| 6. | |||||||||||
| Journal: | Cancer Lett. 2007 Oct 8;255(2):194-204. | ||||||||||
| Title: | Diosgenin, a naturally occurring steroid [corrected] saponin suppresses 3-hydroxy-3-methylglutaryl CoA reductase expression and induces apoptosis in HCT-116 human colon carcinoma cells. | ||||||||||
| Author: | Raju, Jayadev|Bird, Ranjana P | ||||||||||
| PMID: | 17555873 | ||||||||||
| 7. | |||||||||||
| Journal: | J Nutr Biochem. 2008 Jul;19(7):448-58. Epub 2007 Sep 14. | ||||||||||
| Title: | Anticancer effects of Chinese red yeast rice versus monacolin K alone on colon cancer cells. | ||||||||||
| Author: | Hong, Mee Young|Seeram, Navindra P|Zhang, Yanjun|Heber, David | ||||||||||
| PMID: | 17869085 | ||||||||||
| 8. | |||||||||||
| Journal: | Fitoterapia. 2008 Dec;79(7-8):524-8. | ||||||||||
| Title: | Early induction of LDL receptor gene expression by genistein in DLD-1 colon cancer cell line. | ||||||||||
| Author: | Caruso, Maria Gabriella|Messa, Caterina|Orlando, Antonella|D'Attoma, Benedetta|Notarnicola, Maria | ||||||||||
| PMID: | 18621112 | ||||||||||
| 9. | |||||||||||
| Journal: | Genes Nutr. 2008 Apr;3(1):35-40. | ||||||||||
| Title: | Effect of genistein on cholesterol metabolism-related genes in a colon cancer cell line. | ||||||||||
| Author: | Notarnicola, Maria|Messa, Caterina|Orlando, Antonella|D'Attoma, Benedetta|Tutino, Valeria|Rivizzigno, Rosemary|Caruso, Maria Gabriella | ||||||||||
| PMID: | 18850198 | ||||||||||
| 10. | |||||||||||
| Journal: | Cancer Prev Res (Phila). 2010 May;3(5):597-603. | ||||||||||
| Title: | Genetic variation in 3-hydroxy-3-methylglutaryl CoA reductase modifies the chemopreventive activity of statins for colorectal cancer. | ||||||||||
| Author: | Lipkin, Steven M|Chao, Elizabeth C|Moreno, Victor|Rozek, Laura S|Rennert, Hedy|Pinchev, Mila|Dizon, Diana|Rennert, Gad|Kopelovich, Levy|Gruber, Stephen B | ||||||||||
| PMID: | 20403997 | ||||||||||
| 11. | |||||||||||
| Journal: | Discov Med. 2010 Jun;9(49):495-9. | ||||||||||
| Title: | The relationship between HMGCR genetic variation, alternative splicing, and statin efficacy. | ||||||||||
| Author: | Medina, Marisa Wong | ||||||||||
| PMID: | 20587337 | ||||||||||
| 12. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2014 Mar 28;446(1):68-72. | ||||||||||
| Title: | HMG-CoA reductase regulates CCL17-induced colon cancer cell migration via geranylgeranylation and RhoA activation. | ||||||||||
| Author: | Al-Haidari, Amr A|Syk, Ingvar|Thorlacius, Henrik | ||||||||||
| PMID: | 24582560 | ||||||||||
| 13. | |||||||||||
| Journal: | Diagn Pathol. 2014 Apr 7;9:78. | ||||||||||
| Title: | HMG-CoA reductase expression in primary colorectal cancer correlates with favourable clinicopathological characteristics and an improved clinical outcome. | ||||||||||
| Author: | Bengtsson, Erik|Nerjovaj, Pashtrik|Wangefjord, Sakarias|Nodin, Bjorn|Eberhard, Jakob|Uhlen, Mathias|Borgquist, Signe|Jirstrom, Karin | ||||||||||
| PMID: | 24708688 | ||||||||||
| 14. | |||||||||||
| Journal: | Oncotarget. 2015 Jun 20;6(17):15332-47. | ||||||||||
| Title: | Inhibition of insulin-like growth factor receptor/AKT/mammalian target of rapamycin axis targets colorectal cancer stem cells by attenuating mevalonate-isoprenoid pathway in vitro and in vivo. | ||||||||||
| Author: | Sharon, Chetna|Baranwal, Somesh|Patel, Nirmita J|Rodriguez-Agudo, Daniel|Pandak, William M|Majumdar, Adhip P N|Krystal, Geoffrey|Patel, Bhaumik B | ||||||||||
| PMID: | 25895029 | ||||||||||
| 15. | |||||||||||
| Journal: | Int J Cancer. 2017 Jun 15;140(12):2701-2708. | ||||||||||
| Title: | Mendelian randomisation implicates hyperlipidaemia as a risk factor for colorectal cancer. | ||||||||||
| Author: | Rodriguez-Broadbent, Henry|Law, Philip J|Sud, Amit|Palin, Kimmo|Tuupanen, Sari|Gylfe, Alexandra|Hanninen, Ulrika A|Cajuso, Tatiana|Tanskanen, Tomas|Kondelin, Johanna|Kaasinen, Eevi|Sarin, Antti-Pekka|Ripatti, Samuli|Eriksson, Johan G|Rissanen, Harri|Knekt | ||||||||||
| PMID: | 28340513 | ||||||||||
| 16. | |||||||||||
| Journal: | Br J Cancer. 2017 Jun 6;116(12):1652-1659. | ||||||||||
| Title: | Statin use, candidate mevalonate pathway biomarkers, and colon cancer survival in a population-based cohort study. | ||||||||||
| Author: | Gray, Ronan T|Loughrey, Maurice B|Bankhead, Peter|Cardwell, Chris R|McQuaid, Stephen|O'Neill, Roisin F|Arthur, Kenneth|Bingham, Victoria|McGready, Claire|Gavin, Anna T|James, Jacqueline A|Hamilton, Peter W|Salto-Tellez, Manuel|Murray, Liam J|Coleman, Hele | ||||||||||
| PMID: | 28524155 | ||||||||||