Primary Site >> Colorectal Cancer
Gene >> HK2
| 1. | |||||||||||
| Journal: | BMC Cancer. 2012 Jun 12;12:232. | ||||||||||
| Title: | MicroRNA-143 down-regulates Hexokinase 2 in colon cancer cells. | ||||||||||
| Author: | Gregersen, Lea H|Jacobsen, Anders|Frankel, Lisa B|Wen, Jiayu|Krogh, Anders|Lund, Anders H | ||||||||||
| PMID: | 22691140 | ||||||||||
| 2. | |||||||||||
| Journal: | J Gastrointest Surg. 2012 Feb;16(2):394-400. | ||||||||||
| Title: | Molecular mechanism underlying the detection of colorectal cancer by 18F-2-fluoro-2-deoxy-D-glucose positron emission tomography. | ||||||||||
| Author: | Izuishi, Kunihiko|Yamamoto, Yuka|Sano, Takanori|Takebayashi, Ryusuke|Nishiyama, Yoshihiro|Mori, Hirohito|Masaki, Tsutomu|Morishita, Asahiro|Suzuki, Yasuyuki | ||||||||||
| PMID: | 22065316 | ||||||||||
| 3. | |||||||||||
| Journal: | Mol Carcinog. 2014 Feb;53 Suppl 1:E107-18. | ||||||||||
| Title: | Wogonin reverses hypoxia resistance of human colon cancer HCT116 cells via downregulation of HIF-1alpha and glycolysis, by inhibiting PI3K/Akt signaling pathway. | ||||||||||
| Author: | Wang, Hu|Zhao, Li|Zhu, Li-Tao|Wang, Yu|Pan, Di|Yao, Jing|You, Qi-Dong|Guo, Qing-Long | ||||||||||
| PMID: | 23761018 | ||||||||||
| 4. | |||||||||||
| Journal: | Cancer Sci. 2014 Sep;105(9):1100-8. | ||||||||||
| Title: | Combined evaluation of hexokinase 2 and phosphorylated pyruvate dehydrogenase-E1alpha in invasive front lesions of colorectal tumors predicts cancer metabolism and patient prognosis. | ||||||||||
| Author: | Hamabe, Atsushi|Yamamoto, Hirofumi|Konno, Masamitsu|Uemura, Mamoru|Nishimura, Junichi|Hata, Taishi|Takemasa, Ichiro|Mizushima, Tsunekazu|Nishida, Naohiro|Kawamoto, Koichi|Koseki, Jun|Doki, Yuichiro|Mori, Masaki|Ishii, Hideshi | ||||||||||
| PMID: | 25060325 | ||||||||||
| 5. | |||||||||||
| Journal: | J Nucl Med. 2014 Dec;55(12):2038-44. | ||||||||||
| Title: | Regulation of 18F-FDG accumulation in colorectal cancer cells with mutated KRAS. | ||||||||||
| Author: | Iwamoto, Masayoshi|Kawada, Kenji|Nakamoto, Yuji|Itatani, Yoshiro|Inamoto, Susumu|Toda, Kosuke|Kimura, Hiroyuki|Sasazuki, Takehiko|Shirasawa, Senji|Okuyama, Hiroaki|Inoue, Masahiro|Hasegawa, Suguru|Togashi, Kaori|Sakai, Yoshiharu | ||||||||||
| PMID: | 25453050 | ||||||||||
| 6. | |||||||||||
| Journal: | Anticancer Drugs. 2015 Jan;26(1):15-24. | ||||||||||
| Title: | Curcumin inhibits aerobic glycolysis and induces mitochondrial-mediated apoptosis through hexokinase II in human colorectal cancer cells in vitro. | ||||||||||
| Author: | Wang, Ke|Fan, Hua|Chen, Qingsen|Ma, Guojian|Zhu, Ming|Zhang, Xiaomei|Zhang, Yuanying|Yu, Jun | ||||||||||
| PMID: | 25229889 | ||||||||||
| 7. | |||||||||||
| Journal: | Mol Med Rep. 2015 Jul;12(1):426-34. | ||||||||||
| Title: | Metastasis-associated in colon cancer-1 is associated with poor prognosis in hepatocellular carcinoma, partly by promoting proliferation through enhanced glucose metabolism. | ||||||||||
| Author: | Li, Yaoqing|Lu, Zhongtang|Liang, Zheyong|Ji, Dong|Zhang, Pengfei|Liu, Qingguang|Zheng, Xin|Yao, Yingmin | ||||||||||
| PMID: | 25738944 | ||||||||||
| 8. | |||||||||||
| Journal: | Nanoscale. 2015 Sep 7;7(33):13907-17. | ||||||||||
| Title: | Mitochondria-acting hexokinase II peptides carried by short-length carbon nanotubes with increased cellular uptake, endosomal evasion, and enhanced bioactivity against cancer cells. | ||||||||||
| Author: | Yoong, Sia Lee|Lau, Wei Liang|Liu, Ang Yu|Prendergast, D'Arcy|Ho, Han Kiat|Yu, Victor Chun Kong|Lee, Chengkuo|Ang, Wee Han|Pastorin, Giorgia | ||||||||||
| PMID: | 26219542 | ||||||||||
| 9. | |||||||||||
| Journal: | Oncotarget. 2015 Sep 22;6(28):26161-76. | ||||||||||
| Title: | Tumor suppressor NDRG2 inhibits glycolysis and glutaminolysis in colorectal cancer cells by repressing c-Myc expression. | ||||||||||
| Author: | Xu, Xinyuan|Li, Jianying|Sun, Xiang|Guo, Yan|Chu, Dake|Wei, Li|Li, Xia|Yang, Guodong|Liu, Xinping|Yao, Libo|Zhang, Jian|Shen, Lan | ||||||||||
| PMID: | 26317652 | ||||||||||
| 10. | |||||||||||
| Journal: | Biofizika. 2015 Nov-Dec;60(6):1050-6. | ||||||||||
| Title: | [Evaluation of Gene Expression of Hexokinases in Colorectal Cancer with the Use of Bioinformatics Methods]. | ||||||||||
| Author: | Krasnov, G S|Dmitriev, A A|Sadtritdinova, A F|Fedorova, M S|Snezhkina, A V|Melnikova, N V|Poteryakhina, A V|Nyushko, K M|Belyakov, M M|Kaprin, A D|Zaretsky, A R|Kudryavtseva, A V | ||||||||||
| PMID: | 26855992 | ||||||||||
| 11. | |||||||||||
| Journal: | PLoS One. 2016 Nov 8;11(11):e0166230. | ||||||||||
| Title: | Prognostic Significance of the Metabolic Marker Hexokinase-2 in Various Solid Tumors: A Meta-Analysis. | ||||||||||
| Author: | Liu, Yulin|Wu, Ke|Shi, Liang|Xiang, Fan|Tao, Kaixiong|Wang, Guobin | ||||||||||
| PMID: | 27824926 | ||||||||||
| 12. | |||||||||||
| Journal: | BMC Genet. 2016 Dec 22;17(Suppl 3):156. | ||||||||||
| Title: | Effect of lentivirus-mediated shRNA inactivation of HK1, HK2, and HK3 genes in colorectal cancer and melanoma cells. | ||||||||||
| Author: | Kudryavtseva, Anna V|Fedorova, Maria S|Zhavoronkov, Alex|Moskalev, Alexey A|Zasedatelev, Alexander S|Dmitriev, Alexey A|Sadritdinova, Asiya F|Karpova, Irina Y|Nyushko, Kirill M|Kalinin, Dmitry V|Volchenko, Nadezhda N|Melnikova, Nataliya V|Klimina, Kseniya | ||||||||||
| PMID: | 28105937 | ||||||||||
| 13. | |||||||||||
| Journal: | Mol Cancer Res. 2016 Sep;14(9):830-40. | ||||||||||
| Title: | Gas1 Inhibits Metastatic and Metabolic Phenotypes in Colorectal Carcinoma. | ||||||||||
| Author: | Li, Qingguo|Qin, Yi|Wei, Ping|Lian, Peng|Li, Yaqi|Xu, Ye|Li, Xinxiang|Li, Dawei|Cai, Sanjun | ||||||||||
| PMID: | 27401611 | ||||||||||
| 14. | |||||||||||
| Journal: | Mol Pharm. 2016 Jul 5;13(7):2497-506. | ||||||||||
| Title: | Dynamic Contrast Enhanced MRI Assessing the Antiangiogenic Effect of Silencing HIF-1alpha with Targeted Multifunctional ECO/siRNA Nanoparticles. | ||||||||||
| Author: | Malamas, Anthony S|Jin, Erlei|Gujrati, Maneesh|Lu, Zheng-Rong | ||||||||||
| PMID: | 27264671 | ||||||||||
| 15. | |||||||||||
| Journal: | Biosci Rep. 2016 Jan 6;36(1):e00299. | ||||||||||
| Title: | The effect of 3-bromopyruvate on human colorectal cancer cells is dependent on glucose concentration but not hexokinase II expression. | ||||||||||
| Author: | Ho, Nelson|Morrison, Jodi|Silva, Andreza|Coomber, Brenda L | ||||||||||
| PMID: | 26740252 | ||||||||||
| 16. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2016 Jan 1;469(1):37-43. | ||||||||||
| Title: | miR-4458 suppresses glycolysis and lactate production by directly targeting hexokinase2 in colon cancer cells. | ||||||||||
| Author: | Qin, Yaguang|Cheng, Chuanyao|Lu, Hong|Wang, Yaqiu | ||||||||||
| PMID: | 26607110 | ||||||||||
| 17. | |||||||||||
| Journal: | Histol Histopathol. 2017 Apr;32(4):351-360. | ||||||||||
| Title: | Hexokinase 2 in colorectal cancer: a potent prognostic factor associated with glycolysis, proliferation and migration. | ||||||||||
| Author: | Katagiri, Munetoshi|Karasawa, Hideaki|Takagi, Kiyoshi|Nakayama, Shun|Yabuuchi, Shinichi|Fujishima, Fumiyoshi|Naitoh, Takeshi|Watanabe, Mika|Suzuki, Takashi|Unno, Michiaki|Sasano, Hironobu | ||||||||||
| PMID: | 27363977 | ||||||||||
| 18. | |||||||||||
| Journal: | Biochem Pharmacol. 2017 Feb 1;125:12-25. | ||||||||||
| Title: | Gen-27, a newly synthesized flavonoid, inhibits glycolysis and induces cell apoptosis via suppression of hexokinase II in human breast cancer cells. | ||||||||||
| Author: | Tao, Lei|Wei, Libing|Liu, Yishi|Ding, Yang|Liu, Xiuting|Zhang, Xin|Wang, Xiaoping|Yao, Yuyuan|Lu, Jinrong|Wang, Qing|Hu, Rong | ||||||||||
| PMID: | 27818240 | ||||||||||
| 19. | |||||||||||
| Journal: | Int J Oncol. 2017 Jan;50(1):161-172. | ||||||||||
| Title: | Metabolic reprogramming and AMPKalpha1 pathway activation by caulerpin in colorectal cancer cells. | ||||||||||
| Author: | Yu, Hua|Zhang, Huiqin|Dong, Mingjun|Wu, Zhou|Shen, Zhonglei|Xie, Yangyang|Kong, Zhenfang|Dai, Xiaoyu|Xu, Binbin | ||||||||||
| PMID: | 27922662 | ||||||||||
| 20. | |||||||||||
| Journal: | Dig Dis Sci. 2017 Mar;62(3):660-668. | ||||||||||
| Title: | MicroRNA-98 Suppress Warburg Effect by Targeting HK2 in Colon Cancer Cells. | ||||||||||
| Author: | Zhu, Weimin|Huang, Yijiao|Pan, Qi|Xiang, Pei|Xie, Nanlan|Yu, Hao | ||||||||||
| PMID: | 28025745 | ||||||||||
| 21. | |||||||||||
| Journal: | Cell Death Discov. 2017 Jan 23;3:16103. | ||||||||||
| Title: | PHLPP regulates hexokinase 2-dependent glucose metabolism in colon cancer cells. | ||||||||||
| Author: | Xiong, Xiaopeng|Wen, Yang-An|Mitov, Mihail I|C Oaks, Mary|Miyamoto, Shigeki|Gao, Tianyan | ||||||||||
| PMID: | 28179998 | ||||||||||
| 22. | |||||||||||
| Journal: | Oncotarget. 2017 May 9;8(19):32332-32344. | ||||||||||
| Title: | Poor prognosis of hexokinase 2 overexpression in solid tumors of digestive system: a meta-analysis. | ||||||||||
| Author: | Wu, Jiayuan|Hu, Liren|Wu, Fenping|Zou, Lei|He, Taiping | ||||||||||
| PMID: | 28415659 | ||||||||||
| 23. | |||||||||||
| Journal: | Cell Death Dis. 2017 May 4;8(5):e2761. | ||||||||||
| Title: | MiR-1 suppresses tumor cell proliferation in colorectal cancer by inhibition of Smad3-mediated tumor glycolysis. | ||||||||||
| Author: | Xu, Wanfu|Zhang, Zijing|Zou, Kejian|Cheng, Yang|Yang, Min|Chen, Huan|Wang, Hongli|Zhao, Junhong|Chen, Peiyu|He, Liying|Chen, Xinwen|Geng, Lanlan|Gong, Sitang | ||||||||||
| PMID: | 28471448 | ||||||||||
| 24. | |||||||||||
| Journal: | Int J Oncol. 2017 Oct;51(4):1271-1279. | ||||||||||
| Title: | PRL-3 improves colorectal cancer cell proliferation and invasion through IL-8 mediated glycolysis metabolism. | ||||||||||
| Author: | Xu, Heyang|Zeng, Yujie|Liu, Lu|Gao, Qian|Jin, Shaowen|Lan, Qiusheng|Lai, Wei|Luo, Xingxi|Wu, Heng|Huang, Yongliang|Chu, Zhonghua | ||||||||||
| PMID: | 28791350 | ||||||||||
| 25. | |||||||||||
| Journal: | Theranostics. 2018 Feb 2;8(5):1376-1388. | ||||||||||
| Title: | Cancer-associated fibroblasts enhance tumor (18)F-FDG uptake and contribute to the intratumor heterogeneity of PET-CT. | ||||||||||
| Author: | Shangguan, Chengfang|Gan, Guifang|Zhang, Jieying|Wu, Jinliang|Miao, Ying|Zhang, Miao|Li, Biao|Mi, Jun | ||||||||||
| PMID: | 29507627 | ||||||||||
| 26. | |||||||||||
| Journal: | Oncol Rep. 2018 May;39(5):2436-2442. | ||||||||||
| Title: | Berberine decelerates glucose metabolism via suppression of mTORdependent HIF1alpha protein synthesis in colon cancer cells. | ||||||||||
| Author: | Mao, Liyuan|Chen, Qiongyun|Gong, Ke|Xu, Xiaolin|Xie, Yurou|Zhang, Wenqing|Cao, Hanwei|Hu, Tianhui|Hong, Xiaoting|Zhan, Yan-Yan | ||||||||||
| PMID: | 29565467 | ||||||||||
| 27. | |||||||||||
| Journal: | Mol Biol (Mosk). 2018 Mar-Apr;52(2):220-230. | ||||||||||
| Title: | [Overexpression of microRNAs miR-9, -98, and -199 Correlates with the Downregulation of HK2 Expression in Colorectal Cancer]. | ||||||||||
| Author: | Snezhkina, A V|Krasnov, G S|Zhikrivetskaya, S O|Karpova, I Y|Fedorova, M S|Nyushko, K M|Belyakov, M M|Gnuchev, N V|Sidorov, D V|Alekseev, B Y|Melnikova, N V|Kudryavtseva, A V | ||||||||||
| PMID: | 29695690 | ||||||||||
| 28. | |||||||||||
| Journal: | Biosci Rep. 2018 Jul 2;38(4). pii: BSR20180580. | ||||||||||
| Title: | Chemokine (C-X-C motif) ligand 1 is associated with tumor progression and poor prognosis in patients with colorectal cancer. | ||||||||||
| Author: | Zhuo, Changhua|Wu, Xianyi|Li, Jing|Hu, Dan|Jian, Jinliang|Chen, Changjiang|Zheng, Xiongwei|Yang, Chunkang | ||||||||||
| PMID: | 29784873 | ||||||||||