Primary Site >> Stomach Cancer

Gene >> HIF1A

Journal: J Natl Cancer Inst. 2003 Apr 2;95(7):516-25.
Title: YC-1: a potential anticancer drug targeting hypoxia-inducible factor 1.
Author: Yeo, Eun-Jin|Chun, Yang-Sook|Cho, Young-Suk|Kim, Jinho|Lee, June-Chul|Kim, Myung-Suk|Park, Jong-Wan
PMID: 12671019
Journal: Zhonghua Yi Xue Za Zhi. 2004 Feb 17;84(4):306-11.
Title: [The overexpression and significance of MKP-1 in oxygen-deprived gastric cancer cell line SGC7901].
Author: Liu, Chang-jiang|Shi, Yong-quan|Han, Zhe-yi|Xue, Yan|Pan, Yang-lin|Shen, Hui-qin|Du, Jing-ping|Han, Shuang|Qiao, Tai-dong|Fan, Dai-ming
PMID: 15059515
Journal: J Natl Cancer Inst. 2004 Jun 16;96(12):946-56.
Title: Role of hypoxia-inducible factor 1alpha in gastric cancer cell growth, angiogenesis, and vessel maturation.
Author: Stoeltzing, Oliver|McCarty, Marya F|Wey, Jane S|Fan, Fan|Liu, Wenbiao|Belcheva, Anna|Bucana, Corazon D|Semenza, Gregg L|Ellis, Lee M
PMID: 15199114
Journal: Zhonghua Zhong Liu Za Zhi. 2004 Sep;26(9):517-20.
Title: [Expressions and activities of Rho GTPases in hypoxia and its relationship with tumor angiogenesis].
Author: Xue, Yan|Bi, Feng|Liu, Wen-chao|Pan, Yang-lin|Han, Zhe-yi|Liu, Na|Liu, Chang-jiang|Shen, Hui-qin|Zhang, Xue-yong
PMID: 15555278
Journal: Cancer Biol Ther. 2005 Jan;4(1):113-7. Epub 2005 Jan 8.
Title: Inhibition of gastric cancer angiogenesis by vector-based RNA interference for Raf-1.
Author: Meng, Fanping|Ding, Jie|Liu, Na|Zhang, Jing|Shao, Xiaodong|Shen, Huiqin|Xue, Yan|Xie, Huahong|Fan, Daiming
PMID: 15662129
Journal: J Biomed Sci. 2005;12(1):229-41.
Title: Cyclooxygenase-2 increases hypoxia-inducible factor-1 and vascular endothelial growth factor to promote angiogenesis in gastric carcinoma.
Author: Huang, Shih-Pei|Wu, Ming-Shiang|Shun, Chia-Tung|Wang, Hsiu-Po|Hsieh, Chang-Yao|Kuo, Min-Liang|Lin, Jaw-Town
PMID: 15864753
Journal: Eur J Cancer. 2005 Dec;41(18):2792-805. Epub 2005 Nov 14.
Title: Is the hypoxia-inducible factor pathway important in gastric cancer?
Author: Griffiths, E A|Pritchard, S A|Welch, I M|Price, P M|West, C M
PMID: 16290133
Journal: Cancer Lett. 2006 Oct 8;242(1):20-7.
Title: Celecoxib could reverse the hypoxia-induced Angiopoietin-2 upregulation in gastric cancer.
Author: Wang, Jun|Wu, Kaichun|Bai, Feihu|Zhai, Huihong|Xie, Huahong|Du, Yulei|Liang, Jie|Han, Shuang|Chen, Yu|Lin, Tao|Fan, Daiming
PMID: 16338068
Journal: Int J Cancer. 2006 Jun 15;118(12):2965-72.
Title: Role of Rac1 and Cdc42 in hypoxia induced p53 and von Hippel-Lindau suppression and HIF1alpha activation.
Author: Xue, Yan|Bi, Feng|Zhang, Xueyong|Zhang, Siyuan|Pan, Yanglin|Liu, Na|Shi, Yongquan|Yao, Xuebiao|Zheng, Yi|Fan, Daiming
PMID: 16395716
Journal: Gastric Cancer. 2006;9(1):44-9.
Title: Overexpression of hypoxia-inducible factor-1 alpha in gastric adenocarcinoma.
Author: Urano, Naomi|Fujiwara, Yoshiyuki|Doki, Yuichirou|Tsujie, Masaki|Yamamoto, Hirofumi|Miyata, Hiroshi|Takiguchi, Shuji|Yasuda, Takushi|Yano, Masahiko|Monden, Morito
PMID: 16557436
Journal: Pathobiology. 2006;73(1):8-17.
Title: Significance of Akt phosphorylation on tumor growth and vascular endothelial growth factor expression in human gastric carcinoma.
Author: Kobayashi, Iwao|Semba, Shuho|Matsuda, Yoshiko|Kuroda, Yoshikazu|Yokozaki, Hiroshi
PMID: 16785763
Journal: J Surg Oncol. 2006 Aug 1;94(2):149-54.
Title: Clinicopathologic significance of hypoxia-inducible factor 1alpha overexpression in gastric carcinomas.
Author: Mizokami, Ken|Kakeji, Yoshihiro|Oda, Shinya|Irie, Koji|Yonemura, Tomohiro|Konishi, Fumio|Maehara, Yoshihiko
PMID: 16847924
Journal: Int J Oncol. 2006 Sep;29(3):549-55.
Title: CoCl2-induced HIF-1alpha expression correlates with proliferation and apoptosis in MKN-1 cells: a possible role for the PI3K/Akt pathway.
Author: Ardyanto, Tonang Dwi|Osaki, Mitsuhiko|Tokuyasu, Naruo|Nagahama, Yumi|Ito, Hisao
PMID: 16865270
Journal: J Nat Prod. 2006 Jul;69(7):1095-7.
Title: Phenanthroquinolizidine alkaloids from the roots of Boehmeria pannosa potently inhibit hypoxia-inducible factor-1 in AGS human gastric cancer cells.
Author: Cai, Xing Fu|Jin, Xuejun|Lee, Dongho|Yang, Young Taek|Lee, Kyeong|Hong, Young-Soo|Lee, Jeong-Hyung|Lee, Jung Joon
PMID: 16872154
Journal: Clin Cancer Res. 2006 Sep 1;12(17):5112-7.
Title: Overexpression of hypoxia-inducible factor 1alpha and p53 is a marker for an unfavorable prognosis in gastric cancer.
Author: Sumiyoshi, Yasushi|Kakeji, Yoshihiro|Egashira, Akinori|Mizokami, Ken|Orita, Hiroyuki|Maehara, Yoshihiko
PMID: 16951228
Journal: Anticancer Res. 2006 Sep-Oct;26(5B):3849-53.
Title: Up-regulation of hypoxia-inducible factor-1 alpha and VEGF mRNAs in peritoneal dissemination of patients with gastric cancer.
Author: Yoshikawa, Takaki|Tsuburaya, Akira|Miyagi, Yohei|Sekiguchi, Hironobu|Kimura, Masayuki|Cho, Haruhiko|Kobayashi, Osamu
PMID: 17094412
Journal: Ai Zheng. 2006 Nov;25(11):1439-42.
Title: [Expression and clinical significance of hypoxia-inducible factor-1alpha in gastric cancer].
Author: Han, Bing|Xu, Rui-Hua|Shi, Yan-Xia|Li, Yu-Hong|Luo, Hui-Yan|Wang, Feng|Hou, Jing-Hui|Cai, Mu-Yan|Jiang, Wen-Qi
PMID: 17094917
Journal: Acta Biochim Pol. 2006;53(4):789-99. Epub 2006 Dec 4.
Title: Hypoxic regulation of PFKFB-3 and PFKFB-4 gene expression in gastric and pancreatic cancer cell lines and expression of PFKFB genes in gastric cancers.
Author: Bobarykina, Anastasiya Y|Minchenko, Dmytro O|Opentanova, Iryna L|Moenner, Michel|Caro, Jaime|Esumi, Hiroyasu|Minchenko, Oleksandr H
PMID: 17143338
Journal: World J Surg Oncol. 2006 Dec 13;4:94.
Title: Relationship of hypoxia-inducible factor 1alpha and p21WAF1/CIP1 expression to cell apoptosis and clinical outcome in patients with gastric cancer.
Author: Mizokami, Ken|Kakeji, Yoshihiro|Oda, Shinya|Maehara, Yoshihiko
PMID: 17166265
Journal: Int J Cancer. 2007 Apr 15;120(8):1803-10.
Title: Mammalian target of rapamycin is activated in human gastric cancer and serves as a target for therapy in an experimental model.
Author: Lang, Sven A|Gaumann, Andreas|Koehl, Gudrun E|Seidel, Ulrike|Bataille, Frauke|Klein, Dagmar|Ellis, Lee M|Bolder, Ulrich|Hofstaedter, Ferdinand|Schlitt, Hans-Jurgen|Geissler, Edward K|Stoeltzing, Oliver
PMID: 17230506
Journal: Exp Cell Res. 2007 Apr 1;313(6):1181-91. Epub 2007 Feb 2.
Title: Hypoxia-inducible factor 1alpha regulates lung adenocarcinoma cell invasion.
Author: Shyu, Kou-Gi|Hsu, Feng-Lin|Wang, Ming Jen|Wang, Bao-Wei|Lin, Shankung
PMID: 17335808
Journal: Mol Cancer Ther. 2007 Mar;6(3):1123-32.
Title: Inhibition of heat shock protein 90 impairs epidermal growth factor-mediated signaling in gastric cancer cells and reduces tumor growth and vascularization in vivo.
Author: Lang, Sven A|Klein, Dagmar|Moser, Christian|Gaumann, Andreas|Glockzin, Gabriel|Dahlke, Marc H|Dietmaier, Wolfgang|Bolder, Ulrich|Schlitt, Hans J|Geissler, Edward K|Stoeltzing, Oliver
PMID: 17363505
Journal: World J Gastroenterol. 2007 Mar 21;13(11):1680-6.
Title: Upregulation of hypoxia inducible factor 1alpha mRNA is associated with elevated vascular endothelial growth factor expression and excessive angiogenesis and predicts a poor prognosis in gastric carcinoma.
Author: Ma, Jie|Zhang, Li|Ru, Guo-Qing|Zhao, Zhong-Sheng|Xu, Wen-Juan
PMID: 17461470
Journal: Mol Cell Biochem. 2007 Sep;303(1-2):151-60.
Title: Involvement of MGr1-Ag/37LRP in the vincristine-induced HIF-1 expression in gastric cancer cells.
Author: Liu, Lili|Ning, Xiaoxuan|Sun, Li|Shi, Yongquan|Han, Shuang|Guo, Changcun|Chen, Yu|Sun, Shiren|Yin, Fang|Wu, Kaichun|Fan, Daiming
PMID: 17476462
Journal: Tumour Biol. 2007;28(3):173-80.
Title: KCl depolarization increases HIF-1 transcriptional activity via the calcium-independent pathway in SGC7901 gastric cancer cells.
Author: Lan, Mei|Shi, Yongquan|Sun, Li|Liu, Lili|Guo, Xueyan|Lu, Yuanyuan|Wang, Jun|Liang, Jie|Fan, Daiming
PMID: 17519536
Journal: J Natl Cancer Inst. 2007 Jun 20;99(12):949-61.
Title: Structural basis for depletion of heat shock protein 90 client proteins by deguelin.
Author: Oh, Seung Hyun|Woo, Jong Kyu|Yazici, Yasemin Dakak|Myers, Jeffrey N|Kim, Woo-Young|Jin, Quanri|Hong, Soon Sun|Park, Hyun-Ju|Suh, Young-Ger|Kim, Kyu-Won|Hong, Waun Ki|Lee, Ho-Young
PMID: 17565155
Journal: J Nat Prod. 2007 Jul;70(7):1093-7.
Title: Abietane diterpenes from Salvia miltiorrhiza inhibit the activation of hypoxia-inducible factor-1.
Author: Dat, Nguyen Tien|Jin, Xuejun|Lee, Jeong-Hyung|Lee, Dongho|Hong, Young-Soo|Lee, Kyeong|Kim, Young Ho|Lee, Jung Joon
PMID: 17583950
Journal: Zhonghua Wai Ke Za Zhi. 2007 Jul 1;45(13):905-8.
Title: [Expressions of hypoxia inducible factor-1alpha and insulin-like growth factor-II in gastric carcinoma: correlation with angiogenesis and prognosis].
Author: Ru, Guo-Qing|Zhao, Zhong-Sheng|Tang, Qi-le|Xu, Wen-Juan
PMID: 17953839
Journal: Oncology. 2007;72(1-2):111-7. Epub 2007 Nov 15.
Title: Vascular endothelial growth factor, hypoxia-inducible factor 1 alpha and CD34 expressions in early-stage gastric tumors: relationship with pathological factors and prognostic impact on survival.
Author: Cabuk, Devrim|Basaran, Gul|Celikel, Cigdem|Dane, Faysal|Yumuk, P Fulden|Iyikesici, M Salih|Ekenel, Meltem|Turhal, N Serdar
PMID: 18025805
Journal: Mol Cancer Ther. 2007 Dec;6(12 Pt 1):3297-306.
Title: Kallikrein-binding protein inhibits growth of gastric carcinoma by reducing vascular endothelial growth factor production and angiogenesis.
Author: Zhu, Baohe|Lu, Lei|Cai, Weibin|Yang, Xia|Li, Chaoyang|Yang, Zhonghan|Zhan, Wenhua|Ma, Jian-Xing|Gao, Guoquan
PMID: 18089723
Journal: Cancer Sci. 2008 Jan;99(1):121-8. Epub 2007 Oct 22.
Title: Hypoxia-inducible factor-1 alpha contributes to hypoxia-induced chemoresistance in gastric cancer.
Author: Liu, Lili|Ning, Xiaoxuan|Sun, Li|Zhang, Hongbo|Shi, Yongquan|Guo, Changcun|Han, Shuang|Liu, Jie|Sun, Shiren|Han, Zheyi|Wu, Kaichun|Fan, Daiming
PMID: 17953712
Journal: Carcinogenesis. 2008 Jan;29(1):44-51.
Title: A hypoxia-independent up-regulation of hypoxia-inducible factor-1 by AKT contributes to angiogenesis in human gastric cancer.
Author: Lee, Byung Lan|Kim, Woo Ho|Jung, Jieun|Cho, Sung Jin|Park, Jong-Wan|Kim, Jihyen|Chung, Hee-Yong|Chang, Mee Soo|Nam, Seon Young
PMID: 17984117
Journal: Oncol Rep. 2008 Feb;19(2):339-43.
Title: Down-regulation of cobalt-induced HIF-1alpha expression correlates with cell proliferation and apoptosis in human gastric carcinoma cells.
Author: Ardyanto, Tonang Dwi|Osaki, Mitsuhiko|Nagahama, Yumi|Yamaga, Kensaku|Maeta, Noritaka|Tamura, Takayuki|Ito, Hisao
PMID: 18202779
Journal: BMC Cancer. 2008 May 1;8:123.
Title: Clinicopathologic significance of HIF-1alpha, p53, and VEGF expression and preoperative serum VEGF level in gastric cancer.
Author: Oh, Sung Yong|Kwon, Hyuk-Chan|Kim, Sung-Hyun|Jang, Jin Seok|Kim, Min Chan|Kim, Kyeong Hee|Han, Jin-Yeong|Kim, Chung Ock|Kim, Su-Jin|Jeong, Jin-sook|Kim, Hyo-Jin
PMID: 18452596
Journal: Ann Surg Oncol. 2008 Aug;15(8):2336-44.
Title: Lactate dehydrogenase-5 (LDH-5) expression in human gastric cancer: association with hypoxia-inducible factor (HIF-1alpha) pathway, angiogenic factors production and poor prognosis.
Author: Kolev, Yanislav|Uetake, Hiroyuki|Takagi, Yoko|Sugihara, Kenichi
PMID: 18521687
Journal: Cancer Biol Ther. 2008 Sep;7(9):1377-85. Epub 2008 Sep 2.
Title: Everolimus (RAD001) and anti-angiogenic cyclophosphamide show long-term control of gastric cancer growth in vivo.
Author: Cejka, Daniel|Preusser, Matthias|Woehrer, Adelheid|Sieghart, Wolfgang|Strommer, Sabine|Werzowa, Johannes|Fuereder, Thorsten|Wacheck, Volker
PMID: 18708754
Journal: Cancer Res. 2008 Dec 15;68(24):10113-20.
Title: Hypoxia-inducible factor 1alpha mediates anoikis resistance via suppression of alpha5 integrin.
Author: Rohwer, Nadine|Welzel, Martina|Daskalow, Katjana|Pfander, David|Wiedenmann, Bertram|Detjen, Katharina|Cramer, Thorsten
PMID: 19074877
Journal: Anticancer Res. 2008 Nov-Dec;28(6A):3801-8.
Title: mTOR inhibition sensitizes gastric cancer to alkylating chemotherapy in vivo.
Author: Cejka, Daniel|Preusser, Matthias|Fuereder, Thorsten|Sieghart, Wolfgang|Werzowa, Johannes|Strommer, Sabine|Wacheck, Volker
PMID: 19189667
Journal: Mol Cell Proteomics. 2009 Jan;8(1):70-85.
Title: Mechanism of cancer cell adaptation to metabolic stress: proteomics identification of a novel thyroid hormone-mediated gastric carcinogenic signaling pathway.
Author: Liu, Rui|Li, Zhenjun|Bai, Shujun|Zhang, Haiyuan|Tang, Minghai|Lei, Yunlong|Chen, Lijuan|Liang, Shufang|Zhao, Ying-Lan|Wei, Yuquan|Huang, Canhua
PMID: 18723843
Journal: Cancer Biol Ther. 2009 Jan;8(2):174-9. Epub 2009 Feb 17.
Title: RNAi-mediated inhibition of Raf-1 leads to decreased angiogenesis and tumor growth in gastric cancer.
Author: Meng, Fanping|Dong, Baoxia|Li, Hanwei|Fan, Daiming|Ding, Jie
PMID: 19029826
Journal: Clin Exp Med. 2009 Jun;9(2):139-47.
Title: Effects of HIF-1alpha on human gastric cancer cell apoptosis at different CO(2) pressures.
Author: Hao, Ying-Xue|Zhong, Hua|Yu, Pei-Wu|Zhang, Chao|Zeng, Dong-Zhu|Shi, Yan|Tang, Bo
PMID: 19048182
Journal: Br J Cancer. 2009 Mar 10;100(5):772-81.
Title: HIF-1alpha determines the metastatic potential of gastric cancer cells.
Author: Rohwer, N|Lobitz, S|Daskalow, K|Jons, T|Vieth, M|Schlag, P M|Kemmner, W|Wiedenmann, B|Cramer, T|Hocker, M
PMID: 19223895
Journal: Exp Mol Med. 2009 Jan 31;41(1):51-8.
Title: Regulation of glucose metabolism-related genes and VEGF by HIF-1alpha and HIF-1beta, but not HIF-2alpha, in gastric cancer.
Author: Song, In Sung|Wang, Ai Guo|Yoon, Sun Young|Kim, Jeong Min|Kim, Joo Heon|Lee, Dong Seok|Kim, Nam Soon
PMID: 19287200
Journal: Int J Oncol. 2009 Jun;34(6):1737-42.
Title: Integrative genomic analyses of ZEB2: Transcriptional regulation of ZEB2 based on SMADs, ETS1, HIF1alpha, POU/OCT, and NF-kappaB.
Author: Katoh, Masuko|Katoh, Masaru
PMID: 19424592
Journal: Biochem Genet. 2009 Oct;47(9-10):625-34.
Title: Association of the hypoxia inducible factor-1alpha gene polymorphisms with gastric cancer in Tibetans.
Author: Li, Kang|Zhang, Yali|Dan, Zeng|Wang, Yi|Ren, Zhuoma Ci
PMID: 19504235
Journal: J Biol Regul Homeost Agents. 2009 Apr-Jun;23(2):71-8.
Title: Radiosensitization effect of luteolin on human gastric cancer SGC-7901 cells.
Author: Zhang, Q|Wan, L|Guo, Y|Cheng, N|Cheng, W|Sun, Q|Zhu, J
PMID: 19589287
Journal: J Cell Mol Med. 2009 Aug;13(8B):1706-18.
Title: Osteopontin promotes gastric cancer metastasis by augmenting cell survival and invasion through Akt-mediated HIF-1alpha up-regulation and MMP9 activation.
Author: Song, Gang|Ouyang, Gaoliang|Mao, Yubin|Ming, Yanlin|Bao, Shideng|Hu, Tianhui
PMID: 19602039
Journal: Oncol Rep. 2009 Oct;22(4):693-9.
Title: Hypoxia-inducible factor-1alpha expression predicts the response to 5-fluorouracil-based adjuvant chemotherapy in advanced gastric cancer.
Author: Nakamura, Jun|Kitajima, Yoshihiko|Kai, Keita|Mitsuno, Mayumi|Ide, Takao|Hashiguchi, Kazuyoshi|Hiraki, Masatsugu|Miyazaki, Kohji
PMID: 19724845
Journal: Cancer Res. 2009 Sep 15;69(18):7160-4.
Title: mTOR signal and hypoxia-inducible factor-1 alpha regulate CD133 expression in cancer cells.
Author: Matsumoto, Kazuko|Arao, Tokuzo|Tanaka, Kaoru|Kaneda, Hiroyasu|Kudo, Kanae|Fujita, Yoshihiko|Tamura, Daisuke|Aomatsu, Keiichi|Tamura, Tomohide|Yamada, Yasuhide|Saijo, Nagahiro|Nishio, Kazuto
PMID: 19738050
Journal: Zhonghua Wei Chang Wai Ke Za Zhi. 2009 Sep;12(5):498-501.
Title: [Relationship between the expression of hypoxia-inducible factor-1alpha and chemotherapy response in gastric carcinoma].
Author: Wu, Qing|Li, Zhao-shen|Li, Da-wei|Peng, Zhi-hai|Yang, Zhao-rui
PMID: 19742344
Journal: APMIS. 2009 Dec;117(12):880-5.
Title: Mutational analysis of hypoxia-related genes HIF1alpha and CUL2 in common human cancers.
Author: Park, Sang Wook|Chung, Nak Gyun|Hur, Soo Young|Kim, Ho Shik|Yoo, Nam Jin|Lee, Sug Hyung
PMID: 20078552
Journal: Gut Liver. 2009 Jun;3(2):88-94.
Title: The clinicopathological significance of tissue levels of hypoxia-inducible factor-1alpha and vascular endothelial growth factor in gastric cancer.
Author: Kim, Seong-Eun|Shim, Ki-Nam|Jung, Sung-Ae|Yoo, Kwon|Lee, Joo Ho
PMID: 20431729
Journal: Biomaterials. 2010 Mar;31(8):2302-12.
Title: Anti-HIF-1alpha antibody-conjugated pluronic triblock copolymers encapsulated with Paclitaxel for tumor targeting therapy.
Author: Song, Hua|He, Rong|Wang, Kan|Ruan, Jing|Bao, Chenchen|Li, Na|Ji, Jiajia|Cui, Daxiang
PMID: 20004970
Journal: Int J Cancer. 2010 Sep 1;127(5):1158-71.
Title: HIF-1alpha is an unfavorable determinant of relapse in gastric cancer patients who underwent curative surgery followed by adjuvant 5-FU chemotherapy.
Author: Nakamura, Jun|Kitajima, Yoshihiko|Kai, Keita|Hashiguchi, Kazuyoshi|Hiraki, Masatsugu|Noshiro, Hirokazu|Miyazaki, Kohji
PMID: 20020496
Journal: Int J Oncol. 2010 Feb;36(2):415-20.
Title: Integrative genomic analyses of CXCR4: transcriptional regulation of CXCR4 based on TGFbeta, Nodal, Activin signaling and POU5F1, FOXA2, FOXC2, FOXH1, SOX17, and GFI1 transcription factors.
Author: Katoh, Masuko|Katoh, Masaru
PMID: 20043076
Journal: Sichuan Da Xue Xue Bao Yi Xue Ban. 2010 Jan;41(1):49-52, 76.
Title: [Experimental study of HIF-1alpha antisense oligonucleotide on implanted human gastric cancer in nude mice].
Author: He, Tao|Li, Yong-Hao|Wang, Dian-Dong|Zhang, Hu
PMID: 20369469
Journal: Oncol Rep. 2010 Jun;23(6):1735-45.
Title: Cetuximab enhances the effect of oxaliplatin on hypoxic gastric cancer cell lines.
Author: Luo, Hui-Yan|Wei, Wei|Shi, Yan-Xia|Chen, Xiao-Qin|Li, Yu-Hong|Wang, Feng|Qiu, Miao-Zhen|Li, Fang-Hua|Yan, Shu-Li|Zeng, Mu-Sheng|Huang, Peng|Xu, Rui-Hua
PMID: 20428833
Journal: Toxicology. 2010 Jul-Aug;274(1-3):27-33.
Title: gamma-Tocotrienol modulates the paracrine secretion of VEGF induced by cobalt(II) chloride via ERK signaling pathway in gastric adenocarcinoma SGC-7901 cell line.
Author: Bi, Sheng|Liu, Jia-Ren|Li, Yang|Wang, Qi|Liu, Hui-Kun|Yan, Ya-Geng|Chen, Bing-Qing|Sun, Wen-Guang
PMID: 20452389
Journal: Cancer Biol Ther. 2010 Aug 15;10(4):376-82. Epub 2010 Aug 21.
Title: HIF-1alpha and HIF-2alpha correlate with migration and invasion in gastric cancer.
Author: Wang, Yanxia|Li, Zhichao|Zhang, Hongbo|Jin, Haifeng|Sun, Li|Dong, Haiying|Xu, Min|Zhao, Pengtao|Zhang, Bo|Wang, Jin|Pan, Yanglin|Liu, Lili
PMID: 20559021
Journal: PLoS One. 2010 Aug 10;5(8):e12038.
Title: Hypoxia-inducible factor 1alpha determines gastric cancer chemosensitivity via modulation of p53 and NF-kappaB.
Author: Rohwer, Nadine|Dame, Christof|Haugstetter, Anja|Wiedenmann, Bertram|Detjen, Katharina|Schmitt, Clemens A|Cramer, Thorsten
PMID: 20706634
Journal: Zhonghua Wai Ke Za Zhi. 2010 Jun 1;48(11):847-51.
Title: [Effects of hypoxia-inducible factor-1alpha on human gastric cancer cell apoptosis under in vitro CO(2) pneumoperitoneum environment].
Author: Hao, Ying-xue|Yu, Pei-wu|Zeng, Dong-zhu|Zhao, Yong-liang|Shi, Yan|Rao, Yun|Zhou, Li-xin
PMID: 21163055
Journal: Infect Agent Cancer. 2010 Dec 31;5:27.
Title: Epstein-Barr virus-specific methylation of human genes in gastric cancer cells.
Author: Ryan, Julie L|Jones, Richard J|Kenney, Shannon C|Rivenbark, Ashley G|Tang, Weihua|Knight, Elizabeth Rw|Coleman, William B|Gulley, Margaret L
PMID: 21194482
Journal: Br J Cancer. 2011 Jan 4;104(1):166-74.
Title: A hypoxia-dependent upregulation of hypoxia-inducible factor-1 by nuclear factor-kappaB promotes gastric tumour growth and angiogenesis.
Author: Nam, S Y|Ko, Y S|Jung, J|Yoon, J|Kim, Y H|Choi, Y J|Park, J W|Chang, M S|Kim, W H|Lee, B L
PMID: 21119667
Journal: Cancer Chemother Pharmacol. 2011 Oct;68(4):871-8.
Title: Cetuximab enhances the activities of irinotecan on gastric cancer cell lines through downregulating the EGFR pathway upregulated by irinotecan.
Author: Liu, Xin|Guo, Wei-Jian|Zhang, Xiao-Wei|Cai, Xu|Tian, Shu|Li, Jin
PMID: 21286718
Journal: J Huazhong Univ Sci Technolog Med Sci. 2011 Feb;31(1):52-57.
Title: Establishment and characterization of chronic-hypoxia-resistant gastric cancer cell line MNK45/HYP.
Author: Qiu, Hong|Hu, Guangyuan|Xiong, Huihua
PMID: 21336723
Journal: Oncol Rep. 2011 Sep;26(3):681-6.
Title: Pigment epithelium-derived factor inhibits angiogenesis and growth of gastric carcinoma by down-regulation of VEGF.
Author: Zhang, Yang|Han, Jiande|Yang, Xia|Shao, Chunkui|Xu, Zumin|Cheng, Rui|Cai, Weibin|Ma, Jianxin|Yang, Zhonghan|Gao, Guoquan
PMID: 21617872
Journal: BMC Cancer. 2011 Jun 22;11:264.
Title: Constitutive phosphorylation of the FOXO1 transcription factor in gastric cancer cells correlates with microvessel area and the expressions of angiogenesis-related molecules.
Author: Kim, Sue Youn|Yoon, Jiyeon|Ko, Young San|Chang, Mee Soo|Park, Jong-Wan|Lee, Hee Eun|Kim, Min A|Kim, Ji Hun|Kim, Woo Ho|Lee, Byung Lan
PMID: 21696576
Journal: Sichuan Da Xue Xue Bao Yi Xue Ban. 2011 Jul;42(4):445-50.
Title: [The effect of RhoA and proteasome inhibitor MG132 on angiogenesis in tumors].
Author: Yue, Cai-Xia|Ma, Ji|Zhou, Hai-Jun|Tang, Qiu-Lin|Li, Li-Lan|Bi, Feng|Xue, Yan
PMID: 21866623
Journal: J Endocrinol. 2011 Dec;211(3):249-56.
Title: The effects of recombinant human GH on promoting tumor growth depend on the expression of GH receptor in vivo.
Author: Lin, Yan|Li, Suyi|Cao, Peng|Cheng, Lu|Quan, Ming|Jiang, Suyu
PMID: 21920991
Journal: Biochem Biophys Res Commun. 2011 Nov 18;415(2):348-54.
Title: Transcriptional up-regulation of RhoE by hypoxia-inducible factor (HIF)-1 promotes epithelial to mesenchymal transition of gastric cancer cells during hypoxia.
Author: Zhou, Jinfeng|Li, Kai|Gu, Yong|Feng, Bin|Ren, Gui|Zhang, Liyun|Wang, Yafang|Nie, Yongzhan|Fan, Daiming
PMID: 22037464
Journal: J Gastric Cancer. 2011 Mar;11(1):16-22.
Title: Eupatilin Inhibits Gastric Cancer Cell Growth by Blocking STAT3-Mediated VEGF Expression.
Author: Cheong, Jae-Ho|Hong, Sung Yi|Zheng, Yanjun|Noh, Sung Hoon
PMID: 22076197
Journal: Mol Biol Rep. 2012 Apr;39(4):4127-34.
Title: TFF3 mediated induction of VEGF via hypoxia in human gastric cancer SGC-7901 cells.
Author: Guleng, Bayasi|Han, Jia|Yang, Jin-Qiu|Huang, Qing-Wen|Huang, Jian-Kun|Yang, Xiao-Ning|Liu, Jing-Jing|Ren, Jian-Lin
PMID: 21769478
Journal: Mol Biol Rep. 2012 Apr;39(4):4229-36.
Title: The increased expression of DEC1 gene is related to HIF-1alpha protein in gastric cancer cell lines.
Author: Zheng, Yan|Shi, Xiaohong|Wang, Min|Jia, Yanfei|Li, Binbin|Zhang, Yi|Liu, Qinghua|Wang, Yunshan
PMID: 21779800
Journal: Endocrinology. 2012 Jul;153(7):3006-16.
Title: Induction of gastrin expression in gastrointestinal cells by hypoxia or cobalt is independent of hypoxia-inducible factor (HIF).
Author: Xiao, Lin|Kovac, Suzana|Chang, Mike|Shulkes, Arthur|Baldwin, Graham S|Patel, Oneel
PMID: 22593272
Journal: Int J Mol Sci. 2012;13(5):6521-33.
Title: Anti-proliferation and anti-invasion effects of diosgenin on gastric cancer BGC-823 cells with HIF-1alpha shRNAs.
Author: Mao, Zhu-Jun|Tang, Qian-Jue|Zhang, Ci-An|Qin, Zhi-Feng|Pang, Bin|Wei, Pin-Kang|Liu, Bo|Chou, Yuan-Neng
PMID: 22754381
Journal: Infect Agent Cancer. 2012 Aug 28;7(1):21.
Title: Epstein-barr virus infected gastric adenocarcinoma expresses latent and lytic viral transcripts and has a distinct human gene expression profile.
Author: Tang, Weihua|Morgan, Douglas R|Meyers, Michael O|Dominguez, Ricardo L|Martinez, Enrique|Kakudo, Kennichi|Kuan, Pei Fen|Banet, Natalie|Muallem, Hind|Woodward, Kimberly|Speck, Olga|Gulley, Margaret L
PMID: 22929309
Journal: Oncol Rep. 2012 Dec;28(6):2239-46.
Title: Hypoxia induces CXCR4 expression and biological activity in gastric cancer cells through activation of hypoxia-inducible factor-1alpha.
Author: Oh, Yoon Suk|Kim, Ha Yon|Song, Ik-Chan|Yun, Hwan-Jung|Jo, Deog-Yeon|Kim, Samyong|Lee, Hyo Jin
PMID: 23023480
Journal: Exp Ther Med. 2012 Sep;4(3):355-362.
Title: Knockdown of hypoxia-inducible factor-1alpha accelerates peritoneal dissemination via the upregulation of MMP-1 expression in gastric cancer cell lines.
Author: Hiraki, Masatsugu|Kitajima, Yoshihiko|Kai, Keita|Nakamura, Jun|Hashiguchi, Kazuyoshi|Noshiro, Hirokazu|Miyazaki, Kohji
PMID: 23181099
Journal: Int J Clin Oncol. 2013 Apr;18(2):293-304.
Title: Clinicopathological significance of hypoxia-inducible factor-1 alpha (HIF-1alpha) expression in gastric cancer.
Author: Isobe, Taro|Aoyagi, Keishiro|Koufuji, Kikuo|Shirouzu, Kazuo|Kawahara, Akihiko|Taira, Tomoki|Kage, Masayoshi
PMID: 22350022
Journal: Int J Oncol. 2013 Jan;42(1):44-54.
Title: Expression of pyruvate dehydrogenase kinase-1 in gastric cancer as a potential therapeutic target.
Author: Hur, Hoon|Xuan, Yi|Kim, Young Bae|Lee, Gwang|Shim, Wooyoung|Yun, Jisoo|Ham, In-Hye|Han, Sang-Uk
PMID: 23135628
Journal: Yonsei Med J. 2013 Mar 1;54(2):374-80.
Title: Blockade of VEGFR-1 and VEGFR-2 enhances paclitaxel sensitivity in gastric cancer cells.
Author: Hwang, Jun-Eul|Lee, Ji-Hee|Park, Mi-Ra|Kim, Dae-Eun|Bae, Woo-Kyun|Shim, Hyun-Jeong|Cho, Sang-Hee|Chung, Ik-Joo
PMID: 23364970
Journal: Diagn Pathol. 2013 Feb 27;8:37.
Title: Differentiated embryonic chondrocyte-expressed gene 1 is associated with hypoxia-inducible factor 1alpha and Ki67 in human gastric cancer.
Author: Jia, Yan-Fei|Xiao, Dong-Jie|Ma, Xiao-Li|Song, Yan-Yan|Hu, Rui|Kong, Yi|Zheng, Yan|Han, Shu-Yi|Hong, Ruan-Li|Wang, Yun-Shan
PMID: 23445622
Journal: Onkologie. 2013;36(3):102-7.
Title: Expression of Rac1, HIF-1alpha, and VEGF in gastric carcinoma: correlation with angiogenesis and prognosis.
Author: Zhan, Hongjie|Liang, Han|Liu, Xiangyu|Deng, Jingyu|Wang, Baogui|Hao, Xishan
PMID: 23485997
Journal: J Physiol Pharmacol. 2013 Feb;64(1):77-87.
Title: Molecular alterations in fibroblasts exposed to Helicobacter pylori: a missing link in bacterial inflammation progressing into gastric carcinogenesis?
Author: Krzysiek-Maczka, G|Targosz, A|Ptak-Belowska, A|Korbut, E|Szczyrk, U|Strzalka, M|Brzozowski, T
PMID: 23568974
Journal: World J Gastroenterol. 2013 Mar 28;19(12):1912-8.
Title: Expression and clinical significance of CD73 and hypoxia-inducible factor-1alpha in gastric carcinoma.
Author: Lu, Xiao-Xia|Chen, Yi-Tian|Feng, Bing|Mao, Xiao-Bei|Yu, Bo|Chu, Xiao-Yuan
PMID: 23569336
Journal: J Exp Clin Cancer Res. 2013 May 29;32:34.
Title: [18F]Fluorodeoxyglucose accumulation as a biological marker of hypoxic status but not glucose transport ability in gastric cancer.
Author: Takebayashi, Ryusuke|Izuishi, Kunihiko|Yamamoto, Yuka|Kameyama, Reiko|Mori, Hirohito|Masaki, Tsutomu|Suzuki, Yasuyuki
PMID: 23718763
Journal: Int J Med Sci. 2013 Jul 31;10(9):1217-23.
Title: Clinicopathological implications of the expression of hypoxia-related proteins in gastric cancer.
Author: Jung, Ji-Han|Im, Soyoung|Jung, Eun Sun|Kang, Chang Suk
PMID: 23935399
Journal: Int J Oncol. 2013 Nov;43(5):1431-40.
Title: HIF-1alpha is a crucial factor in the development of peritoneal dissemination via natural metastatic routes in scirrhous gastric cancer.
Author: Miyake, Shuusuke|Kitajima, Yoshihiko|Nakamura, Jun|Kai, Keita|Yanagihara, Kazuyoshi|Tanaka, Tomokazu|Hiraki, Masatsugu|Miyazaki, Kohji|Noshiro, Hirokazu
PMID: 23970191
Journal: Asian Pac J Cancer Prev. 2013;14(7):4195-8.
Title: Hypoxia-inducible factor 1 alpha (HIF-1alpha) as a prognostic indicator in patients with gastric tumors: a meta-analysis.
Author: Zhang, Zhi-Gang|Zhang, Qiu-Ning|Wang, Xiao-Hu|Tian, Jin-Hui
PMID: 23991975
Journal: Mol Biol Rep. 2013 Nov;40(11):6055-62.
Title: Prognostic value of HIF-1alpha expression in patients with gastric cancer.
Author: Zhu, Cheng-lin|Huang, Qiang|Liu, Chen-hai|Lin, Xian-sheng|Xie, Fang
PMID: 24057269
Journal: Cancers (Basel). 2013 Jan 10;5(1):15-26.
Title: The Critical Impact of HIF-1a on Gastric Cancer Biology.
Author: Kitajima, Yoshihiko|Miyazaki, Kohji
PMID: 24216696
Journal: PLoS One. 2013 Nov 29;8(11):e81709.
Title: RhoE promotes metastasis in gastric cancer through a mechanism dependent on enhanced expression of CXCR4.
Author: Feng, Bin|Li, Kai|Zhong, Haixing|Ren, Gui|Wang, Hefei|Shang, Yulong|Bai, Ming|Liang, Jie|Wang, Xin|Fan, Daiming
PMID: 24312338
Journal: Zhonghua Yi Xue Za Zhi. 2013 Nov 12;93(42):3375-8.
Title: [Expressions of Jumonji domain containing protein 2C and hypoxia-inducible factor-1alpha in gastric carcinoma and their clinical significance].
Author: Xu, Yuan|Yao, Hai-bo|Jin, Yi|Ma, Ying-yu|Wang, Hui-ju|Shao, Qin-shu
PMID: 24418035
Journal: Zhongguo Zhong Xi Yi Jie He Za Zhi. 2013 Nov;33(11):1515-9.
Title: [Effect of huazhuo jiedu hewei recipe on the mechanism of angiogenesis in precancerous lesions of gastric cancer rats].
Author: Gao, Shao-fang|Wang, Yan-gang|Li, Dian-gui|Pei, Lin
PMID: 24483113
Journal: Mol Carcinog. 2014 Sep;53(9):736-43.
Title: Prolyl hydroxylase 3 inhibited the tumorigenecity of gastric cancer cells.
Author: Cui, Lei|Qu, Jianguo|Dang, Shengchun|Mao, Zhengfa|Wang, Xuqing|Fan, Xin|Sun, Kang|Zhang, Jianxin
PMID: 23533015
Journal: Oncogene. 2014 Mar 13;33(11):1458-67.
Title: RUNX3 inhibits hypoxia-inducible factor-1alpha protein stability by interacting with prolyl hydroxylases in gastric cancer cells.
Author: Lee, S H|Bae, S C|Kim, K W|Lee, Y M
PMID: 23542169
Journal: Eur J Cancer. 2014 Jan;50(1):204-15.
Title: Caveolin-1 promotes gastric cancer progression by up-regulating epithelial to mesenchymal transition by crosstalk of signalling mechanisms under hypoxic condition.
Author: Kannan, Anbarasu|Krishnan, Arunkumar|Ali, Mohammed|Subramaniam, Shyama|Halagowder, Devaraj|Sivasithamparam, Niranjali Devaraj
PMID: 24070739
Journal: FEBS J. 2014 Jan;281(1):115-28.
Title: Up-regulation of survivin by AKT and hypoxia-inducible factor 1alpha contributes to cisplatin resistance in gastric cancer.
Author: Sun, Xue-Pu|Dong, Xuesong|Lin, Lele|Jiang, Xian|Wei, Zheng|Zhai, Bo|Sun, Bo|Zhang, Qiang|Wang, Xiaolong|Jiang, Hongchi|Krissansen, Geoffrey W|Qiao, Haiquan|Sun, Xueying
PMID: 24165223
Journal: Biochem Biophys Res Commun. 2014 Jan 3;443(1):156-60.
Title: Aberrant expression of SIRT3 is conversely correlated with the progression and prognosis of human gastric cancer.
Author: Yang, Bing|Fu, Xueqiong|Shao, Liang|Ding, Yu|Zeng, Duan
PMID: 24287180
Journal: Exp Cell Res. 2014 Feb 15;321(2):219-30.
Title: Dichloroacetate attenuates hypoxia-induced resistance to 5-fluorouracil in gastric cancer through the regulation of glucose metabolism.
Author: Xuan, Yi|Hur, Hoon|Ham, In-Hye|Yun, Jisoo|Lee, Ji-Yoon|Shim, Wooyoung|Kim, Young Bae|Lee, Gwang|Han, Sang-Uk|Cho, Yong Kwan
PMID: 24342832
Journal: World J Gastroenterol. 2014 Jan 28;20(4):1107-13.
Title: Meta-analysis of immunohistochemical expression of hypoxia inducible factor-1alpha as a prognostic role in gastric cancer.
Author: Lin, Shuang|Ma, Rui|Zheng, Xue-Yong|Yu, Hong|Liang, Xiao|Lin, Hui|Cai, Xiu-Jun
PMID: 24574785
Journal: Clin Cancer Res. 2014 May 1;20(9):2276-88.
Title: Interleukin-32 increases human gastric cancer cell invasion associated with tumor progression and metastasis.
Author: Tsai, Chung-Ying|Wang, Chia-Siu|Tsai, Ming-Ming|Chi, Hsiang-Cheng|Cheng, Wan-Li|Tseng, Yi-Hsin|Chen, Cheng-Yi|Lin, Crystal D|Wu, Jun-I|Wang, Lu-Hai|Lin, Kwang-Huei
PMID: 24602839
Journal: PLoS One. 2014 Mar 10;9(3):e90678.
Title: HIF-1 alpha overexpression correlates with poor overall survival and disease-free survival in gastric cancer patients post-gastrectomy.
Author: Chen, Li|Shi, Yan|Yuan, Jing|Han, Yalin|Qin, Rui|Wu, Qian|Jia, Baoqing|Wei, Bo|Wei, Lixin|Dai, Guanghai|Jiao, Shunchang
PMID: 24614305
Journal: PLoS One. 2014 Mar 19;9(3):e91842.
Title: Clinical and prognostic significance of HIF-1alpha, PTEN, CD44v6, and survivin for gastric cancer: a meta-analysis.
Author: Chen, Jing|Li, Tao|Liu, Qilun|Jiao, Haiyan|Yang, Wenjun|Liu, Xiaoxia|Huo, Zhenghao
PMID: 24647137
Journal: Tumour Biol. 2014 Jul;35(7):6801-8.
Title: Influence of different hypoxia models on metastatic potential of SGC-7901 gastric cancer cells.
Author: Miao, Zhi-Feng|Zhao, Ting-Ting|Wang, Zhen-Ning|Xu, Ying-Ying|Mao, Xiao-Yun|Wu, Jian-Hua|Liu, Xing-Yu|Xu, Hao|You, Yi|Xu, Hui-Mian
PMID: 24729089
Journal: World J Gastroenterol. 2014 Apr 21;20(15):4421-7.
Title: Expression of monocyte chemotactic protein-1/CCL2 in gastric cancer and its relationship with tumor hypoxia.
Author: Tao, Lei-Lei|Shi, Shu-Jing|Chen, Long-Bang|Huang, Gui-Chun
PMID: 24764682
Journal: Oncol Lett. 2014 May;7(5):1401-1408.
Title: Inhibition of phosphoinositide 3-kinase/Akt pathway decreases hypoxia inducible factor-1alpha expression and increases therapeutic efficacy of paclitaxel in human hypoxic gastric cancer cells.
Author: Zhang, Jing|Guo, Hua|Zhu, Jin-Shui|Yang, Yu-Chen|Chen, Wei-Xiong|Chen, Ni-Wei
PMID: 24765145
Journal: FASEB J. 2014 Sep;28(9):4055-67.
Title: Heat-shock protein 27 (HSP27, HSPB1) is up-regulated by MET kinase inhibitors and confers resistance to MET-targeted therapy.
Author: Musiani, Daniele|Konda, John David|Pavan, Simona|Torchiaro, Erica|Sassi, Francesco|Noghero, Alessio|Erriquez, Jessica|Perera, Timothy|Olivero, Martina|Di Renzo, Maria Flavia
PMID: 24903273
Journal: Nucleic Acids Res. 2014 Jul;42(12):8062-72.
Title: MicroRNA-382 induced by HIF-1alpha is an angiogenic miR targeting the tumor suppressor phosphatase and tensin homolog.
Author: Seok, Jin-Kyung|Lee, Sun Hee|Kim, Min Jung|Lee, You-Mie
PMID: 24914051
Journal: PLoS One. 2014 Jun 13;9(6):e99835.
Title: Altered expression of hypoxia-inducible factor-1alpha (HIF-1alpha) and its regulatory genes in gastric cancer tissues.
Author: Wang, Jihan|Ni, Zhaohui|Duan, Zipeng|Wang, Guoqing|Li, Fan
PMID: 24927122
Journal: Anticancer Res. 2014 Jul;34(7):3313-20.
Title: Validation of 2-mm tissue microarray technology in gastric cancer. Agreement of 2-mm TMAs and full sections for Glut-1 and Hif-1 alpha.
Author: Berlth, Felix|Monig, Stefan P|Schlosser, Hans A|Maus, Martin|Baltin, Christoph T H|Urbanski, Alexander|Drebber, Uta|Bollschweiler, Elfriede|Holscher, Arnulf H|Alakus, Hakan
PMID: 24982335
Journal: Cancer Sci. 2014 Sep;105(9):1109-15.
Title: Kruppel-like factor 8 contributes to hypoxia-induced MDR in gastric cancer cells.
Author: Zhang, Hui|Sun, Li|Xiao, Xiao|Xie, Rougang|Liu, Changhao|Wang, Yafang|Wei, Yanling|Zhang, Hongbo|Liu, Lili
PMID: 25040744
Journal: Stem Cells. 2014 Dec;32(12):3062-74.
Title: Peritoneal milky spots serve as a hypoxic niche and favor gastric cancer stem/progenitor cell peritoneal dissemination through hypoxia-inducible factor 1alpha.
Author: Miao, Zhi-Feng|Wang, Zhen-Ning|Zhao, Ting-Ting|Xu, Ying-Ying|Gao, Jian|Miao, Feng|Xu, Hui-Mian
PMID: 25142304
Journal: World J Gastroenterol. 2014 Oct 14;20(38):13705-17.
Title: Mechanisms of regulation of PFKFB expression in pancreatic and gastric cancer cells.
Author: Minchenko, Oleksandr H|Tsuchihara, Katsuya|Minchenko, Dmytro O|Bikfalvi, Andreas|Esumi, Hiroyasu
PMID: 25320508
Journal: Gastric Cancer. 2015 Apr;18(2):262-70.
Title: Comparison of site-specific gene expression levels in primary tumors and synchronous lymph node metastases in advanced gastric cancer.
Author: Naruke, Akira|Azuma, Mizutomo|Takeuchi, Atsuko|Ishido, Kenji|Katada, Chikatoshi|Sasaki, Tohru|Higuchi, Katsuhiko|Tanabe, Satoshi|Saegusa, Makoto|Koizumi, Wasaburo
PMID: 24651981
Journal: Oncogene. 2015 Jul;34(29):3826-38.
Title: The formyl peptide receptor 1 exerts a tumor suppressor function in human gastric cancer by inhibiting angiogenesis.
Author: Prevete, N|Liotti, F|Visciano, C|Marone, G|Melillo, R M|de Paulis, A
PMID: 25263443
Journal: Oncol Rep. 2015 Jan;33(1):457-63.
Title: Baicalein reverses hypoxia-induced 5-FU resistance in gastric cancer AGS cells through suppression of glycolysis and the PTEN/Akt/HIF-1alpha signaling pathway.
Author: Chen, Fenglin|Zhuang, Mingkai|Zhong, Canmei|Peng, Jun|Wang, Xiaozhong|Li, Jianying|Chen, Zhixin|Huang, Yuehong
PMID: 25333894
Journal: Cell Signal. 2015 Mar;27(3):663-72.
Title: Interplay between the prostaglandin transporter OATP2A1 and prostaglandin E2-mediated cellular effects.
Author: Bujok, Krystyna|Glaeser, Hartmut|Schuh, Wolfgang|Rau, Tilman T|Schmidt, Ingrid|Fromm, Martin F|Mandery, Kathrin
PMID: 25433165
Journal: Med Hypotheses. 2015 Mar;84(3):209-12.
Title: MIR210 as a potential molecular target to block invasion and metastasis of gastric cancer.
Author: Yu, Pengfei|Fan, Sunfu|Huang, Ling|Yang, Litao|Du, Yian
PMID: 25618442
Journal: Am J Cancer Res. 2014 Dec 15;5(1):321-32. eCollection 2015.
Title: Overexpression of CDX2 in gastric cancer cells promotes the development of multidrug resistance.
Author: Yan, Lin-Hai|Wei, Wei-Yuan|Cao, Wen-Long|Zhang, Xiao-Shi|Xie, Yu-Bo|Xiao, Qiang
PMID: 25628941
Journal: Dig Dis Sci. 2015 Jun;60(6):1655-62.
Title: Antisense Long Noncoding RNA HIF1A-AS2 Is Upregulated in Gastric Cancer and Associated with Poor Prognosis.
Author: Chen, Wen-Ming|Huang, Ming-de|Kong, Rong|Xu, Tong-Peng|Zhang, Er-Bao|Xia, Rui|Sun, Ming|De, Wei|Shu, Yong-Qian
PMID: 25686741
Journal: J Immunol. 2015 Apr 1;194(7):3259-66.
Title: Myeloid HIF-1 is protective in Helicobacter pylori-mediated gastritis.
Author: Matak, Pavle|Heinis, Mylene|Mathieu, Jacques R R|Corriden, Ross|Cuvellier, Sylvain|Delga, Stephanie|Mounier, Remi|Rouquette, Alexandre|Raymond, Josette|Lamarque, Dominique|Emile, Jean-Francois|Nizet, Victor|Touati, Eliette|Peyssonnaux, Carole
PMID: 25710915
Journal: Cell Signal. 2015 Jul;27(7):1369-79.
Title: CREB is a key negative regulator of carbonic anhydrase IX (CA9) in gastric cancer.
Author: Wang, Guanqiao|Cheng, Zhenguo|Liu, Funan|Zhang, Hongyan|Li, Jiabin|Li, Feng
PMID: 25843777
Journal: Mol Biol (Mosk). 2015 Jan-Feb;49(1):129-37.
Title: [Under hypoxia condition contactin-1 regulates migration of MKN45 cells through RhoA pathway].
Author: Yang, G|Song, J G|Li, Y|Gong, S P
PMID: 25916117
Journal: Biochem Biophys Res Commun. 2015 Jul 3;462(3):227-32.
Title: Overexpression of long non-coding RNA PVT1 in gastric cancer cells promotes the development of multidrug resistance.
Author: Zhang, Xian-wen|Bu, Ping|Liu, Liang|Zhang, Xi-zhi|Li, Jun
PMID: 25956062
Journal: Am J Cancer Res. 2015 Mar 15;5(4):1423-34. eCollection 2015.
Title: Metformin inhibits gastric cancer via the inhibition of HIF1alpha/PKM2 signaling.
Author: Chen, Guangxia|Feng, Wan|Zhang, Shu|Bian, Kangqi|Yang, Yan|Fang, Cheng|Chen, Min|Yang, Jun|Zou, Xiaoping
PMID: 26101707
Journal: Cancer Biol Ther. 2015;16(8):1140-7.
Title: The potential predictive role of nuclear NHERF1 expression in advanced gastric cancer patients treated with epirubicin/oxaliplatin/capecitabine first line chemotherapy.
Author: Mangia, Anita|Caldarola, Lucia|Dell'Endice, Stefania|Scarpi, Emanuela|Saragoni, Luca|Monti, Manlio|Santini, Daniele|Brunetti, Oronzo|Simone, Giovanni|Silvestris, Nicola
PMID: 26126066
Journal: PLoS One. 2015 Jul 6;10(7):e0130839.
Title: Implication of Leptin-Signaling Proteins and Epstein-Barr Virus in Gastric Carcinomas.
Author: Choi, Euno|Byeon, Sun-ju|Kim, Soo Hee|Lee, Hyun Ju|Kwon, Hyeong Ju|Ahn, HyeSeong|Kim, Dong Ha|Chang, Mee Soo
PMID: 26147886
Journal: PLoS One. 2015 Aug 20;10(8):e0132746.
Title: HIF-1alpha Induces Multidrug Resistance in Gastric Cancer Cells by Inducing MiR-27a.
Author: Zhao, Qun|Li, Yong|Tan, Bi-Bo|Fan, Li-Qiao|Yang, Pei-Gang|Tian, Yuan
PMID: 26292288
Journal: Mol Biol (Mosk). 2015 Jul-Aug;49(4):658-66.
Title: [Changes in the number of copies of genetic loci in gastric cancer].
Author: Kit, O I|Vodolazhsky, D I|Kutilin, D S|Gudueva, E N
PMID: 26299866
Journal: Oncol Rep. 2015 Nov;34(5):2385-94.
Title: Expression of RAP1B is associated with poor prognosis and promotes an aggressive phenotype in gastric cancer.
Author: Yang, Ya|Li, Min|Yan, Yan|Zhang, Jia|Sun, Kai|Qu, Jing-Kun|Wang, Jian-Sheng|Duan, Xiao-Yi
PMID: 26329876
Journal: Oncol Rep. 2015 Nov;34(5):2541-6.
Title: Involvement of nuclear receptor RZR/RORgamma in melatonin-induced HIF-1alpha inactivation in SGC-7901 human gastric cancer cells.
Author: Wang, Ri-Xiong|Liu, Hui|Xu, Li|Zhang, Hui|Zhou, Rui-Xiang
PMID: 26330273
Journal: PLoS One. 2015 Sep 4;10(9):e0137257.
Title: The Apoptotic Effect of HIF-1alpha Inhibition Combined with Glucose plus Insulin Treatment on Gastric Cancer under Hypoxic Conditions.
Author: Tanaka, Tomokazu|Kitajima, Yoshihiko|Miyake, Shuusuke|Yanagihara, Kazuyoshi|Hara, Hiromitsu|Nishijima-Matsunobu, Aki|Baba, Koichi|Shida, Masaaki|Wakiyama, Kota|Nakamura, Jun|Noshiro, Hirokazu
PMID: 26339797
Journal: Carcinogenesis. 2015 Dec;36(12):1511-20.
Title: Diffuse-type gastric cancer cells switch their driver pathways from FGFR2 signaling to SDF1/CXCR4 axis in hypoxic tumor microenvironments.
Author: Kinoshita, Haruhito|Yashiro, Masakazu|Fukuoka, Tatsunari|Hasegawa, Tsuyoshi|Morisaki, Tamami|Kasashima, Hiroaki|Masuda, Go|Noda, Satoru|Hirakawa, Kosei
PMID: 26385890
Journal: Cancer Biomark. 2015;15(6):851-60.
Title: Increased levels of serum and tissue miR-107 in human gastric cancer: Correlation with tumor hypoxia.
Author: Ayremlou, Nooshin|Mozdarani, Hossein|Mowla, Seyed Javad|Delavari, Alireza
PMID: 26406411
Journal: Oncotarget. 2015 Nov 24;6(37):39839-54.
Title: Inhibition of autophagy promotes metastasis and glycolysis by inducing ROS in gastric cancer cells.
Author: Qin, Wenjie|Li, Chao|Zheng, Wen|Guo, Qingqu|Zhang, Yuefeng|Kang, Muxing|Zhang, Bo|Yang, Bin|Li, Baozhong|Yang, Haijun|Wu, Yulian
PMID: 26497999
Journal: Int J Oncol. 2015 Dec;47(6):2226-32.
Title: Sulforaphane inhibits hypoxia-induced HIF-1alpha and VEGF expression and migration of human colon cancer cells.
Author: Kim, Dong Hwan|Sung, Bokyung|Kang, Yong Jung|Hwang, Seong Yeon|Kim, Min Jeong|Yoon, Jeong-Hyun|Im, Eunok|Kim, Nam Deuk
PMID: 26498863
Journal: Sci Rep. 2015 Nov 16;5:16382.
Title: Targeting inhibition of extracellular signal-regulated kinase kinase pathway with AZD6244 (ARRY-142886) suppresses growth and angiogenesis of gastric cancer.
Author: Gao, Jin-Hang|Wang, Chun-Hui|Tong, Huan|Wen, Shi-Lei|Huang, Zhi-Yin|Tang, Cheng-Wei
PMID: 26567773
Journal: Exp Ther Med. 2015 Aug;10(2):717-722.
Title: microRNA-18a regulates gastric carcinoma cell apoptosis and invasion by suppressing hypoxia-inducible factor-1alpha expression.
Author: Wu, Fubing|Huang, Wen|Wang, Xing
PMID: 26622381
Journal: Tumour Biol. 2016 Mar;37(3):3043-9.
Title: Repression of PES1 expression inhibits growth of gastric cancer.
Author: Li, Jieping|Zhou, Xiaodong|Lan, Xiaopeng|Zeng, Guobin|Jiang, Xuping|Huang, Zongming
PMID: 26423399
Journal: Int J Cancer. 2016 Apr 1;138(7):1680-8.
Title: Rab11-FIP2 promotes the metastasis of gastric cancer cells.
Author: Dong, Wenjie|Qin, Guohui|Shen, Ruizhe
PMID: 26502090
Journal: J Mol Med (Berl). 2016 Apr;94(4):401-15.
Title: PRL-3 promotes gastric cancer migration and invasion through a NF-kappaB-HIF-1alpha-miR-210 axis.
Author: Zhang, Cheng|Tian, Wei|Meng, Lin|Qu, Like|Shou, Chengchao
PMID: 26548949
Journal: Oncotarget. 2016 Feb 9;7(6):6693-710.
Title: Annexin A1 sustains tumor metabolism and cellular proliferation upon stable loss of HIF1A.
Author: Rohwer, Nadine|Bindel, Fabian|Grimm, Christina|Lin, Suling J|Wappler, Jessica|Klinger, Bertram|Bluthgen, Nils|Du Bois, Ilona|Schmeck, Bernd|Lehrach, Hans|de Graauw, Marjo|Goncalves, Emanuel|Saez-Rodriguez, Julio|Tan, Patrick|Grabsch, Heike I|Prigione, Ale
PMID: 26760764
Journal: Cancer Biol Ther. 2016 Apr 2;17(4):400-6.
Title: Role of miR-27a, miR-181a and miR-20b in gastric cancer hypoxia-induced chemoresistance.
Author: Danza, Katia|Silvestris, Nicola|Simone, Giovanni|Signorile, Michele|Saragoni, Luca|Brunetti, Oronzo|Monti, Manlio|Mazzotta, Annalisa|De Summa, Simona|Mangia, Anita|Tommasi, Stefania
PMID: 26793992
Journal: Int J Oncol. 2016 Apr;48(4):1379-90.
Title: Impaired mitophagy activates mtROS/HIF-1alpha interplay and increases cancer aggressiveness in gastric cancer cells under hypoxia.
Author: Shida, Masaaki|Kitajima, Yoshihiko|Nakamura, Jun|Yanagihara, Kazuyoshi|Baba, Koichi|Wakiyama, Kota|Noshiro, Hirokazu
PMID: 26820502
Journal: Biochem Biophys Res Commun. 2016 Feb 26;471(1):205-12.
Title: Cobalt chloride-mediated protein kinase Calpha (PKCalpha) phosphorylation induces hypoxia-inducible factor 1alpha (HIF1alpha) in the nucleus of gastric cancer cell.
Author: Rath, Suvasmita|Anand, Aditya|Ghosh, Nilabh|Das, Lopamudra|Kokate, Shrikant B|Dixit, Pragyesh|Majhi, Swetapadma|Rout, Niranjan|Singh, Shivaram P|Bhattacharyya, Asima
PMID: 26826385
Journal: Oncol Lett. 2016 Feb;11(2):1026-1034.
Title: Regulation and clinical significance of the hypoxia-induced expression of ANGPTL4 in gastric cancer.
Author: Kubo, Hiroshi|Kitajima, Yoshihiko|Kai, Keita|Nakamura, Jun|Miyake, Shuusuke|Yanagihara, Kazuyoshi|Morito, Kiyoto|Tanaka, Tomokazu|Shida, Masaaki|Noshiro, Hirokazu
PMID: 26893686
Journal: Oncol Res. 2016;23(3):129-36.
Title: Enhancement of Drug Sensitivity by Knockdown of HIF-1alpha in Gastric Carcinoma Cells.
Author: Zhao, Qun|Tan, Bi-Bo|Li, Yong|Fan, Li-Qiao|Yang, Pei-Gang|Tian, Yuan
PMID: 26931435
Journal: Oncol Rep. 2016 May;35(5):2624-34.
Title: Inhibition of peritoneal metastasis of human gastric cancer cells by dextran sulphate through the reduction in HIF-1alpha and ITGbeta1 expression.
Author: Xu, Yuanyi|Jin, Xiu|Huang, Yunning|Dong, Jianda|Wang, Honghong|Wang, Xiaofei|Cao, Xiangmei
PMID: 27004522
Journal: Oncotarget. 2016 Apr 26;7(17):24466-82.
Title: MicroRNA-421 regulated by HIF-1alpha promotes metastasis, inhibits apoptosis, and induces cisplatin resistance by targeting E-cadherin and caspase-3 in gastric cancer.
Author: Ge, Xiaoxiao|Liu, Xinyang|Lin, Fengjuan|Li, Peng|Liu, Kaiyi|Geng, Ruixuan|Dai, Congqi|Lin, Ying|Tang, Wenbo|Wu, Zheng|Chang, Jinjia|Lu, Jianwei|Li, Jin
PMID: 27016414
Journal: Cancer Lett. 2016 Jun 28;376(1):155-64.
Title: Tetracycline-inducible shRNA targeting antisense long non-coding RNA HIF1A-AS2 represses the malignant phenotypes of bladder cancer.
Author: Chen, Mingwei|Zhuang, Chengle|Liu, Yuchen|Li, Jianfa|Dai, Fen|Xia, Ming|Zhan, Yonghao|Lin, Junhao|Chen, Zhicong|He, Anbang|Xu, Wen|Zhao, Guoping|Guo, Yinglu|Cai, Zhiming|Huang, Weiren
PMID: 27018306
Journal: Oncogenesis. 2016 May 9;5:e224.
Title: MiR-186 inhibited aerobic glycolysis in gastric cancer via HIF-1alpha regulation.
Author: Liu, L|Wang, Y|Bai, R|Yang, K|Tian, Z
PMID: 27159677
Journal: Zhonghua Yi Xue Za Zhi. 2016 May 17;96(18):1418-23.
Title: [Expression of hypoxia-inducible factor 1alpha in gastric cancer and its clinical signficance].
Author: Wu, Y L|Hu, L N|Zheng, C D|Sun, R C|Zhang, S X|Yan, Q|Li, Y X
PMID: 27266349
Journal: APMIS. 2016 Sep;124(9):748-56.
Title: Hypoxic inactivation of glycogen synthase kinase-3beta promotes gastric tumor growth and angiogenesis by facilitating hypoxia-inducible factor-1 signaling.
Author: Ko, Young San|Cho, Sung Jin|Park, Jinju|Choi, Yiseul|Lee, Jae-Seon|Youn, Hong-Duk|Kim, Woo Ho|Kim, Min A|Park, Jong-Wan|Lee, Byung Lan
PMID: 27365055
Journal: Oncol Lett. 2016 Aug;12(2):897-903.
Title: Melatonin downregulates nuclear receptor RZR/RORgamma expression causing growth-inhibitory and anti-angiogenesis activity in human gastric cancer cells in vitro and in vivo.
Author: Wang, Ri-Xiong|Liu, Hui|Xu, Li|Zhang, Hui|Zhou, Rui-Xiang
PMID: 27446366
Journal: Mol Oncol. 2016 Nov;10(9):1473-1484.
Title: Biglycan stimulates VEGF expression in endothelial cells by activating the TLR signaling pathway.
Author: Hu, Lei|Zang, Ming-de|Wang, He-Xiao|Li, Jian-Fang|Su, Li-Ping|Yan, Min|Li, Chen|Yang, Qiu-Meng|Liu, Bing-Ya|Zhu, Zheng-Gang
PMID: 27590684
Journal: Oncotarget. 2017 Jan 3;8(1):1262-1277.
Title: Down regulation of RNA binding motif, single-stranded interacting protein 3, along with up regulation of nuclear HIF1A correlates with poor prognosis in patients with gastric cancer.
Author: Wu, Youliang|Yun, Dapeng|Zhao, Yingjie|Wang, Yuqi|Sun, Ruochuan|Yan, Qiang|Zhang, Shangxin|Lu, Mingdian|Zhang, Zhen|Lu, Daru|Li, Yongxiang
PMID: 27902480
Journal: Oncotarget. 2017 Feb 21;8(8):13174-13185.
Title: Oncometabolite succinate promotes angiogenesis by upregulating VEGF expression through GPR91-mediated STAT3 and ERK activation.
Author: Mu, Xianmin|Zhao, Ting|Xu, Che|Shi, Wei|Geng, Biao|Shen, Jiajia|Zhang, Chen|Pan, Jinshun|Yang, Jing|Hu, Shi|Lv, Yuanfang|Wen, Hao|You, Qiang
PMID: 28061458
Journal: Acta Biochim Biophys Sin (Shanghai). 2017 Feb 6;49(2):119-127.
Title: Expression of HMGB2 indicates worse survival of patients and is required for the maintenance of Warburg effect in pancreatic cancer.
Author: Cai, Xin|Ding, Hongjian|Liu, Yanxia|Pan, Gaofeng|Li, Qingguo|Yang, Zhen|Liu, Weiyan
PMID: 28069585
Journal: Oncotarget. 2017 Feb 7;8(6):9535-9545.
Title: HIF-1alpha induces the epithelial-mesenchymal transition in gastric cancer stem cells through the Snail pathway.
Author: Yang, Shi-Wei|Zhang, Zhi-Gang|Hao, Ying-Xue|Zhao, Yong-Liang|Qian, Feng|Shi, Yan|Li, Ping-Ang|Liu, Chun-Yang|Yu, Pei-Wu
PMID: 28076840
Journal: Biomed Pharmacother. 2017 Apr;88:302-308.
Title: The long noncoding RNA PVT1 functions as a competing endogenous RNA by sponging miR-186 in gastric cancer.
Author: Huang, Tao|Liu, Hong Wei|Chen, Jia Qi|Wang, Shou Han|Hao, Li Qun|Liu, Miao|Wang, Bin
PMID: 28122299
Journal: Mol Cancer. 2017 Feb 7;16(1):35.
Title: Hypoxia-inducible microRNA-224 promotes the cell growth, migration and invasion by directly targeting RASSF8 in gastric cancer.
Author: He, Chuan|Wang, Libo|Zhang, Jiantao|Xu, Hong
PMID: 28173803
Journal: Genes Chromosomes Cancer. 2017 Jul;56(7):535-547.
Title: Integrated expression analysis identifies transcription networks in mouse and human gastric neoplasia.
Author: Chen, Zheng|Soutto, Mohammed|Rahman, Bushra|Fazili, Muhammad W|Peng, DunFa|Blanca Piazuelo, Maria|Chen, Heidi|Kay Washington, M|Shyr, Yu|El-Rifai, Wael
PMID: 28281307
Journal: Oncol Lett. 2017 Feb;13(2):967-972.
Title: Hypoxia regulates CD44 expression via hypoxia-inducible factor-1alpha in human gastric cancer cells.
Author: Liang, Gai|Li, Shuang|Du, Wei|Ke, Qinghua|Cai, Jun|Yang, Jiyuan
PMID: 28356986
Journal: Front Cell Infect Microbiol. 2017 Mar 28;7:92.
Title: Helicobacter pylori Induced Phosphatidylinositol-3-OH Kinase/mTOR Activation Increases Hypoxia Inducible Factor-1alpha to Promote Loss of Cyclin D1 and G0/G1 Cell Cycle Arrest in Human Gastric Cells.
Author: Canales, Jimena|Valenzuela, Manuel|Bravo, Jimena|Cerda-Opazo, Paulina|Jorquera, Carla|Toledo, Hector|Bravo, Denisse|Quest, Andrew F G
PMID: 28401064
Journal: Oncogenesis. 2017 Apr 17;6(4):e318.
Title: MiR-186 inhibited aerobic glycolysis in gastric cancer via HIF-1alpha regulation.
Author: Liu, L|Wang, Y|Bai, R|Yang, K|Tian, Z
PMID: 28414319
Journal: Oncol Lett. 2017 Apr;13(4):2703-2707.
Title: Chemotherapy regimen based on sorafenib combined with 5-FU on HIF-1alpha and VEGF expression and survival in advanced gastric cancer patients.
Author: Cheng, Ronghui|Yong, Hongmei|Xia, Yunhong|Xie, Qingsong|Gao, Guangyi|Zhou, Xueyi
PMID: 28454454
Journal: PLoS One. 2017 Jun 8;12(6):e0179202.
Title: Gastrointestinal cancer cells treatment with bevacizumab activates a VEGF autoregulatory mechanism involving telomerase catalytic subunit hTERT via PI3K-AKT, HIF-1alpha and VEGF receptors.
Author: Mahfouz, Nadine|Tahtouh, Roula|Alaaeddine, Nada|El Hajj, Joelle|Sarkis, Riad|Hachem, Ray|Raad, Issam|Hilal, George
PMID: 28594907
Journal: J Dig Dis. 2017 Sep;18(9):511-520.
Title: Hypoxia/IL-1alpha axis promotes gastric cancer progression and drug resistance.
Author: Xuan, Yi|Wang, Ya Nong
PMID: 28608600
Journal: PLoS Pathog. 2017 Jun 15;13(6):e1006404.
Title: Hypoxia-inducible factor-1alpha plays roles in Epstein-Barr virus's natural life cycle and tumorigenesis by inducing lytic infection through direct binding to the immediate-early BZLF1 gene promoter.
Author: Kraus, Richard J|Yu, Xianming|Cordes, Blue-Leaf A|Sathiamoorthi, Saraniya|Iempridee, Tawin|Nawandar, Dhananjay M|Ma, Shidong|Romero-Masters, James C|McChesney, Kyle G|Lin, Zhen|Makielski, Kathleen R|Lee, Denis L|Lambert, Paul F|Johannsen, Eric C|Kenney, S
PMID: 28617871
Journal: Food Funct. 2017 Sep 20;8(9):3319-3326.
Title: Anti-tumor bioactivities of curcumin on mice loaded with gastric carcinoma.
Author: Wang, Xiao-Ping|Wang, Qiao-Xia|Lin, Huan-Ping|Chang, Na
PMID: 28848967
Journal: Sci Rep. 2017 Sep 11;7(1):11127.
Title: Hypoxia-induced ANGPTL4 sustains tumour growth and anoikis resistance through different mechanisms in scirrhous gastric cancer cell lines.
Author: Baba, Koichi|Kitajima, Yoshihiko|Miyake, Shuusuke|Nakamura, Jun|Wakiyama, Kota|Sato, Hirofumi|Okuyama, Keiichiro|Kitagawa, Hiroshi|Tanaka, Tomokazu|Hiraki, Masatsugu|Yanagihara, Kazuyoshi|Noshiro, Hirokazu
PMID: 28894280
Journal: Mol Med Rep. 2017 Nov;16(5):6882-6889.
Title: PHD3 affects gastric cancer progression by negatively regulating HIF1A.
Author: Xia, Ying-Jie|Jiang, Xiao-Ting|Jiang, Shi-Bin|He, Xu-Jun|Luo, Jun-Gang|Liu, Zheng-Chuang|Wang, Liang|Tao, Hou-Quan|Chen, Jian-Zhong
PMID: 28901473
Journal: Am J Cancer Res. 2017 Sep 1;7(9):1913-1925. eCollection 2017.
Title: Tumor microenvironment interruption: a novel anti-cancer mechanism of Proton-pump inhibitor in gastric cancer by suppressing the release of microRNA-carrying exosomes.
Author: Guan, Xu-Wen|Zhao, Fang|Wang, Jing-Ya|Wang, Hai-Yan|Ge, Shao-Hua|Wang, Xia|Zhang, Le|Liu, Rui|Ba, Yi|Li, Hong-Li|Deng, Ting|Zhou, Li-Kun|Bai, Ming|Ning, Tao|Zhang, Hai-Yang|Huang, Ding-Zhi
PMID: 28979813
Journal: Cell Death Dis. 2017 Oct 26;8(10):e3144.
Title: Plasminogen kringle 5 suppresses gastric cancer via regulating HIF-1alpha and GRP78.
Author: Fang, Shuhuan|Hong, Honghai|Li, Lei|He, Dan|Xu, Zumin|Zuo, Shaoyuan|Han, Jing|Wu, Qiyuan|Dai, Zhiyu|Cai, Weibin|Ma, Jianxing|Shao, Chunkui|Gao, Guoquan|Yang, Xia
PMID: 29072683
Journal: Oncotarget. 2017 Jun 27;8(45):78365-78378.
Title: Regulation of SIRT3 signal related metabolic reprogramming in gastric cancer by Helicobacter pylori oncoprotein CagA.
Author: Lee, Do Yeon|Jung, Dawoon E|Yu, Sung Sook|Lee, Yeo Song|Choi, Beom Ku|Lee, Yong Chan
PMID: 29108235
Journal: Oncogene. 2018 Sep;37(39):5355-5366.
Title: SYT7 acts as a driver of hepatic metastasis formation of gastric cancer cells.
Author: Kanda, Mitsuro|Tanaka, Haruyoshi|Shimizu, Dai|Miwa, Takashi|Umeda, Shinichi|Tanaka, Chie|Kobayashi, Daisuke|Hattori, Norifumi|Suenaga, Masaya|Hayashi, Masamichi|Iwata, Naoki|Yamada, Suguru|Fujiwara, Michitaka|Kodera, Yasuhiro
PMID: 28915664
Journal: Oncogene. 2018 Feb 8;37(6):744-755.
Title: Extracellular matrix protein 1 promotes cell metastasis and glucose metabolism by inducing integrin beta4/FAK/SOX2/HIF-1alpha signaling pathway in gastric cancer.
Author: Gan, L|Meng, J|Xu, M|Liu, M|Qi, Y|Tan, C|Wang, Y|Zhang, P|Weng, W|Sheng, W|Huang, M|Wang, Z
PMID: 29059156
Journal: Oncogene. 2018 Sep;37(39):5355-5366.
Title: SYT7 acts as a driver of hepatic metastasis formation of gastric cancer cells.
Author: Kanda, Mitsuro|Tanaka, Haruyoshi|Shimizu, Dai|Miwa, Takashi|Umeda, Shinichi|Tanaka, Chie|Kobayashi, Daisuke|Hattori, Norifumi|Suenaga, Masaya|Hayashi, Masamichi|Iwata, Naoki|Yamada, Suguru|Fujiwara, Michitaka|Kodera, Yasuhiro
PMID: 29328491
Journal: Cancer Sci. 2018 Apr;109(4):988-1000.
Title: Long noncoding RNA BC005927 upregulates EPHB4 and promotes gastric cancer metastasis under hypoxia.
Author: Liu, Xiangqiang|Wang, Yafang|Sun, Li|Min, Jie|Liu, Jiaming|Chen, Di|Zhang, Hongbo|Zhang, Hongwei|Zhang, Helong|Zhou, Yongan|Liu, Lili
PMID: 29383777
Journal: Eur J Pharmacol. 2018 Jun 5;828:67-79.
Title: A novel HDAC6 inhibitor exerts an anti-cancer effect by triggering cell cycle arrest and apoptosis in gastric cancer.
Author: Dong, Jing|Zheng, Nan|Wang, Xue|Tang, Chu|Yan, Ping|Zhou, Hai-Bing|Huang, Jian
PMID: 29563065
Journal: Phytother Res. 2018 Jul;32(7):1364-1372.
Title: Astragaloside IV reverses MNNG-induced precancerous lesions of gastric carcinoma in rats: Regulation on glycolysis through miRNA-34a/LDHA pathway.
Author: Zhang, Chengzhe|Cai, Tiantian|Zeng, Xiaohui|Cai, Dake|Chen, Yuxing|Huang, Xuejun|Gan, Haining|Zhuo, Juncheng|Zhao, Ziming|Pan, Huafeng|Li, Siyi
PMID: 29577459
Journal: FASEB J. 2018 Oct;32(10):5378-5389.
Title: Acetylation-mediated Siah2 stabilization enhances PHD3 degradation in Helicobacter pylori-infected gastric epithelial cancer cells.
Author: Kokate, Shrikant Babanrao|Dixit, Pragyesh|Das, Lopamudra|Rath, Suvasmita|Roy, Arjama Dhar|Poirah, Indrajit|Chakraborty, Debashish|Rout, Niranjan|Singh, Shivaram Prasad|Bhattacharyya, Asima
PMID: 29688807
Journal: Am J Chin Med. 2018;46(4):875-890.
Title: Pachymic Acid Sensitizes Gastric Cancer Cells to Radiation Therapy by Upregulating Bax through Hypoxia.
Author: Lu, Chunwei|Cai, Dingfang|Ma, Jun
PMID: 29737213
Journal: Cell Death Dis. 2018 May 21;9(6):579.
Title: Novel peptide GX1 inhibits angiogenesis by specifically binding to transglutaminase-2 in the tumorous endothelial cells of gastric cancer.
Author: Lei, Zhijie|Chai, Na|Tian, Miaomiao|Zhang, Ying|Wang, Guodong|Liu, Jian|Tian, Zuhong|Yi, Xiaofang|Chen, Di|Li, Xiaowei|Yu, Pengfei|Hu, Hao|Xu, Bing|Jian, Chao|Bian, Zhenyuan|Guo, Hao|Wang, Jinpeng|Peng, Shiming|Nie, Yongzhan|Huang, Niu|Hu, Sijun|Wu, Kaich
PMID: 29785022
Journal: Oncogene. 2018 Sep;37(39):5355-5366.
Title: SYT7 acts as a driver of hepatic metastasis formation of gastric cancer cells.
Author: Kanda, Mitsuro|Tanaka, Haruyoshi|Shimizu, Dai|Miwa, Takashi|Umeda, Shinichi|Tanaka, Chie|Kobayashi, Daisuke|Hattori, Norifumi|Suenaga, Masaya|Hayashi, Masamichi|Iwata, Naoki|Yamada, Suguru|Fujiwara, Michitaka|Kodera, Yasuhiro
PMID: 29858600
Journal: Biosci Rep. 2018 Jun 13. pii: BSR20180741.
Title: Downregulation of HIF-1alpha inhibits the proliferation, migration and invasion of gastric cancer by inhibiting PI3K/AKT pathway and VEGF expression.
Author: Zhang, Jingjing|Xu, Jun|Dong, Yonghong|Huang, Bo
PMID: 29899167
Journal: World J Gastroenterol. 2018 Jun 14;24(22):2381-2391.
Title: Prognostic value of hypoxia-inducible factor-1 alpha and prolyl 4-hydroxylase beta polypeptide overexpression in gastric cancer.
Author: Zhang, Jun|Wu, Yue|Lin, Yu-Hang|Guo, Shuai|Ning, Pei-Fang|Zheng, Zhi-Chao|Wang, Yue|Zhao, Yan
PMID: 29904245
Journal: J Cell Mol Med. 2018 Sep;22(9):4377-4386.
Title: Aldolase A as a prognostic factor and mediator of progression via inducing epithelial-mesenchymal transition in gastric cancer.
Author: Jiang, Zhonghua|Wang, Xiaohong|Li, Jing|Yang, Hongmei|Lin, Xin
PMID: 29992789
Journal: Cancer Manag Res. 2018 Jul 4;10:1865-1874.
Title: The effect of HIF-1alpha and PKM1 expression on acquisition of chemoresistance.
Author: Okazaki, Mitsuyoshi|Fushida, Sachio|Tsukada, Tomoya|Kinoshita, Jun|Oyama, Katsunobu|Miyashita, Tomoharu|Ninomiya, Itasu|Harada, Shinichi|Ohta, Tetsuo
PMID: 30013393
Journal: Am J Transl Res. 2018 Jul 15;10(7):2055-2067. eCollection 2018.
Title: The molecular mechanism and clinical significance of LDHA in HER2-mediated progression of gastric cancer.
Author: Zhu, Weiyou|Ma, Ling|Qian, Jing|Xu, Jin|Xu, Tongpeng|Pang, Lijun|Zhou, Hong|Shu, Yongqian|Zhou, Jianwei
PMID: 30093943
Journal: BMC Complement Altern Med. 2018 Sep 10;18(1):250.
Title: Weipixiao attenuate early angiogenesis in rats with gastric precancerous lesions.
Author: Zeng, Jinhao|Yan, Ran|Pan, Huafeng|You, Fengming|Cai, Tiantian|Liu, Wei|Zheng, Chuan|Zhao, Ziming|Gong, Daoyin|Chen, Longhui|Zhang, Yi
PMID: 30200948
Journal: Int J Mol Med. 2018 Nov;42(5):2737-2749.
Title: Inhibition of lysyl oxidase expression by dextran sulfate affects invasion and migration of gastric cancer cells.
Author: Xu, Yuanyi|Wang, Xiaofei|Huang, Yunning|Ma, Yanmei|Jin, Xiu|Wang, Honghong|Wang, Juan
PMID: 30226558
Journal: Oncol Lett. 2018 Oct;16(4):5041-5049.
Title: Dextran sulfate inhibition on human gastric cancer cells invasion, migration and epithelial-mesenchymal transformation.
Author: Xu, Yuanyi|Jin, Xiu|Huang, Yunning|Wang, Juan|Wang, Xiaofei|Wang, Honghong
PMID: 30250571
Journal: Onco Targets Ther. 2018 Oct 10;11:6705-6722.
Title: Effects of proton pump inhibitors on reversing multidrug resistance via downregulating V-ATPases/PI3K/Akt/mTOR/HIF-1alpha signaling pathway through TSC1/2 complex and Rheb in human gastric adenocarcinoma cells in vitro and in vivo.
Author: Chen, Min|Lu, Jian|Wei, Wei|Lv, Ying|Zhang, Xiaoqi|Yao, Yuling|Wang, Lei|Ling, Tingsheng|Zou, Xiaoping
PMID: 30349304