Primary Site >> Colorectal Cancer

Gene >> HMGA1

Journal: J Gastroenterol. 2003;38(12):1144-9.
Title: High mobility group A1 is expressed in metastatic adenocarcinoma to the liver and intrahepatic cholangiocarcinoma, but not in hepatocellular carcinoma: its potential use in the diagnosis of liver neoplasms.
Author: Abe, Nobutsugu|Watanabe, Takashi|Izumisato, Yumi|Suzuki, Yutaka|Masaki, Tadahiko|Mori, Toshiyuki|Sugiyama, Masanori|Fusco, Alfredo|Atomi, Yutaka
PMID: 14714251
Journal: Cancer Res. 2007 Jan 1;67(1):41-56.
Title: Gene expression profiling reveals a massive, aneuploidy-dependent transcriptional deregulation and distinct differences between lymph node-negative and lymph node-positive colon carcinomas.
Author: Grade, Marian|Hormann, Patrick|Becker, Sandra|Hummon, Amanda B|Wangsa, Danny|Varma, Sudhir|Simon, Richard|Liersch, Torsten|Becker, Heinz|Difilippantonio, Michael J|Ghadimi, B Michael|Ried, Thomas
PMID: 17210682
Journal: Cancer Res. 2007 May 15;67(10):4620-9.
Title: Transcriptional control of the human high mobility group A1 gene: basal and oncogenic Ras-regulated expression.
Author: Cleynen, Isabelle|Huysmans, Christel|Sasazuki, Takehiko|Shirasawa, Senji|Van de Ven, Wim|Peeters, Kristel
PMID: 17510387
Journal: Int J Cancer. 2011 Mar 1;128(5):1069-79.
Title: A genomic strategy for the functional validation of colorectal cancer genes identifies potential therapeutic targets.
Author: Grade, Marian|Hummon, Amanda B|Camps, Jordi|Emons, Georg|Spitzner, Melanie|Gaedcke, Jochen|Hoermann, Patrick|Ebner, Reinhard|Becker, Heinz|Difilippantonio, Michael J|Ghadimi, B Michael|Beissbarth, Tim|Caplen, Natasha J|Ried, Thomas
PMID: 20473941
Journal: PLoS One. 2012;7(1):e30034.
Title: HMGA1 induces intestinal polyposis in transgenic mice and drives tumor progression and stem cell properties in colon cancer cells.
Author: Belton, Amy|Gabrovsky, Alexander|Bae, Young Kyung|Reeves, Ray|Iacobuzio-Donahue, Christine|Huso, David L|Resar, Linda M S
PMID: 22276142
Journal: Cancer Res. 2012 Aug 15;72(16):4097-109.
Title: Caveolin-1 increases aerobic glycolysis in colorectal cancers by stimulating HMGA1-mediated GLUT3 transcription.
Author: Ha, Tae-Kyu|Her, Nam-Gu|Lee, Min-Goo|Ryu, Byung-Kyu|Lee, Jin-Hee|Han, Jikhyon|Jeong, Seong-In|Kang, Min-Ju|Kim, Nam-Hoon|Kim, Hyo-Jong|Chi, Sung-Gil
PMID: 22706202
Journal: Cell Death Dis. 2012 Aug 30;3:e383.
Title: High-mobility group A1 protein inhibits p53-mediated intrinsic apoptosis by interacting with Bcl-2 at mitochondria.
Author: Esposito, F|Tornincasa, M|Federico, A|Chiappetta, G|Pierantoni, G M|Fusco, A
PMID: 22932725
Journal: Cell Biochem Funct. 2013 Apr;31(3):228-36.
Title: The Wnt/beta-catenin/T-cell factor 4 pathway up-regulates high-mobility group A1 expression in colon cancer.
Author: Bush, Bethany M|Brock, Ashton T|Deng, Jiayue A|Nelson, Ronald A|Sumter, Takita Felder
PMID: 22961697
Journal: Gastroenterology. 2013 Mar;144(3):624-635.e4.
Title: MicroRNA-137, an HMGA1 target, suppresses colorectal cancer cell invasion and metastasis in mice by directly targeting FMNL2.
Author: Liang, Li|Li, Xianzheng|Zhang, Xiaojing|Lv, Zhenbing|He, Guoyang|Zhao, Wei|Ren, Xiaoli|Li, Yuling|Bian, Xiuwu|Liao, Wenting|Liu, Wei|Yang, Guangying|Ding, Yanqing
PMID: 23201162
Journal: Oncol Rep. 2013 Sep;30(3):1488-96.
Title: Microarray analysis reveals that high mobility group A1 is involved in colorectal cancer metastasis.
Author: Takahashi, Yusuke|Sawada, Genta|Sato, Tetsuya|Kurashige, Junji|Mima, Kosuke|Matsumura, Tae|Uchi, Ryutaro|Ueo, Hiroki|Ishibashi, Masahisa|Takano, Yuki|Akiyoshi, Sayuri|Eguchi, Hidetoshi|Sudo, Tomoya|Sugimachi, Keishi|Tanaka, Jun-Ichi|Kudo, Shin-Ei|Doki, Yu
PMID: 23835740
Journal: Oncotarget. 2014 May 30;5(10):3234-45.
Title: HMGA1 silencing restores normal stem cell characteristics in colon cancer stem cells by increasing p53 levels.
Author: Puca, Francesca|Colamaio, Marianna|Federico, Antonella|Gemei, Marica|Tosti, Nadia|Bastos, Andre Uchimura|Del Vecchio, Luigi|Pece, Salvatore|Battista, Sabrina|Fusco, Alfredo
PMID: 24833610
Journal: BMC Cancer. 2014 Nov 20;14:851.
Title: High mobility group A1 protein expression reduces the sensitivity of colon and thyroid cancer cells to antineoplastic drugs.
Author: D'Angelo, Daniela|Mussnich, Paula|Rosa, Roberta|Bianco, Roberto|Tortora, Giampaolo|Fusco, Alfredo
PMID: 25409711
Journal: Pathol Oncol Res. 2014 Oct;20(4):847-51.
Title: HMGA1 interacts with beta-catenin to positively regulate Wnt/beta-catenin signaling in colorectal cancer cells.
Author: Xing, Junjie|Cao, Guangwen|Fu, Chuangang
PMID: 24696416
Journal: J Proteome Res. 2015 Mar 6;14(3):1420-31.
Title: HMGA1 drives metabolic reprogramming of intestinal epithelium during hyperproliferation, polyposis, and colorectal carcinogenesis.
Author: Williams, Michael D|Zhang, Xing|Belton, Amy S|Xian, Lingling|Huso, Tait|Park, Jeong-Jin|Siems, William F|Gang, David R|Resar, Linda M S|Reeves, Raymond|Hill, Herbert H Jr
PMID: 25643065
Journal: Oncotarget. 2015 Jul 10;6(19):17342-53.
Title: Deregulation of HMGA1 expression induces chromosome instability through regulation of spindle assembly checkpoint genes.
Author: Pierantoni, Giovanna Maria|Conte, Andrea|Rinaldo, Cinzia|Tornincasa, Mara|Gerlini, Raffaele|Federico, Antonella|Valente, Davide|Medico, Enzo|Fusco, Alfredo
PMID: 26009897
Journal: Cell Cycle. 2016;15(6):812-8.
Title: Hmga1 null mouse embryonic fibroblasts display downregulation of spindle assembly checkpoint gene expression associated to nuclear and karyotypic abnormalities.
Author: Pierantoni, Giovanna Maria|Conte, Andrea|Rinaldo, Cinzia|Tornincasa, Mara|Gerlini, Raffaele|Valente, Davide|Izzo, Antonella|Fusco, Alfredo
PMID: 26889953
Journal: Expert Opin Ther Targets. 2016 Oct;20(10):1169-79.
Title: HMGA1 silencing reduces stemness and temozolomide resistance in glioblastoma stem cells.
Author: Colamaio, Marianna|Tosti, Nadia|Puca, Francesca|Mari, Alessia|Gattordo, Rosaria|Kuzay, Yalcin|Federico, Antonella|Pepe, Anna|Sarnataro, Daniela|Ragozzino, Elvira|Raia, Maddalena|Hirata, Hidenari|Gemei, Marica|Mimori, Koshi|Del Vecchio, Luigi|Battista, Sab
PMID: 27486901
Journal: Br J Cancer. 2016 Sep 6;115(6):741-51.
Title: MicroRNA-214 suppresses growth, migration and invasion through a novel target, high mobility group AT-hook 1, in human cervical and colorectal cancer cells.
Author: Chandrasekaran, Karthik Subramanian|Sathyanarayanan, Anusha|Karunagaran, Devarajan
PMID: 27537384
Journal: J Proteome Res. 2016 Dec 2;15(12):4176-4187.
Title: Fecal Metabolome in Hmga1 Transgenic Mice with Polyposis: Evidence for Potential Screen for Early Detection of Precursor Lesions in Colorectal Cancer.
Author: Williams, Michael D|Xian, Lingling|Huso, Tait|Park, Jeong-Jin|Huso, David|Cope, Leslie M|Gang, David R|Siems, William F|Resar, Linda|Reeves, Raymond|Hill, Herbert H Jr
PMID: 27696867
Journal: Int J Oncol. 2017 May;50(5):1801-1809.
Title: H19 promotes the migration and invasion of colon cancer by sponging miR-138 to upregulate the expression of HMGA1.
Author: Yang, Qingqiang|Wang, Xin|Tang, Chunyan|Chen, Xuan|He, Jianjun
PMID: 28358427
Journal: Cancer Res. 2018 Apr 15;78(8):1890-1897.
Title: Lessons from the Crypt: HMGA1-Amping up Wnt for Stem Cells and Tumor Progression.
Author: Resar, Linda|Chia, Lionel|Xian, Lingling
PMID: 29618461
Journal: Epigenetics. 2018;13(4):386-397.
Title: Robust prediction of gene regulation in colorectal cancer tissues from DNA methylation profiles.
Author: Klett, Hagen|Balavarca, Yesilda|Toth, Reka|Gigic, Biljana|Habermann, Nina|Scherer, Dominique|Schrotz-King, Petra|Ulrich, Alexis|Schirmacher, Peter|Herpel, Esther|Brenner, Hermann|Ulrich, Cornelia M|Michels, Karin B|Busch, Hauke|Boerries, Melanie
PMID: 29697014