Primary Site >> Colorectal Cancer
Gene >> HK2
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Ref: Molecular mechanism underlying the detection of colorectal cancer by 18F-2-fluoro-2-deoxy-D-glucose positron emission tomography. PMID: 22065316 Ref: MicroRNA-143 down-regulates Hexokinase 2 in colon cancer cells. PMID: 22691140 |
Ref: Wogonin reverses hypoxia resistance of human colon cancer HCT116 cells via downregulation of HIF-1alpha and glycolysis, by inhibiting PI3K/Akt signaling pathway. PMID: 23761018 Ref: Combined evaluation of hexokinase 2 and phosphorylated pyruvate dehydrogenase-E1alpha in invasive front lesions of colorectal tumors predicts cancer metabolism and patient prognosis. PMID: 25060325 Ref: Regulation of 18F-FDG accumulation in colorectal cancer cells with mutated KRAS. PMID: 25453050 |
Ref: Curcumin inhibits aerobic glycolysis and induces mitochondrial-mediated apoptosis through hexokinase II in human colorectal cancer cells in vitro. PMID: 25229889 Ref: Metastasis-associated in colon cancer-1 is associated with poor prognosis in hepatocellular carcinoma, partly by promoting proliferation through enhanced glucose metabolism. PMID: 25738944 Ref: Mitochondria-acting hexokinase II peptides carried by short-length carbon nanotubes with increased cellular uptake, endosomal evasion, and enhanced bioactivity against cancer cells. PMID: 26219542 Ref: Tumor suppressor NDRG2 inhibits glycolysis and glutaminolysis in colorectal cancer cells by repressing c-Myc expression. PMID: 26317652 Ref: [Evaluation of Gene Expression of Hexokinases in Colorectal Cancer with the Use of Bioinformatics Methods]. PMID: 26855992 |
Ref: miR-4458 suppresses glycolysis and lactate production by directly targeting hexokinase2 in colon cancer cells. PMID: 26607110 Ref: The effect of 3-bromopyruvate on human colorectal cancer cells is dependent on glucose concentration but not hexokinase II expression. PMID: 26740252 Ref: Dynamic Contrast Enhanced MRI Assessing the Antiangiogenic Effect of Silencing HIF-1alpha with Targeted Multifunctional ECO/siRNA Nanoparticles. PMID: 27264671 Ref: Gas1 Inhibits Metastatic and Metabolic Phenotypes in Colorectal Carcinoma. PMID: 27401611 Ref: Prognostic Significance of the Metabolic Marker Hexokinase-2 in Various Solid Tumors: A Meta-Analysis. PMID: 27824926 Ref: Effect of lentivirus-mediated shRNA inactivation of HK1, HK2, and HK3 genes in colorectal cancer and melanoma cells. PMID: 28105937 |
Ref: Hexokinase 2 in colorectal cancer: a potent prognostic factor associated with glycolysis, proliferation and migration. PMID: 27363977 Ref: Gen-27, a newly synthesized flavonoid, inhibits glycolysis and induces cell apoptosis via suppression of hexokinase II in human breast cancer cells. PMID: 27818240 Ref: Metabolic reprogramming and AMPKalpha1 pathway activation by caulerpin in colorectal cancer cells. PMID: 27922662 Ref: MicroRNA-98 Suppress Warburg Effect by Targeting HK2 in Colon Cancer Cells. PMID: 28025745 Ref: PHLPP regulates hexokinase 2-dependent glucose metabolism in colon cancer cells. PMID: 28179998 Ref: Poor prognosis of hexokinase 2 overexpression in solid tumors of digestive system: a meta-analysis. PMID: 28415659 Ref: MiR-1 suppresses tumor cell proliferation in colorectal cancer by inhibition of Smad3-mediated tumor glycolysis. PMID: 28471448 Ref: PRL-3 improves colorectal cancer cell proliferation and invasion through IL-8 mediated glycolysis metabolism. PMID: 28791350 |
Ref: Cancer-associated fibroblasts enhance tumor (18)F-FDG uptake and contribute to the intratumor heterogeneity of PET-CT. PMID: 29507627 Ref: Berberine decelerates glucose metabolism via suppression of mTORdependent HIF1alpha protein synthesis in colon cancer cells. PMID: 29565467 Ref: [Overexpression of microRNAs miR-9, -98, and -199 Correlates with the Downregulation of HK2 Expression in Colorectal Cancer]. PMID: 29695690 Ref: Chemokine (C-X-C motif) ligand 1 is associated with tumor progression and poor prognosis in patients with colorectal cancer. PMID: 29784873 |